Long-acting deodorizing shampoo and preparation method thereof

Abstract

The preparation method comprises the following steps: mixing and dissolving pure water and EDTA-2Na (Ethylene Diamine Tetraacetic Acid), heating to 60-90 DEG C, adding K12A and cocamidopropyl betaine, and stirring and mixing; naturally cooling to 20-50 DEG C, adding nano tourmaline powder, silk fibroin hydrolysate, persimmon tannin extract, D-panthenol, glycerol, polyquaternium-10, Kathon and sodium chloride, and stirring and mixing; and adjusting the pH value to 4.5-7.0, and continuously stirring to obtain the long-acting deodorizing shampoo. Based on the synergistic effect of the silk fibroin, the tourmaline powder and the persimmon extract, multi-dimensional long-acting control over peculiar smell is achieved through physical antibacterial barrier contact blocking, negative ion targeted decomposition of peculiar smell and tannic acid radical source oxidation resistance, meanwhile, drug resistance, irritation and micro-ecological damage risks of a traditional technology are avoided, and the preparation method is simple and convenient to operate. And a safer, more stable and more adaptive deodorizing solution is provided for the elderly.

Description

Technical Field

[0001] This invention relates to the field of shampoo preparation technology, specifically to a long-lasting deodorizing shampoo and its preparation method. Background Technology

[0002] Elderly people are prone to volatile odors (such as nonenal and short-chain fatty acids) due to the degeneration of sebaceous gland function, changes in sweat secretion composition, and imbalance of scalp flora. Traditional deodorizing shampoos suffer from several technical challenges. First, they typically rely on single broad-spectrum antibacterial agents like zinc pyrithione (ZPT). Long-term use not only accelerates the selection of drug-resistant strains but also disrupts the scalp's microecological balance, increasing the risk of irritant contact dermatitis. Second, odor intervention strategies are limited to superficial masking, using synthetic fragrances to temporarily cover odor molecules without inhibiting the sebum oxidation chain reaction. Furthermore, the polarity between aldehydes and ester fragrances can amplify the odor. Third, insufficient stability of active ingredients is a technological bottleneck. For example, aldehyde dehydrogenase is easily deactivated at pH > 6.5 or high temperatures, and natural antioxidants like tea polyphenols become ineffective due to photosensitivity and quinone conversion, shortening the product's effective period after opening to 3-6 months. Finally, the cleansing system is unbalanced. Strong anionic surfactants (such as sodium lauryl sulfate / SLS) excessively degrease, damaging the skin barrier and triggering compensatory sebum secretion, while milder surfactants like amino acids or APGs leave oxidized lipid residues due to insufficient detergency.

[0003] The above issues collectively hinder breakthroughs in shampoo products in terms of odor control, safety, and age-friendliness. Therefore, it is of great significance to research and develop a safe and effective odor-removing shampoo that eliminates odors from the source. Summary of the Invention

[0004] This invention addresses the shortcomings of existing technologies by providing a long-lasting deodorizing shampoo and its preparation method. Based on the synergistic effect of silk fibroin, tourmaline powder, and persimmon extract, it achieves multi-dimensional and long-lasting control of "old people's smell" through physical antibacterial barrier blocking contact, negative ion targeted decomposition of odor, and tannic acid root-cause anti-oxidation. At the same time, it avoids the risks of drug resistance, irritation, and microecological damage of traditional technologies, providing a safer, more stable, and more adaptable deodorizing solution for the elderly.

[0005] To address the aforementioned technical problems, the first aspect of this invention provides a method for preparing a long-lasting deodorizing shampoo, comprising the following steps:

[0006] S1. Dissolve pure water and EDTA-2Na in a mixture, heat to 60-90℃, add K12A and cocamidopropyl betaine, and stir to mix.

[0007] S2. Allow to cool naturally to 20-50℃, then add nano tourmaline powder, silk fibroin hydrolysate, persimmon tannin extract, D-panthenol, glycerin, polyquaternium-10, Kathon and sodium chloride, and stir to mix.

[0008] S3. Adjust the pH to 4.5-7.0, continue stirring, and obtain the long-lasting deodorizing shampoo.

