Multifunctional scribing plate and smear device

By designing a multifunctional streaking and smearing device, automated microbial sample processing is achieved, supporting two streaking methods: inoculation loop and swab, solving the problems of single mode and insufficient space utilization of existing devices, and improving efficiency and accuracy.

CN120758333APending Publication Date: 2025-10-10SHANDONG LUZHEN MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202510966405.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-07-14
Publication Date
2025-10-10

AI Technical Summary

Technical Problem

Existing microbial sample processing devices have a single streaking mode and cannot be flexibly switched, resulting in low streaking efficiency and insufficient utilization of equipment space. In addition, traditional methods require manual transfer of samples, which can easily lead to contamination and affect the accuracy of experimental results.

Method used

A multifunctional streaking and smearing device is designed, which includes a horizontal displacement mechanism, a swab streaking and transport mechanism, an inoculation loop streaking mechanism, and a slide smearing mechanism to realize automated sample processing. It supports both inoculation loop and swab streaking methods, has a high degree of integration, optimizes equipment layout, and reduces repeated circuitous paths.

Benefits of technology

It improves the automation level of sample processing and equipment space utilization, enhances versatility, improves streaking efficiency and the accuracy of experimental results, and reduces manual operation steps and equipment footprint.

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Abstract

The invention provides a multifunctional scribing plate and a smearing device. The problems that an existing microorganism sample treatment device is single in scribing mode, low in scribing efficiency and insufficient in equipment space utilization are solved. Comprising a workbench; a horizontal displacement mechanism is arranged on the working table, an operation table is arranged above the horizontal displacement mechanism in parallel, and an untreated culture dish is placed on the operation table; the moving end of the horizontal displacement mechanism is connected with a first rack and a second rack, and the first rack and the second rack are perpendicular to the operation table. The first rack is in sliding connection with a swab lineation carrying mechanism, and the second rack is in sliding connection with an inoculating loop lineation mechanism; a test tube placing rack and a test tube clamping mechanism are arranged on the workbench, and the swab lineation carrying mechanism is matched with the test tube clamping mechanism to carry and uncover a test tube; and a glass slide smearing mechanism matched with the inoculating loop scribing mechanism for smearing is arranged on the adjacent side of the second rack. The device is widely applied to the technical field of microbiological treatment devices.
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Description

Technical Field

[0001] The present application relates to the technical field of microbial processing devices, and more specifically, to a multifunctional scratching and smearing device. Background Art

[0002] The streaking and smearing of samples are important steps in the isolation, cultivation and detection of microorganisms. Existing microbial sample processing devices mainly use inoculation loops for streaking operations, which has many problems.

[0003] At present, the streaking mode of existing microbial sample processing devices is single and only adaptable to inoculation loop operations. It cannot be flexibly switched according to the sample conditions, making it difficult to meet the increasingly diverse sample processing needs. When processing samples with swabs, the traditional method requires manual transfer of the sample from the swab to the inoculation loop before streaking. The operation steps of this process are cumbersome, requiring a lot of time and manpower costs, and the streaking efficiency is low; and it is easy to cause sample contamination during the sample transfer process, affecting the accuracy of the experimental results. In addition, the functional integration of existing microbial sample processing devices is insufficient, and the layout of various functional modules is scattered. Different independent devices are required to process the culture dishes and slides separately, lacking effective coordination, resulting in an overall large footprint. The equipment space utilization rate is low, and the working paths of each structure are circuitous or overlapping, affecting the stability and work efficiency of the equipment operation. Summary of the Invention In order to solve the above-mentioned existing problems, the technical solution adopted by the present invention is: to provide a multifunctional scribing plate and smear device, which solves the problems of the existing microbial sample processing devices with a single scribing mode, low scribing efficiency and insufficient equipment space utilization. It includes a workbench; a horizontal displacement mechanism is provided on the workbench, and an operating table is provided above the horizontal displacement mechanism in parallel, and an unprocessed culture dish is placed on the operating table; the movable end of the horizontal displacement mechanism is respectively connected to a first frame and a second frame, and the first frame and the second frame are arranged perpendicular to the operating table; a swab scribing and transporting mechanism is slidably connected to the first frame, and an inoculation loop scribing mechanism is slidably connected to the second frame; a test tube placement rack and a test tube clamping mechanism are provided on the workbench, and the swab scribing and transporting mechanism cooperates with the test tube clamping mechanism to transport and open the test tube; a slide smearing mechanism is provided on the adjacent side of the second frame, which cooperates with the inoculation loop scribing mechanism for smearing.

[0004] Preferably, the first frame is provided with a first displacement assembly along the length direction; the swab marking and transporting mechanism includes a first lifting assembly, a rotation drive assembly and a first clamper, the first lifting assembly includes a vertically arranged first lifting drive unit and a mounting bracket, the first lifting drive unit is connected to the moving end of the first displacement assembly, and its output end is connected to the mounting bracket; the mounting bracket is rotatably connected to the first clamper, the rotation drive assembly is fixed on the mounting bracket, and its output end is connected to the first clamper; the first clamper cooperates with the test tube placement rack to clamp the test tube, and cooperates with the test tube clamping mechanism to open the cover of the clamped test tube; when a swab is inserted in the clamped test tube, the first clamper cooperates with the swab on the test tube cover to perform a marking operation on the culture dish on the operating table.

[0005] Preferably, the second frame is provided with a second displacement assembly along the length direction; the inoculation loop marking mechanism includes a vertically arranged second lifting assembly and an inoculation loop, the second lifting assembly is connected to the movable end of the second displacement assembly, and its output end is connected to the inoculation loop, the inoculation loop cooperates with the test tube on the test tube clamping mechanism to perform marking and smear operations on the culture dish on the operating table and the slide on the slide smear mechanism respectively; an infrared sterilizer is provided between the operating table and the slide smear mechanism.

