Stomach-invigorating and qi-guiding pill as well as preparation method and application thereof

Abstract

The invention provides a stomach invigorating and qi guiding pill, a preparation method and application thereof, and relates to the field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 12 to 15 parts of flos caryophylli, 12 to 15 parts of rhizoma cyperi, 12 to 15 parts of fructus aurantii immaturus, 12 to 15 parts of cortex magnoliae officinalis, 25 to 30 parts of pericarpium trichosanthis, 12 to 15 parts of radix linderae, 6 to 9 parts of rhizoma zingiberis, 12 to 15 parts of cortex cinnamomi, 9 to 12 parts of radix paeoniae alba, 25 to 30 parts of radix astragali seu hedysari, 25 to 30 parts of radix pseudostellariae and 9 to 12 parts of radix bupleuri. The stomach-invigorating and qi-guiding pill is used for treating deficiency-cold in spleen and stomach, deficiency of qi and blood and intermingled phlegm and blood stasis, and has the effects of tonifying spleen with fragrance, relaxing bowels, promoting the circulation of qi, tonifying spleen, replenishing qi and harmonizing stomach, and reducing phlegm with sweet and warm taste. The pill is fixed on the Zhongwan acupoint, the Shenque acupoint, the Tianshu acupoint and the Zusanli acupoint through application, and stomach diseases caused by malignant tumors can be effectively treated.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine, and more specifically, to a stomach-strengthening and qi-regulating pill, its preparation method, and its application. Background Technology

[0002] Gastroparesis is a clinical syndrome centered on gastric motility disorder, which Traditional Chinese Medicine (TCM) categorizes as "stomach fullness" or "abdominal distension." Spleen and stomach deficiency-cold, qi stagnation and phlegm obstruction are common TCM syndrome types of gastroparesis. Its pathogenesis is complex, and treatment requires a comprehensive approach, encompassing warming the middle jiao and dispelling cold, regulating qi and resolving phlegm, and strengthening the spleen and stomach. The spleen and stomach are the foundation of acquired constitution and the source of qi and blood production. Improper diet, overexertion, or prolonged illness can damage the spleen, leading to spleen yang deficiency and impaired warming function, resulting in symptoms of coldness and coldness such as epigastric pain, preference for warmth and pressure, poor appetite, and loose stools. Modern research confirms that patients with spleen and stomach deficiency-cold syndrome experience reduced gastric mucosal blood flow and decreased digestive enzyme activity, which are related to the pathological mechanism of gastric motility disorder. Spleen deficiency leads to impaired transportation and transformation, resulting in internal retention of dampness, which accumulates into phlegm. Phlegm and dampness obstruct qi flow, further aggravating symptoms such as epigastric distension, belching, and hiccups. Qi stagnation and phlegm obstruction are mutually causal, forming a vicious cycle. Studies have shown that gastric electrical rhythm disorders and delayed gastric emptying in patients with gastroparesis due to qi stagnation and phlegm obstruction are closely related to autonomic nervous system dysfunction.

[0003] Currently, there are many medications on the market for treating gastroparesis caused by spleen and stomach deficiency and cold, qi stagnation and phlegm obstruction. These medications primarily work by warming the middle jiao (spleen and stomach), promoting qi circulation, and resolving phlegm and stagnation, and are mainly taken orally. Patients with spleen and stomach deficiency, qi and blood insufficiency, and phlegm and blood stasis caused by tumors or medications are often in a state of fasting or unable to eat, therefore, oral medications cannot be taken normally. Furthermore, injectable preparations and acupoint patch preparations of this type of medication on the market that do not require oral administration are less effective or have fewer varieties. Summary of the Invention

[0004] The purpose of this invention is to provide a stomach-strengthening and qi-regulating pill for treating spleen and stomach deficiency, qi and blood deficiency, and phlegm and blood stasis. This stomach-strengthening and qi-regulating pill has the effects of aromatic spleen-strengthening, bowel-regulating and qi-regulating, spleen-strengthening and qi-boosting, stomach-soothing, sweet and warm phlegm-resolving.

[0005] Another objective of this invention is to provide a method for preparing Jianwei Shunqi Pills, which is simple to prepare and requires minimal equipment.

