Traditional Chinese medicine formula of dark plum and ginseng soup as well as preparation method and application thereof

Wumei Ginseng Decoction prepared by scientifically combining multiple medicinal and food homologous substances has solved health problems such as kidney qi deficiency and qi and blood dissonance, achieved significant conditioning effect and safety, and is suitable for long-term drinking.

CN120204313APending Publication Date: 2025-06-27HANGZHOU MINGGE HEALTH MANAGEMENT CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202510330214.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-20
Publication Date
2025-06-27

AI Technical Summary

Technical Problem

The existing technology is difficult to effectively regulate health problems such as kidney qi deficiency, qi and blood disorder, fluid deficiency, and poor essence.

Method used

By scientifically combining medicinal and food homologous substances such as black plum, lotus leaves, tangerine peel, hawthorn, ginseng, wolfberry, mulberry, polygonatum and licorice, Wumei Ginseng Decoction is prepared to achieve the effects of nourishing the middle and nourishing qi, harmonizing the stomach and strengthening the spleen, nourishing the kidneys and strengthening yang, strengthening the kidneys and stopping excretion.

Benefits of technology

Wumei Ginseng Decoction significantly improves health problems such as kidney deficiency and qi and blood discomfort, enhances physical fitness, improves immunity, comprehensively improves the human sub-health state, and is safe and has no toxic side effects, and is suitable for long-term drinking.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

The traditional Chinese medicine formula is prepared from the following raw materials in parts by weight: 20 to 40 parts of fructus mume, 10 to 20 parts of folium nelumbinis, 10 to 20 parts of pericarpium citri reticulatae, 10 to 20 parts of fructus crataegi, 10 to 20 parts of radix ginseng, 20 to 40 parts of fructus lycii, 20 to 40 parts of fructus mori, 20 to 40 parts of rhizoma polygonati and 10 to 20 parts of radix glycyrrhizae. The traditional Chinese medicine composition follows the theory that the kidney is the root of congenital and the spleen is the root of postnatal in the traditional Chinese medicine, and comprehensively recuperates the body through multiple action mechanisms of tonifying middle-Jiao and Qi, harmonizing the stomach and strengthening the spleen, tonifying the kidney and strengthening Yang, reinforcing the kidney and stopping diarrhea and the like.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine prescriptions, especially to the technical field of Wumei Renshen Decoction. Background Art

[0002] With the accelerating pace of modern life, health problems such as deficiency of kidney qi, disharmony of qi and blood, abnormal movement of body fluids due to deficiency, and spermatorrhea due to deficiency have become increasingly prominent, which have become important factors affecting people's quality of life. Traditional Chinese medicine, with its profound theoretical foundation and unique treatment methods, has significant advantages in regulating such problems. According to the classic theory of traditional Chinese medicine, "the kidney is the innate foundation, and the spleen is the acquired foundation", and the harmonious balance of kidney qi and qi and blood is crucial for maintaining human health. Deficiency of kidney qi, disharmony of qi and blood, abnormal movement of body fluids due to deficiency, and spermatorrhea due to deficiency not only affect physical health but may also lead to a series of dysfunctions and diseases. Therefore, it is of great significance to find a safe and effective traditional Chinese medicine prescription to regulate these symptoms.

[0003] Wumei Decoction and Renshen Jianpi Pills, as two traditional Chinese medicine prescriptions with a long history, each contain rich treatment wisdom and clinical value. In order to more precisely meet the health needs of modern people, the scientific research team, based on in-depth research on traditional prescriptions, through fine addition and subtraction of prescriptions, ingenious pharmacological integration, scientific improvement and innovation, finally developed the new traditional Chinese medicine prescription of Wumei Renshen Decoction. Wumei Renshen Decoction not only inherits the essence of traditional prescriptions but also significantly improves in terms of pertinence, effectiveness and applicability, providing a more effective solution for health problems such as deficiency of kidney qi and disharmony of qi and blood faced by modern people. Summary of the Invention

[0004] The purpose of the present invention is to solve the problems in the prior art and propose a traditional Chinese medicine prescription of Wumei Renshen Decoction for regulating deficiency of kidney qi, disharmony of qi and blood, abnormal movement of body fluids due to deficiency, and spermatorrhea due to deficiency. This prescription, through scientific compatibility of a variety of substances homologous to medicine and food, achieves the effects of replenishing middle qi, regulating the stomach and strengthening the spleen, tonifying kidney yang, and arresting seminal emission.

