Multi-site regulation reagent oscillation vortex instrument

Abstract

The invention relates to a multi-site regulation reagent oscillation vortex instrument, and discloses an oscillation vortex instrument which enables a sliding block to slide in a sliding groove by manually rotating a regulation handle and utilizing thread transmission, further drives a reagent tube containing device to slide so as to realize the position regulation of a reagent tube, and drives the reagent tube to rotate through a rotating motor so as to meet the mixing requirement of different reagents. The invention relates to a reagent tube containing device which is characterized by comprising a supporting square block, a rotating motor, a transmission shaft, a rotating square body, a sliding groove, a sliding block, a threaded rod, an adjusting handle, a rotating disc, a reagent tube containing device body and a reagent tube groove, the rotating motor is arranged in the supporting square block and fixedly connected with the supporting square block, and one end of the transmission shaft is fixedly connected with a motor shaft of the rotating motor; the transmission shaft vertically and upwards extends from one end to penetrate through the top end of the supporting square block to the other end, the middle of the bottom face of the rotating square body is fixedly connected with the other end of the transmission shaft, the rotating square body is composed of a U-shaped long strip and a square plate, a plurality of sliding grooves are formed in the inner side face of the U-shaped long strip of the rotating square body, and the sliding blocks are in sliding connection with the rotating square body through the sliding grooves.

Description

Technical Field

[0001] A multi-site adjustable reagent shaker-vortexer of the present invention relates to a shaker-vortexer that meets the mixing requirements of various reagents, belonging to the technical field of vibration instruments. In particular, it relates to a shaker-vortexer that adjusts the position of the reagent tube by manually rotating an adjustment handle to drive a slider to slide in a chute through screw transmission, thereby driving the sliding of the reagent tube holding device, and rotates the reagent tube by a rotating motor to meet different actual mixing requirements. Background Art

[0002] In the field of modern scientific experiments, there are extremely high requirements for reagent mixing operations. The performance of the vortexer directly affects the accuracy and reliability of experimental results. When a traditional vortexer is used, it mainly drives the reagent tube to rotate on its own axis, and relies on centrifugal force to form a vortex in the liquid to achieve mixing. However, the distribution of this vortex flow in the reagent tube may not be uniform, and there will be differences in the flow velocity and mixing degree of the liquid near the tube wall and the tube center. Especially for high-viscosity liquids or suspensions containing relatively large particles, it is difficult to achieve a highly uniform mixing state of the liquid throughout the reagent tube only by self-rotation. Moreover, during the self-rotation process, friction and shear forces will be generated between the liquid and the tube wall, as well as between different layers within the liquid. For some liquids that are sensitive to temperature or shear force, long-term self-rotation may cause local overheating, resulting in the denaturation of components in the liquid or chemical reactions, or the destruction of the structures of biomolecules, polymers, etc. in the liquid due to excessive shear force, affecting the accuracy of experimental results.

[0003] Publication No. CN207330957U discloses a vortex oscillation mixing device, including a vortexer, a shock pad, a support shaft, a buffer pad, and a fixed tray. At the upper center of the vortexer, a support shaft is coaxially made, and the fixed tray is horizontally fixedly installed at the upper end of the support shaft. The two sides of the buffer pad have adhesiveness and can be detachably adhered to the culture bottle fixed tray or the well plate fixed tray. The vortex oscillation mixing device is provided with different trays for cell culture bottles and culture plates, and several fixed slides are provided on the trays of the culture plates, which are matched with various specifications of cell culture bottles. However, the above-mentioned oscillation mixing device mainly realizes mixing by generating a vortex by the vortexer, and its liquid flow pattern is relatively single, and only relies on the vortex force to mix the liquid. For some complex samples or high-viscosity liquids, it may not be able to achieve sufficient mixing uniformity. Summary of the Invention

[0004] In order to improve the above situation, a multi-site adjustable reagent shaker-vortexer of the present invention provides a shaker-vortexer that adjusts the position of the reagent tube by manually rotating an adjustment handle to drive a slider to slide in a chute through screw transmission, thereby driving the sliding of the reagent tube holding device, and rotates the reagent tube by a rotating motor to meet the mixing of different reagents.