[0009] This invention, based on the synergistic effect of silk fibroin, tourmaline powder, and persimmon extract, achieves multi-dimensional and long-lasting control of "old people's smell" through physical antibacterial barrier blocking contact, negative ion targeted decomposition of odor, and tannin-based antioxidant activity. It also avoids the risks of drug resistance, irritation, and microecological damage associated with traditional technologies, providing a safer, more stable, and more adaptable odor removal solution for the elderly. Specifically:

[0010] By adding silk fibroin to form a breathable protective film on the scalp surface, sebum oxidation is reduced (the activity of sebaceous glands is low in the elderly, and oxidation easily produces odor molecules such as aldehydes and ketones); silk fibroin is rich in hydrophilic amino acids such as glycine and serine, which maintain the scalp's hydration and reduce compensatory sebum secretion caused by dryness; in addition, silk fibroin forms a hydrogen bond network through an ordered β-sheet conformation (NH···O=C, bond energy about 25kJ / mol), which preferentially adsorbs odor molecules containing polar functional groups (such as aldehydes and hydroxyl groups) based on the principle of polarity matching. This process achieves the initial capture and spatial enrichment of odor molecules through intermolecular directional forces.

[0011] The surface of nano-tourmaline carries a permanent negative charge due to crystal structure defects. This negative charge, combined with Coulomb attraction, causes electrostatic adsorption of positively charged odor ions (such as protonated amines), forming a locally high-concentration adsorption layer. Simultaneously, this process synergizes with the physical adsorption of silk fibroin, constructing a dual molecular trap of hydrogen bonds and electrostatics, significantly enhancing the enrichment efficiency of odor molecules at the interface of the composite system. Furthermore, the spontaneous polarization effect of tourmaline generates a micro-electric field (approximately 10⁻⁶ Ω·cm). 3 -10 4 The adsorbed water layer is activated through the interfacial charge transfer process (V / m), which promotes the electrolysis of water molecules to generate ·OH free radicals (redox potential 2.8V). These active species directly attack the functional groups of adsorbed odor molecules (such as aldehyde C=O bond and amino NH bond), triggering an oxidative decomposition reaction. The adsorbed and enriched odor molecules migrate directionally to the active sites on the tourmaline surface under the action of a micro electric field, shortening the mass transfer distance and reducing the reaction activation energy through electric field induction.

[0012] The tannic acid (containing a polyhydroxyphenolic structure) in persimmon tannin extract initiates a nucleophilic attack on the aldehyde C atom of 2-nonenal via the phenolic hydroxyl oxygen atom, generating a stable acetal / hemiacetal derivative, thus achieving the chemical decomposition of odor molecules. Simultaneously, the tourmaline micro-electric field acts as an electron donor, injecting electrons into the oxidized tannin (quinone structure), prompting its reduction and regeneration into the phenolic structure through a single-electron transfer process. This cyclical mechanism maintains the continuous catalytic activity of tannic acid, avoiding efficiency degradation due to oxidative deactivation.

[0013] Furthermore, the silk fibroin hydrolysate and nano-tourmaline together construct a "hydrogen bond-electrostatic" dual molecular trap, achieving the adsorption of odor molecules and odor ions.

[0014] Furthermore, the tourmaline micro-electric field injects electrons into the oxidized tannin, causing it to be reduced and regenerated into a reduced phenolic structure, thus maintaining the continuous catalytic activity of tannic acid.

[0015] Furthermore, by weight percentage, the shampoo comprises the following ingredients:

[0016] EDTA-2Na (disodium ethylenediaminetetraacetate): 0.05%–0.5%;

[0017] K12A (ammonium lauryl sulfate): 1-10%;

[0018] Cocamidopropyl betaine: 3%–8%;

[0019] Nano tourmaline powder: 0.5%–3%;

[0020] Silk fibroin hydrolysate: 1%–5%;

[0021] Persimmon tannin extract: 0.5%–2.5%;

[0022] D-Panthenol: 0.1%–1%;

[0023] Glycerin: 2%–5%;

[0024] Polyquaternium-10: 0.5%–1.5%;

[0025] Kathon: 0.1–0.5%;

[0026] Sodium chloride: 0.5–3%;

[0027] The remainder consists of pH adjuster and water.

[0028] Furthermore, the molecular weight of the silk fibroin hydrolysate is ≤10kDa.

[0029] Furthermore, in S3, the pH is adjusted using a citrate buffer solution.

[0030] Furthermore, in S3, the stirring time is 10-30 minutes.

