Psicose special medical food component as well as preparation method and application thereof

Abstract

The invention discloses a psicose special medical food component as well as a preparation method and application thereof, and belongs to the technical field of special food. According to the psicose special medical food assembly disclosed by the invention, various natural plant components are carefully selected, probiotics, prebiotics and psicose have a synergistic effect, and the psicose special medical food assembly comprises citrus fiber powder, oolong tea polypeptide, a semen cassiae extract, coconut oil, plant lactobacillus, resistant dextrin, galactomannan and other components. Through the steps of drying treatment, mixing, ultrasonic treatment, high-speed shearing, low-temperature drying and the like, the uniformity, stability and bioavailability of the composition are ensured. The psicose special medical food component disclosed by the invention has the effects of promoting intestinal health, enhancing metabolism, inhibiting fat absorption, controlling body weight, reducing the conversion of heat into fat, regulating blood fat, reducing the possibility of obesity formation and improving the immunity of a human body, and has positive effects on weight loss and body weight management.

Description

Technical Field

[0001] The present invention relates to the technical field of special foods, and more particularly to a psicose special medical food component and a preparation method and application thereof. Background Art

[0002] As the pace of modern life accelerates, unhealthy eating habits and sedentary lifestyles are contributing to the growing problem of obesity. Obesity, defined by the World Health Organization (WHO) as abnormal or excessive fat accumulation, is listed as a major risk factor for chronic diseases such as diabetes, cardiovascular disease, and cancer. Its impact has spread from high-income countries to low- and middle-income nations, creating a "double burden" of both infectious and chronic diseases.

[0003] Obesity-related health problems not only directly affect human health but also lead to significant economic costs, including direct medical expenses and indirect productivity losses. Therefore, it is particularly important to develop special medical food products that can help obese patients manage their weight and improve their metabolic health.

[0004] Therefore, providing a special medical food component of allulose and its preparation method and application is an urgent problem that needs to be solved by those skilled in the art. Summary of the Invention

[0005] In view of this, the present invention provides a psicose special medical food component and a preparation method and application thereof.

[0006] In order to achieve the above object, the present invention adopts the following technical solutions:

[0007] A method for preparing a psicose special medical food component comprises the following steps:

[0008] (1) 2-4 parts of Taxusin microcapsule powder, 1-3 parts of hawthorn powder, 2-4 parts of citrus fiber powder, 2-4 parts of mulberry leaf concentrate powder, 3-5 parts of brown algae powder, 0.5-1 part of dried ginger powder, 4-8 parts of resistant dextrin, 5-10 parts of allulose, and 2-4 parts of lotus leaf and cassia seed extract are mixed in a blender to obtain a mixed powder;

[0009] (2) mixing the mixed powder obtained in step (1) with the oat fiber skin extract in a mass ratio of 2:5 and performing ultrasonic treatment; the ultrasonic treatment conditions are: 100-300 W power, 30 kHz frequency, and treatment for 5-10 minutes; and subjecting the ultrasonically treated mixture to high-speed shearing at 8000-12000 rpm for 5-10 minutes to form solution A;

[0010] (3) mixing galactomannan and K carrageenan in a mass ratio of 1:1 to obtain plant colloid;

[0011] (4) mixing 30-50 parts of coconut oil, 5-10 parts of oolong tea polypeptide, 1-2 parts of Tween 80 and 2-4 parts of calcium lactate, and homogenizing to form a composite oil emulsion;

[0012] (5) the nutritional powder contains 45-55 parts of probiotic powder, 20-25 parts of trehalose, and 25-40 parts of skim milk powder;

[0013] (6) mixing the plant colloid obtained in step (3) with solution A prepared in step (2) at a mass ratio of 0.5:100, stirring at 70-85° C. at a rate of 300-500 rpm, and sol-sol for 1 hour to obtain glue solution B;

[0014] (7) cooling to 60° C., adding the composite oil emulsion prepared in step (4) to the glue solution B, adjusting the pH to 5.5-6.5 with citric acid buffer, and shearing at 10,000-12,000 rpm for 5 minutes to obtain glue solution C; the mass ratio of the glue solution B to the composite oil emulsion is 50:1;

[0015] (8) Add the nutritional powder obtained in step (5) to the gelatin solution C, homogenize for 10 minutes, add it to the mold, and cool it to 5-10°C to form stable gel particles; the mass ratio of the gelatin solution C to the nutritional powder is 10:1.

[0016] Furthermore, the preparation method of the dihydrotestosterone microcapsule powder in step (1) is as follows: octenyl succinate starch ester: β-cyclodextrin: deionized water are mixed in a mass ratio of 22:8:70, stirred and dissolved in a 70°C water bath, and then cooled; the pH is adjusted to 6 with citric acid, and a colostrum is formed by shearing at 8000 rpm for 5 minutes; the colostrum and dihydrotestosterone are mixed in a mass ratio of 20:1, homogenized at a pressure of 30 MPa for 20 minutes, and then pumped into a spray dryer for spray drying at an inlet air temperature of 140°C and a feed rate of 15 rpm. The dried product is dihydrotestosterone microcapsule powder.

[0017] Furthermore, the preparation method of the lotus leaf and cassia seed extract in step (1) is as follows: lotus leaf powder and cassia seed are mixed in a mass ratio of 1:1.5, and steamed at 103°C for 8-15 minutes; 1-2 times the volume of 85% ethanol is added and ground with a pulper, filtered with a 300-350 mesh sieve to remove the residue, and the filtrate is spray-dried to obtain the lotus leaf and cassia seed extract.

