Device and method for detecting melamine based on microfluidics

Abstract

The invention relates to the technical field of food quality inspection, and particularly discloses a device for detecting melamine based on microfluidics and a detection method, which are used for solving the problem of complex detection in the prior art. Comprising a detection box, a plurality of supporting legs are arranged at the lower end of the detection box, a collecting hopper for collecting materials is arranged at the bottom of the detection box, a discharging pipe for discharging materials is arranged at the lower end of the collecting hopper, an adding assembly for adding the materials is arranged at the upper end of the detection box, and a rotating column body is rotationally arranged in the detection box; according to the invention, sample filtration, protein precipitation, immunoreaction and colorimetric detection are integrated through a whole-process micro-fluidic chip, and capillary force driving and nano material signal enhancement are utilized to solve the problems of poor timeliness and poor portability of a traditional method and the complex and expensive pain points of an existing micro-fluidic technology.

Description

Technical Field

[0001] The present invention relates to the technical field of food quality inspection, and particularly to a device and a detection method for detecting melamine based on microfluidics. Background Art

[0002] Melamine is often used as a chemical raw material and is one of the raw materials for making plastics, coatings, adhesives, etc. The Kjeldahl method is often used to detect the protein content in food or feed. Due to its high nitrogen content, studies have shown that the intake of melamine is the cause of stone formation and diseases in animals and infants. The United Nations Food Standards Committee has set the safety limit of melamine in food at 2.5 mg / kg (19.8 μM), and 1 mg / kg (7.9 μM) for infant formula milk powder. In addition, according to the World Health Organization's International Agency for Research on Cancer, traditional melamine detection relies on chromatography (high-precision but requires large equipment) or immunochromatography (simple operation but insufficient sensitivity and complex pretreatment), making it difficult to meet the needs of on-site rapid detection.

[0003] Based on this, a device and a detection method for detecting melamine based on microfluidics are now provided, which can eliminate the drawbacks of existing devices. Summary of the Invention

[0004] The purpose of the present invention is to provide a device and a detection method for detecting melamine based on microfluidics, which solve the problem of complex detection in the prior art.

[0005] To achieve the above purpose, the present invention provides the following technical solutions:

[0006] A device for detecting melamine based on microfluidics includes a detection box. Multiple legs are provided at the lower end of the detection box. An aggregate hopper for collecting materials is provided at the bottom of the detection box. A discharge pipe for discharging materials is provided at the lower end of the aggregate hopper. An adding component for adding materials is provided at the upper end of the detection box. A rotating cylinder is rotatably provided inside the detection box. Positioning perforations and transmission perforations coaxial with the rotating cylinder are provided at both ends of the detection box. A flipping component for driving the rotating cylinder to rotate is provided outside the detection box where the transmission perforation is located. At least two detection chutes are distributed on the outer side of the rotating cylinder. A transmission cavity communicating with the detection chutes is provided at the central position of the rotating cylinder. A microfluidic chip detection block is slidably provided in each detection chute. The microfluidic chip detection block and the detection chute are connected by a reset component. A push column is provided at the central position of the lower end of the microfluidic chip detection block. A driven wheel is rotatably provided at the lower end of the push column. A jitter component for driving the microfluidic chip detection block to jitter to mix materials is provided on the detection box. A cleaning component for cleaning the surface of the microfluidic chip detection block is provided inside the detection box. The cleaning component, the flipping component, and the microfluidic chip detection block are electrically connected to a control panel.

[0007] On the basis of the above technical solution, the present invention also provides the following optional technical solution:

[0008] In an optional scheme: the cleaning component includes a scraper slide plate slidably arranged on the inner wall of the detection box, a scraper rubber strip is provided on the upper end of the scraper slide plate, at least one cleaning guide rod is set inside the detection box, the cleaning guide rod and the scraper slide plate are slidably arranged, and a driving screw is also threaded on the scraper slide plate, one end of the driving screw is rotatably connected to the inner wall of the detection box, and the other end of the driving screw is connected to the output end of the cleaning motor, a water spray pipe is arranged on the side of the scraper slide plate, a plurality of water spray holes are distributed on the upper end of the water spray pipe, and the water inlet end of the water spray pipe is connected to the water supply part.

