Radiation delivery method and device and storage medium

Abstract

The invention relates to a radiation delivery method and device and a storage medium. A first four-dimensional FBCT image of an object is acquired, a plan image is generated according to sub-images in the first four-dimensional FBCT image, a radiation delivery plan of the object is generated according to the plan image, and radiation delivery is performed on the object according to the radiation delivery plan. The embodiment of the invention not only can be used for a common radiation delivery plan, but also can be used for a gated radiation delivery plan. During the execution of each step of the method, the object is held on the support device. Therefore, the integrated radiation delivery process is realized by using the preoperative and intraoperative four-dimensional FBCT images, the waiting time from preoperative simulation positioning to intraoperative radiation treatment of an object in the past is shortened, and the problem of long time consumption in the whole radiation delivery process is solved; and moreover, the possibility that the body position of the object moves and the region of interest changes and transfers in the waiting period is eliminated, and the accuracy of radiation delivery is improved.

Description

Technical Field

[0001] This application relates to the field of radiation delivery, and in particular, to a radiation delivery method, apparatus, and storage medium. Background Art

[0002] With the development of the times, the role and status of radiation delivery (such as radiotherapy, radiation processing, radiation flaw detection, etc.) in tumor treatment and industrial applications have become increasingly prominent.

[0003] As an example, in radiotherapy, the current radiation delivery is to determine the delineated area through Computed Tomography (CT) images before surgery, and formulate a treatment plan based on the delineated area. During surgery, the position and movement range of the target area are reflected through four-dimensional Cone beam Computed Tomography (CBCT) or three-dimensional CBCT images to achieve precise radiation delivery.

[0004] Generally, the delineated range is determined through CT images before surgery, and a radiation delivery plan is formulated based on the delineated range. During surgery, the position and movement range of the target area are reflected through four-dimensional CBCT or three-dimensional CBCT images. Compared with four-dimensional FBCT images (i.e., 4D-FBCT (Fan Beam Computed Tomography)), the field of view of four-dimensional CBCT images is smaller, and the image quality is also inferior to that of four-dimensional FBCT. Moreover, when scanning for the same time length, the scanning time of four-dimensional CBCT images is longer, and there are requirements for the starting angle of the scan. Also, four-dimensional CBCT images cannot be used for generating radiation delivery plans.

[0005] Through the above analysis, on the one hand, the field of view of four-dimensional CBCT images is smaller and the image quality is poor. In cases where the movement range of the target area is large or the volume of the target area is large, it may be difficult to accurately obtain the position and movement range of the target area from four-dimensional CBCT images.

[0006] On the other hand, when scanning for the same time length, the scanning time of four-dimensional CBCT images is longer, which will lead to a long time for the entire radiation delivery, increase the possibility of patient movement, and thus result in a decrease in the accuracy of radiation delivery.

[0007] Thirdly, dose calculation cannot be performed on 4D CBCT images. That is, the patient needs to determine the delineation range through CT images before surgery and formulate a radiation delivery plan based on the delineation range. During surgery, the position and movement range of the target area are obtained through 4D CBCT images, which cannot be used as planning images to generate a radiation delivery plan. The preoperative simulation positioning and intraoperative radiation delivery are two independent parts, and an integrated radiation delivery process cannot be achieved. Since there is a time interval between formulating the radiation delivery plan before surgery and intraoperative radiation delivery, if it is found during surgery through 4D CBCT images that the position and movement range of the target area are significantly different from the delineation range determined through CT images before surgery, it is necessary to re-obtain CT images to formulate a radiation delivery plan, and the entire radiation delivery process is cumbersome and time-consuming. Summary of the Invention

[0008] Based on this, in view of the above technical problems, it is necessary to provide a radiation delivery method, device, and storage medium that can reduce the radiation delivery duration and improve the accuracy of radiation delivery.

[0009] First aspect, the present application provides a radiation delivery method, including:

[0010] Obtain a first 4D FBCT image of an object;

[0011] Generate a planning image based on sub-images in the first 4D FBCT image;

[0012] Generate a radiation delivery plan for the object based on the planning image;

[0013] Perform radiation delivery on the object according to the radiation delivery plan.

[0014] In one embodiment, the generating a planning image based on sub-images in the first 4D FBCT image includes:

[0015] Obtain the motion information of the region of interest in the first 4D FBCT image;

[0016] If the motion information meets the preset motion information, generate a planning image based on sub-images in the first 4D FBCT image.

[0017] In one embodiment, the generating a radiation delivery plan for the object based on the planning image includes:

[0018] When the movement range of the region of interest in the first 4D FBCT image is within the delineation range on the planning image, generate a radiation delivery plan for the object; the motion information includes the movement range.

[0019] In one embodiment, the method further includes:

[0020] Generate a density projection image based on the sub-images;

[0021] Register the density projection image and the planning image to obtain a registered image;

[0022] Determine whether the motion range is within the delineated range based on the registered image.

[0023] In one embodiment, the radiating the object according to the radiation delivery plan includes:

[0024] Obtain a second four-dimensional FBCT image of the object;

[0025] When the motion range of the region of interest in the second four-dimensional FBCT image is within the delineated range on the planning image, radiate the object according to the radiation delivery plan.

[0026] In one embodiment, the first four-dimensional FBCT image is obtained based on first motion information, the second four-dimensional FBCT image is obtained based on second motion information, and the radiating the object according to the radiation delivery plan includes:

[0027] When the difference between the first motion information and the second motion information is within a difference range, radiate the object according to the radiation delivery plan.

