Xiangdan injection as well as preparation device and preparation process thereof

Abstract

The invention belongs to the technical field of medical instruments, and particularly discloses a Xiangdan injection and a preparation device and process thereof.The Xiangdan injection comprises a split charging barrel, a partition plate is fixed to the position, located in the middle, of the inner wall of the split charging barrel, a plurality of cooling flow dividing assemblies are arranged at the bottom of the partition plate at equal intervals, and a cylindrical cavity is formed in the bottom of the partition plate; according to the device, a mixed solution mixed with a radix salviae miltiorrhizae extract, a lignum dalbergiae odoriferae extract, glucose liquid, glycine, salvianolic acid A and salvianolic acid B is injected into the split charging barrel through a material injection pipe, at the moment, the mixed solution is located above a protection plate in the split charging barrel, and then a stepping motor is started to drive filtering assemblies to work in sequence; therefore, the mixed solution can be discharged into the cooling and shunting assembly at intervals in a small batch to be cooled, the filtering assembly is driven to work, meanwhile, the cleaning assembly is driven to remove impurities filtered by the filtering assembly, and meanwhile, the sewage discharging assembly is driven to discharge the impurities removed by the cleaning assembly.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly relates to a salvia miltiorrhiza and borneol injection, a preparation device thereof, and a preparation process thereof. Background Art

[0002] Salvia miltiorrhiza and borneol injection is a pure traditional Chinese medicine preparation for treating vasodilation, increasing coronary blood flow, which can be used for angina pectoris and also for myocardial infarction. Inevitably, impurities will appear in the liquid medicine of this pure traditional Chinese medicine preparation injection, and the impurities in the liquid medicine will cause hypersensitivity reactions. Therefore, it is necessary to filter out the impurities as much as possible when preparing the liquid medicine.

[0003] Currently, when producing salvia miltiorrhiza and borneol injection, it is necessary to purify and filter the liquid medicine and then cool and package it. However, during the purification and filtration, if the filter surface of the concentrated purification filter screen of the liquid medicine is not cleaned in time, the filtering effect of the filter screen will decline, resulting in a relatively large amount of impurities doped in the liquid medicine, which is not convenient for subsequent process treatment. Summary of the Invention

[0004] In order to solve the problems existing in the prior art, the present invention provides a salvia miltiorrhiza and borneol injection, a preparation device thereof, and a preparation process thereof.

[0005] To achieve the above object, the present invention adopts the following technical solution: A preparation device for salvia miltiorrhiza and borneol injection, including a dispensing cylinder, a partition is fixedly arranged in the middle between the inner walls of the dispensing cylinder, a plurality of cooling and diversion components are equidistantly arranged at the bottom of the partition, a cylindrical cavity is opened at the bottom of the partition, a plurality of reciprocating cavities connected to the cooling and diversion components are equidistantly opened at the top of the partition, filtering components are arranged inside the plurality of reciprocating cavities, cleaning components are arranged at the opening parts of the plurality of reciprocating cavities at the top of the partition, a conical groove is opened in the middle at the top of the partition, and a sewage discharging component is arranged inside the conical groove;

[0006] A plurality of exhaust ports are equidistantly opened along the circumferential direction at the inner bottom surface of the dispensing cylinder near the outer surface edge, two feeding pipes are communicated with the top of the dispensing cylinder, a flange ring is fixedly arranged at the outer surface of the dispensing cylinder near the top edge, a bottom cover is arranged in the middle at the bottom of the dispensing cylinder, a bracket is fixedly arranged between the inner walls of the cylindrical cavity, a stepping motor is fixed on the bracket, an output end of the stepping motor is fixed with a driving disk, and the top of the driving disk is inclined and located inside the cylindrical cavity.

[0007] Preferably, the cooling diversion assembly includes a spiral tube, the top of the spiral tube is fixed to the bottom of the partition plate, the bottom of the spiral tube penetrates below the bottom cover, a diversion channel is opened on the inner bottom surface of the reciprocating cavity, one end of the diversion channel is communicated with the top of the spiral tube, an annular cavity is opened in the partition plate, a gas supply pipe is arranged on the outer surface of the dispensing cylinder, one end of the gas supply pipe is communicated with the inside of the annular cavity, an annular groove is opened on the inner wall of the cylindrical cavity, and the top of the annular groove is communicated with the bottom of the annular cavity.

[0008] Preferably, a limiting ring is slidably arranged in the annular groove, the inner wall of the limiting ring is fixed to the outer surface of the driving disc, a through hole penetrating to the bottom is opened at a position close to one side edge of the top of the limiting ring, a spray head is fixed to one side of the spiral tube at the bottom of the partition plate, the top of the spray head is communicated with the inner bottom surface of the annular groove, a guide plate is obliquely fixed to one side of the spray head at the bottom of the partition plate, and the bottom of the guide plate obliquely extends towards the spiral tube side.

[0009] Preferably, the filtering assembly includes a filter cylinder, the filter cylinder is slidably arranged between the inner walls of the reciprocating cavity, a fixed pipe is installed on the inner bottom surface of the reciprocating cavity, the bottom of the fixed pipe is communicated with the diversion channel, the top of the fixed pipe is closed, and the top of the fixed pipe slidably penetrates into the filter cylinder, and a plurality of through holes penetrating to the inside are equidistantly opened in the circumferential direction at a position close to the bottom edge of the outer surface of the fixed pipe.