[0018] Furthermore, the preparation method of the oat fiber skin extract in step (2) is as follows: the oat fiber skin is crushed, passed through a 60-mesh sieve, 0.1 mol / L sodium hydroxide solution is added at a mass ratio of 1:20, and the mixture is reacted at 0.2 MPa and 130°C for 60 minutes; after cooling to room temperature, the mixture is filtered, and the filtrate is adjusted to a pH of 5.5-6.0 with a 1% hydrochloric acid solution, 0.2‰ cellulase and 0.1‰ medium-temperature amylase are added, the mixture is reacted at 40°C for 20 minutes, and the mixture is boiled for 10 minutes to obtain the oat fiber skin extract; the enzyme activity of the cellulase is 100,000 U / g; the enzyme activity of the medium-temperature amylase is 100,000 U / mL.

[0019] Furthermore, the preparation method of the probiotic powder in step (5) is as follows: diluting skim milk powder with water to a milk protein content of 3.0-3.5%, sterilizing at 95-98°C for 5-10 minutes to obtain a skim milk powder liquid; adding the probiotic composition to the skim milk powder liquid at a mass ratio of 1:1000, fermenting at 28-30°C for 12-18 hours until the acidity reaches 160-170°T, and then homogenizing, quick freezing, and drying to obtain the probiotic powder;

[0020] The probiotic composition contains 15-20 parts of plant lactic acid bacteria, 28-35 parts of Lactobacillus paracasei, 28-35 parts of Bifidobacterium breve, and 15-20 parts of Lactobacillus bulgaricus; the bacterial concentrations of the plant lactic acid bacteria, Lactobacillus paracasei, Bifidobacterium breve, and Lactobacillus bulgaricus are all 1.2 trillion CFU / g.

[0021] Furthermore, the method for preparing a psicose special medical food component is provided to obtain a psicose special medical food component.

[0022] Furthermore, the application of the allulose special medical food component in the preparation of weight loss products.

[0023] As can be seen from the above technical solutions, compared with the prior art, the present invention discloses a psicose special medical food component and its preparation method and application, which has the following beneficial effects:

[0024] (1) The nutritional properties of plant raw materials are superior, and no chemical substances are added. The product is naturally nutritious and has no side effects when consumed for a long time. The components can maintain the activity of the effective ingredients to the greatest extent through reasonable combination and processing.

[0025] (2) The product raw materials are added with prebiotic resistant dextrin, galactomannan and low-calorie, low-glycemic index D-psicose, which improve the taste while accelerating fat metabolism and improving insulin sensitivity, regulating the intestinal environment and enhancing immunity.

[0026] (3) The product adds probiotic powder to regulate the intestinal environment and improve metabolism. At the same time, the combination of probiotic powder and trehalose has the effect of stabilizing the number of live probiotics during the shelf life.

[0027] (4) Citrus fiber powder, brown algae powder and oat fiber peel extract can supplement dietary fiber, increase satiety, reduce food intake, inhibit fat absorption, promote intestinal peristalsis and improve intestinal flora.

[0028] (5) Hawthorn powder, lotus leaf extract, cassia seed extract, and dried ginger powder are mixed in proportion to help digestion and invigorate the stomach, clear turbidity and reduce lipids, and moisten the intestines and promote bowel movements. They also have the effects of regulating blood sugar, lowering blood lipids, and having anti-oxidation and anti-inflammatory effects.

[0029] (6) Citrus fiber powder, brown algae powder and oat fiber peel extract can supplement dietary fiber, increase satiety, reduce food intake, inhibit fat absorption, promote intestinal peristalsis and improve intestinal flora.

[0030] (7) Taxifolin can inhibit the formation of fatty liver, promote liver cell regeneration, and repair liver damage.

[0031] (8) Oolong tea polypeptides can regulate metabolism, inhibit the activity of fat synthase (such as FAS), reduce the accumulation of triglycerides in the liver, help improve hyperlipidemia, and regulate insulin sensitivity.

[0032] The present invention improves gastrointestinal health, inhibits fat absorption and accumulation, and improves obesity-induced diseases (such as hyperlipidemia, hyperglycemia, and fatty liver). It can assist in the treatment of obesity and also has health benefits for people who want to lose weight and manage their body shape. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are merely embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying any creative work.

[0034] Figure 1 The effect of each sample on the body weight of rats (g, x±s, n=10). DETAILED DESCRIPTION

[0035] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0036] Hawthorn powder was purchased from Shaanxi Kanghe Biotechnology Co., Ltd.; citrus fiber powder was purchased from Shaanxi Yuanzhijin Biotechnology Co., Ltd.; mulberry leaf concentrate powder was purchased from Xi'an Xinlu Biotechnology Co., Ltd.; brown algae powder was purchased from Hubei Sanxin Biotechnology Co., Ltd.; dried ginger powder was purchased from Bozhou Yongxitang Pharmaceutical Co., Ltd.; and oolong tea polypeptide was purchased from Hebei Kelongduo Biotechnology Co., Ltd.

[0037] Example 1

[0038] A method for preparing a psicose special medical food component comprises the following steps:

[0039] (1) 2 parts of Taxol microcapsule powder, 3 parts of hawthorn powder, 2 parts of citrus fiber powder, 2 parts of mulberry leaf concentrate powder, 5 parts of brown algae powder, 0.5 parts of dried ginger powder, 8 parts of resistant dextrin, 5 parts of allulose, and 2 parts of lotus leaf and cassia seed extract were mixed thoroughly in a blender to obtain a mixed powder.

[0040] The preparation method of taxifolin microcapsule powder is as follows: octenyl succinate starch ester: β-cyclodextrin: deionized water are mixed in a mass ratio of 22:8:70, stirred and dissolved in a 70°C water bath, and then cooled; the pH is adjusted to 6 with citric acid, and a colostrum is formed by shearing at 8000 rpm for 5 minutes; the colostrum and taxifolin are mixed in a mass ratio of 20:1, homogenized at a pressure of 30 MPa for 20 minutes, and then pumped into a spray dryer for spray drying at an inlet air temperature of 140°C and a feed rate of 15 rpm. The dried product is taxifolin microcapsule powder.