[0006] The third objective of this invention is to provide an application of Jianwei Shunqi Pill, which is combined with a poultice to form an external patch. The patch can be applied and fixed to the Zhongwan, Shenque, Tianshu, and Zusanli acupoints, and it has excellent therapeutic effects on stomach diseases.

[0007] The technical problem solved by this invention is achieved by the following technical solution.

[0008] On one hand, embodiments of the present invention provide a stomach-strengthening and qi-regulating pill, which, by weight, comprises the following ingredients:

[0009] Clove 12-15 parts, Cyperus rotundus 12-15 parts, Citrus aurantium 12-15 parts, Magnolia officinalis 12-15 parts, Trichosanthes kirilowii peel 25-30 parts, Lindera strychnifolia 12-15 parts, dried ginger 6-9 parts, cinnamon 12-15 parts, white peony root 9-12 parts, Astragalus membranaceus 25-30 parts, Pseudostellaria heterophylla 25-30 parts, Bupleurum chinense 9-12 parts.

[0010] In some embodiments of the present invention, the raw materials include the following by weight:

[0011] 15 parts cloves, 15 parts cyperus rhizome, 15 parts immature bitter orange, 15 parts magnolia bark, 30 parts trichosanthes peel, 15 parts lindera root, 9 parts dried ginger, 15 parts cinnamon, 12 parts white peony root, 30 parts astragalus root, 30 parts codonopsis root, and 12 parts bupleurum root.

[0012] In some embodiments of the present invention, the raw materials include the following by weight:

[0013] 12 parts cloves, 12 parts cyperus rhizome, 12 parts immature bitter orange, 12 parts magnolia bark, 25 parts trichosanthes peel, 12 parts lindera root, 6 parts dried ginger, 12 parts cinnamon, 9 parts white peony root, 25 parts astragalus root, 25 parts codonopsis root, and 9 parts bupleurum root.

[0014] In some embodiments of the present invention, the raw materials include the following by weight:

[0015] Clove 13.5 parts, Cyperus rotundus 13.5 parts, Citrus aurantium 13.5 parts, Magnolia officinalis 13.5 parts, Trichosanthes kirilowii peel 27 parts, Lindera strychnifolia 13.5 parts, Zingiber officinale 7.5 parts, Cinnamomum cassia 13.5 parts, Paeonia lactiflora 10 parts, Astragalus membranaceus 27 parts, Codonopsis pilosula 27 parts, Bupleurum chinense 10 parts.

[0016] On the other hand, embodiments of the present invention provide a method for preparing a stomach-strengthening and qi-regulating pill, comprising the following steps:

[0017] S1. Clean each raw material thoroughly, dry it, and grind it into powder.

[0018] S2. Mix the powders of each ingredient evenly, add rice wine and petroleum jelly, mix evenly, and then make into pills to obtain the Jianwei Shunqi Pills.

[0019] In some embodiments of the present invention, in step S1, the particle size of the powder is 100-200 μm.

[0020] In some embodiments of the present invention, in step S2, the ratio of the total mass of each raw material powder, the mass of rice wine, and the mass of petroleum jelly is (1-1.5):(0.5-1):(0.5-1).

[0021] In some embodiments of the present invention, the ratio of the total mass of the raw material powders, the mass of rice wine, and the mass of petroleum jelly is 1:0.5:0.5.

[0022] Thirdly, this invention provides an application of Jianwei Shunqi Pill in the preparation of a drug for treating stomach diseases, wherein the Jianwei Shunqi Pill is attached to a patch to prepare a topical patch.

[0023] Compared with the prior art, the embodiments of the present invention have at least the following advantages or beneficial effects:

[0024] The present invention provides a stomach-strengthening and qi-regulating pill, which is designed for gastroparesis caused by spleen and stomach deficiency and cold, qi stagnation and phlegm obstruction, and uses the method of warming the middle jiao, promoting qi circulation, resolving phlegm and unblocking stagnation.

