Radio frequency magnetic field enhancing device for magnetic resonance imaging and manufacturing method

Abstract

The invention provides a radio frequency magnetic field enhancing device for magnetic resonance imaging and a manufacturing method. The corresponding radio frequency magnetic field enhancing device comprises a substrate and at least one metamaterial layer arranged on the substrate, the metamaterial layer comprises at least one array unit, the array unit is formed by a strip-shaped non-magnetic material, and the array unit is in a spiral line shape; when the number of the array units is multiple, the multiple array units are arranged on the same plane in a mutual rotating and nesting mode; and when a plurality of metamaterial layers are arranged, the plurality of metamaterial layers are stacked on the substrate. The radio frequency magnetic field enhancement device for magnetic resonance imaging provided by the invention can reduce the capacitance and increase the inductance value of the structure, thereby improving the magnetic field enhancement performance of the structure.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of nuclear magnetic resonance imaging, in particular to a radio frequency magnetic field enhancement device for magnetic resonance imaging and a manufacturing method. BACKGROUND

[0002] MRI (Magnetic Resonance Imaging) is a non-invasive detection method, and is an important basic diagnostic technique in the fields of medicine, biology and neuroscience. The signal strength transmitted by the existing MRI equipment mainly depends on the strength of the static magnetic field B0. Using a high magnetic field or even a super high magnetic field system can improve the signal-to-noise ratio, resolution and shorten the scanning time of the image. However, the increase of the static magnetic field strength will bring the following three problems:

[0003] 1) The RF (Radio Frequency) field non-uniformity increases, and the tuning difficulty increases;

[0004] 2) The heat production of human tissues increases, which brings safety hazards, and patients are also prone to dizziness, vomiting and other adverse reactions;

[0005] 3) The purchase cost increases substantially, which is a burden for most small-scale hospitals. Therefore, how to use the smallest static magnetic field strength while obtaining high imaging quality has become a crucial problem in MRI technology.

[0006] In view of the above problems, researchers have proposed a variety of solutions. The first is the RF coil optimization method, which greatly promotes the improvement of the detector resolution and scanning speed in MRI. Studies have shown that using parallel imaging can reduce the scanning time, and using a multi-channel coil can achieve better imaging quality and a larger detection area. However, this scheme has been relatively mature, and considering that optimizing the coil requires redesigning the MRI system, it brings many inconveniences to practical application. The second is to use special contrast agents to enhance the local magnetic field, such as rare earth magnetic atoms or magnetic nanoparticles. Since the contrast agent needs to be taken orally or injected into the human tissue or organ, there is a potential side effect or even a risk to life, so it is not the most ideal solution.

[0007] The above various methods use a larger lumped capacitance, which leads to a decrease in the equivalent inductance, a decrease in the ability of the device to store magnetic energy, and a decrease in the image signal-to-noise ratio enhancement multiple of the structure. SUMMARY

[0008] The present application provides a secondary magnetic surface plasmonic metamaterial with a special configuration for enhancing the magnetic resonance RF magnetic field, to solve the technical pain points of the lumped capacitance of the RF magnetic field enhancement device in the prior art, which leads to a decrease in the equivalent inductance, a decrease in the ability of the device to store magnetic energy, and a decrease in the image signal-to-noise ratio enhancement multiple of the structure.

[0009] To solve at least one of the above problems in the prior art, embodiments of the present application provide a radio frequency magnetic field enhancement device for magnetic resonance imaging and a manufacturing method thereof.

[0010] According to a first aspect of embodiments of the present application, the present application provides a radio frequency magnetic field enhancement device for magnetic resonance imaging, comprising:

[0011] a substrate and at least one metamaterial layer disposed on the substrate;

[0012] The metamaterial layer comprises at least one array unit, the array unit is formed by a strip of non-magnetic material, and the array unit is in the shape of a spiral line;

[0013] When the number of array units is a plurality, the plurality of array units are disposed on the same plane in a mutually rotating and nested manner; and

[0014] When the number of metamaterial layers is a plurality, the plurality of metamaterial layers are stacked on the substrate.