[0028] In one embodiment, the object remains on the support device during each step of performing the method.

[0029] In one embodiment, the step of obtaining the first four-dimensional FBCT image of the object and the step of radiating the object according to the radiation delivery plan are performed by the same radiation delivery device.

[0030] In a second aspect, the present application also provides a radiation delivery device, including:

[0031] An acquisition unit for acquiring a first four-dimensional FBCT image of an object;

[0032] A calculation unit for generating a planning image based on sub-images in the first four-dimensional FBCT image and generating a radiation delivery plan for the object according to the planning image;

[0033] An execution unit for radiating the object according to the radiation delivery plan.

[0034] In a third aspect, the present application also provides a computer device, including a memory and a processor. The memory stores a computer program, and when the processor executes the computer program, the following steps are implemented:

[0035] Obtain a first four-dimensional FBCT image of an object;

[0036] Generate a plan image based on sub-images in the first four-dimensional FBCT image;

[0037] Generate a radiation delivery plan for the object according to the plan image;

[0038] Perform radiation delivery on the object according to the radiation delivery plan.

[0039] In a fourth aspect, the present application also provides a computer-readable storage medium, on which a computer program is stored. When the computer program is executed by a processor, the following steps are implemented:

[0040] Obtain a first four-dimensional FBCT image of an object;

[0041] Generate a plan image based on sub-images in the first four-dimensional FBCT image;

[0042] Generate a radiation delivery plan for the object according to the plan image;

[0043] Perform radiation delivery on the object according to the radiation delivery plan.

[0044] In a fifth aspect, the present application also provides a computer program product, including a computer program. When the computer program is executed by a processor, the following steps are implemented:

[0045] Obtain a first four-dimensional FBCT image of an object;

[0046] Generate a plan image based on sub-images in the first four-dimensional FBCT image;

[0047] Generate a radiation delivery plan for the object according to the plan image;

[0048] Perform radiation delivery on the object according to the radiation delivery plan.

[0049] The above-mentioned radiation delivery method, device, and storage medium obtain the first four-dimensional FBCT image of an object, generate a planning image based on the sub-images in the first four-dimensional FBCT image, generate a radiation delivery plan for the object according to the planning image, and thus perform radiation delivery on the object according to the radiation delivery plan. The embodiments of the present application can be used not only for ordinary radiation delivery plans but also for gated radiation delivery plans. During the execution of each step of the above method, the object remains on the support device. Therefore, by using the four-dimensional FBCT images before and during the operation, an integrated radiation delivery process is realized, reducing the waiting time between preoperative simulation positioning and intraoperative radiotherapy in the past, reducing the problem of the long duration of the entire radiation delivery process, and eliminating the possibility of object body position movement, changes, and metastasis of the region of interest during the waiting period, improving the accuracy of radiation delivery. Description of the Drawings

[0050] To more clearly illustrate the technical solutions in the embodiments of the present application or related technologies, the following will briefly introduce the drawings required for use in the description of the embodiments or related technologies. Obviously, the drawings in the following description are only some embodiments of the present application. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings.

[0051] Figure 1 It is an application environment diagram of the radiation delivery method in an embodiment;

[0052] Figure 2 It is a flowchart of the radiation delivery method in an embodiment;

[0053] Figure 3 It is a flowchart of the planning image generation method in an embodiment;

[0054] Figure 4 It is a flowchart of the motion range and delineation range judgment method in an embodiment;

[0055] Figure 5 It is a flowchart of the radiation delivery method in another embodiment;

[0056] Figure 6 It is a flowchart of the radiation delivery method in another embodiment;

[0057] Figure 7 It is a structural block diagram of the radiation delivery device in an embodiment;

[0058] Figure 8 It is an internal structure diagram of a computer device in an embodiment. Detailed Embodiments

[0059] In order to make the objectives, technical solutions and advantages of the present application more clearly understood, the present application will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0060] The radiation delivery method (such as radiotherapy, radiation processing, radiation flaw detection, etc.) provided by the embodiments of the present application can be applied to an application environment as Figure 1 shown. Among them, the application environment includes a radiation delivery device, and the radiation delivery device includes a computer device 1, an FBCT device 2, a radiation device 3, and a support device 4. The object is moved to the position corresponding to the FBCT device 2 through the support device 4, and the object is scanned by the FBCT device 2 to obtain a first four-dimensional FBCT image. The computer device 1 acquires the first four-dimensional FBCT image, generates a planned image according to the sub-images in the first four-dimensional FBCT image, and generates a radiation delivery plan for the object according to the planned image. Then, the object is moved to the position corresponding to the radiation device 3 through the support device 4, and the computer device controls the radiation device 3 to perform radiation delivery on the object according to the radiation delivery plan. Optionally, the computer device 1 can be a server, and the server can be implemented by an independent server or a server cluster composed of multiple servers.

[0061] In an exemplary embodiment, as Figure 2 shown, a radiation delivery method is provided. Taking the method applied to the Figure 1 computer device as an example, it includes the following S201 to S203. Among them:

[0062] S201, acquire a first four-dimensional FBCT image of the object.

[0063] Among them, the first four-dimensional FBCT image can obtain the positions of the regions of interest of the object at multiple moments. For example, the first four-dimensional FBCT image includes 3D-CT1 at the first moment, 3D-CT2 at the second moment, 3D-CT3 at the third moment... 3D-CTn at the nth moment, and the specific positions of the regions of interest are acquired on each 3D-CT.