[0010] Preferably, a protection plate is fixed between the inner walls of the dispensing cylinder above the partition plate, the top of the filter cylinder slidably penetrates above the protection plate, a plurality of support rods are equidistantly fixed in the circumferential direction of the filter cylinder at the top of the protection plate, a circular plate is fixed between the tops of the plurality of support rods, the circular plate is located directly above the filter cylinder, a return spring is fixed between the bottom of the circular plate and the top of the filter cylinder, filter meshes are arranged at the positions close to the top edges on both inner walls of the filter cylinder, a gap exists between the bottom of the protection plate and the top of the partition plate, and a thread line is arranged on the outer surface of the filter cylinder.

[0011] Preferably, a side opening penetrating to the inside of the cylindrical cavity is opened on one side of the reciprocating cavity, a dial plate is fixed to the outer surface of one side of the filter cylinder, the dial plate is slidably attached to the inner walls on both sides of the side opening, and one end of the dial plate extends into the cylindrical cavity and is attached to the inclined part of the top of the driving disc.

[0012] Preferably, the cleaning component includes a fixing ring fixed to the top of the partition plate. The top of the fixing ring is fixed to the bottom of the protection plate. The filter cartridge is located inside the fixing ring. A rotating ring is rotatably arranged between the inner walls of the fixing ring. A plurality of brush strips are fixed to the inner wall of the rotating ring. The inner sides of the brush strips are in mutual contact with the outer surface of the filter cartridge. An internal thread ring is fixed to the bottom of the rotating ring. The inner wall of the internal thread ring is in threaded connection with the outer surface of the filter cartridge.

[0013] Preferably, the sewage discharge component includes a spiral blade rod. A conical groove is formed in the middle of the top of the partition plate. The spiral blade rod is rotatably connected to the inner bottom surface of the conical groove. A convex disk is fixed to the inner top surface of the cylindrical cavity. A transmission cavity is formed inside the convex disk. A transmission disk is rotatably arranged between the inner walls of the transmission cavity. A storage groove penetrating to the bottom is formed at one side edge near the top of the transmission disk. An indentation penetrating to the inside of the transmission cavity is formed at one side edge near the inner bottom surface of the conical groove. The bottom of the spiral blade rod is fixedly connected to the transmission disk. The bottom of the transmission disk penetrates to the inside of the cylindrical cavity and is fixedly connected to the driving disk. A sewage discharge pipe is fixed to one side edge near the bottom of the convex disk. One end of the sewage discharge pipe penetrates to the inside of the transmission cavity. The other end of the sewage discharge pipe penetrates to the outside of the sub-packaging cylinder.

[0014] The present invention also provides a preparation process for salvia miltiorrhiza and borneol injection, which is applied to a preparation device for salvia miltiorrhiza and borneol injection. The preparation process for salvia miltiorrhiza and borneol injection includes the following steps:

[0015] Step S1: Inject a mixed solution containing salvia miltiorrhiza extract, borneol extract, glucose solution, glycine, salvianolic acid A and salvianolic acid B into the inside of the sub-packaging cylinder through a feeding pipe. At this time, the mixed solution is located above the protection plate inside the sub-packaging cylinder. Then, start the stepping motor to drive the filtering component to work in sequence, so that the mixed solution can be discharged into the cooling and shunting component for cooling in small batches at intervals. And while driving the filtering component to work, it will also drive the cleaning component to remove the impurities filtered by the filtering component, and at the same time drive the sewage discharge component to discharge the impurities removed by the cleaning component.

[0016] Step S2: When the filtering component works, the driving disk is driven to rotate by the stepper motor. During the rotation, since the inclined surface at the top of the driving disk is in contact with one end of the dial plate, the dial plate will be driven to move up and down, and then the filter cartridge will be driven to move up and down. During the upward movement of the filter cartridge, when the filter screen part rises above the protection plate, the mixed solution located above the protection plate can flow into the interior of the filter cartridge after being filtered through the filter screen. Then, during the downward movement of the filter cartridge, since the inner wall of the filter cartridge is in contact with the inner wall of the reciprocating chamber, the mixed solution inside the filter cartridge will not flow into the interior of the reciprocating chamber until the filter cartridge descends to the inner bottom surface of the reciprocating chamber and the leak port on the fixed pipe slides into the interior of the filter cartridge. At this time, the mixed liquid inside the filter cartridge can flow into the drainage channel from the leak port;

[0017] Step S3: When the cleaning component works, when the filter cartridge moves up and down, since the outer surface of the filter cartridge is threadedly connected to the internal thread ring, the internal thread ring will be driven to rotate, and then the rotating ring will be driven to drive the brush strip to clean the outer surface of the filter cartridge. The dirty liquid generated after cleaning will be retained in the gap between the top of the partition plate and the bottom of the protection plate;

[0018] Step S4: When the sewage discharge component works, when the driving disk rotates, it will also synchronously drive the transmission disk and the spiral blade rod to rotate. The rotation of the spiral blade rod can gather the liquid in the gap between the top of the partition plate and the bottom of the protection plate towards the middle part for subsequent discharge. When the transmission disk rotates, when the storage groove on the transmission disk rotates to the bottom of the notch, the dirty liquid located inside the notch and inside the conical groove can flow into the storage groove for storage. When the storage groove slides to the connection part of the sewage discharge pipe and the transmission cavity, the dirty solution located inside the storage groove can be discharged to the outside through the sewage discharge pipe;

[0019] Step S5: When the cooling and diversion component works, when the mixed liquid inside the filter cartridge can flow into the drainage channel from the leak port, the liquid will flow into the interior of the spiral pipe through the drainage channel. And while discharging the liquid, the through hole on the limiting ring will rotate to the connection part of the spray head and the annular groove, so that the spray head is communicated with the annular cavity through the through hole. At this time, the cold air supplied by the air supply pipe to the interior of the annular cavity can flow to the spray head through the through hole, and under the action of the spray head and in cooperation with the diversion plate, the cold air can flow evenly to the spiral pipe to cool the solution inside the spiral pipe.

