Nested device with closed opening for lifting and centering nested device

Abstract

The invention relates to a nesting device with a closed opening for lifting and centering the nesting device. There is provided a structure comprising: a. A plurality of receptacles adapted and arranged for containing containers for pharmaceutical, medical and / or cosmetic compositions; b. A first planar member at least partially surrounding the plurality of brackets wherein the first planar member: i. Has a maximum height less than or equal to 3 mm; ii. Comprising at least two openings of the first type, where each of the at least two openings of the first type is adapted for: A. extending through the first planar member, and B. comprising a boundary surface extending around at least 80% of the circumference of the respective opening of the first type.

Description

TECHNICAL FIELD

[0001] The present invention relates to a structure for transporting a plurality of containers, wherein the containers are preferably for containing pharmaceutical compositions, medical compositions and / or cosmetic compositions. The present invention further relates to a method for transporting a plurality of containers using the structure, and to the use of the structure for containing a plurality of containers. BACKGROUND

[0002] Containers, such as containers for pharmaceutical compositions, medical compositions and / or cosmetic compositions, are often contained (e.g. held) and transported using structures known as nests, such as the nests sold by SCHOTT Pharma AG & Co. KGaA. Such nests are described, for example, in EP 4169545 A1. These nests often have openings or cavities in order to lift the nests by inserting a finger and / or a tool into the openings or cavities. The openings and cavities are also often used to center the nests when filling the containers contained in the nests. These openings often lead to the outside of the nests or are not closed, and the boundary surface extending around the respective openings is less than 80% of the circumference. The presence of these openings and cavities leads to a number of disadvantages of the nests, such as a reduced form stability and / or the nests require more material. Structures for containing containers are disclosed in US 11819658 B2, WO 18198028 A1, EP 3653526 A1, EP 3535057 B1, EP 3413951 B1, WO 2023 / 161340 and EP 3381828 A1. SUMMARY

[0003] OBJECTIVE It is an object of the present invention to at least partially overcome at least one of the disadvantages present in the prior art.

[0004] It is a further object of the present invention to provide a structure (e.g. a nest) for containing containers, wherein the structure reduces deviations in the desired form, for example, due to the production and / or sterilization of the structure.

[0005] It is a further object of the present invention to provide a structure (e.g. a nest) for containing containers, wherein the structure reduces deformation under load.

[0006] It is a further object of the present invention to provide a structure (e.g. a nest) for containing containers, wherein the structure reduces the material required for production.

[0007] It is another object of the present invention to provide a structure (e.g. a nest device) for containing containers, wherein the structure is more easily handled, e.g. more easily removed from a tub.

[0008] It is another object of the present invention to provide a structure (e.g. a nest device) for containing containers, wherein the structure reduces the amount of liquid (e.g. water) that accumulates during steam sterilization of the structure.

[0009] It is another object of the present invention to provide a structure (e.g. a nest device) for containing containers, wherein less particles are formed when the structure is transported in another structure (e.g. a tub).

[0010] Preferred embodiments of the present invention Any embodiment of the present invention facilitates at least partial achievement of at least one of the above-mentioned objects.

[0011] A first embodiment of the present invention is a structure, the structure comprising: a. a plurality of receptacles, wherein each receptacle of the plurality of receptacles: i. is adapted and arranged for containing a container, the container preferably being a container for containing a pharmaceutical composition, a medical composition and / or a cosmetic composition; ii. has a height of at least 10 mm, preferably at least 12 mm, and further preferably at least 15 mm, iii. has a first end and another end opposite the first end, iv. comprises a side wall at least partially enclosing an interior of the receptacle; b. a first planar member at least partially surrounding, preferably surrounding, the plurality of receptacles, wherein the first planar member i. comprises a first face and another face opposite the first face, wherein A. the first face is facing the first ends of the plurality of receptacles, and B. the other face is facing the other ends of the plurality of receptacles, ii. has a maximum height of less than or equal to 3 mm, preferably less than or equal to 2.5 mm, more preferably less than or equal to 2 mm, and further preferably less than or equal to 1.6 mm; iii. comprises at least two first type openings, wherein the following applies to each opening of the at least two first type openings: A. extends through the first planar member, and B. comprises a boundary surface extending around at least 80%, preferably at least 85%, more preferably at least 90%, and further preferably at least 95% of the perimeter of the respective first type opening.

[0012] In a preferred embodiment of the structure, for each of the at least two first type openings, the boundary surface extends around 100% of the perimeter of the respective first type opening.

[0013] This preferred embodiment is a second embodiment of the application, which is preferably dependent on the first embodiment of the application.

[0014] In a preferred embodiment of the structure, one of the following applies: i. any further planar component protruding from the first planar component has a maximum dimension of 10 cm or less, preferably 8 cm or less, more preferably 6 cm or less, and further preferably 4 cm or less, wherein said maximum dimension is preferably measured along one or more directions parallel to the first face of the first planar component; or ii. the structure does not comprise a further planar component protruding from the first planar component.

[0015] This preferred embodiment is a third embodiment of the application, which is preferably dependent on any one of the first and second embodiments of the application.

[0016] In the third embodiment, if the structure comprises a plurality of further planar components, the maximum dimension given in feature i. is understood to apply to each of the further planar components.

[0017] In a preferred embodiment of the structure, each of the at least two first type openings has a surface area of at least 96 mm 2 , preferably at least 100 mm 2 , more preferably at least 110 mm 2 , and further preferably at least 130 mm 2 .

[0018] This preferred embodiment is a fourth embodiment of the application, which is preferably dependent on any one of the first to third embodiments of the application.

[0019] In a preferred embodiment of the structure, each of the at least two first type openings has a surface area of 100 mm 2 to 550 mm 2 , preferably 140 mm 2 to 500 mm 2 , more preferably 180 mm 2up to 480 mm 2 and further preferably 220 mm 2 up to 450 mm 2 .

[0020] This preferred embodiment is a fifth embodiment of the present invention, which preferably depends on any one of the first to fourth embodiments of the present invention.

[0021] In a preferred aspect of the fifth embodiment, the surface area of each of the at least two first type openings is in the range of 200 mm 2 up to 500 mm 2 , more preferably 250 mm 2 up to 480 mm 2 , even more preferably 300 mm 2 up to 465 mm 2 , further preferably 350 mm 2 up to 450 mm 2 , and in particular preferably 400 mm 2 up to 430 mm 2 .