[0064] In this embodiment, the support device is moved to send the object under the FBCT device, and the object is scanned by the Figure 1 FBCT device in it to obtain the raw data of the object, and the raw data is sent to the computer device. The computer device reconstructs the raw data to obtain a first four-dimensional FBCT image. When reconstructing, the computer device can reconstruct based on amplitude or phase, or partially based on amplitude and phase to obtain the first four-dimensional FBCT image.

[0065] S202. Generate a planning image based on the sub-images in the first four-dimensional FBCT image.

[0066] Optionally, the planning image can be a single image or multiple images.

[0067] In this embodiment, when the region of interest (such as the target area or the area around the target area) is not affected by movement (such as movement, contraction, expansion, etc.), that is, for ordinary radiation delivery, the planning image can be directly generated based on all the sub-images in the first four-dimensional FBCT image, or based on some of the sub-images in the first four-dimensional FBCT image. For example, the first four-dimensional FBCT image includes 3D-CT1, 3D-CT2, 3D-CT3, 3D-CT4, 3D-CT5, 3D-CT6, 3D-CT7, 3D-CT8, 3D-CT9, 3D-CT10. The planning image can be generated based on all the sub-images in the first four-dimensional FBCT image, or based on any one of the 3D-CTs.

[0068] When the region of interest is affected by movement, the planning image can be generated based on the sub-images in the first four-dimensional FBCT image where the region of interest appears. For example, the first four-dimensional FBCT image includes 3D-CT1, 3D-CT2, 3D-CT3, 3D-CT4, 3D-CT5, 3D-CT6, 3D-CT7, 3D-CT8, 3D-CT9, 3D-CT10. Due to the influence of breathing, the region of interest does not appear in 3D-CT1, 3D-CT2, 3D-CT6, 3D-CT7, and appears in 3D-CT3, 3D-CT4, 3D-CT5, 3D-CT8, 3D-CT9, 3D-CT10. Then the planning image is generated based on 3D-CT3, 3D-CT4, 3D-CT5, and the corresponding planning image is generated based on 3D-CT8, 3D-CT9, 3D-CT10.

[0069] S203. Generate a radiation delivery plan for the object based on the planning image.

[0070] In this embodiment, based on the information included in the planning image (such as the shape and size of the region of interest; the composition of the surrounding area of the region of interest, etc.), the radiation delivery plan can be determined. As an example, the radiation delivery plan can include one or more of the radiation dose distribution, the area to be radiated, the machine parameters of the radiation delivery device, etc.

[0071] In an exemplary embodiment, a planned image can be contoured to determine the contour range, the planned image can be registered with the corresponding sub-image that generates the planned image, and it can be determined whether the regions of interest are all within the contour range. If all the regions of interest are within the contour range, that is, when the contour range is correct, a radiation delivery plan for the object is generated according to the planned image.

[0072] In another exemplary embodiment, during contouring of the planned image to determine the contour range, a radiation delivery plan for the object is directly generated according to the planned image containing the contour range.

[0073] S204, perform radiation delivery on the object according to the radiation delivery plan.

[0074] In a possible implementation, move the support device to Figure 1 below the radiation device in, and perform radiation delivery on the object according to the radiation delivery plan.

[0075] In another possible implementation, since it takes a certain amount of time to generate the radiation delivery plan, to avoid changes in the object's body position during this process, after generating the radiation delivery plan for the object according to the planned image, a second four-dimensional FBCT image can be obtained, the second four-dimensional FBCT image and the planned image are registered, and if all the regions of interest are within the contour range, radiation delivery is performed on the object according to the radiation delivery plan.

[0076] In the above radiation delivery method, by obtaining the first four-dimensional FBCT image of the object, generating a planned image according to the sub-images in the first four-dimensional FBCT image, generating a radiation delivery plan for the object according to the planned image, and thus performing radiation delivery on the object according to the radiation delivery plan. The embodiments of the present application can be used not only for ordinary radiation delivery plans but also for gated radiation delivery plans. During the execution of each step of the above method, the object remains on the support device. Thus, by using the four-dimensional FBCT images before and during the operation, an integrated radiation delivery process is realized, reducing the waiting time between preoperative simulation positioning and intraoperative radiation therapy in the past, reducing the problem of the long duration of the entire radiation delivery process, and eliminating the possibility of object body position movement, changes and transfers of the regions of interest during the waiting period, improving the accuracy of radiation delivery.

[0077] Figure 3 is a schematic flowchart of a method for generating a planned image in an embodiment. As Figure 3 shown, the embodiments of the present application relate to a possible implementation of how to generate a planned image according to the sub-images in the first four-dimensional FBCT image, including the following steps:

[0078] S301, obtain the motion information of the region of interest in the first four-dimensional FBCT image.

[0079] Optionally, the motion information may be a motion range or a motion trajectory of the region of interest, or a change in shape or volume of the region of interest.

[0080] Optionally, the region of interest may be the lesion tissue of the subject, or may be the organ and / or tissue surrounding the lesion tissue, or may be the lesion tissue and the organ and / or tissue surrounding the lesion tissue, and so on.