[0041] The preparation method of the lotus leaf and cassia seed extract is as follows: lotus leaf powder and cassia seed are mixed in a mass ratio of 1:1.5, and steamed at 103°C for 8 minutes; 1 volume of 85% ethanol is added and ground with a grinder, and the residue is filtered through a 300-mesh sieve to obtain the filtrate, which is spray-dried to obtain the lotus leaf and cassia seed extract.

[0042] (2) The mixed powder obtained in step (1) was mixed with the oat fiber peel extract in a weight ratio of 2:5 and subjected to ultrasonic treatment at a power of 300 W and a frequency of 30 kHz for 10 minutes. The ultrasonically treated mixture was subjected to high-speed shearing at 8000 rpm for 10 minutes to form solution A.

[0043] The preparation method of oat fiber skin extract is as follows: the oat fiber skin is crushed, passed through a 60-mesh sieve, and a 0.1 mol / L sodium hydroxide solution is added at a mass ratio of 1:20, and the mixture is reacted at 0.2 MPa and 130°C for 60 minutes; after cooling to room temperature, the mixture is filtered, and the pH of the filtrate is adjusted to 6.0 with a 1% hydrochloric acid solution, 0.2‰ cellulase and 0.1‰ mesophilic amylase are added, the mixture is reacted at 40°C for 20 minutes, and the mixture is boiled for 10 minutes to obtain the oat fiber skin extract; the enzymatic activity of the cellulase is 100,000 U / g; the enzymatic activity of the mesophilic amylase is 100,000 U / mL.

[0044] (3) mixing galactomannan and K carrageenan in a mass ratio of 1:1 to obtain plant colloid;

[0045] (4) 30 parts of coconut oil, 10 parts of oolong tea polypeptide, 1 part of Tween 80 and 2 parts of calcium lactate were mixed and homogenized to form a composite oil emulsion.

[0046] (5) Prepare nutritional powder by adding 55 parts of probiotic powder, 25 parts of trehalose and 30 parts of skim milk powder.

[0047] The preparation method of the probiotic powder is as follows: skim milk powder is diluted with water to a milk protein content of 3.0%, and sterilized at 95°C for 10 minutes to obtain a skim milk powder liquid; a probiotic composition is added to the skim milk powder liquid at a mass ratio of 1:1000, and fermented at 30°C for 12 hours until the acidity reaches 160°T, and then homogenized, quickly frozen, and dried to obtain the probiotic powder;

[0048] The probiotic composition contains 15 parts of plant lactic acid bacteria, 28 parts of Lactobacillus paracasei, 28 parts of Bifidobacterium breve and 15 parts of Lactobacillus bulgaricus; the bacterial concentrations of plant lactic acid bacteria, Lactobacillus paracasei, Bifidobacterium breve and Lactobacillus bulgaricus are all 1.2 trillion CFU / g.

[0049] (6) The plant colloid obtained in step (3) was mixed with solution A prepared in step (2) at a mass ratio of 0.5:100, and the mixture was stirred at 70° C. at a rate of 300 rpm for 1 hour to obtain a colloid solution B.

[0050] (7) The temperature was lowered to 60°C, the composite oil emulsion and glue B were mixed at a weight ratio of 1:50, the pH was adjusted to 5.5 with citric acid buffer, and sheared at 10,000 rpm for 5 minutes to obtain glue C.

[0051] (8) Glue C and nutrient powder were mixed in a mass ratio of 10:1, homogenized for 10 min, added to the mold, and cooled at 5 °C for 30 min to form stable gel particles.

[0052] Example 2

[0053] A method for preparing a psicose special medical food component comprises the following steps:

[0054] (1) 4 parts of Taxol microcapsule powder, 1 part of hawthorn powder, 4 parts of citrus fiber powder, 4 parts of mulberry leaf concentrate powder, 3 parts of brown algae powder, 1 part of dried ginger powder, 4 parts of resistant dextrin, 10 parts of allulose, and 4 parts of lotus leaf and cassia seed extract were mixed thoroughly in a blender to obtain a mixed powder.

[0055] The preparation method of taxifolin microcapsule powder is as follows: octenyl succinate starch ester: β-cyclodextrin: deionized water are mixed in a mass ratio of 22:8:70, stirred and dissolved in a 70°C water bath, and then cooled; the pH is adjusted to 6 with citric acid, and a colostrum is formed by shearing at 8000 rpm for 5 minutes; the colostrum and taxifolin are mixed in a mass ratio of 20:1, homogenized at a pressure of 30 MPa for 20 minutes, and then pumped into a spray dryer for spray drying at an inlet air temperature of 140°C and a feed rate of 15 rpm. The dried product is taxifolin microcapsule powder.

[0056] The preparation method of the lotus leaf and cassia seed extract is as follows: lotus leaf powder and cassia seed are mixed in a mass ratio of 1:1.5, and steamed at 103°C for 15 minutes; 2 times the volume of 85% ethanol is added and ground with a grinder, and the residue is filtered through a 350-mesh sieve to obtain the filtrate, which is spray-dried to obtain the lotus leaf and cassia seed extract.

[0057] (2) The mixed powder obtained in step (1) was mixed with the oat fiber peel extract in a weight ratio of 2:5 and subjected to ultrasonic treatment at a power of 100 W and a frequency of 30 kHz for 5 minutes. The ultrasonically treated mixture was subjected to high-speed shearing at 12,000 rpm for 5 minutes to form solution A.

