Modularly constructed neurovascular microguide wire

Abstract

The application discloses a modularly composed neurovascular micro guide wire, and relates to the technical field of medical devices. The micro guide wire comprises a first connecting section and a second connecting section, wherein the first connecting section is made of stainless steel, the second connecting section is made of nickel-titanium alloy, the first connecting section and the second connecting section are fixedly welded, the distal end of the second connecting section is provided with an elastic round head, a through hole is formed in the middle of the elastic round head, the end of the second connecting section is provided with a puncture needle, the puncture needle passes through the through hole, the puncture needle is provided with a sharp end, the sharp end is located on the inner side of the through hole, the outer side of the elastic round head and the second connecting section are both provided with a wire winding coil, and the wire winding coil is composed of a nickel-titanium alloy coil and a stainless steel coil which are welded close to the distal end of the micro guide wire. After the elastic round head is pressed against a hard thrombus, the puncture needle is extended out, the hard thrombus is continuously punctured and damaged, and the distal end of the micro guide wire is inserted into the hard thrombus, so that the penetration effect of the micro guide wire is improved, and the micro guide wire can provide a guiding effect for a thrombus stent.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a modularly composed neurovascular microwire. Background Technology

[0002] A microguidewire is a miniature instrument used in interventional diagnosis and treatment of neurovascular diseases. It is typically made of metal (such as stainless steel or nickel-titanium alloy) or composite materials, with a diameter between 0.014 and 0.035 inches. Its tip is flexible, facilitating selective entry into blood vessels; its tail is rigid, providing support. Microguidewires are often used in conjunction with microcatheters to guide and support catheters and other instruments under image guidance, assisting in procedures such as angiography and interventional surgery. They are widely used in the treatment of cerebrovascular and cardiovascular diseases.

[0003] The structure of a microwire determines its function. For example, the microwire in patent publication number CN114618070A includes an inner core, a mesh tube, and a cover layer. The mesh tube is continuously distributed along the axial direction of the inner core and wraps around it. The cover layer is also continuously distributed along the axial direction of the inner core and wraps around and connects the inner core and the mesh tube. The inner core, mesh tube, and cover layer form an integrated structure. In the microwire of this invention, the mesh tube wraps around and connects to the inner core, and the cover layer connects the mesh tube and the inner core. The cover layer and mesh tube can transmit operating torque without affecting the inner core's passage through human tissue. Both the mesh tube and the cover layer are continuously distributed from the proximal to the distal end of the inner core, and there are no solder joints along the axial direction in either the mesh tube or the cover layer. This results in low force transmission loss and solves the problem of poor torque transmission between microwires. Furthermore, the cover layer and mesh tube improve the reliability of the connection between the inner cores and reduce the risk of structural damage to human tissue caused by solder joints or other defects on the inner core surface.

[0004] Microguidewires need to move within blood vessels and from minimally invasive locations to lesion sites, penetrating thrombi and assisting in thrombectomy. However, the distal ends of the aforementioned microguidewires and existing microguidewires are rounded and wound with stainless steel and nickel-titanium alloy coils, making it difficult to penetrate hard thrombi. For thrombectomy of hard thrombi, it is difficult to provide guidance for thrombus stents. Summary of the Invention

[0005] The purpose of this invention is to provide a modularly composed neurovascular microwire to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a modular neurovascular microwire, comprising a first connecting segment and a second connecting segment, wherein the first connecting segment is made of stainless steel and the second connecting segment is made of nickel-titanium alloy, and the first connecting segment and the second connecting segment are welded and fixed together; a telescopic round head is provided at the distal end of the second connecting segment, and a perforation is provided in the middle of the telescopic round head; a puncture needle is provided at the end of the second connecting segment, the puncture needle passes through the perforation, and the puncture needle is provided with a tip located inside the perforation; a wire coil is wound around both the telescopic round head and the outer side of the second connecting segment, and the wire coil is composed of a nickel-titanium alloy coil and a stainless steel coil welded together near the distal end of the microwire.