[0015] In some embodiments of the present application, the distance between adjacent non-magnetic materials in the metamaterial layer is adjustable to adjust the enhancement multiple of the radio frequency magnetic field of the radio frequency magnetic field enhancement device.

[0016] In some embodiments of the present application, the number of turns formed by the non-magnetic material in the metamaterial layer is adjustable to adjust the enhancement multiple of the radio frequency magnetic field of the radio frequency magnetic field enhancement device.

[0017] In some embodiments of the present application, the line width of the non-magnetic material is adjustable to adjust the enhancement multiple of the radio frequency magnetic field of the radio frequency magnetic field enhancement device.

[0018] In some embodiments of the present application, the array unit is an axisymmetric structure.

[0019] In some embodiments of the present application, the spiral centers of the plurality of array units coincide with each other.

[0020] In some embodiments of the present application, the angles formed by the adjacent two line segments connected by the outer end points of the at least two array units and the spiral center are equal; the angles are formed by the adjacent line segments and the spiral center.

[0021] In some embodiments of the present application, the spiral line shape comprises a circular spiral line, a rectangular spiral line, and an involute.

[0022] According to a second aspect of embodiments of the present application, the present application provides a manufacturing method of the radio frequency magnetic field enhancement device for magnetic resonance imaging according to the first aspect, the method comprising:

[0023] The resonant frequency of the radio frequency magnetic field is determined based on the pre-set enhancement factor of the radio frequency magnetic field of the radio frequency magnetic field enhancement device.

[0024] The equivalent capacitance and equivalent inductance of the radio frequency magnetic field enhancement device are determined based on the resonant frequency.

[0025] The radio frequency magnetic field enhancement device is manufactured based on the equivalent capacitance and equivalent inductance.

[0026] In some embodiments of this application, the radio frequency magnetic field enhancement device is manufactured based on the equivalent capacitance and equivalent inductance, including:

[0027] The configuration parameters of the radio frequency magnetic field enhancement device are determined based on the equivalent capacitance and the equivalent inductance.

[0028] The radio frequency magnetic field enhancement device is manufactured according to the configuration parameters.

[0029] In some embodiments of this application, the configuration parameters include: the distance between adjacent non-magnetic materials of the radio frequency magnetic field enhancement device, the number of turns formed by the non-magnetic material, and the linewidth of the non-magnetic material.

[0030] As can be seen from the above description, the present invention provides a radio frequency magnetic field enhancement device and manufacturing method for magnetic resonance imaging. The corresponding radio frequency magnetic field enhancement device for magnetic resonance imaging includes: a substrate and at least one metamaterial layer disposed on the substrate; the metamaterial layer includes at least one array unit, the array unit is formed of strip-shaped non-magnetic material, and the array unit is helical; when there are multiple array units, the multiple array units are disposed on the same plane by mutual rotation and nesting; and when there are multiple metamaterial layers, the multiple metamaterial layers are stacked on the substrate.

[0031] A method for manufacturing a radio frequency magnetic field enhancement device for magnetic resonance imaging includes: determining the resonant frequency of the radio frequency magnetic field based on a pre-set enhancement factor of the radio frequency magnetic field of the enhancement device; determining the equivalent capacitance and equivalent inductance of the radio frequency magnetic field enhancement device based on the resonant frequency; and manufacturing the radio frequency magnetic field enhancement device based on the equivalent capacitance and equivalent inductance.

[0032] The radio frequency magnetic field enhancement device for magnetic resonance imaging proposed in this invention overcomes the technical problem in existing radio frequency magnetic field enhancement devices that have large lumped capacitance, leading to a decrease in equivalent inductance, a reduction in the device's ability to store magnetic energy, and consequently a decrease in the image signal-to-noise ratio enhancement factor of the structure. The radio frequency magnetic field enhancement device is made of metamaterials and has a special configuration that can reduce capacitance and increase the inductance of the structure, thereby improving the magnetic field enhancement performance of the structure. Attached Figure Description

[0033] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. In the drawings:

[0034] Figure 1 This is a schematic diagram of a radio frequency magnetic field enhancement device for magnetic resonance imaging according to an embodiment of this application.

