Intelligent homogenizing device for medical examination

Abstract

The invention discloses an intelligent homogenizing device for medical examination, which comprises a main body case, a central processing unit and a power supply module are arranged in an inner cavity of the main body case, a stirring module driving unit capable of translating is arranged at the top of the inner cavity of the main body case, and a homogenizing bin module and a cleaning module are arranged at the bottom of the stirring module driving unit; the stirring module controls lifting and translation through a driving unit, integrates sealing and stirring components, and is used for performing homogenization treatment on a sample and monitoring pressure and temperature parameters in a homogenization process in real time; the homogenate bin module is provided with a refrigerating function and a replaceable sample container fixing unit, and is used for maintaining a low-temperature environment and adapting to homogenate containers of different specifications; and the cleaning module is provided with a cleaning and disinfecting assembly and is used for cleaning and sterilizing after homogenizing. The stirring shaft is driven by the translation platform to perform spiral track motion, and the stirring range covers the whole space of the cup body in cooperation with multi-form adaptation of the detachable homogenizing blade, so that the problems of bottom precipitation and edge residue of traditional single-shaft stirring are avoided.

Description

Technical Field

[0001] The present invention relates to the technical field of medical testing, and particularly to an intelligent homogenization device for medical testing. Background Art

[0002] Sample pretreatment in medical testing is the core link affecting the accuracy of test results. Especially for the homogenization of biological samples such as tissues and blood, it is necessary to achieve component homogenization while ensuring the integrity of cell structure. Traditional homogenization techniques mainly rely on the principle of mechanical fragmentation, and decompose samples by means of blade rotation, grinding, or ultrasonic vibration. In recent years, with the popularization of automated equipment, homogenization devices have gradually developed towards integration and intelligence, but the key technical bottlenecks still need to be broken through.

[0003] Traditional homogenization devices mostly adopt single-axis stirring or simple shear fragmentation, relying on fixed rotation speeds and single blades. For high-viscosity samples, "homogenization dead corners" such as bottom precipitation and edge residues are likely to occur, resulting in uneven particle distribution; when dealing with fragile cells, high-speed shearing often causes cell membrane rupture and serious loss of biological activity. Although some devices introduce ultrasonic assistance, most ultrasonic modules are external, lack coordination with the stirring system, have low energy transfer efficiency, and are difficult to dynamically adjust the fragmentation strategy according to sample characteristics.

[0004] The parameter adjustment of existing devices mostly relies on manual presetting and lacks a real-time feedback mechanism. For example, pressure sensors are only used to monitor overload protection and are not linked with the stirring strategy; most temperature control modules are open-loop controls and cannot dynamically adjust the refrigeration power according to sample viscosity and processing progress. For more than 200 kinds of biological samples, traditional devices need to manually switch programs, and the homogenization parameters of novel virus samples often require repeated trial and error, which is time-consuming and laborious and poses an operational risk.

[0005] Traditional homogenization cups mostly use threaded connections or snap fixes. When replacing, it is necessary to manually align and tighten, which takes 5 - 10 minutes, and the sealing reliability depends on manual inspection, and liquid leakage is likely to occur during high-speed stirring; the cleaning process relies on manual disassembly and brushing with a brush, with a high protein residue rate and a significant risk of cross-contamination.

[0006] To solve the above problems, the present invention provides an intelligent homogenization device for medical testing. Summary of the Invention

[0007] The technical problem to be solved by the present invention is to overcome the defects of the prior art and provide an intelligent homogenization device for medical testing.

[0008] To solve the above technical problems, the present invention provides the following technical solutions:

[0009] The present invention provides an intelligent homogenizing device for medical examination, comprising a main body chassis, wherein the inner cavity of the main body chassis is provided with a central processing unit and a power supply module, and characterized in that a translationally movable stirring module driving unit is provided at the top of the inner cavity of the main body chassis, and a homogenizing chamber module and a cleaning module are provided at the bottom of the stirring module driving unit;

[0010] The stirring module is controlled by a driving unit to lift and translate, and is integrated with sealing and stirring components to perform sample homogenization and monitor pressure and temperature parameters during the homogenization process in real time;

[0011] The homogenization chamber module is equipped with a refrigeration function and a replaceable sample container fixing unit, which is used to maintain a low temperature environment and adapt to homogenization containers of different specifications;

[0012] The cleaning module is equipped with a cleaning and disinfection component for completing cleaning and sterilization after homogenization.