[0005] To achieve the above purpose, the present invention proposes a traditional Chinese medicine prescription of Wumei Renshen Decoction, which is composed of the following raw materials in parts by weight: 20 - 40 parts of smoked plum, 10 - 20 parts of lotus leaf, 10 - 20 parts of dried tangerine peel, 10 - 20 parts of hawthorn, 10 - 20 parts of ginseng, 20 - 40 parts of wolfberry fruit, 20 - 40 parts of mulberry, 20 - 40 parts of polygonatum, and 10 - 20 parts of licorice.

[0006] Preferably, it is composed of the following raw materials in parts by weight: 30 parts of smoked plum, 15 parts of lotus leaf, 15 parts of dried tangerine peel, 15 parts of hawthorn, 15 parts of ginseng, 30 parts of wolfberry fruit, 30 parts of mulberry, 30 parts of polygonatum, and 15 parts of licorice.

[0007] Preferably, it further includes a flavoring agent.

[0008] Preferably, the flavoring agent is one or more of red dates and honey.

[0009] A preparation method of smoked plum and ginseng decoction includes the following steps: S1. Mix the raw materials evenly; S2. Soak in water and then decoct twice; S3. Combine the decoction liquids and filter to remove residues.

[0010] Preferably, in S2, the soaking time is 30 minutes to 1 hour.

[0011] Preferably, in S2, when decocting, keep simmering for 30 minutes after each boiling.

[0012] Preferably, it further includes S4. Add an appropriate amount of flavoring agent.

[0013] Smoked plum: sour in taste, neutral in nature, attributing to the liver, spleen, lung and large intestine meridians, having the effects of astringing the lung, astringing the intestine, promoting the production of body fluid and expelling roundworms.

[0014] Lotus leaf: bitter in taste, neutral in nature, attributing to the liver, spleen and stomach meridians, capable of clearing summer heat and promoting diuresis, ascending the clear yang, cooling blood and stopping bleeding.

[0015] Dried tangerine peel: bitter and pungent in taste, warm in nature, attributing to the lung and spleen meridians, able to regulate qi and strengthen the spleen, dry dampness and resolve phlegm.

[0016] Hawthorn: sour and sweet in taste, slightly warm in nature, attributing to the spleen, stomach and liver meridians, capable of promoting digestion and strengthening the stomach, promoting qi circulation and removing stasis, and reducing turbidity and lipid.

[0017] Ginseng: sweet and slightly bitter in taste, neutral in nature, attributing to the spleen and lung meridians, having the effects of replenishing qi, promoting the production of body fluid and quenching thirst.

[0018] Wolfberry fruit: sweet in taste, neutral in nature, attributing to the liver and kidney meridians, able to nourish the liver and kidney, benefit essence and improve eyesight.

[0019] Mulberry: sweet and sour in taste, cold in nature, attributing to the heart, liver and kidney meridians, capable of nourishing yin and promoting blood circulation, promoting the production of body fluid and moistening dryness.

[0020] Polygonatum sibiricum: sweet in taste, neutral in nature, attributing to the spleen, lung and kidney meridians, having the effects of replenishing qi and nourishing yin, strengthening the spleen, moistening the lung and tonifying the kidney.

[0021] Licorice root: sweet in taste, neutral in nature, attributing to the heart, lung, spleen and stomach meridians, able to invigorate the spleen and replenish qi, clear heat and detoxify, resolve phlegm and relieve cough, relieve spasm and pain, and harmonize various herbs.