[0035] Figure 2 This is another schematic diagram of a radio frequency magnetic field enhancement device for magnetic resonance imaging according to an embodiment of this application.

[0036] Figure 3 This is a third schematic diagram of a radio frequency magnetic field enhancement device for magnetic resonance imaging according to an embodiment of this application.

[0037] Figure 4 This is a fourth schematic diagram of a radio frequency magnetic field enhancement device for magnetic resonance imaging according to an embodiment of this application.

[0038] Figure 5 This is a fifth schematic diagram of a radio frequency magnetic field enhancement device for magnetic resonance imaging according to an embodiment of this application.

[0039] Figure 6 This is a schematic diagram of a method for manufacturing a radio frequency magnetic field enhancement device for magnetic resonance imaging according to an embodiment of this application.

[0040] Figure 7 This is a schematic diagram illustrating the principle of the radio frequency magnetic field enhancement factor of the radio frequency magnetic field enhancement device for magnetic resonance imaging according to an embodiment of this application.

[0041] Figure 8 This is a flowchart illustrating step 300 of a method for manufacturing a radio frequency magnetic field enhancement device for magnetic resonance imaging according to an embodiment of this application.

[0042] Figure 9 This is a schematic diagram illustrating an application scenario of a radio frequency magnetic field enhancement device for magnetic resonance imaging according to an embodiment of this application.

[0043] Figure 10 This is a schematic diagram of the magnetic field strength distribution before the application of the radio frequency magnetic field enhancement device for magnetic resonance imaging according to an embodiment of this application;

[0044] Figure 11 This is a schematic diagram of the magnetic field strength distribution after the application of the radio frequency magnetic field enhancement device for magnetic resonance imaging according to an embodiment of this application;

[0045] Figure 12This is a schematic diagram of the structure of an electronic device in an embodiment of the present invention.

[0046] Figure label:

[0047] 1: Base;

[0048] 2: Metamaterial layer;

[0049] 3, 4: Coils;

[0050] 5: Radio frequency magnetic field enhancement devices;

[0051] 6: Mobile hospital beds;

[0052] 7: Radio frequency transmitting coil (body coil);

[0053] 8: Gradient coil;

[0054] 9: Main magnet coil. Detailed Implementation

[0055] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0056] Those skilled in the art will understand that embodiments of the present invention can be provided as methods, systems, or computer program products. Therefore, the present invention can take the form of a completely hardware embodiment, a completely software embodiment, or an embodiment combining software and hardware aspects. Furthermore, the present invention can take the form of a computer program product embodied on one or more computer-usable storage media (including, but not limited to, disk storage, CD-ROM, optical storage, etc.) containing computer-usable program code.

[0057] It should be noted that the terms "comprising" and "having," and any variations thereof, in the specification, claims, and accompanying drawings of this application are intended to cover a non-exclusive inclusion. For example, a process, method, system, product, or apparatus that includes a series of steps or units is not necessarily limited to those explicitly listed, but may include other steps or units not explicitly listed or inherent to these processes, methods, products, or apparatuses. Without conflict, the embodiments and features in the embodiments of this application can be combined with each other. This application will now be described in detail with reference to the accompanying drawings and embodiments.

[0058] In order to solve at least one of the above-mentioned problems in the prior art, in a first aspect, embodiments of this application provide a radio frequency magnetic field enhancement device for magnetic resonance imaging. Figure 1 This is a schematic diagram of a radio frequency magnetic field enhancement device according to an embodiment of this application. Figure 1 As shown, the radio frequency magnetic field enhancement device for magnetic resonance imaging includes:

[0059] Substrate 1 and at least one metamaterial layer 2 disposed on said substrate 1;

[0060] The metamaterial layer 2 includes at least one array unit ( Figure 1 The array unit has two array elements, which are formed of strip-shaped non-magnetic material and are spiral-shaped.