[0020] The present invention also provides a salvia miltiorrhiza injection, which is prepared by using a preparation process of a salvia miltiorrhiza injection, and comprises the following raw materials: 1 - 3 parts of salvia miltiorrhiza extract, 1 - 3.5 parts of lignum dalbergiae odoriferae extract, 12 - 18 parts of glucose solution, 4 - 8 parts of glycine, 0.05 part of salvianolic acid A, and 0.04 - 0.06 part of salvianolic acid B.

[0021] Compared with the prior art, the beneficial effects of the present invention are:

[0022] 1. In the present invention, a mixed solution containing salvia miltiorrhiza extract, dalbergia odorifera extract, glucose solution, glycine, salvianolic acid A, and salvianolic acid B is injected into the interior of a dispensing cylinder through a feeding pipe. At this time, the mixed solution is located above the protective plate inside the dispensing cylinder. Then, by starting a stepper motor to drive the filtering component to work in sequence, the mixed solution can be discharged into the cooling and diverting component for cooling in small batches at intervals. Meanwhile, when driving the filtering component to work, the cleaning component will be driven to remove the impurities filtered by the filtering component, and at the same time, the sewage discharging component will be driven to discharge the impurities removed by the cleaning component;

[0023] 2. When the filtering component works, during the upward movement of the filter cylinder, when the filter screen part rises above the protective plate, the mixed solution located above the protective plate can flow into the interior of the filter cylinder after being filtered by the filter screen. Then, during the downward movement of the filter cylinder, since the inner wall of the filter cylinder fits with the inner wall of the reciprocating cavity, the mixed solution inside the filter cylinder will not flow into the interior of the reciprocating cavity until the filter cylinder descends to the inner bottom surface of the reciprocating cavity and the leak hole on the fixed pipe slides into the interior of the filter cylinder. At this time, the mixed liquid inside the filter cylinder can flow into the drainage channel from the leak hole;

[0024] 3. When the cleaning component works, during the up and down movement of the filter cylinder, since the outer surface of the filter cylinder is threadedly connected to the internal thread ring, the internal thread ring will be driven to rotate, and then the rotating ring will be driven to drive the brush strip to clean the outer surface of the filter cylinder. The dirty liquid generated after cleaning will be retained in the gap between the top of the partition plate and the bottom of the protective plate;

[0025] 4. When the sewage discharging component works, during the rotation of the transfer disk, when the storage groove on the transfer disk rotates to the bottom of the notch, the dirty liquid located inside the notch and inside the conical groove can flow into the storage groove for storage. When the storage groove slides to the connection part of the sewage pipe and the transfer cavity, the dirty solution located inside the storage groove can be discharged to the outside through the sewage pipe;

[0026] 5. When the cooling and diverting component works, when the mixed liquid inside the filter cylinder can flow into the drainage channel from the leak hole, the liquid will flow into the interior of the spiral pipe through the drainage channel. Then, the cold air supplied to the annular cavity through the air supply pipe, under the action of the nozzle and in cooperation with the flow guiding plate, can make the cold air flow evenly towards the spiral pipe to cool the solution inside the spiral pipe. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 is a front perspective structural schematic diagram of a salvia miltiorrhiza and dalbergia odorifera injection preparation device proposed by the present invention;

[0028] Figure 2 is a bottom perspective structural schematic diagram of a salvia miltiorrhiza and dalbergia odorifera injection preparation device proposed by the present invention;

[0029] Figure 3This is a schematic perspective sectional view of one side of a preparation device for Salvia Miltiorrhiza and Danshen Injection proposed by the present invention;

[0030] Figure 4 This is a schematic perspective sectional view of the other side of a preparation device for Salvia Miltiorrhiza and Danshen Injection proposed by the present invention;

[0031] Figure 5 This is a schematic perspective front view of the internal structure of a preparation device for Salvia Miltiorrhiza and Danshen Injection proposed by the present invention;

[0032] Figure 6 This is a schematic perspective bottom view of the internal structure of a preparation device for Salvia Miltiorrhiza and Danshen Injection proposed by the present invention;

[0033] Figure 7 For the present invention Figure 3 The partial enlarged view at A in;

[0034] Figure 8 For the present invention Figure 3 The partial enlarged view at B in.