[0005] The multi-site adjustable reagent shaker and vortex mixer of the present invention is realized as follows: The multi-site adjustable reagent shaker and vortex mixer of the present invention is composed of a support square block, a rotating motor, a transmission shaft, a rotating cube, a chute, a slider, a threaded rod, an adjusting handle, a turntable, a reagent tube holding device, and a reagent tube slot. The support square block is of a hollow structure. The rotating motor is placed inside the support square block and fixedly connected to the support square block. One end of the transmission shaft is fixedly connected to the motor shaft of the rotating motor. The transmission shaft extends vertically upward from one end through the top of the support square block to the other end, and a support bearing is arranged between the transmission shaft and the support square block. The middle of the bottom surface of the rotating cube is fixedly connected to the other end of the transmission shaft. The rotating cube is composed of a U-shaped long strip and a square plate. The square plate is fixedly placed on the inner side surface of the U-shaped long strip near one end. A plurality of chutes are opened on the inner side surface of the U-shaped long strip of the rotating cube. The slider is slidably connected to the rotating cube through the chute. A threaded hole is opened through the slider. One end of the threaded rod is rotatably connected to the square plate of the rotating cube, and a support bearing is arranged between the threaded rod and the rotating cube. The threaded rod is threadedly connected to the slider through the threaded hole in the slider. One end of the threaded rod is fixedly connected to the adjusting handle. The turntable is fixedly connected to the top surface of the slider. The reagent tube holding device is fixedly placed on the turntable and is arranged near the middle. A reagent tube slot is opened at the top of the reagent tube holding device. Furthermore, a rubber ring is fixedly placed on the side surface of the reagent tube slot. The inside of the rubber ring is of a hollow structure. A plurality of the rubber rings are arranged at equal intervals along the axial direction of the reagent tube slot. Furthermore, a shock-absorbing pad is fixedly placed at the bottom end of the support square block. Beneficial effects

[0006] 1. Flexibly control the sliding amplitude of the test tube and quickly adapt to the experimental requirements.

[0007] 2. Promote more irregular flow of the liquid in the tube, enhance the convection effect, and improve the mixing uniformity and efficiency.

[0008] 3. Stable structure and simple operation. Description of the drawings

[0009] Figure 1 It is a three-dimensional structure diagram of the multi-site adjustable reagent shaker and vortex mixer of the present invention; Figure 2 It is a three-dimensional structure diagram of the multi-site adjustable reagent shaker and vortex mixer of the present invention; Figure 3Stereoscopic structure diagram of Embodiment 2 of a multi-site adjustment reagent shaker-vortexer of the present invention; Figure 4 Stereoscopic structure diagram of Embodiment 3 of a multi-site adjustment reagent shaker-vortexer of the present invention. Accompanying drawings

[0010] Among them are: reagent tube slot (1), reagent tube holding device (2), turntable (3), adjustment handle (4), support block (5), rotating cube (6), sliding groove (7), threaded rod (8), slider (9), transmission shaft (10), rotating motor (11), rubber ring (12), shock pad (13). Detailed implementation manners Embodiment 1