[0025] The principal herbs are cloves, which are pungent and warm, primarily entering the spleen and stomach. They warm the middle burner, relieve nausea and vomiting, dispel cold and relieve pain, directly addressing the root cause of gastric paralysis and deficiency-cold. Cyperus rotundus is pungent and neutral, soothing the liver, relieving depression, regulating qi, and relieving chest congestion, targeting the symptoms of liver qi stagnation affecting the stomach and qi stagnation. Together, they warm and disperse cold stagnation in the middle burner and relieve qi stagnation, serving as the principal herbs.

[0026] The assistant herbs: Fructus Aurantii Immaturus (Zhi Shi) is bitter and descending, breaking up stagnation and eliminating accumulation; Cortex Magnoliae Officinalis (Houpu) is bitter and warm, drying dampness and relieving fullness. Together, they specifically target stagnation and fullness in the middle jiao (middle burner), assisting the principal herb in clearing gastrointestinal stagnation. Radix Linderae (Wu Yao) promotes qi circulation and relieves pain, while also addressing stagnation and cold congealing in the lower jiao, preventing stomach and intestinal problems. Radix Astragali (Huang Qi) and Radix Codonopsis pilosula (Tai Zi Shen) are sweet and warm, tonifying qi, strengthening the spleen and stomach, and preventing qi-regulating herbs from depleting vital energy, embodying the principle of "tonifying the middle while promoting circulation." Pericarpium Trichosanthis (Gua Lou Pi) widens the chest, clears phlegm, disperses nodules, and unblocks the meridians, resolving phlegm and blood stasis caused by prolonged qi stagnation, targeting the concurrent symptoms of phlegm and dampness obstructing the middle jiao in gastroparesis.

[0027] The adjuvant herbs: Dried ginger, which is stabilizing and warming the Yang of the middle Jiao; and cinnamon, which guides the fire back to its source and unblocks the fire of the Mingmen (Gate of Life). These two herbs assist the principal herb in enhancing its warming and dispersing effects, targeting the core pathogenesis of gastric paralysis due to deficiency and cold. White peony root, being sour and cold, nourishes Yin, softens the liver, relieves spasms, and nourishes blood and regulates the Ying, preventing the pungent and drying herbs from damaging Yin and relieving stomach cramps.

[0028] The guiding herbs: Bupleurum, being light and dispersing, soothes the liver, relieves stagnation, and raises clear yang. Combined with Cyperus, it regulates the qi of the liver and stomach, aligning with the principle of "treating the stomach requires regulating the liver." Bupleurum also guides the other herbs into the liver and gallbladder meridians, regulating qi. The entire formula follows the principle of "warming what is cold and promoting circulation what is stagnant," with clear layers of combination, combining warming and unblocking, attacking and tonifying, regulating both the liver and stomach, and treating both phlegm and qi stagnation. Attached Figure Description

[0029] To more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of the present invention and should not be regarded as a limitation on the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0030] Figure 1 Statistics on treatment cases of the drugs in the embodiments of the present invention Figure 1 ;

[0031] Figure 2Statistics on treatment cases of the drugs in the embodiments of the present invention Figure 2 . Detailed Implementation

[0032] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. Where specific conditions are not specified in the embodiments, conventional conditions or conditions recommended by the manufacturer shall apply. Reagents or instruments whose manufacturers are not specified are all conventional products that can be purchased commercially.

[0033] It should be noted that, unless otherwise specified, the embodiments and features described in the present invention can be combined with each other. The present invention will now be described in detail with reference to specific embodiments.

[0034] On one hand, embodiments of the present invention provide a stomach-strengthening and qi-regulating pill, which, by weight, comprises the following ingredients:

[0035] Clove 12-15 parts, Cyperus rotundus 12-15 parts, Citrus aurantium 12-15 parts, Magnolia officinalis 12-15 parts, Trichosanthes kirilowii peel 25-30 parts, Lindera strychnifolia 12-15 parts, dried ginger 6-9 parts, cinnamon 12-15 parts, white peony root 9-12 parts, Astragalus membranaceus 25-30 parts, Pseudostellaria heterophylla 25-30 parts, Bupleurum chinense 9-12 parts.