[0009] In an optional solution: the water supply component includes a water tank fixed on the outside of the detection box, the water outlet of the water tank is connected to a water pump, and the water outlet of the water pump is connected to the water inlet of the water spray pipe through a water supply pipe.

[0010] In an optional scheme: the shaking assembly includes a mounting base arranged on the outside of the detection box, a toggle motor is installed on the mounting base, a toggle shaft is provided at the output end of the toggle motor, a toggle wheel group is provided at the output end of the toggle shaft, the position of the toggle wheel group corresponds to the position of the driven wheel, the toggle wheel group includes a vibration wheel, and a plurality of protrusions are distributed on the outside of the vibration wheel.

[0011] In an optional scheme: a thrust assembly is provided on the mounting seat to generate thrust for the microfluidic chip detection block on the lower side, and the thrust assembly includes a positioning cross bar fixedly connected to the mounting seat, the end of the positioning cross bar is fixedly connected to the pushing guide rod, an arc-shaped arch frame is provided below the pushing guide rod, the upper end of the arc-shaped arch frame is slidably arranged in the inner hole of the pushing guide rod, the arc-shaped arch frame is fixedly connected to the downward reset block on the outer side of the pushing guide rod through a downward reset spring, a downward pressing connecting rod is fixedly provided at the center position of the arc-shaped arch frame, a downward pressing driven wheel is rotatably provided on the upper end of the downward pressing connecting rod, and the downward pressing driven wheel corresponds to the position of the toggle wheel group.

[0012] In an optional solution: the reset component includes a guide vertical rod symmetrically arranged at the lower end of the microfluidic chip detection block, the outer sliding sleeve of the guide vertical rod is provided with a guide side plate, the outer side of the guide side plate is connected and fixed to the inner wall of the detection slide groove, and the microfluidic chip detection block and the guide side plate are connected by a reset spring.

[0013] In an optional solution: the flipping assembly includes a worm wheel coaxially arranged with the rotating cylinder, the worm wheel is connected to the rotating cylinder via a connecting shaft, the upper side of the worm wheel is meshed with a worm, one end of the worm is rotatably connected to a fixed block outside the detection box, and the other end of the worm is fixedly connected to the output end of the flipping motor.

[0014] In an alternative solution: The adding component includes a feeding base sleeve arranged at the upper end of the detection box. The upper end of the feeding base sleeve matches the diameter of the injection syringe. A rubber block is provided at the center of the bottom of the feeding base sleeve. A piston block is slidably fitted in the injection syringe. The upper end of the piston block is connected to the injection rod. An injection needle for piercing the bottom of the injection syringe is provided at the lower end of the injection cavity.

[0015] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0016] 1. This design integrates sample filtration, protein precipitation, immune reaction and colorimetric detection through a full-process microfluidic chip. By utilizing capillary force drive and nanomaterial signal enhancement, rapid quantification with a detection limit of 0.5 mg / kg within 5 - 10 minutes is achieved, solving the pain points of poor timeliness, insufficient portability of traditional methods and the complexity and high cost of existing microfluidic technologies, and is applicable to on-site screening of dairy products, feeds, etc.

[0017] 2. After a single inspection, this application switches the test position by flipping and rotating the column body. Here, two working positions are designed for switching without waiting, greatly improving the test efficiency. Description of the Drawings

[0018] Figure 1 It is a schematic structural diagram of one side of the present invention.

[0019] Figure 2 It is a schematic structural diagram of the other side of the present invention.

[0020] Figure 3 It is a schematic internal structural diagram of the present invention.

[0021] Figure 4 It is of the present invention Figure 3 partial enlarged view.

[0022] Figure 5 It is a schematic structural diagram of one side of the rotating column body of the present invention.

[0023] Figure 6 It is a schematic structural diagram of the other side of the rotating column body of the present invention.

[0024] Figure 7 It is a schematic structural diagram of the bottom of the microfluidic chip detection block of the present invention.

[0025] Figure 8 It is a schematic structural diagram of the arc-shaped arch frame of the present invention.