[0058] The preparation method of oat fiber skin extract is as follows: the oat fiber skin is crushed, passed through a 60-mesh sieve, and a 0.1 mol / L sodium hydroxide solution is added at a mass ratio of 1:20, and the mixture is reacted at 0.2 MPa and 130°C for 60 minutes; after cooling to room temperature, the mixture is filtered, and the pH of the filtrate is adjusted to 5.8 with a 1% hydrochloric acid solution, 0.2‰ cellulase and 0.1‰ mesophilic amylase are added, the mixture is reacted at 40°C for 20 minutes, and the mixture is boiled for 10 minutes to obtain the oat fiber skin extract; the enzymatic activity of the cellulase is 100,000 U / g; the enzymatic activity of the mesophilic amylase is 100,000 U / mL.

[0059] (3) mixing galactomannan and K carrageenan in a mass ratio of 1:1 to obtain plant colloid;

[0060] (4) 50 parts of coconut oil, 5 parts of oolong tea polypeptide, 2 parts of Tween 80 and 4 parts of calcium lactate were mixed and homogenized to form a composite oil emulsion.

[0061] (5) Prepare nutritional powder by adding 45 parts of probiotic powder, 20 parts of trehalose and 35 parts of skim milk powder.

[0062] The preparation method of the probiotic powder is as follows: skim milk powder is diluted with water to a milk protein content of 3.5%, and then sterilized at 98°C for 5 minutes to obtain a skim milk powder liquid; a probiotic composition is added to the skim milk powder liquid at a mass ratio of 1:1000, and fermented at 28°C for 18 hours until the acidity reaches 170°T, and then homogenized, quickly frozen, and dried to obtain the probiotic powder;

[0063] The probiotic composition contains 20 parts of plant lactic acid bacteria, 35 parts of Lactobacillus paracasei, 35 parts of Bifidobacterium breve and 20 parts of Lactobacillus bulgaricus; the bacterial concentrations of plant lactic acid bacteria, Lactobacillus paracasei, Bifidobacterium breve and Lactobacillus bulgaricus are all 1.2 trillion CFU / g.

[0064] (6) The plant colloid obtained in step (3) was mixed with solution A prepared in step (2) at a mass ratio of 0.5:100, and the mixture was stirred at 85° C. at a rate of 500 rpm for 1 hour to obtain a colloid solution B.

[0065] (7) The temperature was lowered to 60°C, the composite oil emulsion and glue B were mixed at a weight ratio of 1:50, the pH was adjusted to 6.5 with citric acid buffer, and sheared at 12000 rpm for 5 min to obtain glue C.

[0066] (8) Glue C and nutrient powder were mixed in a mass ratio of 10:1, homogenized for 10 min, added to the mold, and cooled at 10 °C for 30 min to form stable gel particles.

[0067] Example 3

[0068] A method for preparing a psicose special medical food component comprises the following steps:

[0069] (1) 3 parts of Taxol microcapsule powder, 2 parts of hawthorn powder, 3 parts of citrus fiber powder, 3 parts of mulberry leaf concentrate powder, 4 parts of brown algae powder, 0.7 parts of dried ginger powder, 6 parts of resistant dextrin, 8 parts of allulose, and 3 parts of lotus leaf and cassia seed extract were fully mixed in a blender to obtain a mixed powder.

[0070] The preparation method of taxifolin microcapsule powder is as follows: octenyl succinate starch ester: β-cyclodextrin: deionized water are mixed in a mass ratio of 22:8:70, stirred and dissolved in a 70°C water bath, and then cooled; the pH is adjusted to 6 with citric acid, and a colostrum is formed by shearing at 8000 rpm for 5 minutes; the colostrum and taxifolin are mixed in a mass ratio of 20:1, homogenized at a pressure of 30 MPa for 20 minutes, and then pumped into a spray dryer for spray drying at an inlet air temperature of 140°C and a feed rate of 15 rpm. The dried product is taxifolin microcapsule powder.

[0071] The preparation method of the lotus leaf and cassia seed extract is as follows: lotus leaf powder and cassia seed are mixed in a mass ratio of 1:1.5, and steamed at 103°C for 12 minutes; 1.5 times the volume of 85% ethanol is added and ground with a pulper, filtered with a 320-mesh sieve to remove residue, and the filtrate is spray-dried to obtain the lotus leaf and cassia seed extract.

[0072] (2) The mixed powder obtained in step (1) was mixed with the oat fiber peel extract in a weight ratio of 2:5 and subjected to ultrasonic treatment at a power of 200 W and a frequency of 30 kHz for 8 minutes. The ultrasonically treated mixture was subjected to high-speed shearing at 10,000 rpm for 8 minutes to form solution A.

[0073] The preparation method of oat fiber skin extract is as follows: the oat fiber skin is crushed, passed through a 60-mesh sieve, and a 0.1 mol / L sodium hydroxide solution is added at a mass ratio of 1:20, and the mixture is reacted at 0.2 MPa and 130°C for 60 minutes; after cooling to room temperature, the mixture is filtered, and the filtrate is adjusted to a pH of 5.5 with a 1% hydrochloric acid solution, 0.2‰ cellulase and 0.1‰ mesophilic amylase are added, the mixture is reacted at 40°C for 20 minutes, and the mixture is boiled for 10 minutes to obtain the oat fiber skin extract; the enzymatic activity of the cellulase is 100,000 U / g; the enzymatic activity of the mesophilic amylase is 100,000 U / mL.

[0074] (3) mixing galactomannan and K carrageenan in a mass ratio of 1:1 to obtain plant colloid;

[0075] (4) 40 parts of coconut oil, 7 parts of oolong tea polypeptide, 1.5 parts of Tween 80 and 3 parts of calcium lactate were mixed and homogenized to form a composite oil emulsion.

[0076] (5) Prepare nutritional powder by mixing 50 parts of probiotic powder, 22 parts of trehalose and 33 parts of skim milk powder.

