Preparation equipment for tanshinone molecularly imprinted polymer

Abstract

The invention relates to preparation equipment for a tanshinone molecularly imprinted polymer, and belongs to the technical field of tanshinone molecularly imprinted polymer, the preparation equipment comprises a connecting bin, the bottom surface of the connecting bin is fixedly connected with four supporting columns, the top surface of the connecting bin is fixedly connected with a placing bin, the top surface of the connecting bin is fixedly connected with a feeding bin, and the feeding bin is fixedly connected with a discharging bin. The connecting bin is provided with a feeding assembly used for conveying raw materials, the feeding assembly comprises a discharging pipe, one end of the discharging pipe is fixedly connected to the inner top wall of the connecting bin, and the other end of the discharging pipe penetrates through the connecting bin and extends into the feeding bin. According to the preparation equipment for the tanshinone molecularly imprinted polymer, under the action of the feeding bin and the placement bin, solid raw materials and an initiator are stored and do not need to be taken from the outside, the preparation efficiency is improved, under the action of the placement groove, ice blocks are placed, the temperature in the placement bin is reduced, and the safety is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of tanshinone molecularly imprinted polymers, and particularly to a preparation device for tanshinone molecularly imprinted polymers. Background Technique

[0002] Salvia miltiorrhiza has the effects of removing stasis and relieving pain, promoting blood circulation and dredging meridians, and clearing the heart and relieving restlessness. It is a traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases. The chemical components of Salvia miltiorrhiza are mainly divided into two categories: fat-soluble components and water-soluble components. The fat-soluble components are mainly diterpenoid compounds, such as tanshinone IIA, cryptotanshinone, and tanshinone I, etc. The metabolites in vivo exhibit various pharmacological effects.

[0003] The preparation method and application of a molecularly imprinted polymer are disclosed in the publication number CN102167777B. This patent discloses a technical solution for convenient preparation, which solves the problems of complex preparation process, high cost, and unfavorable large-scale preparation and application in the existing separation and preparation of Salvia miltiorrhiza.

[0004] When the device is in use, the preparation process is simplified through one-step mixing, saving the preparation time. However, when the initiator is stored, it needs to be placed inside the refrigerator, and when adding it, it needs to be taken out, reducing the preparation efficiency. Therefore, a preparation method and application of a molecularly imprinted polymer are proposed to solve the above problems. Summary of the Invention

[0005] Aiming at the deficiencies of the prior art, the present invention provides a preparation device for tanshinone molecularly imprinted polymers, which has the advantage of convenient storage and solves the problem that the existing preparation device for tanshinone molecularly imprinted polymers is not convenient for storing raw materials.

[0006] To achieve the above object, the present invention provides the following technical solutions:

[0007] A preparation device for tanshinone molecularly imprinted polymers includes a connection bin. The bottom surface of the connection bin is fixedly connected with four support columns. The top surface of the connection bin is fixedly connected with a placement bin. The top surface of the connection bin is fixedly connected with a feed bin. A feed assembly for conveying raw materials is provided on the connection bin.

[0008] The feeding assembly includes a discharge pipe, one end of which is fixedly connected to the inner top wall of the connection bin, and the other end of which passes through the connection bin and extends into the interior of the feeding bin. A placement groove is formed in the top surface of the placement bin. A cover plate is placed on the top surface of the feeding bin. A first temperature detector is fixedly installed on the top surface of the cover plate, and one end of the first temperature detector extends through the cover plate and into the interior of the placement bin. Connecting plates are fixedly connected to both the left side surface and the right side surface of the placement bin. Positioning holes are fixedly connected to the top surfaces of the two connecting plates. Two positioning rods are fixedly connected to the bottom surface of the cover plate, and one ends of the two positioning rods respectively extend into the two positioning holes. Rubber rings are fixedly sleeved on the outer peripheral walls of the two positioning rods. A liquid discharge pipe is fixedly connected to the inner bottom wall of the placement bin, and one end of the liquid discharge pipe passes through the placement bin and extends into the interior of the connection bin. First solenoid valves are fixedly installed on the outer peripheral walls of both the liquid discharge pipe and the discharge pipe. A spray head is fixedly installed on the bottom surface of the liquid discharge pipe.