[0006] Preferably, the movable end of the second displacement assembly is also connected to a pipette pump mechanism, which includes a vertically arranged third lifting assembly and a pipette pump. The third lifting assembly is connected to the movable end of the second displacement assembly, and its output end is connected to the pipette pump; a pipette placement rack and a digestion fluid storage cup that cooperate with the pipette pump mechanism are provided under the second frame, and a plurality of pipettes that cooperate with the pipette pump mechanism are provided on the pipette placement rack, and a test tube shaking mechanism for vibrating and mixing the samples in the test tube is provided at the bottom of the test tube placement rack.

[0007] Preferably, the slide smear mechanism includes a slide pushing assembly, a slide conveying assembly vertically distributed with the slide pushing assembly, and a slide storage assembly arranged side by side with the slide pushing assembly; a slide placement rack on which a plurality of slides are stacked is provided above the slide pushing assembly, a slide label printing assembly is provided above the slide placement rack, a paper outlet end of the slide label printing assembly is tilted downward, the slide pushing assembly cooperates with the slide placement rack to push out a single slide, and cooperates with the slide label printing assembly to label the slides; The movable end of the slide conveying assembly is provided with a slide conveying table. The slide pushing assembly cooperates with the slide conveying assembly to push the pushed slide onto the slide conveying table. The slide conveying assembly cooperates with the inoculation loop scribing mechanism to scribing the slide on the slide conveying table. A slide pushing assembly corresponding to the slide storage assembly is provided on the adjacent side of the slide conveying assembly. The slide pushing assembly cooperates with the slide conveying platform to push the slide into the slide storage assembly.

[0008] Preferably, the top surface of the slide rack is provided with a rack chute, the depth of the rack chute is the same as the height of a single slide; the top surface of the slide rack is symmetrically provided with limit blocks for limiting the position of a plurality of stacked slides, the limit blocks cooperate with the rack chute to form a channel for a single slide to pass through; the bottom surface of the slide rack is provided with a rack slide, the rack slide is connected to the rack chute; The slide ejection assembly includes a slide ejection drive unit and a slide ejection plate connected to the output end of the slide ejection drive unit. The slide ejection plate is slidably connected to the slide of the placement rack. The slide ejection plate cooperates with the limit block to push a single slide in the slide of the placement rack to the slide transfer platform. The slide pushing assembly includes a slide pushing drive unit and a slide pushing plate connected to the output end of the slide pushing drive unit. The slide pushing plate cooperates with the slide conveying platform to push the slide into the slide storage assembly.

[0009] Preferably, the horizontal displacement mechanism includes a linear displacement component arranged on the adjacent side of the operating table and two vertically arranged support frames; the linear displacement component includes a linear guide rail arranged along the length direction of the operating table, a linear displacement drive unit and two linear displacement sliders slidably connected to the linear guide rail, and the output end of the linear displacement drive unit is respectively connected to the two linear displacement sliders; the two linear displacement sliders are respectively connected to the two support frames, one support frame is connected to the first frame, and the other support frame is connected to the second frame.

[0010] Preferably, the workbench is further provided with a culture dish placement rack, a culture dish pushing mechanism and a culture dish conveying mechanism. The culture dish conveying mechanism is arranged parallel to and below the operating table. A cover opener is provided between the culture dish placement rack and the operating table. The culture dish pushing mechanism cooperates with the culture dish conveying mechanism to push out a single culture dish and convey it to the operating table. The culture dish pushing mechanism includes a culture dish lifting assembly arranged below the culture dish placement rack and a culture dish clamping assembly arranged adjacent to the culture dish placement rack, and a number of culture dishes are stacked on the culture dish placement rack; the culture dish lifting assembly includes a lifting drive unit vertically arranged on the workbench and a push rod connected to the output end of the lifting drive unit, and the bottom plate of the culture dish placement rack is provided with a through hole for the push rod to pass through; the culture dish clamping assembly includes a clamping drive unit and a second clamper connected to the output end of the clamping drive unit, and the second clamper cooperates with the push rod to clamp some culture dishes.

[0011] Preferably, the culture dish conveying mechanism includes a conveying displacement component and an adsorption component arranged below the operating table, the conveying displacement component includes a conveying guide rail arranged on the workbench, a conveying displacement slider slidingly connected to the conveying guide rail, and a conveying displacement driving unit, and the output end of the conveying displacement driving unit is connected to the conveying displacement slider; the adsorption component includes a vertically arranged adsorption driving unit and a suction cup connected to the output end of the adsorption driving unit, the adsorption driving unit is connected to the conveying displacement slider, and the operating table and the bottom plate of the culture dish placement rack are provided with corresponding through grooves for the suction cup to pass through, the suction cup and the conveying displacement component cooperate to adsorb the culture dish at the bottom plate of the culture dish placement rack and convey the culture dish to the operating table.

[0012] Preferably, the test tube clamping mechanism includes a clamping bracket and a weighing platform arranged on the workbench, the clamping bracket is provided with a third clamper that cooperates with the weighing platform to clamp the test tube, and the weighing platform is provided with a weight sensor for weighing the test tube.

[0013] The beneficial effects of the present invention are as follows: the overall degree of automation of the device is high, and through the cooperation between the various structures, the whole process operation from sample processing to streaking and smearing can be completed. The various structures are arranged in sequence along the culture dish processing process, with clear division of labor and reasonable layout, forming a coherent work path, avoiding repeated detours in the work path, reducing the space occupied by the equipment, improving space utilization and work efficiency, and making the sample processing process smoother. The swab streaking and transporting mechanism can not only realize the transportation and opening of the test tube, cooperate with the inoculation loop streaking mechanism to complete the traditional sample dipping and streaking operations, but also use the swab for independent streaking, so that the device has both inoculation loop streaking and swab streaking methods, which solves the problem that the existing device cannot directly use swabs for streaking, and improves the versatility of the device. The modular design of each functional structure improves the scalability and applicability of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the following briefly introduces the drawings required for use in the embodiments or descriptions of the prior art. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without any creative work.

