Traditional Chinese medicine composition for treating qi stagnation type constipation through paste massage

Abstract

The invention discloses a paste massage traditional Chinese medicine compound for treating qi stagnation type constipation. The traditional Chinese medicine composition is prepared from, by mass, 8-12 parts of radix codonopsis slices, 8-12 parts of radix linderae, 8-12 parts of betel nuts, 7-11 parts of agilawood, 8-12 parts of radix angelicae, 8-12 parts of radix clematidis, 8-12 parts of fructus cnidii, 8-12 parts of radix et rhizoma rhei, 12-18 parts of radix salviae miltiorrhizae, 8-12 parts of fructus amomi and 8-12 parts of sandalwood. The traditional Chinese medicine composition is an external plaster and can be used for treating qi stagnation type constipation.

Description

Technical Field

[0001] The present invention relates to a traditional Chinese medicine complex for treating qi stagnation type constipation by plaster massage. Background Art

[0002] Constipation is one of the most common gastrointestinal diseases in stroke patients with long-term bed rest. The main symptoms are difficult defecation, reduced frequency, or a feeling of uncleanness after each bowel movement. From the perspective of traditional Chinese medicine, constipation can be divided into heat accumulation, cold accumulation, qi deficiency, qi stagnation, etc., among which qi stagnation type is the most common. Long-term constipation can lead to diseases such as anal fissure and hemorrhoids. Traditional Chinese medicine syndrome differentiation and treatment have a good targeted therapeutic effect on it, including oral administration of traditional Chinese medicine, acupuncture, massage, etc., while a traditional Chinese medicine complex for treating qi stagnation type constipation by special plaster massage is rare. Summary of the Invention

[0003] The main purpose of the present invention is to provide a traditional Chinese medicine complex for treating qi stagnation type constipation by plaster massage.

[0004] The technical solution adopted by the present invention to solve its technical problems is as follows:

[0005] A traditional Chinese medicine complex for treating qi stagnation type constipation by plaster massage, by mass fraction, includes:

[0006] 8 - 12 parts of Codonopsis pilosula slices, 8 - 12 parts of Lindera aggregata, 8 - 12 parts of Areca catechu, 7 - 11 parts of Aquilaria sinensis, 8 - 12 parts of Angelica dahurica, 8 - 12 parts of Clematis chinensis, 8 - 12 parts of Cnidium monnieri, 8 - 12 parts of Rheum officinale, 12 - 18 parts of Salvia miltiorrhiza, 8 - 12 parts of Amomum villosum, 8 - 12 parts of Santalum album.

[0007] Further, by mass fraction, the traditional Chinese medicine complex includes 10 g of Codonopsis pilosula slices, 10 g of Lindera aggregata, 10 g of Areca catechu, 9 g of Aquilaria sinensis, 10 g of Angelica dahurica, 10 g of Clematis chinensis, 10 g of Cnidium monnieri, 10 g of Rheum officinale, 15 g of Salvia miltiorrhiza, 10 g of Amomum villosum, 10 g of Santalum album.

[0008] Further, each dose of the traditional Chinese medicine composition is equivalent to 91 g - 137 g of the raw material medicine.

[0009] Further, the traditional Chinese medicine complex is prepared by the following method: taking the raw material medicine according to the above mass fraction ratio and adjusting it into a paste with vinegar or vaseline.

[0010] The present invention also provides the use of the above-mentioned traditional Chinese medicine complex for treating qi stagnation type constipation by plaster massage in the preparation of a drug for treating constipation.

[0011] Further, the constipation is qi stagnation type constipation.

[0012] Further, the drug is an ointment.

[0013] Further, the drug is applied to the abdomen and the abdomen is massaged clockwise for 20 min each time, once a day.

[0014] Main clinical manifestations of qi-stagnation type constipation: Due to qi stagnation, the bowel fails to descend properly, the conduction of the gastrointestinal tract is blocked, and the internal feces cannot be transported smoothly, manifested as constipation and discomfort during defecation. Clinically, patients have symptoms such as discomfort during defecation, abdominal distension, borborygmus, fullness and oppression in the chest and hypochondrium, frequent hiccups or flatulence, dark red tongue, thin coating, and taut pulse. In the formula of the present invention, lindera aggregata and areca catechu are used as the monarch drugs to regulate qi and relieve fullness, and promote qi movement and relieve stagnation; agalloch eaglewood, sandalwood, amomum villosum, and rheum palmatum are used as the minister drugs. Agalloch eaglewood, sandalwood, and amomum villosum regulate the qi of the spleen and stomach, enabling the orderly rise and fall of the qi of the spleen and stomach. Rheum palmatum purges and promotes defecation. Angelica dahurica, clematis chinensis, fructus cnidii, and salvia miltiorrhiza are used as the assistant drugs to dispel wind, promote blood circulation, and warm and dredge, enabling the qi movement of the intestine to be smooth; codonopsis pilosula is used as the guiding drug to replenish qi and strengthen the spleen, and promote the qi movement of the intestine. The whole formula together exerts the effects of regulating qi and promoting bowel movement, and promoting qi movement and relieving stagnation, and is applicable to qi-stagnation type constipation. Detailed implementation manners