[0031] Furthermore, the preparation method of the silk fibroin hydrolysate is as follows:

[0032] (1) Place the silk in a sodium carbonate aqueous solution and treat it at 70-100℃ for 30-60 minutes, then wash it until it is neutral and dry it; wherein, the mass concentration of the sodium carbonate aqueous solution is 0.5%-2%;

[0033] (2) The dried silk is crushed and distilled water is added and stirred to obtain a suspension;

[0034] (3) Adjust the pH of the suspension to 8-9 using sodium hydroxide solution and raise the temperature to 45-55℃;

[0035] (4) Add trypsin, stir and react, then sterilize and filter to obtain silk fibroin hydrolysate.

[0036] Furthermore, in step (2), the amount of silk added to the suspension is 2wt%-10wt%, the stirring speed is 150-200r / min, and the time is 10-15min.

[0037] Furthermore, in step (4), the amount of trypsin added is 1%-5% of the weight of the silk, and the stirring speed is 100-200 r / min.

[0038] Furthermore, in step (4), the sterilization temperature is 90-100℃ and the time is 10-15min.

[0039] The second aspect of this invention provides a long-lasting deodorizing shampoo prepared by the method described in the first aspect. The beneficial effects of this invention are:

[0040] This invention is based on the synergistic effect of silk fibroin, tourmaline powder, and persimmon extract. It achieves multi-dimensional and long-term control of "old people's smell" by blocking contact with the body through physical antibacterial barrier, decomposing odors with negative ions, and providing antioxidant protection from the root cause of tannins. At the same time, it avoids the risks of drug resistance, irritation, and microecological damage of traditional technologies, providing a safer, more stable, and more adaptable odor removal solution for the elderly.

[0041] This invention utilizes a dual molecular trap of "hydrogen bond-electrostatic" structure, constructed by combining silk fibroin hydrolysate and nano-tourmaline, to adsorb odor molecules and odor ions.

[0042] This invention injects electrons into oxidized tannins through a tourmaline micro-electric field, causing them to be reduced and regenerated into a reduced phenolic structure, thus maintaining the continuous catalytic activity of tannic acid. Attached Figure Description

[0043] To more clearly illustrate the technical solution of the present invention, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0044] Figure 1 This invention is a hair combing force test before and after using the shampoo in Example 1 and Comparative Example 1;

[0045] Figure 2 This invention relates to the tensile strength test of hair strands before and after using the shampoo in Example 1 and Comparative Example 1.

[0046] Figure 3 This invention relates to a hair shine test before and after using the shampoo in Example 1 and Comparative Example 1.

[0047] Figure 4 This invention relates to the inhibition rate test of Malassezia after using shampoos from Examples 1, 2, and 3. Detailed Implementation

[0048] The technical solution of the present invention will be clearly and completely described below with reference to specific embodiments. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0049] This embodiment relates to a method for preparing a long-lasting deodorizing shampoo, comprising the following steps:

[0050] S1. Dissolve pure water and EDTA-2Na in a mixture, heat to 60-90℃, add K12A and cocamidopropyl betaine, and stir to mix.

[0051] S2. Allow to cool naturally to 20-50℃, then add nano tourmaline powder, silk fibroin hydrolysate, persimmon tannin extract, D-panthenol, glycerin, polyquaternium-10, Kathon and sodium chloride, and stir to mix.

[0052] S3. Adjust the pH to 4.5-7.0, continue stirring, and obtain the long-lasting deodorizing shampoo.

[0053] This invention is based on the synergistic effect of silk fibroin, tourmaline powder, and persimmon extract. It achieves multi-dimensional and long-term control of "old people's smell" by blocking contact with the body through physical antibacterial barrier, decomposing odors with negative ions, and providing antioxidant protection from the root cause of tannins. At the same time, it avoids the risks of drug resistance, irritation, and microecological damage of traditional technologies, providing a safer, more stable, and more adaptable odor removal solution for the elderly.

[0054] Specifically, the hydrolysate of silk fibroin and nano-tourmaline jointly construct a dual molecular trap of "hydrogen bond-electrostatic" to achieve the adsorption of odor molecules and odor ions; the micro-electric field of tourmaline injects electrons into the oxidized tannin, causing it to be reduced and regenerated into the reduced phenolic structure, thus maintaining the continuous catalytic activity of tannic acid.