[0036] Preferably, the stomach-strengthening and qi-regulating pills comprise the following ingredients by weight:

[0037] 15 parts cloves, 15 parts cyperus rhizome, 15 parts immature bitter orange, 15 parts magnolia bark, 30 parts trichosanthes peel, 15 parts lindera root, 9 parts dried ginger, 15 parts cinnamon, 12 parts white peony root, 30 parts astragalus root, 30 parts codonopsis root, and 12 parts bupleurum root.

[0038] Preferably, the stomach-strengthening and qi-regulating pills comprise the following ingredients by weight:

[0039] 12 parts cloves, 12 parts cyperus rhizome, 12 parts immature bitter orange, 12 parts magnolia bark, 25 parts trichosanthes peel, 12 parts lindera root, 6 parts dried ginger, 12 parts cinnamon, 9 parts white peony root, 25 parts astragalus root, 25 parts codonopsis root, and 9 parts bupleurum root.

[0040] Preferably, the stomach-strengthening and qi-regulating pills comprise the following ingredients by weight:

[0041] Clove 13.5 parts, Cyperus rotundus 13.5 parts, Citrus aurantium 13.5 parts, Magnolia officinalis 13.5 parts, Trichosanthes kirilowii peel 27 parts, Lindera strychnifolia 13.5 parts, Zingiber officinale 7.5 parts, Cinnamomum cassia 13.5 parts, Paeonia lactiflora 10 parts, Astragalus membranaceus 27 parts, Codonopsis pilosula 27 parts, Bupleurum chinense 10 parts.

[0042] Clove, properties of the medicine: pungent, warm. It acts on the spleen, stomach, and kidney meridians. Functions: warming the middle-jiao to lower adverse qi, tonifying the kidney to boost yang. Indications: hiccups and vomiting caused by deficiency-cold of the spleen and stomach, anorexia and vomiting and diarrhea; impotence, cold uterus, and cold pain in the waist and knees caused by decline of kidney-yang. It contains volatile oil components, has antibacterial, antiviral, and digestive functions, and can inhibit the formation of gastric ulcers.

[0043] Cyperus rotundus, properties of the medicine: pungent, slightly bitter, slightly sweet, flat. It acts on the liver, spleen, and triple energizer meridians. Functions: soothing the liver and relieving depression, regulating qi to ease the middle-jiao, regulating menstruation and alleviating pain. Indications: distending pain in the chest and hypochondrium caused by stagnation of liver qi, irregular menstruation, dysmenorrhea; distending pain in the epigastrium and abdomen caused by qi stagnation of the spleen and stomach. It contains cyperol, has analgesic, anti-inflammatory, and uterine contraction-regulating functions, and can lower blood pressure and antidepressant.

[0044] Immature bitter orange, properties of the medicine: bitter, pungent, sour, slightly cold. It acts on the spleen and stomach meridians. Functions: breaking qi to eliminate stagnation, resolving phlegm and dispersing masses. Indications: food retention with qi stagnation, distending pain in the epigastrium and abdomen; chest impediment and knotted chest caused by phlegm turbidity obstruction; visceral ptosis. It regulates gastrointestinal motility, enhances myocardial contractility, and inhibits platelet aggregation.

[0045] Magnolia officinalis, properties of the medicine: bitter, pungent, warm. It acts on the spleen, stomach, lung, and large intestine meridians. Functions: drying dampness and resolving phlegm, lowering qi to relieve fullness. Indications: dampness stagnating in the middle-jiao, stuffiness and vomiting and diarrhea in the epigastrium; food retention with qi stagnation, abdominal distension and constipation; cough and dyspnea due to fluid-retention phlegm. It has anti-ulcer, gastrointestinal motility-regulating, and bronchial smooth muscle-relaxing effects.

[0046] Snakegourd pericarp, properties of the medicine: sweet, cold. It acts on the lung and stomach meridians. Functions: clearing heat and resolving phlegm, promoting qi flow and widening the chest. Indications: cough with phlegm-heat, chest distress and pain in the hypochondrium; chest impediment and knotted chest. It has antitussive, expectorant, anti-myocardial ischemia, and coronary artery-dilating effects.