[0015] Figure 1 It is a structural schematic diagram of the present invention; Figure 2 It is a top view schematic diagram of the present invention; Figure 3 A schematic diagram of the structure of the first rack and the second rack; Figure 4 It is a structural diagram of the swab marking and transporting mechanism; Figure 5It is a structural diagram of the inoculating loop marking mechanism and the pipetting pump mechanism; Figure 6 Schematic diagram of the structure of the slide smear mechanism; Figure 7 Schematic diagram of the structure of the slide push-out assembly; Figure 8 for Figure 7 A partial enlarged view of point A in the middle; Figure 9 This is a structural diagram of the culture dish placement rack and the culture dish pushing mechanism; Figure 10 Schematic diagram of the structure of the culture dish conveying mechanism; Figure 11 It is a structural diagram of the horizontal displacement mechanism; Figure 12 Schematic diagram of the structure of the test tube clamping mechanism.

[0016] Explanation of symbols in the figure: 1. Workbench; 2. Petri dish rack; 3. Petri dish ejection mechanism; 4. Petri dish transport mechanism; 5. Horizontal displacement mechanism; 6. Swab streaking and transport mechanism; 7. Inoculation loop streaking mechanism; 8. Test tube clamping mechanism; 9. Slide smear mechanism; 10. Lid opener; 11. Operating table; 12. First rack; 13. Second rack; 14. Test tube rack; 15. Infrared sterilizer; 16. Pipette pump mechanism; 17. Pipette rack; 18. Digestion fluid storage cup; 19. Test tube oscillation mechanism; 20. Barcode scanner; 21. Label printing and pasting mechanism. 31. Petri dish lifting assembly; 32. Petri dish clamping assembly; 41. Transfer displacement assembly; 42. Adsorption assembly; 51. Linear displacement assembly; 52. Support frame; 61. First lifting assembly; 62. Rotary drive assembly; 63. First clamp; 71. Second lifting assembly; 72. Inoculating loop; 81. Clamping bracket; 82. Weighing platform; 83. Third clamp; 91. Slide ejection assembly; 92. Slide transfer assembly; 93. Slide storage assembly; 94. Slide placement rack; 95. Slide transfer platform; 96. Slide push-in assembly; 97. Slide label printing assembly; 121. First displacement assembly; 131. Second displacement assembly; 161. Third lifting assembly; 162. Pipetting pump; 311. Lifting drive unit; 312. Push rod; 321. Clamping drive unit; 322. Second clamper; 411. Transport guide rail; 412. Transport displacement slider; 413. Transport displacement drive unit; 511. Linear guide rail; 512. Linear displacement drive unit; 513. Linear displacement slider; 611. First lifting drive unit; 612. Mounting bracket; 911. Slide ejection drive unit; 912. Slide ejection plate; 941. Placement rack slide; 942. Limit block; 943. Placement rack slide; 961. Slide push-in drive unit; 962. Slide push-in plate. DETAILED DESCRIPTION

[0017] In order to make the technical problems, technical solutions and beneficial effects to be solved by this application more clearly understood, this application is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain this application and are not intended to limit this application.

[0018] It should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this application.

[0019] It should be noted that the terms "primary" and "secondary" are used for descriptive purposes only and should not be understood to indicate or imply relative importance or implicitly specify the number of technical features indicated. Therefore, features defined as "primary" or "secondary" may explicitly or implicitly include one or more of such features. In the description of this application, "multiple" means two or more, unless otherwise specifically defined.

[0020] A multifunctional scratching plate and smearing device provided in an embodiment of the present application is now described.

[0021] See also Figures 1 to 3 and Figure 9The multifunctional scribing plate and smear device includes a workbench 1, on which is provided a horizontal displacement mechanism 5, and above the horizontal displacement mechanism 5 is provided an operating table 11, on which an untreated culture dish is placed; the movable ends of the horizontal displacement mechanism 5 are respectively connected to a first frame 12 and a second frame 13, and the first frame 12 and the second frame 13 are arranged perpendicular to the operating table 11; the first frame 12 and the second frame 13 are freely movable along the length direction of the operating table 11 under the action of the horizontal displacement mechanism 5. A swab streaking and transporting mechanism 6 is slidably connected to the first frame 12, and an inoculation loop streaking mechanism 7 is slidably connected to the second frame 13. A test tube rack 14 and a test tube clamping mechanism 8 are provided on the workbench 1. The swab streaking and transporting mechanism 6 transports the test tubes on the test tube rack 14 and cooperates with the test tube clamping mechanism 8 to open the cover. A slide smearing mechanism 9 is provided adjacent to the second frame 13, which cooperates with the inoculation loop streaking mechanism 7 to smear.

[0022] In this embodiment, the workbench 1 is further provided with a culture dish rack 2, a culture dish ejection mechanism 3, and a culture dish conveying mechanism 4. The culture dish conveying mechanism 4 is arranged parallel to and below the operating table 11. A lid opener 10 is provided between the culture dish rack 2 and the operating table 11. A number of culture dishes to be processed are stacked on the culture dish rack 2. The culture dish ejection mechanism 3 separates the bottommost culture dish on the culture dish rack 2 from the other culture dishes and cooperates with the culture dish conveying mechanism 4 to eject the separated single culture dish from the culture dish rack 2 and convey it to the operating table 11. During this process, the ejected culture dish is driven by the culture dish conveying mechanism 4 and passes through the lid opener 10 to complete the decapping operation. The decapped culture dish is then placed on the operating table 11 to await subsequent scribing operations.