[0022] In the formula of the present invention, smoked plum is used as the monarch drug to achieve the effects of astringing the lung and intestine, promoting the production of body fluid and expelling roundworms; lotus leaf, dried tangerine peel and hawthorn are used as the ministerial drugs to assist smoked plum in regulating qi and blood, and harmonizing the stomach and strengthening the spleen; ginseng, wolfberry fruit, mulberry and polygonatum sibiricum are used as the adjuvant drugs to jointly play the roles of tonifying the kidney and strengthening yang, and consolidating the kidney and stopping diarrhea; licorice root is used as the guiding drug to harmonize various herbs and enhance the overall medicinal effect.

[0023] The formula of Wumei Renshen Decoction follows the theory of traditional Chinese medicine that "the kidney is the foundation of congenital constitution, and the spleen is the foundation of acquired constitution". Through various mechanisms such as replenishing qi and benefiting the middle energizer, regulating the stomach and strengthening the spleen, tonifying the kidney and strengthening yang, and consolidating the kidney to stop diarrhea, it comprehensively nourishes the body. The sour taste of wumei can astringe the lung qi and astringe the intestines; the effect of lotus leaf in clearing summer heat and promoting diuresis helps regulate the internal dampness; the function of tangerine peel in regulating qi and strengthening the spleen can improve the spleen and stomach function; the effect of hawthorn in promoting digestion and strengthening the stomach can relieve problems such as indigestion; the effect of ginseng in replenishing qi and promoting fluid production helps improve the overall physical fitness; the effect of wolfberry fruit in nourishing the liver and kidney can enhance the kidney function; the effect of mulberry in nourishing yin and enriching blood can improve the symptoms of yin deficiency; the effect of polygonatum in replenishing qi and nourishing yin helps regulate yin and yang; and licorice is the key ingredient for coordinating various herbs to ensure the synergistic effect of the whole formula.

[0024] Advantages of the present invention: 1. Comprehensively nourish the body: Following the theory of traditional Chinese medicine that "the kidney is the foundation of congenital constitution, and the spleen is the foundation of acquired constitution", through various mechanisms such as replenishing qi and benefiting the middle energizer, regulating the stomach and strengthening the spleen, tonifying the kidney and strengthening yang, and consolidating the kidney to stop diarrhea, it comprehensively nourishes the body; 2. Safe and without toxic side effects: The raw materials in the formula are all substances that are both food and medicine, safe and without toxic side effects, and suitable for long-term drinking; 3. Significantly improve symptoms: It has a significant conditioning effect on health problems such as kidney qi deficiency and disharmony of qi and blood. Long-term drinking can enhance physical fitness, improve immunity, and improve the sub-healthy state of the human body; 4. Simple preparation method: The preparation method is simple, easy to use, and suitable for a wide range of people. Detailed implementation manners

[0025] Example 1: Take 30 g of wumei, 15 g of lotus leaf, 15 g of tangerine peel, 15 g of hawthorn, 15 g of ginseng, 30 g of wolfberry fruit, 30 g of mulberry, 30 g of polygonatum, and 15 g of licorice. After mixing evenly, add 1000 ml of water and soak for 30 minutes to 1 hour, decoct twice, each time boil and then simmer for 30 minutes to 1 hour, combine the decoction and filter to remove the residue, add an appropriate amount of honey or red dates for seasoning and then it can be drunk, 1 - 2 times a day, appropriate amount each time.

[0026] Example 2: The raw material composition is: 20 parts of wumei, 10 parts of lotus leaf, 10 parts of tangerine peel, 10 parts of hawthorn, 10 parts of ginseng, 20 parts of wolfberry fruit, 20 parts of mulberry, 20 parts of polygonatum, and 10 parts of licorice.

[0027] Others are the same as Example 1.

[0028] Example 3: The raw material composition is: 40 parts of wumei, 20 parts of lotus leaf, 20 parts of tangerine peel, 20 parts of hawthorn, 20 parts of ginseng, 40 parts of wolfberry fruit, 40 parts of mulberry, 40 parts of polygonatum, and 20 parts of licorice.