[0055] In a preferred embodiment, the shampoo comprises the following ingredients by weight percentage:

[0056] EDTA-2Na (disodium ethylenediaminetetraacetate): 0.05%–0.5%;

[0057] K12A (ammonium lauryl sulfate): 1-10%;

[0058] Cocamidopropyl betaine: 3%–8%;

[0059] Nano tourmaline powder: 0.5%–3%;

[0060] Silk fibroin hydrolysate: 1%–5%;

[0061] Persimmon tannin extract: 0.5%–2.5%;

[0062] D-Panthenol: 0.1%–1%;

[0063] Glycerin: 2%–5%;

[0064] Polyquaternium-10: 0.5%–1.5%;

[0065] Kathon: 0.1–0.5%;

[0066] Sodium chloride: 0.5–3%;

[0067] The remainder consists of pH adjuster and water.

[0068] In a preferred embodiment, the molecular weight of the silk fibroin hydrolysate is ≤10kDa.

[0069] In a preferred embodiment, in step S3, the pH is adjusted using a citrate buffer solution; in step S3, the stirring time is 10-30 minutes.

[0070] As a preferred embodiment, the method for preparing the silk fibroin hydrolysate is as follows:

[0071] (1) Place the silk in a sodium carbonate aqueous solution and treat it at 70-100℃ for 30-60 minutes, then wash it until it is neutral and dry it; wherein, the mass concentration of the sodium carbonate aqueous solution is 0.5%-2%;

[0072] (2) The dried silk is crushed and distilled water is added and stirred to obtain a suspension;

[0073] The amount of silk added to the suspension is 2wt%-10wt%, the stirring speed is 150-200r / min, and the time is 10-15min;

[0074] (3) Adjust the pH of the suspension to 8-9 using sodium hydroxide solution and raise the temperature to 45-55℃;

[0075] (4) Add trypsin, stir and react, then sterilize and filter to obtain silk fibroin hydrolysate;

[0076] The amount of trypsin added is 1%-5% of the weight of the silk, and the stirring speed is 100-200 r / min; the sterilization temperature is 90-100℃ and the time is 10-15 min.

[0077] Another embodiment provides a long-lasting deodorizing shampoo prepared by the preparation method described in the above embodiments.

[0078] Preparation Example

[0079] This preparation example relates to the preparation of a silk fibroin hydrolysate, specifically including the following steps:

[0080] (1) Immerse the silk completely in a 1% sodium carbonate aqueous solution, place it in a water bath, boil it at 100°C for 30 minutes, remove the silk, rinse it repeatedly with distilled water until the pH of the rinsing solution is close to 7, and place it in a cool and ventilated place to dry for later use.

[0081] (2) Pulverize the dried silk and transfer it to a clean reaction vessel. Add distilled water at a concentration of 5% silk protein and stir with a magnetic stirrer at 200 r / min for 10 minutes to form a uniform suspension.

[0082] (3) The pH of the suspension was precisely adjusted to 8.5 using a 1 mol / L sodium hydroxide solution. Then the reaction vessel was transferred to a constant temperature water bath, heated to 50°C, and kept at a constant temperature.

[0083] (4) Weigh out trypsin at 2% of the amount of silk fibroin protein, slowly add it to the reaction system, stir thoroughly for 5 minutes to ensure that the enzyme and substrate are evenly mixed, turn on the stirring device and keep the speed at 100r / min.

[0084] (5) The reaction system was rapidly heated to 95°C and maintained for 15 minutes to deactivate the enzyme by using the high-temperature enzyme inactivation method. Under sterile conditions, impurities in the hydrolysis product were filtered out to obtain silk fibroin hydrolysate, which was used as the raw material component for subsequent examples and comparative examples.

[0085] Example 1

[0086] This embodiment relates to a method for preparing a long-lasting deodorizing shampoo, comprising the following steps:

[0087] Add pure water to the reaction vessel, then add 0.05 parts of EDTA-2Na, and turn on the stirrer until completely dissolved. After the temperature inside the reaction vessel rises to 80℃, add 1 part of K12A and 5 parts of cocamidopropyl betaine in sequence and stir evenly. After the temperature drops to 45℃, add 2 parts of nano tourmaline powder, 3 parts of silk fibroin hydrolysate, 1.5 parts of persimmon tannin extract, 0.5 parts of D-panthenol, 3 parts of glycerin, 0.8 parts of polyquaternium-10, 0.3 parts of Kathon, and 1 part of sodium chloride. After stirring evenly at low temperature, slowly add citrate buffer solution with a pH of 6, and add pure water until the total weight of the shampoo is 100 parts to obtain a long-lasting deodorizing shampoo.