[0023] Specifically, when a sample is placed in a test tube, the swab marking and transporting mechanism 6 clamps the test tube from the test tube rack 14 and transports it to the test tube clamping mechanism 8. The test tube clamping mechanism 8 secures the test tube. The swab marking and transporting mechanism 6 uncaps the test tube and removes the test tube cap. The inoculation loop marking and transporting mechanism 7 moves over to dip the sample in the test tube. The inoculation loop marking and transporting mechanism 7 can then be moved above the operating table 11 to mark the culture dish on the operating table 11, or moved to the slide smearing mechanism 9 to smear the slide. When a swab is inserted into a test tube, the swab marking and transporting mechanism 6 clamps the test tube from the test tube rack 14 and transports it to the test tube clamping mechanism 8. The test tube clamping mechanism 8 secures the test tube. The swab marking and transporting mechanism 6 uncaps the test tube. The swab, along with the test tube cap, is transported by the swab marking and transporting mechanism 6 to the operating table 11 to mark the culture dish on the operating table 11. The swab marking and transporting mechanism 6 can not only realize the transportation and opening of the test tube, cooperate with the inoculation loop marking mechanism 7 to complete the traditional sample dipping and marking operations, but also use the swab for independent marking, so that the device has both inoculation loop marking and swab marking methods, which solves the problem that the existing device cannot directly use swabs for marking, and improves the versatility of the device.

[0024] See also Figures 1 to 4 Furthermore, the first frame 12 is provided with a first displacement assembly 121 along its length. The swab streaking and transporting mechanism 6 includes a first lifting assembly 61, a rotary drive assembly 62, and a first clamper 63. The first lifting assembly 61 includes a vertically arranged first lifting drive unit 611 and a mounting bracket 612. The first lifting drive unit 611 is connected to the movable end of the first displacement assembly 121, and its output end is connected to the mounting bracket 612. The mounting bracket 612 is rotationally connected to the first clamper 63. The rotary drive assembly 62 is fixed to the mounting bracket 612, and its output end is connected to the first clamper 63. The first clamper 63 cooperates with the test tube placement rack 14 to clamp the test tube and cooperates with the test tube clamping mechanism 8 to open the cap of the clamped test tube. When a swab is inserted into the clamped test tube, the first clamper 63 cooperates with the swab on the test tube cap to perform a streaking operation on the culture dish on the operating table 11. In this embodiment, the first lifting drive unit 611 is a drive device including but not limited to a cylinder or a linear motor.

[0025] When the swab line carrying mechanism 6 is working, the horizontal displacement mechanism 5 and the first displacement assembly 121 are matched to drive the swab line carrying mechanism 6 to move above the test tube rack 14, the first lifting driving unit 611 is started, the output end drives the installation support 612 and the first gripper 63 to move synchronously to the appropriate height, and the first gripper 63 clamps the test tube in the test tube rack 14. After clamping, the first lifting driving unit 611 drives the first gripper 63 to move upwards, and under the cooperation of the horizontal displacement mechanism 5 and the first displacement assembly 121, the first gripper 63 carries the test tube to the test tube clamping mechanism 8, and after the test tube is placed in the test tube clamping mechanism 8, the test tube clamping mechanism 8 fixes the test tube. If the inoculation loop line method is used, the swab line carrying mechanism 6 uncovers the test tube and moves the test tube cover away to avoid the subsequent inoculation loop line mechanism 7 to dip the sample. If the swab line method is used, the swab line carrying mechanism 6 uncovers the test tube, and then moves the swab head connected with the test tube cover to above the operation table 11; then, the rotary driving assembly 62 is started to drive the first gripper 63 to rotate, so as to adjust the angle of the swab head, so that the swab head contacts and lines the surface of the culture dish at an appropriate angle. The rotary driving assembly 62 adjusts the angle of the swab head to ensure that the swab can evenly smear the sample during the line operation, thereby improving the stability of the line operation and the accuracy of the detection result.

[0026] Please refer to Figures 1 to 5 , further, the second rack 13 is provided with a second displacement assembly 131 along the length direction; the inoculation loop line mechanism 7 comprises a vertical second lifting assembly 71 and an inoculation loop 72, the output end of the second lifting assembly 71 is connected with the moving end of the second displacement assembly 131, and the output end is connected with the inoculation loop 72, the inoculation loop 72 cooperates with the test tube on the test tube clamping mechanism 8 to perform line and smear operations on the culture dish on the operation table 11 and the glass slide on the glass slide smearing mechanism 9 respectively; the infrared sterilizer 15 is arranged between the operation table 11 and the glass slide smearing mechanism 9, and is used for pre-disinfecting the inoculation loop line mechanism 7.

[0027] Furthermore, the movable end of the second displacement assembly 131 is also connected to a pipette pump mechanism 16, which includes a vertically arranged third lifting assembly 161 and a pipette pump 162. The third lifting assembly 161 is connected to the movable end of the second displacement assembly 131, and its output end is connected to the pipette pump 162. Below the second frame 13 are provided a pipette rack 17 and a digestion fluid storage cup 18 that cooperate with the pipette pump mechanism 16. The pipette rack 17 is equipped with multiple pipettes that cooperate with the pipette pump mechanism 16. The bottom of the test tube rack 14 is provided with a test tube shaking mechanism 19 that vibrates and mixes the sample in the test tube. If the sample in the test tube is sputum, it needs to be diluted with digestion fluid before dipping. After the test tube is placed in the test tube clamping mechanism 8, the test tube clamping mechanism 8 secures the test tube. The pipette pump mechanism 16 is activated to draw digestive fluid from the digestive fluid storage cup 18. With the cooperation of the horizontal displacement mechanism 5 and the second displacement assembly 131, the pipette pump mechanism 16 moves above the test tube clamping mechanism 8 and drips the digestive fluid into the tube to be tested, completing the dilution of the sputum sample. In this embodiment, the second lifting assembly 71 and the third lifting assembly 161 are drive devices including but not limited to cylinders or linear motors.

