Gel film patch containing endogenous crystal patterns and preparation method of gel film patch

Abstract

The invention relates to the technical field of cosmetics, and particularly discloses a gel mask patch containing endogenous crystal patterns and a preparation method thereof.The gel mask patch comprises a matrix gel layer and an endogenous crystal structure, and a matrix is composed of 60-80% of water, 1-3% of gelling agent, 1-10% of polyhydric alcohol and 5-18% of active matter; the active matter is a eutectic system of trehalose / mannitol and glycine / taurine, and snowflake-shaped crystals protruding out of the surface by 0.1-0.3 mm are formed. During preparation, cold air nucleation is performed at 20-30 DEG C, then shock cooling directional growth is performed at 5-10 DEG C, and finally low-temperature drying and curing are performed at 40-45 DEG C. According to the invention, active matters beneficial to skin are added, and temperature change in a hydrogel production process is utilized, so that the active matters are condensed from a dissolved state and are separated out by self-crystallization, a snowflake-shaped pattern effect is formed, physical embossing or injection molding is not depended on, and the appearance of the product changes randomly and is rich and diversified; when the mask is applied, the branched crystals protrude out of the surface of the mask body to form physical attachment with the skin, gliding is prevented when the mask is used, and the functions of physical massage and physiological improvement on the skin are achieved.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, and specifically discloses a gel film patch containing endogenous crystal patterns and its preparation method. Background Technology

[0002] Hydrogel patches utilize the water-fixing and releasing properties of plant polysaccharides such as carrageenan to provide a cooling, moisturizing, and hydrating effect on the skin. Currently, commercially available hydrogel products primarily use macromolecular polysaccharides such as carrageenan, agar, carob gum, and cellulose, along with a certain amount of polyols and purified water. These are dissolved at high temperatures, cooled and solidified, and then cut into the desired product shape. In terms of appearance, they are mostly transparent, come in various colors, or have regular patterns. Their main function is to release water to provide cooling, hydration, and moisturizing. The appearance of these hydrogel products is relatively uniform; besides the inherent transparency of the hydrogel itself, differences in appearance are achieved by adding pigments, opacifiers (titanium dioxide, kaolin, etc.), physical particles (insoluble particles, plant powders), or through physical embossing techniques. Hydrogel products have a jelly-like consistency, and due to their tendency to naturally release water upon standing, they lack physical adhesion points to the skin, making them prone to slipping and affecting the user experience. Summary of the Invention

[0003] In view of the above-mentioned problems of the existing technology, the purpose of the present invention is to provide a gel film patch that forms a three-dimensional pattern through endogenous eutectic. By utilizing the temperature changes in the hydrogel production process, the active material is condensed from the dissolved state and crystallized out, thus solving the problems of monotonous appearance, slippage of the patch, and slow release of the active material.

[0004] The objective of this invention can be achieved through the following technical solutions: 1. A gel film patch containing an endogenous crystalline pattern, characterized in that it comprises: a matrix gel layer and an endogenous crystalline structure, wherein the matrix gel layer is composed of the following components in weight percentage: Purified water 60-80% gelling agent 1-3% Polyols 1-10% Active ingredient 5-18% Preservative 0.1-0.5% Fragrance 0.01-0.1%; The endogenous crystalline structure is distributed on the surface and inside of the matrix gel layer, and the endogenous crystalline structure includes: (a) A eutectic system in which at least one of trehalose or mannitol is formed with at least one of glycine or taurine; (b) Crystals protrude 0.1-0.3 mm from the matrix surface, with a density of 5-20 crystals / cm³. 2 ; (c) The crystal morphology is a randomly distributed snowflake-like or dendritic structure.

[0005] As a further preferred embodiment of the present invention, the active ingredient is composed of a first component and a second component, wherein: The first component is trehalose or mannitol, accounting for 40-70% of the total mass of the active ingredients; The second component is glycine or taurine, accounting for 30-60% of the total mass of the active ingredient.

[0006] As a further preferred technical solution of the present invention, the gelling agent is at least one of carrageenan, konjac gum, and carob gum, and the proportion of carrageenan is not less than 50% when the gelling agent is compounded.

[0007] As a further preferred technical solution of the present invention, the polyol is at least one of glycerol, propylene glycol, and hexanediol, and the proportion of glycerol in the polyol is ≥70%.