[0088] Example 2

[0089] The difference between this embodiment and Example 1 is that the amount of nano-tourmaline powder is 0.5 parts, the amount of silk fibroin hydrolysate is 1 part, and the amount of persimmon tannin extract is 0.5 parts. Other parameters and steps remain unchanged. Specifically:

[0090] Add pure water to the reaction vessel, then add 0.05 parts of EDTA-2Na, and turn on the stirrer until completely dissolved. After the temperature inside the reaction vessel rises to 80℃, add 1 part of K12A and 5 parts of cocamidopropyl betaine in sequence and stir evenly. After the temperature drops to 45℃, add 0.5 parts of nano tourmaline powder, 1 part of silk fibroin hydrolysate, 0.5 parts of persimmon tannin extract, 0.5 parts of D-panthenol, 3 parts of glycerin, 0.8 parts of polyquaternium-10, 0.3 parts of Kathon, and 1 part of sodium chloride. Stir evenly at low temperature, then slowly add citrate buffer solution with a pH of 6, and add pure water until the total weight of the shampoo is 100 parts to obtain a long-lasting deodorizing shampoo.

[0091] Example 3

[0092] The difference between this embodiment and Embodiment 2 is that the silk fibroin hydrolysate is in two parts, while other parameters and steps remain unchanged. Specifically:

[0093] Add pure water to the reaction vessel, then add 0.05 parts of EDTA-2Na, and turn on the stirrer until completely dissolved. After the temperature inside the reaction vessel rises to 80℃, add 1 part of K12A and 5 parts of cocamidopropyl betaine in sequence and stir evenly. After the temperature drops to 45℃, add 0.5 parts of nano tourmaline powder, 2 parts of silk fibroin hydrolysate, 0.5 parts of persimmon tannin extract, 0.5 parts of D-panthenol, 3 parts of glycerin, 0.8 parts of polyquaternium-10, 0.3 parts of Kathon, and 1 part of sodium chloride. Stir evenly at low temperature, then slowly add citrate buffer solution with a pH of 6, and add pure water until the total weight of the shampoo is 100 parts to obtain a long-lasting deodorizing shampoo.

[0094] Example 4

[0095] The difference between this embodiment and Embodiment 2 is that the silk fibroin hydrolysate is in two parts, while other parameters and steps remain unchanged. Specifically:

[0096] Add pure water to the reaction vessel, then add 0.05 parts of EDTA-2Na, and turn on the stirrer until completely dissolved. After the temperature inside the reaction vessel rises to 80℃, add 1 part of K12A and 5 parts of cocamidopropyl betaine in sequence and stir evenly. After the temperature drops to 45℃, add 0.5 parts of nano tourmaline powder, 3 parts of silk fibroin hydrolysate, 0.5 parts of persimmon tannin extract, 0.5 parts of D-panthenol, 3 parts of glycerin, 0.8 parts of polyquaternium-10, 0.3 parts of Kathon, and 1 part of sodium chloride. Stir evenly at low temperature, then slowly add citrate buffer solution with a pH of 6, and add pure water until the total weight of the shampoo is 100 parts to obtain a long-lasting deodorizing shampoo.

[0097] Example 5

[0098] The difference between this embodiment and Embodiment 4 is that the amount of nano-tourmaline powder is 1 part, while other parameters and steps remain unchanged. Specifically:

[0099] Add pure water to the reaction vessel, then add 0.05 parts of EDTA-2Na, and turn on the stirrer until completely dissolved. After the temperature inside the reaction vessel rises to 80℃, add 1 part of K12A and 5 parts of cocamidopropyl betaine in sequence and stir evenly. After the temperature drops to 45℃, add 1 part of nano tourmaline powder, 3 parts of silk fibroin hydrolysate, 0.5 parts of persimmon tannin extract, 0.5 parts of D-panthenol, 3 parts of glycerin, 0.8 parts of polyquaternium-10, 0.3 parts of Kathon, and 1 part of sodium chloride. Stir evenly at low temperature, then slowly add citrate buffer solution with a pH of 6, and add pure water until the total weight of the shampoo is 100 parts to obtain a long-lasting deodorizing shampoo.

