Preparation process of mulberry, melon, fruit and vegetable protein paste capable of repairing islet cells and promoting insulin secretion

Abstract

The invention provides a preparation process of mulberry, melon, fruit and vegetable protein paste for repairing islet cells and promoting insulin secretion, and relates to the technical field of hypoglycemic products. The prescription comprises a mulberry leaf extract, a bitter gourd extract, a white gourd extract, a cyclocarya paliurus extract, a sweet ampelopsis grossedentata extract, cucumbers, pumpkins, onions, corn stigma, lettuces, brassica juncea, asparagus, Chinese yams, radix puerariae, purple cabbages, broccoli, carrots, hericium erinaceus, black beans, white beans, zebra beans, hyacinth beans, cordyceps flowers, mushrooms, needle mushrooms, undaria pinnatifida, spirulina, leek seeds, lotus seeds, almonds, quinoa and spina date seeds. , chia seeds, pumpkin seeds, silkworm chrysalis and tenebrio molitor. The traditional Chinese medicine composition is prepared according to the traditional Chinese medicine theory and a scientific formula, and clinical verification shows that the traditional Chinese medicine composition has the effects of reducing blood sugar and blood fat, promoting digestion, invigorating the stomach, nourishing the liver and tonifying the kidney, can effectively improve and prevent diabetes mellitus, can also regulate gastrointestinal peristalsis and is helpful for regulating constipation. The prescription is simple to operate, low in cost and suitable for mass production.

Description

Technical Field

[0001] The present invention relates to the technical field of hypoglycemic products, and in particular to a process for preparing a mulberry, melon, fruit and vegetable protein paste for repairing pancreatic islet cells and promoting insulin secretion. Background Art

[0002] The global incidence of diabetes is rapidly increasing due to factors such as rising living standards, changing diets, increasingly hectic lifestyles, and sedentary lifestyles. According to statistics, diabetes has become the third most serious chronic disease threatening human health, after cancer and cardiovascular and cerebrovascular diseases. Diabetes is a progressive, systemic disease caused by uncontrolled blood sugar levels. It is associated with numerous and serious complications. Clinical treatment, in addition to insulin injections, primarily involves oral hypoglycemic medications such as sulfonylureas and biguanides, which carry certain side effects. There is a need for foods with hypoglycemic properties to replace these medications and avoid the side effects of Western medications. To fundamentally address diabetes, we must address digestion, absorption, and detoxification. The production process of mulberry and melon fruit and vegetable protein paste is designed to aid gastrointestinal digestion, absorption, and detoxification. Furthermore, the development of mulberry and melon functional foods encompasses multiple aspects, from raw material selection, extraction and isolation of functional factors, processing technology, to quality control. Furthermore, the support of relevant national laws and regulations safeguards the healthy development of functional foods. Summary of the Invention

[0003] The present invention aims to provide a process for preparing a mulberry, melon, and vegetable protein paste that has the effects of lowering blood sugar and lipids, promoting digestion and strengthening the stomach, nourishing the liver and kidneys, and strengthening the body. The hypoglycemic food repairs pancreatic islet beta cells and promotes their secretion of insulin. Insulin is an important hormone for regulating blood sugar. It promotes the uptake and utilization of glucose by muscle, adipose tissue, and liver cells, thereby lowering blood sugar levels. The mulberry, melon, and vegetable protein paste can also regulate gastrointestinal motility, aid gastrointestinal detoxification, and has a significant improvement effect on people suffering from constipation.

[0004] The preparation process of the mulberry, melon, fruit and vegetable protein paste of the present invention is composed of the following raw materials in percentage by weight: 0.1-3 parts of mulberry leaf extract, 0.1-2 parts of bitter melon extract, 0.1-2 parts of wax gourd extract, 0.1-3 parts of green willow extract, 0.1-5 parts of sweet vine tea extract, 3-4 parts of cucumber, 2-5 parts of pumpkin, 1-3 parts of onion, 1-3 parts of corn silk, 1-2 parts of lettuce, 1-2 parts of spinach, 1-2 parts of asparagus, 1-3 parts of yam, 1-2 parts of kudzu root, 1-3 parts of purple cabbage, 1-4 parts of broccoli, 1- 3 portions, 2-4 portions of Hericium erinaceus, 2-5 portions of black beans, 1-3 portions of white cloud beans, 2-4 portions of zebra beans, 1-3 portions of lentils, 3-6 portions of cordyceps flowers, 2-5 portions of shiitake mushrooms, 2-4 portions of enoki mushrooms, 2-5 portions of kelp, 2-3 portions of spirulina, 2-4 portions of chive seeds, 1-3 portions of lotus seeds, 1-4 portions of almonds, 1-3 portions of quinoa, 2-5 portions of jujube kernels, 1-4 portions of chia seeds, 1-3 portions of pumpkin seeds, 5-7 portions of silkworm pupae, and 6-8 portions of mealworms.