[0009] A mixing assembly for mixing raw materials is provided on the connection bin, and a monitoring assembly is provided on the connection bin.

[0010] Further, the placement bin is in the shape of a cuboid with a hollow interior and a missing top surface, and the liquid discharge pipe is fixedly connected to the connection bin.

[0011] Further, the cover plate fits with the placement bin, and the feeding bin is located on the left side of the placement bin.

[0012] Further, the positioning rod and the positioning hole are in clearance fit, and the rubber ring fits with the positioning hole.

[0013] Further, the mixing assembly includes a driving motor, the driving motor is fixedly installed on the bottom surface of the connection bin, an output shaft of the driving motor is fixedly connected to a driving rod, one end of the driving rod passes through the connection bin and extends to its inner top wall, first stirring rods are fixedly connected to both the left side surface and the right side surface of the driving rod, a plurality of second stirring rods are fixedly connected to both the left inner wall and the right inner wall of the connection bin, a discharge pipe is fixedly connected to the inner bottom wall of the connection bin, and one end of the discharge pipe passes through the connection bin and extends to its bottom. A second solenoid valve is fixedly installed on the outer peripheral wall of the discharge pipe.

[0014] Further, the driving rod is rotatably connected to the connection bin through a bearing, and the connection bin is in the shape of a hollow cylinder.

[0015] Further, the plurality of first stirring rods and the plurality of second stirring rods are all located inside the connection bin, and the plurality of first stirring rods and the plurality of second stirring rods are cross - distributed.

[0016] Further, the monitoring assembly includes two second temperature detectors. One ends of the two second temperature detectors are respectively fixedly installed on the top surface and the bottom surface of the connection bin, and the other ends of both extend through the connection bin and extend to the interior thereof.

[0017] Furthermore, an installation groove is formed in the bottom surface of the connection bin, and a heating coil is fixedly installed inside the installation groove, and the installation groove is an annular groove.

[0018] Compared with the prior art, the present invention provides a preparation device for tanshinone molecularly imprinted polymer, which has the following beneficial effects:

[0019] 1. For the preparation device of tanshinone molecularly imprinted polymer, under the action of the feeding bin and the placement bin, the solid raw materials and initiators are respectively stored, and there is no need to take them from the outside, which improves the preparation efficiency. Under the action of the placement groove, ice cubes are placed to cool the temperature inside the placement bin, improving safety;

[0020] 2. For the preparation device of tanshinone molecularly imprinted polymer, under the action of the first stirring rod and the second stirring rod, the raw materials and initiators are mixed, which is convenient for the staff to operate. Under the action of the heating coil, the inside of the connection bin can be heated conveniently. At the same time, under the action of the first temperature detector and the second temperature detector, the temperatures inside the placement bin and the connection bin are respectively monitored, improving the use effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 is a three-dimensional structure diagram of the present invention;

[0022] Figure 2 is a schematic diagram of the internal structure of the present invention;

[0023] Figure 3 is an enlarged schematic diagram of the internal structure of the placement bin in the present invention;

[0024] Figure 4 is the present invention Figure 3 is an enlarged schematic diagram of the structure of A in the present invention.

[0025] In the figure: 1 connection bin, 2 placement bin, 3 cover plate, 4 feeding bin, 5 support column, 6 installation groove, 7 heating coil, 8 second stirring rod, 9 first stirring rod, 10 driving rod, 11 liquid outlet pipe, 12 first solenoid valve, 13 first temperature detector, 14 discharge pipe, 15 second temperature detector, 16 driving motor, 17 discharge pipe, 18 second solenoid valve, 19 placement groove, 20 nozzle, 21 connecting plate, 22 rubber ring, 23 positioning rod, 24 positioning hole. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0026] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present invention.

[0027] Please refer to Figures 1 to 4 , a preparation device for tanshinone molecularly imprinted polymer in this embodiment, includes a connection bin 1. The bottom surface of the connection bin 1 is fixedly connected with four support columns 5. The top surface of the connection bin 1 is fixedly connected with a placement bin 2. The top surface of the connection bin 1 is fixedly connected with a feed bin 4. A feed assembly for transporting raw materials is provided on the connection bin 1.