[0022] In a preferred embodiment of said structure, each of the at least two first type openings has at least one or all of the following properties: a. a maximum of the first dimension (e.g. length) of at least 6 mm, preferably at least 8 mm, more preferably at least 10 mm, and further preferably at least 12 mm; b. a maximum of the second dimension (e.g. width) of at least 6 mm, preferably at least 8 mm, more preferably at least 10 mm, and further preferably at least 12 mm.

[0023] This preferred embodiment is a sixth embodiment of the present invention, which preferably depends on any one of the first to fifth embodiments of the present invention.

[0024] In an aspect of the sixth embodiment, all possible combinations of features a. and b. are preferred aspects of this embodiment. These combinations are for example: a; b; a+b.

[0025] In a preferred embodiment of said structure, each of the at least two first type openings has at least one or all of the following properties: a. a maximum of the first dimension (e.g. length) in the range of 10 mm to 40 mm, preferably 12 mm to 35 mm, more preferably 14 mm to 27 mm, and further preferably 17 mm to 23 mm; b. The maximum value of the second dimension (e.g., width) is in the range of 10 mm to 50 mm, preferably 12 mm to 40 mm, more preferably 14 mm to 30 mm, and even more preferably 16 mm to 25 mm.

[0026] This preferred embodiment is the seventh embodiment of the present invention, which preferably belongs to any one of the first to sixth embodiments of the present invention.

[0027] In one aspect of the seventh embodiment, all possible combinations of features a. and b. constitute a preferred aspect of this embodiment. These combinations are, for example, a; b; a+b. In a preferred aspect of the seventh embodiment, feature a, i.e., the maximum value of the first dimension of each of the at least two first-class openings, is in the range of 18 mm to 20 mm, such as 19.05 mm.

[0028] In a preferred embodiment of the structure, the average height of the boundary surface of each of the at least two first-type openings is less than 14 mm, preferably less than 10 mm, more preferably less than 6 mm, and even more preferably less than 4 mm.

[0029] This preferred embodiment is the eighth embodiment of the present invention, which preferably belongs to any one of the first to seventh embodiments of the present invention.

[0030] In a preferred aspect of the eighth embodiment, the average height of the boundary surface of each of the at least two first-class openings is in the range of 0.4 mm to 14 mm, preferably 0.6 mm to 10 mm, more preferably 0.8 mm to 6 mm, and even more preferably 1.0 mm to 4 mm.

[0031] In a preferred embodiment of the structure, the maximum height of the boundary surface of each of the at least two first-type openings is less than 14 mm, preferably less than 10 mm, more preferably less than 6 mm, and even more preferably less than 4 mm.

[0032] This preferred embodiment is the ninth embodiment of the present invention, which preferably belongs to any one of the first to eighth embodiments of the present invention.

[0033] In a preferred aspect of the ninth embodiment, the maximum height of the boundary surface of each of the at least two first-class openings is in the range of 0.4 mm to 14 mm, preferably 0.6 mm to 10 mm, more preferably 0.8 mm to 6 mm, and even more preferably 1.0 mm to 4 mm.

[0034] In a preferred embodiment of the structure, the boundary surface is at least partially formed by the first portion, preferably partially formed by the first portion.

[0035] This preferred embodiment is the tenth embodiment of the present invention, which preferably belongs to any one of the first to ninth embodiments of the present invention.

[0036] In a preferred embodiment of the structure, the maximum value of the second dimension (e.g., width) of the first portion is in the range of 0.5 mm to 11 mm, preferably 1.0 mm to 9 mm, more preferably 1.5 mm to 8 mm, and even more preferably 2 mm to 7 mm.

[0037] This preferred embodiment is the eleventh embodiment of the present invention, and the eleventh embodiment is preferably subordinate to the tenth embodiment of the present invention.

[0038] In a preferred embodiment of the structure, the surface area of ​​the cross-section of the first portion is 0.1 mm. 2 Up to 40mm 2 Preferably 0.5mm 2 Up to 30mm 2 More preferably 1mm 2 Up to 20mm 2 And more preferably 2mm 2 Up to 10mm 2 Within the range, wherein the cross-section satisfies: I. Perpendicular to the edge of the first planar component, and II. Formed at the location where the second dimension (e.g., width) of the first part has a minimum value.

[0039] This preferred embodiment is the twelfth embodiment of the present invention, which preferably belongs to any one of the tenth to eleventh embodiments of the present invention.

[0040] In the twelfth embodiment, the cross-section preferably extends from the edge of the first planar component to the boundary surface of the first type of opening. In a preferred aspect of the twelfth embodiment, the surface area is 3 mm². 2 Up to 7mm 2 Within the range.

[0041] In a preferred embodiment of the structure, the first portion is arranged parallel to a portion of the edge of the first planar component.

[0042] This preferred embodiment is the thirteenth embodiment of the present invention, which preferably belongs to any one of the tenth to twelfth embodiments of the present invention.

[0043] In a preferred embodiment of the structure, one of the following applies: a. The maximum height of the first part is equal to or greater than, preferably greater than, the maximum height of the first planar component; or b. The maximum height of the first part is equal to or less than, preferably less than, the maximum height of the first planar component.

[0044] This preferred embodiment is the fourteenth embodiment of the present invention, which preferably belongs to any one of the tenth to thirteenth embodiments of the present invention.

[0045] In a preferred embodiment of the structure, the maximum height of the first part is xH, where H is the maximum height of the first planar component, and x is in the range of 0.1 to 10, preferably 0.5 to 5, more preferably 0.8 to 3, and even more preferably 1 to 2.

[0046] This preferred embodiment is the fifteenth embodiment of the present invention, which preferably belongs to any one of the tenth to fourteenth embodiments of the present invention.

[0047] In a preferred embodiment of the structure, the maximum height of the first part is in the range of 0.4 mm to 14 mm, preferably 0.6 mm to 10 mm, more preferably 0.8 mm to 6 mm, and even more preferably 1.0 mm to 4 mm.

[0048] This preferred embodiment is the sixteenth embodiment of the present invention, which preferably belongs to any one of the tenth to fifteenth embodiments of the present invention.

[0049] In a preferred embodiment of the structure, at least one or all of the following conditions apply: a. The maximum value of the first dimension (e.g., length) of the first part is equal to or greater than the maximum value of the first dimension (e.g., length) of the at least two first-class openings; b. The maximum value of the first dimension (e.g., length) of the first part is in the range of 3 mm to 70 mm, preferably 10 mm to 50 mm, more preferably 13 mm to 30 mm, and even more preferably 17 mm to 25 mm.