[0013] As a preferred technical solution of the present invention, the stirring module includes an anti-overflow cover, a servo motor is installed on the top of the anti-overflow cover, the servo motor is connected to a stirring shaft through a coupling, the stirring shaft passes through the anti-overflow cover, and a detachable homogenizing blade is installed at the bottom, and a pressure transmitter, a temperature sensor and a piezoelectric vibration accelerometer are embedded around the middle of the bottom end of the anti-overflow cover;

[0014] The stirring module driving unit is a translation stage, which has a built-in XYZ three-axis linear motor module to drive the homogenizing blade to perform spiral trajectory motion. The trajectory parameters include pitch and rotation radius, and the translation stage is equipped with a CCD camera to identify the position.

[0015] As a preferred technical solution of the present invention, the homogenization chamber module includes a semiconductor refrigerator, the temperature conduction surface of the semiconductor refrigerator is attached with a heat-conducting metal sheet, the top of the heat-conducting metal sheet is adsorbed with a sample cup body, and the periphery of the heat-conducting metal sheet is provided with a cup body restraint mechanism;

[0016] The cup body restraint mechanism includes a circular ring limiting hollow disk, an arc-shaped clamping arm and an electric push rod. The arc-shaped clamping arm is distributed around the interlayer of the circular ring limiting hollow disk and moves synchronously. The electric push rod is transmission-connected with the arc-shaped clamping arm to push the arc-shaped clamping arm to rotate and open and close. A pressure sensor is arranged on the inner side of the arc-shaped clamping arm.

[0017] As a preferred technical solution of the present invention, the cleaning module includes a cleaning cylinder. At the bottom end of the cleaning cylinder, there is a cleaning liquid storage tank and a waste liquid collection bucket. At the inner bottom end of the cleaning cylinder, there is a rotating cleaning spray head. On the inner wall of the cleaning cylinder, there are multiple waterproof ultraviolet disinfection lamps. At the inner bottom end of the cleaning cylinder, there is a diversion groove, and the groove wall is inclined to guide the cleaning liquid to flow towards the edge of the cup body. The drain hole at the bottom end of the diversion groove is connected to the waste liquid collection bucket through a hose. The liquid inlet end of the rotating cleaning spray head is connected to the cleaning liquid storage tank through a hose, and one-way solenoid valves are installed on all the hoses.

[0018] As a preferred technical solution of the present invention, a two-stage filtration module is provided in the waste liquid collection bucket, with pore sizes of 10μm and 0.22μm respectively. The inclination angle of the groove wall of the diversion groove is 30° - 45°, and the diameter of the drain hole at the bottom end of the diversion groove is 5mm - 8mm.

[0019] As a preferred technical solution of the present invention, the central processing unit internally has a vibration spectrum analysis model. It collects the vibration signals at the stirring shaft through a piezoelectric vibration accelerometer and performs a 4096-point FFT analysis on the signals. When high-frequency resonance or load mutation is detected, the following operations are performed:

[0020] Trigger the emergency reverse rotation of the stirring shaft, and the reverse torque ≥ 80% of the rated value;

[0021] Start the forced cooling of the semiconductor refrigerator, and the temperature difference ≥ 10℃ / s;

[0022] Lift the stirring blade away from the sample interface through the translation stage;

[0023] The central processing unit also integrates a dynamic power distribution model to allocate loads according to priorities:

[0024] The refrigeration system accounts for 40%, and adopts the PID temperature control algorithm;

[0025] The stirring motor accounts for 35%, and adopts torque feedback regulation;

[0026] The cleaning module accounts for 25%, and starts and stops as needed;

[0027] When the sample temperature exceeds the threshold, the power of the refrigeration system is increased to 60%, and the stirring motor synchronously reduces its speed by 20%.

[0028] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0029] 1: The present invention drives the stirring shaft to execute a spiral trajectory motion through a translation stage, and cooperates with the multi-form adaptation of the detachable homogenizing blade, so that the stirring range covers the entire space of the cup body, avoiding the problems of bottom precipitation and edge residue in traditional single-axis stirring. This structure dynamically adjusts the stirring trajectory and blade type to evenly disperse the crushing resistance, significantly enhancing the homogenization uniformity of samples with different viscosities and densities, and solving the contradiction between insufficient fragmentation of high-viscosity tissues and excessive shearing of fragile cells.