[0061] When there are multiple array units, the multiple array units are arranged on the same plane by mutual rotation and nesting; and

[0062] When there are multiple metamaterial layers 2, the multiple metamaterial layers 2 are stacked on the substrate 1, that is, the multiple metamaterial layers 2 are stacked together along a direction perpendicular to the plane mentioned above.

[0063] It is understood that the radio frequency magnetic field enhancement device with the above configuration provided in this application does not contain lumped capacitance, but rather small structural capacitance is formed between units. Therefore, the radio frequency magnetic field enhancer with this configuration has a large equivalent inductance and a strong ability to store magnetic energy and enhance the magnetic field, so the image signal-to-noise ratio enhancement factor of the structure will not decrease.

[0064] In some embodiments of this application, the distance between adjacent non-magnetic materials in the metamaterial layer 2 is adjustable (e.g., Figure 1 The distance between coil 3 and coil 4 (which are made of non-magnetic materials) is adjusted to increase the enhancement factor of the radio frequency magnetic field of the radio frequency magnetic field enhancement device.

[0065] In some embodiments of this application, the number of turns formed by the non-magnetic material in the metamaterial layer 2 (e.g.) Figure 1 The total number of turns of the intermediate coil 3, coil 4 and other coils is adjustable to adjust the enhancement factor of the radio frequency magnetic field of the radio frequency magnetic field enhancement device.

[0066] In some embodiments of this application, the linewidth of the non-magnetic material is adjustable (e.g., Figure 1 The widths of coil 3, coil 4, and other coils corresponding to the non-magnetic material in the device are adjusted to increase the enhancement factor of the radio frequency magnetic field of the radio frequency magnetic field enhancement device.

[0067] In some embodiments of this application, Figure 1The spiral of the array unit shown is supported by metallic copper (or other non-magnetic material), with a line width of 2 mm, a total of 6 turns, a distance of 16 mm between adjacent turns, and a metallic copper thickness of 12 micrometers.

[0068] In some embodiments of this application, when the structure is axially symmetric, the number of array units can be 2 to 10.

[0069] In some embodiments of this application, the array unit is generally an axisymmetric structure.

[0070] In some embodiments of this application, the helical centers of the plurality of array elements coincide with each other. See also Figure 2 It is a schematic diagram of a configuration with one array unit. Figure 1 It is a schematic diagram of a configuration with two arrays, where the spiral centers of the two array units coincide at point A.

[0071] In some embodiments of this application, the angles formed by the adjacent line segments connecting the outer endpoints of each of the at least two array units to the spiral center are equal; the angles are formed by the adjacent line segments and the spiral center.

[0072] Figure 3 The configuration of the radio frequency magnetic field enhancement device shown has three array units. The three angles formed by connecting the outer endpoints B, C and D of the three array units to point A are equal, that is, each angle is 360° / 3 = 120°.

[0073] Figure 1 The configuration of the radio frequency magnetic field enhancement device shown has two array units. The two angles formed by connecting the outer endpoints of the two array units to point A are equal, that is, each angle is 360° / 2 = 180°.

[0074] Figure 4 The configuration of the radio frequency magnetic field enhancement device shown has four array units. The four angles formed by connecting the outer endpoints of the four array units to point A are equal, that is, each angle is 360° / 4 = 90°.

[0075] It should be noted that the varying number of rotation angles is primarily for achieving the desired target resonant frequency. Generally, as the number of these arrays increases, the equivalent inductance and equivalent capacitance also gradually increase, and the resonant frequency gradually decreases. While the resonant frequency decreases, the enhancement factor of the radio frequency magnetic field at that frequency also slowly increases.

[0076] In some embodiments of this application, the spiral shape includes: a circular spiral, a rectangular spiral, etc. Figure 5 This type of radio frequency magnetic field enhancement device and Figure 1The difference between the circular spiral radio frequency magnetic field enhancement device and the involute is that the equivalent inductance and equivalent capacitance formed by the two will be different, the structural dimensions at the same resonant frequency will be different, and the distribution of the radio frequency magnetic field will be different.

