Efficient insecticidal active material containing indoxacarb molecular structure and preparation method thereof

Abstract

The invention discloses an efficient insecticidal active material containing an indoxacarb molecular structure, an active compound containing the indoxacarb molecular structure is formed by compounding indoxacarb and salicylic acid or phthalic acid, and the structure of the active compound containing the indoxacarb molecular structure is shown as a formula 1 or a formula 2; the organic salt of indoxacarb salicylate or indoxacarb phthalate can improve the stress resistance of plants, and meanwhile, the insecticidal activity of indoxacarb can be further improved; the preparation method comprises the following steps: mixing a photodegradation accelerator with a sodium alginate aqueous solution, and coating the photodegradation accelerator; according to the invention, the iron-based metal organic framework material is used as a carrier and is loaded with the active compound containing the indoxacarb molecular structure, and then the carrier and the coating photodegradation accelerant are coated in the sulfonic acid modified sodium alginate together, so that the stability and the drug loading rate of pesticide particles and the adhesiveness of the pesticide particles to plant leaf surfaces are improved; double-coating gradual slow release is achieved, pesticide residues are gradually degraded, the effective action time of pesticides is prolonged, and pesticide residue pollution is reduced. # imgabs0 #

Description

Technical Field

[0001] The present invention relates to the technical field of insecticides, in particular to a high-efficiency insecticidal active material containing an indoxacarb molecular structure and a preparation method thereof. Background Art

[0002] Indoxacarb, a sodium channel inhibitor insecticide, holds a prominent position in global pest control thanks to its high efficacy, low toxicity, and unique mechanism of action. However, with long-term and extensive use, some pests have developed resistance to it, and its efficacy and stability under various environmental conditions are limited. To overcome these issues, researchers have modified and engineered the indoxacarb molecular structure to develop a series of derivatives designed to enhance its overall performance and meet the needs of modern agricultural green pest control.

[0003] Early research on indoxacarb focused on its active metabolite, DCJW (N-2-demethoxycarbonyl metabolite). It was discovered that by varying the substituents and functional group linkages within the DCJW molecule, its binding to sodium channels could be influenced. Based on this, researchers gradually developed derivatives with diverse properties by altering benzene ring substituents, adjusting heterocyclic structures, and modifying ester groups. Advances in organic synthesis techniques, such as transition metal-catalyzed reactions and the application of green synthesis methods, have significantly improved the efficiency and diversity of derivative synthesis, accelerating the development of new derivatives.

[0004] Numerous indoxacarb derivatives demonstrate excellent broad-spectrum insecticide activity, with highly effective lethality against a wide range of Lepidoptera, Coleoptera, and Hemiptera pests. Some derivatives are significantly more effective than the original indoxacarb against resistant pests such as the diamondback moth and cotton bollworm. In field trials, one new derivative achieved over 95% control of the diamondback moth, with a duration of effect lasting up to 15 days.

[0005] Some derivatives demonstrate excellent cross-resistance circumvention capabilities against pest populations already resistant to indoxacarb. Their unique molecular structure enables them to act in different ways on sodium ion channels, disrupting the pest's existing resistance mechanisms. For example, in experiments against resistant cotton bollworms, specific derivatives demonstrated insecticidal activity 2-3 times that of indoxacarb, providing a new and effective means of managing pest resistance.

[0006] Compared to traditional pesticides, many indoxacarb derivatives degrade faster in the environment and are less toxic to non-target organisms. Studies have shown that some derivatives have a half-life in soil that is more than 50% shorter than that of indoxacarb and significantly reduce toxicity to beneficial organisms such as bees and silkworms, helping to maintain ecosystem balance.

[0007] Despite the numerous advantages offered by indoxacarb derivatives, they still face several challenges. The complex and costly synthesis of some derivatives limits their large-scale industrial production and widespread application. During long-term use, whether pests will develop resistance to these new derivatives, and how to scientifically and rationally monitor and prevent this resistance, are also pressing issues to be addressed. Furthermore, further in-depth research is needed on the environmental behavior and ecological risk assessment of these derivatives to ensure their safe and sustainable use. Summary of the Invention

[0008] The object of the present invention is to provide a highly effective insecticidal active material containing the molecular structure of indoxacarb to solve the problems raised in the above background technology.