[0029] The others are the same as in Example 1.

[0030] Example 4: The raw material composition is as follows: 20 g of smoked plum, 15 g of lotus leaf, 15 g of dried tangerine peel, 15 g of hawthorn, 20 g of ginseng, 40 g of wolfberry fruit, 30 g of mulberry, 40 g of polygonatum, and 15 g of licorice.

[0031] The others are the same as in Example 1.

[0032] Example 5: The raw material composition is as follows: 40 g of smoked plum, 15 g of lotus leaf, 15 g of dried tangerine peel, 15 g of hawthorn, 10 g of ginseng, 30 g of wolfberry fruit, 30 g of mulberry, 20 g of polygonatum, and 15 g of licorice.

[0033] The others are the same as in Example 1.

[0034] Example 6: The raw material composition is as follows: 30 g of smoked plum, 15 g of lotus leaf, 20 g of dried tangerine peel, 20 g of hawthorn, 20 g of ginseng, 20 g of wolfberry fruit, 40 g of mulberry, 20 g of polygonatum, and 10 g of licorice.

[0035] The others are the same as in Example 1.

[0036] Example 7: The raw material composition is as follows: 30 parts of smoked plum, 15 parts of lotus leaf, 15 parts of dried tangerine peel, 12 parts of hawthorn, 18 parts of ginseng, 35 parts of wolfberry fruit, 25 parts of mulberry, 30 parts of polygonatum, and 16 parts of licorice.

[0037] The others are the same as in Example 1.

[0038] Example 7: The raw material composition is as follows: 25 parts of smoked plum, 18 parts of lotus leaf, 13 parts of dried tangerine peel, 16 parts of hawthorn, 14 parts of ginseng, 28 parts of wolfberry fruit, 32 parts of mulberry, 25 parts of polygonatum, and 12 parts of licorice.

[0039] The others are the same as in Example 1.

[0040] Example 8: The raw material composition is as follows: 35 parts of smoked plum, 12 parts of lotus leaf, 17 parts of dried tangerine peel, 14 parts of hawthorn, 17 parts of ginseng, 30 parts of wolfberry fruit, 38 parts of mulberry, 35 parts of polygonatum, and 18 parts of licorice The others are the same as in Example 1.

[0041] Example 9: The raw material composition is as follows: 28 parts of smoked plum, 16 parts of lotus leaf, 14 parts of dried tangerine peel, 13 parts of hawthorn, 15 parts of ginseng, 32 parts of wolfberry fruit, 28 parts of mulberry, 28 parts of polygonatum, and 14 parts of licorice.

[0042] The others are the same as in Example 1.

[0043] Example 10: The raw material composition is as follows: 32 parts of smoked plum, 17 parts of lotus leaf, 16 parts of dried tangerine peel, 17 parts of hawthorn, 16 parts of ginseng, 36 parts of wolfberry fruit, 30 parts of mulberry, 32 parts of polygonatum, and 15 parts of licorice.

[0044] Other aspects are the same as in Example 1.

[0045] Example 11: The raw material composition is as follows: 26 parts of smoked plum, 19 parts of lotus leaf, 18 parts of dried tangerine peel, 18 parts of hawthorn, 19 parts of ginseng, 26 parts of wolfberry fruit, 35 parts of mulberry, 26 parts of polygonatum, and 17 parts of licorice.

[0046] Other aspects are the same as in Example 1.

[0047] The traditional Chinese medicine formula of the smoked plum and ginseng decoction of the present invention has carefully selected and scientifically combined a variety of substances that are both medicine and food, ensuring its safety and non-toxic side effects; the formula is scientific, the design is rigorous, integrating traditional Chinese medicine theory and modern health needs, aiming to achieve multiple effects such as invigorating the middle qi, regulating the stomach and strengthening the spleen, tonifying the kidney and strengthening yang, and consolidating the kidney and stopping diarrhea.