[0077] As can be seen from the above description, the present invention provides a radio frequency magnetic field enhancement device and manufacturing method for magnetic resonance imaging. The corresponding radio frequency magnetic field enhancement device for magnetic resonance imaging includes: a substrate and at least one metamaterial layer disposed on the substrate; the metamaterial layer includes at least one array unit, the array unit is formed of strip-shaped non-magnetic material, and the array unit is helical; when there are multiple array units, the multiple array units are disposed on the same plane by mutual rotation and nesting; and when there are multiple metamaterial layers, the multiple metamaterial layers are stacked on the substrate.

[0078] The radio frequency magnetic field enhancement device for magnetic resonance imaging proposed in this invention does not contain lumped capacitance. Instead, it forms a small structural capacitance by at least one true accumulator unit. This perfectly solves the technical problem in existing radio frequency magnetic field enhancement devices where the large lumped capacitance leads to a decrease in equivalent inductance, a reduction in the device's ability to store magnetic energy, and consequently a decrease in the image signal-to-noise ratio enhancement factor. The radio frequency magnetic field enhancement device is made of metamaterials and has a special configuration that can reduce capacitance and increase structural inductance, thereby improving the magnetic field enhancement performance of the structure.

[0079] On the other hand, embodiments of the present invention also provide a method for manufacturing a radio frequency magnetic field enhancement device for magnetic resonance imaging.

[0080] The emergence of metamaterials offers a novel and more effective method for improving the quality and efficiency of MRI imaging. Metamaterials possess many unique properties not found in natural materials. By utilizing the interaction between electromagnetic waves and the metallic or dielectric components of metamaterials, as well as the coupling effect between these components, it is possible to control the propagation path of electromagnetic waves and the distribution of electromagnetic field strength. Their working principle utilizes the electromagnetic resonance of their structural units to achieve anisotropic and gradient-distributed, even negative, electromagnetic parameters. Furthermore, by designing parameters such as the geometry, shape, and dielectric constant of the metamaterial, resonance enhancement at different frequencies can be achieved. Metamaterials have potential applications in the design and fabrication of devices and equipment that manipulate electromagnetic waves, and MRI is one important application area.

[0081] There are three main metrics for evaluating MRI image quality: resolution, signal-to-noise ratio (SNR), and contrast ratio. Higher image resolution allows for more detailed images to be displayed; a higher SNR results in a clearer image, and a high SNR can also support higher resolution or shorten scan time; contrast ratio is crucial for distinguishing normal tissue from diseased tissue. Metamaterials can improve the image SNR by altering the magnetic field distribution within the MRI system. Metamaterial-inspired magnetic surface plasmons can enhance the local field, thereby improving the image SNR.

[0082] See Figure 6 A method for manufacturing a radio frequency magnetic field enhancement device for magnetic resonance imaging, comprising:

[0083] Step 100: Determine the resonant frequency of the radio frequency magnetic field based on the pre-set enhancement factor of the radio frequency magnetic field of the radio frequency magnetic field enhancement device;

[0084] Specifically, first determine the model of the magnetic resonance system, and then determine the resonant frequency of the radio frequency magnetic field based on the required enhancement factor of the radio frequency magnetic field. See [link to relevant documentation]. Figure 7 The magnetic field strength of the original radio frequency magnetic field of the magnetic resonance system is B. After passing through the radio frequency magnetic field enhancement device, the magnetic field strength is enhanced to αB, that is, the enhancement factor is α.

[0085] Step 200: Determine the equivalent capacitance and equivalent inductance of the radio frequency magnetic field enhancement device based on the resonant frequency;

[0086] Step 300: Fabricate the radio frequency magnetic field enhancement device based on the equivalent capacitance and equivalent inductance.

[0087] In some embodiments of this application, see Figure 8 Step 300 includes:

[0088] Step 301: Determine the configuration parameters of the radio frequency magnetic field enhancement device based on the equivalent capacitance and the equivalent inductance;

[0089] Step 302: Fabricate the radio frequency magnetic field enhancement device according to the configuration parameters.