[0009] To achieve the above object, the present invention provides the following technical solutions:

[0010] A highly effective insecticidal active material containing an indoxacarb molecular structure, comprising: an active compound containing an indoxacarb molecular structure, sulfonic acid-modified sodium alginate, sodium alginate, a metal-organic framework material as a carrier, and a photodegradation accelerator;

[0011] The active compound containing the indoxacarb molecular structure is formed by combining indoxacarb and salicylic acid or phthalic acid. The structure of the active compound containing the indoxacarb molecular structure is shown in Formula 1 or Formula 2:

[0012]

[0013] Furthermore, the metal-organic framework material is one or a combination of MIL-100(Fe) and MIL-101(Fe).

[0014] Furthermore, the photodegradation accelerator is a ZnO / TiO2 composite nanomaterial.

[0015] Furthermore, the mass ratio of the sulfonic acid modified sodium alginate to sodium alginate is 1:08-1.2, and the sulfonic acid modified sodium alginate is modified with sulfonic acid R-SO3H, where R is NH2CH2CH2.

[0016] The present invention also provides a method for preparing the above-mentioned high-efficiency insecticidal active material containing the indoxacarb molecular structure, comprising the following steps:

[0017] S01, mixing a photodegradation accelerator with a sodium alginate aqueous solution, and then adding a mixed solution of ethanol and water containing 2% sodium chloride to react to obtain a coated photodegradation accelerator;

[0018] S02, placing the active compound containing the molecular structure of indoxacarb and the metal-organic framework material in ethanol, and ultrasonically dispersing them to obtain a drug-loaded metal-organic framework material;

[0019] S03. Mix the drug-loaded metal-organic framework material prepared in step S02, the coated photodegradation accelerator prepared in step S01, and an aqueous solution of sulfonic acid-modified sodium alginate, then add a mixed solution of ethanol and water containing 2% sodium chloride, and react to obtain a highly efficient insecticidal active material containing the molecular structure of indoxacarb.

[0020] Furthermore, in step S01, the mass concentration of the sodium alginate aqueous solution is 5-10%, and the mass volume ratio of the photodegradation accelerator to the sodium alginate aqueous solution is 0.8-5 g / L.

[0021] Furthermore, in step S02, the mass ratio of the active compound containing the indoxacarb molecular structure to the metal-organic framework material is 1:0.5-1.5, and the mass volume ratio of the active compound containing the indoxacarb molecular structure to ethanol is 0.01-0.1 g / mL.

[0022] Furthermore, in step S02, the preparation of the active compound containing the molecular structure of indoxacarb includes the following steps: adding indoxacarb to N,N-dimethylformamide, heating it to completely dissolve it, and then gradually adding salicylic acid or phthalic acid. After complete dissolution, the solvent is evaporated, and the obtained solid is washed with 95% ethanol. The product is the active compound containing the molecular structure of indoxacarb (indoxacarb salicylate or indoxacarb phthalate).

[0023] Furthermore, in step S03, the mass ratio of the drug-loaded metal-organic framework material prepared in step S02 to the coated photodegradation accelerator prepared in step S01 is 1:0.2-5, and the mass volume ratio of the drug-loaded metal-organic framework material prepared in step S02 to the sulfonic acid-modified sodium alginate aqueous solution is 0.1-5 g / L.

[0024] Furthermore, in step S03, the mass concentration of the sulfonic acid modified sodium alginate aqueous solution is 8-15%.

[0025] The present invention also provides an insecticide comprising the above-mentioned high-efficiency insecticidal active material containing the indoxacarb molecular structure.

[0026] Compared with the prior art, the present invention has the following beneficial effects:

[0027] The organic salt of indoxacarb salicylate or indoxacarb phthalate of the present invention can improve plant stress resistance and further enhance the insecticidal activity of indoxacarb. Compared with its precursor compound, the compound of the present invention exhibits significantly improved formulation processing properties, as well as wetting and penetration properties on plants, significantly enhancing its control efficacy against plant pests, particularly lepidopteran pests.

[0028] The present invention mixes a photodegradation accelerator with a sodium alginate aqueous solution and encapsulates the photodegradation accelerator inside. The present invention uses an iron-based metal organic framework material as a carrier, loads an active compound containing the molecular structure of indoxacarb, and then encapsulates the loaded compound and the encapsulated photodegradation accelerator in the sulfonic acid-modified sodium alginate, thereby improving the stability of the pesticide particles and the adhesion to the plant leaves.

[0029] The modified sodium alginate molecule contains a large number of sulfonic acid groups. Sulfonic acid groups are highly ionizable and hydrophilic. Their introduction into the sodium alginate molecule improves drug loading. The sulfonic acid groups on the surface adsorb drug molecules, significantly eliminating the burst release phenomenon caused by physical adsorption on the material's surface. The photodegradation accelerator is coated with sodium alginate, which has excellent interfacial affinity, facilitating the attachment of drug-loaded metal-organic frameworks, further increasing drug loading.