[0100] Example 6

[0101] The difference between this embodiment and Example 1 is that the silk fibroin hydrolysate is 5 parts and the persimmon tannin extract is 1 part, while other parameters and steps remain unchanged. Specifically:

[0102] Add pure water to the reaction vessel, then add 0.05 parts of EDTA-2Na, and turn on the stirrer until completely dissolved. After the temperature inside the reaction vessel rises to 80℃, add 1 part of K12A and 5 parts of cocamidopropyl betaine in sequence and stir evenly. After the temperature drops to 45℃, add 2 parts of nano tourmaline powder, 5 parts of silk fibroin hydrolysate, 1 part of persimmon tannin extract, 0.5 parts of D-panthenol, 3 parts of glycerin, 0.8 parts of polyquaternium-10, 0.3 parts of Kathon, and 1 part of sodium chloride. Stir evenly at low temperature, then slowly add citrate buffer solution with a pH of 6, and add pure water until the total weight of the shampoo is 100 parts to obtain a long-lasting deodorizing shampoo.

[0103] Example 7

[0104] The difference between this embodiment and Example 1 is that the amount of nano-tourmaline powder is 3 parts and the amount of persimmon tannin extract is 1 part, while other parameters and steps remain unchanged. Specifically:

[0105] Add pure water to the reaction vessel, then add 0.05 parts of EDTA-2Na, and turn on the stirrer until completely dissolved. After the temperature inside the reaction vessel rises to 80℃, add 1 part of K12A and 5 parts of cocamidopropyl betaine in sequence and stir evenly. After the temperature drops to 45℃, add 3 parts of nano tourmaline powder, 3 parts of silk fibroin hydrolysate, 1 part of persimmon tannin extract, 0.5 parts of D-panthenol, 3 parts of glycerin, 0.8 parts of polyquaternium-10, 0.3 parts of Kathon, and 1 part of sodium chloride. Stir evenly at low temperature, then slowly add citrate buffer solution with a pH of 6, and add pure water until the total weight of the shampoo is 100 parts to obtain a long-lasting deodorizing shampoo.

[0106] Comparative Example 1

[0107] The difference between this comparative example and Example 1 is that the silk fibroin hydrolysate is 0.5 parts, while other parameters and steps remain unchanged, specifically:

[0108] Add pure water to the reaction vessel, then add 0.05 parts of EDTA-2Na, and turn on the stirrer until completely dissolved. After the temperature inside the reaction vessel rises to 80℃, add 1 part of K12A and 5 parts of cocamidopropyl betaine in sequence and stir evenly. After the temperature drops to 45℃, add 2 parts of nano tourmaline powder, 0.5 parts of silk fibroin hydrolysate, 1.5 parts of persimmon tannin extract, 0.5 parts of D-panthenol, 3 parts of glycerin, 0.8 parts of polyquaternium-10, 0.3 parts of Kathon, and 1 part of sodium chloride. Stir evenly at low temperature, then slowly add citrate buffer solution with a pH of 6, and add pure water until the total weight of the shampoo is 100 parts to obtain the deodorizing shampoo.

[0109] Comparative Example 2

[0110] The difference between this comparative example and Example 1 is that the persimmon tannin extract is in 3 parts, while other parameters and steps remain unchanged, specifically:

[0111] Add pure water to the reaction vessel, then add 0.05 parts of EDTA-2Na, and turn on the stirrer until completely dissolved. After the temperature inside the reaction vessel rises to 80℃, add 1 part of K12A and 5 parts of cocamidopropyl betaine in sequence and stir evenly. After the temperature drops to 45℃, add 2 parts of nano tourmaline powder, 3 parts of silk fibroin hydrolysate, 3 parts of persimmon tannin extract, 0.5 parts of D-panthenol, 3 parts of glycerin, 0.8 parts of polyquaternium-10, 0.3 parts of Kathon, and 1 part of sodium chloride. Stir evenly at low temperature, then slowly add citrate buffer solution with a pH of 6, and add pure water until the total weight of the shampoo is 100 parts to obtain the deodorizing shampoo.