[0050] This preferred embodiment is the seventeenth embodiment of the present invention, which preferably belongs to any one of the tenth to sixteenth embodiments of the present invention.

[0051] In one aspect of the seventeenth embodiment, all possible combinations of features a. and b. constitute a preferred aspect of the embodiment. These combinations are, for example, a; b; a+b.

[0052] In a preferred embodiment of the structure, the first portion and the first planar component are integrally formed.

[0053] This preferred embodiment is the eighteenth embodiment of the present invention, which preferably belongs to any one of the tenth to seventeenth embodiments of the present invention.

[0054] The nineteenth embodiment of the present invention is a method for transporting multiple containers, the method comprising the following steps: a. To provide a structure according to the invention, preferably a structure according to any one of the first to eighteenth embodiments of the invention; b. The structure receives a plurality of containers, wherein the containers are preferably used to contain pharmaceutical compositions, medical compositions and / or cosmetic compositions; c. Preferably, the structure and the plurality of containers are transported from the first location to another location.

[0055] In a preferred embodiment of the method for transporting multiple containers, the method further includes at least one or all of the following steps: A. Inserting the structure into another structure (e.g., a packaging box) that at least partially surrounds the structure; B. Seal the opening of another structure with a covering device, preferably a breathable covering device, preferably a flat covering device; C. The structure and the container therein are subjected to heat treatment, for example, sterilization, and preferably simultaneously sealed in another structure (e.g., a packaging box).

[0056] This preferred embodiment is the twentieth embodiment of the present invention, which is preferably subordinate to the nineteenth embodiment of the present invention.

[0057] In a preferred aspect of the twentieth embodiment, feature B, the covering device comprises a polymer, more preferably a nonwoven polymer. Examples of nonwovens include flash spun plexifilamentary film-fibril structures and spunbond microfiber nonwovens. In this aspect, it is preferred that the polymer is a polyolefin, more preferably high-density polyethylene. Suitable covering devices may be provided, for example, covering devices from DuPont under the trademark Tyvek®. An example of a covering device is a sealing cap.

[0058] The twenty-first embodiment of the present invention is a structure according to the present invention, preferably a structure according to any one of the first to eighteenth embodiments of the present invention, for accommodating a plurality of containers, wherein the containers are for accommodating pharmaceutical compositions, medical compositions and / or cosmetic compositions. Invention Details Features described as preferred in one category of the invention (e.g., according to the structure) are also preferred in other categories of the invention (such as uses of the structure according to the invention).

[0060] Throughout this document, the disclosed scope should preferably be understood to include both endpoints of the scope. Furthermore, each disclosure of a scope herein should preferably be understood to also disclose a preferred sub-scope that does not include one or both endpoints of the scope. For example, disclosing a scope from X1 to X2 would be understood to disclose a scope including both endpoints X1 and X2. Additionally, it should be understood that a scope including endpoint X1 but not endpoint X2, a scope not including endpoint X1 but including endpoint X2, and a scope not including both endpoints X1 and X2 are also disclosed.

[0061] Some preferred embodiments and aspects have various combinations of features as alternative examples. Where these various combinations are disclosed, they are separated by semicolons (;). For example, the list of feature combinations of preferred embodiments “a; a+b; a+c+d” discloses preferred embodiments including feature “a”, preferred embodiments including features “a” and “b”, and preferred embodiments including features “a”, “c”, and “d”.

[0062] structure The structure preferably comprises a polymer. Examples of preferred polymers include polypropylene, polyoxymethylene, polyethylene, polyethylene terephthalate, polystyrene, cyclic olefin copolymers (COC), and cyclic olefin polymers (COP). Polypropylene is particularly preferred for this structure.

[0063] The structure can be obtained using deep drawing, molding (preferably injection molding), and / or 3D printing. The structure is preferably manufactured as a single piece. A structure having a support for accommodating a container is generally referred to as a "nested device," wherein the container is subsequently used to accommodate pharmaceutical compositions, medical compositions, and / or cosmetic compositions. Here, "nested device" should preferably be understood as being used in the pharmaceutical industry.

[0064] The structure preferably includes 5 to 250, more preferably 10 to 200, even more preferably 20 to 190, further preferably 40 to 180, further preferably 60 to 180, further preferably 80 to 180, and even more preferably 100 to 160 supports.

[0065] The structure can be housed within another structure referred to as a "packaging box." Here, "packaging box" should preferably be understood as being used in the pharmaceutical industry. The structure can be sealed with a covering device (such as a "sealing cap"). Here, "sealing cap" should preferably be understood as being used in the pharmaceutical industry.

[0066] support seat The preferred holder is elongated. A first end of the holder preferably has a first opening for receiving the container. In other words, the holder is preferably adapted and arranged to insert and / or remove the container from the respective holder at the first end. The other end of the holder may be closed or may have another opening. This other opening at the other end of the holder is preferably adapted and arranged to allow a portion of the container to extend out of the holder when the container is received within it. The preferred holder includes at least one protrusion extending into the interior of the container. The preferred holder has a height conforming to at least one specification and / or standard used in the pharmaceutical industry. In a preferred embodiment of the invention, the height of the plurality of holders in the first structure is at least 17 mm, for example, 17.5 mm.

[0067] Protrusion The protrusion is preferably adapted and arranged to position the container in the holder. For example, the protrusion is adapted and arranged to position the container when it is inserted into the holder, and / or to position the container when it is removed from the holder, and / or to position the container when it is received in the holder.

[0068] The protrusion preferably comprises at least one thermoplastic material, more preferably made of at least one thermoplastic material. The protrusion can have any geometry. In a preferred aspect of the invention, one or more protrusions of the support are formed as ribs. In a preferred aspect of the invention, the protrusion is integrally formed with the sidewall of the support. In a preferred aspect of the invention, the protrusion extends in a direction substantially perpendicular to the sidewall of the support. In a preferred aspect of the invention, the protrusion and the sidewall on which the protrusion is disposed are made of the same material. In another preferred aspect of the invention, the protrusion and the sidewall on which the protrusion is disposed are made of different materials.