[0035] In the figure: 1, filling cylinder; 2, flange ring; 3, feeding pipe; 4, exhaust port; 5, bottom cover; 6, spiral pipe; 7, partition board; 8, circular plate; 9, support rod; 10, return spring; 11, sewage discharge pipe; 12, air supply pipe; 13, annular cavity; 14, cylindrical cavity; 15, annular groove; 16, limiting ring; 17, driving disc; 18, stepping motor; 19, bracket; 20, guide plate; 21, side port; 22, dialing plate; 23, reciprocating cavity; 24, fixed pipe; 25, leakage port; 26, drainage channel; 27, filter cartridge; 28, filter screen; 29, fixing ring; 30, rotating ring; 31, brush strip; 32, protection plate; 33, internal thread ring; 34, convex disc; 35, transmission cavity; 36, transmission disc; 37, storage tank; 38, constricted opening; 39, spiral blade rod; 40, conical groove; 41, through hole; 42, nozzle. Detailed implementation manners

[0036] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0037] Fermentation engineering refers to a new technology that uses modern engineering techniques to utilize certain specific functions of microorganisms to produce useful products for humans or directly apply microorganisms to the industrial production process. The content of fermentation engineering includes the selection and breeding of strains, the preparation of culture media, sterilization, enlarged cultivation and inoculation, the fermentation process, and the separation and purification of products. Currently, when producing lutein mushroom sauce through fermentation engineering, the specific production steps are as follows:

[0038] Please refer to Figures 1-8 , the present invention provides a technical solution: a preparation device for salvia miltiorrhiza injection, including a dispensing cylinder 1. A partition 7 is fixedly arranged in the middle between the inner walls of the dispensing cylinder 1. A plurality of cooling and diversion components are equidistantly arranged at the bottom of the partition 7. A cylindrical cavity 14 is opened at the bottom of the partition 7. A plurality of reciprocating cavities 23 connected to the cooling and diversion components are equidistantly opened at the top of the partition 7. Filter components are arranged inside a plurality of the reciprocating cavities 23. Cleaning components are arranged at the openings of a plurality of the reciprocating cavities 23 at the top of the partition 7. A conical groove 40 is opened in the middle at the top of the partition 7. A sewage discharge component is arranged inside the conical groove 40;

[0039] A plurality of exhaust ports 4 are equidistantly opened along the circumferential direction at the inner bottom surface of the dispensing cylinder 1 near the outer surface edge. Two feeding pipes 3 are communicated with the top of the dispensing cylinder 1. A flange ring 2 is fixedly arranged at the outer surface of the dispensing cylinder 1 near the top edge. A bottom cover 5 is arranged in the middle at the bottom of the dispensing cylinder 1. A bracket 19 is fixedly arranged between the inner walls of the cylindrical cavity 14. A stepping motor 18 is fixed on the bracket 19. The output end of the stepping motor 18 is fixed with a driving disk 17. The top of the driving disk 17 is inclined and is located inside the cylindrical cavity 14.

[0040] The achieved effect is that the mixed solution containing salvia miltiorrhiza extract, dalbergia odorifera extract, glucose solution, glycine, salvianolic acid A, and salvianolic acid B is injected into the inside of the dispensing cylinder 1 through the feeding pipe 3. At this time, the mixed solution is above the protective plate 32 inside the dispensing cylinder 1. Then, by starting the stepping motor 18 to drive the filter components to work in sequence, the mixed solution can be discharged into the cooling and diversion components for cooling in small batches at intervals. And while driving the filter components to work, it will also drive the cleaning components to remove the impurities filtered by the filter components, and at the same time drive the sewage discharge components to discharge the impurities removed by the cleaning components.

[0041] Such as Figure 2 、 Figure 4 、 Figure 6 and Figure 7As shown in the figure, the cooling diversion assembly includes a spiral tube 6. The top of the spiral tube 6 is fixed to the bottom of the partition plate 7, and the bottom of the spiral tube 6 penetrates below the bottom cover 5. A diversion channel 26 is provided on the inner bottom surface of the reciprocating cavity 23. One end of the diversion channel 26 is communicated with the top of the spiral tube 6. An annular cavity 13 is provided inside the partition plate 7. An air supply pipe 12 is arranged on the outer surface of the dispensing cylinder 1. One end of the air supply pipe 12 is communicated with the inside of the annular cavity 13. An annular groove 15 is provided on the inner wall of the cylindrical cavity 14. The top of the annular groove 15 is communicated with the bottom of the annular cavity 13. A limiting ring 16 is slidably arranged inside the annular groove 15. The inner wall of the limiting ring 16 is fixed to the outer surface of the driving disk 17. A through hole 41 penetrating to the bottom is provided near one side edge of the top of the limiting ring 16. A spray head 42 is fixed to the bottom of the partition plate 7 on one side of the spiral tube 6. The top of the spray head 42 is communicated with the inner bottom surface of the annular groove 15. A diversion plate 20 is obliquely fixed to the bottom of the partition plate 7 on one side of the spray head 42. The bottom of the diversion plate 20 extends obliquely towards the spiral tube 6 side.

[0042] The achieved effect is that when the mixed liquid inside the filter cartridge 27 flows into the diversion channel 26 from the leakage port 25, the liquid will flow into the inside of the spiral tube 6 through the diversion channel 26. And while discharging the liquid, the through hole 41 on the limiting ring 16 will rotate to the connection part of the spray head 42 and the annular groove 15, so that the spray head 42 is communicated with the annular cavity 13 through the through hole 41. At this time, the cold air supplied by the air supply pipe 12 to the inside of the annular cavity 13 can flow to the spray head 42 through the through hole 41. Under the action of the spray head 42 and in cooperation with the diversion plate 20, the cold air can flow evenly to the spiral tube 6 to cool the solution inside the spiral tube 6.