[0090] In some embodiments of this application, the configuration parameters include: the distance between adjacent non-magnetic materials of the radio frequency magnetic field enhancement device, the number of turns formed by the non-magnetic material, and the linewidth of the non-magnetic material.

[0091] The parametric equations for the helix of the radio frequency magnetic field enhancement device are as follows:

[0092]

[0093] Where x and y are the abscissa and ordinate of the helix, θ is the polar angle, and A is the amplitude of the helix, which is numerically equal to the distance between adjacent non-magnetic materials of the RF magnetic field enhancement device (the distance between adjacent solenoids); the number of coils is related to θ. The equivalent capacitance and equivalent inductance of the metamaterial can be adjusted by the number of coils θ, the distance A between adjacent solenoids, and the width of the solenoids.

[0094] This invention also provides an application scenario for a radio frequency magnetic field enhancement device for magnetic resonance imaging. Referring to 8, the radio frequency magnetic field enhancement device 5 is positioned at the human body part where the radio frequency magnetic field needs to be enhanced (when used for enhancing the signal-to-noise ratio of magnetic resonance imaging, the radio frequency magnetic field enhancement device can simply be attached to the part to be tested (abdomen, head, etc.) and a suitable receiving coil can be used to receive it (including but not limited to spinal coil, head coil, and body coil, etc.)). Figure 9 In the diagram, 6 is a mobile hospital bed, which can move the human body to the optimal position according to the testing needs; 7 is a radio frequency transmitting coil (body coil); 8 is a gradient coil; and 9 is the main magnet coil.

[0095] The structure following the RF magnetic field enhancement device array can be attached to substrates of different shapes, thus making it suitable for imaging in different scenarios. Furthermore, the RF magnetic field enhancement devices can be combined (e.g., two halves snapped together). (In this case, when RF magnetic field enhancement devices are stacked vertically together, the response to the RF magnetic field will be perpendicular to both directions, which is relatively low. When the aforementioned single RF magnetic field enhancement device is placed in parallel, it will only respond to the RF magnetic field in the direction perpendicular to the plane.)

[0096] like Figure 10 As shown, the radio frequency magnetic field enhancement device provided in this application is not used (corresponding to...). Figure 1 The radio frequency magnetic field strength corresponding to the configuration of the radio frequency magnetic field enhancement device shown is 0.00265 A / m. See also... Figure 11 After use, the radio frequency magnetic field strength is 0.18 A / m, an enhancement factor of nearly 68 times.

[0097] As can be seen from the above description, the present invention provides a method for manufacturing a radio frequency magnetic field enhancement device for magnetic resonance imaging, comprising: determining the resonant frequency of the radio frequency magnetic field according to a pre-set enhancement factor of the radio frequency magnetic field of the radio frequency magnetic field enhancement device; determining the equivalent capacitance and equivalent inductance of the radio frequency magnetic field enhancement device according to the resonant frequency; and manufacturing the radio frequency magnetic field enhancement device according to the equivalent capacitance and equivalent inductance.

[0098] The radio frequency magnetic field enhancement device manufactured using the manufacturing method for the radio frequency magnetic field enhancement device for magnetic resonance imaging proposed in this invention has the advantages of having no lumped capacitance, only a small structural capacitance, and a large equivalent inductance, resulting in a strong ability to store magnetic energy and enhance the magnetic field. This overcomes the technical problem in the prior art where the radio frequency magnetic field enhancement device has a large lumped capacitance, leading to a decrease in equivalent inductance, a reduction in the device's ability to store magnetic energy, and consequently a decrease in the image signal-to-noise ratio enhancement factor of the structure.

[0099] The embodiments of this application also provide a specific implementation of an electronic device capable of implementing all the steps in the manufacturing method of the radio frequency magnetic field enhancement device for magnetic resonance imaging described in the above embodiments. See [link to relevant documentation]. Figure 12 The electronic devices specifically include the following:

[0100] Processor 1201, memory 1202, communications interface 1203, and bus 1204;

[0101] The processor 1201, memory 1202, and communication interface 1203 communicate with each other via bus 1204; the communication interface 1203 is used to realize information transmission between server-side devices and client-side devices and other related devices.