[0028] See also Figure 1 、 Figure 2 and Figure 6 Furthermore, the slide smear mechanism 9 includes a slide pushing component 91, a slide conveying component 92 vertically distributed with the slide pushing component 91, and a slide storage component 93 arranged side by side with the slide pushing component 91; a slide placement rack 94 on which a plurality of slides are stacked is provided above the slide pushing component 91, a slide label printing component 97 is provided above the slide placement rack 94, and a paper outlet end of the slide label printing component 97 is tilted downward, the slide pushing component 91 cooperates with the slide placement rack 94 to push out a single slide, and cooperates with the slide label printing component 97 to label the slide; The movable end of the slide transport assembly 92 is provided with a slide transport platform 95. The slide push assembly 91 cooperates with the slide transport assembly 92 to push the pushed slide onto the slide transport platform 95. The slide transport assembly 92 cooperates with the inoculation loop scribing mechanism 7 to scribing the slide on the slide transport platform 95. A slide pushing assembly 96 corresponding to the slide storage assembly 93 is provided adjacent to the slide transport assembly 92 . The slide pushing assembly 96 cooperates with the slide transport platform 95 to push the slide into the slide storage assembly 93 .

[0029] The smearing process of the device is as follows: the slide pushing-out assembly 91 is first started, and the lowermost slide on the slide placing rack 94 is pushed out to the slide conveying table 95. In this process, the slide pushing-out assembly 91 cooperates with the slide label printing assembly 97 to perform the labeling operation on the pushed-out slide. Subsequently, the inoculating loop lineation mechanism 7 after sample dipping moves above the slide conveying table 95 under the cooperation of the horizontal displacement mechanism 5 and the second displacement assembly 131 to perform the smearing operation on the slide. After the smearing operation is completed, the slide conveying assembly 92 drives the slide conveying table 95 to move to the front side of the slide pushing-in assembly 96, and the slide pushing-in assembly 96 is started to push the slide on the slide conveying table 95 into the slide storage assembly 93 to orderly store the slide.

[0030] Please refer to Figure 1 、 Figure 2 and Figures 6 to 8 Further, the top surface of the slide placing rack 94 is provided with a placing rack sliding groove 941, the depth of the placing rack sliding groove 941 is the same as the height of a single slide; the top surface of the slide placing rack 94 is symmetrically provided with limiting blocks 942 limiting the stacking of a plurality of slides, the limiting blocks 942 cooperate with the placing rack sliding groove 941 to form a channel for a single slide to pass through, ensuring that only the lowermost slide is located in the placing rack sliding groove 941 each time; the bottom surface of the slide placing rack 94 is provided with a placing rack sliding channel 943, which is in communication with the placing rack sliding groove 941; The slide pushing-out assembly 91 comprises a slide pushing-out driving unit 911 and a slide pushing-out plate 912 connected with the output end of the slide pushing-out driving unit 911, and the slide pushing-out plate 912 is in sliding connection with the placing rack sliding channel 943; the slide pushing-out plate 912 cooperates with the limiting blocks 942 to push the single slide in the placing rack sliding groove 941 out to the slide conveying table 95; The slide pushing-in assembly 96 comprises a slide pushing-in driving unit 961 and a slide pushing-in plate 962 connected with the output end of the slide pushing-in driving unit 961, and the slide pushing-in plate 962 cooperates with the slide conveying table 95 to push the slide into the slide storage assembly 93. In the embodiment, the slide pushing-in driving unit 961 is a driving device including but not limited to a pneumatic cylinder or a linear motor.

[0031] When a slide needs to be pushed out, the slide push-out drive unit 911 is activated, driving the slide push-out plate 912 to slide along the rack slide 943; during the sliding process, the slide push-out plate 912 cooperates with the limit block 942 to push out a single slide in the rack slide 941, while the remaining slides are limited by the limit block 942. Under the push of the slide push-out plate 912, the slide is pushed onto the slide transfer table 95 to await subsequent smearing operations. After the smearing operation is completed, the slide transfer assembly 92 is activated, driving the slide transfer table 95 to move to the front side of the slide push-in assembly 96. The slide push-in drive unit 961 drives the slide push-in plate 962 forward, and the slide push-in plate 962 cooperates with the slide transfer table 95 to push the slide that has completed the smearing operation into the slide storage assembly 93.

[0032] See also Figures 1 to 3 and Figure 11 Specifically, the horizontal displacement mechanism 5 includes a linear displacement component 51 arranged on the adjacent side of the operating table 11 and two vertically arranged support frames 52; the linear displacement component 51 includes a linear guide rail 511 arranged along the length direction of the operating table 11, a linear displacement drive unit 512 and two linear displacement sliders 513 slidingly connected to the linear guide rail 511, and the output end of the linear displacement drive unit 512 is respectively connected to the two linear displacement sliders 513; the two linear displacement sliders 513 are respectively connected to the two support frames 52, one support frame 52 is connected to the first frame 12, and the other support frame 52 is connected to the second frame 13.

[0033] See also Figure 1 、 Figure 2 and Figure 9 Specifically, the culture dish pushing mechanism 3 includes a culture dish lifting assembly 31 arranged below the culture dish rack 2 and a culture dish clamping assembly 32 arranged adjacent to the culture dish rack 2, and a number of culture dishes are stacked on the culture dish rack 2; the culture dish lifting assembly 31 includes a lifting drive unit 311 vertically arranged on the workbench 1 and a push rod 312 connected to the output end of the lifting drive unit 311, and the bottom plate of the culture dish rack 2 is provided with a through hole for the push rod 312 to pass through; the culture dish clamping assembly 32 includes a clamping drive unit 321 and a second clamper 322 connected to the output end of the clamping drive unit 321, and the second clamper 322 cooperates with the push rod 312 to clamp some culture dishes.