[0047] Lindera aggregata, properties of the medicine: pungent, warm. It acts on the lung, spleen, kidney, and bladder meridians. Functions: promoting qi flow to relieve pain, warming the kidney and dispelling cold. Indications: distending pain in the chest and abdomen caused by cold coagulation and qi stagnation; dysmenorrhea, frequent urination and enuresis; asthma, cough. Modern research: anti-inflammatory, analgesic, promoting gastrointestinal peristalsis, protecting the liver.

[0048] Dry ginger, properties of the medicine: pungent, hot. It acts on the spleen, stomach, kidney, heart, and lung meridians. Functions: warming the middle-jiao to dispel cold, restoring yang and unblocking meridians, warming the lung to resolve fluid-retention. Indications: cold pain in the epigastrium and abdomen, vomiting and diarrhea caused by deficiency-cold of the spleen and stomach; cold limbs and feeble pulse due to deficiency of heart and kidney yang; cough and dyspnea due to cold fluid-retention. It has antibacterial, anti-inflammatory, improving cardiovascular function, and preventing thrombosis formation effects.

[0049] Cinnamon, properties of the medicine: pungent, sweet, very hot. It acts on the kidney, spleen, heart, and liver meridians. Functions: tonifying fire and boosting yang, dispersing cold and alleviating pain, warming and unblocking meridians. Indications: impotence, cold uterus, cold pain in the waist and knees due to insufficient kidney yang; dysmenorrhea, amenorrhea due to cold congealing and blood stasis; deficiency-cold vomiting and diarrhea. It has blood vessel-dilating, anti-platelet aggregation, blood sugar-lowering, and sedative and analgesic effects.

[0050] White peony root, medicinal properties: bitter, sour, slightly cold. It enters the liver and spleen meridians. Functions: nourishes blood and regulates menstruation, astringes yin and stops sweating, softens the liver and relieves pain, calms liver yang. Indications: blood deficiency and chlorosis, irregular menstruation; spontaneous sweating and night sweats; hypochondriac pain and abdominal pain due to liver stagnation; headache and dizziness due to liver yang hyperactivity. It also has analgesic, anti-inflammatory, immune-regulating, liver-protecting, and anti-thrombotic effects.

[0051] Astragalus, medicinal properties: sweet, slightly warm. Enters the lung and spleen meridians. Functions: tonifies qi and raises yang, strengthens the exterior and stops sweating, promotes diuresis and reduces swelling, and promotes pus drainage and detoxification. Indications: qi deficiency and fatigue, poor appetite and loose stools; spontaneous sweating due to exterior deficiency; edema and difficulty urinating; chronic sores that fail to ulcerate. Enhances immunity, regulates blood sugar, has antioxidant properties, and combats fatigue.

[0052] Codonopsis pilosula, medicinal properties: sweet, slightly bitter, neutral. It enters the spleen and lung meridians. Functions: tonifies qi and strengthens the spleen, generates fluids and moistens the lungs. Indications: fatigue and loss of appetite due to spleen deficiency; spontaneous sweating and thirst due to qi and yin deficiency; dry cough due to lung dryness. It also has anti-fatigue, antioxidant, immune-regulating, and cardiac function-improving effects.

[0053] Bupleurum (Chai Hu) has the following medicinal properties: bitter, pungent, and slightly cold. It enters the liver, gallbladder, and lung meridians. Its functions include dispersing and reducing fever, soothing the liver and relieving stagnation, and raising yang qi. It is indicated for: fever due to colds, alternating chills and fever; chest and rib pain due to liver qi stagnation; uterine prolapse and rectal prolapse due to qi deficiency. It also has antipyretic, anti-inflammatory, liver-protective, antidepressant, and immune-regulating effects.

[0054] On the other hand, embodiments of the present invention provide a method for preparing a stomach-strengthening and qi-regulating pill, comprising the following steps:

[0055] S1. Clean each raw material thoroughly, dry it, and grind it into powder with a particle size of 100-200um.

[0056] S2, mix the powders of each raw material evenly, add rice wine and petroleum jelly, mix evenly, and then make into pills to obtain the stomach-strengthening and qi-regulating pills. The ratio of the total mass of the raw material powders, the mass of rice wine and the mass of petroleum jelly is (1-1.5):(0.5-1):(0.5-1), and more preferably, this ratio is 1:0.5:0.5.