[0081] In this embodiment, for target organs such as liver, lung, and pancreas that are greatly affected by respiratory motion, the first four-dimensional FBCT can fully reflect the motion trajectory and range of the target area. Assume that the first four-dimensional FBCT image includes 3D-CT1, 3D-CT2, 3D-CT3, 3D-CT4, 3D-CT5, and 3D-CT6. The motion information of the region of interest can be obtained based on the feature information of the region of interest in each 3D-CT.

[0082] S302: If the motion information satisfies the preset motion information, a planning image is generated according to the sub-image in the first four-dimensional FBCT image.

[0083] In this embodiment, exemplarily, the motion information of the region of interest is a motion range. If the motion range is greater than a preset motion range, a planning image is generated according to a sub-image in the first four-dimensional FBCT image.

[0084] In another exemplary embodiment, the motion information of the region of interest is the volume of the region of interest, and if the volume of the region of interest is greater than a preset volume, a planning image is generated according to a sub-image in the first four-dimensional FBCT image. For example, if a treatment plan has been determined by a CT image before surgery, and it is found through the first four-dimensional FBCT that the target volume is greater than the preset volume, a planning image can be generated using a sub-image in the first four-dimensional FBCT image to facilitate subsequent dose calculation on the planning image and re-optimize the treatment plan.

[0085] In the embodiment of the present application, by acquiring the motion information of the region of interest in the first four-dimensional FBCT image, if the motion information satisfies the preset motion information, a planning image is generated according to the sub-image in the first four-dimensional FBCT image. In the embodiment of the present application, a planning image is generated when the motion information of the region of interest satisfies the preset motion information, providing a basis for subsequent gated radiation delivery.

[0086] In one embodiment, generating a radiation delivery plan for an object according to a planning image includes: generating a radiation delivery plan for the object according to the planning image when a motion range of a region of interest in a first four-dimensional FBCT image is within a delineated range on the planning image; wherein the motion information may include the motion range.

[0087] In this embodiment, a delineation range is determined by delineating on the planning image. A density projection image is determined according to the sub-images that generate the planning image. The density projection image is registered with the planning image to determine whether the regions of interest are all within the delineation range. If all the regions of interest are within the delineation range, a radiotherapy delivery plan for the object is generated according to the planning image.

[0088] In an exemplary embodiment, the planning image is registered one by one with the corresponding sub-images that generate the planning image to determine whether the regions of interest corresponding to each sub-image are all within the delineation range. If all the regions of interest are within the delineation range, that is, when the delineation range is correct, a radiotherapy delivery plan for the object is generated according to the planning image.

[0089] In the embodiments of the present application, when the movement range of the region of interest in the first four-dimensional FBCT image is within the delineation range on the planning image, a radiotherapy delivery plan for the object is generated according to the planning image. In the embodiments of the present application, the first four-dimensional FBCT image has a larger field of view and can show the organ conditions of the object in a larger range. In addition, the scanning time is shorter. By using the first four-dimensional FBCT image, the movement trajectory and movement range of the region of interest of the object can be quickly scanned, so the time consumed is shorter, the treatment time of the patient is shortened, and the possibility of the patient's body position movement is reduced.

[0090] Figure 4 For a flowchart showing the method for judging the movement range and the delineation range in an embodiment, as Figure 4 shown, it includes the following steps:

[0091] S401, generating a density projection image according to the sub-images.

[0092] S402, registering the density projection image and the planning image to obtain a registered image.

[0093] S403, determining whether the movement range is within the delineation range according to the registered image.

[0094] In this embodiment, a first four-dimensional FBCT image is obtained by scanning using an FBCT device. The object is moved to the corresponding position of the radiotherapy device. During this period, a density projection image can be generated according to the corresponding sub-images, and the density projection image and the planning image are registered based on a registration algorithm to obtain a registered image. For example, if the planning image is a planning image generated according to 3D-CT3, 3D-CT4, and 3D-CT5, density projection images are generated according to the corresponding sub-images 3D-CT3, 3D-CT4, and 3D-CT5, and the planning image and the density projection images are registered.

[0095] Determine whether the movement range of the region of interest is within the delineated range based on the registered image. If the movement range of the region of interest is not within the delineated range, the support device can be moved so that the movement range of the region of interest is within the delineated range, thereby implementing the radiation delivery plan.

[0096] In the embodiments of the present application, a density projection image is generated based on the sub-images, the density projection image and the planned image are registered to obtain a registered image, and whether the movement range is within the delineated range is determined based on the registered image, ensuring the stability of the implementation of the radiation delivery plan.

[0097] In one embodiment, radiation delivery to an object is performed according to a radiation delivery plan, including: obtaining a second four-dimensional FBCT image of the object; when the movement range of the region of interest in the second four-dimensional FBCT image is within the delineated range on the planned image, performing radiation delivery to the object according to the radiation delivery plan.

[0098] In this embodiment, in order to avoid the pose of the object changing during the generation of the radiation delivery plan, resulting in the region of interest not being within the delineated range. Before implementing the radiation delivery plan, a second four-dimensional FBCT image of the object is obtained, registered with the planned image, and it is confirmed whether the movement range of the region of interest is within the delineated range, further confirming the delineated range. When the movement range is within the delineated range, radiation delivery to the object is performed according to the radiation delivery plan.

[0099] Similarly, the radiation delivery plan can also be optimized based on the second four-dimensional FBCT image. When the movement range is within the delineated range, radiation delivery to the object is performed according to the radiation delivery plan.