[0026] Annotation of reference numerals: Detection box 100, Control panel 101, Feeding base sleeve 102, Positioning perforation 103, Leg 104, Aggregate hopper 105, Discharge pipe 106, Transmission perforation 107;

[0027] Injection syringe 200, piston block 201, injection chamber 202, injection needle 203;

[0028] Rotating cylinder 300, microfluidic chip detection block 301, detection slide 302, push column 303, driven wheel 304, guide vertical rod 305, guide side plate 306, return spring 307, push guide rod 308;

[0029] A downward pressing guide rod 308, a downward pressing reset block 309, a downward pressing reset spring 310, an arc-shaped arch frame 311, a positioning cross bar 312, a toggle motor 313, a mounting seat 314, a toggle shaft rod 315, a transmission cavity 316, and a toggle wheel set 317;

[0030] Worm 318, worm wheel 319, pressing connecting rod 320, pressing driven wheel 321, turning motor 322;

[0031] Water tank 400 , cleaning motor 401 , water pump 402 , water supply pipe 403 , scraper slide plate 404 , water spray pipe 405 , drive screw 406 , cleaning guide rod 407 . DETAILED DESCRIPTION

[0032] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0033] like Figures 1-8As shown in the figure, an embodiment of the present invention provides a device for detecting melamine based on microfluidics, which includes a detection box 100. A plurality of legs 104 are provided at the lower end of the detection box 100. An aggregate hopper 105 for aggregating materials is provided at the bottom of the detection box 100. A discharge pipe 106 for discharging materials is provided at the lower end of the aggregate hopper 105. An adding component for adding materials is provided at the upper end of the detection box 100. A rotating cylinder 300 is rotatably provided inside the detection box 100. Positioning through holes 103 and transmission through holes 107 coaxial with the rotating cylinder 300 are provided at both ends of the detection box 100. A turning component for driving the rotating cylinder 300 to rotate is provided outside the detection box 100 where the transmission through hole 107 is located. At least two detection chutes 302 are distributed on the outside of the rotating cylinder 300. A transmission cavity 316 communicating with the detection chutes 302 is provided at the central position of the rotating cylinder 300. A microfluidic chip detection block 301 is slidably provided in each detection chute 302. The microfluidic chip detection block 301 is connected to the detection chute 302 through a reset component. A push column 303 is provided at the central position of the lower end of the microfluidic chip detection block 301. A driven wheel 304 is rotatably provided at the lower end of the push column 303. A shaking component for driving the microfluidic chip detection block 301 to shake so as to mix the materials is provided on the detection box 100. A cleaning component for cleaning the surface of the microfluidic chip detection block 301 is provided inside the detection box 100. The cleaning component, the turning component and the microfluidic chip detection block 301 are electrically connected to a control panel 101.

[0034] The cleaning component includes a scraping slide plate 404 slidably provided on the inner wall of the detection box 100. At least one cleaning guide rod 407 is provided inside the detection box 100. The cleaning guide rod 407 is slidably provided with the scraping slide plate 404. A driving screw 406 is also threadedly provided on the scraping slide plate 404. One end of the driving screw 406 is rotatably connected to the inner wall of the detection box 100. The other end of the driving screw 406 is connected to the output end of a cleaning motor 401. Driven by the cleaning motor 401, the driving screw 406 rotates relative to the scraping slide plate 404. Under the action of the thread, the scraping slide plate 404 will slide along the inner wall of the detection box 100 to provide displacement power for cleaning. A water spraying pipe 405 is arranged on the side surface of the scraping slide plate 404. A plurality of water spraying holes are distributed at the upper end of the water spraying pipe 405. The water inlet end of the water spraying pipe 405 is connected to a water supply component. Under the action of the water supply component, cleaning water enters the water spraying pipe 405, and the sprayed water will assist in removing the attachments on the surface of the microfluidic chip detection block 301;

[0035] The water supply part includes a water tank 400 fixed on the outside of the detection box 100, the water outlet of the water tank 400 is connected to the water pump 402, and the water outlet of the water pump 402 is connected to the water inlet of the water spray pipe 405 through the water supply pipe 403, so that under the action of the water pump 402, the liquid enters the water spray pipe 405 along the water supply pipe 403, thereby providing a water source for cleaning;

