Ascites concentration filtration and reinfusion system

Abstract

The present invention discloses an ascites concentration, filtration and reinfusion system, comprising an ascites drainage pipeline, a filter, a plasma component separator and a reinfusion peritoneal pipeline. The ascites drainage pipeline is connected to the inlet of the filter for conveying the ascites to be treated, the liquid outlet of the filter is connected to the inlet of the plasma component separator through a first infusion pipeline, the plasma component separator is used to separate and remove harmful components in the concentrated ascites, and the bypass side port of the plasma component separator is connected to the reinfusion peritoneal pipeline to reinfuse the treated ascites into the peritoneal cavity. The present invention has multiple intervention treatment principles and multi-path individualized switching combinations, significantly improving the efficiency of removing harmful substances in ascites, while retaining and purifying macromolecular beneficial or nutrient substances such as albumin; and then using the peritoneal greater omentum capillary network for slow absorption, avoiding the risks and high costs of complications of intravenous reinfusion after treatment, hemodynamics are stable, and the entire treatment system is safer.

Description

Technical Field

[0001] The present invention relates to the technical field of medical equipment consumables, and in particular to an ascites concentration, filtration and reinfusion system. Background Art

[0002] Ascites is a common complication of end-stage liver disease (including cirrhosis, liver cancer and liver failure). Its formation involves multiple pathological mechanisms, mainly including the synergistic effects of portal hypertension, hypoproteinemia, malnutrition and inflammatory response.

[0003] Currently, traditional treatments for ascites include sodium restriction, diuretics, paracentesis, simple ascites ultrafiltration, concentration, and reinfusion, TIPS, and liver transplantation. However, all of these methods have limitations, including high recurrence of ascites after treatment, poor compliance, numerous complications, high costs, and limited liver supply. Existing simple ascites ultrafiltration, concentration, and reinfusion systems often rely solely on ultrafiltration to remove water, effectively removing only fluid but failing to adequately remove harmful substances such as broken cells, fibrous tissue, bacteria, cancer cells, and endotoxins from the ascites. This can lead to the concentration of these harmful substances and reinfusion into the peritoneal cavity, creating a fertile breeding ground for pathogens and exacerbating the deterioration of the intraperitoneal environment. Furthermore, these concentrated harmful substances may be absorbed by the peritoneal omental capillary network, creating a vicious cycle of environmental degradation. These technical limitations make existing methods difficult to meet the personalized treatment needs of specialized types of ascites, such as infectious, chylous, and cancerous ascites. Furthermore, simple ascites ultrafiltration, concentration, and reinfusion systems often feature complex and easily kinked tubing, making operation more difficult and increasing the risk of nosocomial infection.

[0004] Therefore, a new ascites concentration, filtration and reinfusion system is urgently needed to solve the above technical problems. Summary of the Invention

[0005] The present invention aims to solve the above-mentioned technical problems, namely, to solve the problem that the existing ascites filtration only achieves liquid removal but fails to fully remove harmful substances such as broken cell components, fibrous tissue, bacteria, cancer cells, endotoxins, etc. in the ascites, which may result in these harmful substances being concentrated and then reinfused into the abdominal cavity, which not only creates a good potential environment for the growth of pathogens and aggravates the deterioration of the intra-abdominal environment; moreover, these concentrated harmful substances may be absorbed by the peritoneal omentum capillary network, causing a vicious cycle problem in the internal environment, as well as the problem that the pipelines in the simple ascites ultrafiltration concentration and reinfusion system are arranged in a messy manner and are easily folded, which increases the difficulty of operation and also increases the risk of hospital infection.

[0006] To this end, the present invention provides an ascites concentration, filtration and reinfusion system, comprising an ascites drainage line, a filter, a plasma component separator and a peritoneal cavity reinfusion line, wherein the ascites drainage line is connected to the filter inlet for transporting ascites to be treated, the filter is used to filter and concentrate the ascites to be treated, the filter outlet is connected to the plasma component separator inlet via a first infusion line, the plasma component separator is used to separate and remove harmful components in the concentrated ascites, the bypass side port of the plasma component separator is connected to the peritoneal cavity reinfusion line to reinfuse the treated ascites into the peritoneal cavity, and a first tube pump is installed on both the ascites drainage line and the peritoneal cavity reinfusion line.