[0100] In a possible implementation manner, after registering the second four-dimensional FBCT image and the planned image and confirming that the movement range is within the delineated range, further, confirmation is performed based on the first respiratory information corresponding to the first four-dimensional FBCT image and the second respiratory information corresponding to the second four-dimensional FBCT image. When the characteristics of the first respiratory information and the second respiratory information are consistent, radiation delivery to the object is performed according to the radiation delivery plan.

[0101] Further, performing radiation delivery to the object according to the radiation delivery plan includes: when the difference between the first respiratory information and the second respiratory information is within the difference range, performing radiation delivery to the object according to the radiation delivery plan.

[0102] In this embodiment, as Figure 5As shown, the object wears a body surface monitoring device to complete the positioning. During the scanning of the object, respiratory information is obtained. Based on the respiratory information and the raw data of the scan, a four-dimensional FBCT image is reconstructed. That is, when the object wears a body surface monitoring device to complete the positioning and the object is scanned to obtain the first four-dimensional FBCT image, the first respiratory information can be obtained based on the body surface monitoring device. Whether gated radiation delivery is required is determined according to the first four-dimensional FBCT image. That is, if the motion information of the region of interest in the first four-dimensional FBCT image meets the preset motion information, gated radiation delivery is required.

[0103] A planning image is generated according to the sub-images in the first four-dimensional FBCT image. When the motion range of the region of interest in the first four-dimensional FBCT image is within the delineated range on the planning image, a radiation delivery plan for the object is generated according to the planning image.

[0104] When the object is scanned to obtain the second four-dimensional FBCT image, the second respiratory information can be obtained based on the body surface monitoring device. Registration is performed according to the second four-dimensional FBCT image and the planning image. When it is confirmed that the motion range of the region of interest in the second four-dimensional FBCT image is within the delineated range, further, the first respiratory information and the second respiratory information are confirmed. When the characteristics of the first respiratory information and the second respiratory information are consistent, or when the difference between the first respiratory information and the second respiratory information is within the difference range, radiation delivery is performed on the object according to the radiation delivery plan. That is, the same set of body surface monitoring devices is used for simulation positioning and subsequent treatment, improving the consistency of simulation positioning and treatment.

[0105] In the embodiments of the present application, by obtaining the second four-dimensional FBCT image of the object, when the motion range of the region of interest in the second four-dimensional FBCT image is within the delineated range on the planning image and the difference between the first respiratory information and the second respiratory information is within the difference range, radiation delivery is performed on the object according to the radiation delivery plan. In the embodiments of the present application, radiation delivery is performed on the object when the motion range in the second four-dimensional FBCT image is within the delineated range on the planning image, improving the accuracy of radiation delivery. Moreover, the first respiratory information and the second respiratory information are compared, improving the consistency of simulation positioning and radiation delivery treatment, and helping to improve the accuracy of radiation delivery.

[0106] In one embodiment, during the execution of the above steps of the method, the object remains on the support device.

[0107] Among them, the support device is used to support the object. For example, in the radiotherapy scenario, the support device can be a support device; in the radiation processing scenario, the support device can be a processing table, etc.

[0108] In this embodiment, as Figure 6As shown, the subject wears a body surface monitoring device to complete the positioning, moves the support device to the position of the FBCT device for scanning to obtain the first four-dimensional FBCT image, and moves the support device to the position of the radiotherapy device. During this period, a planning image is generated based on the sub-images in the first four-dimensional FBCT image, a density projection image is generated based on the corresponding sub-images, the planning image and the density projection image are registered to obtain a registered image, and it is determined whether the motion range of the region of interest is within the delineated range according to the registered image. If the motion range of the region of interest is not within the delineated range, the support device is moved so that the region of interest is within the delineated range, and a radiotherapy delivery plan is generated based on the planning image, and the radiotherapy delivery plan is executed on the subject.

[0109] It can be found that during the whole process from obtaining the first four-dimensional FBCT image to performing radiotherapy delivery on the subject according to the radiotherapy delivery plan, the subject is always on the support device, realizing the integration of the whole radiotherapy delivery process, reducing the waiting time of the subject from simulation positioning to radiotherapy delivery in the past, eliminating the possibility of changes and migrations of the region of interest during the waiting period of the subject, improving the consistency between simulation positioning and radiotherapy delivery, and helping to improve the accuracy of radiotherapy delivery.

[0110] In one embodiment, the step of obtaining the first four-dimensional FBCT image of the subject and the step of performing radiotherapy delivery on the subject according to the radiotherapy delivery plan are executed by the same radiotherapy delivery device.

[0111] In this embodiment, the step of obtaining the first four-dimensional FBCT image of the subject and the step of performing radiotherapy delivery on the subject according to the radiotherapy delivery plan are executed by the same radiotherapy delivery device, that is, the simulation positioning of the subject and the subsequent treatment use the same set of radiotherapy delivery devices.

[0112] The subject is moved to the position of the FBCT device through the support device, scanned to obtain the first four-dimensional FBCT image, and a planning image is obtained using the first four-dimensional FBCT image, so as to obtain a radiotherapy delivery plan based on the planning image. Then, the subject is moved to the corresponding position of the radiotherapy device through the support device, and the radiotherapy device is controlled to perform radiotherapy delivery on the subject based on the radiotherapy delivery plan. Optionally, the FBCT device and the radiotherapy device in the radiotherapy delivery device may be in the position relationship as shown above Figure 1 As shown, the FBCT device and the radiotherapy device in the radiotherapy delivery device may also be in a coplanar relationship. After scanning the subject under the FBCT device to obtain the first four-dimensional FBCT image, the support device does not have to be moved to a specific radiotherapy device, and the radiotherapy device can be directly controlled to perform radiotherapy delivery on the subject at this position based on the radiotherapy delivery plan.