[0036] The shaking assembly includes a mounting base 314 arranged outside the detection box 100, and a toggle motor 313 is installed on the mounting base 314. A toggle shaft 315 is provided at the output end of the toggle motor 313, and a toggle wheel group 317 is provided at the output end of the toggle shaft 315. The position of the toggle wheel group 317 corresponds to the position of the driven wheel 304. The toggle wheel group 317 includes a vibration wheel, and a plurality of protrusions are distributed on the outer side of the vibration wheel. In this way, under the drive of the toggle motor 313, the toggle shaft 315 drives the toggle wheel group 317 to rotate, and the toggle wheel group 317 will generate a driving force on the driven wheel 304, so that the microfluidic chip detection block 301 is continuously shaken, so as to fully mix the target material;

[0037] The mounting seat 314 is provided with a thrust component that generates thrust for the microfluidic chip detection block 301 on the lower side, so that the reaction surface of the microfluidic chip detection block 301 can be moved out of the detection slide groove 302, so as to clean the microfluidic chip detection block 301. The thrust component includes a positioning cross bar 312 connected and fixed to the mounting seat 314, and the end of the positioning cross bar 312 is fixedly connected to the pushing guide rod 308. An arc-shaped arch frame 311 is provided below the pushing guide rod 308. The upper end of the arc-shaped arch frame 311 is slidably set with the inner hole of the pushing guide rod 308. The arc-shaped arch frame 311 is fixedly connected to the downward reset block 309 on the outer side of the pushing guide rod 308 through a downward reset spring 310. The center position of the arc-shaped arch frame 311 is fixedly provided with a downward pressing connecting rod 32 0, the upper end of the pressing connecting rod 320 is rotatably provided with a pressing driven wheel 321, and the pressing driven wheel 321 corresponds to the position of the toggle wheel group 317. When the microfluidic chip detection block 301 rotates to the bottom along with the rotating cylinder 300, the driven wheel 304 is pressed by the arc surface of the arc-shaped arch frame 311, and the driven wheel 304 will drive the microfluidic chip detection block 301 to slide along the inner wall of the detection slide groove 302 through the pushing column 303, so that the reaction surface of the microfluidic chip detection block 301 slides out of the detection slide groove 302, so as to clean the surface of the microfluidic chip detection block 301, and the toggle wheel group 317 will synchronously generate a driving force for the pressing driven wheel 321, so that the arc-shaped arch frame 311 reciprocates and shakes, thereby improving the cleaning effect of the microfluidic chip detection block 301;

[0038] The reset assembly includes guiding vertical rods 305 symmetrically arranged at the lower end of the microfluidic chip detection block 301. A guiding side plate 306 is slidably sleeved outside the guiding vertical rods 305. The outer side of the guiding side plate 306 is fixedly connected to the inner wall of the detection chute 302. The microfluidic chip detection block 301 is connected to the guiding side plate 306 through a reset spring 307. Under the traction of the reset spring 307, the microfluidic chip detection block 301 will stay at a predetermined position in the detection chute 302;

[0039] The flipping assembly includes a worm gear 319 coaxially arranged with the rotating cylinder 300. The worm gear 319 is connected to the rotating cylinder 300 through a connecting shaft. The upper side of the worm gear 319 meshes with a worm 318. One end of the worm 318 is rotatably connected to a fixed block outside the detection box 100. The other end of the worm 318 is fixedly connected to the output end of a flipping motor 322. The base of the flipping motor 322 is fixedly connected to the outside of the detection box 100. Driven by the flipping motor 322, the worm 318 and the worm gear 319 cooperate to drive the rotating cylinder 300 to rotate, thereby driving the rotating cylinder 300 to flip;

[0040] The adding assembly includes a feeding base sleeve 102 arranged at the upper end of the detection box 100. The upper end of the feeding base sleeve 102 matches the diameter of the syringe 200. A rubber block is provided at the center of the bottom of the feeding base sleeve 102 for easy piercing by the injection needle 203. A piston block 201 is slidably fitted in the syringe 200. The upper end of the piston block 201 is connected to an injection rod. The lower end of the injection cavity 202 is provided with an injection needle 203 that pierces the bottom of the syringe 200. In this way, target materials such as samples and test raw materials can be stored in the syringe 200. First, insert the syringe 200 into the feeding base sleeve 102, and the injection needle 203 pierces the rubber block at the center of the bottom of the syringe 200. Then, by pushing the piston block 201, the material enters the detection box 100 to complete the addition of the material.