[0043] Such as Figure 3 、 Figure 5 and Figure 7As shown, the filtering component includes a filter cartridge 27. The filter cartridge 27 is slidably arranged between the inner walls of the reciprocating cavity 23. A fixed pipe 24 is installed on the inner bottom surface of the reciprocating cavity 23. The bottom of the fixed pipe 24 communicates with the drainage channel 26. The top of the fixed pipe 24 is closed, and the top of the fixed pipe 24 slidably penetrates into the interior of the filter cartridge 27. A plurality of leakage ports 25 penetrating to the interior are equidistantly arranged along the circumferential direction near the bottom edge of the outer surface of the fixed pipe 24. A protective plate 32 is fixed between the inner walls of the dispensing cylinder 1 above the partition plate 7. The top of the filter cartridge 27 slidably penetrates above the protective plate 32. A plurality of support rods 9 are fixedly arranged at equal intervals in the circumferential direction of the filter cartridge 27 on the top of the protective plate 32. A circular plate 8 is fixed between the tops of the plurality of support rods 9. The circular plate 8 is located directly above the filter cartridge 27. A return spring 10 is fixed between the bottom of the circular plate 8 and the top of the filter cartridge 27. Filter meshes 28 are arranged at the top edges of both inner walls of the filter cartridge 27. There is a gap between the bottom of the protective plate 32 and the top of the partition plate 7. The outer surface of the filter cartridge 27 has a thread. A side port 21 penetrating into the interior of the cylindrical cavity 14 is opened on one side of the reciprocating cavity 23. A dial plate 22 is fixed on the outer surface of one side of the filter cartridge 27. The dial plate 22 is slidably fitted between the inner walls on both sides of the side port 21. One end of the dial plate 22 extends into the interior of the cylindrical cavity 14 and is in contact with the inclined part at the top of the driving disk 17.

[0044] The achieved effect is that the stepping motor 18 drives the driving disk 17 to rotate. During the rotation, since the inclined surface at the top of the driving disk 17 is in contact with one end of the dial plate 22, the dial plate 22 will be driven to move up and down, and then the filter cartridge 27 will be driven to move up and down. During the upward movement of the filter cartridge 27, when the filter mesh 28 part rises above the protective plate 32, the mixed solution above the protective plate 32 can flow into the interior of the filter cartridge 27 after being filtered by the filter mesh 28. Then, during the downward movement of the filter cartridge 27, since the inner wall of the filter cartridge 27 is in contact with the inner wall of the reciprocating cavity 23, the mixed solution inside the filter cartridge 27 will not flow into the interior of the reciprocating cavity 23 until the filter cartridge 27 descends to the inner bottom surface of the reciprocating cavity 23 and the leakage ports 25 on the fixed pipe 24 slide into the interior of the filter cartridge 27. At this time, the mixed liquid inside the filter cartridge 27 can flow into the drainage channel 26 from the leakage ports 25.

[0045] As Figure 3 , Figure 4 and Figure 7 shown, the cleaning component includes a fixing ring 29. The fixing ring 29 is fixed on the top of the partition plate 7. The top of the fixing ring 29 is fixed to the bottom of the protective plate 32. The filter cartridge 27 is located inside the fixing ring 29. A rotating ring 30 is rotatably arranged between the inner walls of the fixing ring 29. A plurality of brush strips 31 are fixed to the inner wall of the rotating ring 30. The inner sides of the brush strips 31 are in contact with the outer surface of the filter cartridge 27. An internal thread ring 33 is fixed to the bottom of the rotating ring 30. The inner wall of the internal thread ring 33 is threadedly connected to the outer surface of the filter cartridge 27.

[0046] The achieved effect is that when the filter cartridge 27 moves up and down, due to the threaded connection between the outer surface of the filter cartridge 27 and the internal thread ring 33, the internal thread ring 33 will be driven to rotate, and then the rotating ring 30 will drive the brush strip 31 to clean the outer surface of the filter cartridge 27. The dirty liquid generated after cleaning will be retained in the gap between the top of the partition plate 7 and the bottom of the protective plate 32.

[0047] Such as Figure 3 , Figure 4 and Figure 8 As shown, the sewage discharge assembly includes a spiral blade rod 39. A conical groove 40 is formed in the middle of the top of the partition plate 7. The spiral blade rod 39 is rotatably connected to the inner bottom surface of the conical groove 40. A convex disk 34 is fixed to the inner top surface of the cylindrical cavity 14. A transfer cavity 35 is formed inside the convex disk 34. A transfer disk 36 is rotatably arranged between the inner walls of the transfer cavity 35. A storage groove 37 penetrating through to the bottom is formed at the top of the transfer disk 36 near one side edge. An indentation 38 penetrating through to the inside of the transfer cavity 35 is formed at the inner bottom surface of the conical groove 40 near one side edge. The bottom of the spiral blade rod 39 is fixed to the transfer disk 36. The bottom of the transfer disk 36 penetrates into the inside of the cylindrical cavity 14 and is fixed to the drive disk 17. A sewage discharge pipe 11 is fixed to the bottom of the convex disk 34 near one side edge. One end of the sewage discharge pipe 11 penetrates into the inside of the transfer cavity 35, and the other end of the sewage discharge pipe 11 penetrates to the outside of the sub-packaging cylinder 1.