[0112] Comparative Example 3

[0113] The difference between this comparative example and Example 1 is that the amount of nano-tourmaline powder is 0.3 parts, while other parameters and steps remain unchanged. Specifically:

[0114] Add pure water to the reaction vessel, then add 0.05 parts of EDTA-2Na, and turn on the stirrer until completely dissolved. After the temperature inside the reaction vessel rises to 80℃, add 1 part of K12A and 5 parts of cocamidopropyl betaine in sequence and stir evenly. After the temperature drops to 45℃, add 0.3 parts of nano tourmaline powder, 3 parts of silk fibroin hydrolysate, 1.5 parts of persimmon tannin extract, 0.5 parts of D-panthenol, 3 parts of glycerin, 0.8 parts of polyquaternium-10, 0.3 parts of Kathon, and 1 part of sodium chloride. Stir evenly at low temperature, then slowly add citrate buffer solution with a pH of 6, and add pure water until the total weight of the shampoo is 100 parts to obtain the deodorizing shampoo.

[0115] Test case

[0116] (1) Hair combing ability test

[0117] Combing force tests were performed on hair before and after using the shampoo from Example 1 and Comparative Example 1, respectively. The results are as follows: Figure 1 The results show that, compared to Comparative Example 1, hair treated with the shampoo of Example 1 exhibits significantly reduced combing resistance, resulting in smoother and easier-to-comb hair. This is because silk fibroin molecules are small enough to penetrate the gaps between the hair cuticles, forming a relatively uniform and thick protective film on the hair surface. It is evident that adding an appropriate concentration of silk fibroin plays a beneficial role both on the hair surface and within the hair shaft, not only making the hair surface smoother and reducing resistance during combing, but also enhancing the overall strength of the hair, making it less prone to breakage and static electricity during combing, thus resulting in smoother combing and a significant reduction in combing resistance.

[0118] (2) Tensile strength of hair

[0119] Tensile strength tests were performed on hair strands before and after using the shampoo from Example 1 and Comparative Example 1, respectively. The results are as follows: Figure 2 The results show that, compared to Comparative Example 1, the hair strands treated with the shampoo of Example 1 exhibit significantly enhanced tensile strength, demonstrating a stronger stretching effect. This is because: on the one hand, the silk fibroin penetrating the hair shaft binds to keratin, enhancing the cohesion of the hair fibers and enabling the hair to withstand greater tensile force; on the other hand, the protective film on the surface also plays a role in evenly distributing the tensile force, preventing excessive local stress on the hair strands and thus preventing breakage. Therefore, at this concentration of added silk fibroin, the hair can withstand greater tensile force, and the tensile strength is significantly improved.

[0120] (3) Gloss

[0121] The shine of hair before and after using the shampoo of Example 1 and Comparative Example 1 was tested. The results are as follows: Figure 3 The results show that, compared to Comparative Example 1, hair treated with the shampoo of Example 1 exhibits significantly improved shine, displaying a bright and natural luster, and visually, better hair texture. This is because silk fibroin can fully penetrate the hair shaft, interacting with keratin to enhance hair stability; simultaneously, the serine, tyrosine, and other amino acids in its composition can improve the hair's refraction and reflection of light. Therefore, the concentration of silk fibroin added in Example 1 demonstrates excellent results.

[0122] (4) Inhibition rate against Malassezia

[0123] By comparing the antibacterial experiments of Example 1 (containing optimized concentration of silk fibroin hydrolysate / tourmaline / persimmon tannin extract) with Comparative Example 2 (high concentration of persimmon extract) and Comparative Example 3 (low concentration of tourmaline), and referring to... Figure 4 The study found that the three-component synergistic system in Example 1 significantly improved the inhibitory efficiency against Malassezia. Within a 48-hour culture period, Example 1 achieved a 95% inhibition rate against Malassezia, significantly higher than the 87% in Comparative Example 2 and 84% in Comparative Example 3. This is because, in Comparative Example 2, although the high concentration of persimmon extract exhibited antibacterial activity due to the antibacterial properties of tannins, the excessively high concentration led to the aggregation of tannin molecules, reducing the effective contact area with Malassezia and thus lowering the antibacterial efficiency. In Comparative Example 3, due to insufficient nano-tourmaline content, the intensity of the micro-electric field generated by its spontaneous surface polarization was reduced, failing to effectively drive electron transfer in the silk fibroin-tannin complex. Specifically, although tannins can specifically bind to β-1,3-glucan in the Malassezia cell wall through multi-point hydrogen bonds, blocking nutrient penetration, the insufficient micro-electric field intensity of tourmaline resulted in a decreased regeneration rate of the quinone structure after tannin oxidation, ultimately limiting the antibacterial efficiency.