[0028] The feed assembly includes a discharge pipe 14. One end of the discharge pipe 14 is fixedly connected to the inner top wall of the connection bin 1, and the other end thereof penetrates through the connection bin 1 and extends into the interior of the feed bin 4. A placement groove 19 is opened on the top surface of the placement bin 2. A cover plate 3 is placed on the top surface of the feed bin 4. A first temperature detector 13 is fixedly installed on the top surface of the cover plate 3 and extends through the cover plate 3 and into the interior of the placement bin 2 at one end. The left side and the right side of the placement bin 2 are both fixedly connected with connecting plates 21. The top surfaces of the two connecting plates 21 are both fixedly connected with positioning holes 24. The bottom surface of the cover plate 3 is fixedly connected with two positioning rods 23, and one end of each of the two positioning rods 23 extends into the two positioning holes 24 respectively. Rubber rings 22 are fixedly sleeved on the outer peripheral walls of the two positioning rods 23. The inner bottom wall of the placement bin 2 is fixedly connected with a liquid outlet pipe 11 that penetrates through the placement bin 2 and extends into the interior of the connection bin 1. First solenoid valves 12 are fixedly installed on the outer peripheral walls of the liquid outlet pipe 11 and the discharge pipe 14. A nozzle 20 is fixedly installed on the bottom surface of the liquid outlet pipe 11.

[0029] Among them, the shape of the placement bin 2 is a cuboid with a hollow interior and a missing top surface. The liquid outlet pipe 11 is fixedly connected to the connection bin 1. The cover plate 3 fits with the placement bin 2. The feed bin 4 is located on the left side of the placement bin 2. The positioning rod 23 and the positioning hole 24 are in clearance fit. The rubber ring 22 fits with the positioning hole 24.

[0030] Specifically, the raw materials are poured into the interior of the connection bin 1, the ice cubes are placed into the interior of the placement groove 19, the initiator is poured into the interior of the placement bin 2, the push plate cover 3 is pushed, the cover 3 fits with the placement bin 2, the positioning rod 23 is inserted into the interior of the positioning hole 24 to restrict the cover 3, and through the fit between the rubber ring 22 and the positioning hole 24, the cover 3 is fixed. Under the action of the first temperature detector 13, the temperature inside the placement bin 2 is monitored. The first solenoid valve 12 is activated, and the raw materials enter the interior of the connection bin 1 through the conveyance of the discharge pipe 14. The initiator enters the interior of the liquid outlet pipe 11, and under the action of the nozzle 20, the initiator is drip-irrigated into the interior of the connection bin 1.

[0031] It should be noted that the nozzle 20 is a conventional device well-known to the public in the prior art, and its specific structure and working principle will not be elaborated in this text.

[0032] Please refer to Figures 1 to 4 , in this embodiment, a mixing assembly for mixing the raw materials is provided on the connection bin 1. The mixing assembly includes a driving motor 16, the driving motor 16 is fixedly installed on the bottom surface of the connection bin 1, the output shaft of the driving motor 16 is fixedly connected to a driving rod 10 that penetrates through one end of the connection bin 1 and extends to its inner top wall. The left side and the right side of the driving rod 10 are both fixedly connected with first stirring rods 9, the left inner wall and the right inner wall of the connection bin 1 are both fixedly connected with a plurality of second stirring rods 8, and the inner bottom wall of the connection bin 1 is fixedly connected with a discharge pipe 17 that penetrates through one end of the connection bin 1 and extends to its bottom. A second solenoid valve 18 is fixedly installed on the outer peripheral wall of the discharge pipe 17.

[0033] Among them, the driving rod 10 is rotationally connected to the connection bin 1 through a bearing. The shape of the connection bin 1 is a hollow cylinder. A plurality of first stirring rods 9 and a plurality of second stirring rods 8 are all located inside the connection bin 1, and a plurality of first stirring rods 9 and a plurality of second stirring rods 8 are cross-distributed.

