Molecular marker related to eggshell thickness and application thereof

Through SNP molecular marker detection related to the thickness of egg shells, individuals with different egg shell thickness were screened using genomic information, which solved the problem of high damage rate caused by thin egg shells in the late stage of egg laying, and improved breeding efficiency and accuracy.

CN120464746APending Publication Date: 2025-08-12INSTITUTE OF ANIMAL SCIENCES OF CHINESE ACADEMY OF AGRICULTURAL SCIENCES
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Patent Information

Application Number
CN202510475464.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-16
Publication Date
2025-08-12

AI Technical Summary

Technical Problem

In the prior art, the thickness of egg shells decreases in the late stage of egg laying, resulting in an increase in the damage rate. Conventional breeding methods are inefficient and have a long cycle, making it difficult to achieve rapid and accurate genetic improvement.

Method used

Using SNP molecular markers related to egg shell thickness, the polymorphic form T or C of the 35996365 site of chromosome 35996365 of the ENSEMBL chicken reference genome Gallus_gallos 7.0_W version sequence information chromosome 3 was designed to perform genotype detection, and individuals with large, medium and small egg shell thickness were screened for breeding selection.

Benefits of technology

It has achieved accurate screening of egg shell thickness at the genetic level, significantly improved breeding efficiency and accuracy, and promoted the development of breeding chicken breeding.

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Abstract

The invention relates to the technical field of livestock and poultry breeding, and discloses a molecular marker related to the thickness of an egg shell and application of the molecular marker. According to the molecular marker related to the eggshell thickness, the molecular marker is the 35996365th site from the 5'terminal on the No.3 chromosome of chicken reference genome Galusgallus 7.0 W version sequence information published in ENSEMBL, and the polymorphic form is T or C. According to the SNP molecular marker related to the eggshell thickness, the eggshell thickness can be bred on the gene level, the eggshell thickness is directly screened from the source, genetic information is accurately grasped, the defects of a traditional method are effectively overcome, the breeding efficiency and accuracy are remarkably improved, and the method is suitable for large-scale popularization and application. The method can be applied to breeding hen breeding practice in large scale to promote industrial development.
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