[0077] The preparation method of the probiotic powder is as follows: skim milk powder is diluted with water to a milk protein content of 3.3%, and sterilized at 97°C for 7 minutes to obtain a skim milk powder liquid; a probiotic composition is added to the skim milk powder liquid at a mass ratio of 1:1000, and fermented at 29°C for 15 hours until the acidity reaches 165°T, and then homogenized, quickly frozen, and dried to obtain the probiotic powder;

[0078] The probiotic composition contains 18 parts of plant lactic acid bacteria, 30 parts of Lactobacillus paracasei, 30 parts of Bifidobacterium breve and 18 parts of Lactobacillus bulgaricus; the bacterial concentrations of plant lactic acid bacteria, Lactobacillus paracasei, Bifidobacterium breve and Lactobacillus bulgaricus are all 1.2 trillion CFU / g.

[0079] (6) The plant colloid obtained in step (3) was mixed with solution A prepared in step (2) at a mass ratio of 0.5:100, and the mixture was stirred at 80° C. at a rate of 400 rpm for 1 hour to obtain a colloid solution B.

[0080] (7) The temperature was lowered to 60°C, the composite oil emulsion and glue B were mixed at a weight ratio of 1:50, the pH was adjusted to 6.0 with citric acid buffer, and sheared at 11000 rpm for 5 min to obtain glue C.

[0081] (8) Glue C and nutrient powder were mixed in a mass ratio of 10:1, homogenized for 10 min, added to the mold, and cooled at 8 °C for 30 min to form stable gel particles.

[0082] Comparative Example 1 (without allulose)

[0083] A method for preparing a psicose special medical food component comprises the following steps:

[0084] (1) 2 parts of cyperus ferns microcapsule powder, 3 parts of hawthorn powder, 2 parts of citrus fiber powder, 2 parts of mulberry leaf concentrate powder, 5 parts of brown algae powder, 0.5 parts of dried ginger powder, 8 parts of resistant dextrin, and 2 parts of lotus leaf and cassia seed extract were mixed thoroughly in a blender to obtain a mixed powder.

[0085] The preparation method of taxifolin microcapsule powder is as follows: octenyl succinate starch ester: β-cyclodextrin: deionized water are mixed in a mass ratio of 22:8:70, stirred and dissolved in a 70°C water bath, and then cooled; the pH is adjusted to 6 with citric acid, and a colostrum is formed by shearing at 8000 rpm for 5 minutes; the colostrum and taxifolin are mixed in a mass ratio of 20:1, homogenized at a pressure of 30 MPa for 20 minutes, and then pumped into a spray dryer for spray drying at an inlet air temperature of 140°C and a feed rate of 15 rpm. The dried product is taxifolin microcapsule powder.

[0086] The preparation method of the lotus leaf and cassia seed extract is as follows: lotus leaf powder and cassia seed are mixed in a mass ratio of 1:1.5, and steamed at 103°C for 8 minutes; 1 volume of 85% ethanol is added and ground with a grinder, and the residue is filtered through a 300-mesh sieve to obtain the filtrate, which is spray-dried to obtain the lotus leaf and cassia seed extract.

[0087] (2) The mixed powder obtained in step (1) was mixed with the oat fiber peel extract in a weight ratio of 2:5 and subjected to ultrasonic treatment at a power of 300 W and a frequency of 30 kHz for 10 minutes. The ultrasonically treated mixture was subjected to high-speed shearing at 8000 rpm for 10 minutes to form solution A.

[0088] The preparation method of oat fiber skin extract is as follows: the oat fiber skin is crushed, passed through a 60-mesh sieve, and a 0.1 mol / L sodium hydroxide solution is added at a mass ratio of 1:20, and the mixture is reacted at 0.2 MPa and 130°C for 60 minutes; after cooling to room temperature, the mixture is filtered, and the pH of the filtrate is adjusted to 6.0 with a 1% hydrochloric acid solution, 0.2‰ cellulase and 0.1‰ mesophilic amylase are added, the mixture is reacted at 40°C for 20 minutes, and the mixture is boiled for 10 minutes to obtain the oat fiber skin extract; the enzymatic activity of the cellulase is 100,000 U / g; the enzymatic activity of the mesophilic amylase is 100,000 U / mL.

[0089] (3) mixing galactomannan and K carrageenan in a mass ratio of 1:1 to obtain plant colloid;

[0090] (4) 30 parts of coconut oil, 10 parts of oolong tea polypeptide, 1 part of Tween 80 and 2 parts of calcium lactate were mixed and homogenized to form a composite oil emulsion.

[0091] (5) Prepare nutritional powder by adding 55 parts of probiotic powder, 25 parts of trehalose and 30 parts of skim milk powder.

[0092] The preparation method of the probiotic powder is as follows: skim milk powder is diluted with water to a milk protein content of 3.0%, sterilized at 95°C for 10 minutes to obtain a skim milk powder liquid, a probiotic composition is added to the skim milk powder liquid at a mass ratio of 1:1000, and fermented at 30°C for 12 hours until the acidity reaches 160°T, and then homogenized, quickly frozen, and dried to obtain the probiotic powder;

[0093] The probiotic composition contains 15 parts of plant lactic acid bacteria, 28 parts of Lactobacillus paracasei, 28 parts of Bifidobacterium breve and 15 parts of Lactobacillus bulgaricus; the bacterial concentrations of plant lactic acid bacteria, Lactobacillus paracasei, Bifidobacterium breve and Lactobacillus bulgaricus are all 1.2 trillion CFU / g.

[0094] (6) The plant colloid obtained in step (3) was mixed with solution A prepared in step (2) at a mass ratio of 0.5:100, and the mixture was stirred at 70° C. at a rate of 300 rpm for 1 hour to obtain a colloid solution B.