[0034] See also Figure 1 、 Figure 2 、 Figure 9 and Figure 10Specifically, the culture dish conveying mechanism 4 includes a conveying displacement assembly 41 and an adsorption assembly 42 disposed below the operating table 11. The conveying displacement assembly 41 includes a conveying guide rail 411 disposed on the workbench 1, a conveying displacement slider 412 slidably connected to the conveying guide rail 411, and a conveying displacement drive unit 413. The output end of the conveying displacement drive unit 413 is connected to the conveying displacement slider 412. The adsorption assembly 42 includes a vertically disposed adsorption drive unit and a suction cup connected to the output end of the adsorption drive unit. The adsorption drive unit is connected to the conveying displacement slider 412. The operating table 11 and the bottom plate of the culture dish rack 2 are both provided with corresponding through grooves for the suction cup to pass through. The suction cup and the conveying displacement assembly 41 cooperate to adsorb the lowest culture dish on the bottom plate of the culture dish rack 2 and transfer the culture dish to the operating table 11. In this embodiment, the lifting drive unit 311 and the adsorption drive unit are drive devices including but not limited to cylinders or linear motors.

[0035] The process of pushing out the culture dish is as follows: the lifting drive unit 311 is started, the driving push rod 312 is moved upward, and the culture dishes stacked on the culture dish rack 2 are lifted upward through the through hole until the height of the second-to-last culture dish from top to bottom corresponds to the culture dish clamping assembly 32. At this time, the clamping drive unit 321 is started, and the second clamper 322 is driven to clamp and fix some of the culture dishes except the bottom culture dish. The lifting drive unit 311 is started, and the driving push rod 312 is moved downward, and the bottom culture dish falls together to the bottom plate of the culture dish rack 2 and is separated from the other culture dishes above. Subsequently, the adsorption drive unit is started, and the suction cup contacts and adsorbs the culture dish through the through slot; the transmission displacement drive unit 413 is started, and the transmission displacement slider 412 and the adsorption assembly 42 are driven to slide along the transmission guide rail 411 to complete the pushing out of a single culture dish.

[0036] Specifically, in this embodiment, the lid opener 10 is a structure with two through ends and an open bottom. It has symmetrical opening slots on both sides, and the height of the bottom of the opening slots gradually increases along the direction of the culture dish's movement. The culture dish conveyor mechanism 4 drives the culture dish into the lid opener 10. The lid of the culture dish first contacts the bottom of the lower opening slot. As the culture dish moves, the lid is gradually lifted upward along the inclined opening slot. When the culture dish completely passes through the lid opener 10, the lid is successfully lifted and detached from the culture dish, achieving automatic lid removal.

[0037] See also Figure 1 、 Figure 2 and Figure 12Specifically, the test tube clamping mechanism 8 comprises a clamping bracket 81 and a weighing platform 82 mounted on the workbench 1. The clamping bracket 81 is equipped with a third clamper 83 that cooperates with the weighing platform 82 to hold the test tube. The weighing platform 82 is internally provided with a weight sensor for weighing the test tube. When the test tube is clamped and secured by the third clamper 83, the weight sensor within the weighing platform 82 weighs the test tube. The weighing data is then transmitted to the control system, which is used to determine the amount of digestive fluid added by the pipetting pump mechanism 16 to prevent over- or under-addition.

[0038] See also Figure 1 and Figure 2 Specifically, a barcode scanner 20 is provided between the test tube placement rack 14 and the test tube clamping mechanism 8. When the swab marking and transporting mechanism 6 clamps the test tube, the barcode scanner 20 reads the test tube information in a timely manner.

[0039] See also Figure 1 Specifically, a test tube oscillation mechanism 19 is provided at the bottom of the test tube rack 14. The test tube oscillation mechanism 19 includes an oscillation motor and an eccentric shaft connected to the output end of the oscillation motor. The eccentric shaft is rotatably connected to the bottom surface of the test tube rack 14. When the test tube after the digestive fluid is added is returned to the test tube rack 14, the oscillation motor starts, driving the eccentric shaft to rotate, causing the test tube rack 14 to vibrate regularly, fully mixing the sputum and digestive fluid in the test tube. After the mixture is evenly mixed, the oscillation motor stops rotating. This part of the structure is prior art and will not be described in detail here.

[0040] See also Figure 1 and Figure 2 Specifically, a label printing and pasting mechanism 21 is provided adjacent to the operating table 11. The label printing and pasting mechanism 21 includes a labeling fixing bracket arranged on the workbench 1, a label reel and a label printer which are sequentially arranged on the labeling fixing bracket. A horizontally placed label roll is provided on the label reel, and one end of the label roll is connected to the label printer; the paper outlet of the label printer pushes out the label vertically, and the pushing direction of the label is perpendicular to the operating table 11, and the label is matched with the side of the culture dish on the operating table 11 for labeling.

[0041] In this embodiment, a turntable mechanism is provided on the bottom surface of the bottom plate of the culture dish rack 2 , and the turntable mechanism drives the culture dish rack 2 to rotate. This is a prior art and will not be described in detail here.

[0042] In this embodiment, the first displacement assembly 121 is a belt transmission mechanism composed of a driving pulley, a driven pulley, a synchronous belt, and a drive motor, and the synchronous belt is connected to the first lifting drive unit 611. The second displacement assembly 131 is also a belt transmission mechanism, and the synchronous belt is connected to the second lifting assembly 71 and the third lifting assembly 161, respectively.

[0043] The rotary drive assembly 62 is also a belt transmission mechanism, and the driven wheel shaft is connected to the first clamper 63 .

[0044] The slide ejection drive unit 911 is also a belt transmission mechanism, and its synchronous belt is connected to the slide ejection plate 912; the slide conveying assembly 92 has a similar structure to the slide ejection drive unit 911, and is also a belt transmission mechanism, and its synchronous belt is connected to the slide conveying platform 95.

[0045] The linear displacement driving unit 512 is also a belt transmission mechanism, and the synchronous belt is connected to the two linear displacement sliders 513 respectively.

[0046] The transmission displacement driving unit 413 is also a belt transmission mechanism, and its synchronous belt is connected to the transmission displacement slider 412. The above belt transmission mechanisms are all existing technologies and will not be described in detail here.