[0015] Example 1

[0016] Codonopsis pilosula tablets 10g, Lindera aggregata 10g, Areca catechu 10g, Agalloch eaglewood 9g, Angelica dahurica 10g, Clematis chinensis 10g

[0017] Fructus cnidii 10g, Rheum palmatum 10g, Salvia miltiorrhiza 15g, Amomum villosum 10g, Sandalwood 10g

[0018] The above is one dose.

[0019] Example 2

[0020] Codonopsis pilosula tablets 8g, Lindera aggregata 12g, Areca catechu 8g, Agalloch eaglewood 11g, Angelica dahurica 8g, Clematis chinensis 12g

[0021] Fructus cnidii 8g, Rheum palmatum 12g, Salvia miltiorrhiza 12g, Amomum villosum 12g, Sandalwood 8g

[0022] The above is one dose.

[0023] Example 3

[0024] Codonopsis pilosula tablets 12g, Lindera aggregata 8g, Areca catechu 12g, Agalloch eaglewood 7g, Angelica dahurica 12g, Clematis chinensis 8g

[0025] Fructus cnidii 12g, Rheum palmatum 8g, Salvia miltiorrhiza 18g, Amomum villosum 8g, Sandalwood 12g

[0026] The above is one dose.

[0027] From June 2023 to June 2024, the applicant collected a total of 87 stroke patients with qi stagnation type constipation. The patients were aged 45 - 65 years old. Among them, there were 44 male patients and 43 female patients. The main symptoms were: 1) Unsmooth defecation; 2) Abdominal distension. Secondary symptoms were: 1) Borborygmus; 2) Fullness and oppression in the chest and hypochondrium; 3) Frequent hiccups or passing of flatus. Tongue and pulse manifestations were: Dark red tongue, thin coating, and taut pulse. Syndrome differentiation showed that due to qi stagnation, the fu-organs lost their normal descending function, the conduction of the intestines and stomach was blocked, and the internal waste could not be transported smoothly, so the stool was constipated and defecation was unsmooth; when the qi of the fu-organs was blocked and the normal ascending and descending function was disrupted, the stomach qi rebelled upward, resulting in hiccups, fullness and oppression in the chest and hypochondrium; qi stagnation and disharmony of the spleen's transportation function led to abdominal distension and borborygmus; dark red tongue, thin coating, and taut pulse were signs of qi stagnation in the intestines. The diagnosis was qi stagnation type constipation. The research was carried out by using the method of random grouping and positive control. According to the random number method in the order of medical treatment, the patients were divided into 2 groups. There were 47 cases in the observation group and 40 cases in the control group. There were no statistically significant differences in terms of gender, age, disease course, etc. between the two groups (P > 0.05), and they were comparable.

[0028] Methods

[0029] Both groups were given routine nursing according to medical advice: (1) Instruct the patients to keep the habit of drinking plenty of boiled water, 1500 - 2000 mL per day, and ensure an intake of 20 - 35 g of dietary fiber per day; (2) Let the patients defecate regularly. Even if they have no urge to defecate, they need to develop the habit of squatting or sitting to form a regular defecation pattern for the intestines and stomach; (3) Conduct appropriate anal lifting exercises, etc.; (4) Provide a safe environment and guide the patients to adopt the best defecation posture; (5) Encourage the patients to actively adjust their mental state and keep their body and mind relaxed.

[0030] Control group: Apply an appropriate amount of paraffin oil to the abdomen and massage the abdomen clockwise for 20 minutes each time, once a day. The treatment course was 7 days, for a total of 1 course.