[0095] (7) The temperature was lowered to 60°C, the composite oil emulsion and glue B were mixed at a weight ratio of 1:50, the pH was adjusted to 5.5 with citric acid buffer, and sheared at 10,000 rpm for 5 minutes to obtain glue C.

[0096] (8) Glue C and nutrient powder were mixed in a mass ratio of 10:1, homogenized for 10 min, added to the mold, and cooled at 5 °C for 30 min to form stable gel particles.

[0097] Comparative Example 2 (no nutritional powder)

[0098] A method for preparing a psicose special medical food component comprises the following steps:

[0099] (1) 2 parts of Taxol microcapsule powder, 3 parts of hawthorn powder, 2 parts of citrus fiber powder, 2 parts of mulberry leaf concentrate powder, 5 parts of brown algae powder, 0.5 parts of dried ginger powder, 8 parts of resistant dextrin, 5 parts of allulose, and 2 parts of lotus leaf and cassia seed extract were mixed thoroughly in a blender to obtain a mixed powder.

[0100] The preparation method of taxifolin microcapsule powder is as follows: octenyl succinate starch ester: β-cyclodextrin: deionized water are mixed in a mass ratio of 22:8:70, stirred and dissolved in a 70°C water bath, and then cooled; the pH is adjusted to 6 with citric acid, and a colostrum is formed by shearing at 8000 rpm for 5 minutes; the colostrum and taxifolin are mixed in a mass ratio of 20:1, homogenized at a pressure of 30 MPa for 20 minutes, and then pumped into a spray dryer for spray drying at an inlet air temperature of 140°C and a feed rate of 15 rpm. The dried product is taxifolin microcapsule powder.

[0101] The preparation method of the lotus leaf and cassia seed extract is as follows: lotus leaf powder and cassia seed are mixed in a mass ratio of 1:1.5, and steamed at 103°C for 8 minutes; 1 volume of 85% ethanol is added and ground with a grinder, and the residue is filtered through a 300-mesh sieve to obtain the filtrate, which is spray-dried to obtain the lotus leaf and cassia seed extract.

[0102] (2) The mixed powder obtained in step (1) was mixed with the oat fiber peel extract in a weight ratio of 2:5 and subjected to ultrasonic treatment at a power of 300 W and a frequency of 30 kHz for 10 minutes. The ultrasonically treated mixture was subjected to high-speed shearing at 8000 rpm for 10 minutes to form solution A.

[0103] The preparation method of oat fiber skin extract is as follows: the oat fiber skin is crushed, passed through a 60-mesh sieve, and a 0.1 mol / L sodium hydroxide solution is added at a mass ratio of 1:20, and the mixture is reacted at 0.2 MPa and 130°C for 60 minutes; after cooling to room temperature, the mixture is filtered, and the pH of the filtrate is adjusted to 6.0 with a 1% hydrochloric acid solution, 0.2‰ cellulase and 0.1‰ mesophilic amylase are added, the mixture is reacted at 40°C for 20 minutes, and the mixture is boiled for 10 minutes to obtain the oat fiber skin extract; the enzymatic activity of the cellulase is 100,000 U / g; the enzymatic activity of the mesophilic amylase is 100,000 U / mL.

[0104] (3) mixing galactomannan and K carrageenan in a mass ratio of 1:1 to obtain plant colloid;

[0105] (4) 30 parts of coconut oil, 10 parts of oolong tea polypeptide, 1 part of Tween 80 and 2 parts of calcium lactate were mixed and homogenized to form a composite oil emulsion.

[0106] (5) The plant colloid obtained in step (3) was mixed with solution A prepared in step (2) at a mass ratio of 0.5:100, and the mixture was stirred at 70° C. at a rate of 300 rpm for 1 hour to obtain a colloid solution B.

[0107] (6) The temperature was lowered to 60°C, the composite oil emulsion and glue B were mixed at a weight ratio of 1:50, the pH was adjusted to 5.5 with citric acid buffer, and sheared at 10,000 rpm for 5 minutes to obtain glue C.

[0108] (7) Glue C was homogenized for 10 min, added to the mold, and cooled at 5°C for 30 min to form stable gel particles.

[0109] Comparative Example 3 (ratio change)

[0110] A method for preparing a psicose special medical food component comprises the following steps:

[0111] (1) 1 part of Taxol microcapsule powder, 4 parts of hawthorn powder, 1 part of citrus fiber powder, 1 part of mulberry leaf concentrate powder, 5 parts of brown algae powder, 2 parts of dried ginger powder, 1 part of resistant dextrin, 3 parts of allulose, and 5 parts of lotus leaf and cassia seed extract were fully mixed in a blender to obtain a mixed powder.

[0112] The preparation method of taxifolin microcapsule powder is as follows: octenyl succinate starch ester: β-cyclodextrin: deionized water are mixed in a mass ratio of 22:8:70, stirred and dissolved in a 70°C water bath, and then cooled; the pH is adjusted to 6 with citric acid, and a colostrum is formed by shearing at 8000 rpm for 5 minutes; the colostrum and taxifolin are mixed in a mass ratio of 20:1, homogenized at a pressure of 30 MPa for 20 minutes, and then pumped into a spray dryer for spray drying at an inlet air temperature of 140°C and a feed rate of 15 rpm. The dried product is taxifolin microcapsule powder.

[0113] The preparation method of the lotus leaf and cassia seed extract is as follows: lotus leaf powder and cassia seed are mixed in a mass ratio of 1:1.5, and steamed at 103°C for 8 minutes; 1 volume of 85% ethanol is added and ground with a grinder, and the residue is filtered through a 300-mesh sieve to obtain the filtrate, which is spray-dried to obtain the lotus leaf and cassia seed extract.