[0030] 2: The present invention integrates pressure, temperature and vibration sensors on the anti-overflow cover to collect sample status data in real time. The central processor combines the preset sample processing protocol to automatically adjust the stirring speed, refrigeration power and motion trajectory, significantly reducing the operation complexity and sample processing risk.

[0031] 3: The sample cup body of the present invention can be quickly replaced without tools and is accurately positioned; the cleaning module integrates the functions of high-pressure flushing and ultraviolet disinfection of a rotating spray head to automatically complete residue removal and sterilization treatment, reducing the time-consuming of manual disassembly and cleaning and the risk of cross-contamination. Description of the Drawings

[0032] The drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation to the present invention. In the drawings:

[0033] Figure 1 is the front view of the overall structure of the present invention;

[0034] Figure 2 is the internal view of the overall structure of the present invention;

[0035] Figure 3 is the exploded view of the structure of the homogenization chamber module of the present invention;

[0036] Figure 4 is the enlarged view of the structure of the stirring module of the present invention;

[0037] Figure 5 is the schematic diagram of the structure of the cup body restraint mechanism of the present invention;

[0038] Figure 6 is the flow chart of the vibration spectrum analysis algorithm of the present invention;

[0039] In the figure: 1. Main body chassis; 2. Translation stage; 41. Anti-overflow cover; 42. Servo motor; 43. Stirring shaft; 44. Pressure transmitter; 45. Temperature sensor; 46. Piezoelectric vibration accelerometer; 51. Semiconductor refrigerator; 52. Heat-conducting metal sheet; 53. Sample cup body; 54. Cup body binding mechanism; 61. Cleaning cylinder; 62. Cleaning liquid storage tank; 63. Waste liquid collection bucket; 64. Rotary cleaning spray head; 65. Ultraviolet disinfection lamp; 66. Flow guide groove; 541. Ring-shaped limiting hollow disc; 542. Arc-shaped clamping arm; 543. Electric push rod; 5421. Pressure sensor. Detailed implementation manners

[0040] The preferred embodiments of the present invention will be described below with reference to the accompanying drawings. It should be understood that the preferred embodiments described herein are only for the purpose of illustrating and explaining the present invention, and are not used to limit the present invention.

[0041] Embodiment 1

[0042] As Figure 1-6 shown, the present invention provides an intelligent homogenization device for medical testing, including a main body chassis 1. A central processor and a power module are arranged in the inner cavity of the main body chassis 1. A translatable stirring module driving unit is arranged at the top of the inner cavity of the main body chassis 1. A homogenization chamber module and a cleaning module are arranged at the bottom of the stirring module driving unit;

[0043] The stirring module is controlled to lift and translate by the driving unit, and integrates a sealing and stirring assembly, which is used to perform homogenization treatment on the sample and real-time monitor the pressure and temperature parameters during the homogenization process;

[0044] The homogenization chamber module is configured with a refrigeration function and a replaceable sample container fixing unit, which is used to maintain a low-temperature environment and adapt to different specifications of homogenization containers;

[0045] The cleaning module is configured with a cleaning and disinfection assembly, which is used to complete the cleaning and sterilization after homogenization.

[0046] Furthermore, the stirring module includes an anti-overflow cover 41. The anti-overflow cover 41 is made of polyether ether ketone. A servo motor 42 is installed at the top end of the anti-overflow cover 41. The servo motor 42 is connected with a stirring shaft 43 through a coupling. The stirring shaft 43 penetrates through the anti-overflow cover 41, and a detachable homogenization blade is installed at the bottom end. A pressure transmitter 44, a temperature sensor 45 and a piezoelectric vibration accelerometer 46 are embedded around the middle of the bottom end of the anti-overflow cover 41; the range of the pressure transmitter 44 is 0-100 kPa, the response time is 1 ms, the temperature sensor 45 is PT1000, the temperature measurement range is -20-150 °C, and the frequency range of the piezoelectric vibration accelerometer 46 is 0.1 Hz-20 kHz, and the sensitivity is 10 mV / g;

[0047] The driving unit of the stirring module is a translation stage 2, which has a built-in XYZ three-axis linear motor module to drive the homogenizing blade to perform spiral trajectory motion. The trajectory parameters include pitch: 2-15mm and rotation radius: 3-20mm, and the translation stage 2 is equipped with a CCD camera to identify the position.