[0048] The achieved effect is that when the drive disk 17 rotates, the transfer disk 36 and the spiral blade rod 39 will also rotate synchronously. The rotation of the spiral blade rod 39 can gather the liquid in the gap between the top of the partition plate 7 and the bottom of the protective plate 32 to the middle part for subsequent discharge. When the transfer disk 36 rotates, when the storage groove 37 on the transfer disk 36 rotates to the bottom of the indentation 38, the dirty liquid in the indentation 38 and the conical groove 40 can flow into the storage groove 37 for storage. When the storage groove 37 slides to the connection part of the sewage discharge pipe 11 and the transfer cavity 35, the dirty solution in the storage groove 37 can be discharged to the outside through the sewage discharge pipe 11.

[0049] For example, in an embodiment, the present invention further provides a preparation process of salvia miltiorrhiza injection, which is applied to a salvia miltiorrhiza injection preparation device as described above, and includes the following steps:

[0050] Step S1: Inject the mixed solution containing salvia miltiorrhiza extract, dalbergia odorifera extract, glucose solution, glycine, salvianolic acid A and salvianolic acid B into the interior of the dispensing cylinder 1 through the feeding pipe 3. At this time, the mixed solution is located above the protection plate 32 inside the dispensing cylinder 1. Then, start the stepping motor 18 to drive the filtering component to work in sequence, so that the mixed solution can be intermittently discharged into the cooling and splitting component in small batches for cooling. At the same time as driving the filtering component to work, it will also drive the cleaning component to remove the impurities filtered by the filtering component, and at the same time drive the sewage discharging component to discharge the impurities removed by the cleaning component;

[0051] Step S2: When the filtering component works, the driving disk 17 is driven to rotate by the stepping motor 18. During the rotation, since the inclined surface at the top of the driving disk 17 is in contact with one end of the baffle 22, the baffle 22 will be driven to move up and down, and then the filter cylinder 27 will be driven to move up and down. During the upward movement of the filter cylinder 27, when the filter screen 28 rises above the protection plate 32, the mixed solution located above the protection plate 32 can flow into the interior of the filter cylinder 27 after being filtered by the filter screen 28. Then, during the downward movement of the filter cylinder 27, since the inner wall of the filter cylinder 27 is in contact with the inner wall of the reciprocating cavity 23, the mixed solution inside the filter cylinder 27 will not flow into the interior of the reciprocating cavity 23 until the filter cylinder 27 descends to the inner bottom surface of the reciprocating cavity 23 and the leak port 25 on the fixed pipe 24 slides into the interior of the filter cylinder 27. At this time, the mixed liquid inside the filter cylinder 27 can flow into the drainage channel 26 from the leak port 25;

[0052] Step S3: When the cleaning component works, when the filter cylinder 27 moves up and down, since the outer surface of the filter cylinder 27 is threadedly connected with the internal thread ring 33, the internal thread ring 33 will be driven to rotate, and then the rotating ring 30 will be driven to drive the brush strip 31 to clean the outer surface of the filter cylinder 27. The dirty liquid generated after cleaning will be stored in the gap between the top of the partition plate 7 and the bottom of the protection plate 32;

[0053] Step S4: When the sewage discharging component works, when the driving disk 17 rotates, it will also synchronously drive the transfer disk 36 and the spiral blade rod 39 to rotate. The rotation of the spiral blade rod 39 can gather the liquid in the gap between the top of the partition plate 7 and the bottom of the protection plate 32 towards the middle part for subsequent discharge. When the transfer disk 36 rotates, when the storage groove 37 on the transfer disk 36 rotates to the bottom of the notch 38, the dirty liquid located inside the notch 38 and inside the conical groove 40 can flow into the storage groove 37 for storage. When the storage groove 37 slides to the connection part of the sewage discharge pipe 11 and the transfer cavity 35, the dirty solution located inside the storage groove 37 can be discharged to the outside through the sewage discharge pipe 11;

[0054] Step S5: When the cooling and diversion assembly is working, when the mixed liquid inside the filter cartridge 27 can flow into the diversion channel 26 from the leakage port 25, the liquid will flow into the interior of the spiral tube 6 through the diversion channel 26. And while discharging the liquid, the through hole 41 on the limit ring 16 will rotate to the connection part of the nozzle 42 and the annular groove 15, so that the nozzle 42 is in communication with the annular cavity 13 through the through hole 41. At this time, the cold air supplied by the air supply pipe 12 to the interior of the annular cavity 13 can flow to the nozzle 42 through the through hole 41. Under the action of the nozzle 42 and in cooperation with the flow guide plate 20, the cold air can flow evenly to the spiral tube 6 to cool the solution inside the spiral tube 6.

[0055] For example, in one embodiment, the present invention also provides a salvia miltiorrhiza injection, which is prepared by a preparation process of salvia miltiorrhiza injection, and includes the following raw materials: 1-3 parts of salvia miltiorrhiza extract, 1-3.5 parts of dalbergia odorifera extract, 12-18 parts of glucose solution, 4-8 parts of glycine, 0.05 part of salvianolic acid A, and 0.04-0.06 part of salvianolic acid B.