[0102] The processor 1201 is used to call the computer program in the memory 1202. When the processor executes the computer program, it implements all the steps in the manufacturing method of the radio frequency magnetic field enhancement device for magnetic resonance imaging in the above embodiment. For example, when the processor executes the computer program, it implements the following steps:

[0103] Step 100: Determine the resonant frequency of the radio frequency magnetic field based on the pre-set enhancement factor of the radio frequency magnetic field of the radio frequency magnetic field enhancement device;

[0104] Step 200: Determine the equivalent capacitance and equivalent inductance of the radio frequency magnetic field enhancement device based on the resonant frequency;

[0105] Step 300: Fabricate the radio frequency magnetic field enhancement device based on the equivalent capacitance and equivalent inductance.

[0106] Embodiments of this application also provide a computer-readable storage medium capable of implementing all steps of the manufacturing method for the radio frequency magnetic field enhancement device for magnetic resonance imaging described in the above embodiments. The computer-readable storage medium stores a computer program that, when executed by a processor, implements all steps of the manufacturing method for the radio frequency magnetic field enhancement device for magnetic resonance imaging described in the above embodiments. For example, when the processor executes the computer program, it implements the following steps:

[0107] Step 100: Determine the resonant frequency of the radio frequency magnetic field based on the pre-set enhancement factor of the radio frequency magnetic field of the radio frequency magnetic field enhancement device;

[0108] Step 200: Determine the equivalent capacitance and equivalent inductance of the radio frequency magnetic field enhancement device based on the resonant frequency;

[0109] Step 300: Fabricate the radio frequency magnetic field enhancement device based on the equivalent capacitance and equivalent inductance.

[0110] The various embodiments in this specification are described in a progressive manner. Similar or identical parts between embodiments can be referred to interchangeably. Each embodiment focuses on its differences from other embodiments. In particular, hardware + program embodiments are relatively simple in description because they are fundamentally similar to method embodiments; relevant parts can be referred to the descriptions in the method embodiments.

[0111] The foregoing has described specific embodiments of this specification. Other embodiments are within the scope of the appended claims. In some cases, the actions or steps recited in the claims may be performed in a different order than that shown in the embodiments and may still achieve the desired result. Furthermore, the processes depicted in the drawings do not necessarily require the specific or sequential order shown to achieve the desired result. In some embodiments, multitasking and parallel processing are possible or may be advantageous.

[0112] While this application provides method operation steps as shown in the embodiments or flowcharts, more or fewer operation steps may be included based on conventional or non-inventive labor. The order of steps listed in the embodiments is merely one possible execution order among many and does not represent the only execution order. In actual device or client product execution, the method can be executed sequentially as shown in the embodiments or drawings, or in parallel (e.g., in a parallel processor or multi-threaded processing environment).

[0113] For ease of description, the above devices are described in terms of function, divided into various modules. Of course, in implementing the embodiments of this specification, the functions of each module can be implemented in one or more software and / or hardware components, or a module that performs the same function can be implemented by a combination of multiple sub-modules or sub-units. The device embodiments described above are merely illustrative. For example, the division of units is only a logical functional division; in actual implementation, there may be other division methods. For example, multiple units or components may be combined or integrated into another system, or some features may be ignored or not executed. Furthermore, the coupling or direct coupling or communication connection shown or discussed may be through some interfaces, or indirect coupling or communication connection between devices or units, and may be electrical, mechanical, or other forms.

[0114] Those skilled in the art will also know that, besides implementing the controller using purely computer-readable program code, the same functions can be achieved by logically programming the method steps, making the controller function as logic gates, switches, application-specific integrated circuits (ASICs), programmable logic controllers (PLCs), and embedded microcontrollers. Therefore, such a controller can be considered a hardware component, and the devices within it used to implement various functions can also be considered structures within that hardware component. Alternatively, the devices used to implement various functions can be considered as both software modules implementing the method and structures within a hardware component.