[0030] Under environmental influences, the outer layer of sulfonic acid-modified sodium alginate gradually decomposes, releasing the drug-loaded metal-organic framework (MOF) material, and thus the active compound containing the indoxacarb molecular structure. This active compound exhibits a strong pest control effect. Following the gradual decomposition of the outer layer, the inner sodium alginate also gradually decomposes, releasing the photodegradation accelerator. Sunlight exposure gradually degrades the pesticide residue, resulting in a double coating that slowly releases the pesticide, gradually degrading the residue, extending its effective duration and reducing pesticide residue pollution. DETAILED DESCRIPTION

[0031] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0032] The preparation of an active compound containing the indoxacarb molecular structure comprises the following steps: adding 0.5 mol of indoxacarb to 1 L of N,N-dimethylformamide, heating to completely dissolve it, gradually adding 0.5 mol of salicylic acid or phthalic acid, and after complete dissolution, distilling off the solvent, and washing the resulting solid with 100 ml of 95% ethanol. The product is the active compound containing the indoxacarb molecular structure (indoxacarb salicylate or indoxacarb phthalate).

[0033] The preparation of sulfonic acid-modified sodium alginate includes the following steps: 7g of sodium alginate is added to 300mL of phosphate buffer solution. After complete dissolution, 1-ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride is added. After mechanical stirring for 20 minutes, N-hydroxysuccinimide and sulfonic acid (NH₂CH₂CH₂-SO₃H) are added. The molar ratio of sodium alginate to 1-ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride and N-hydroxysuccinimide is 1:1:1. The reaction is carried out at 25°C for 24 hours. After completion of the reaction, precipitation is performed with 2-3 volumes of isopropanol, followed by redissolution with deionized water to a saturated solution. This cycle is repeated three times. The alginate is then dialyzed for 48 hours and freeze-dried to obtain the sulfonic acid-modified sodium alginate. This is prepared using the method of patent CN 105816920A.

[0034] ZnO / TiO2 composite nanomaterials, Xi'an Qiyue Biotechnology Co., Ltd.

[0035] Example 1

[0036] A method for preparing a highly effective insecticidal active material containing an indoxacarb molecular structure comprises the following steps:

[0037] S01, after mixing 5g of photodegradation accelerator with 1L of 5wt% sodium alginate aqueous solution for 10min, add 0.5-1L of a mixed solution of ethanol and water (volume ratio 7:3) containing 2% sodium chloride and continue stirring at 5°C for 30min, let it stand for 1h, and filter to obtain the coated photodegradation accelerator. The wet material is ready for use and can be dried if it is not used temporarily;

[0038] S02, placing 10 g of an active compound containing the molecular structure of indoxacarb (indoxacarb salicylate) and 10 g of MIL-100(Fe) in 500 mL of ethanol, ultrasonically dispersing them, filtering, and drying to obtain a drug-loaded metal-organic framework material;

[0039] S03. Mix 5 g of the drug-loaded metal-organic framework material prepared in step S02 and 2 g of the coated photodegradation accelerator prepared in step S01, add them to 1 L of a 10% sulfonic acid-modified sodium alginate aqueous solution, and then add 0.5-1 L of a mixed solution of ethanol containing 2% sodium chloride and water (volume ratio 7:3). Continue stirring at 5°C for 30 minutes, let it stand for 1 hour, filter, and dry to obtain a high-efficiency insecticidal active material containing the indoxacarb molecular structure.

[0040] Example 2

[0041] A method for preparing a highly effective insecticidal active material containing an indoxacarb molecular structure comprises the following steps:

[0042] S01, after mixing 5g of photodegradation accelerator with 1L of 5wt% sodium alginate aqueous solution for 10min, add 0.5-1L of a mixed solution of ethanol and water (volume ratio 7:3) containing 2% sodium chloride and continue stirring at 5°C for 30min, let it stand for 1h, and filter to obtain the coated photodegradation accelerator. The wet material is ready for use and can be dried if it is not used temporarily;

[0043] S02, placing 10 g of an active compound containing the molecular structure of indoxacarb (indoxacarb phthalate) and 10 g of MIL-100(Fe) in 500 mL of ethanol, ultrasonically dispersing them, filtering, and drying to obtain a drug-loaded metal-organic framework material;

[0044] S03. Mix 5 g of the drug-loaded metal-organic framework material prepared in step S02 and 2 g of the coated photodegradation accelerator prepared in step S01, add them to 1 L of a 10% sulfonic acid-modified sodium alginate aqueous solution, and then add 0.5-1 L of a mixed solution of ethanol containing 2% sodium chloride and water (volume ratio 7:3). Continue stirring at 5°C for 30 minutes, let it stand for 1 hour, filter, and dry to obtain a high-efficiency insecticidal active material containing the indoxacarb molecular structure.