[0008] As a further preferred technical solution of the present invention, the method for preparing a gel film patch containing endogenous crystalline patterns includes the following steps: S1. Heat purified water to 50-60℃, add the premix of gelling agent and polyol, and stir and disperse at 800-1200 rpm; S2. Heat to 80-85℃ and hold for 10-15 minutes to form a homogeneous adhesive solution; S3. Add the active ingredient, stir for 10-15 minutes until completely dissolved, and keep the temperature at 80-85℃ for 10 minutes. S4. Add flavoring and preservatives, stir well, and then discharge. S5. Pour the adhesive into a flat mold, allow the material to cool naturally to form a thin sheet, and repeat the process in sequence: First stage cooling: Treat the surface with cold air at 20-30℃ in the cooling tunnel for 2-3 minutes, and hold for 2 minutes to allow the surface crystals to precipitate to the required length; The second stage of rapid cooling: the crystals are solidified by maintaining a low temperature drying tunnel at 40℃-45℃ for 5 minutes. S6. Cut and shape and package.

[0009] As a further preferred technical solution of the present invention, the active ingredient is added in steps: first, trehalose or mannitol is added, stirred and dissolved, and then glycine or taurine is added.

[0010] As a further preferred technical solution of the present invention, a rapid cooling stage can be added between the first stage of cooling and the second stage of curing, wherein the rapid cooling stage is a low temperature treatment of 5-10℃ for 30-60s.

[0011] As a further preferred technical solution of the present invention, the temperature difference between the first stage cooling and the second stage rapid cooling is ≥15℃, and the transition time between the two stages is ≤10s.

[0012] As described above, the method for preparing a low-gas-production, easily moldable thermosetting polyimide resin provided by the present invention has the following beneficial effects: 1. This invention discloses a gel film patch with an endogenous crystalline pattern, utilizing a eutectic system formed by trehalose / mannitol and glycine / taurine under a specific temperature gradient. The sugar alcohols provide the dendritic crystalline framework, while amino acids fill the lattice gaps to enhance structural strength. The protruding crystals form microscopic anchor points, independent of physical embossing or injection molding, resulting in a randomly varied and diverse product appearance. During application, the branched crystals protrude 0.1-0.3 mm from the film surface, forming a physical adhesion with the skin and preventing slippage.

[0013] 2. This invention discloses a gel film patch containing endogenous crystalline patterns and its preparation method. Compared with the prior art, it adds a higher concentration of skin-beneficial active ingredients. By utilizing the temperature variations in the hydrogel production process, the active ingredients are condensed from a dissolved state and crystallized out. Three-stage temperature control achieves directional crystal growth, forming a random snowflake-like pattern effect. The product appearance varies randomly and is rich and diverse. It not only prevents slippage during use but also provides physical massage and physiological improvement for the skin.

[0014] Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0015] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0016] Figure 1 This is a finished product image of a gel film patch containing an endogenous crystal pattern, as per this invention application.

[0017] Figure 2 A finished product image of a regular hydrogel film. Detailed Implementation

[0018] The following specific embodiments illustrate the implementation of the present invention. Those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification.

[0019] It should be understood that the structures, proportions, sizes, etc., depicted in the accompanying drawings of this specification are merely for illustrative purposes to aid those skilled in the art and are not intended to limit the scope of the invention. Therefore, they have no substantial technical significance. Any modifications to the structure, changes in proportions, or adjustments to size, without affecting the effectiveness and purpose of the invention, should still fall within the scope of the technical content disclosed in this invention. Furthermore, the terms such as "upper," "lower," "left," "right," "middle," and "one" used in this specification are merely for clarity and are not intended to limit the scope of the invention. Changes or adjustments to their relative relationships, without substantially altering the technical content, should also be considered within the scope of the invention. Specific structures can be described with reference to the accompanying drawings of the patent application.

[0020] This invention provides a gel film with an endogenous crystalline pattern, comprising a base gel layer and an endogenous crystalline structure, wherein the base gel layer is composed of the following components by weight percentage: Purified water 60-80% gelling agent 1-3% Polyols 1-10% Active ingredient 5-18% Preservative 0.1-0.5% Fragrance 0.01-0.1%; The endogenous crystalline structure is distributed on the surface and inside the matrix gel layer, and the endogenous crystalline structure satisfies: (a) A eutectic system in which at least one of trehalose or mannitol is formed with at least one of glycine or taurine; (b) Crystals protrude 0.1-0.3 mm from the matrix surface, with a density of 5-20 crystals / cm³. 2 ; (c) The crystal morphology is a randomly distributed snowflake-like or dendritic structure.

[0021] The active ingredient comprises 40-70% trehalose or mannitol by mass of the total active ingredient, and 30-60% glycine or taurine.

[0022] The gelling agent is at least one of carrageenan, konjac gum, and carob gum, and the mass percentage of carrageenan in the compound system is ≥50%.

[0023] The polyol is at least one of glycerol, propylene glycol, and hexanediol, and glycerol accounts for more than 70% of the total mass of the polyol.