[0007] In a specific embodiment of the above-mentioned ascites concentration, filtration and reinfusion system, the ascites concentration, filtration and reinfusion system also includes a blood adsorber and two second infusion lines, one end of one second infusion line is connected to the first infusion line, and the other end is connected to the inlet of the blood adsorber, one end of the other second infusion line is connected to the outlet of the blood adsorber, and the other end is connected to the first infusion line, and line clamps are installed on the two second infusion lines, the first infusion line between the two second infusion lines, the ascites drainage line and the peritoneal cavity reinfusion line.

[0008] In a specific embodiment of the above-mentioned ascites concentration, filtration and reinfusion system, the ascites concentration, filtration and reinfusion system further includes an integrated panel, and the ascites drainage line, the first infusion line and the peritoneal cavity reinfusion line are all clipped onto the integrated panel according to a set path.

[0009] In a specific embodiment of the above-mentioned ascites concentration, filtration and reinfusion system, the ascites drainage line, the first infusion line and the peritoneal cavity reinfusion line are all provided with liquid collection pots, and the integrated panel is provided with multiple first card slots and multiple second card slots. The ascites drainage line, the first infusion line and the peritoneal cavity reinfusion line are all clamped on the integrated panel through the first card slots, and the liquid collection pot is clamped on the integrated panel through the second card slots.

[0010] In a specific embodiment of the above-mentioned ascites concentration, filtration and reinfusion system, the waste liquid port of the plasma component separator is connected to a waste liquid collection bag, and the ascites concentration, filtration and reinfusion system also includes a waste liquid recirculation filtration pipeline, one end of the waste liquid recirculation filtration pipeline is connected to the waste liquid collection bag, and the other end is connected to the inlet port of the plasma component separator, and a second tube pump is installed on the waste liquid recirculation filtration pipeline.

[0011] In a specific embodiment of the above-mentioned ascites concentration, filtration and reinfusion system, the filter is a blood filter.

[0012] In a specific embodiment of the above-mentioned ascites concentration, filtration and reinfusion system, the filter is a hemodialyzer.

[0013] In a specific embodiment of the above-mentioned ascites concentration, filtration and reinfusion system, the liquid collection pot is provided with an external discharge port and is connected to a pressure monitor, a line clamp is installed on the external discharge port, and the pressure monitor is clamped on the integrated panel.

[0014] In a specific embodiment of the above-mentioned ascites concentration, filtration and reinfusion system, the filter and the plasma component separator are both connected to a transmembrane pressure detector, and a side outlet is provided on the ascites drainage pipeline, and the side outlet is connected to a PVC intra-abdominal pressure detection pipeline with a scale.

[0015] In a specific embodiment of the above-mentioned ascites concentration, filtration and re-infusion system, the waste liquid port of the filter is connected to the ultrafiltrate collection bag through the ascites ultrafiltration line, a third tube pump is installed on the ascites ultrafiltration line, and the ultrafiltrate collection bag and the waste liquid collection bag are both connected to a liquid measuring scale with an LED display.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] 1. The present invention has a multi-intervention treatment principle and a multi-path individualized switching combination, that is, according to the type of ascites, the combination of a blood filter / hemodialyzer and a plasma component separator is individually selected to be combined with a blood adsorber, which significantly improves the efficiency of removing harmful substances in ascites, while retaining and purifying large molecules of beneficial or nutritious substances such as albumin; after treatment, it is slowly absorbed by the peritoneal omentum capillary network, avoiding the risks and high costs of complications of intravenous reinfusion after treatment, and the hemodynamics are stable. The entire treatment system is safer, more convenient, and more efficient, with good patient compliance and feedback, strong operation repeatability, and easy promotion and application of the technology.

[0018] 2. The present invention integrates multiple pipelines on an integrated panel according to set paths, preventing the pipelines from being bent, facilitating rapid deployment at the bedside, and facilitating monitoring of the treatment process, improving convenience, installation and removal efficiency, reducing the risk of hospital infection, and improving the safety of treatment.