[0057] Thirdly, this invention provides an application of Jianwei Shunqi Pill in the preparation of medicines for treating stomach diseases. The Jianwei Shunqi Pill is attached to a dressing to prepare a topical patch. This patch can be made fresh to order, using medical gauze or a dressing as a carrier, with the pill attached to the carrier. Alternatively, the pill can be fixed to a medical dressing and then aseptically packaged. When using, the packaging is torn open and the patch is applied to the corresponding acupoint.

[0058] Instructions for use: Apply the patch to the Zhongwan, Shenque, Tianshu, and Zusanli acupoints and remove it after 6 hours. It is used to treat stomach diseases, especially stomach diseases caused by malignant tumors, such as stomach bloating, pain, and discomfort caused by maintenance chemotherapy for malignant tumors.

[0059] The features and performance of the present invention will be further described in detail below with reference to embodiments.

[0060] Example 1

[0061] Prepare the raw materials according to the following proportions:

[0062] 15 parts cloves, 15 parts cyperus rhizome, 15 parts immature bitter orange, 15 parts magnolia bark, 30 parts trichosanthes peel, 15 parts lindera root, 9 parts dried ginger, 15 parts cinnamon, 12 parts white peony root, 30 parts astragalus root, 30 parts codonopsis root, and 12 parts bupleurum root.

[0063] Based on this formula, the Jianwei Shunqi Pill of this embodiment was prepared as follows:

[0064] S1. Clean each raw material thoroughly, dry it, grind it into powder, sieve it, and select powder with an average particle size of 100±10um for later use.

[0065] S2. Mix the powdered ingredients evenly, add rice wine and petroleum jelly, mix evenly, and then form into pills to obtain the Jianwei Shunqi Pill. The ratio of the total mass of the powdered ingredients, the mass of the rice wine, and the mass of the petroleum jelly is 1:0.5:0.5.

[0066] Instructions for use: Press the prepared pills onto a gauze patch and fix them to the patient's Zhongwan, Shenque, Tianshu, and Zusanli acupoints. Remove the patch after 6 hours.

[0067] Example 2

[0068] Prepare the raw materials according to the following proportions:

[0069] 12 parts cloves, 12 parts cyperus rhizome, 12 parts immature bitter orange, 12 parts magnolia bark, 25 parts trichosanthes peel, 12 parts lindera root, 6 parts dried ginger, 12 parts cinnamon, 9 parts white peony root, 25 parts astragalus root, 25 parts codonopsis root, and 9 parts bupleurum root.

[0070] Based on this formula, the Jianwei Shunqi Pill of this embodiment was prepared as follows:

[0071] S1. Clean each raw material thoroughly, dry it, grind it into powder, sieve it, and select powder with an average particle size of 100±10um for later use.

[0072] S2. Mix the powdered ingredients evenly, add rice wine and petroleum jelly, mix evenly, and then form into pills to obtain the Jianwei Shunqi Pill. The ratio of the total mass of the powdered ingredients, the mass of the rice wine, and the mass of the petroleum jelly is 1:0.5:0.5.

[0073] Instructions for use: Press the prepared pills onto a gauze patch and fix them to the patient's Zhongwan, Shenque, Tianshu, and Zusanli acupoints. Remove the patch after 6 hours.

[0074] Example 3

[0075] Prepare the raw materials according to the following proportions:

[0076] Clove 13.5 parts, Cyperus rotundus 13.5 parts, Citrus aurantium 13.5 parts, Magnolia officinalis 13.5 parts, Trichosanthes kirilowii peel 27 parts, Lindera strychnifolia 13.5 parts, Zingiber officinale 7.5 parts, Cinnamomum cassia 13.5 parts, Paeonia lactiflora 10 parts, Astragalus membranaceus 27 parts, Codonopsis pilosula 27 parts, Bupleurum chinense 10 parts.

[0077] Based on this formula, the Jianwei Shunqi Pill of this embodiment was prepared as follows:

[0078] S1. Clean each raw material thoroughly, dry it, grind it into powder, sieve it, and select powder with an average particle size of 100±10um for later use.