[0069] First planar component The first planar member is preferably arranged perpendicular to the plurality of supports. The first planar member may be arranged flush with a first end of the support of the structure. The first planar member may be arranged flush with the other end of the support of the structure. The first planar member may be arranged between the first and other ends of the support of the structure. The first planar member preferably does not include a sidewall extending 100% of the circumference of the first planar member. If the first planar member includes a sidewall extending partially around the circumference of the first planar member, it is preferred that the sidewall extends 60% or less, more preferably 45% or less, even more preferably 30% or less, and further preferably 15% or less of the circumference. The first planar member preferably does not include a sidewall extending partially around the circumference of the first planar member. The sidewall extending at least partially around the circumference of the first planar member is preferably arranged perpendicular to the first face of the first planar member.

[0070] Another planar component If the structure includes another planar component, the other planar component is preferably arranged within 10 mm, more preferably within 6 mm, even more preferably within 3 mm, and further preferably within 1 mm from the outer boundary of the first planar component.

[0071] If the structure includes another planar component, the angle between the first planar component and the other planar component is preferably in the range of 30° to 150°, more preferably 45° to 135°, even more preferably 60° to 120°, further preferably 75° to 105°, and even more preferably 85° to 95°. If the structure includes another planar component, the angle between the first planar component and the other planar component is preferably 90°.

[0072] Type 1 opening The first type of opening should preferably be understood as an opening adapted and arranged to facilitate structural movement, structural positioning, or both. Examples of structural movement include lifting the structure from another structure (e.g., a packaging box) and / or inserting the structure into another structure. Examples of structural positioning include centering the structure during the filling of a container housed within the structure.

[0073] The size of the first type of opening is preferably set to accommodate at least one or all of the following: a finger, a component of a device adapted and arranged as a moving structure, or a component of a device adapted and arranged as a positioning structure.

[0074] The preferred type of opening is at least partially defined by a boundary surface. For example, the boundary surface of the type of opening faces the opening. The boundary surface of the type of opening can be a continuous surface or a discontinuous surface. The boundary surface of the type of opening can be arranged in one or more geometric planes.

[0075] The presence of a perimeter in a first-class opening should not be construed as implying that the first-class opening has a circular cross-section. While a first-class opening may have a circular cross-section, this is not mandatory. In this disclosure, the term "perimeter" should be understood to refer to the boundary of a first-class opening of any shape.

[0076] The first type of opening can be closed or open, as long as the boundary surface extends for at least 80% of the perimeter of the first type of opening. However, it is particularly preferred that the first type of opening is closed. Here, "open" should be understood as meaning that the boundary surface of the first type of opening does not extend for 100% of the perimeter of the first type of opening. Here, "closed" should be understood as meaning that the boundary surface of the first type of opening extends for 100% of the perimeter of the first type of opening.

[0077] The first type of opening can have any shape that a person skilled in the art would consider suitable for the present invention. For example, the shape can be a semicircle, a circle, a triangle, a square, a rectangle, a polygon, a teardrop shape, an irregular shape, or a combination of at least two of the above.

[0078] The surface area of ​​the first type of opening varies by no more than 30%, more preferably no more than 20%, and even more preferably no more than 10% along the height of the first type of opening.

[0079] Examples of first-type openings are given in ISO 11040-7. This ISO 11040-7 standard should not be construed as necessarily indicating or implying limitations on first-type openings according to the invention. ISO 11040-7 is provided by reference and provides preferred values ​​for certain dimensions (e.g., first dimensions) of first-type openings according to the invention.

[0080] Part One The first part should preferably be understood as a portion of the boundary surface of the first type of opening. The first part should preferably be understood as a portion of the boundary surface of the first type of opening that is arranged closer to the edge of the first planar component than to the bracket.

[0081] The first portion and the first planar component are preferably formed as a single piece. For example, the first portion forms part of the first planar component. The first portion is preferably straight. The first portion preferably forms part of the edge of the first planar component. The surface of the first portion is preferably flush with the edge of the first planar component.

[0082] In a preferred embodiment of the invention, the height of the first portion is unstable. In another embodiment of the invention, the height of the first portion is non-uniform.

[0083] In a preferred embodiment of the invention, the maximum value of the first dimension of the first portion is equal to the maximum value of the first dimension of the first type of opening. In another preferred embodiment of the invention, the maximum value of the first dimension of the first portion is greater than the maximum value of the first dimension of the first type of opening.

[0084] container The containers mentioned herein include container walls that at least partially surround the internal volume of the container. The containers mentioned herein are designed to contain compositions such that a coating (e.g., a lubricating layer) on the inner side of the container wall (i.e., the side of the container wall facing the internal volume) and / or the inner side of the container wall can be in direct contact with the composition. Preferred containers are suitable for containing pharmaceutical compositions, medical compositions, and / or cosmetic compositions.

[0085] The first end of the container preferably includes a first orifice that allows the composition to be filled into the internal volume of the container. Preferably, the first orifice also allows the composition to be discharged from the internal volume.

[0086] The container can have any shape or form that a person skilled in the art would consider suitable for the context of this invention. A preferred container has at least one cylindrical portion. A preferred container is elongated.

[0087] The preferred container, more preferably the container wall comprises at least one glass, at least one polymer, or a combination thereof, even more preferably composed of at least one glass, at least one polymer, or a combination thereof. The glass can be any type of glass and can have any composition that a person skilled in the art would consider suitable for the context of this invention. Preferably, the glass is suitable for pharmaceutical compositions. According to the definition of glass type in Section 3.2.1 of the 7th edition of the European Pharmacopoeia 2011, the preferred glass is type I glass. Examples of preferred glasses include borosilicate glass, fused silica, and combinations thereof. Particularly preferred glasses are borosilicate glass. Examples of preferred polymers include polypropylene, polyoxymethylene, polyethylene, cyclic olefin copolymers (COC), and cyclic olefin polymers (COP). Particularly preferred herein are cyclic olefin copolymers (COC) and cyclic olefin polymers (COP).

[0088] Examples of preferred containers include cartridges, vials, ampoules, bottled vials, and syringes.

[0089] In a preferred aspect of the invention, the container (more preferably the container wall, and even more preferably the surface of the container wall facing the internal volume of the container) does not include a coating. In another preferred aspect of the invention, the container (more preferably the container wall, and even more preferably the surface of the container wall facing the internal volume of the container) includes at least one coating layer. Here, the coating should preferably be understood as a layer applied by any method known to those skilled in the pharmaceutical industry. These methods include applying the coating by spraying or wiping the coating onto the container wall, and obtaining the coating by plasma coating methods. Examples of plasma coating methods include plasma pulsed chemical vapor deposition and plasma-enhanced chemical vapor deposition.