[0031] Observation group: The main components of the traditional Chinese medicine complex (Example 1): 10 g of Lindera aggregata, 10 g of Areca catechu, 9 g of Aquilaria sinensis, 10 g of Angelica dahurica, 10 g of Clematis chinensis, 10 g of Cnidium monnieri, 10 g of Rheum palmatum, 15 g of Salvia miltiorrhiza, 10 g of Amomum villosum, 10 g of Santalum album, 10 g of Codonopsis pilosula tablets. Grind the above-mentioned drugs into fine powder and mix them into a paste with an appropriate amount of vaseline. Apply it to the abdomen and massage the abdomen clockwise for 20 minutes each time, once a day. The treatment course was 7 days, for a total of 1 course.

[0032] The efficacy evaluation criteria were based on the "Expert Consensus on the Diagnosis and Treatment of Constipation in Traditional Chinese Medicine (2017)":

[0033] Cured: The patient's stool characteristics are normal, and the patient defecates every day, with other symptoms disappearing;

[0034] Markedly effective: The patient's stool characteristics are close to normal, and the defecation interval is within 2 days, with most of the other symptoms disappearing;

[0035] Effective: The condition of the patient's dry and hard stools has improved, and the defecation interval is within 4 days, and other symptoms have also improved;

[0036] Ineffective: The stool characteristics of the patient have not changed, other symptoms have not improved, and the defecation interval exceeds 4 days.

[0037] Total treatment effective rate = (number of cured patients + number of markedly effective patients + number of effective patients) / total number of patients × 100%.

[0038] Safety observation: Vital signs, blood routine, urine routine, electrocardiogram, liver and kidney function tests were performed before and after treatment, and the occurrence time, severity, duration, measures taken and outcome of adverse events were recorded.

[0039] The comparison of the control group and the observation group for curative effect is as shown in Table 1 below. It was found that when comparing the curative effects of the two groups, the total effective rate of the observation group was significantly higher than that of the control group, and the difference was statistically significant (P < 0.05).

[0040] Table 1

[0041] Cured Markedly effective Effective Ineffective Total effective rate (cases) Control group: 40 cases 2 10 18 10 75％ Observation group: 47 cases 6 16 20 5 89.36％

[0042] Z value 2.056 P value 0.04

[0043] As mentioned above, it is only a preferred embodiment of the present invention, so the scope of implementation of the present invention cannot be limited thereby. That is, equivalent changes and modifications made according to the scope of the present invention patent and the content of the specification should still fall within the scope covered by the present invention.

Claims

1. A traditional Chinese medicine complex for treating qi stagnation type constipation by medicated friction, by mass parts, comprising: 8 - 12 parts of Codonopsis pilosula slices, 8 - 12 parts of Lindera aggregata, 8 - 12 parts of Areca catechu, 7 - 11 parts of Aquilaria sinensis, 8 - 12 parts of Angelica dahurica, 8 - 12 parts of Clematis chinensis, 8 - 12 parts of Cnidium monnieri, 8 - 12 parts of Rheum palmatum, 12 - 18 parts of Salvia miltiorrhiza, 8 - 12 parts of Amomum villosum, 8 - 12 parts of Santalum album.

2. The traditional Chinese medicine complex for treating qi stagnation type constipation by medicated friction according to claim 1, wherein: By mass parts, comprising 10 g of Codonopsis pilosula slices, 10 g of Lindera aggregata, 10 g of Areca catechu, 9 g of Aquilaria sinensis, 10 g of Angelica dahurica, 10 g of Clematis chinensis, 10 g of Cnidium monnieri, 10 g of Rheum palmatum, 15 g of Salvia miltiorrhiza, 10 g of Amomum villosum, 10 g of Santalum album.

3. The traditional Chinese medicine complex for treating qi-stagnation type constipation by plaster massage according to claim 1, wherein: Each dose of the traditional Chinese medicine composition is equivalent to 91 g - 137 g of the raw materials.

4. The traditional Chinese medicine complex for treating qi-stagnation type constipation by paste massage according to claim 1, wherein: The traditional Chinese medicine complex is prepared by the following method: taking the raw materials according to the said mass parts ratio and adjusting them into a paste with vinegar or petrolatum.

5. Use of the traditional Chinese medicine complex according to any one of claims 1 to 4 in the preparation of a medicament for treating constipation.

6. The use according to claim 5, characterized in that: The constipation is qi stagnation type constipation.

7. The use according to claim 6, characterized in that: The qi stagnation type is qi stagnation type constipation of stroke patients.

8. The use according to claim 6, characterized in that: The medicament is an ointment.

9. The use according to claim 8, characterized in that: When using the ointment, it is applied to the abdomen and the abdomen is massaged clockwise for 20 min each time, once a day.