A bistable suction cup device for enhancing the performance of microneedles and a method of manufacturing the same

By designing a bistable suction cup device, the negative pressure adsorption is generated by the "outward-rebound" mechanism of the elastic hemispherical shell, which solves the problems of poor fixation of microneedle systems, low drug delivery efficiency, and small amount of interstitial fluid collection. This achieves more efficient drug delivery and interstitial fluid collection, simplifies operation, and reduces costs.

CN121102708BActive Publication Date: 2026-09-11HANGZHOU INSTITUTE OF MEDICAL SCIENCES CHINESE ACADEMY OF SCIENCES
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Patent Information

Application Number
CN202511227357.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-08-29
Publication Date
2026-09-11
Estimated Expiration
2045-08-29

AI Technical Summary

Technical Problem

Existing microneedle systems suffer from problems such as unstable fixation, low drug delivery efficiency, and small amount of interstitial fluid collection during drug delivery and interstitial fluid collection. Furthermore, existing enhancement strategies involve complex equipment, cumbersome operation, high cost, and poor safety.

Method used

A bistable suction cup device to enhance microneedle performance was designed. It utilizes the "outward-rebound" mechanism of the elastic hemispherical shell to generate negative pressure adsorption, ensuring that the microneedle completely penetrates the skin. It also improves drug delivery efficiency and collection capability by inducing interstitial fluid flow through active negative pressure.

Benefits of technology

This device enhances the adhesion between the microneedle and the skin through a bistable structure, improves drug delivery efficiency and interdermal fluid collection, simplifies operation, reduces costs, and is adaptable to different types and shapes of microneedles.

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Abstract

The application discloses a kind of bistable suction disc devices for enhancing the performance of microneedle and preparation method thereof, belong to medical instrument technical field, the bistable suction disc device structure includes elastic hemispherical shell, and the outer wall of elastic hemispherical shell is provided with convex column, and the axis of convex column and elastic hemispherical shell coincides, and the inner wall of elastic hemispherical shell is provided with microneedle patch mounting platform, and microneedle patch mounting platform is located just below the convex column, and the platform is combined with microneedle patch;Elastic hemispherical shell includes first stable state and second stable state, and first stable state is open downward state, and second stable state is open upward state, and it changes first stable state and second stable state when using, so that the negative pressure area between the inner wall of elastic hemispherical shell and skin, enhance the drug delivery efficiency of microneedle on microneedle patch and skin interstitial fluid collection amount.The bistable suction disc device has wide application prospect in the field of biomedicine.
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