[0090] Preferred coatings include silicone, silane, or both. In a preferred aspect of the invention, the coating is a lubricating layer. A preferred lubricating layer reduces friction when components of the container are moved within the internal volume of the container. Here, an example of a component is the plunger of a syringe, and an example of a syringe is the container. For example, the lubricating layer reduces the force required to move the plunger within the syringe barrel.

[0091] Pharmaceutical compositions and cosmetic compositions In the context of this invention, each pharmaceutical composition and each cosmetic composition is considered suitable by those skilled in the art. A pharmaceutical composition is a composition comprising at least one pharmaceutical active ingredient. A preferred pharmaceutical active ingredient is a vaccine. A cosmetic composition is a composition comprising at least one cosmetic active ingredient. A preferred cosmetic active ingredient is hyaluronic acid or botulinum toxin. Pharmaceutical and / or cosmetic compositions can be fluid or solid or both, wherein, particularly preferred herein are fluid compositions. Preferred solid compositions are granular, such as powders, various tablets, or various capsules. Another preferred pharmaceutical and / or cosmetic composition is a parenteral pharmaceutical composition, i.e., a composition administered via a parenteral route, which can be any non-enteric route. Parenteral administration can be performed, for example, by injection using a needle (typically a hypodermic needle) and syringe, or by insertion of an indwelling catheter.

[0092] size The first dimension is measured along a first direction. The second dimension is measured along a second direction, wherein the second direction is perpendicular to the first direction. The height is measured along another direction, wherein the other direction is perpendicular to both the first and second directions.

[0093] Test methods The values ​​for the first dimension, the second dimension, and the height were measured using vernier calipers. The maximum dimension of the other planar component was also measured using vernier calipers.

[0094] The average height of the boundary surface of the first type of opening is determined by measuring the height of the boundary surface at 3 mm intervals. The average height is then calculated based on these measurements. If a first portion exists, its height should also be measured, and these measurements form part of the average height calculation. However, if a first portion does not exist, height measurements are only taken at locations where the boundary surface exists.

[0095] The surface area of ​​the cross-section of the first part was determined using a 3D scanning device (such as the VL-700 model, commercially available from Keyence Corporation, Japan). The surface area of ​​the first type of opening could also be determined using a 3D scanning device.

[0096] The invention will now be described by way of non-limiting examples and exemplary embodiments. Attached Figure Description

[0097] The accompanying drawings are for illustrative purposes only and should not be construed as limiting the invention. These drawings are not to scale. Terms such as "above," "below," or similar words used in the description of the drawings should be understood in the context of the drawings.

[0098] FIG. 1A This is a schematic diagram of the structure according to the present invention, viewed from above.

[0099] FIG. 1B yes FIG. 1A A schematic diagram of the structure as seen from the side.

[0100] FIG. 2A This is a schematic diagram illustrating how to measure the size of a first-class opening.

[0101] FIG. 2B This is a diagram illustrating how to measure height.

[0102] FIG. 3A This is a schematic diagram showing a portion of the structure according to the present invention.

[0103] FIG. 3B This is a schematic diagram showing a structure that is not part of the invention.

[0104] FIG. 4A and FIG. 4B It is a variation of the structure according to the present invention.

[0105] FIG. 5A to FIG. 5C This is a schematic diagram showing an alternative shape of the first type of opening according to the same invention.

[0106] FIG. 6A to FIG. 6F This is a schematic diagram illustrating various alternative embodiments, also according to the first part of the invention.

[0107] FIG. 7A to FIG. 7C This is a schematic diagram illustrating another aspect of the invention related to the first type of opening.

[0108] FIG. 8 This is a schematic diagram showing a structure that is not part of the invention.

[0109] FIG. 9A , FIG. 9B , FIG. 10A and FIG. 10B It is a simulation diagram comparing the stress in a structure according to the present invention with the stress in a structure not according to the present invention. Detailed Implementation

[0110] The accompanying drawings are described in more detail below.

[0111] FIG. 1A and FIG. 1B FIG. 1A This is a schematic diagram of a structure 100 according to the invention, viewed from above. Structure 100 includes a plurality of supports, such as supports 1A and 1B. These supports are adapted and arranged to accommodate containers, which in turn are used to accommodate pharmaceutical compositions, medical compositions, and / or cosmetic compositions. As shown with respect to support 1A, the support includes sidewalls 4 that at least partially surround the interior 5 of the support. Structure 100 also includes a first planar member 7 surrounding the plurality of supports. The first planar member 7 has an edge 23 or boundary.

[0112] Structure 100 also includes two first-type openings 10A and 10B. The first-type openings 10A and 10B are arranged in and extend through the first planar member 7. The first-type openings 10A and 10B are adapted and arranged for inserting fingers and / or components of a device into these openings, for example, to lift structure 100 from a tub, and / or to position structure 100 during filling of a container contained within structure 100. As shown with respect to opening 10B, the first-type opening includes a boundary surface 11 that extends 100% of the circumference of the opening. It can also be seen that the first-type openings 10A and 10B are arranged symmetrically.

[0113] FIG. 1B yes FIG. 1A A schematic diagram of the structure 100 as seen from the side. FIG. 1B The first planar component 7 is shown to have a first surface 8 and another surface 9 (opposite to the first surface 8). As shown with respect to the bracket 1B, the first surface 8 faces the first end 2 of the bracket, while the other surface 9 faces the other end 3 of the bracket. The container is inserted into and removed from the bracket at the first end 2.

[0114] FIG. 2A and FIG. 2B FIG. 2A This is a schematic diagram illustrating how to measure the dimensions of a first-class opening. FIG. 2A (A portion of the structure according to the invention is shown). A first dimension 12 (e.g., length) of the first type of opening 10 is measured along a first direction 20, wherein the first direction 20 is arranged parallel to the edge 23 of the first planar member 7. A second dimension 13 (e.g., width) of the first type of opening 10 is measured along a second direction 21, wherein the second direction 21 is perpendicular to the first direction 20.

[0115] FIG. 2A It is also shown that the boundary surface 11 of the first type of opening 10 is partially formed by the first portion 14. The first portion 14 is arranged parallel to the edge 23 of the first planar member 7. A first dimension 15 (e.g., length) of the first portion 14 is measured along a first direction 20, while a second dimension 16 (e.g., width) of the first portion 14 is measured along a second direction 21.

[0116] FIG. 2A The support 1 is also shown to include protrusions 6 extending into the interior 5 of the support 1. These protrusions 6 improve the positioning of the container in the support 1.