[0019] 3. By setting up a PVC intra-abdominal pressure detection pipeline with a scale, the changes in intra-abdominal pressure can be directly and more accurately monitored dynamically, which is beneficial for evaluating clinical efficacy. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The preferred embodiments of the present invention are described below with reference to the accompanying drawings, in which:

[0021] Figure 1 This is a schematic diagram of the overall structure of the ascites concentration, filtration and reinfusion system provided by the present invention;

[0022] Figure 2 yes Figure 1 A schematic structural diagram of the first card slot;

[0023] Figure 3 yes Figure 1 Schematic diagram of the structure of the second card slot.

[0024] List of reference numerals:

[0025] 1. Filter; 2. Blood adsorber; 3. Plasma component separator; 4. First tube pump; 5. Transmembrane pressure detector; 6. Liquid collection pot; 7. Line clamp; 8. Ultrafiltrate collection bag; 9. Waste liquid collection bag; 10. Third tube pump; 11. Pressure monitor; 12. Liquid measuring scale with LED display; 13. Drainage ascites pipeline; 14. Ascites ultrafiltration pipeline; 15. First infusion line; 16. Second infusion line; 17. Third infusion line; 18. Waste liquid recirculation filtration line; 19. Return to the peritoneal cavity pipeline; 20. Scientific research specimen interface; 21. Connecting part; 22. Pre-pump pre-filling pipeline; 23. Second card slot; 24. First card slot; 25. Second tube pump; 26. Integrated panel; 27. PVC intra-abdominal pressure detection pipeline with scale. DETAILED DESCRIPTION

[0026] To make the objectives, technical solutions, and advantages of the present invention more clear, the technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the embodiments described are only some of the embodiments of the present invention, not all of them. All other embodiments derived by persons of ordinary skill in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0027] In the description of the present invention, it should be noted that the terms "upper," "lower," "inner," and "outer," etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings and are intended solely to facilitate description and simplify the present invention. They are not intended to indicate or imply that the systems or components referred to must have, be constructed, or operate in a specific orientation, and therefore should not be construed as limitations on the present invention. Furthermore, the use of terms such as "first" and "second" to define components is intended solely to facilitate distinction between such components. Unless otherwise stated, these terms have no special meanings and should not be construed as indicating or implying relative importance.

[0028] In the description of the present invention, it should be noted that, unless otherwise expressly specified or limited, the terms "installed," "installed," and "connected" should be understood in a broad sense. For example, they may refer to fixed, detachable, or integral connections; mechanical or electrical connections; direct or indirect connections through an intermediate medium; and internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in the present invention based on the specific circumstances.

[0029] The present invention relates to the technical field of medical equipment and consumables, and in particular to an ascites concentration, filtration and reinfusion system. The purpose is to solve the problem that although the existing single ascites ultrafiltration technology can quickly remove water from ascites to a certain extent, it has the problems of low filtration efficiency, long treatment cycle, insufficient removal of harmful substances, and is not suitable for infectious and cancerous ascites. To this end, the ascites concentrated filtration and reinfusion system (ACFRS) provided by the present invention includes an ascites drainage pipeline, a filter, a plasma component separator and a peritoneal cavity reinfusion pipeline, the ascites drainage pipeline is connected to the inlet of the filter for transporting ascites to be treated, the filter is used to filter and concentrate the ascites to be treated, the liquid outlet of the filter is connected to the inlet of the plasma component separator through the first infusion pipeline, the plasma component separator is used to separate and remove harmful components in the concentrated ascites, the bypass side port of the plasma component separator is connected to the peritoneal cavity reinfusion pipeline to reinfuse the treated ascites into the peritoneal cavity, and the ascites drainage pipeline is connected to the inlet of the plasma component separator through the first infusion pipeline. The plasma component separator is used to separate and remove harmful components in the concentrated ascites. The bypass side port of the plasma component separator is connected to the peritoneal cavity reinfusion pipeline to reinfuse the treated ascites into the peritoneal cavity. A first tube pump is installed on both the pipeline and the return-to-abdominal pipeline. The present invention can individually select a hemodialyzer or a hemofilter according to the properties of the ascites to remove excess water and other harmful small and medium-molecule substances, and then slowly pass through a plasma component separator to remove harmful components such as endotoxins, bacteria, broken red blood cells and fibrous tissue, and larger particles of impurities. Finally, the treated liquid containing beneficial substances (albumin, etc.) is returned to the patient's body and slowly absorbed through the greater omentum of the peritoneal cavity, thereby achieving effective removal of harmful components in the ascites and retention of beneficial components in the overall sense, ensuring the stability and safety of the returned components.