[0024] The preparation method of the gel film patch includes the following steps: S1. Heat purified water to 50-60℃, add the premix of gelling agent and polyol, and stir and disperse at 800-1200 rpm; S2. Heat to 80-85℃ and hold for 10-15 minutes to form a homogeneous adhesive solution; S3. Add the active ingredient, stir for 10-15 minutes until completely dissolved, and keep the temperature at 80-85℃ for 10 minutes. S4. Add flavoring and preservatives, stir well, and then discharge. S5. Pour the adhesive into a flat mold, allow the material to cool naturally to form a thin sheet, and repeat the process in sequence: First stage cooling: Treat the surface with cold air at 20-30℃ in the cooling tunnel for 2-3 minutes, and hold for 2 minutes to allow the surface crystals to precipitate to the required length; The second stage of rapid cooling: the crystals are solidified by maintaining a low temperature drying tunnel at 40℃-45℃ for 5 minutes. S6. Cut and shape and package.

[0025] In step S3, the active ingredients are added in stages: first, trehalose or mannitol is added, and after dissolving, glycine or taurine is added.

[0026] A rapid cooling stage can be added between the first stage of cooling and the second stage of curing. The rapid cooling stage is a low-temperature treatment at 5-10℃ for 30-60 seconds.

[0027] The temperature difference between the first stage of cooling and the second stage of rapid cooling is ≥15℃, and the transition time between the two stages is ≤10s.

[0028] Example 1 Formula: 72% purified water, 1.5% konjac gum, 0.5% carrageenan, 6% glycerin, 9% trehalose, 6% glycine, 0.3% preservative, and 0.05% flavoring.

[0029] Process: Add gelling agent / glycerin premix to water at 55℃ and disperse at 1000 rpm. Keep warm at 83℃ for 12 minutes Cool to 76℃, add active ingredients (trehalose first, then glycine), and incubate for 12 minutes. After casting, the first stage involves cooling the surface crystals to the required length by 25°C cold air in a cooling tunnel for 2.5 minutes. Then, the crystals are cooled in a semi-sealed freezing tunnel at 7±0.5°C for 45±3 seconds with a temperature change rate ≥5°C / s. In the third stage, the crystals are dried in a low-temperature drying tunnel at 42°C for 5 minutes to solidify the crystals. The humidity of the tunnel cavity is 10±2%RH.

[0030] result: Crystal height 0.25±0.03mm, density 12 crystals / cm³2 The coefficient of friction μ=0.38 (no slippage on a 45° inclined plane).

[0031] Comparative Example variable result 4% of total active ingredients No crystallization Cancel the quenching step <![CDATA[Crystalline density ≤ 3 per cm 2 > Glycine replaced with sodium chloride Irregular crystal morphology and easy to break This product is suitable for facial care masks, eye masks, neck masks and other beauty products. The crystalline structure generates 0.5kPa micro-pressure when applied, which promotes the absorption of active ingredients (in vitro transdermal experiments show a 22% increase in permeability).

[0032] Example 2 Preparation process Step 1: Preparation of the gel base Add 70 kg of purified water (resistivity ≥ 15 MΩ·cm) to a 316L stainless steel emulsifying pot. After heating to 55±1℃, add 1.2kg of premixed carrageenan, 0.8kg of konjac gum, and 6.3kg of glycerin. Disperse at 1000 rpm for 10 min (paddle diameter / pot diameter ratio = 0.6).

[0033] Step 2: Dissolve at high temperature The temperature was increased to 83±0.5℃ at 2℃ / min, held for 12min, and the stirring speed was reduced to 300rpm. The sample was then tested. The transmittance of the adhesive solution was ≥90% (550nm, 1cm cuvette) to meet the standard.

[0034] Step 3: Loading of active ingredients Cool down to 76±0.3℃ (cooling rate 1.5℃ / min).

[0035] Add in steps: a) Add 8.5 kg of trehalose and stir at 300 rpm for 5 minutes until clear. b) Add 5.5 kg of glycine, keep warm and stir for 10 min (dissolution endpoint conductivity ≤ 5 μS / cm).

[0036] Step 4: Mold Pre-treatment After the PET mold is heated to 120°C to soften it, it is adsorbed and formed using a negative pressure mold.

[0037] Step 5: Gradient crystallization The above-mentioned mixture containing active ingredients is poured into a polypropylene mold, and then treated with cold air at 25°C in a cooling tunnel for 150 seconds to allow surface crystals to precipitate to the required length. After being dried in a low-temperature drying tunnel for 5 minutes with hot air at 42°C, the crystals are solidified. The humidity of the tunnel cavity is 10±2%RH.

[0038] Step 6: Post-processing Cut using a stamping die set, then use a material with an oxygen permeability ≤0.5cm.3 / m 2 • 24-hour aluminum-plastic composite film packaging.