[0117] FIG. 2B This is a diagram illustrating how to measure height. FIG. 2B The structure according to the invention, as seen from the side, is shown (for illustrative purposes, the features of the structure, such as...). FIG. 1B The features shown have been omitted. (For example...) FIG. 2B As shown, the height 17 of the first planar component, the height 18 of the first portion 14, and the height 19 of the support 1 are measured along another direction 22. Although in FIG. 2B Not shown, but the height of the boundary surface of the first type of opening is also measured along another direction 22. This other direction 22 is perpendicular to both the first direction 20 and the second direction 21, and therefore perpendicular to, for example, the first surface 8 of the first planar component. If the cross-section of the support 1 is not uniform (e.g., the support 1 is conical), the height 19 is still measured along the other direction 22 between the first end 2 and the second end 3 of the support 1.

[0118] FIG. 3A and FIG. 3B FIG. 3A This is a schematic diagram showing a portion of the structure 100 according to the present invention, while FIG. 3B This is a schematic diagram that is not part of the structure 200 according to the invention. FIG. 3AThe boundary surface 11 of the first type of opening 10 extends 100% of the circumference of the opening. Therefore, FIG. 3A The first type of opening 10 is closed. The boundary surface 11 is partially formed by the first portion 14 (located in...). FIG. 3A (between the dotted lines in the text). Similarly, as... FIG. 3A As shown, the support 1 has protrusions 6 extending into the interior of these supports 1. Furthermore, these protrusions 6 are formed as ribs extending along the height of the support 1.

[0119] FIG. 3B Structure 200 and FIG. 3A The structure is similar to 100, but has the following differences. (And...) FIG. 3A compared to, FIG. 3B The boundary surface 11 of the first type of opening 10 extends less than 80% of the circumference of the opening. This is due to the absence of a first portion. FIG. 3B The boundary surface 11 of the first type of opening 10 does not extend completely around the perimeter of the opening, therefore FIG. 3B The first type of opening in the diagram is not closed.

[0120] FIG. 3A and FIG. 3B This indicates that the structure may include another type of opening 24. Compared to the first type of opening 10, this other type of opening 24 is not adapted and arranged, for example, for lifting the structure from another structure (e.g., a packaging box). In other words, this other type of opening 24 is not adapted and arranged for inserting a finger into the opening.

[0121] FIG. 4A and FIG. 4B FIG. 4A and FIG. 4B A variation of the structure according to the invention is shown. For example... FIG. 4A As shown, the first dimension 15 of the first part 14 is larger than the first dimension 12 of the first type of opening 10. It can also be seen that the first part 14 is raised (i.e., the height of the first part 14 is greater than the height of the first planar component).

[0122] FIG. 4B A first portion 14, with a height greater than that of the first planar component 7, is also shown. The height of the first portion 14 varies between its center 25 and its end 26. The height of the first portion 14 is measured at the location where it reaches its maximum height. FIG. 4B In the middle, this is located at point 25. From FIG. 4B It can also be seen that the first dimension 15 of the first part 14 is equal to the first dimension 12 of the first type of opening 10.

[0123] The first dimension and height of the first part are independent features. For example,FIG. 4B The first dimension of the first part can also be larger than the first dimension of the first type of opening.

[0124] FIG. 5A to FIG. 5C FIG. 5A to FIG. 5C This is a schematic diagram showing an alternative shape of the first type of opening 10 according to the same invention. FIG. 5A to FIG. 5C The first type of opening 10 is viewed from above. FIG. 5A to FIG. 5C In the middle, the first part 14 is the first planar part located between the dashed lines.

[0125] FIG. 6A to FIG. 6F FIG. 6A to FIG. 6F This is a schematic diagram illustrating various alternative embodiments, also according to the first part 14 of the invention. FIG. 6A to FIG. 6E A portion of the structure as seen from the side is shown, in which the first part 14 is marked by a dashed area. FIG. 6F The first type of opening 10 is shown as viewed from above.

[0126] FIG. 6A The first part 14 is similar to, for example FIG. 3A The first part of it. FIG. 6B The first part is similar to, for example FIG. 4A The first part of it. For example... FIG. 6C to FIG. 6E As shown, the height of the first portion 14 (measured along the other direction 22) can be less than the height of the first planar member 7. Furthermore, the first portion 14 can be arranged to be flush with the first surface 8 of the first planar member 7. FIG. 6C ), can be arranged above the first face 8 ( FIG. 6D ), or it can be arranged between the first surface 8 and the other surface 9 of the first planar component 7 ( FIG. 6E ).

[0127] FIG. 6A to FIG. 6E The first portion, not shown in the diagram, also exists in alternative embodiments. For example, the height of the first portion may be less than the height of the first planar component, wherein the first portion is arranged to be flush with the other side of the first planar component (i.e., with). FIG. 6C Conversely), the first part can also be arranged similarly to... FIG. 6D The first part is shown, but the first part is arranged below the other side of the first planar component.

[0128] FIG. 6A to FIG. 6E Each of the first type of openings 10 is closed, meaning the boundary surface extends 100% of the circumference of the opening. Note that the first portion 14 forms part of the boundary surface, for example in... FIG. 6D As can be seen, the boundary surface 11 can be arranged in different geometric planes.FIG. 6D In this configuration, the first portion 14 is arranged above the rest of the boundary surface 11. FIG. 6D The boundary surface 11 in the middle is also discontinuous.

[0129] FIG. 6A to FIG. 6E The diagram also illustrates how the maximum height of the boundary surface of the first type of opening should be measured. It should be noted that the surface of the first portion 14 facing the first type of opening forms part of the boundary surface. FIG. 6A In this system, the height of the boundary surface is uniform, and the maximum height can be measured at any location on the boundary surface (including at the first part 14). FIG. 6B In this case, the height of the first section 14 is greater than the height measured at other locations on the boundary surface. Therefore, the maximum height of the boundary surface is measured at the first section 14. FIG. 6C to FIG. 6E In this diagram, the height of the first part 14 is less than the height of the other parts of the boundary surface. Therefore, the maximum height of the boundary surface is not measured at the first part 14. As shown in the figure, the maximum height of the boundary surface should therefore be measured at the location where the height is at its maximum.