[0048] Furthermore, the homogenization chamber module includes a semiconductor refrigerator 51, a heat-conducting metal sheet 52 is attached to the temperature conduction surface of the semiconductor refrigerator 51, a sample cup 53 is adsorbed on the top of the heat-conducting metal sheet 52, and a cup restraining mechanism 54 is arranged on the periphery of the heat-conducting metal sheet 52;

[0049] The cup body restraining mechanism 54 includes a circular ring limiting hollow disk 541, an arc-shaped clamping arm 542 and an electric push rod 543. The arc-shaped clamping arm 542 is distributed around the interlayer of the circular ring limiting hollow disk 541 and moves synchronously. The electric push rod 543 is connected to the arc-shaped clamping arm 542 for driving, pushing the arc-shaped clamping arm 542 to rotate and open and close. A pressure sensor 5421 is arranged on the inner side of the arc-shaped clamping arm 542. When the sample cup body 53 is placed on the heat-conducting metal sheet 52, the arc-shaped clamping arm 542 is pushed by the electric push rod 543 to rotate and close and clamp the outside of the sample cup body 53. At the same time, the pressure sensor 5421 detects the contact pressure between the clamping arm and the cup body and feeds back to the central processing unit to ensure that the fixing accuracy error of the sample cup body 53 is ≤0.1mm.

[0050] Furthermore, the cleaning module includes a cleaning cylinder 61, the bottom end of which is provided with a cleaning liquid storage tank 62 and a waste liquid collection bucket 63, a rotating cleaning nozzle 64 is provided at the inner bottom end of the cleaning cylinder 61, and a plurality of waterproof ultraviolet disinfection lamps 65 are provided on the inner wall of the cleaning cylinder 61, a guide groove 66 is provided at the inner bottom end of the cleaning cylinder 61, and the groove wall is inclined to guide the cleaning liquid to flow to the edge of the cup body, the bottom drainage hole of the guide groove 66 is connected to the waste liquid collection bucket 63 through a hose, the liquid inlet end of the rotating cleaning nozzle 64 is connected to the cleaning liquid storage tank 62 through a hose, and a one-way solenoid valve is installed on the hose.

[0051] Furthermore, a two-stage filtration module is provided in the waste liquid collection barrel 63, with pore sizes of 10 μm and 0.22 μm respectively, the groove wall inclination angle of the guide groove 66 is 30°-45°, and the bottom drainage hole diameter of the guide groove 66 is 5mm-8mm.

[0052] Furthermore, the central processor has a built-in vibration spectrum analysis model, which collects the vibration signal at the stirring shaft 43 through the piezoelectric vibration accelerometer 46, and performs a 4096-point FFT analysis on the signal. When a high-frequency resonance is detected: >10kHz or a load mutation: the pressure change rate is >5kPa / s, the following operations are performed:

[0053] Trigger the stirring shaft 43 to reverse urgently, and the reverse torque ≥ 80% of the rated value;

[0054] Start the semiconductor cooler 51 to force cooling, with a temperature difference ≥ 10 °C / s;

[0055] Lift the stirring blade away from the sample interface through the translation stage 2;

[0056] The central processing unit also integrates a dynamic power distribution model to allocate loads by priority:

[0057] The refrigeration system accounts for 40%, and uses the PID temperature control algorithm;

[0058] The stirring motor accounts for 35%, and uses torque feedback regulation;

[0059] The cleaning module accounts for 25% and starts and stops as needed;

[0060] When the sample temperature exceeds the threshold, the power of the refrigeration system is increased to 60%, and the stirring motor synchronously reduces the speed by 20%.

[0061] Specifically, the main chassis 1 of the present invention integrates a central processing unit, a power module, an edge computing unit, and a data storage module. The central processing unit connects to each functional module through the CAN bus, processes sensor data in real time, and executes a closed-loop control algorithm. A 7-inch touch screen is installed on the top of the chassis, supporting parameter setting, real-time monitoring, and data export.