[0011] A multi-site adjustment reagent shaker-vortexer of the present invention is composed of a support block (5), a rotating motor (11), a transmission shaft (10), a rotating cube (6), a sliding groove (7), a slider (9), a threaded rod (8), an adjustment handle (4), a turntable (3), a reagent tube holding device (2), and a reagent tube slot (1). The support block (5) is of a hollow structure. The rotating motor (11) is placed inside the support block (5) and is fixedly connected to the support block (5). One end of the transmission shaft (10) is fixedly connected to the motor shaft of the rotating motor (11). The transmission shaft (10) extends vertically upward from one end through the top of the support block (5) to the other end, and a support bearing is provided between the transmission shaft (10) and the support block (5). The middle of the bottom surface of the rotating cube (6) is fixedly connected to the other end of the transmission shaft (10). The rotating cube (6) is composed of a U-shaped long strip and a square plate. The square plate is fixedly placed on the inner side surface of the U-shaped long strip near one end. A plurality of sliding grooves (7) are opened on the inner side surface of the U-shaped long strip of the rotating cube (6). Preferably, the inner surface of the sliding groove (7) is polished. The slider (9) is slidably connected to the rotating cube (6) through the sliding groove (7). A through threaded hole is opened inside the slider (9). Preferably, the slider (9) is made of lightweight aluminum alloy. One end of the threaded rod (8) is rotatably connected to the square plate of the rotating cube (6), and a support bearing is provided between the threaded rod (8) and the rotating cube (6). The threaded rod (8) is threadedly connected to the slider (9) through the threaded hole in the slider (9). Preferably, the threaded rod (8) is made of high-strength stainless steel and its surface is nitrided to enhance wear resistance. One end of the threaded rod (8) is fixedly connected to the adjustment handle (4). Preferably, the adjusting handle (4) has a triangular prism structure designed according to ergonomics and is provided with a rubber anti-slip sleeve on its surface. The turntable (3) is fixedly connected to the top surface of the slider (9). Preferably, the turntable is made of a high molecular composite material, and a metal skeleton is embedded inside to enhance strength and durability. The reagent tube holding device (2) is fixedly placed on the turntable (3) and is arranged close to the middle. Preferably, the reagent tube holding device (2) is integrally formed of elastic silica gel material. A reagent tube slot (1) is opened at the top of the reagent tube holding device (2). During use, place the reagent tube in the reagent tube slot (1), manually rotate the adjusting handle (4), which drives the threaded rod (8) to rotate. Through the threaded connection between the threaded rod (8) and the slider (9), the slider (9) slides within the rotating cube (6), thereby adjusting the distance between the reagent tube holding device (2) and the motor shaft of the rotating motor (11). Drive the rotating motor (11) to drive the reagent tube holding device (2) and the reagent tube inside to rotate. When the reagent tube holding device (2) coincides with the motor shaft of the rotating motor (11), it drives the reagent tube to rotate itself to form a vortex for mixing. When the reagent tube holding device (2) deviates from the motor shaft of the rotating motor (11), control the rotating motor (11) to rotate forward and backward reciprocally, which can make the reagent tube slide circularly reciprocally around the motor shaft of the rotating motor (11), so that the liquid in the reagent tube is subjected to inertial forces with continuously changing directions and magnitudes at different positions, prompting the liquid to generate more irregular flows in the tube, enhancing the convection effect, and improving the mixing uniformity and efficiency. By adjusting the distance between the reagent tube holding device (2) and the motor shaft of the rotating motor (11), control the mixing intensity and amplitude to achieve precise control of the mixing process. Example 2

[0012] The difference between this embodiment and Embodiment 1 is that: a rubber ring (12) is fixedly arranged on the side of the reagent tube slot (1). The inside of the rubber ring (12) is a hollow structure, and a plurality of the rubber rings (12) are arranged at equal intervals along the axial direction of the reagent tube slot (1). During use, the friction force with the reagent tube can be increased through the rubber ring (12), effectively preventing the reagent tube from easily deviating from its fixed position under the action of centrifugal force, ensuring the smooth progress of the experiment and the safety of the experimental environment. At the same time, it can adapt to small changes in the size of the reagent tube, making the device have stronger versatility. Example 3

[0013] The difference between this embodiment and Embodiment 1 is that a shock pad (13) is fixedly disposed at the bottom end of the support block (5). During use, it can alleviate the vibration of the device, effectively reduce the vibration transmitted to the rotating motor (11), reduce the risk of damage to the rotating motor (11), extend the service life of the rotating motor (11), thereby reducing the maintenance and replacement costs of the instrument, and improving the reliability and stability of the instrument; The inner surface of the chute (7) is designed with a polished surface, which reduces the friction when the slider (9) moves in the chute (7) and extends the service life of the device; The slider (9) is designed to be made of lightweight aluminum alloy. The lightweight design reduces the energy consumption of the overall device and improves the movement flexibility at the same time, ensuring a smoother rotation and movement process; The threaded rod (8) is made of high-strength stainless steel and is designed with a nitriding treatment on the surface to enhance wear resistance, which improves the anti-fatigue ability and corrosion resistance of the threaded rod and is suitable for long-term use; The adjusting handle (4) is designed with an ergonomic triangular prism structure and is provided with a rubber anti-slip sleeve on the surface. The ergonomic triangular prism structure fits the human hand-holding habit, making the operation more comfortable and labor-saving. The rubber anti-slip sleeve further enhances the friction and prevents slipping during adjustment; The reagent tube holding device (2) is designed to be integrally formed of elastic silica gel material, which can adapt to reagent tubes of different sizes, provide good buffer protection, and prevent the reagent tubes from breaking due to collision; It is possible to manually rotate the adjusting handle (4) to make the slider (9) slide in the chute (7) by screw drive, and then drive the reagent tube holding device (2) to slide to realize the position adjustment of the reagent tube, and drive the reagent tube to rotate by the rotating motor (11) to meet the purpose of mixing different reagents.