[0034] Specifically, the driving motor 16 is activated, the output shaft of the driving motor 16 drives the driving rod 10 to rotate, so that the first stirring rod 9 rotates. Under the action of the first stirring rod 9 and the second stirring rod 8, the raw materials and the initiator are mixed. After the mixing is completed, the second solenoid valve 18 is activated, and through the action of the discharge pipe 17, the mixed raw materials are discharged from the connection bin 1.

[0035] It should be noted that both the first solenoid valve 12 and the second solenoid valve 18 are conventional devices well-known to the public in the prior art, and their specific structures and working principles will not be elaborated in this text.

[0036] Please refer to Figures 1 to 4, in this embodiment, a monitoring component is provided on the connection bin 1. The monitoring component includes two second temperature detectors 15. One ends of the two second temperature detectors 15 are respectively fixedly installed on the top surface and the bottom surface of the connection bin 1, and the other ends thereof all penetrate through the connection bin 1 and extend to the inside thereof. An installation groove 6 is formed on the bottom surface of the connection bin 1, and a heating coil 7 is fixedly installed inside the installation groove 6.

[0037] Among them, the installation groove 6 is an annular groove.

[0038] Specifically, start the heating coil 7, and the heating coil 7 heats the inside of the connection bin 1. Under the action of the second temperature detector 15, the temperature of the connection bin 1 is monitored.

[0039] It should be noted that the heating coil 7, the first temperature detector 13 and the second temperature detector 15 are all conventional devices well known to the public in the prior art, and their specific structures and working principles will not be elaborated in this text.

[0040] The working principle of the above embodiment is as follows:

[0041] Pour the raw materials into the inside of the connection bin 1, place the ice cubes into the inside of the placement groove 19, pour the initiator into the inside of the placement bin 2, push the push plate cover 3, the cover 3 fits with the placement bin 2, and the positioning rod 23 is inserted into the positioning hole 24 to fix the cover 3. Under the action of the first temperature detector 13, the temperature inside the placement bin 2 is monitored. Start the first solenoid valve 12, and the raw materials enter the inside of the connection bin 1 through the transportation of the discharge pipe 14. Under the action of the nozzle 20, the initiator is drip-irrigated into the inside of the connection bin 1. Start the heating coil 7, and the heating coil 7 heats the inside of the connection bin 1. Under the action of the second temperature detector 15, the temperature of the connection bin 1 is monitored. Start the drive motor 16, and the output shaft of the drive motor 16 drives the drive rod 10 to rotate, so that the first stirring rod 9 rotates. Under the action of the first stirring rod 9 and the second stirring rod 8, the raw materials and the initiator are mixed. After mixing, through the action of the discharge pipe 17, the mixed raw materials are discharged from the connection bin 1.

[0042] The installation methods, connection methods or setting methods disclosed in the embodiment are all common mechanical connection methods, and any method that can achieve its beneficial effects can be implemented. In addition, the electrical components in this embodiment are all electrically connected to the main controller and the power supply. The main controller can be a conventional known device such as a computer that plays a control role. Those skilled in the art can realize the control of the electrical components through simple programming, and the existing publicly disclosed power connection technology also belongs to the common knowledge in this field. Therefore, the specific structural composition and working principle thereof will not be elaborated too much in this embodiment.

[0043] It should be noted that, in this document, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprising", "including" or any other variant thereof are intended to cover non-exclusive inclusion, such that a process, method, article or device comprising a series of elements not only includes those elements but also includes other elements not expressly listed, or elements inherent to such process, method, article or device. Without further limitation, an element defined by the statement "comprising an..." does not exclude the presence of additional identical elements in the process, method, article or device comprising said element.