[0041] Working principle: During actual use, add samples and test liquid medicines to the surface of the microfluidic chip detection block 301 through the adding assembly. Combine melamine in the sample with colloidal gold antibody to inhibit its binding with the T-line conjugate. The unbound colloidal gold antibody binds to the secondary antibody when flowing through the C-line, forming a red strip. Result interpretation: The color depth of the T-line is inversely proportional to the concentration of melamine. The C-line is used as a quality control. An LED light source (520nm) + a photodiode are used to measure the absorbance of the T-line and the C-line. Take a picture of the chip image, analyze the color intensity through the APP, establish an absorbance-concentration standard curve, and calculate the result through linear regression. The concentration value is displayed on the screen, and a red alarm is given when it exceeds the standard;

[0042] During the test, the toggle shaft 315 drives the toggle wheel set 317 to rotate under the drive of the toggle motor 313, and the toggle wheel set 317 generates a driving force on the driven wheel 304, so that the microfluidic chip detection block 301 is constantly shaken, so as to fully mix the target material and speed up the reaction speed;

[0043] After completing a single test, the rotating cylinder 300 is driven to rotate through the flipping assembly. When the microfluidic chip detection block 301 rotates to the bottom with the rotating cylinder 300, the driven wheel 304 is pressed by the arc surface of the arc-shaped arch 311. The driven wheel 304 will drive the microfluidic chip detection block 301 to slide along the inner wall of the detection groove 302 through the pushing column 303, so that the reaction surface of the microfluidic chip detection block 301 slides out of the detection groove 302, so as to clean the surface of the microfluidic chip detection block 301, and the toggle wheel group 317 will synchronously generate a driving force for pressing down the driven wheel 321, so that the arc-shaped arch 311 shakes back and forth, cooperating with the cleaning assembly, thereby improving the cleaning effect of the microfluidic chip detection block 301.

[0044] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A device for detecting melamine based on microfluidics, comprising a detection box (100), wherein an adding component for adding materials is provided at the upper end of the detection box (100), a rotating cylinder (300) is rotatably provided inside the detection box (100), and positioning holes (103) and transmission holes (107) are provided at both ends of the detection box (100) and are arranged coaxially with the rotating cylinder (300); Features: A flip assembly for driving the rotating cylinder (300) to rotate is arranged on the outside of the detection box (100) where the transmission through hole (107) is located. At least two detection chutes (302) are distributed on the outside of the rotating cylinder (300). A transmission cavity (316) communicating with the detection chutes (302) is arranged at the center of the rotating cylinder (300). A microfluidic chip detection block (301) is slidably arranged in each detection chutes (302). The microfluidic chip detection block (301) is connected to the detection chutes (302) via a reset assembly. A push column (303) is arranged at the center of the lower end of the microfluidic chip detection block (301). A driven wheel (304) is rotatably arranged at the lower end of the push column (303). A shaking assembly for driving the microfluidic chip detection block (301) to shake so as to mix materials is arranged on the detection box (100). A cleaning assembly for cleaning the surface of the microfluidic chip detection block (301) is arranged inside the detection box (100).

2. The device for detecting melamine based on microfluidics according to claim 1, characterized in that: The cleaning assembly comprises a scraper slide plate (404) slidably arranged on the inner wall of the detection box (100), a scraper rubber strip is arranged on the upper end of the scraper slide plate (404), at least one cleaning guide rod (407) is arranged inside the detection box (100), the cleaning guide rod (407) and the scraper slide plate (404) are slidably arranged, a driving screw rod (406) is also threadedly arranged on the scraper slide plate (404), one end of the driving screw rod (406) is rotatably connected to the inner wall of the detection box (100), and the other end of the driving screw rod (406) is connected to the output end of the cleaning motor (401), a water spray pipe (405) is arranged on the side of the scraper slide plate (404), a plurality of water spray holes are distributed on the upper end of the water spray pipe (405), and the water inlet end of the water spray pipe (405) is connected to a water supply member.