[0079] S2. Mix the powdered ingredients evenly, add rice wine and petroleum jelly, mix evenly, and then form into pills to obtain the Jianwei Shunqi Pill. The ratio of the total mass of the powdered ingredients, the mass of the rice wine, and the mass of the petroleum jelly is 1:0.5:0.5.

[0080] Instructions for use: Press the prepared pills onto a gauze patch and fix them to the patient's Zhongwan, Shenque, Tianshu, and Zusanli acupoints. Remove the patch after 6 hours.

[0081] Typical Cases

[0082] 1. Ms. Ge, 61 years old, hospital number: 00235673, diagnosis: maintenance chemotherapy for malignant tumor, experiencing abdominal distension and pain, vomiting twice, the contents of the stomach, about 5ml each time, no flatus for 2 days, significant abdominal distension, tympanic sound on percussion. After applying Jianwei Shunqi Pills to acupoints, the vomiting was controlled, flatus was restored, one bowel movement was performed, and the symptoms disappeared.

[0083] 2. Li Moufu, male, 65 years old, hospital number: 00235769, diagnosis: targeted therapy for end-stage malignant tumor, felt discomfort in the epigastric region, vomited 5 times, the vomit consisted of gastric contents, each time about 10ml, after applying Jianwei Shunqi Pills to acupoints, the vomiting was controlled and the symptoms disappeared, and the laboratory tests were normal.

[0084] 3. Xu Mouhua, male, 48 years old, hospital number: 00243669, diagnosis: maintenance chemotherapy for malignant tumor, feeling discomfort in the epigastric region, feeling nauseous and vomiting, vomiting 3 times, vomiting gastric contents, small amount, after applying Jianwei Shunqi Pill to acupoints, the nausea and vomiting were controlled and the symptoms of nausea and vomiting disappeared.

[0085] In summary, the stomach-strengthening and qi-regulating pill provided by this embodiment of the invention is designed for gastroparesis caused by spleen and stomach deficiency and cold, qi stagnation and phlegm obstruction, and its method is to warm the middle jiao, promote qi circulation, resolve phlegm and unblock stagnation.

[0086] The principal herbs are cloves, which are pungent and warm, primarily entering the spleen and stomach. They warm the middle burner, relieve nausea and vomiting, dispel cold and relieve pain, directly addressing the root cause of gastric paralysis and deficiency-cold. Cyperus rotundus is pungent and neutral, soothing the liver, relieving depression, regulating qi, and relieving chest congestion, targeting the symptoms of liver qi stagnation affecting the stomach and qi stagnation. Together, they warm and disperse cold stagnation in the middle burner and relieve qi stagnation, serving as the principal herbs.

[0087] The assistant herbs: Fructus Aurantii Immaturus (Zhi Shi) is bitter and descending, breaking up stagnation and eliminating accumulation; Cortex Magnoliae Officinalis (Houpu) is bitter and warm, drying dampness and relieving fullness. Together, they specifically target stagnation and fullness in the middle jiao (middle burner), assisting the principal herb in clearing gastrointestinal stagnation. Radix Linderae (Wu Yao) promotes qi circulation and relieves pain, while also addressing stagnation and cold congealing in the lower jiao, preventing stomach and intestinal problems. Radix Astragali (Huang Qi) and Radix Codonopsis pilosula (Tai Zi Shen) are sweet and warm, tonifying qi, strengthening the spleen and stomach, and preventing qi-regulating herbs from depleting vital energy, embodying the principle of "tonifying the middle while promoting circulation." Pericarpium Trichosanthis (Gua Lou Pi) widens the chest, clears phlegm, disperses nodules, and unblocks the meridians, resolving phlegm and blood stasis caused by prolonged qi stagnation, targeting the concurrent symptoms of phlegm and dampness obstructing the middle jiao in gastroparesis.

[0088] The adjuvant herbs: Dried ginger, which is stabilizing and warming the Yang of the middle Jiao; and cinnamon, which guides the fire back to its source and unblocks the fire of the Mingmen (Gate of Life). These two herbs assist the principal herb in enhancing its warming and dispersing effects, targeting the core pathogenesis of gastric paralysis due to deficiency and cold. White peony root, being sour and cold, nourishes Yin, softens the liver, relieves spasms, and nourishes blood and regulates the Ying, preventing the pungent and drying herbs from damaging Yin and relieving stomach cramps.