[0113] In the embodiments of the present application, the scanning time of the first four-dimensional FBCT image is shorter, and the movement trajectory and movement range of the region of interest of the object can be obtained quickly. Moreover, the step of performing radiation delivery on the object according to the radiation delivery plan is executed by the same radiation delivery device, which reduces the waiting time between preoperative simulation positioning and intraoperative radiation therapy in the past, and reduces the possibility of the object's body position movement under the same set of radiation delivery devices, further improving the accuracy of radiation delivery.

[0114] It should be understood that although the steps in the flowcharts involved in the above embodiments are sequentially shown according to the indications of the arrows, these steps are not necessarily executed in the order indicated by the arrows. Unless there is a clear indication in this article, the execution of these steps has no strict order limit, and these steps can be executed in other orders. Moreover, at least a part of the steps in the flowcharts involved in the above embodiments may include multiple steps or multiple stages. These steps or stages are not necessarily executed at the same time, but can be executed at different times, and the execution order of these steps or stages is not necessarily sequential, but can be executed alternately or alternately with at least a part of other steps or steps or stages in other steps.

[0115] Based on the same inventive concept, the embodiments of the present application also provide a radiation delivery device for implementing the radiation delivery method involved above. The solution provided by this device to solve the problem is similar to the solution recorded in the above method. Therefore, the specific limitations in one or more embodiments of the radiation delivery device provided below can refer to the limitations on the radiation delivery method in the above text, and will not be repeated here.

[0116] In an exemplary embodiment, as Figure 7 shown, a radiation delivery device is provided, including: an acquisition unit 11, a calculation unit 12, and an execution unit 13, where:

[0117] The acquisition unit 11 is used to acquire the first four-dimensional FBCT image of the object;

[0118] The calculation unit 12 is used to generate a planned image according to the sub-images in the first four-dimensional FBCT image, and generate a radiation delivery plan for the object according to the planned image;

[0119] The execution unit 13 is used to perform radiation delivery on the object according to the radiation delivery plan.

[0120] In one embodiment, the calculation unit includes:

[0121] The first acquisition unit is used to acquire the motion information of the region of interest in the first four-dimensional FBCT image;

[0122] A first generation unit, configured to generate a planned image according to a sub-image in a first four-dimensional FBCT image if the motion information meets the preset motion information.

[0123] In one embodiment, the calculation unit further includes:

[0124] A second generation unit, configured to generate a radiation delivery plan for an object according to the planned image when the motion range of the region of interest in the first four-dimensional FBCT image is within the delineated range on the planned image; the motion information includes the motion range.

[0125] In one embodiment, the calculation unit of the radiation delivery device is further configured to generate a density projection image according to the sub-image; register the density projection image and the planned image to obtain a registered image; and determine whether the motion range is within the delineated range according to the registered image.

[0126] In one embodiment, the calculation unit further includes:

[0127] A second acquisition unit, configured to acquire a second four-dimensional FBCT image of the object;

[0128] A third generation unit, configured to perform radiation delivery on the object according to the radiation delivery plan when the motion range of the region of interest in the second four-dimensional FBCT image is within the delineated range on the planned image.

[0129] In one embodiment, the third generation unit is further configured to perform radiation delivery on the object according to the radiation delivery plan when the difference between the first respiration information and the second respiration information is within the difference range.

[0130] In one embodiment, the object remains on the support device during the execution of the steps of the method.

[0131] In one embodiment, the step of acquiring the first four-dimensional FBCT image of the object and the step of performing radiation delivery on the object according to the radiation delivery plan are executed by the same radiation delivery device.

[0132] Each module in the above radiation delivery device can be implemented in whole or in part by software, hardware, and their combination. The above modules can be embedded in the processor of the computer device in hardware form or be independent of it, or can be stored in the memory of the computer device in software form, so that the processor can call and execute the operations corresponding to the above modules.

[0133] In an exemplary embodiment, a computer device is provided. The computer device can be a server, and its internal structure diagram can be as Figure 8As shown. The computer device includes a processor, a memory, an input / output interface (Input / Output, abbreviated as I / O), and a communication interface. Among them, the processor, the memory, and the input / output interface are connected through a system bus, and the communication interface is connected to the system bus through the input / output interface. Among them, the processor of the computer device is used to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system, a computer program, and a database. The internal memory provides an environment for the operation of the operating system and the computer program in the non-volatile storage medium. The database of the computer device is used to store radiation delivery-related data. The input / output interface of the computer device is used to exchange information between the processor and external devices. The communication interface of the computer device is used to communicate with an external terminal through a network connection. When the computer program is executed by the processor, it implements a radiation delivery method.

[0134] Those skilled in the art can understand that Figure 8 the structure shown in is only a block diagram of some structures related to the solution of this application, and does not constitute a limitation on the computer device to which the solution of this application is applied. The specific computer device may include more or fewer components than those shown in the figure, or combine some components, or have a different component layout.