[0007] Preferably, the outer side of the first connecting section is coated with a polytetrafluoroethylene coating, and the outer side of the winding coil and the telescopic round head is coated with a polyvinylpyrrolidone hydrophilic coating.

[0008] Preferably, the nickel-titanium alloy coil includes a first section, a second section, a third section, and a fourth section. The first section is located outside the telescopic head, the second section is located outside the second connecting section, the third section is integrally formed with the second section and is located outside the puncture needle, and the two ends of the fourth section are fixedly connected to the third section and the end of the first section near the telescopic head, respectively, and the cross-section of the fourth section is flat.

[0009] Preferably, the outer side of the tip is provided with a plurality of circumferentially distributed extension pieces, and the end of the telescopic round head is provided with a plurality of circumferentially distributed extension grooves, and the number of extension grooves is the same as the number of extension pieces.

[0010] Preferably, the inner side of the telescopic round head is provided with a rotating cavity for the extension piece to rotate, and the extension piece is separated from the extension groove, and the outer end of the telescopic round head is provided with a number of circumferentially distributed protrusions.

[0011] Preferably, the puncture needle is rotatably connected to the second connecting section, the outer side of the puncture needle is provided with a spiral pattern, and the inner wall of the telescopic round head is provided with a spiral groove that matches the spiral pattern. The outer end of the telescopic round head is provided with a number of circumferentially distributed anti-slip strips, and the outer side of the tip is provided with a number of circumferentially distributed rotating plates.

[0012] Preferably, the nickel-titanium alloy coil includes a fifth section, a sixth section, and a seventh section. The fifth section is located outside the second connecting section, the sixth section is located outside the telescopic round head, one end of the seventh section is welded and fixed to the second connecting section, and the other end is welded and fixed to the telescopic round head and the sixth section. The seventh section is located inside the fifth section.

[0013] Preferably, a spherical connector is provided at one end of the puncture needle near the second connecting segment, and a spherical cavity is provided inside the second connecting segment. The spherical connector is rotatably disposed in the spherical cavity, and the puncture needle passes through the end of the second connecting segment.

[0014] Preferably, the end of the second connecting segment is provided with a limiting rod, and a limiting hole is opened on the inner side of the telescopic round head, with the limiting hole and the limiting rod being separate.

[0015] Compared with the prior art, the beneficial effects of the present invention are:

[0016] Using a telescopic round tip and a puncture needle, when the telescopic round tip is difficult to penetrate the hard thrombus, the tip of the puncture needle emerges from the perforation and penetrates the hard thrombus through the tip. Under the continuous puncture effect of the tip, the hard thrombus gradually breaks down, and the telescopic round tip can be slowly inserted into the hard thrombus until the microguidewire passes through the hard thrombus. By continuously puncturing and destroying the hard thrombus, the distal end of the microguidewire is inserted into the hard thrombus to provide guidance for the thrombus stent.

[0017] Meanwhile, when the tip pierces a hard thrombus, the extension plate can cut the hard thrombus, enlarge the opening of the hard thrombus, and further facilitate the deep insertion of the retractable round head. Moreover, when the hard thrombus is not pierced, the extension plate is located in the extension groove and will not scratch the blood vessel when the microguidewire moves.

[0018] In addition, when the puncture needle extends outward, the spiral grooves and spiral threads will cause the puncture needle to rotate (at this time, the telescopic round head is pressed against the hard thrombus, and the telescopic round head will not rotate under the action of the anti-slip strip). Under the rotation of the rotating plate, the damaged area of ​​the hard thrombus can be expanded, which further facilitates the passage of the microguidewire. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the overall axonometric structure of the present invention;

[0020] Figure 2 This is a partial cross-sectional view of Embodiment 1 of the present invention;

[0021] Figure 3 For the present invention Figure 1 Schematic diagram of the cross-sectional structure at point A;

[0022] Figure 4 For the present invention Figure 1 Schematic diagram of the cross-sectional structure at point B;

[0023] Figure 5 This is a schematic diagram of the disassembled structure of Embodiment 1 of the present invention;

[0024] Figure 6 This is a partial cross-sectional view of Embodiment 2 of the present invention;

[0025] Figure 7 This is a schematic diagram of the split structure of Embodiment 2 of the present invention.

