A microfluidic chip detection device

Abstract

This invention discloses a microfluidic chip detection device, relating to the technical field of microfluidic chips. It includes a microfluidic chip body, a puncture component, and a limiting component. The microfluidic chip body has a cavity for placing a diluent sac, and a push handle is slidably connected within the cavity. The puncture component and the limiting component are respectively disposed within the push handle. This application uses an elastic sheet to position the push handle within the microfluidic chip body, preventing the push handle from sliding arbitrarily during transportation and transfer, which could cause crushing of the diluent sac. The outer end of the push handle extends precisely into the pressure groove of the push handle. The bending rod is bent at 90° to avoid pressure on the push handle. Simultaneously, the puncture piece retracts into the push handle under the action of a spring, preventing premature puncture of the diluent sac by contact with the puncture piece. A squeezing component positions the elastic sheet into an elastic limiting block, allowing the push handle to slide within the cavity while limiting the puncture piece extending from the push handle, facilitating subsequent puncture of the diluent sac.

Description

Technical Field

[0001] This invention relates to the technical field of microfluidic chips, and more specifically to a microfluidic chip detection device. Background Technology

[0002] Microfluidic chips are miniaturized technology platforms whose core principle is to achieve precise control of liquids through microscale fluid dynamics. They feature high integration, low sample consumption, rapid response, and high sensitivity. Some existing microfluidic chip detection devices require a puncture mechanism to puncture the diluent sac during use, allowing the diluent to flow into the reaction chamber of the microfluidic chip for detection experiments. However, since the puncture mechanism is encapsulated with the diluent sac, it is prone to puncture during transport by colliding with the puncture mechanism and the pushing component, causing premature leakage of the diluent and affecting subsequent detection results. Summary of the Invention

[0003] The purpose of this invention is to provide a microfluidic chip detection device to overcome the above-mentioned defects in the prior art.

[0004] A microfluidic chip detection device includes a microfluidic chip body, wherein the microfluidic chip body has a cavity for placing a diluent sac, and a push handle is slidably connected in the cavity, and further includes a puncture component and a limiting component.

[0005] The puncturing component is located in the push handle and punctures the diluent sac when the puncturing blade on it extends out of the push handle.

[0006] The limiting component is located in the push handle and is used to position the stationary push handle and to position the piercing blade extending from the push handle.

[0007] Preferably, the puncture assembly further includes a guide rod, a support plate, a spring, and a push rod. The guide rod is disposed between the inner wall of the push handle and the fixed block in the push handle. The support plate is slidably connected to the guide rod via a slider on its lower side. The puncture piece is disposed on the side of the support plate and extends out through a slot on the inner end of the push handle. The spring is sleeved on the guide rod and is used between the inner wall of the push handle and the slider. The push rod is slidably connected to the push handle and its inner end is connected to the support plate. The outer end of the push rod extends exactly into the pressure groove of the push handle.

[0008] Preferably, the limiting component includes an elastic sheet, a squeezing member, and a limiting block. The elastic sheet is disposed in the push handle and its two ends extend through the side holes on both sides of the push handle and are inserted into the positioning groove on the inner wall of the bladder cavity. The squeezing member is disposed on the side of the support plate. The limiting block is disposed on the inner wall of the push handle and is directly opposite to the squeezing member. The elastic sheet is located between the squeezing member and the limiting block.

[0009] Preferably, the extrusion member includes a vertical plate and a protrusion, the protrusion being connected to the support plate via the vertical plate, and the protrusion having a cylindrical structure.

[0010] Preferably, the limiting block is made of an elastic material, and the end of the limiting block is provided with a strip groove, which is connected to the limiting groove on the limiting block. The limiting groove is a cylindrical structure.

[0011] Preferably, the limiting block has symmetrical extrusion slopes on both sides of the strip groove.

[0012] Preferably, the support plate has an inverted "L" shaped structure.

[0013] Preferably, the outer end of the push rod is hinged to a bent rod via a pin.

[0014] The beneficial effects achieved by this invention are as follows:

[0015] 1. This application uses an elastic sheet to position the push handle in the microfluidic chip body, preventing the push handle from sliding randomly during transportation and transfer, which could cause the dilution fluid bladder to be squeezed and broken. The outer end of the push rod extends into the pressure groove of the push handle, and the bending rod is bent at 90° to avoid pressure on the push rod. At the same time, the puncture piece retracts into the push handle under the action of the spring force, preventing the puncture piece from contacting the dilution fluid bladder and puncturing it prematurely.

[0016] 2. This application uses an extruder to position the elastic sheet into an elastic limiting block, allowing the push handle to slide within the bladder cavity. At the same time, it limits the puncture piece extending from the push handle, facilitating subsequent puncture of the diluent bladder by the puncture piece. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the overall structure of the present invention.