[0005] The preparation process of the mulberry, melon, fruit and vegetable protein paste of the present invention comprises the following steps: (1) Wash a certain amount of fresh mulberry leaves, dry and crush them, add 5-10 times the volume of 65%-85% ethanol, ultrasonically extract for 2-3h, filter and concentrate the mulberry leaf extract at 45-55℃ in a vacuum to obtain mulberry leaf extract, dry the mulberry leaf extract at 50-60℃ for 20-35min, crush the dried material and pass it through a 100-mesh sieve for later use; (2) Slice a certain amount of fresh bitter melon and wax gourd whole fruit, dry and crush, add bitter melon powder and purified water in a ratio of 1:5, and then place in an extraction tank for low-temperature water extraction to obtain an extract, filter the extract under reduced pressure to obtain a filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.10 to 1.15 to obtain a bitter melon extract, dry the extract in an oven at 60 to 70°C, crush the dried product and pass it through a 100-mesh sieve for later use; (3) Mix a certain amount of Cyclocarya paliurus powder with a citric acid buffer solution of pH 4.5, add 0.8% cellulase, and perform enzymatic hydrolysis at 45°C for 20 minutes. After enzymatic hydrolysis, continue extraction at 80°C for 70 minutes, recover the extract, and vacuum concentrate the extract to an extract with a relative density of 1.10. Dry the extract in an oven at 60-70°C, crush the dried product, and pass it through a 100-mesh sieve for later use; (4) Add a certain amount of sweet vine tea raw material to water at a ratio of 1:25, adjust the pH value to 2.5, and add a small amount of L-cysteine ​​as a protective agent to prevent oxidation and degradation of the active ingredients during the extraction process. Heat the mixture to 90-95°C and extract for 50-60 minutes. Filter the mixture to obtain a preliminary extract, add a flocculant such as polyacrylamide to the filtrate, let it stand for 40-50 minutes to obtain a clear water extract, heat the clear water extract to boiling, then vacuum concentrate, and cool to 2-4°C to allow the extract to crystallize. After crystallization, rinse with deionized water, centrifuge and dehydrate, and finally microwave dry to obtain an off-white sweet vine tea extract; (5) A special method for preparing mealworms is to mix soybean residue and sweet vine tea powder in a ratio of 15:1, and let the mealworms feed on the mixture to grow. The grown and fat mealworms are dried and the powder is set aside; (6) Mix the various raw food materials to be used in proportion, grind them and stir them evenly, then sterilize them with ozone for 80-120 minutes to obtain a composition, and then pack them into small bags in a certain quantity.

[0006] Functions of various foods in the preparation process of the mulberry, melon, fruit and vegetable protein paste of the present invention:

[0007] Mulberry leaves are the leaves of the mulberry tree, a member of the Moraceae family. According to Traditional Chinese Medicine, mulberry leaves are bitter, sweet, and cold in nature, and have the effects of dispersing wind and heat, clearing the lungs and moistening dryness, clearing the liver and improving eyesight, lowering blood sugar, lipids, and blood pressure, providing antioxidant benefits, and enhancing immunity.

[0008] Bitter melon: It can stimulate insulin secretion, relieve stomach pain, anti-oxidation and anti-inflammatory, prevent and fight cancer, have antibacterial and antiviral effects, and enhance immunity.

[0009] Winter melon: It has diuretic, detoxifying and swelling-reducing effects, clears away heat and relieves summer heat, lowers blood pressure and blood sugar, moistens the lungs and relieves coughs, has anti-cancer and antioxidant effects, and can resolve phlegm and relieve coughs.

[0010] Cyclocarya paliurus: It has the effects of lowering blood sugar, lipids and blood pressure, anti-oxidation, anti-inflammatory, regulating immunity, protecting the liver and detoxifying, dispelling wind and relieving itching, reducing swelling and relieving pain.

[0011] Sweet vine tea is a blend of vine tea and sweet tea. The tea has a cool, sweet flavor and primarily contains flavonoids such as sweet tea. According to the Compendium of Materia Medica, flavonoids are recognized by the medical community as an excellent preventative for cardiovascular and cerebrovascular diseases, as well as for cancer prevention and treatment. They nourish the liver and kidneys, clear away heat and toxins, soothe sore throats, and reduce internal heat, while also moisturizing and removing freckles. Sweet tea extract has a significant preventative and therapeutic effect on obesity, hypertension, diabetes, and heart disease.

[0012] Cucumber: It has the effects of clearing heat and detoxifying, diuretic and reducing swelling, beautifying skin and anti-wrinkle, anti-cancer, lowering cholesterol and preventing arteriosclerosis, protecting the liver and lowering blood sugar.