[0115] In a typical configuration, a computing device includes one or more processors (CPU), input / output interfaces, network interfaces, and memory.

[0116] Memory may include non-persistent storage in computer-readable media, such as random access memory (RAM) and / or non-volatile memory, such as read-only memory (ROM) or flash RAM. Memory is an example of computer-readable media.

[0117] The various embodiments in this specification are described in a progressive manner. Similar or identical parts between embodiments can be referred to mutually. Each embodiment focuses on describing the differences from other embodiments. In particular, system embodiments are basically similar to method embodiments, so the description is relatively simple; relevant parts can be referred to the descriptions in the method embodiments. In the description of this specification, the terms "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of the embodiments in this specification. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described can be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification and the features of different embodiments or examples.

[0118] The above description is merely an embodiment of the present specification and is not intended to limit the embodiments of the present specification. For those skilled in the art, various modifications and variations can be made to the embodiments of the present specification. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principle of the embodiments of the present specification should be included within the scope of the claims of the embodiments of the present specification.

Claims

1. A radio frequency magnetic field enhancement device for magnetic resonance imaging, characterized in that, The device comprises a substrate and at least one metamaterial layer disposed on the substrate; The metamaterial layer comprises at least one array unit formed by a strip of non-magnetic material, and the array unit is in the shape of a spiral line; When the number of array units is multiple, the multiple array units are disposed on the same plane by being nested with each other in rotation; And When the number of metamaterial layers is multiple, the multiple metamaterial layers are stacked on the substrate.

2. The radio frequency magnetic field enhancement device of claim 1, wherein, The distance between adjacent non-magnetic materials in the metamaterial layer is adjustable to adjust the enhancement multiple of the radio frequency magnetic field of the radio frequency magnetic field enhancement device.

3. The radio frequency magnetic field enhancement device of claim 1, wherein, The number of turns formed by the non-magnetic material in the metamaterial layer is adjustable to adjust the enhancement multiple of the radio frequency magnetic field of the radio frequency magnetic field enhancement device.

4. The radio frequency magnetic field enhancement device of claim 1, wherein, The line width of the non-magnetic material is adjustable to adjust the enhancement multiple of the radio frequency magnetic field of the radio frequency magnetic field enhancement device.

5. The radio frequency magnetic field enhancement device of claim 1, wherein, The array unit is an axisymmetric structure.

6. The radio frequency magnetic field enhancement device of claim 5, wherein, The spiral centers of the multiple array units coincide with each other.

7. The radio frequency magnetic field enhancement device of claim 6, wherein, The angles formed by the adjacent line segments connected by the outer endpoints of the at least two array units and the spiral center are equal; the angle is formed by the adjacent line segments and the spiral center.

8. The radio frequency magnetic field enhancement device of any one of claims 1 to 7, wherein, The spiral line shape comprises a circular spiral line, a rectangular spiral line, and an involute.

9. A method of manufacturing a radio frequency magnetic field enhancement device for magnetic resonance imaging as claimed in any one of claims 1 to 8, characterized in that, The method comprises: Determining the resonance frequency of the radio frequency magnetic field according to the preset enhancement multiple of the radio frequency magnetic field of the radio frequency magnetic field enhancement device; Determining the equivalent capacitance and the equivalent inductance of the radio frequency magnetic field enhancement device according to the resonance frequency; Manufacturing the radio frequency magnetic field enhancement device according to the equivalent capacitance and the equivalent inductance.

10. The manufacturing method according to claim 9, wherein Manufacturing the radio frequency magnetic field enhancement device according to the equivalent capacitance and the equivalent inductance comprises: Determining the configuration parameters of the radio frequency magnetic field enhancement device according to the equivalent capacitance and the equivalent inductance; Manufacturing the radio frequency magnetic field enhancement device according to the configuration parameters; the configuration parameters comprise the distance between adjacent non-magnetic materials of the radio frequency magnetic field enhancement device, the number of turns formed by the non-magnetic material, and the line width of the non-magnetic material.

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