[0039] The dendritic structure parameters are as follows: Example 3 Anti-slip effect verification Formula and process: Same as Example 2 Verification method: 1. Crystal structure characterization: Laser confocal microscopy was used to measure crystal height (0.12-0.18 mm). Image analysis software calculates coverage (28±3%), see attached figure. Figure 1 It shows a random dendritic crystal distribution.

[0040] 2. Anti-slip test: 45° Inclined Surface Application Experiment: Control Group (with attached) Figure 2 (Ordinary hydrogels without crystals) slide down within 10 seconds; the product of this invention remains displacement for 30 minutes. Friction coefficient test: The crystals increased the static friction coefficient between the film patch and skin from 0.35 to 0.52. Conclusion: Dendritic crystals form a physical anchoring structure, which significantly improves adhesion.

[0041] Example 4 Dual-effect skin improvement verification Formula and process: Same as Example 2 Test method: 30 subjects were selected for each test, and the patch was applied for 15 minutes daily for 7 days to test its efficacy on human bodies. The crystal massage technique of this invention promotes microcirculation. Thermal imaging showed that the skin temperature increased by 2.3°C after application. In addition, glycine / trehalose continued to penetrate through the crystallization-dissolution process, resulting in significant physiological improvement of the skin of the test subjects.

[0042] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the invention can be implemented in other specific forms without departing from its spirit or essential characteristics. Therefore, the embodiments should be considered in all respects as exemplary and non-limiting, and the scope of the invention is defined by the appended claims rather than the foregoing description. Thus, all variations falling within the meaning and scope of equivalents of the claims are intended to be included within the present invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

Claims

1. A gel film patch containing an endogenous crystalline pattern, characterized in that, include: The matrix gel layer and the endogenous crystalline structure, wherein the matrix gel layer is composed of the following components by weight percentage: Purified water 60-80% gelling agent 1-3% Polyols 1-10% Active ingredient 5-18% Preservative 0.1-0.5% Fragrance 0.01-0.1%; The endogenous crystalline structure is distributed on the surface and inside of the matrix gel layer, and the endogenous crystalline structure includes: (a) A eutectic system in which at least one of trehalose or mannitol is formed with at least one of glycine or taurine; (b) Crystals protrude 0.1-0.3 mm from the matrix surface, with a density of 5-20 crystals / cm³. 2 ; (c) The crystal morphology is a randomly distributed snowflake-like or dendritic structure.

2. The gel film patch with endogenous crystalline patterns according to claim 1, characterized in that, The active ingredient is composed of a first component and a second component, wherein: The first component is trehalose or mannitol, accounting for 40-70% of the total mass of the active ingredients; The second component is glycine or taurine, accounting for 30-60% of the total mass of the active ingredient.

3. The gel film patch containing endogenous crystalline patterns according to claim 1, characterized in that, The gelling agent is at least one of carrageenan, konjac gum, and carob gum, and the proportion of carrageenan is not less than 50% when the gelling agent is compounded.

4. The gel film patch containing endogenous crystalline patterns according to claim 1, characterized in that, The polyol is at least one of glycerol, propylene glycol, and hexanediol, and the proportion of glycerol in the polyol is ≥70%.

5. A method for preparing a gel film patch containing an endogenous crystalline pattern as described in any one of claims 1-4, characterized in that, Includes the following steps: S1. Heat purified water to 50-60℃, add the premix of gelling agent and polyol, and stir and disperse at 800-1200 rpm; S2. Heat to 80-85℃ and hold for 10-15 minutes to form a homogeneous adhesive solution; S3. Add the active ingredient, stir for 10-15 minutes until completely dissolved, and keep the temperature at 80-85℃ for 10 minutes. S4. Add flavoring and preservatives, stir well, and then discharge. S5. Pour the adhesive into a flat mold, allow the material to cool naturally to form a thin sheet, and repeat the process in sequence: First stage cooling: Treat the surface with cold air at 20-30℃ in the cooling tunnel for 2-3 minutes, and hold for 2 minutes to allow the surface crystals to precipitate to the required length; Second stage curing: The crystals are cured by maintaining a low temperature drying tunnel at 40℃-45℃ for 5 minutes. S6. Cut and shape and package.

6. The method for preparing a gel film patch containing endogenous crystalline patterns according to claim 5, characterized in that, The active ingredient is added in steps: first, trehalose or mannitol is added, stirred and dissolved, and then glycine or taurine is added.

7. The method for preparing a gel film patch containing endogenous crystalline patterns according to claim 5, characterized in that, A rapid cooling stage is added between the first stage of cooling and the second stage of curing. The rapid cooling stage is a low-temperature treatment at 5-10℃ for 30-60 seconds.

8. The method for preparing a gel film patch containing endogenous crystalline patterns according to claim 7, characterized in that, The temperature difference between the first stage of cooling and the rapid cooling stage is ≥15℃, and the transition time between the two stages is ≤10s.

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