[0013] Pumpkin: It has the effects of preventing and treating diabetes, lowering blood lipids, promoting gastrointestinal motility, preventing and fighting cancer, promoting the synthesis of melatonin and aiding sleep.

[0014] Onion: It can stimulate intestinal peristalsis, dilate blood vessels, promote insulin secretion, prevent cancer, enhance immunity, and prevent osteoporosis.

[0015] Corn silk: It has the effects of lowering blood sugar and blood pressure, diuresis and swelling, regulating nerves and resisting depression, antibacterial and anti-tumor, antioxidant and anti-aging.

[0016] Lettuce: It has the functions of promoting lactation, diuresis and defecation, clearing away heat and detoxifying, enhancing insulin sensitivity, regulating immunity, preventing and treating poverty and improving sleep, etc.

[0017] Spinach: It can promote digestion, prevent constipation, anti-inflammatory and antioxidant, enhance immunity, lower blood lipids and blood pressure, improve metabolism and control blood sugar, etc.

[0018] Asparagus: It has the effects of lowering blood pressure, blood lipids and blood sugar, anti-oxidation and anti-cancer, enhancing immunity, improving brain function, delaying neurological decline, and preventing osteoporosis.

[0019] Yam: It has the effects of strengthening the spleen, stomach and kidney, moistening the lungs and relieving cough, replenishing qi, nourishing yin and moistening dryness, delaying aging, enhancing immunity, lowering blood sugar and blood pressure.

[0020] Pueraria root: It has the effects of relieving muscles and reducing fever, promoting fluid production and quenching thirst, promoting the production of rashes, raising yang and stopping diarrhea, detoxifying and relieving alcohol, unblocking meridians, lowering blood pressure, lowering blood sugar and anti-inflammatory.

[0021] Purple cabbage: It promotes digestion, helps lower blood sugar, regulates blood lipids, prevents arteriosclerosis, lowers blood pressure and protects the heart, enhances immunity, and has antiviral effects.

[0022] Broccoli: It has the effects of enhancing immunity, anti-oxidation and anti-aging, preventing cancer, maintaining cardiovascular health, helping to lower blood pressure, and having antibacterial and anti-inflammatory effects.

[0023] Carrots: They have the functions of strengthening the spleen and removing stagnation, nourishing the liver and improving eyesight, clearing away heat and detoxifying, anti-oxidation and enhancing immunity, regulating blood pressure, and assisting in lowering blood sugar.

[0024] Hericium erinaceus: It has the functions of nourishing the liver and kidneys, strengthening the spleen and stomach, promoting digestion, lowering blood lipids and cholesterol, preventing and fighting cancer, and enhancing immunity.

[0025] Black beans: Known as the king of beans, they have the effects of nourishing the kidneys and blood, promoting blood circulation and removing blood stasis, anti-oxidation and anti-tumor, lowering cholesterol, and preventing arteriosclerosis.

[0026] White cloud beans: promote digestion, enhance immunity, strengthen the spleen and stomach, promote diuresis and reduce swelling, stop bleeding and relieve blood stasis, and regulate blood sugar and blood lipids.

[0027] Zebra beans: have the effects of enhancing immunity, replenishing blood and qi, regulating blood sugar and blood lipids, strengthening the spleen and removing dampness, nourishing yin and strengthening yang, and promoting digestion.

[0028] Lentils: They have the effects of strengthening the spleen and eliminating dampness, harmonizing the middle and relieving heat, treating leucorrhea, detoxifying, clearing away heat and dampness, replenishing qi and benefiting blood.

[0029] Cordyceps flower: It has obvious effects of enhancing immunity, promoting antibody production, anti-inflammatory and anti-oxidative aging, and assisting in the treatment of respiratory system.

[0030] Shiitake mushrooms: They have the effects of enhancing immunity, inhibiting the growth of cancer cells, lowering blood pressure and blood lipids, lowering cholesterol, and promoting insulin secretion.

[0031] Enoki mushrooms: They have the functions of nourishing the liver and kidneys, strengthening the spleen and stomach, promoting digestion, lowering blood lipids and cholesterol, preventing and fighting cancer, and enhancing immunity.

[0032] Kelp: It has anti-inflammatory, immunity-enhancing, anti-cancer and antiviral effects, promotes intestinal motility, lowers blood pressure and prevents arteriosclerosis.

[0033] Spirulina: It has the effects of enhancing immunity, improving cardiovascular health, anti-aging and antioxidant, protecting eyesight, improving metabolism and lowering blood sugar.

[0034] Leek seeds: have the effects of nourishing the kidney and strengthening yang, consolidating essence and reducing urine, stopping bleeding and improving eyesight, promoting lactation, anti-oxidation, lowering cholesterol, and softening cardiovascular system.