[0048] For the common health problems of modern people such as kidney qi deficiency, disharmony of qi and blood, abnormal movement of body fluids due to deficiency, and thin and unstable essence, the smoked plum and ginseng decoction has shown significant conditioning effects; at the same time, the preparation method of the smoked plum and ginseng decoction is simple and easy to use, suitable for a wide range of people; long-term moderate drinking can not only effectively relieve related symptoms such as soreness and weakness in the waist and knees, frequent nocturia, pale complexion, irregular menstruation, and fatigue, but also enhance physical fitness, improve immunity, comprehensively improve the sub-healthy state of the human body, and promote the balance of physical and mental health.

[0049] Clinical verification: To verify the effectiveness of the traditional Chinese medicine formula of the smoked plum and ginseng decoction of the present invention, we conducted a prospective, randomized, double-blind, placebo-controlled clinical trial in 2024. After months of follow-up observation and treatment, the results showed that the total effective rate was as high as 86%, fully proving the significant curative effect of the smoked plum and ginseng decoction in practical applications; most patients had obvious relief or disappearance of related symptoms after taking it, and the quality of life was significantly improved; the following are the detailed clinical experimental data and result analysis: 1. Trial design Research subjects: 100 patients who met the diagnostic criteria of kidney qi deficiency, disharmony of qi and blood, abnormal movement of body fluids due to deficiency, and spermatorrhea due to deficiency from January 2024 to October 2024 were selected as research subjects.

[0050] Inclusion criteria: Aged 18 - 65 years old, without serious organic lesions in the heart, brain, liver, kidneys, etc., voluntarily participated in this study and signed an informed consent form.

[0051] Exclusion criteria: Comorbid with other serious diseases, allergic to the components of the prescription, or currently using other medications or therapies that may affect the efficacy.

[0052] Grouping method: The patients were divided into the experimental group and the control group using the random number table method, with 50 cases in each group.

[0053] 2. Treatment methods Experimental group: Given Wumei Renshen Decoction, 1 dose per day, taken in 2 divided doses, continuously for 3 months.

[0054] Control group: Given placebo (a substance with similar composition to Wumei Renshen Decoction but without pharmacological activity), taken in the same way as the experimental group.

[0055] 3. Observation indicators Main efficacy indicator: TCM syndrome score, including the improvement of symptoms such as soreness and weakness in the waist and knees, frequent nocturia, pale complexion, irregular menstruation, fatigue, etc.

[0056] Secondary efficacy indicator: Quality of life score, evaluated using the SF-36 Quality of Life Scale. This scale includes 8 dimensions, namely physical function (PF), role physical (RP), bodily pain (BP), general health (GH), vitality (VT), social function (SF), role emotional (RE), and mental health (MH). The score range for each dimension is 0 - 100 points, and the higher the score, the better the quality of life.

[0057] Safety indicator: Laboratory tests such as blood routine, urine routine, liver and kidney function, etc., and the incidence of adverse reactions.

[0058] 4. Evaluation method for quality of life score The quality of life score was evaluated using the SF-36 Quality of Life Scale; before the start of the trial and after the end of treatment, professional medical staff conducted face-to-face interviews with the patients and filled in the scale according to the patients' answers; each dimension in the scale contains several questions, each question has preset options, and the patients choose the most appropriate answer according to their actual situation; finally, according to the scoring rules of the scale, the score of each dimension was calculated and the total score was obtained; the higher the total score, the better the quality of life of the patient.

[0059] 5. Statistical methods SPSS 25.0 software was used for statistical analysis, and the data were expressed as mean ± standard deviation (s). Independent t-test or Mann-Whitney U test was used for comparison between the two groups, and paired t-test or paired rank sum test was used for comparison before and after within the group. P < 0.05 was considered statistically significant.

[0060] 6. Results Traditional Chinese Medicine (TCM) syndrome score: Before treatment, there was no significant difference in the TCM syndrome scores between the two groups (P > 0.05); after treatment, the TCM syndrome score of the experimental group was significantly lower than that of the control group (P < 0.01), and the difference in the experimental group before and after treatment was also statistically significant (P < 0.01).