[0030] The ascites concentration, filtration and reinfusion system provided by the embodiment of the present invention will be described in detail below with reference to the accompanying drawings.

[0031] See Figure 1The present invention provides an ascites concentrated filtration and reinfusion system (ACFRS), comprising an ascites drainage line 13, a filter 1, a plasma component separator 3, and a peritoneal cavity reinfusion line 19. The ascites drainage line 13 is connected to the inlet of the filter 1 for conveying ascites to be treated. The filter 1 is used to filter and concentrate the ascites to be treated. The liquid outlet of the filter 1 is connected to the inlet of the plasma component separator 3 through a first infusion line 15. The plasma component separator 3 is used to separate and remove harmful components in the concentrated ascites. The bypass side port of the plasma component separator 3 is connected to the peritoneal cavity reinfusion line 19 to reinfuse the treated ascites into the peritoneal cavity. A first tube pump 4 is installed on both the ascites drainage line 13 and the peritoneal cavity reinfusion line 19.

[0032] In the above embodiment, the filter 1 is a hemofilter or hemodialyzer, selected individually based on the properties of the ascites. The first tube pump 4 can be a peristaltic pump. Both the filter 1 and the plasma separator 3 are connected to a transmembrane pressure detector 5 for detecting transmembrane pressure and adjusting flow rate based on pressure to prevent clogging and damage to the filter 1 and plasma separator 3.

[0033] In the above embodiment, a line clamp 7 is installed on both the ascites drainage line 13 and the return-to-abdominal line 19. A pre-pump priming line 22 is installed between the line clamp 7 and the first tube pump 4 to clear the entire line before ascites treatment. The ascites drainage line 13 is provided with a side outlet, which is connected to a PVC intra-abdominal pressure detection line 27 with a scale. Specifically, a three-way tube is provided on the ascites drainage line between the line clamp and the pre-pump priming line, and one end of the three-way tube is a side outlet. By providing a PVC intra-abdominal pressure detection line with a scale, the changes in the intra-abdominal pressure can be directly and more accurately monitored dynamically, which is beneficial for evaluating the clinical efficacy.

[0034] The ascites drainage line 13, the first infusion line 15 and the peritoneal cavity return line 19 are all provided with a liquid collection pot 6, the liquid collection pot 6 is provided with an external discharge port and is connected to a pressure monitor 11 and the external discharge port, and a line clamp 7 is installed on the external discharge port.

[0035] In addition, the drainage ascites pipeline 13 and the inlet of the filter 1, the first infusion pipeline 15 and the outlet of the filter 1, the inlet of the plasma component separator 3 and the first infusion pipeline 15, and the outlet and the return peritoneal cavity pipeline 19 can all be disassembled, which is convenient for replacement.

[0036] In one embodiment, continue to refer to Figure 1The ascites concentration, filtration and reinfusion system also includes a blood adsorber 2 and two second infusion lines 16, one end of one second infusion line 16 is connected to the first infusion line 15, and the other end is connected to the inlet of the blood adsorber 2, and one end of the other second infusion line 16 is connected to the outlet of the blood adsorber 2, and the other end is connected to the first infusion line 15. Line clamps 7 are installed on the two second infusion lines 16 and on the first infusion line 15 between the two second infusion lines 16.

[0037] In the above embodiment, whether to combine the hemofilter / hemodialyzer and the plasma component separator 3 with the hemoadsorber 2 is individually selected.