[0056] Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A Xiangdan injection preparation device, characterized in that: The invention comprises a dispensing cylinder (1), wherein a partition (7) is fixed in the middle between the inner walls of the dispensing cylinder (1), a plurality of cooling flow diversion components are arranged at equal intervals at the bottom of the partition (7), a cylindrical cavity (14) is opened at the bottom of the partition (7), a plurality of reciprocating cavities (23) connected to the cooling flow diversion components are opened at equal intervals at the top of the partition (7), a filtering component is arranged inside the plurality of reciprocating cavities (23), a cleaning component is arranged at the opening of the plurality of reciprocating cavities (23) at the top of the partition (7), a conical groove (40) is opened in the middle of the top of the partition (7), and a sewage discharge component is arranged inside the conical groove (40); The inner bottom surface of the dispensing barrel (1) is provided with a plurality of exhaust ports (4) equidistantly arranged in the circumferential direction near the edge of the outer surface; the top of the dispensing barrel (1) is connected to two injection pipes (3); a flange ring (2) is fixed to the outer surface of the dispensing barrel (1) near the top edge; a bottom cover (5) is arranged in the middle of the bottom of the dispensing barrel (1); a bracket (19) is fixed between the inner walls of the cylindrical cavity (14); a stepping motor (18) is fixed on the bracket (19); a driving disk (17) is fixed to the output end of the stepping motor (18); the top of the driving disk (17) is inclined and is located inside the cylindrical cavity (14).

2. A Xiangdan injection preparation device according to claim 1, characterized in that: The cooling diversion component includes a spiral tube (6), the top of which is fixed to the bottom of the partition (7), the bottom of which passes through to the bottom of the bottom cover (5), the inner bottom surface of the reciprocating cavity (23) is provided with a drainage channel (26), one end of which is connected to the top of the spiral tube (6), the interior of the partition (7) is provided with an annular cavity (13), the outer surface of the dispensing cylinder (1) is provided with an air supply pipe (12), one end of which is connected to the interior of the annular cavity (13), the inner wall of the cylindrical cavity (14) is provided with an annular groove (15), the top of which is connected to the bottom of the annular cavity (13).

3. A Xiangdan injection preparation device according to claim 2, characterized in that: A limit ring (16) is slidably arranged inside the annular groove (15), the inner wall of the limit ring (16) is fixed to the outer surface of the driving disk (17), a through hole (41) is provided at the top of the limit ring (16) near one side edge and extends to the bottom, the bottom of the partition (7) is located on one side of the spiral tube (6) and is fixed with a nozzle (42), the top of the nozzle (42) is connected to the inner bottom surface of the annular groove (15), the bottom of the partition (7) is located on one side of the nozzle (42) and is obliquely fixed with a guide plate (20), the bottom of the guide plate (20) obliquely extends toward one side of the spiral tube (6).

4. A Xiangdan injection preparation device according to claim 3, characterized in that: The filter assembly comprises a filter cartridge (27), the filter cartridge (27) being slidably disposed between the inner walls of a reciprocating chamber (23), a fixed tube (24) being installed on the inner bottom surface of the reciprocating chamber (23), the bottom of the fixed tube (24) being communicated with a drainage channel (26), the top of the fixed tube (24) being closed, and the top of the fixed tube (24) slidingly penetrates into the interior of the filter cartridge (27), and a plurality of leaking openings (25) penetrating into the interior are equidistantly provided on the outer surface of the fixed tube (24) near the bottom edge along the circumferential direction.

5. A Xiangdan injection preparation device according to claim 4, characterized in that: A protective plate (32) is fixed between the inner walls of the dispensing cylinder (1) and located above the partition (7); the top of the filter cartridge (27) slides through the top of the protective plate (32); a plurality of support rods (9) are fixed to the top of the protective plate (32) at equal intervals in the circumferential direction of the filter cartridge (27); a circular plate (8) is fixed between the tops of the plurality of support rods (9); the circular plate (8) is located directly above the filter cartridge (27); a return spring (10) is fixed between the bottom of the circular plate (8) and the top of the filter cartridge (27); filter screens (28) are provided at the top edges of the inner walls on both sides of the filter cartridge (27); a gap is provided between the bottom of the protective plate (32) and the top of the partition (7); and the outer surface of the filter cartridge (27) has a threaded line.

6. The Xiangdan injection preparation device according to claim 5, characterized in that: A side opening (21) penetrating into the interior of the cylindrical cavity (14) is provided on one side of the reciprocating cavity (23); a shift plate (22) is fixed to the outer surface of one side of the filter cartridge (27); the shift plate (22) is slidably fitted with inner walls on both sides of the side opening (21); one end of the shift plate (22) extends into the interior of the cylindrical cavity (14) and fits with the inclined portion of the top of the driving disc (17).

7. The Xiangdan injection preparation device according to claim 6, characterized in that: The cleaning assembly comprises a fixing ring (29), wherein the fixing ring (29) is fixed to the top of the partition (7), the top of the fixing ring (29) is fixed to the bottom of the protective plate (32), the filter cartridge (27) is located on the inner side of the fixing ring (29), a rotating ring (30) is rotatably arranged between the inner walls of the fixing ring (29), a plurality of brush strips (31) are fixed to the inner wall of the rotating ring (30), the inner side of the brush strips (31) is in contact with the outer surface of the filter cartridge (27), an internal threaded ring (33) is fixed to the bottom of the rotating ring (30), and the inner wall of the internal threaded ring (33) is threadedly connected to the outer surface of the filter cartridge (27).