[0047] The clamping drive unit 321 is a gear rack transmission mechanism composed of components such as a gear, a rack and a drive motor, and the rack is connected to the second clamper 322; the belt transmission mechanism and the gear rack transmission mechanism are existing technologies and will not be described in detail here.

[0048] The working process of this device for marking a culture dish is as follows: 1. Pretreatment stage: First, the culture dish pushing mechanism 3 separates the lowest culture dish on the culture dish rack 2 from the other culture dishes; then the culture dish conveying mechanism 4 is started, driving the culture dish to be uncapped through the decapping device 10, and the uncapped culture dish is conveyed to the operating table 11 to wait for marking.

[0049] 2. Sample Processing Stage: Swab streaking and transporting mechanism 6, working in conjunction with horizontal displacement mechanism 5 and first displacement assembly 121, moves to the top of test tube rack 14. First gripper 63 moves downward to grasp a test tube and transport it to test tube clamping mechanism 8, which secures the tube. Swab streaking and transporting mechanism 6 then uncaps the test tube and removes the cap.

[0050] (1) If a normal sample is placed in the test tube, the inoculation loop marking mechanism 7 moves over to dip the sample in cooperation with the horizontal displacement mechanism 5 and the second displacement assembly 131.

[0051] (2) If a swab is inserted into the test tube, the swab marking and transporting mechanism 6 opens the cover of the test tube and then transports the test tube cover and the swab together to the top of the operating table 11.

[0052] (3) When the test tube sample is sputum, after the swab marking and transporting mechanism 6 opens the cover of the test tube, the pipetting pump mechanism 16, in cooperation with the horizontal displacement mechanism 5 and the second displacement component 131, draws the digestive fluid from the digestive fluid storage cup 18 and drips it into the test tube to complete the dilution.

[0053] 3. Line smear operation stage: (1) If an inoculation loop is used for marking, the inoculation loop marking mechanism 7 after dipping the sample is moved to the top of the operating table 11 to mark the culture dish or to the slide smear mechanism 9 in cooperation with the horizontal displacement mechanism 5 and the second displacement component 131.

[0054] (2) If a swab is used for marking, the swab marking transport mechanism 6 adjusts the angle of the swab head by rotating the drive assembly 62 above the operating table 11 and then marks the culture dish.

[0055] The working process of this device for smearing slides is as follows: Slide ejection assembly 91 pushes the bottom slide from slide rack 94 onto slide transfer platform 95, where it awaits streaking. The sample processing steps are identical to those for streaking a Petri dish. The inoculating loop streaking mechanism 7, which dips the sample, coordinates with the horizontal displacement mechanism 5 and the second displacement assembly 131 to move it above slide transfer platform 95 for smearing.

[0056] In the present invention, the overall degree of automation of the device is high, and through the cooperation between the various structures, the whole process operation from sample processing to marking and smearing can be completed. The various structures are arranged in sequence along the culture dish processing process, with clear division of labor and reasonable layout, forming a coherent work path, avoiding repeated circuitous work paths, reducing the space occupied by the equipment, improving space utilization and work efficiency, and making the sample processing process smoother. The swab marking and transporting mechanism 6 can not only realize the transportation and opening of the test tube, cooperate with the inoculation loop marking mechanism 7 to complete the traditional sample dipping and marking operations, but also use the swab for independent marking, so that the device has both inoculation loop marking and swab marking methods, solving the problem that the existing device cannot directly use swabs for marking, and improving the versatility of the device. The modular design of each functional structure improves the scalability and applicability of the device.

[0057] The above specific implementation methods do not cover the entire scope of protection of this application. Modifications or equivalent replacements of the invention should all fall within the scope of the patent coverage of this application. In the present invention, the above embodiments are only used to illustrate the technical solutions of this application, rather than to limit them. Although this application has been described in detail with reference to the above embodiments, a person of ordinary skill in the art should understand that it is still possible to modify the technical solutions described in the above embodiments, or to replace some of the technical features therein. These modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of this application, and should all be included in the scope of protection of this application.

Claims

1. A multifunctional scribing and smearing device, including a workbench, characterized in that: The workbench is provided with a horizontal displacement mechanism, and an operating table is provided parallel to the above-mentioned horizontal displacement mechanism, on which an untreated culture dish is placed; the movable ends of the horizontal displacement mechanism are respectively connected to a first frame and a second frame, and the first frame and the second frame are vertically distributed to the operating table; a swab streaking and transporting mechanism is slidably connected to the first frame, and an inoculation loop streaking mechanism is slidably connected to the second frame; a test tube placement rack and a test tube clamping mechanism are provided on the workbench, and the swab streaking and transporting mechanism cooperates with the test tube clamping mechanism to transport and open the test tube; a slide smearing mechanism is provided on the adjacent side of the second frame for cooperating with the inoculation loop streaking mechanism for smearing.

2. A multifunctional scribing and smearing device according to claim 1, characterized in that: The first frame is provided with a first displacement assembly along the length direction; the swab streaking and transporting mechanism includes a first lifting assembly, a rotary drive assembly and a first clamper, the first lifting assembly includes a vertically arranged first lifting drive unit and a mounting bracket, the first lifting drive unit is connected to the moving end of the first displacement assembly, and its output end is connected to the mounting bracket; the mounting bracket is rotatably connected to the first clamper, the rotary drive assembly is fixed on the mounting bracket, and its output end is connected to the first clamper; the first clamper cooperates with the test tube placement rack to clamp the test tube, and cooperates with the test tube clamping mechanism to open the cover of the clamped test tube; when a swab is inserted in the clamped test tube, the first clamper cooperates with the swab on the test tube cover to perform a streaking operation on the culture dish on the operating table.