[0045] Example 3

[0046] A method for preparing a highly effective insecticidal active material containing an indoxacarb molecular structure comprises the following steps:

[0047] S01, after mixing 5g of photodegradation accelerator with 1L of 5wt% sodium alginate aqueous solution for 10min, add 0.5-1L of a mixed solution of ethanol and water (volume ratio 7:3) containing 2% sodium chloride and continue stirring at 5°C for 30min, let it stand for 1h, and filter to obtain the coated photodegradation accelerator. The wet material is ready for use and can be dried if it is not used temporarily;

[0048] S02, placing 10 g of an active compound containing the molecular structure of indoxacarb (indoxacarb phthalate) and 10 g of MIL-100(Fe) in 500 mL of ethanol, ultrasonically dispersing them, filtering, and drying to obtain a drug-loaded metal-organic framework material;

[0049] S03. Mix 5 g of the drug-loaded metal-organic framework material prepared in step S02 and 2 g of the coated photodegradation accelerator prepared in step S01, add them to 1 L of a 15% sulfonic acid-modified sodium alginate aqueous solution, and then add 0.5-1 L of a mixed solution of ethanol containing 2% sodium chloride and water (volume ratio 7:3). Continue stirring at 5°C for 30 minutes, let it stand for 1 hour, filter, and dry to obtain a high-efficiency insecticidal active material containing the indoxacarb molecular structure.

[0050] Example 4

[0051] A method for preparing a highly effective insecticidal active material containing an indoxacarb molecular structure comprises the following steps:

[0052] S01, after mixing 5g of photodegradation accelerator with 1L of 5wt% sodium alginate aqueous solution for 10min, add 0.5-1L of a mixed solution of ethanol and water (volume ratio 7:3) containing 2% sodium chloride and continue stirring at 5°C for 30min, let it stand for 1h, and filter to obtain the coated photodegradation accelerator. The wet material is ready for use and can be dried if it is not used temporarily;

[0053] S02, placing 10 g of an active compound containing the molecular structure of indoxacarb (indoxacarb phthalate) and 10 g of MIL-100(Fe) in 500 mL of ethanol, ultrasonically dispersing them, filtering, and drying to obtain a drug-loaded metal-organic framework material;

[0054] S03. Mix 5 g of the drug-loaded metal-organic framework material prepared in step S02 and 2 g of the coated photodegradation accelerator prepared in step S01, add them to 1 L of an 8% sulfonic acid-modified sodium alginate aqueous solution, and then add 0.5-1 L of a mixed solution of ethanol containing 2% sodium chloride and water (volume ratio 7:3). Continue stirring at 5°C for 30 minutes, let it stand for 1 hour, filter, and dry to obtain a high-efficiency insecticidal active material containing the indoxacarb molecular structure.

[0055] Comparative Example 1

[0056] A method for preparing a highly effective insecticidal active material containing an indoxacarb molecular structure comprises the following steps:

[0057] S01, after mixing 5g of photodegradation accelerator with 1L of 5wt% sodium alginate aqueous solution for 10min, add 0.5-1L of a mixed solution of ethanol and water (volume ratio 7:3) containing 2% sodium chloride and continue stirring at 5°C for 30min, let it stand for 1h, and filter to obtain the coated photodegradation accelerator. The wet material is ready for use and can be dried if it is not used temporarily;

[0058] S02, placing 10 g of an active compound containing the molecular structure of indoxacarb (indoxacarb phthalate) and 10 g of MIL-100(Fe) in 500 mL of ethanol, ultrasonically dispersing them, filtering, and drying to obtain a drug-loaded metal-organic framework material;

[0059] S03. 5 g of the drug-loaded metal-organic framework material prepared in step S02 and 2 g of the coated photodegradation accelerator prepared in step S01 were mixed and added to 1 L of a 20% aqueous solution of sulfonic acid-modified sodium alginate. After mixing, 0.5-1 L of a mixed solution of ethanol containing 2% sodium chloride and water (volume ratio 7:3) was added. The mixture was stirred at 5°C for 30 minutes, allowed to stand for 1 hour, filtered, and dried to obtain a highly effective insecticidal material containing the indoxacarb molecular structure. Agglomeration was observed.