[0038] In one embodiment, see Figure 1 The waste liquid port of the plasma component separator 3 is connected to the waste liquid collection bag 9 via a third infusion line 17. The ascites concentration, filtration and reinfusion system further includes a waste liquid recirculation filtration line 18. One end of the waste liquid recirculation filtration line 18 is connected to the waste liquid collection bag 9, and the other end is connected to the inlet of the plasma component separator 3. A second tube pump 25 is installed on the waste liquid recirculation filtration line 18. The second tube pump 25 can be a peristaltic pump.

[0039] The specific working process of this application is as follows: the ascites to be purified is transported to the filter 1 through the first tube pump 4 on the ascites drainage line 13, and the ascites is ultrafiltered through the filter 1 (hemofilter or hemodialyzer) to remove inflammatory factors and harmful small molecules in the ascites, and at the same time, the excess water is removed by ultrafiltration concentration, and then the filtered and concentrated ascites flows into the first infusion line 15 through the liquid outlet of the filter 1, and then directly enters the plasma component separator 3 or enters the blood adsorber 2 and then enters the plasma component separator. 3, for example, first enters the hemoadsorber 2, where the filtered and concentrated ascites undergoes secondary purification. The hemoadsorber 2 removes potential medium and large molecular harmful substances through broad-spectrum adsorption; the secondary purified ascites enters the plasma component separator 3 through the first infusion line 15 to complete a third purification, removing harmful components such as broken cell components, fibrous tissue, bacteria, cancer cells, and endotoxins from the ascites after ultrafiltration, concentration, and adsorption. The ascites is then returned to the peritoneal cavity through the return peritoneal cavity line 19, where it is slowly absorbed by the vast capillary network in the greater omentum. The waste liquid entering the waste liquid collection bag 9 can be recirculated and filtered and separated through the recirculation line, which helps to filter the waste liquid again and reduce the loss of beneficial components.

[0040] This application uses a multi-stage membrane combined with adsorption materials to remove endotoxins, bacteria, broken cells, and macromolecular toxins while maximally retaining nutrients such as albumin. Dynamically select a combination of ultrafiltration, adsorption, filtration, and cell separation based on the type of ascites for higher efficiency.

[0041] In one embodiment, the ascites concentration, filtration and reinfusion system further comprises an integrated panel 26, on which the ascites drainage line 13, the first infusion line 15 and the peritoneal cavity reinfusion line 19 are all clipped according to the set paths. Regarding the set paths, this application does not make any specific restrictions. For example, Figure 1 The specific arrangement of the pipelines shown can be flexibly set according to the actual use scenario. Multiple pipelines are integrated on the integrated panel 26 according to the set path, preventing pipeline folding, facilitating rapid deployment at the bedside, and facilitating monitoring of the treatment process. This improves convenience, installation and removal efficiency, reduces the risk of nosocomial infection, and improves treatment safety.

[0042] Specifically, the integrated panel 26 is provided with a plurality of first slots 24 and a plurality of second slots 23. The ascites drainage line 13, the first infusion line 15, and the peritoneal cavity return line 19 are all clipped onto the integrated panel 26 through the first slots 24, and the liquid collection pot 6 and the pressure monitor are both clipped onto the integrated panel 26 through the second slots 23. The integrated panel 26 is provided with a connection portion 21 for fixing the panel. For example, the connection portion 21 is a slot structure. When in use, the integrated panel 26 is clipped into a specified position to ensure that the integrated panel 26 is fixed during use. The number and arrangement of the first slots 24 and the second slots 23 are not specifically limited in this application and can be flexibly set according to actual usage.

[0043] More specifically, see Figure 2 and Figure 3 The first and second slots 24, 23 are both annular in shape, and a notch is provided on the first and second slots 24, 23 to facilitate insertion of the corresponding pipeline into the first slot 24 and the liquid collection pot 6 into the second slot 23. This snap-fit ​​connection of the pipeline and the liquid collection pot 6 to the integrated panel 26 is convenient for installation and removal, simple to operate, and improves replacement efficiency.

[0044] In one embodiment, the waste liquid port of the filter 1 is connected to the ultrafiltrate collection bag 8 via an ascites ultrafiltration line 14. A third tube pump 10 is installed on the ascites ultrafiltration line 14. The ultrafiltrate collection bag 8 and the waste liquid collection bag 9 are both connected to a liquid measuring scale 12 with an LED display. The third tube pump 10 can be a peristaltic pump.