[0061] Quality of life score: Before treatment, there was no significant difference in the quality of life scores between the two groups (P > 0.05); after treatment, the quality of life score of the experimental group was significantly higher than that of the control group (P < 0.01), and the difference in the experimental group before and after treatment was also statistically significant (P < 0.01); specifically, the scores of the experimental group in 8 dimensions, including physical function, physical role, bodily pain, general health, vitality, social function, emotional role, and mental health, were all significantly higher than those of the control group (P < 0.05 or P < 0.01).

[0062] Safety indicators: No abnormal changes were found in the laboratory tests of blood routine, urine routine, liver and kidney functions, etc. in both groups, and the incidence of adverse reactions was relatively low, and no serious adverse reactions occurred.

[0063] 7. Conclusion Through this clinical trial, we verified the significant curative effect of the traditional Chinese medicine formula of Wumei Renshen Decoction in regulating health problems such as kidney qi deficiency and disharmony of qi and blood. This formula is safe, non-toxic, has a simple preparation method and is easy to use, suitable for a wide range of people; long-term moderate consumption can not only effectively relieve related symptoms, but also enhance physical fitness, improve immunity, and comprehensively improve the sub-healthy state of the human body.

[0064] 8. Analysis of typical cases Case 1: Mr. Zhang, 45 years old, due to long-term high work pressure, suffered from soreness and weakness in the waist and knees and frequent nocturia. After continuously taking Wumei Renshen Decoction for 3 months, the symptoms of soreness and weakness in the waist and knees were significantly relieved, the frequency of nocturia decreased significantly, and the quality of life was significantly improved.

[0065] Case 2: Ms. Li, 38 years old, had long-term pale complexion, irregular menstruation, and often felt fatigued. After 3 months of conditioning with Wumei Renshen Decoction, her complexion became rosy, her menstruation returned to normal, she had sufficient energy, and her overall health condition was significantly improved, and the quality of life was greatly improved.

[0066] The above embodiments are illustrative of the present invention, not limiting the present invention. Any simply transformed scheme of the present invention belongs to the protection scope of the present invention.

Claims

1. A Chinese medicine formula of Wumei Renshen Decoction, characterized in that: The invention is composed of the following raw materials in parts by weight: 20-40 parts of black plum, 10-20 parts of lotus leaf, 10-20 parts of tangerine peel, 10-20 parts of hawthorn, 10-20 parts of ginseng, 20-40 parts of wolfberry, 20-40 parts of mulberry, 20-40 parts of polygonatum and 10-20 parts of liquorice.

2. The Chinese medicine formula of Wumei Renshen Decoction as claimed in claim 1, characterized in that: The invention is composed of the following raw materials in parts by weight: 30 parts of black plum, 15 parts of lotus leaf, 15 parts of tangerine peel, 15 parts of hawthorn, 15 parts of ginseng, 30 parts of wolfberry, 30 parts of mulberry, 30 parts of polygonatum and 15 parts of liquorice.

3. The Chinese medicine formula of Wumei Renshen Decoction as claimed in claim 1, characterized in that: Flavorings are also included.

4. The Chinese medicine formula of Wumei Renshen Decoction as claimed in claim 3, characterized in that: The flavoring agent is one or more of red dates and honey.

5. A method for preparing black plum and ginseng soup, characterized in that: The following steps are involved: S1. Mix the raw materials according to any one of claims 1 to 2 uniformly; S2, soak in water and boil twice; S3. Combine the decoctions and filter to remove the residue.

6. The method for preparing the dark plum and ginseng soup as claimed in claim 5, characterized in that: In S2, the soaking time is 30 minutes to 1 hour.

7. The method for preparing the dark plum and ginseng soup as claimed in claim 5, characterized in that: In S2, when decocting, keep decocting on low heat for 30 minutes after each boiling.

8. The method for preparing the dark plum and ginseng soup as claimed in claim 5, characterized in that: The method further comprises S4, adding appropriate amount of seasoning.

9. Use of the black plum and ginseng soup as claimed in any one of claims 1 to 4 in tea beverages.