[0026] In the diagram: 1. First connecting section; 2. Second connecting section; 21. Spherical cavity; 22. Limiting rod; 3. Telescopic round head; 31. Limiting hole; 4. Perforation; 5. Puncture needle; 51. Spherical connector; 6. Winding coil; 61. Nickel-titanium alloy coil; 611. First section; 612. Second section; 613. Third section; 614. Fourth section; 615. Fifth section; 616. Sixth section; 617. Seventh section; 62. Stainless steel coil; 7. Tip; 8. Polytetrafluoroethylene coating; 9. Polyvinylpyrrolidone hydrophilic coating; 10. Extension sheet; 11. Extension groove; 12. Rotating cavity; 13. Raised ridge; 14. Spiral pattern; 15. Spiral groove; 16. Anti-slip strip; 17. Rotating piece. Detailed Implementation

[0027] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0028] Example 1:

[0029] A retractable spike is placed at the distal end of the microguidewire. When it comes into contact with a hard thrombus, the spike can be extended to destroy the hard thrombus, allowing the microguidewire to pass through it.

[0030] like Figures 1-5 As shown, the present invention provides a technical solution: a modular neurovascular microwire, including a first connecting segment 1 and a second connecting segment 2. The first connecting segment 1 is made of stainless steel, and the second connecting segment 2 is made of nickel-titanium alloy. The first connecting segment 1 and the second connecting segment 2 are welded and fixed together. A telescopic round head 3 is provided at the distal end of the second connecting segment 2. A perforation 4 is provided in the middle of the telescopic round head 3. A puncture needle 5 is provided at the end of the second connecting segment 2. The puncture needle 5 passes through the perforation 4 and is provided with a tip 7. The tip 7 is located inside the perforation 4. A wire coil 6 is wound around the outer side of both the telescopic round head 3 and the second connecting segment 2. The wire coil 6 is composed of a nickel-titanium alloy coil 61 and a stainless steel coil 62 welded together near the distal end of the microwire.

[0031] It is important to note that before use, the wire coil 6 and the second connecting section 2 can be bent and shaped to prevent springback. During use, as the microguidewire is inserted deeper, when the telescopic round head 3 is difficult to penetrate the hard thrombus, the operator can continue to push the microguidewire in. At this time, the tip 7 of the puncture needle 5 emerges from the perforation 4 (originally located inside the perforation 4 and will not puncture the blood vessel wall when the microguidewire moves). The tip 7 penetrates the hard thrombus, and then the microguidewire is continuously pushed in and pulled out in small amplitudes. Under the continuous puncture effect of the tip 7, the hard thrombus gradually breaks down, and the telescopic round head 3 can be slowly inserted deeper into the hard thrombus until the microguidewire passes through the hard thrombus. By continuously puncturing and destroying the hard thrombus, the distal end of the microguidewire is inserted into the hard thrombus to provide guidance for the thrombus stent.

[0032] like Figure 3 and Figure 4 As shown, the outer side of the first connecting section 1 is coated with a polytetrafluoroethylene coating 8, and the outer side of the winding coil 6 and the telescopic round head 3 is coated with a polyvinylpyrrolidone hydrophilic coating 9.

[0033] It is important to note that the polytetrafluoroethylene coating 8 reduces friction and enhances corrosion resistance, ensuring smooth and durable guidewire delivery; the polyvinylpyrrolidone hydrophilic coating 9 forms a lubricating film upon contact with water, reducing vascular damage and the risk of thrombosis. The two work together to improve guidewire passability, safety, and operational precision, facilitating complex interventional procedures.

[0034] like Figure 2 As shown, the nickel-titanium alloy coil 61 includes a first section 611, a second section 612, a third section 613, and a fourth section 614. The first section 611 is located outside the telescopic round head 3, the second section 612 is located outside the second connecting section 2, the third section 613 is integrally formed with the second section 612, and the third section 613 is located outside the puncture needle 5. The two ends of the fourth section 614 are fixedly connected to the third section 613 and the end of the first section 611 near the telescopic round head 3, respectively, and the cross-section of the fourth section 614 is flat.