[0060] Comparative Example 2

[0061] A method for preparing a highly effective insecticidal active material containing an indoxacarb molecular structure comprises the following steps:

[0062] S01, after mixing 0.5g of photodegradation accelerator with 1L of 5wt% sodium alginate aqueous solution for 10min, add 0.5-1L of a mixed solution of ethanol and water (volume ratio 7:3) containing 2% sodium chloride at 5°C and continue stirring for 30min, let it stand for 1h, and filter to obtain the coated photodegradation accelerator. The wet material is ready for use. If it is not used temporarily, it can be dried;

[0063] S02, placing 10 g of an active compound containing the molecular structure of indoxacarb (indoxacarb phthalate) and 10 g of MIL-100(Fe) in 500 mL of ethanol, ultrasonically dispersing them, filtering, and drying to obtain a drug-loaded metal-organic framework material;

[0064] S03. Mix 5 g of the drug-loaded metal-organic framework material prepared in step S02 and 2 g of the coated photodegradation accelerator prepared in step S01, add them to 1 L of a 10% sulfonic acid-modified sodium alginate aqueous solution, and then add 0.5-1 L of a mixed solution of ethanol containing 2% sodium chloride and water (volume ratio 7:3). Continue stirring at 5°C for 30 minutes, let it stand for 1 hour, filter, and dry to obtain a high-efficiency insecticidal active material containing the indoxacarb molecular structure.

[0065] Comparative Example 3

[0066] A method for preparing a highly effective insecticidal active material containing an indoxacarb molecular structure comprises the following steps:

[0067] S01, after mixing 5g of photodegradation accelerator with 1L of 5wt% sodium alginate aqueous solution for 10min, add 0.5-1L of a mixed solution of ethanol and water (volume ratio 7:3) containing 2% sodium chloride and continue stirring at 5°C for 30min, let it stand for 1h, and filter to obtain the coated photodegradation accelerator. The wet material is ready for use and can be dried if it is not used temporarily;

[0068] S02, placing 10 g of an active compound containing the molecular structure of indoxacarb (indoxacarb phthalate) and 10 g of MIL-100(Fe) in 500 mL of ethanol, ultrasonically dispersing them, filtering, and drying to obtain a drug-loaded metal-organic framework material;

[0069] S03. Mix 5 g of the drug-loaded metal-organic framework material prepared in step S02 and 0.8 g of the coated photodegradation accelerator prepared in step S01, add them to 1 L of a 10% sulfonic acid-modified sodium alginate aqueous solution, and then add 0.5-1 L of a mixed solution of ethanol containing 2% sodium chloride and water (volume ratio 7:3). Continue stirring at 5°C for 30 minutes, let it stand for 1 hour, filter, and dry to obtain a high-efficiency insecticidal active material containing the indoxacarb molecular structure.

[0070] Performance Testing Methods: Field Efficacy Test: The test was conducted in accordance with the test methods in GB / T 17980.13-2000, "Guidelines for Field Efficacy Tests of Pesticides." Cabbage was used as the test crop, and the test agent was a highly effective insecticidal material containing the indoxacarb molecular structure, produced from the same batch as in Examples 1-3 and stored under the same conditions. The blank control agent used was water. The application rate was 10 g / mu, and the water consumption was 25 kg / mu.

[0071] Apply the pesticide once during the peak period of the 2nd to 3rd instar larvae of the diamondback moth. Record the number of live insects before, 3 days after, 7 days after, and 14 days after application to calculate the control efficacy. The survey and record method uses the five-point sampling method. The control efficacy calculation formula is as follows:

[0072] Control effect (%) = (1-(number of live insects in the blank area before treatment × number of live insects in the treated area after treatment) / (number of live insects in the blank area after treatment × number of live insects in the treated area before treatment)) × 100.

[0073] Table 1 Control effect data

[0074]

[0075] Detection of residual amount of active compounds containing the molecular structure of indoxacarb: Cabbage samples were collected before application, 3 days after application, 7 days after application, and 14 days after application using a five-point sampling method, and the residual amount of active compounds containing the molecular structure of indoxacarb in the cabbage samples was determined by high performance liquid chromatography-mass spectrometry.