[0130] FIG. 6F The first type of opening 10 is shown, wherein the first portion 14 is not arranged flush with the edge 23 of the first planar member 7. FIG. 6F The first part 14 is arranged parallel to the edge 23. FIG. 6F The first part 14 shown also exists in alternative embodiments according to the invention. For example, FIG. 6F The first part 14 can be arranged at a certain angle to the edge 23. FIG. 6F The combinations of the embodiments shown can also be combined with, for example, FIG. 6A to FIG. 6E The embodiments shown are combined.

[0131] FIG. 7A to FIG. 7C FIG. 7A to FIG. 7C This is a schematic diagram illustrating another aspect of the invention related to the first type of opening. FIG. 7A to FIG. 7C The first type of opening is shown as viewed from above.

[0132] FIG. 7A The perimeter 27 of the first type of closed opening 10 is shown, which is indicated by a dashed line. FIG. 7A Opening 10 in the middle and FIG. 3A (Similar to the opening 10 shown). It can be seen that the perimeter 27 extends around the first type of opening 10. FIG. 7B The first type of unclosed opening 10 is shown (e.g.) FIG. 3B (As shown). For FIG. 7B The first type of opening 10 is defined by drawing an imaginary line 28 along the edge 23 of the first planar component, such as...FIG. 7B As shown. Then the imaginary line 28 is considered as part of the perimeter 27 of the first type of opening 10.

[0133] FIG. 7C The surface area 29 of the first type of opening 10 is shown. The surface area 29 is shown by the shaded area. The shaded area also shows the shape 29 of the first type of opening 10. FIG. 7C The surface area of ​​the cross-section of the first portion 14 is also shown. This cross-section should be located at position 30, indicated by the dashed line. The dashed line is perpendicular to the edge 23 of the first planar component 7.

[0134] FIG. 8 FIG. 8 This is a schematic diagram showing a structure 200 that is not part of the invention. (As shown in...) FIG. 8 As can be seen, structure 200 has a first type of opening 31. Compared with the first type of opening 10, the first type of opening 31 is used to insert components of the device to lift the structure. FIG. 8 The diagram shows a first type of opening 31 partially surrounded by an opening wall 32, which also forms the boundary surface of the opening 31. The opening wall 32 protrudes from the first planar member 7. The height of the boundary surface of the first type of opening 31 should be understood to include the height of the opening wall 32 (the height of which is also measured in another direction). In other words, FIG. 8 The maximum height of the boundary surface of the first type of opening 31 is greater than the height of the boundary surface of a similar first type of opening without an opening wall 32.

[0135] FIG. 8 Another planar component 33 protruding from the first planar component 7 is also shown. FIG. 8 Another planar component 33 forms a sidewall that extends 100% of the circumference of the first planar component 7. FIG. 8 In this context, the maximum dimension of the other planar component 33 is measured along one or more directions parallel to the first surface 8 of the first planar component 7. The maximum dimension of the other planar component 33 is not necessarily the dimension (e.g., length) of the other planar component 33 measured along a single direction. Instead, in... FIG. 8 In this context, the maximum dimension of the other planar component 33 is the total length of said component 33 measured around the perimeter of the first planar component 7. If the structure has another planar component, the maximum height of the first planar component should be understood to include the height of the other planar component (whose height is also measured in another direction). In other words, in FIG. 8 In the case of the first planar component 7, the maximum height is greater than the height of the first planar component with a similar structure that does not have another planar component 33.

[0136] if FIG. 3AIf the opening 31 does not extend through the first planar member 7, but is formed, for example, by a sidewall 32 arranged on the first planar member 7 such that the planar member forms the bottom surface of the opening 31, then this would be an example of a cavity.

[0137] Example The invention is further illustrated by examples. The invention is not limited to these examples.

[0138] Example 1 In Example 1, three different types of nesting devices (structures) are provided for accommodating containers for pharmaceutical compositions, medical compositions, and / or cosmetic compositions.

[0139] Example 1.1: A nesting device according to the present invention, the nesting device comprising a first type of closed opening, such as... FIG. 3B As shown.

[0140] Example 1.2: A nesting device not according to the invention, the nesting device comprising a first type of open opening, such as... FIG. 8 As shown.

[0141] Example 1.3: A nesting device not according to the invention, the nesting device comprising a first type of opening having sidewalls, such as... Example 2 As shown.

[0142] Table 1 shows a comparison of the nested devices in Examples 1.1 to 1.3.

[0143] Table 1 The technical effects shown in Table 1 are as follows: - Deviation from the intended shape of the nested device: The degree to which the nested device deviates from its intended shape during the production or sterilization process. "-" indicates a small deviation, and "+" indicates a large deviation. The goal is to reduce this deviation from the intended shape.

[0144] Deformation of the nested device under load: The degree of deformation of the nested device when subjected to load and / or stress. "-" indicates small deformation, and "+" indicates large deformation. The goal is to reduce the deformation of the nested device.

[0145] Material required for nested devices: The amount of material required to produce a nested device that can withstand a certain stress without deformation. "-" indicates less material is required, and "+" indicates more material is required. The goal is to reduce the amount of material required.

[0146] Manipulation ease of nested devices: The ease with which the nested devices are manipulated (including removing them from the packaging), and the ease with which they can be accessed via a robotic suction tool into the first type of opening / cavity. "-" indicates decreased manipulation ease, and "+" indicates high manipulation ease. Improved manipulation is desired.

[0147] Long-term dimensional stability: Nested devices undergo material creep under load (e.g., due to containers being housed within them). Prolonged (e.g., more than one year) use and storage of nested devices leads to deformation. A "+" indicates good dimensional stability (i.e., minimal deformation), while a "-" indicates poor dimensional stability (i.e., significant deformation). Improving dimensional stability is desired.

[0148] Water accumulation during the sterilization process of nested devices: The amount of water accumulated in the nested device during steam sterilization. For example, nested devices with sidewalls may cause water accumulation on the first planar component, and deformation of the nested device may also lead to water accumulation. "-" indicates less water accumulation, and "+" indicates more water accumulation. Minimizing water accumulation is desired.

[0149] Particle formation during transport within the packaging box: The number of particles formed during the storage and / or transport of the nesting device within the packaging box. This particle formation is due to, for example, friction between the nesting device and the surface of the packaging box (e.g., the surface of the packaging box on which the nesting device is located). "+" indicates more particles formed, and "-" indicates fewer particles formed. It is desirable to reduce particle formation.