[0035] It should be noted that when the telescopic round head 3 retracts inward, it can compress the fourth section 614. At this time, the first section 611 gradually fits on the outside of the third section 613. When the operator retracts the microguidewire backward, under the action of the fourth section 614, the telescopic round head 3 will advance forward, which can retract the tip 7 into the perforation 4 to prevent puncturing blood vessels.

[0036] like Figure 5 As shown, the outer side of the tip 7 is provided with several circumferentially distributed extension pieces 10, and the end of the telescopic round head 3 is provided with several circumferentially distributed extension grooves 11, and the number of extension grooves 11 is the same as the number of extension pieces 10.

[0037] It should be noted that when the tip 7 pierces the hard thrombus, the extension piece 10 can cut the hard thrombus, enlarge the opening of the hard thrombus, and further facilitate the deep insertion of the retractable round head 3. Moreover, when the hard thrombus is not pierced, the extension piece 10 is located in the extension groove 11 and will not scratch the blood vessel when the microguidewire moves.

[0038] like Figure 5 As shown, the inner side of the telescopic round head 3 is provided with a rotating cavity 12 for the extension piece 10 to rotate, and the extension piece 10 is separated from the extension groove 11. The outer end of the telescopic round head 3 is provided with several circumferentially distributed protrusions 13.

[0039] It should be noted that when the telescopic round head 3 is pressed against the hard thrombus, the operator can rotate the microguidewire. Since the protrusion 13 is pressed against the hard thrombus, the telescopic round head 3 does not rotate at this time, while the puncture needle 5 rotates, which can align the extension piece 10 with the extension groove 11, allowing the extension piece 10 and the tip 7 to extend. Similarly, when not pressed against the hard thrombus, the telescopic round head 3 will rotate synchronously with the puncture needle 5, and the extension piece 10 will never be aligned with the extension groove 11, preventing the tip 7 and the extension piece 10 from protruding and improving the protection of the blood vessel wall.

[0040] Example 2:

[0041] In Example 1, the puncture needle 5 can only perform an insertion operation when puncturing hard thrombi, and the puncture effect is limited. It takes multiple punctures to allow the telescopic round head 3 to penetrate the hard thrombus. This example provides another rotational puncture method to improve the puncture effect.

[0042] like Figure 6 and Figure 7 As shown, the puncture needle 5 is rotatably connected to the second connecting section 2. The outer side of the puncture needle 5 is provided with a spiral pattern 14, and the inner wall of the telescopic round head 3 is provided with a spiral groove 15 that matches the spiral pattern 14. The outer end of the telescopic round head 3 is provided with several circumferentially distributed anti-slip strips 16, and the outer side of the tip 7 is provided with several circumferentially distributed rotating plates 17.

[0043] It should be noted that when the puncture needle 5 extends outward, the spiral groove 14 and spiral groove 15 will cause the puncture needle 5 to rotate (at this time, the telescopic round head 3 is pressed against the hard thrombus, and the telescopic round head 3 will not rotate under the action of the anti-slip strip 16). Under the rotation action of the rotating plate 17, the damaged area of ​​the hard thrombus can be expanded, which further facilitates the passage of the microguidewire.

[0044] like Figure 6As shown, the nickel-titanium alloy coil 61 includes a fifth section 615, a sixth section 616, and a seventh section 617. The fifth section 615 is located outside the second connecting section 2, the sixth section 616 is located outside the telescopic round head 3, one end of the seventh section 617 is welded and fixed to the second connecting section 2, and the other end is welded and fixed to the telescopic round head 3 and the sixth section 616. The seventh section 617 is located inside the fifth section 615.

[0045] It should be noted that when the telescopic round head 3 retracts inward, it can compress the seventh section 617. At this time, the fifth section 615 gradually fits on the outside of the sixth section 616. When the operator retracts the microguidewire backward, under the action of the seventh section 617, the telescopic round head 3 will advance forward, which can retract the tip 7 into the perforation 4 to prevent puncturing blood vessels.