[0089] The guiding herbs: Bupleurum, being light and dispersing, soothes the liver, relieves stagnation, and raises clear yang. Combined with Cyperus, it regulates the qi of the liver and stomach, aligning with the principle of "treating the stomach requires regulating the liver." Bupleurum also guides the other herbs into the liver and gallbladder meridians, regulating qi. The entire formula follows the principle of "warming what is cold and promoting circulation what is stagnant," with clear layers of combination, combining warming and unblocking, attacking and tonifying, regulating both the liver and stomach, and treating both phlegm and qi stagnation.

[0090] The embodiments described above are some, but not all, embodiments of the present invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

Claims

1. A stomach-strengthening and qi-regulating pill, characterized in that, By weight, it includes the following ingredients: Clove 12-15 parts, Cyperus rotundus 12-15 parts, Citrus aurantium 12-15 parts, Magnolia officinalis 12-15 parts, Trichosanthes kirilowii peel 25-30 parts, Lindera strychnifolia 12-15 parts, dried ginger 6-9 parts, cinnamon 12-15 parts, white peony root 9-12 parts, Astragalus membranaceus 25-30 parts, Pseudostellaria heterophylla 25-30 parts, Bupleurum chinense 9-12 parts.

2. The stomach-strengthening and qi-regulating pill according to claim 1, characterized in that, By weight, it includes the following ingredients: 15 parts cloves, 15 parts cyperus rhizome, 15 parts immature bitter orange, 15 parts magnolia bark, 30 parts trichosanthes peel, 15 parts lindera root, 9 parts dried ginger, 15 parts cinnamon, 12 parts white peony root, 30 parts astragalus root, 30 parts codonopsis root, and 12 parts bupleurum root.

3. The stomach-strengthening and qi-regulating pill according to claim 1, characterized in that, By weight, it includes the following ingredients: 12 parts cloves, 12 parts cyperus rhizome, 12 parts immature bitter orange, 12 parts magnolia bark, 25 parts trichosanthes peel, 12 parts lindera root, 6 parts dried ginger, 12 parts cinnamon, 9 parts white peony root, 25 parts astragalus root, 25 parts codonopsis root, and 9 parts bupleurum root.

4. The stomach-strengthening and qi-regulating pill according to claim 1, characterized in that, By weight, it includes the following ingredients: Clove 13.5 parts, Cyperus rotundus 13.5 parts, Citrus aurantium 13.5 parts, Magnolia officinalis 13.5 parts, Trichosanthes kirilowii peel 27 parts, Lindera strychnifolia 13.5 parts, Zingiber officinale 7.5 parts, Cinnamomum cassia 13.5 parts, Paeonia lactiflora 10 parts, Astragalus membranaceus 27 parts, Codonopsis pilosula 27 parts, Bupleurum chinense 10 parts.

5. A method for preparing the Jianwei Shunqi Pill as described in any one of claims 1-4, characterized in that, Includes the following steps: S1. Clean each raw material thoroughly, dry it, and grind it into powder. S2. Mix the powders of each ingredient evenly, add rice wine and petroleum jelly, mix evenly, and then make into pills to obtain the Jianwei Shunqi Pills.

6. The method for preparing the Jianwei Shunqi Pill according to claim 5, characterized in that, In step S1, the particle size of the powder is 100-200 μm.

7. The method for preparing the Jianwei Shunqi Pill according to claim 5, characterized in that, In step S2, the ratio of the total mass of each raw material powder, the mass of rice wine, and the mass of petroleum jelly is (1-1.5):(0.5-1):(0.5-1).

8. The method for preparing the Jianwei Shunqi Pill according to claim 5, characterized in that, The ratio of the total mass of the raw material powders, the mass of the rice wine, and the mass of the petroleum jelly is 1:0.5:0.

5.

9. The use of the Jianwei Shunqi Pill as described in any one of claims 1-4 in the preparation of a medicament for treating stomach diseases, characterized in that, The stomach-strengthening and qi-regulating pills are attached to a patch to prepare a topical patch.

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