[0044] Although embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the invention, and the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A preparation device for tanshinone molecularly imprinted polymer, comprising a connection bin (1), characterized in that: The bottom surface of the connection bin (1) is fixedly connected with four support columns (5), the top surface of the connection bin (1) is fixedly connected with a placement bin (2), the top surface of the connection bin (1) is fixedly connected with a feed bin (4), and a feed assembly for conveying raw materials is arranged on the connection bin (1). The feed assembly includes a discharge pipe (14). One end of the discharge pipe (14) is fixedly connected to the inner top wall of the connection bin (1), and the other end thereof penetrates through the connection bin (1) and extends into the interior of the feed bin (4). A placement groove (19) is formed in the top surface of the placement bin (2). A cover plate (3) is placed on the top surface of the feed bin (4). A first temperature detector (13) is fixedly installed on the top surface of the cover plate (3) and extends through the cover plate (3) and into the interior of the placement bin (2). Connecting plates (21) are fixedly connected to both the left side surface and the right side surface of the placement bin (2). Positioning holes (24) are fixedly connected to the top surfaces of the two connecting plates (21). Positioning rods (23) with a quantity of two and one ends respectively extending into the two positioning holes (24) are fixedly connected to the bottom surface of the cover plate (3). Rubber rings (22) are fixedly sleeved on the outer peripheral walls of the two positioning rods (23). A liquid discharge pipe (11) with one end penetrating through the placement bin (2) and extending into the interior of the connection bin (1) is fixedly connected to the inner bottom wall of the placement bin (2). First electromagnetic valves (12) are fixedly installed on the outer peripheral walls of both the liquid discharge pipe (11) and the discharge pipe (14). A spray head (20) is fixedly installed on the bottom surface of the liquid discharge pipe (11). A mixing assembly for mixing raw materials is arranged on the connection bin (1), and a monitoring assembly is arranged on the connection bin (1).

2. The preparation device for tanshinone molecularly imprinted polymer according to claim 1, wherein: The placement bin (2) is in the shape of a cuboid with a hollow interior and a missing top surface, and the liquid discharge pipe (11) is fixedly connected to the connection bin (1).

3. The preparation device for tanshinone molecularly imprinted polymer according to claim 1, wherein: The cover plate (3) fits with the placement bin (2), and the feed bin (4) is located on the left side of the placement bin (2).

4. The preparation device for tanshinone molecularly imprinted polymer according to claim 1, characterized in that: The positioning rod (23) and the positioning hole (24) are in clearance fit, and the rubber ring (22) fits with the positioning hole (24).

5. The preparation device for tanshinone molecularly imprinted polymer according to claim 1, characterized in that: The mixing assembly includes a driving motor (16). The driving motor (16) is fixedly installed on the bottom surface of the connection bin (1). The output shaft of the driving motor (16) is fixedly connected to a driving rod (10) with one end penetrating through the connection bin (1) and extending to its inner top wall. First stirring rods (9) are fixedly connected to both the left side surface and the right side surface of the driving rod (10). A plurality of second stirring rods (8) are fixedly connected to both the left inner wall and the right inner wall of the connection bin (1). A discharge pipe (17) with one end penetrating through the connection bin (1) and extending to its bottom is fixedly connected to the inner bottom wall of the connection bin (1). A second electromagnetic valve (18) is fixedly installed on the outer peripheral wall of the discharge pipe (17).

6. The preparation device for tanshinone molecularly imprinted polymer according to claim 5, wherein: The driving rod (10) is rotationally connected to the connection bin (1) through a bearing, and the connection bin (1) is in the shape of a hollow cylinder.

7. The preparation device for tanshinone molecularly imprinted polymer according to claim 5, characterized in that: A plurality of the first stirring rods (9) and a plurality of the second stirring rods (8) are both located inside the connection bin (1), and the plurality of the first stirring rods (9) and the plurality of the second stirring rods (8) are cross - distributed.

8. The preparation device for tanshinone molecularly imprinted polymer according to claim 5, characterized in that: The monitoring assembly includes two second temperature detectors (15). One ends of the two second temperature detectors (15) are respectively fixedly installed on the top surface and the bottom surface of the connection bin (1), and the other ends of them both penetrate through the connection bin (1) and extend to the inside thereof.

9. The preparation device for tanshinone molecularly imprinted polymer according to claim 8, characterized in that: An installation groove (6) is formed on the bottom surface of the connection bin (1), and a heating coil (7) is fixedly installed inside the installation groove (6), and the installation groove (6) is an annular groove.

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