[0062] The translation stage 2 is built with an XYZ three-axis linear motor module to drive the stirring component to execute a spiral trajectory motion. The servo motor 42 drives the stirring shaft 43 through a coupling, and the end is connected to a detachable homogenizing blade through a snap-in interface. The detachable homogenizing blade includes a cross-shaped titanium alloy cutter head, a ball-milling ceramic cutter head, and a micro-needle cutter head, etc.

[0063] The cross-shaped titanium alloy cutter head is suitable for high-toughness fibrous tissues and tissues with relatively hard textures. For example: high-toughness fibrous tissues such as muscle and connective tissues; tissues with relatively hard textures such as liver and kidney.

[0064] The ball-milling ceramic cutter head is suitable for some fragile cell tissues, such as nerve cells, stem cells, etc.

[0065] The micro-needle cutter head is suitable for tissues with loose textures or very small sample amounts to be processed. Such as adipose tissue, spongy tissue and other tissues with loose textures; a small amount of biopsy tissue, precious cell samples, etc.

[0066] The semiconductor cooler 51 is attached to the heat-conducting metal sheet 52, and the temperature of the sample cup 53 is maintained at 2 - 8 °C through the PID algorithm. The cup binding mechanism 54 consists of a circular ring limiting hollow disc 541 and three groups of arc-shaped clamping arms 542. The electric push rod 543 drives the clamping arms to close synchronously, and the pressure sensor 5421 monitors the clamping force in real time. The target value is 5 - 10 N to ensure that the positioning error of the cup is ≤ 0.1 mm. The sample cup 53 supports the replacement of multiple specifications.

[0067] When processing samples, here "liver tissue" is taken as an example. The user selects the preset program of "liver tissue homogenate" through the touch screen, and the central processing unit automatically sets it by calling the tissue characteristic database, which contains 200 kinds of sample parameters.

[0068] After the translation stage 2 drives the stirring module to move above the homogenization chamber module and then press down to the top of the sample cup 53, the anti-overflow cover 41 seals with the sample cup 53, and the pressure transmitter 44 detects the initial contact force and then starts the servo motor.

[0069] The central processing unit controls the translation stage 2 to perform spiral stirring with a pitch of 10 mm and a radius of 15 mm according to the preset protocol: for liver tissue, the target particle size ≤ 50 μm. The initial speed of the servo motor 42 is 2000 rpm, and the pressure transmitter 44 feeds back the viscosity change in real time. When the detected viscosity exceeds the threshold of 10 kPa·s, the speed is automatically increased to 2400 rpm, and the semiconductor cooler maintains the cup temperature at 4 °C. If the piezoelectric vibration accelerometer 46 monitors abnormal vibration of the blade, such as fiber entanglement, the stirring shaft 43 performs an emergency reverse rotation and lifts 4 mm away from the sample interface to avoid damage to the tool head.

[0070] When facing high-viscosity samples, the system synchronously increases the stirring intensity and adjusts the low-temperature environment to enhance the crushing efficiency while protecting the sample activity; for new samples, the matching parameters can be called through the preset database without manual trial and error.

[0071] After homogenization, the translation stage 2 lifts the stirring module, the cup binding mechanism 54 loosens, and the cup is taken out for subsequent detection. After wiping the stirring module, it moves above the cleaning module, and the translation stage 2 drives the stirring module to press down into the cleaning cylinder 61. The cleaning cylinder 61 matches the anti-overflow cover 41, and the CCD camera assists in positioning to ensure accurate insertion. Then, the cleaning liquid in the cleaning liquid storage tank 62 is extracted and sprayed from the rotating cleaning nozzle 64. The cleaning liquid is sprayed in a direct water flow and a fan-shaped water flow. After 60 seconds of cleaning, the waste liquid is collected through the diversion groove 66 and flows into the waste liquid collection bucket 63.

[0072] Finally, it should be noted that the above are only the preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. An intelligent homogenization device for medical testing, comprising a main chassis (1). A central processor and a power module are arranged in the inner cavity of the main chassis (1), and it is characterized in that, The top of the inner cavity of the main machine case (1) is provided with a translationally movable stirring module driving unit, and the bottom of the stirring module driving unit is provided with a homogenizing chamber module and a cleaning module; The stirring module is controlled by a driving unit to lift and translate, and is integrated with sealing and stirring components to perform sample homogenization and monitor pressure and temperature parameters during the homogenization process in real time; The homogenization chamber module is equipped with a refrigeration function and a replaceable sample container fixing unit, which is used to maintain a low temperature environment and adapt to homogenization containers of different specifications; The cleaning module is equipped with a cleaning and disinfection component for completing cleaning and sterilization after homogenization.