3. The multifunctional scribing and smearing device according to claim 1, characterized in that: The second frame is provided with a second displacement assembly along the length direction; the inoculation loop marking mechanism includes a vertically arranged second lifting assembly and an inoculation loop, the second lifting assembly is connected to the moving end of the second displacement assembly, and its output end is connected to the inoculation loop, the inoculation loop cooperates with the test tube on the test tube clamping mechanism to perform marking and smear operations on the culture dish on the operating table and the slide on the slide smear mechanism respectively; an infrared sterilizer is provided between the operating table and the slide smear mechanism.

4. A multifunctional scribing and smearing device according to claim 3, characterized in that: The movable end of the second displacement assembly is also connected to a pipette pump mechanism, which includes a vertically arranged third lifting assembly and a pipette pump. The third lifting assembly is connected to the movable end of the second displacement assembly, and its output end is connected to the pipette pump. A pipette placement rack and a digestion fluid storage cup that cooperate with the pipette pump mechanism are provided below the second frame. The pipette placement rack is provided with a plurality of pipettes that cooperate with the pipette pump mechanism. A test tube oscillation mechanism for vibrating and mixing the samples in the test tubes is provided at the bottom of the test tube placement rack.

5. The multifunctional scribing and smearing device according to claim 1, characterized in that: The slide smear mechanism includes a slide pushing assembly, a slide conveying assembly vertically distributed with the slide pushing assembly, and a slide storage assembly arranged side by side with the slide pushing assembly; a slide placement rack on which a plurality of slides are stacked is provided above the slide pushing assembly, a slide label printing assembly is provided above the slide placement rack, and a paper outlet end of the slide label printing assembly is tilted downward; the slide pushing assembly cooperates with the slide placement rack to push out a single slide and cooperates with the slide label printing assembly to label the slide; The movable end of the slide transport assembly is provided with a slide transport platform, the slide pushing assembly cooperates with the slide transport assembly to push the pushed-out slide onto the slide transport platform, and the slide transport assembly cooperates with the inoculation loop scribing mechanism to scribing the slide on the slide transport platform; A slide pushing assembly corresponding to the slide storage assembly is provided adjacent to the slide conveying assembly, and the slide pushing assembly cooperates with the slide conveying platform to push the slide into the slide storage assembly.

6. A multifunctional scribing and smearing device according to claim 5, characterized in that: The top surface of the slide rack is provided with a rack slide groove, the depth of the rack slide groove is the same as the height of a single slide; the top surface of the slide rack is symmetrically provided with limit blocks for limiting the position of a plurality of stacked slides, the limit blocks cooperate with the rack slide groove to form a channel for a single slide to pass through; the bottom surface of the slide rack is provided with a rack slide, the rack slide is connected to the rack slide groove; The slide ejection assembly includes a slide ejection drive unit and a slide ejection plate connected to the output end of the slide ejection drive unit, the slide ejection plate being slidably connected to the slide of the placement rack; the slide ejection plate cooperates with the limit block to eject a single slide in the slide trough of the placement rack to the slide conveying platform; The slide pushing assembly includes a slide pushing drive unit and a slide pushing plate connected to the output end of the slide pushing drive unit. The slide pushing plate cooperates with the slide conveying platform to push the slide into the slide storage assembly.

7. The multifunctional scribing and smearing device according to claim 1, characterized in that: The horizontal displacement mechanism includes a linear displacement component arranged on the adjacent side of the operating table and two vertically arranged support frames; the linear displacement component includes a linear guide rail arranged along the length direction of the operating table, a linear displacement drive unit and two linear displacement sliders slidably connected to the linear guide rails, and the output end of the linear displacement drive unit is respectively connected to the two linear displacement sliders; the two linear displacement sliders are respectively connected to the two support frames, one of the support frames is connected to the first frame, and the other support frame is connected to the second frame.

8. The multifunctional scribing and smearing device according to claim 1, characterized in that: The workbench is also provided with a culture dish placement rack, a culture dish pushing mechanism and a culture dish conveying mechanism. The culture dish conveying mechanism is arranged parallel to and below the operating table. A cover opener is provided between the culture dish placement rack and the operating table. The culture dish pushing mechanism cooperates with the culture dish conveying mechanism to push out a single culture dish and convey it to the operating table. The culture dish pushing mechanism includes a culture dish lifting assembly arranged below the culture dish placement rack and a culture dish clamping assembly arranged adjacent to the culture dish placement rack, and a number of culture dishes are stacked on the culture dish placement rack; the culture dish lifting assembly includes a lifting drive unit vertically arranged on the workbench and a push rod connected to the output end of the lifting drive unit, and the bottom plate of the culture dish placement rack is provided with a through hole for the push rod to pass through; the culture dish clamping assembly includes a clamping drive unit and a second clamper connected to the output end of the clamping drive unit, and the second clamper cooperates with the push rod to clamp part of the culture dishes.

9. The multifunctional scribing and smearing device according to claim 8, characterized in that: The culture dish conveying mechanism includes a conveying displacement component and an adsorption component arranged below the operating table, the conveying displacement component includes a conveying guide rail arranged on the workbench, a conveying displacement slider slidingly connected to the conveying guide rail, and a conveying displacement driving unit, the output end of the conveying displacement driving unit is connected to the conveying displacement slider; the adsorption component includes a vertically arranged adsorption driving unit and a suction cup connected to the output end of the adsorption driving unit, the adsorption driving unit is connected to the conveying displacement slider, the operating table and the bottom plate of the culture dish placement rack are both provided with corresponding through grooves for the suction cup to pass through, the suction cup and the conveying displacement component cooperate to adsorb the lowest culture dish on the bottom plate of the culture dish placement rack and convey the culture dish to the operating table.

10. The multifunctional scribing and smearing device according to claim 1, characterized in that: The test tube clamping mechanism includes a clamping bracket and a weighing platform arranged on the workbench. The clamping bracket is provided with a third clamper that cooperates with the weighing platform to clamp the test tube. The weighing platform is provided with a weight sensor for weighing the test tube.