[0018] Figure 2 This is a schematic diagram of the internal structure of the present invention.

[0019] Figure 3 This is a top view of the inside of the push handle of the present invention.

[0020] Figure 4 This is a schematic diagram of the internal structure of the push handle of the present invention.

[0021] Figure 5 This is a schematic diagram of the puncture component and the limiting component of the present invention.

[0022] Figure 6 for Figure 5 A magnified view of a portion of the image.

[0023] Figure 7 This is a schematic diagram of the structure of the limiting block of the present invention.

[0024] In the figure, 1 is the microfluidic chip body; 11 is the cyst cavity; 2 is the push handle; 3 is the puncture component; 31 is the puncture piece; 32 is the guide rod; 33 is the fixing block; 34 is the support plate; 35 is the slider; 36 is the spring; 37 is the push rod; 38 is the bending rod; 4 is the limiting component; 41 is the elastic sheet; 42 is the extrusion component; 421 is the vertical plate; 422 is the protrusion; 43 is the limiting block; 431 is the strip groove; 432 is the limiting groove; and 433 is the extrusion slope. Detailed Implementation

[0025] The following detailed description of the embodiments, with reference to the accompanying drawings, will further illustrate the specific implementation of the present invention, in order to help those skilled in the art to have a more complete, accurate, and in-depth understanding of the concept and technical solutions of the present invention.

[0026] like Figure 1-7 As shown, the present invention provides a microfluidic chip detection device, including a microfluidic chip body 1, wherein the microfluidic chip body 1 is provided with a cavity 11 for placing a diluent sac, and a push handle 2 is slidably connected in the cavity 11. The device is characterized in that it further includes a puncture component 3 and a limiting component 4.

[0027] Furthermore, the puncture assembly 3 is disposed in the push handle 2 and punctures the diluent bladder when the puncture piece 31 extends out of the push handle 2. The puncture assembly 3 also includes a guide rod 32, a support plate 34, a spring 36, and a push rod 37. The guide rod 32 is disposed between the inner wall of the push handle 2 and the fixing block 33 in the push handle 2. The support plate 34 has an inverted "L" shaped structure and is slidably connected to the guide rod 32 through the slider 35 on its lower side. The puncture piece 31 is disposed on the side of the support plate 34 and extends out through the slot on the inner end of the push handle 2. The spring 36 is sleeved on the guide rod 32 and is used between the inner wall of the push handle 2 and the slider 35.

[0028] The push rod 37 is slidably connected to the push handle 2 and its inner end is connected to the support plate 34. The outer end of the push rod 37 extends into the pressure groove of the push handle 2. The outer end of the push rod 37 is hinged to a bent rod 38 by a pin. After the bent rod 38 rotates 90°, it can press the push rod 37 to move, so that the puncture piece 31 extends out of the push handle 2.

[0029] Additionally, the limiting component 4 is disposed in the push handle 2 and is used to position the stationary push handle 2 and the puncture piece 31 extending out of the push handle 2. The limiting component 4 includes an elastic sheet 41, a squeezing member 42, and a limiting block 43. The elastic sheet 41 is disposed in the push handle 2, and its two ends extend through the side holes on both sides of the push handle 2 and are inserted into the positioning groove on the inner wall of the cyst cavity 11. The squeezing member 42 is disposed on the side of the support plate 34. The squeezing member 42 includes a vertical plate 421 and a protrusion 422. The protrusion 422 is connected to the support plate 34 through the vertical plate 421. The protrusion 422 is... The cylindrical structure has a limiting block 43 located on the inner wall of the push handle 2 and facing the extruder 42. The elastic sheet 41 is located between the extruder 42 and the limiting block 43. The limiting block 43 is made of elastic material. The end of the limiting block 43 is provided with a strip groove 431, which communicates with the limiting groove 432 on the limiting block 43. The limiting block 43 has symmetrical extrusion inclined surfaces 433 on both sides of the strip groove 431, which makes it easier for the protrusion 422 of the extruder 42 to drive the elastic sheet 41 into the limiting groove 432 for positioning. The limiting groove 432 is a cylindrical structure.

[0030] Detailed implementation methods and principles:

[0031] When the microfluidic chip body 1 is not working, the two ends of the elastic sheet 41 extend through the side holes on both sides of the push handle 2 and are inserted into the positioning groove on the inner wall of the bladder cavity 11 to position the push handle 2 in the microfluidic chip body 1. At the same time, under the elastic force of the spring 36 on the guide rod 32, the puncture piece 31 is retracted into the push handle 2 to avoid the puncture piece 31 from contacting the diluent bladder and puncturing it in advance.