[0076] Table 2 Residue detection data

[0077]

[0078]

[0079] Tables 1 and 2 show that the highly effective insecticidal active material containing the indoxacarb molecular structure of the present application has good control effects and low pesticide residues. The sulfonic acid-modified alginic acid and sodium alginate of the present application gradually decompose and slowly release the active compound containing the indoxacarb molecular structure and the ZnO / TiO2 composite nanomaterial.

[0080] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus.

[0081] It should be noted that the above content merely illustrates the technical idea of ​​the present invention and cannot be used to limit the scope of protection of the present invention. For ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications all fall within the scope of protection of the claims of the present invention.

Claims

1. A highly effective insecticidal active material containing the molecular structure of indoxacarb, characterized in that: Contains: active compound with indoxacarb molecular structure, sulfonic acid modified sodium alginate, sodium alginate, metal-organic framework material as carrier, photodegradation accelerator; The active compound containing the indoxacarb molecular structure is formed by combining indoxacarb and salicylic acid or phthalic acid. The structure of the active compound containing the indoxacarb molecular structure is shown in Formula 1 or Formula 2:

2. The highly effective insecticidal active material containing the indoxacarb molecular structure according to claim 1, characterized in that: The metal-organic framework material is one of MIL-100(Fe) and MIL-101(Fe) or a combination of the two.

3. The highly effective insecticidal active material containing the indoxacarb molecular structure according to claim 1, characterized in that: The photodegradation accelerator is a ZnO / TiO2 composite nanomaterial.

4. The highly effective insecticidal active material containing the indoxacarb molecular structure according to claim 1, characterized in that: The mass ratio of the sulfonic acid modified sodium alginate to sodium alginate is 1:08-1.

2. The sulfonic acid modified sodium alginate is modified with sulfonic acid R-SO3H, where R is NH2CH2CH2.

5. A method for preparing a highly effective insecticidal active material containing an indoxacarb molecular structure according to any one of claims 1 to 4, characterized in that: The following steps are involved: S01, mixing a photodegradation accelerator with a sodium alginate aqueous solution, and then adding a mixed solution of ethanol and water containing 2% sodium chloride to react to obtain a coated photodegradation accelerator; S02, placing the active compound containing the molecular structure of indoxacarb and the metal-organic framework material in ethanol, and ultrasonically dispersing them to obtain a drug-loaded metal-organic framework material; S03. Mix the drug-loaded metal-organic framework material prepared in step S02, the coated photodegradation accelerator prepared in step S01, and an aqueous solution of sulfonic acid-modified sodium alginate, then add a mixed solution of ethanol and water containing 2% sodium chloride, and react to obtain a highly efficient insecticidal active material containing the molecular structure of indoxacarb.

6. The method for preparing a highly effective insecticidal active material containing the indoxacarb molecular structure according to claim 5, characterized in that: The mass concentration of the sodium alginate aqueous solution in step S01 is 5-10%, and the mass volume ratio of the photodegradation accelerator to the sodium alginate aqueous solution is 0.8-5 g / L.

7. The method for preparing a highly effective insecticidal active material containing an indoxacarb molecular structure according to claim 5, characterized in that: In step S02, the mass ratio of the active compound containing the indoxacarb molecular structure to the metal-organic framework material is 1:0.5-1.5, and the mass volume ratio of the active compound containing the indoxacarb molecular structure to ethanol is 0.01-0.1 g / mL.

8. The method for preparing a highly effective insecticidal active material containing an indoxacarb molecular structure according to claim 5, characterized in that: In step S02, the preparation of the active compound containing the indoxacarb molecular structure includes the following steps: Indoxacarb is added to N,N-dimethylformamide, heated to completely dissolve it, and then salicylic acid or phthalic acid is gradually added. After complete dissolution, the solvent is evaporated and the resulting solid is washed with 95% ethanol. The product is an active compound containing the indoxacarb molecular structure.

9. The method for preparing a highly effective insecticidal active material containing an indoxacarb molecular structure according to claim 5, characterized in that: In step S03, the mass ratio of the drug-loaded metal-organic framework material prepared in step S02 and the coated photodegradation accelerator prepared in step S01 is 1:0.2-5, the mass volume ratio of the drug-loaded metal-organic framework material prepared in step S02 and the sulfonic acid-modified sodium alginate aqueous solution is 0.1-5 g / L, and the concentration of the sulfonic acid-modified sodium alginate aqueous solution is 8-15%.

10. An insecticide, characterized in that The invention relates to a highly effective insecticidal active material comprising the indoxacarb molecular structure as claimed in any one of claims 1 to 4.

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