[0114] (2) The mixed powder obtained in step (1) was mixed with the oat fiber peel extract in a weight ratio of 2:5 and subjected to ultrasonic treatment at a power of 300 W and a frequency of 30 kHz for 10 minutes. The ultrasonically treated mixture was subjected to high-speed shearing at 8000 rpm for 10 minutes to form solution A.

[0115] The preparation method of oat fiber skin extract is as follows: the oat fiber skin is crushed, passed through a 60-mesh sieve, and a 0.1 mol / L sodium hydroxide solution is added at a mass ratio of 1:20, and the mixture is reacted at 0.2 MPa and 130°C for 60 minutes; after cooling to room temperature, the mixture is filtered, and the pH of the filtrate is adjusted to 6.0 with a 1% hydrochloric acid solution, 0.2‰ cellulase and 0.1‰ mesophilic amylase are added, the mixture is reacted at 40°C for 20 minutes, and the mixture is boiled for 10 minutes to obtain the oat fiber skin extract; the enzymatic activity of the cellulase is 100,000 U / g; the enzymatic activity of the mesophilic amylase is 100,000 U / mL.

[0116] (3) mixing galactomannan and K carrageenan in a mass ratio of 1:1 to obtain plant colloid;

[0117] (4) 50 parts of coconut oil, 1 part of oolong tea polypeptide, 2 parts of Tween 80 and 1 part of calcium lactate were mixed and homogenized to form a composite oil emulsion.

[0118] (5) Prepare nutritional powder by adding 55 parts of probiotic powder, 5 parts of trehalose and 40 parts of skim milk powder.

[0119] The preparation method of the probiotic powder is as follows: skim milk powder is diluted with water to a milk protein content of 3.0%, sterilized at 95°C for 10 minutes to obtain a skim milk powder liquid, a probiotic composition is added to the skim milk powder liquid at a mass ratio of 1:1000, and fermented at 30°C for 12 hours until the acidity reaches 160°T, and then homogenized, quickly frozen, and dried to obtain the probiotic powder;

[0120] The probiotic composition contains 10 parts of plant lactic acid bacteria, 20 parts of Lactobacillus paracasei, 40 parts of Bifidobacterium breve and 28 parts of Lactobacillus bulgaricus; the bacterial concentrations of plant lactic acid bacteria, Lactobacillus paracasei, Bifidobacterium breve and Lactobacillus bulgaricus are all 1.2 trillion CFU / g.

[0121] (6) The plant colloid obtained in step (3) was mixed with solution A prepared in step (2) at a mass ratio of 0.5:100, and the mixture was stirred at 70° C. at a rate of 300 rpm for 1 hour to obtain a colloid solution B.

[0122] (7) The temperature was lowered to 60°C, the composite oil emulsion and glue B were mixed at a weight ratio of 1:50, the pH was adjusted to 5.5 with citric acid buffer, and sheared at 10,000 rpm for 5 minutes to obtain glue C.

[0123] (8) Glue C and nutrient powder were mixed in a mass ratio of 10:1, homogenized for 10 min, added to the mold, and cooled at 5 °C for 30 min to form stable gel particles.

[0124] Comparative Example 4

[0125] Sample: Allulose.

[0126] Body weight change monitoring experiment--the effect of allulose on body weight.

[0127] Experimental animals: SPF healthy rats were selected, with an initial body weight of 68-82 g. A total of 40 rats, half male and half female, were provided by Beijing Weitonglihua Experimental Animal Technology Co., Ltd.

[0128] Rearing environment: barrier environment animal laboratory, room temperature 20-25℃, relative humidity 40-60%.

[0129] Experimental method: Allulose was added to the rats according to the control (0%) and 4% feeding ratio, and the rats' food intake and body weight were recorded every week for 30 consecutive days.

[0130] The experimental results are shown in Table 1.

[0131] Table 1 Effect of allulose on body weight of normal rats (g, x±s, n=10)

[0132]

[0133] The results in Table 1 showed that allulose could slow down the weight gain of normal rats.

[0134] Test example

[0135] Comparison of weight loss effects of the foods in Examples 1, 2, 3 and Comparative Examples 1, 2, 3, and 4 (4% allulose added to the feed):

[0136] Experimental animals: 80 DIO rats (obese, high sugar) were selected, with initial body weight controlled at 646-672 g.

[0137] Rearing environment: barrier environment animal laboratory, room temperature 20-25℃, relative humidity 40-60%.

[0138] Experimental method: The rats were fed normally every day, and 0.1 g of gel particles were fed at 7:00 and 20:00 every day. The body weight of the rats was recorded every week and the rats were observed for 30 consecutive days.

[0139] The experimental results are shown in Table 2 and Figure 1 .

[0140] Table 2 Effects of each sample on body weight of DIO rats (g, x±s, n=10)

[0141] Shizhong Week 1 Week 2 Week 3 Week 4 Blank control 657±7 661±1 668±3 678±5 684±9 Example 1 659±1 632±7 618±1 604±7 571±5 Example 2 655±3 628±9 614±9 600±3 572±4 Example 3 654±5 627±7 612±4 600±2 571±8 Comparative Example 1 658±3 649±5 644±1 638±9 629±3 Comparative Example 2 657±7 647±5 642±7 631±2 615±1 Comparative Example 3 658±5 645±1 639±3 631±5 618±7 Comparative Example 4 655±9 641±3 629±5 624±9 618±3

[0142] Note: Blank control: normal feeding. Comparative Example 4: 4% psicose was added to the feed.

[0143] The results in Table 2 show that feeding the gel particles of Examples 1, 2, and 3 had a weight loss effect on DOI rats, with a weight loss of approximately 80 g in 4 weeks. Comparative Examples 1, 2, 3, and 4, due to the lack of added psicose, the lack of added nutritional powder, the change in the scientific ratio of ingredients, and the addition of only psicose, had a reduced effect, resulting in a weight loss of only approximately 30 g in 4 weeks.