3. The device for detecting melamine based on microfluidics according to claim 2, characterized in that: The water supply component comprises a water tank (400) fixed outside the detection box (100), the water outlet end of the water tank (400) is connected to a water pump (402), and the water outlet end of the water pump (402) is connected to a water inlet end of a water spray pipe (405) through a water supply pipe (403).

4. The device for detecting melamine based on microfluidics according to claim 1, characterized in that: The shaking assembly comprises a mounting seat (314) arranged outside the detection box (100), a toggle motor (313) is mounted on the mounting seat (314), an output end of the toggle motor (313) is provided with a toggle shaft (315), an output end of the toggle shaft (315) is provided with a toggle wheel group (317), the position of the toggle wheel group (317) corresponds to the position of the driven wheel (304), and the toggle wheel group (317) comprises a vibration wheel, and a plurality of protrusions are distributed on the outer side of the vibration wheel.

5. The device for detecting melamine based on microfluidics according to claim 4, characterized in that: The mounting seat (314) is provided with a thrust assembly for generating thrust for the microfluidic chip detection block (301) on the lower side, the thrust assembly comprising a positioning cross bar (312) connected and fixed to the mounting seat (314), the end of the positioning cross bar (312) being fixedly connected to the pushing guide rod (308), an arc-shaped arch frame (311) being provided below the pushing guide rod (308), the upper end of the arc-shaped arch frame (311) being slidably arranged with the inner hole of the pushing guide rod (308), the arc-shaped arch frame (311) being fixedly connected with the downward pressing reset block (309) on the outer side of the pushing guide rod (308) through a downward pressing reset spring (310), a downward pressing connecting rod (320) being fixedly provided at the center position of the arc-shaped arch frame (311), a downward pressing driven wheel (321) being rotatably provided at the upper end of the downward pressing connecting rod (320), and the downward pressing driven wheel (321) corresponding to the position of the toggle wheel group (317).

6. The device for detecting melamine based on microfluidics according to claim 1, characterized in that: The reset component comprises a guide vertical rod (305) symmetrically arranged at the lower end of the microfluidic chip detection block (301); a guide side plate (306) is slidably sleeved on the outer side of the guide vertical rod (305); the outer side of the guide side plate (306) is connected and fixed to the inner wall of the detection slide groove (302); and the microfluidic chip detection block (301) and the guide side plate (306) are connected via a reset spring (307).

7. The device for detecting melamine based on microfluidics according to claim 1, characterized in that: The flip assembly includes a worm gear (319) coaxially arranged with the rotating cylinder (300), the worm gear (319) being connected to the rotating cylinder (300) via a connecting shaft, the upper side of the worm gear (319) being meshed with a worm (318), one end of the worm (318) being rotatably connected to a fixed block outside the detection box (100), and the other end of the worm (318) being fixedly connected to an output end of a flip motor (322).

8. The device for detecting melamine based on microfluidics according to claim 1, characterized in that: The adding component comprises a discharge base sleeve (102) arranged at the upper end of the detection box (100), the upper end of the discharge base sleeve (102) matches the diameter of the injection syringe (200), a rubber block is provided at the center of the bottom of the discharge base sleeve (102), a piston block (201) is provided in a sliding fit in the injection syringe (200), the upper end of the piston block (201) is connected to the injection rod, and the lower end of the injection cavity (202) is provided with an injection needle (203) that pierces the bottom of the injection syringe (200).

9. A device for detecting melamine based on microfluidics according to any one of claims 1 to 8, characterized in that: The following steps are involved: Step 1: Add the sample and the test solution to the surface of the microfluidic chip detection block (301) through the adding component, analyze the color intensity through the APP, establish the absorbance-concentration standard curve, calculate the result through linear regression, and display the concentration value on the screen. When it exceeds the standard, a red alarm will be issued; Step 2: During the test, the toggle shaft (315) drives the toggle wheel set (317) to rotate under the drive of the toggle motor (313), and the toggle wheel set (317) generates a driving force on the driven wheel (304), so that the microfluidic chip detection block (301) is constantly shaken, so as to fully mix the target material and accelerate the reaction speed; Step 3: After completing a single test, the rotating cylinder (300) is driven to rotate by the flipping assembly. When the microfluidic chip detection block (301) rotates to the bottom along with the rotating cylinder (300), the cleaning assembly is used to clean the tested microfluidic chip detection block (301).

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