[0124] In summary, this invention, based on the synergistic effect of silk fibroin, tourmaline powder, and persimmon extract, achieves multi-dimensional and long-term control of "old people's smell" through physical antibacterial barrier blocking contact, negative ion targeted decomposition of odor, and tannin-based antioxidant effect. At the same time, it avoids the risks of drug resistance, irritation, and microecological damage of traditional technologies, providing a safer, more stable, and more adaptable odor removal solution for the elderly.

[0125] The present invention has been described in detail above with reference to specific embodiments and exemplary examples; however, these descriptions should not be construed as limiting the present invention. Those skilled in the art will understand that various equivalent substitutions, modifications, or improvements can be made to the technical solutions and embodiments of the present invention without departing from the spirit and scope of the invention, and all such modifications and improvements fall within the scope of the present invention. The scope of protection of the present invention is defined by the appended claims.

Claims

1. A method for preparing a long-lasting deodorizing shampoo, characterized in that, Includes the following steps: S1. Dissolve pure water and EDTA-2Na in a mixture, heat to 60-90℃, add K12A and cocamidopropyl betaine, and stir to mix. S2. Allow to cool naturally to 20-50℃, then add nano tourmaline powder, silk fibroin hydrolysate, persimmon tannin extract, D-panthenol, glycerin, polyquaternium-10, Kathon and sodium chloride, and stir to mix. S3. Adjust the pH to 4.5-7.0, continue stirring, and obtain the long-lasting deodorizing shampoo.

2. The method for preparing the long-lasting deodorizing shampoo as described in claim 1, characterized in that, The shampoo comprises the following ingredients by weight percentage: EDTA-2Na: 0.05%~0.5%; K12A: 1-10%; Cocamidopropyl betaine: 3%–8%; Nano tourmaline powder: 0.5%–3%; Silk fibroin hydrolysate: 1%–5%; Persimmon tannin extract: 0.5%–2.5%; D-Panthenol: 0.1%–1%; Glycerin: 2%–5%; Polyquaternium-10: 0.5%–1.5%; Kathon: 0.1–0.5%; Sodium chloride: 0.5–3%; The remainder consists of pH adjuster and water.

3. The method for preparing the long-lasting deodorizing shampoo as described in claim 1, characterized in that, The molecular weight of the silk fibroin hydrolysate is ≤10kDa.

4. The method for preparing the long-lasting deodorizing shampoo as described in claim 1, characterized in that, In S3, the pH is adjusted using citrate buffer.

5. The method for preparing the long-lasting deodorizing shampoo as described in claim 1, characterized in that, In S3, the stirring time is 10-30 minutes.

6. The method for preparing the long-lasting deodorizing shampoo as described in claim 1, characterized in that, The preparation method of the silk fibroin hydrolysate is as follows: (1) Place the silk in a sodium carbonate aqueous solution, treat it at 70-100℃, and then wash and dry it; (2) The dried silk is crushed and distilled water is added and stirred to obtain a suspension; (3) Adjust the pH of the suspension to 8-9 and heat it to 45-55℃; (4) Add trypsin, stir and react, then sterilize and filter to obtain silk fibroin hydrolysate.

7. The method for preparing the long-lasting deodorizing shampoo as described in claim 6, characterized in that, In step (2), the amount of silk added to the suspension is 2wt%-10wt%, the stirring speed is 150-200r / min, and the time is 10-15min.

8. The method for preparing the long-lasting deodorizing shampoo as described in claim 6, characterized in that, In step (4), the amount of trypsin added is 1%-5% of the weight of the silk, and the stirring speed is 100-200 r / min.

9. The method for preparing the long-lasting deodorizing shampoo as described in claim 6, characterized in that, In step (4), the sterilization temperature is 90-100℃ and the time is 10-15min.

10. A long-lasting deodorizing shampoo prepared by the preparation method according to any one of claims 1-9.

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