[0045] In this application, a liquid weighing scale 12 with an LED display can weigh the liquid in the ultrafiltrate collection bag 8 and the waste liquid collection bag 9. A scientific specimen interface 20 is provided on the ascites drainage line 13, the first infusion line 15, and the return to the peritoneal cavity line 19, for future applications such as improving the positive rate of microbial culture, drug sensitivity testing, and tumor gene vaccine development.

[0046] This application utilizes a hemofilter / hemodialyzer and plasma fractionator, individually selecting whether to incorporate a hemoadsorber to remove excess water and other harmful small and medium-molecule substances. The fluid then slowly passes through the plasma fractionator to remove harmful components such as endotoxins, bacteria, fragmented red blood cells and fibrous tissue, and larger impurities. The treated fluid, containing beneficial substances (such as albumin), is then reinfused into the patient for slow absorption through the greater omentum. This effectively removes harmful components from the ascites while retaining beneficial components. The purified albumin and other beneficial substances are slowly absorbed during reinfusion, promoting improvements in nutrition and immunity, forming a virtuous cycle and ensuring the stability and safety of the reinfused components. Compared to traditional single ultrafiltration systems, this technology offers significant advantages, including improved patient compliance, reduced recurrence rates, and significantly lower medical costs. This intraperitoneal-to-interperitoneal reinfusion is safer, improves patient compliance, and offers greater repeatability. It achieves high and rapid ascites removal per treatment, significantly improves abdominal distension symptoms, and significantly improves sleep and diet, while avoiding adverse reactions associated with intravenous reinfusion.

[0047] Traditionally, treatments for ascites have primarily included sodium restriction, diuretic therapy, paracentesis, liver transplantation, and bypass surgery. These methods can alleviate ascites symptoms to a certain extent, but they have numerous drawbacks. Sodium restriction and diuretic therapy play a role in the early treatment of ascites, but are less effective for refractory ascites and are often associated with side effects such as electrolyte imbalance. While paracentesis can rapidly reduce intraperitoneal pressure and alleviate symptoms, it requires frequent procedures, carries the risk of infection, and can lead to complications such as hypotension and renal impairment. Furthermore, paracentesis cannot effectively prevent the recurrence of ascites. Traditional single-use ultrafiltration systems, when treating ascites, fail to remove harmful substances (such as fibrous tissue, broken cells, and large toxins). Instead, they concentrate these substances and reinfuse them, increasing the risk of infection and compromising treatment effectiveness.

[0048] However, the plasma component separator designed in this invention can remove harmful components from ascites, such as endotoxins, bacteria, broken red blood cells and fibrous tissue, and larger impurities, thereby improving the intra-abdominal environment. Ultimately, the treated fluid, containing beneficial substances (such as albumin), is returned to the patient's body for slow absorption through the greater omentum, promoting improvements in nutrition and immunity, forming a virtuous cycle and achieving a new balance between retaining beneficial substances and removing toxins. Commonly used plasma component separators include Evacure EC-2A, 3A, and 4A, with membrane pore sizes of 0.01μm, 0.02μm, and 0.03μm, respectively, and albumin sieving coefficients of 0.25, 0.65, and 0.75, respectively. The type of plasma component separator should be selected based on actual conditions.

[0049] The ascites concentration, filtration, and reinfusion system designed in this invention can be used not only for transudative ascites, but also for infectious ascites, chylous ascites, and cancerous ascites. Slow treatment and cyclic reinfusion allow for a gradual decrease in intra-abdominal pressure, with minimal impact on hemodynamics. Furthermore, a single treatment clears a significant amount of ascites, significantly improving abdominal distension and related sleep and diet. Direct intra-abdominal pressure monitoring can be performed simultaneously or intermittently during each treatment, accurately quantifying the immediate and dynamic therapeutic effects.