2. The intelligent homogenization device for medical testing according to claim 1, wherein The stirring module comprises an anti-overflow cover (41), a servo motor (42) is installed at the top of the anti-overflow cover (41), the servo motor (42) is connected to a stirring shaft (43) via a coupling, the stirring shaft (43) passes through the anti-overflow cover (41), and a detachable homogenizing blade is installed at the bottom, and a pressure transmitter (44), a temperature sensor (45) and a piezoelectric vibration accelerometer (46) are embedded around the middle of the bottom end of the anti-overflow cover (41); The stirring module driving unit is a translation stage (2), wherein the translation stage (2) has a built-in XYZ three-axis linear motor module to drive the homogenizing blade to perform spiral trajectory motion, wherein the trajectory parameters include the pitch and the rotation radius, and the translation stage (2) is equipped with a CCD camera to identify the position.

3. An intelligent homogenization device for medical testing according to claim 2, characterized in that, The homogenization chamber module comprises a semiconductor refrigerator (51), a temperature conduction surface of the semiconductor refrigerator (51) is bonded with a heat-conducting metal sheet (52), a sample cup (53) is adsorbed on the top of the heat-conducting metal sheet (52), and a cup restraining mechanism (54) is arranged on the periphery of the heat-conducting metal sheet (52); The cup body restraining mechanism (54) comprises a circular ring limiting hollow disk (541), an arc-shaped clamping arm (542) and an electric push rod (543); the arc-shaped clamping arm (542) is distributed in the interlayer of the circular ring limiting hollow disk (541) and moves synchronously; the electric push rod (543) is connected to the arc-shaped clamping arm (542) by transmission, and pushes the arc-shaped clamping arm (542) to realize rotation and opening and closing; a pressure sensor (5421) is arranged on the inner side of the arc-shaped clamping arm (542).

4. An intelligent homogenizing device for medical tests according to claim 1, characterized in that, The cleaning module comprises a cleaning cylinder (61), the bottom end of which is provided with a cleaning liquid storage tank (62) and a waste liquid collection bucket (63), the inner bottom end of which is provided with a rotating cleaning nozzle (64), the inner wall of which is provided with a plurality of waterproof ultraviolet disinfection lamps (65), a guide groove (66) is provided at the inner bottom end of the cleaning cylinder (61), and the groove wall is in an inclined state to guide the cleaning liquid to flow toward the edge of the cup body, the bottom drainage hole of the guide groove (66) is connected to the waste liquid collection bucket (63) through a hose, the liquid inlet end of the rotating cleaning nozzle (64) is connected to the cleaning liquid storage tank (62) through a hose, and a one-way solenoid valve is installed on each hose.

5. An intelligent homogenization device for medical testing according to claim 4, characterized in that, The waste liquid collection bucket (63) is provided with two - stage filtering modules with pore sizes of 10 μm and 0.22 μm respectively. The inclination angle of the groove wall of the diversion groove (66) is 30° - 45°, and the diameter of the drainage hole at the bottom end of the diversion groove (66) is 5 mm - 8 mm.

6. The intelligent homogenizing device for medical testing according to claim 1, wherein, The central processor has a built - in vibration spectrum analysis model. It collects the vibration signals at the stirring shaft (43) through a piezoelectric vibration accelerometer (46), and performs 4096 - point FFT analysis on the signals. When high - frequency resonance or load mutation is detected, the following operations are performed: Trigger the emergency reverse rotation of the stirring shaft (43), and the reverse torque ≥ 80% of the rated value; Start the semiconductor cooler (51) for forced cooling, with a temperature difference ≥ 10 °C / s; Lift the stirring blade away from the sample interface through the translation stage (2); The central processor also integrates a dynamic power distribution model to allocate loads according to priorities: The refrigeration system accounts for 40%, and adopts the PID temperature control algorithm; The stirring motor accounts for 35%, and adopts torque feedback regulation; The cleaning module accounts for 25%, and starts and stops as needed; When the sample temperature exceeds the threshold, the power of the refrigeration system is increased to 60%, and the stirring motor speed is synchronously reduced by 20%.

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