[0035] Lotus seeds: They have the effects of nourishing the spleen and stopping diarrhea, benefiting the kidneys and clearing the body to stop leukorrhea, replenishing qi, nourishing the heart and calming the mind, clearing away heat and detoxifying, lowering blood pressure and enhancing immunity.

[0036] Almonds: They have the effects of lowering cholesterol, protecting the heart, controlling blood sugar and blood pressure, relieving cough and asthma, detoxifying and reducing swelling, and enhancing immunity.

[0037] Quinoa: It has the effects of lowering cholesterol, preventing arteriosclerosis, anti-oxidation and anti-inflammatory, enhancing immunity and disease resistance.

[0038] Chinese jujube seeds: have the effects of nourishing the heart and calming the mind, calming and inducing sleep, improving memory, reducing sweat and promoting body fluid, relieving restlessness and thirst, and protecting the cardiovascular system.

[0039] Chia seeds: promote intestinal motility, improve intestinal flora, cleanse the intestines and detoxify, lower postprandial blood sugar levels, prevent arteriosclerosis, etc.

[0040] Pumpkin seeds: They have the effects of protecting the heart, anti-oxidation and anti-aging, regulating blood sugar and blood lipids, relieving stress and helping sleep, diuresis, and anti-cancer.

[0041] Silkworm pupae: They have the effects of inhibiting tumor proliferation, lowering blood sugar and blood lipids, protecting the liver, resisting fatigue, and significantly enhancing immunity.

[0042] Mealworms: have anti-cancer, immunity-enhancing, blood pressure and blood lipid lowering, antioxidant, blood lipid lowering, blood sugar regulation, and anti-aging effects.

[0043] The raw materials used in the production process of the mulberry fruit and vegetable protein paste of the present invention are all "Chinese medicinal materials that can be used for health food" and "Chinese medicinal materials that are both food and medicine" approved by the Ministry of Health, and are all collected from authentic places of origin. This functional food is made according to traditional Chinese medical theory through strict selection and fine processing according to a scientific formula. It integrates naturalness, nutrition, and deliciousness, and can provide a variety of health-care nutrients required by the human body. It has been clinically verified that long-term consumption can play the role of lowering blood sugar and lipids, promoting digestion and strengthening the stomach, nourishing the liver and kidneys, and strengthening the body. It is a hypoglycemic functional food with the effects of eliminating fatigue, delaying aging, and enhancing the body's immunity. In the present invention, the raw materials are dried, crushed, mixed, and sterilized to obtain a hypoglycemic composition. The production process is simple, low in cost, and suitable for mass production. At the same time, the production method will not damage the active ingredients of the raw materials, and can allow the active ingredients to better play a role, thereby significantly improving the blood sugar level in the body. BRIEF DESCRIPTION OF THE DRAWINGS

[0044] A process flow chart for producing a mulberry, melon, and vegetable protein paste for repairing pancreatic islet cells and promoting insulin secretion. This chart lists 36 functional foods needed in order of chronological order around a large circle, and indicates the required dosage range for each functional food. Simply crush and mix these 36 functional foods as required, then package them into small bags in a predetermined amount.

[0045] Specific implementation method.

[0046] Example 1 A preparation process of a mulberry, melon, fruit and vegetable protein paste for repairing pancreatic islet cells and promoting insulin secretion comprises the following raw materials in percentage by weight: 1 part mulberry leaf extract, 1 part bitter melon extract, 1 part wax gourd extract, 2 parts green onion extract, 3 parts sweet vine tea extract, 4 parts cucumber, 4.5 parts pumpkin, 2.5 parts onion, 3 parts corn silk, 2 parts lettuce, 2 parts spinach, 2 parts asparagus, 2.2 parts yam, 2 parts kudzu root, 2.3 parts purple cabbage, 2.9 parts broccoli, 2.8 parts carrot, 3.3 parts hericium erinaceus, 3.8 parts black bean, 2.9 parts white cloud bean, 3.4 parts zebra bean, 1.8 parts lentil, 4.5 parts cordyceps flower, 3.6 parts shiitake mushroom, 3.2 parts enoki mushroom, 3.2 parts wakame, 2.8 parts spirulina, 2.5 parts chive seeds, 1.2 parts lotus seeds, 1.3 parts almonds, 1.5 parts quinoa, 2.8 parts jujube kernel, 1.9 parts chia seeds, 2.7 parts pumpkin seeds, 5.7 parts silkworm pupae, 7.7 parts mealworms.