[0150] FIG. 3A In Example 2, the deformation of the nested device is studied using finite element simulation. The support of the nested device has a protrusion extending into the interior of the support (e.g., as shown in the image). FIG. 3B and FIG. 3A (As shown). These protrusions are in the form of ribs, which extend along the height of the support. In Example 2, the heights of these ribs are different.

[0151] The nesting device having a first-type closed opening is a nesting device according to the invention, and as follows: FIG. 3B As shown. Nesting devices with a first type of open opening are not nesting devices according to the invention, and as... FIG. 9A As shown in the image.

[0152] The results of Example 2 are shown in Table 2.

[0153] Table 2 The technical effects shown in Table 2 are as follows: - Center deflection: The deformed nested device forms a depression at the center of the nested device. The deflection is the depth of this depression.

[0154] - Von Mises stress at the center: Stress measured at the center of the nested device.

[0155] Von Mises stress at a first-class opening: the stress measured at a first-class opening.

[0156] Simulation results in FIG. 9B , FIG. 10A , FIG. 10B and FIG. 9A As shown in the image. FIG. 10A and FIG. 9B Structure 100 in the present invention is a structure according to the present invention, and FIG. 10B and FIG. 9A Structure 200 in the figures is not a structure according to the invention. The brighter areas in these structures represent regions with larger von Mises values ​​(i.e., larger stresses). As can be seen in these figures, a depression forms at the center of the structure. Simulation results show that the first type of closed opening significantly reduces structural deformation compared to an open opening.

[0157] contrast FIG. 9B and FIG. 10A It can be seen that the stress at the center of structure 100 is lower than that at the center of structure 200. The depression formed at the center of structure 100 is also shallower than that formed in structure 200. FIG. 10B and FIG. 9A Structures 100 and 200 in the model also show similar results (however, compared to...). FIG. 9B and FIG. 10A Compared to the structure in, FIG. 10B and ​ (The structural deformation is relatively small).

[0158] List of reference numerals 1. Support 2. The first end of the support 3. The other end of the support 4. Side wall of the support 5. The interior of the support 6. Protrusion of the support 7 First planar component 8 First surface of the first planar component 9. The other side of the first planar component 10 First type of opening 11 Boundary surfaces of first-class openings 12 First dimension of the first type of opening 13 The second dimension of the first type of opening 14 Part 1 15 First dimension of the first part 16 The second dimension of the first part 17. Height of the first planar component 18. Height of Part One 19. Height of the support 20 First Direction 21 Second Direction 22. Another direction 23 The edge of the first planar component 24 Another type of opening 25 The Center of Part One 26 The end of the first part 27. Perimeter of the first type of opening 28 Imaginary lines 29. Surface area / shape of first-class openings 30. Position of the cross-section 31 First type of opening 32 Opening wall 33 Another planar component.

Claims

1. A structure comprising: a. A plurality of brackets, wherein each of the plurality of brackets: i. Adapted and arranged to accommodate containers; ii. The height must be at least 10mm; iii. Having a first end and an other end opposite to the first end; iv. Includes sidewalls that at least partially surround the interior of the support; b. A first planar component, the first planar component at least partially surrounding the plurality of supports, wherein the first planar component: i. Includes a first surface and a surface opposite to the first surface, wherein, A. The first surface faces the first end of the plurality of supports, and B. The other side faces the other end of the plurality of supports; ii. Has a maximum height of less than or equal to 3mm; iii. Includes at least two first-class openings, wherein the following applies to each of the at least two first-class openings: A. Extending through the first planar component, and B. Includes a boundary surface that extends around at least 80% of the perimeter of the corresponding first-class opening.

2. The structure according to claim 1, wherein, For each of the at least two first-class openings, the boundary surface extends 100% of the circumference of the corresponding first-class opening.

3. The structure according to any one of the preceding claims, wherein, One of the following applies: i. The maximum dimension of any additional planar component protruding from the first planar component is less than 10 cm; or ii. The structure does not include any additional planar components protruding from the first planar component.

4. The structure according to any one of the preceding claims, wherein, The surface area of ​​each of the at least two first-type openings is 100 mm. 2 Up to 550mm 2 Within the range.

5. The structure according to any one of the preceding claims, wherein, Each of the at least two first-type openings has at least one or all of the following characteristics: a. The maximum value of the first dimension is in the range of 10mm to 40mm; b. The maximum value of the second dimension is in the range of 10mm to 50mm.

6. The structure according to any one of the preceding claims, wherein, At least one or all of the following applies: a. The average height of the boundary surface of each of the at least two first-type openings is less than 14 mm; b. The maximum height of the boundary surface of each of the at least two first-class openings is less than 14 mm.

7. The structure according to any one of the preceding claims, wherein, The boundary surface is at least partially formed by a first portion, wherein the maximum value of the second dimension of the first portion is in the range of 0.5 mm to 11 mm.

8. The structure according to any one of the preceding claims, wherein, The boundary surface is at least partially formed by a first portion, wherein the surface area of ​​the cross-section of the first portion is 0.1 mm. 2 Up to 40mm 2 Within the range, wherein the cross-section satisfies: I. Perpendicular to the edge of the first planar component, and II. Formed at the location where the second dimension of the first part, for example, the width, has a minimum value.

9. The structure according to any one of claims 7 to 8, wherein, The first portion is arranged parallel to a portion of the edge of the first planar component.

10. The structure according to any one of claims 7 to 9, wherein, One of the following applies: a. The maximum height of the first portion is equal to or greater than the maximum height of the first planar component; or b. The maximum height of the first part is equal to or less than the maximum height of the first planar component.

11. The structure according to any one of claims 7 to 10, wherein, The maximum height of the first part is xH ,in, H The maximum height of the first planar component. x In the range of 0.3 to 10.

12. The structure according to any one of claims 7 to 11, wherein, The maximum height of the first part is in the range of 0.4 mm to 14 mm.

13. The structure according to any one of claims 7 to 12, wherein, At least one or all of the following applies: a. The maximum value of the first dimension of the first portion is equal to or greater than the maximum value of the first dimensions of the at least two first-type openings; b. The maximum value of the first dimension of the first part is in the range of 3mm to 70mm.

14. A method for transporting multiple containers, the method comprising the steps of: a. To provide a structure according to any one of the preceding claims; b. The structure receives multiple containers; c. Preferably, the structure and the plurality of containers are transported from the first location to another location.

15. The use of the structure according to any one of claims 1 to 13 for accommodating a plurality of containers, wherein, The container is used to contain pharmaceutical compositions, medical compositions, and / or cosmetic compositions.

Images