[0014] It should be noted that unless otherwise clearly specified and limited, the terms "placed", "connected", and "joined" should be understood in a broad sense. For example, they can be fixed connection methods such as hemmed connection, rivet connection, pin connection, bonding connection, and welding connection, or detachable connection methods such as threaded connection, snap connection, and hinge connection, or integral connection, or electrical connection, or directly connected, or indirectly connected through an intermediate medium, and can be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific situations.

[0015] It should be further pointed out that when describing the above specific embodiments, for the sake of simplicity and clarity, only the differences from other embodiments are described. However, those skilled in the art should know that the above specific embodiments are also independent technical solutions in themselves.

Claims

1. A multi-site adjustment reagent oscillator vortex mixer, characterized in that: It is composed of a support block, a rotating motor, a transmission shaft, a rotating cube, a sliding groove, a slider, a threaded rod, an adjusting handle, a turntable, a reagent tube holding device and a reagent tube groove. The rotating motor is placed inside the support block and fixedly connected to the support block. One end of the transmission shaft is fixedly connected to the motor shaft of the rotating motor. The transmission shaft extends vertically upward from one end through the top of the support block to the other end. The middle of the bottom surface of the rotating cube is fixedly connected to the other end of the transmission shaft. The rotating cube is composed of a U-shaped strip and a square plate. A plurality of sliding grooves are formed on the inner side surface of the U-shaped strip of the rotating cube. The slider is slidably connected to the rotating cube through the sliding groove. A threaded hole is formed through the inside of the slider. The threaded rod is rotatably connected to the square plate of the rotating cube near one end. The threaded rod is threadedly connected to the slider through the threaded hole in the slider. One end of the threaded rod is fixedly connected to the adjusting handle. The turntable is fixedly connected to the top surface of the slider. The reagent tube holding device is fixedly placed on the turntable and is arranged near the middle. A reagent tube groove is formed at the top of the reagent tube holding device.

2. A multi-site adjustment reagent oscillator according to claim 1, characterized in that A rubber ring is fixedly placed on the side surface of the reagent tube groove. The inside of the rubber ring is a hollow structure. A plurality of the rubber rings are arranged at equal intervals along the axial direction of the reagent tube groove.

3. A multi-site adjustment reagent shaker vortexer according to claim 1, characterized in that A shock-absorbing pad is fixedly placed at the bottom end of the support block.

4. A multi-site adjustment reagent shaker vortexer according to claim 1, characterized in that The support block is a hollow structure.

5. A multi-site adjustment reagent oscillator vortex instrument according to claim 1, characterized in that A support bearing is arranged between the transmission shaft and the support block.

6. A multi-site adjustment reagent shaker vortex according to claim 1, characterized in that The square plate is fixedly placed on the inner side surface of the U-shaped strip near one end.

7. A multi-site adjustment reagent shaker vortexer according to claim 1, characterized in that A support bearing is arranged between the threaded rod and the rotating cube.

8. A multi-site adjustment reagent oscillator vortex instrument according to claim 1, characterized in that The inner surface of the sliding groove is polished.

9. A multi-site adjustment reagent oscillating vortex instrument according to claim 1, characterized in that The adjusting handle adopts an ergonomic triangular prism structure and is provided with a rubber anti-slip sleeve on the surface.

10. A multi-site adjusting reagent oscillator vortex instrument according to claim 1, characterized in that The reagent tube holding device is integrally formed of elastic silica gel material.

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