[0047] The production method is: (1) Wash a certain amount of fresh mulberry leaves, dry and crush them, add 5-10 times the volume of 65%-85% ethanol, ultrasonically extract for 2-3h, filter and concentrate the mulberry leaf extract at 45-55℃ in a vacuum to obtain mulberry leaf extract, dry the mulberry leaf extract at 50-60℃ for 20-35min, crush the dried material and pass it through a 100-mesh sieve for later use; (2) Slice a certain amount of fresh bitter melon and wax gourd whole fruit, dry and crush, add bitter melon powder and purified water in a ratio of 1:5, and then place in an extraction tank for low-temperature water extraction to obtain an extract, filter the extract under reduced pressure to obtain a filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.10 to 1.15 to obtain a bitter melon extract, dry the extract in an oven at 60 to 70°C, crush the dried product and pass it through a 100-mesh sieve for later use; (3) Mix a certain amount of Cyclocarya paliurus powder with a citric acid buffer solution of pH 4.5, add 0.8% cellulase, and perform enzymatic hydrolysis at 45°C for 20 minutes. After enzymatic hydrolysis, continue extraction at 80°C for 70 minutes, recover the extract, and vacuum concentrate the extract to an extract with a relative density of 1.10. Dry the extract in an oven at 60-70°C, crush the dried product, and pass it through a 100-mesh sieve for later use; (4) Add a certain amount of sweet vine tea raw material to water at a ratio of 1:25, adjust the pH value to 2.5, and add a small amount of L-cysteine ​​as a protective agent to prevent oxidation and degradation of the active ingredients during the extraction process. Heat the mixture to 90-95°C and extract for 50-60 minutes. Filter the mixture to obtain a preliminary extract, add a flocculant such as polyacrylamide to the filtrate, let it stand for 40-50 minutes to obtain a clear water extract, heat the clear water extract to boiling, then vacuum concentrate, and cool to 2-4°C to allow the extract to crystallize. After crystallization, rinse with deionized water, centrifuge and dehydrate, and finally microwave dry to obtain an off-white sweet vine tea extract; (5) A special method for preparing mealworms is to mix soybean residue and sweet vine tea powder in a ratio of 15:1, and let the mealworms feed on the mixture to grow. The grown and fat mealworms are dried and the powder is set aside; (6) Mix the various raw food materials to be used in proportion, grind them and stir them evenly, then sterilize them with ozone for 80-120 minutes to obtain a composition, and then pack them into small bags in a certain quantity.

[0048] Example 2 A preparation process of a mulberry, melon, fruit and vegetable protein paste for repairing pancreatic islet cells and promoting insulin secretion comprises the following raw materials in percentage by weight: 0.9 parts of mulberry leaf extract, 0.8 parts of bitter melon extract, 0.8 parts of wax gourd extract, 1.8 parts of green onion extract, 2.8 parts of sweet vine tea extract, 4 parts of cucumber, 4.5 parts of pumpkin, 3 parts of onion, 3 parts of corn silk, 2 parts of lettuce, 2 parts of spinach, 1.8 parts of asparagus, 2.5 parts of yam, 2 parts of kudzu root, 3 parts of purple cabbage, 3.5 parts of broccoli, 3 parts of carrot, 3.8 parts of hericium erinaceus, 4% of black beans, 2.7 parts of white cloud beans, 3.5 parts of zebra beans, 2.5 parts of lentils, 5 parts of cordyceps flowers, 3 parts of shiitake mushrooms, 3 parts of enoki mushrooms, 2.2 parts of kelp, 2.5 parts of spirulina, 3 parts of chive seeds, 1.5 parts of lotus seeds, 1.5 parts of almonds, 1.8 parts of quinoa, 2 parts of jujube kernels, 1.2 parts of chia seeds, 2.2 parts of pumpkin seeds, 5.7 parts of silkworm pupae, and 7.5 parts of mealworms.

[0049] The preparation method is the same as that of Example 1.

[0050] Example 3 The preparation process of a mulberry fruit and vegetable protein paste for repairing pancreatic islet cells and promoting insulin secretion is composed of the following raw materials in percentage by weight: 1.1 parts of mulberry leaf extract, 0.9 parts of bitter melon extract, 0.9 parts of wax gourd extract, 2.2 parts of cyclocarya paliurus extract, 3.2 parts of sweet vine tea extract, 3.8 parts of cucumber, 4.7 parts of pumpkin, 2.6 parts of onion, 3 parts of corn silk, 2 parts of lettuce, 1.9 parts of spinach, 1.9 parts of asparagus, 2.8 parts of yam, 1.9 parts of kudzu root, 1.9 parts of purple mulberry leaf extract, 2.8 parts of citronella root, 1.9 parts of celery root, 2.8 parts of yam, 1.9 parts of kudzu root, 2.8 parts of celery ... 1.3 parts of cabbage, 1.4 parts of broccoli, 1.3 parts of carrots, 2.3 parts of hericium erinaceus, 3 parts of black beans, 3 parts of white cloud beans, 2.5 parts of zebra beans, 1.8 parts of lentils, 5.5 parts of cordyceps flowers, 3.9 parts of shiitake mushrooms, 4 parts of enoki mushrooms, 2.5 parts of kelp, 2.1 parts of spirulina, 3 parts of chive seeds, 1.8 parts of lotus seeds, 2 parts of almonds, 2.2 parts of quinoa, 3.8 parts of jujube kernels, 3.5 parts of chia seeds, 3 parts of pumpkin seeds, 6.4 parts of silkworm pupae, and 7.8 parts of mealworms.