8. The Xiangdan injection preparation device according to claim 7, characterized in that: The sewage discharge assembly comprises a spiral blade rod (39), a conical groove (40) is provided at the middle of the top of the partition (7), the spiral blade rod (39) is rotatably connected to the inner bottom surface of the conical groove (40), a convex plate (34) is fixed to the inner top surface of the cylindrical cavity (14), a conveying cavity (35) is provided inside the convex plate (34), a conveying disk (36) is rotatably arranged between the inner walls of the conveying cavity (35), a storage groove (37) is provided at the top of the conveying disk (36) near one side edge and extends to the bottom, and the conical groove The inner bottom surface of (40) is provided with a groove (38) near one side edge that penetrates into the interior of the conveying chamber (35); the bottom of the spiral blade rod (39) is fixed to the conveying disk (36); the bottom of the conveying disk (36) penetrates into the interior of the cylindrical cavity (14) and is fixed to the driving disk (17); the bottom of the convex disk (34) is fixed with a drain pipe (11) near one side edge; one end of the drain pipe (11) penetrates into the interior of the conveying chamber (35), and the other end of the drain pipe (11) penetrates to the outside of the filling cylinder (1).

9. A Xiangdan injection preparation process, based on a Xiangdan injection preparation device as claimed in any one of claims 1 to 8, characterized in that: The following steps are involved: Step S1: injecting a mixed solution containing salvia miltiorrhiza extract, dalbergia odorifera extract, glucose solution, glycine, salvianolic acid A and salvianolic acid B into the interior of the dispensing cylinder (1) through the injection pipe (3). At this time, the mixed solution is located above the protective plate (32) in the interior of the dispensing cylinder (1). Then, the stepping motor (18) is started to drive the filtering components to work in sequence, so that the mixed solution can be intermittently discharged into the interior of the cooling shunt component in small batches for cooling. While driving the filtering component to work, the cleaning component is also driven to remove impurities filtered by the filtering component, and the sewage discharge component is driven to discharge impurities removed by the cleaning component. Step S2: When the filter assembly is working, the stepper motor (18) drives the driving disc (17) to rotate. During the rotation process, the inclined surface of the top of the driving disc (17) is in contact with one end of the paddle plate (22), so the paddle plate (22) is driven to move up and down, thereby driving the filter cartridge (27) to move up and down. During the upward movement of the filter cartridge (27), when the filter screen (28) rises above the protective plate (32), the mixed solution above the protective plate (32) can be filtered through the filter screen (28). The mixed solution flows into the interior of the filter cartridge (27), and then, during the process of the filter cartridge (27) descending, since the inner wall of the filter cartridge (27) and the inner wall of the reciprocating cavity (23) are in contact with each other, the mixed solution does not flow into the interior of the reciprocating cavity (23) in the filter cartridge (27), until the filter cartridge (27) descends to the inner bottom surface of the reciprocating cavity (23), causing the leakage port (25) on the fixed tube (24) to slide into the interior of the filter cartridge (27), at which time the mixed liquid in the filter cartridge (27) can flow into the drainage channel (26) from the leakage port (25); Step S3: When the cleaning component is working, when the filter cartridge (27) moves up and down, since the outer surface of the filter cartridge (27) is threadedly connected to the internal thread ring (33), the internal thread ring (33) is driven to rotate, thereby driving the rotating ring (30) to drive the brush bar (31) to clean the outer surface of the filter cartridge (27), and the dirty liquid generated after cleaning will be retained in the gap between the top of the partition (7) and the bottom of the protective plate (32); Step S4: When the sewage discharge assembly is working, when the driving disc (17) rotates, it will also synchronously drive the conveying disc (36) and the spiral blade rod (39) to rotate. The rotation of the spiral blade rod (39) can gather the liquid in the gap between the top of the partition (7) and the bottom of the protective plate (32) to the middle part, so as to facilitate subsequent discharge. When the conveying disc (36) rotates, when the storage groove (37) on the conveying disc (36) rotates to the bottom of the groove (38), the dirty liquid inside the groove (38) and the conical groove (40) can flow into the storage groove (37) for storage. When the storage groove (37) slides to the connection part between the sewage pipe (11) and the conveying chamber (35), the dirty solution inside the storage groove (37) can be discharged to the outside through the sewage pipe (11); Step S5: When the cooling and diversion components are working, when the mixed liquid inside the filter cartridge (27) flows from the leakage port (25) into the drainage channel (26), the liquid will flow into the interior of the spiral tube (6) through the drainage channel (26), and while discharging the liquid, the through hole (41) on the limiting ring (16) will rotate to the connection position between the nozzle (42) and the annular groove (15), so that the nozzle (42) and the annular cavity (13) are connected to each other through the through hole (41). At this time, the cold air supplied by the air supply pipe (12) to the interior of the annular cavity (13) can flow to the nozzle (42) through the through hole (41). Under the action of the nozzle (42) and in conjunction with the guide plate (20), the cold air can flow evenly to the spiral tube (6) to cool the solution inside the spiral tube (6).

10. A Xiangdan injection, which is prepared by the Xiangdan injection preparation process as claimed in claim 9, characterized in that: The invention comprises the following raw materials: 1-3 parts of salvia miltiorrhiza extract, 1-3.5 parts of dalbergia odorifera extract, 12-18 parts of glucose solution, 4-8 parts of glycine, 0.05 parts of salvianolic acid A and 0.04-0.06 parts of salvianolic acid B.

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