[0144] The above description of the disclosed embodiments is intended to enable one skilled in the art to implement or use the present invention. Various modifications to these embodiments will be readily apparent to one skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention is not limited to the embodiments shown herein but is intended to conform to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A method for preparing a psicose special medical food component, characterized in that: The following steps are involved: (1) 2-4 parts of Taxusin microcapsule powder, 1-3 parts of hawthorn powder, 2-4 parts of citrus fiber powder, 2-4 parts of mulberry leaf concentrate powder, 3-5 parts of brown algae powder, 0.5-1 part of dried ginger powder, 4-8 parts of resistant dextrin, 5-10 parts of allulose, and 2-4 parts of lotus leaf and cassia seed extract are mixed in a blender to obtain a mixed powder; (2) mixing the mixed powder obtained in step (1) with the oat fiber skin extract in a mass ratio of 2:5 and performing ultrasonic treatment; the ultrasonic treatment conditions are: 100-300 W power, 30 kHz frequency, and treatment for 5-10 minutes; and subjecting the ultrasonically treated mixture to high-speed shearing at 8000-12000 rpm for 5-10 minutes to form solution A; (3) mixing galactomannan and K carrageenan in a mass ratio of 1:1 to obtain a plant colloid; (4) mixing 30-50 parts of coconut oil, 5-10 parts of oolong tea polypeptide, 1-2 parts of Tween 80 and 2-4 parts of calcium lactate, and homogenizing to form a composite oil emulsion; (5) the nutritional powder contains 45-55 parts of probiotic powder, 20-25 parts of trehalose, and 25-40 parts of skim milk powder; (6) mixing the plant colloid obtained in step (3) with solution A prepared in step (2) at a mass ratio of 0.5:100, stirring at 70-85° C. at a rate of 300-500 rpm, and sol-sol for 1 hour to obtain glue solution B; (7) cooling to 60° C., adding the composite oil emulsion prepared in step (4) to the glue solution B, adjusting the pH to 5.5-6.5 with citric acid buffer, and shearing at 10,000-12,000 rpm for 5 minutes to obtain glue solution C; the mass ratio of the glue solution B to the composite oil emulsion is 50:1; (8) Add the nutritional powder obtained in step (5) to the gelatin solution C, homogenize for 10 minutes, add it to the mold, and cool it to 5-10°C to form stable gel particles; the mass ratio of the gelatin solution C to the nutritional powder is 10:

1.

2. The method for preparing a psicose special medical food component according to claim 1, characterized in that: The preparation method of the dihydrotestosterone microcapsule powder in step (1) is as follows: octenyl succinate starch ester: β-cyclodextrin: deionized water are mixed in a mass ratio of 22:8:70, stirred and dissolved in a 70°C water bath, and then cooled; the pH is adjusted to 6 with citric acid, and a colostrum is formed by shearing at 8000 rpm for 5 minutes; the colostrum and dihydrotestosterone are mixed in a mass ratio of 20:1, homogenized at a pressure of 30 MPa for 20 minutes, and then pumped into a spray dryer for spray drying at an inlet air temperature of 140°C and a feed rate of 15 rpm. The dried product is dihydrotestosterone microcapsule powder.

3. The method for preparing a psicose special medical food component according to claim 1, characterized in that: The preparation method of the lotus leaf and cassia seed extract in step (1) is as follows: lotus leaf powder and cassia seed are mixed in a mass ratio of 1:1.5, and steamed at 103°C for 8-15 minutes; 1-2 times the volume of 85% ethanol is added and ground with a pulper, filtered with a 300-350 mesh sieve to remove residue, and the filtrate is spray-dried to obtain the lotus leaf and cassia seed extract.

4. The method for preparing a psicose special medical food component according to claim 1, characterized in that: The preparation method of the oat fiber skin extract in step (2) is as follows: the oat fiber skin is crushed, passed through a 60-mesh sieve, 0.1 mol / L sodium hydroxide solution is added at a mass ratio of 1:20, and the mixture is reacted at 0.2 MPa and 130°C for 60 minutes; after cooling to room temperature, the mixture is filtered, and the filtrate is adjusted to a pH of 5.5-6.0 with a 1% hydrochloric acid solution, 0.2‰ cellulase and 0.1‰ medium-temperature amylase are added, the mixture is reacted at 40°C for 20 minutes, and the mixture is boiled for 10 minutes to obtain the oat fiber skin extract; the enzyme activity of the cellulase is 100,000 U / g; the enzyme activity of the medium-temperature amylase is 100,000 U / mL.

5. The method for preparing a psicose special medical food component according to claim 1, characterized in that: The preparation method of the probiotic powder in step (5) is as follows: diluting skim milk powder with water to a milk protein content of 3.0-3.5%, sterilizing at 95-98°C for 5-10 minutes to obtain a skim milk powder liquid; adding the probiotic composition to the skim milk powder liquid at a mass ratio of 1:1000, fermenting at 28-30°C for 12-18 hours until the acidity reaches 160-170°T, and then homogenizing, quick freezing, and drying to obtain the probiotic powder; The probiotic composition contains 15-20 parts of plant lactic acid bacteria, 28-35 parts of Lactobacillus paracasei, 28-35 parts of Bifidobacterium breve, and 15-20 parts of Lactobacillus bulgaricus; the bacterial concentrations of the plant lactic acid bacteria, Lactobacillus paracasei, Bifidobacterium breve, and Lactobacillus bulgaricus are all 1.2 trillion CFU / g.

6. The psicose special medical food component prepared by the method for preparing the psicose special medical food component according to any one of claims 1 to 5.

7. Use of the allulose special medical food component according to claim 6 in the preparation of a weight loss product.

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