[0051] The preparation method is the same as that of Example 1.

[0052] Example 4 The preparation process of a mulberry fruit and vegetable protein paste for repairing pancreatic islet cells and promoting insulin secretion is composed of the following raw materials in percentage by weight: 0.3 parts of mulberry leaf extract, 0.2 parts of bitter melon extract, 0.2 parts of wax gourd extract, 0.5 parts of Cyclocarya paliurus extract, 0.5 parts of sweet vine tea extract, 3.8 parts of cucumber, 4.7 parts of pumpkin, 2.6 parts of onion, 3 parts of corn silk, 2 parts of lettuce, 1.9 parts of spinach, 1.9 parts of asparagus, 2.8 parts of yam, 1.9 parts of kudzu root, 1.9 parts of purple pine needles, 1.9 parts of ... 1.3 parts of cabbage, 1.4 parts of broccoli, 1.3 parts of carrots, 2.3 parts of hericium erinaceus, 3 parts of black beans, 3 parts of white cloud beans, 2.5 parts of zebra beans, 1.8 parts of lentils, 5.5 parts of cordyceps flowers, 3.9 parts of shiitake mushrooms, 4 parts of enoki mushrooms, 2.5 parts of kelp, 2.1 parts of spirulina, 3 parts of chive seeds, 1.8 parts of lotus seeds, 2 parts of almonds, 2.2 parts of quinoa, 3.8 parts of jujube kernels, 3.5 parts of chia seeds, 3 parts of pumpkin seeds, 6.4 parts of silkworm pupae, and 7.8 parts of mealworms.

[0053] The preparation method is the same as that of Example 1.

[0054] Example 5 The preparation process of a mulberry fruit and vegetable protein paste for repairing pancreatic islet cells and promoting insulin secretion is composed of the following raw materials in percentage by weight: 0.2 parts of mulberry leaf extract, 0.3 parts of bitter melon extract, 0.3 parts of wax gourd extract, 0.6 parts of cyclocarya paliurus extract, 0.7 parts of sweet vine tea extract, 3.8 parts of cucumber, 4.7 parts of pumpkin, 2.6 parts of onion, 3 parts of corn silk, 2 parts of lettuce, 1.9 parts of spinach, 1.9 parts of asparagus, 2.8 parts of yam, 1.9 parts of kudzu root, 1.9 parts of purple pine needles, 1.9 parts of ... 1.3 parts of cabbage, 1.4 parts of broccoli, 1.3 parts of carrots, 2.3 parts of hericium erinaceus, 3 parts of black beans, 3 parts of white cloud beans, 2.5 parts of zebra beans, 1.8 parts of lentils, 5.5 parts of cordyceps flowers, 3.9 parts of shiitake mushrooms, 4 parts of enoki mushrooms, 2.5 parts of kelp, 2.1 parts of spirulina, 3 parts of chive seeds, 1.8 parts of lotus seeds, 2 parts of almonds, 2.2 parts of quinoa, 3.8 parts of jujube kernels, 3.5 parts of chia seeds, 3 parts of pumpkin seeds, 6.4 parts of silkworm pupae, and 7.8 parts of mealworms.

[0055] The preparation method is the same as that of Example 1.

[0056] clinical trials 90 diabetic patients who met the inclusion criteria, aged 40-60 years old, with an average age of 50.45 years old, were randomly divided into 6 groups, of which the first 5 groups corresponded to taking the mulberry fruit and vegetable protein paste of Examples 1-5 of the present invention, and took it with 50°C-80°C boiled water in the morning and evening, with a dosage of 40g, for 6 consecutive months. The 6 groups served as blank control groups. After 6 months, the physical condition of the patients was tested. The clinical manifestations of diabetic patients were: high blood sugar, abnormal glycosylated hemoglobin, high cholesterol and serum triglycerides. The specific data detected before and after taking are as follows (the data in the table are the average values ​​of each group):

[0057] Table 1 Statistics of usage results

[0058] As shown in Table 1, the mulberry fruit and vegetable protein paste of the present invention can significantly reduce the patient's blood sugar level, reduce the cholesterol and serum triglyceride levels in the body, and can also restore the body's glycosylated hemoglobin to normal. Compared with Examples 4-5, Examples 1-3 have better blood sugar and cholesterol-lowering effects and effectively promote the patient's fat metabolism. In summary, the mulberry fruit and vegetable protein paste of the present invention can significantly improve the human body's blood sugar level, restore the body's glycosylated hemoglobin to normal, and reduce cholesterol and serum triglycerides.