[0135] In an exemplary embodiment, a computer device is provided, including a memory and a processor. A computer program is stored in the memory. When the processor executes the computer program, the following steps are implemented:

[0136] Obtain the first four-dimensional FBCT image of the object;

[0137] Generate a planned image according to the sub-images in the first four-dimensional FBCT image;

[0138] Generate a radiation delivery plan for the object according to the planned image;

[0139] Perform radiation delivery on the object according to the radiation delivery plan.

[0140] In one embodiment, when the processor executes the computer program, the following steps are further implemented:

[0141] Obtain the motion information of the region of interest in the first four-dimensional FBCT image;

[0142] If the motion information meets the preset motion information, generate a planned image according to the sub-images in the first four-dimensional FBCT image.

[0143] In one embodiment, when the processor executes the computer program, the following steps are further implemented:

[0144] When the range of motion of the region of interest in the first four-dimensional FBCT image is within the delineated range on the planning image, a radiation delivery plan for the object is generated based on the planning image; the motion information includes the range of motion.

[0145] In one embodiment, when the processor executes the computer program, the following steps are further implemented:

[0146] Generate a density projection image based on the sub-images;

[0147] Register the density projection image and the planning image to obtain a registered image;

[0148] Determine whether the range of motion is within the delineated range based on the registered image.

[0149] In one embodiment, when the processor executes the computer program, the following steps are further implemented:

[0150] Obtain a second four-dimensional FBCT image of the object;

[0151] Perform radiation delivery to the object based on the second four-dimensional FBCT image and the radiation delivery plan.

[0152] In one embodiment, when the processor executes the computer program, the following steps are further implemented:

[0153] When the range of motion of the region of interest in the second four-dimensional FBCT image is within the delineated range on the planning image, perform radiation delivery to the object based on the radiation delivery plan.

[0154] In one embodiment, when the processor executes the computer program, the following steps are further implemented:

[0155] When the difference between the first respiratory information and the second respiratory information is within the difference range, perform radiation delivery to the object based on the radiation delivery plan.

[0156] In one embodiment, during the execution of the steps of the method, the object remains on the support device.

[0157] In one embodiment, the step of obtaining the first four-dimensional FBCT image of the object and the step of performing radiation delivery to the object based on the radiation delivery plan are performed by the same radiation delivery device.

[0158] In one embodiment, a computer-readable storage medium is provided, on which a computer program is stored. When the computer program is executed by a processor, the following steps are implemented:

[0159] Obtain a first four-dimensional FBCT image of the object;

[0160] Generate a planning image based on the sub-images in the first four-dimensional FBCT image;

[0161] Generate a radiation delivery plan for an object based on a planned image;

[0162] Perform radiation delivery to the object according to the radiation delivery plan.

[0163] In one embodiment, when the computer program is executed by a processor, the following steps are further implemented:

[0164] Obtain the motion information of the region of interest in the first four-dimensional FBCT image;

[0165] If the motion information meets the preset motion information, generate a planned image according to the sub-image in the first four-dimensional FBCT image.

[0166] In one embodiment, when the computer program is executed by a processor, the following steps are further implemented:

[0167] When the motion range of the region of interest in the first four-dimensional FBCT image is within the delineated range on the planned image, generate a radiation delivery plan for the object according to the planned image; the motion information includes the motion range.

[0168] In one embodiment, when the computer program is executed by a processor, the following steps are further implemented:

[0169] Generate a density projection image according to the sub-image;

[0170] Register the density projection image and the planned image to obtain a registered image;

[0171] Determine whether the motion range is within the delineated range according to the registered image.

[0172] In one embodiment, when the computer program is executed by a processor, the following steps are further implemented:

[0173] Obtain the second four-dimensional FBCT image of the object;

[0174] Perform radiation delivery to the object according to the second four-dimensional FBCT image and the radiation delivery plan.

[0175] In one embodiment, when the computer program is executed by a processor, the following steps are further implemented:

[0176] When the motion range of the region of interest in the second four-dimensional FBCT image is within the delineated range on the planned image, perform radiation delivery to the object according to the radiation delivery plan.

[0177] In one embodiment, when the computer program is executed by a processor, the following steps are further implemented:

[0178] When the difference between the first respiratory information and the second respiratory information is within the difference range, perform radiation delivery to the object according to the radiation delivery plan.

[0179] In one embodiment, during the execution of the steps of the method, the object remains on the support device.

[0180] In one embodiment, the step of acquiring a first four-dimensional FBCT image of the object and the step of performing radiation delivery to the object according to a radiation delivery plan are performed by the same radiation delivery device.

[0181] In one embodiment, a computer program product is provided, including a computer program which, when executed by a processor, implements the following steps:

[0182] Acquire a first four-dimensional FBCT image of the object;

[0183] Generate a planned image based on a sub-image in the first four-dimensional FBCT image;

[0184] Generate a radiation delivery plan for the object based on the planned image;

[0185] Perform radiation delivery to the object according to the radiation delivery plan.

[0186] In one embodiment, when the computer program is executed by a processor, the following steps are further implemented:

[0187] Acquire motion information of an area of interest in the first four-dimensional FBCT image;

[0188] If the motion information meets the preset motion information, generate a planned image based on a sub-image in the first four-dimensional FBCT image.

[0189] In one embodiment, when the computer program is executed by a processor, the following steps are further implemented:

[0190] When the motion range of the area of interest in the first four-dimensional FBCT image is within the delineated range on the planned image, generate a radiation delivery plan for the object based on the planned image; the motion information includes the motion range.