[0050] The concentrated waste liquid in the present invention can also be used in research such as microbial culture, drug sensitivity testing, and tumor vaccine development; after the ascites is removed, it is beneficial to clinical digestive endoscopy, abdominal MRI / CT / B-ultrasound examinations; after the concentrated liquid such as waste water and waste cells is measured, combined with the daily intake and output, synchronous or intermittent direct intra-abdominal pressure monitoring during each treatment process is beneficial to the weight efficacy and weight management of patients with end-stage liver disease and refractory ascites.

[0051] The present invention is significantly superior to existing ascites treatment systems in terms of structural design, optimization of treatment principles, treatment pathways, safety mechanisms and reuse value. It not only further enhances the treatment effect on the basis of safety, but also has a wide range of adaptability, reasonable price, good patient compliance and feedback, strong operational repeatability, and easy technology promotion and application. The present invention has made systematic expansion in creativity and application volume, and has significant industrial transformation prospects and good social benefits.

[0052] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the protection scope of the technical solutions of the various embodiments of the present invention.

Claims

1. An ascites concentration, filtration and reinfusion system, characterized in that: The ascites drainage line comprises an ascites drainage line, a filter, a plasma component separator and a return to peritoneal cavity line, wherein the ascites drainage line is connected to the inlet of the filter for conveying the ascites to be treated, the filter is used to filter and concentrate the ascites to be treated, the outlet of the filter is connected to the inlet of the plasma component separator through a first infusion line, the plasma component separator is used to separate and remove harmful components in the concentrated ascites, the bypass side port of the plasma component separator is connected to the return to peritoneal cavity line to return the treated ascites to the peritoneal cavity, the ascites drainage line and the return to peritoneal cavity line are both equipped with a first tube pump, the ascites concentration, filtration and return system also comprises a blood adsorber and two second infusion lines, one end of one second infusion line is connected to the first infusion line, and the other end is connected to the inlet of the blood adsorber, one end of another second infusion line is connected to the outlet of the blood adsorber, and the other end is connected to the first infusion line, the two second infusion lines and the two second infusion lines are connected to the blood adsorber. The first infusion line, the drainage ascites line and the return to the peritoneal cavity line between the pipelines are all installed with line clamps. The ascites concentration, filtration and return system also includes an integrated panel. The drainage ascites line, the first infusion line, the second infusion line and the return to the peritoneal cavity line are all clamped on the integrated panel according to the set path. The drainage ascites line, the first infusion line and the return to the peritoneal cavity line are all provided with a liquid collection pot. The integrated panel is provided with a plurality of first card slots and a plurality of second card slots. The drainage ascites line The first infusion line, the second infusion line and the peritoneal cavity return line are all clamped on the integrated panel through the first card slot, the liquid collection pot is clamped on the integrated panel through the second card slot, the waste liquid port of the plasma component separator is connected to the waste liquid collection bag, and the ascites concentration filtration and return system also includes a waste liquid recycling filtration line, one end of the waste liquid recycling filtration line is connected to the waste liquid collection bag, and the other end is connected to the inlet of the plasma component separator, and a second tube pump is installed on the waste liquid recycling filtration line.

2. The ascites concentration, filtration and reinfusion system according to claim 1, characterized in that: The filter is a blood filter.

3. The ascites concentration, filtration and reinfusion system according to claim 1, characterized in that: The filter is a hemodialyzer.

4. The ascites concentration, filtration and reinfusion system according to claim 1, characterized in that: The liquid collecting pot is provided with an external discharge port and is connected to a pressure monitor. A line clamp is installed on the external discharge port, and the pressure monitor is clamped on the integrated panel.

5. The ascites concentration, filtration and reinfusion system according to claim 1, characterized in that: The filter and the plasma component separator are both connected to a transmembrane pressure detector, and the ascites drainage pipeline is provided with a side outlet, which is connected to a PVC intra-abdominal pressure detection pipeline with a scale.

6. The ascites concentration, filtration and reinfusion system according to claim 1, characterized in that: The waste liquid port of the filter is connected to an ultrafiltrate collection bag through an ascites ultrafiltration pipeline, a third tube pump is installed on the ascites ultrafiltration pipeline, and the ultrafiltrate collection bag and the waste liquid collection bag are both connected to a liquid metering scale with an LED display.

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