[0032] When the microfluidic chip body 1 needs to operate, the operator holds the push handle 2 with one hand and rotates the bending rod 38 90° with the other hand to align it with the push rod 37. Then, the bending rod 38 pushes the push rod 37 to move, causing the slider 35 on the support plate 34 to move along the guide rod 32. The piercing piece 31 gradually extends out of the push handle 2. During the movement of the support plate 34, the pressing element 42 on the support plate 34 presses the elastic piece 41, thereby causing the elastic piece 41 to disengage from the positioning groove on the inner wall of the microfluidic chip body 1. The protrusion 422 drives the elastic sheet 41 through the strip groove 431 on the limiting block 43 into the limiting groove 432. Since the limiting block 43 is made of elastic material, the limiting block 43 deforms to clamp and fix the extrusion part 42 and the elastic sheet 41. At this time, the piercing piece 31 extends out of the push handle 2, and the two ends of the elastic sheet 41 are respectively located in the side holes on both sides of the push handle 2. Then push the push handle 2, and pierce the diluent bladder through the piercing piece 31, so that the diluent in the diluent bladder flows into the reaction chamber of the microfluidic chip body 1 for corresponding detection experiments.

[0033] The embodiments of the present invention described above do not constitute a limitation on the scope of protection of the present invention. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention should be included within the scope of protection of the claims of the present invention.

Claims

1. A microfluidic chip detection device, comprising a microfluidic chip body (1), wherein the microfluidic chip body (1) is provided with a cavity (11) for placing a diluent capsule, and a push handle (2) is slidably connected in the cavity (11), characterized in that: It also includes a puncture component (3) and a limiting component (4); The puncture component (3) is located in the push handle (2) and punctures the diluent sac when the puncture piece (31) extends out of the push handle (2); The puncture assembly (3) also includes a guide rod (32), a support plate (34), a spring (36), and a push rod (37). The guide rod (32) is located between the inner wall of the push handle (2) and the fixing block (33) in the push handle (2). The support plate (34) is slidably connected to the guide rod (32) through the slider (35) on its lower side. The puncture piece (31) is located on the side of the support plate (34) and extends out through the slot on the inner end of the push handle (2). The spring (36) is sleeved on the guide rod (32) and located between the inner wall of the push handle (2) and the slider (35). Under the elastic force of the spring (36), the puncture piece (31) is retracted into the push handle (2). The push rod (37) is slidably connected to the push handle (2) and its inner end is connected to the support plate (34). The outer end of the push rod (37) extends into the pressure groove of the push handle (2). The limiting component (4) is located in the push handle (2) and includes an elastic sheet (41), a squeezing member (42) and a limiting block (43). The elastic sheet (41) is located in the push handle (2) and its two ends extend through the side holes on both sides of the push handle (2) and are inserted into the positioning groove on the inner wall of the bladder cavity (11) and are used to position the push handle (2) when it is not moved. The squeezing member (42) is located on the side of the support plate (34). The limiting block (43) is located on the inner wall of the push handle (2) and is directly opposite to the squeezing member (42). The elastic sheet (41) is located between the squeezing member (42) and the limiting block (43). The extrusion member (42) includes a vertical plate (421) and a protrusion (422). The protrusion (422) is connected to the support plate (34) through the vertical plate (421). The protrusion (422) has a cylindrical structure. The limiting block (43) is made of elastic material. The end of the limiting block (43) is provided with a strip groove (431). The strip groove (431) is connected to the limiting groove (432) on the limiting block (43). The limiting groove (432) is a cylindrical structure. When the microfluidic chip body (1) is working, during the movement of the support plate (34), the puncture piece (31) gradually extends out from the push handle (2). The extrusion piece (42) on the support plate (34) presses the elastic piece (41), causing the elastic piece (41) to detach from the positioning groove on the inner wall of the microfluidic chip body (1). The protrusion (422) of the extrusion piece (42) drives the elastic piece (41) through the strip groove (431) on the limiting block (43) into the limiting groove (432), causing the limiting block (43) to deform and clamp and fix the extrusion piece (42) and the elastic piece (41), thereby positioning the puncture piece (31) extending out of the push handle (2). At this time, the puncture piece (31) completes to extend out of the push handle (2), and the two ends of the elastic piece (41) are respectively located in the side holes on both sides of the push handle (2). Then push the push handle (2) to puncture the diluent bladder through the puncture piece (31).

2. The microfluidic chip detection device according to claim 1, characterized in that: The limiting block (43) has symmetrical extrusion inclined surfaces (433) on both sides of the strip groove (431).

3. The microfluidic chip detection device according to claim 1, characterized in that: The support plate (34) has an inverted "L" shaped structure.

4. The microfluidic chip detection device according to claim 1, characterized in that: The outer end of the push rod (37) is hinged to a bent rod (38) via a pin.

Images