[0059] In summary, a mulberry fruit and vegetable protein paste with the effects of reducing blood sugar and lipids, promoting digestion and strengthening the stomach, nourishing the liver and kidneys, and strengthening the body of the embodiment of the present invention, it is through the repair of pancreatic islet β cells and promotes their secretion of insulin. Insulin is an important hormone for regulating blood sugar. It reduces blood sugar levels by promoting the uptake and utilization of glucose by muscle, adipose tissue and liver cells. Mulberry fruit and vegetable protein paste can also regulate gastrointestinal motility, can help gastrointestinal detoxification, and has a relatively improved effect on people with constipation. It has little irritation to the gastrointestinal tract and will not cause liver damage. In this production process, the raw materials are dried, crushed, mixed and sterilized to obtain a hypoglycemic composition. The production process is simple, low cost, and suitable for mass production. At the same time, this production method will not damage the active ingredients of the raw materials, and can allow the active ingredients to better play a role, thereby significantly improving blood sugar levels in the body.

[0060] The embodiments described above are some, but not all, of the embodiments of the present invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but rather merely represents selected embodiments of the present invention. All other embodiments derived by persons of ordinary skill in the art based on the embodiments of the present invention without inventive effort are also within the scope of protection of the present invention.

Claims

1. A process for preparing a mulberry, melon, fruit and vegetable protein paste for repairing pancreatic islet cells and promoting insulin secretion, characterized by: The invention is composed of the following raw materials in percentage by weight: 0.1-3 parts of mulberry leaf extract, 0.1-2 parts of bitter melon extract, 0.1-2 parts of wax gourd extract, 0.1-3 parts of cyclocarya paliurus extract, 0.1-5 parts of sweet vine tea extract, 3-4 parts of cucumber, 2-5 parts of pumpkin, 1-3 parts of onion, 1-3 parts of corn silk, 1-2 parts of lettuce, 1-2 parts of spinach, 1-2 parts of asparagus, 1-3 parts of yam, 1-2 parts of kudzu root, 1-3 parts of purple cabbage, 1-2 parts of broccoli. 4 portions, 1-3 portions of carrots, 2-4 portions of hericium erinaceus, 2-5 portions of black beans, 1-3 portions of white cloud beans, 2-4 portions of zebra beans, 1-3 portions of lentils, 3-6 portions of cordyceps flowers, 2-5 portions of shiitake mushrooms, 2-4 portions of enoki mushrooms, 2-5 portions of kelp, 2-3 portions of spirulina, 2-4 portions of chive seeds, 1-3 portions of lotus seeds, 1-4 portions of almonds, 1-3 portions of quinoa, 2-5 portions of jujube kernels, 1-4 portions of chia seeds, 1-3 portions of pumpkin seeds, 5-7 portions of silkworm pupae, and 6-8 portions of mealworms.

2. The preparation process of the mulberry, melon, fruit and vegetable protein paste according to claim 1, wherein the preparation method is: (1) Wash a certain amount of fresh mulberry leaves, dry and crush them, add 5-10 times the volume of ethanol with a concentration of 65%-85%, and ultrasonically extract for 2-3 hours. After filtering, vacuum concentrate the mulberry leaf extract at 45-55°C to obtain mulberry leaf extract. Dry the mulberry leaf extract at 50-60°C for 20-35 minutes, crush the dried product, and pass it through a 100-mesh sieve for later use; (2) Slice a certain amount of fresh bitter melon and wax gourd, dry and crush them, add bitter melon powder and purified water in a ratio of 1:5, and then place them in an extraction tank for low-temperature water extraction to obtain an extract, filter the extract under reduced pressure to obtain a filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.10-1.15 to obtain a bitter melon extract concentrate, place the extract concentrate in an oven at 60-70°C and dry it, crush the dried product and pass it through a 100-mesh sieve for later use; (3) Mix a certain amount of Cyclocarya paliurus powder with a citric acid buffer solution of pH 4.5, add 0.8% cellulase, and perform enzymatic hydrolysis at 45°C for 20 minutes. After enzymatic hydrolysis, continue to extract at 80°C for 70 minutes, recover the extract, and vacuum concentrate the extract to an extract with a relative density of 1.

10. Dry the extract in an oven at 60-70°C, crush the dried product, and pass it through a 100-mesh sieve for later use; (4) Add a certain amount of sweet vine tea raw material to water at a ratio of 1:25, adjust the pH value to 2.5, and add a small amount of L-cysteine ​​as a protective agent to prevent oxidation and degradation of the active ingredients during the extraction process. Heat the mixture to 90-95°C and extract for 50-60 minutes. Filter the mixture to obtain a preliminary extract, add a flocculant such as polyacrylamide to the filtrate, let it stand for 40-50 minutes to obtain a clear water extract, heat the clear water extract to boiling, then vacuum concentrate, cool to 2-4°C, and allow the extract to crystallize. After crystallization, rinse with deionized water, centrifuge for dehydration, and finally microwave dry to obtain an off-white sweet vine tea extract; (5) A special method for preparing mealworms is to mix soybean dregs and sweet vine tea powder in a ratio of 15:1, and let the mealworms feed on the mixture to grow. The grown and plump mealworms are dried and the powder is used for later use. (6) Mix the various raw food materials to be used in proportion, grind them and stir them evenly, then sterilize them with ozone for 80-120 minutes to obtain a composition, and then pack them into small bags in a certain quantity.