[0046] like Figure 6 As shown, a spherical connector 51 is provided at one end of the puncture needle 5 near the second connecting section 2, and a spherical cavity 21 is provided inside the second connecting section 2. The spherical connector 51 is rotatably disposed in the spherical cavity 21, and the puncture needle 5 passes through the end of the second connecting section 2.

[0047] It should be noted that the spherical connector 51 is located inside the spherical cavity 21, which enables the rotation of the puncture needle 5 and also prevents the puncture needle 5 from falling off.

[0048] like Figure 6 and Figure 7 As shown, a limiting rod 22 is provided at the end of the second connecting section 2, and a limiting hole 31 is opened on the inner side of the telescopic round head 3, with the limiting hole 31 being offset from the limiting rod 22.

[0049] It should be noted that when the limiting hole 31 and the limiting rod 22 are separated, the telescopic round head 3 cannot retract, thereby preventing the tip 7 from scratching the blood vessel wall when the microguidewire moves. When the telescopic round head 3 is pressed against a hard thrombus, the operator must rotate the microguidewire to align the limiting hole 31 with the limiting rod 22 in order to extend the puncture needle 5, thereby improving the protection of the blood vessel wall.

[0050] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended embodiments and their equivalents.

Claims

1. A modularly composed neurovascular microwire, comprising a first connecting segment (1) and a second connecting segment (2), characterized in that: The first connecting section (1) is made of stainless steel, and the second connecting section (2) is made of nickel-titanium alloy. The first connecting section (1) and the second connecting section (2) are welded and fixed together. The distal end of the second connecting section (2) is provided with a telescopic round head (3). The telescopic round head (3) has a perforation (4) in the middle. The end of the second connecting section (2) is provided with a puncture needle (5). The puncture needle (5) passes through the perforation (4). The puncture needle (5) is provided with a tip (7). The tip (7) is located inside the perforation (4). The telescopic round head (3) and the outer side of the second connecting section (2) are both wound with a wire coil (6). The wire coil (6) is composed of a nickel-titanium alloy coil (61) and a stainless steel coil (62) welded together near the distal end of the microguide wire. The puncture needle (5) is rotatably connected to the second connecting section (2). The outer side of the puncture needle (5) is provided with a spiral pattern (14), and the inner wall of the telescopic round head (3) is provided with a spiral groove (15) that matches the spiral pattern (14). The outer end of the telescopic round head (3) is provided with several circumferentially distributed anti-slip strips (16), and the outer side of the tip (7) is provided with several circumferentially distributed rotating plates (17). The nickel-titanium alloy coil (61) includes a fifth section (615), a sixth section (616) and a seventh section (617). The fifth section (615) is located outside the second connecting section (2), the sixth section (616) is located outside the telescopic round head (3), one end of the seventh section (617) is welded and fixed to the second connecting section (2), and the other end is welded and fixed to the telescopic round head (3) and the sixth section (616). The seventh section (617) is located inside the fifth section (615).

2. The modularly composed neurovascular microwire according to claim 1, characterized in that: The outer side of the first connecting section (1) is coated with a polytetrafluoroethylene coating (8), and the outer side of the winding coil (6) and the telescopic round head (3) is coated with a polyvinylpyrrolidone hydrophilic coating (9).

3. The modularly assembled neurovascular microwire according to claim 1, characterized in that: The puncture needle (5) is provided with a spherical connector (51) at one end near the second connecting section (2), and a spherical cavity (21) is provided inside the second connecting section (2). The spherical connector (51) is rotatably disposed in the spherical cavity (21), and the puncture needle (5) passes through the end of the second connecting section (2).

4. The modularly composed neurovascular microwire according to claim 1, characterized in that: The end of the second connecting section (2) is provided with a limiting rod (22), and the inner side of the telescopic round head (3) is provided with a limiting hole (31), which is separated from the limiting rod (22).

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