[0191] In one embodiment, when the computer program is executed by a processor, the following steps are further implemented:

[0192] Generate a density projection image based on the sub-image;

[0193] Register the density projection image and the planned image to obtain a registered image;

[0194] Determine whether the motion range is within the delineated range according to the registered image.

[0195] In one embodiment, when the computer program is executed by a processor, the following steps are further implemented:

[0196] Acquire a second four-dimensional FBCT image of the object;

[0197] Radiation delivery is performed on the subject according to the second four-dimensional FBCT image and the radiation delivery plan.

[0198] In one embodiment, when the computer program is executed by a processor, the following steps are further implemented:

[0199] When the movement range of the region of interest in the second four-dimensional FBCT image is within the delineated range on the planning image, radiation delivery is performed on the subject according to the radiation delivery plan.

[0200] In one embodiment, when the computer program is executed by a processor, the following steps are further implemented:

[0201] When the difference between the first respiratory information and the second respiratory information is within the difference range, radiation delivery is performed on the subject according to the radiation delivery plan.

[0202] In one embodiment, during the execution of the steps of the method, the subject remains on the support device.

[0203] In one embodiment, the step of acquiring the first four-dimensional FBCT image of the subject and the step of performing radiation delivery on the subject according to the radiation delivery plan are performed by the same radiation delivery device.

[0204] It should be noted that the user information (including but not limited to user device information, user personal information, etc.) and data (including but not limited to data for analysis, stored data, displayed data, etc.) involved in this application are all information and data authorized by the user or fully authorized by all parties, and the collection, use, and processing of relevant data need to comply with relevant regulations.

[0205] Those of ordinary skill in the art can understand that all or part of the processes in the methods of the above embodiments can be completed by instructing relevant hardware through a computer program. The computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above methods. Among them, any reference to a memory, database, or other medium used in the embodiments provided in the present application can include at least one of non-volatile and volatile memories. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory, optical memory, high-density embedded non-volatile memory, resistive random access memory (ReRAM), magnetoresistive random access memory (MRAM), ferroelectric random access memory (FRAM), phase change memory (PCM), graphene memory, etc. Volatile memory can include random access memory (RAM) or external cache memory, etc. By way of illustration and not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM), etc. The databases involved in the embodiments provided in the present application can include at least one of relational databases and non-relational databases. Non-relational databases can include distributed databases based on blockchain, etc., without limitation. The processors involved in the embodiments provided in the present application can be general-purpose processors, central processing units, graphics processing units, digital signal processors, programmable logic devices, data processing logics based on quantum computing, etc., without limitation.

[0206] The technical features of the above embodiments can be combined arbitrarily. For the sake of concise description, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered as the scope described in this specification.

[0207] The above-described embodiments merely represent several implementation manners of the present application. Their descriptions are relatively specific and detailed, but they should not be construed as limiting the scope of the patent of the present application. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present application, several modifications and improvements can still be made, and these all belong to the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the appended claims.

Claims

1. A radiation delivery method, characterized in that, The method includes: Obtaining a first four-dimensional FBCT image of an object; Generating a planning image based on sub-images in the first four-dimensional FBCT image; Generating a radiation delivery plan for the object according to the planning image; Performing radiation delivery on the object according to the radiation delivery plan.

2. The method according to claim 1, characterized in that, The generating a planning image based on sub-images in the first four-dimensional FBCT image includes: Obtaining motion information of a region of interest in the first four-dimensional FBCT image; If the motion information meets preset motion information, generating a planning image based on sub-images in the first four-dimensional FBCT image.

3. The method according to claim 2, wherein The motion information includes a motion range, and the generating a radiation delivery plan for the object according to the planning image includes: When the motion range of the region of interest in the first four-dimensional FBCT image is within the delineated range on the planning image, generating a radiation delivery plan for the object according to the planning image.

4. The method according to claim 3, characterized in that, The method further includes: Generating a density projection image based on the sub-images; Registering the density projection image and the planning image to obtain a registered image; Determining whether the motion range is within the delineated range according to the registered image.

5. The method according to claim 1, characterized in that, The performing radiation delivery on the object according to the radiation delivery plan includes: Obtaining a second four-dimensional FBCT image of the object; When the motion range of the region of interest in the second four-dimensional FBCT image is within the delineated range on the planning image, performing radiation delivery on the object according to the radiation delivery plan.

6. The method according to claim 5, characterized in that, The first four-dimensional FBCT image is obtained based on first motion information, the second four-dimensional FBCT image is obtained based on second motion information, and the performing radiation delivery on the object according to the radiation delivery plan includes: When the difference between the first motion information and the second motion information is within a difference range, performing radiation delivery on the object according to the radiation delivery plan.

7. The method according to claim 1, wherein During the execution of each step of the method, the object remains on a support device.

8. The method according to claim 1, wherein The step of obtaining a first four-dimensional FBCT image of the object and the step of performing radiation delivery on the object according to the radiation delivery plan are performed by the same radiation delivery device.

9. A radiation delivery device, characterized in that, The device includes: An obtaining unit for obtaining a first four-dimensional FBCT image of an object; A calculating unit for generating a planning image based on sub-images in the first four-dimensional FBCT image and generating a radiation delivery plan for the object according to the planning image; An executing unit for performing radiation delivery on the object according to the radiation delivery plan.

10. A computer-readable storage medium having a computer program stored thereon, characterized in that, When the computer program is executed by a processor, it implements the steps of the method according to any one of claims 1 to 8.

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