3. The preparation process of the mulberry, melon, fruit and vegetable protein paste according to claim 1, wherein: The invention is composed of the following raw materials in percentage by weight: 1 part of mulberry leaf extract, 1 part of bitter melon extract, 1 part of wax gourd extract, 2 parts of cyclocarya paliurus extract, 3 parts of sweet vine tea extract, 4 parts of cucumber, 4.5 parts of pumpkin, 2.5 parts of onion, 3 parts of corn silk, 2 parts of lettuce, 2 parts of spinach, 2 parts of asparagus, 2.2 parts of yam, 2 parts of kudzu root, 2.3 parts of purple cabbage, 2.9 parts of broccoli, 2.8 parts of carrot, 3. 3 parts, 3.8 parts of black beans, 2.9 parts of white cloud beans, 3.4 parts of zebra beans, 1.8 parts of lentils, 4.5 parts of cordyceps flowers, 3.6 parts of shiitake mushrooms, 3.2 parts of enoki mushrooms, 3.2 parts of kelp, 2.8 parts of spirulina, 2.5 parts of chive seeds, 1.2 parts of lotus seeds, 1.3 parts of almonds, 1.5 parts of quinoa, 2.8 parts of jujube kernels, 1.9 parts of chia seeds, 2.7 parts of pumpkin seeds, 5.7 parts of silkworm pupae, and 7.7 parts of mealworms.

4. The preparation process of the mulberry, melon, fruit and vegetable protein paste according to claim 1, wherein: The invention is composed of the following raw materials in percentage by weight: 0.9 parts of mulberry leaf extract, 0.8 parts of bitter melon extract, 0.8 parts of wax gourd extract, 1.8 parts of cyclocarya paliurus extract, 2.8 parts of sweet vine tea extract, 4 parts of cucumber, 4.5 parts of pumpkin, 3 parts of onion, 3 parts of corn silk, 2 parts of lettuce, 2 parts of spinach, 1.8 parts of asparagus, 2.5 parts of yam, 2 parts of kudzu root, 3 parts of purple cabbage, 3.5 parts of broccoli, and carrot. 3 parts of radish, 3.8 parts of hericium erinaceus, 4% of black beans, 2.7 parts of white cloud beans, 3.5 parts of zebra beans, 2.5 parts of lentils, 5 parts of cordyceps flowers, 3 parts of shiitake mushrooms, 3 parts of enoki mushrooms, 2.2 parts of kelp, 2.5 parts of spirulina, 3 parts of chive seeds, 1.5 parts of lotus seeds, 1.5 parts of almonds, 1.8 parts of quinoa, 2 parts of jujube kernels, 1.2 parts of chia seeds, 2.2 parts of pumpkin seeds, 5.7 parts of silkworm pupae, and 7.5 parts of mealworms.

5. The preparation process of the mulberry, melon, fruit and vegetable protein paste according to claim 1, wherein: The invention is composed of the following raw materials in percentage by weight: 1.1 parts of mulberry leaf extract, 0.9 parts of bitter melon extract, 0.9 parts of wax gourd extract, 2.2 parts of cyclocarya paliurus extract, 3.2 parts of sweet vine tea extract, 3.8 parts of cucumber, 4.7 parts of pumpkin, 2.6 parts of onion, 3 parts of corn silk, 2 parts of lettuce, 1.9 parts of spinach, 1.9 parts of asparagus, 2.8 parts of yam, 1.9 parts of kudzu root, 1.3 parts of purple cabbage, 1.4 parts of broccoli. , 1.3 parts of carrots, 2.3 parts of hericium erinaceus, 3 parts of black beans, 3 parts of white cloud beans, 2.5 parts of zebra beans, 1.8 parts of lentils, 5.5 parts of cordyceps flowers, 3.9 parts of shiitake mushrooms, 4 parts of enoki mushrooms, 2.5 parts of kelp, 2.1 parts of spirulina, 3 parts of chive seeds, 1.8 parts of lotus seeds, 2 parts of almonds, 2.2 parts of quinoa, 3.8 parts of jujube kernels, 3.5 parts of chia seeds, 3 parts of pumpkin seeds, 6.4 parts of silkworm pupae, and 7.8 parts of mealworms.

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