Temperature measuring device for general biological analysis instrument and measuring method thereof

Abstract

The invention discloses a temperature measuring device for a general biological analysis instrument and a measuring method of the temperature measuring device, and particularly relates to the technical field of temperature measurement of biological analysis instruments, the temperature measuring device mainly comprises a measuring base, and one side of the outer wall of the measuring base is fixedly connected with a linkage switching frame plate; three guide frame plates are arranged on the outer wall of the measuring base and located on one side of the linkage switching frame plate, and a linkage separation mechanism is connected to the interior of the linkage switching frame plate; the linkage switching mechanism comprises a linkage screw rod connected to the interior of the linkage switching frame plate, and the outer wall of the linkage screw rod is provided with a threaded sleeving supporting block in sliding connection with the linkage switching frame plate. A linkage separation mechanism is adopted, a new standby temperature sensor can be quickly switched to continuously measure the temperature of a biological material which is not analyzed in a closed manner without waiting for maintenance by professional personnel once the biological material is damaged, data generated by analysis cannot be influenced by external other temperature pollution, the influence on the data detection accuracy is avoided, and the detection efficiency is improved. And the data detection accuracy is effectively improved.

Description

Technical Field

[0001] This invention relates to the field of temperature measurement technology for biological analysis instruments, and more specifically, to a temperature measuring device and method for general biological analysis instruments. Background Technology

[0002] General-purpose bioanalytical instruments include PCR instruments, which are used for DNA or RNA amplification. PCR achieves rapid amplification of specific DNA or RNA fragments by denaturing, annealing, and extending them in a thermal environment. Therefore, PCR instruments require a precise temperature control system to ensure the accuracy and reliability of experimental results. During PCR experiments, temperature variations and stability directly affect the results. Unstable temperature control may lead to insufficient denaturation, inadequate annealing, or incorrect extension of DNA or RNA, thus affecting the accuracy and reproducibility of the experimental results. Therefore, temperature measurement devices in general-purpose bioanalytical instruments play a particularly important role in temperature measurement.

[0003] Patent publication number CN216386045U discloses a temperature measuring device for a general-purpose bioanalytical instrument. This patent primarily addresses the problem of commonly used temperature measuring modules, such as the STA-D series 18B20 data acquisition module. In practice, the interface of the STA-D series 18B20 data acquisition module is typically directly connected to the corresponding bioanalytical instrument, resulting in inconsistent module interface heights. This necessitates using external supports to elevate the temperature control device for connection, significantly reducing the flexibility of the equipment. This patent addresses this by allowing for flexible height adjustment via a lifting mechanism. Compared to traditional lifting mechanisms, the device offers higher height adjustment accuracy, and a single motor enables both height and heat dissipation adjustments, greatly reducing production costs. However, this temperature measuring device also has the following drawbacks.

[0004] In the use of general-purpose bioanalytical instruments, a temperature measuring device is required to monitor the temperature in real time during the bioanalysis process. However, if a single temperature sensor is damaged, it requires waiting for professional personnel to repair it. In this case, the temperature of the biological material that has not yet been analyzed cannot be measured. After opening the cover of the general-purpose bioanalytical instrument, the range of errors in the analyzed data is large, which affects the accuracy of the data detection. Therefore, it is necessary to provide a temperature measuring device and its measurement method for general-purpose bioanalytical instruments. Summary of the Invention

[0005] To overcome the above-mentioned deficiencies of the prior art, the present invention provides a temperature measuring device and a measuring method for a general-purpose biological analysis instrument.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a temperature measuring device for a general biological analysis instrument, comprising a measuring base, a linkage switching frame plate fixedly connected to one side of the outer wall of the measuring base, three guide frames provided on the outer wall of the measuring base and located on one side of the linkage switching frame plate, and a linkage disengagement mechanism connected inside the linkage switching frame plate.

[0007] The linkage switching mechanism includes a linkage screw connected inside the linkage switching frame plate, and the outer wall of the linkage screw is provided with a threaded sleeve support block that is slidably connected to the linkage switching frame plate. One end of the linkage screw extends to the outside of the linkage switching frame plate and is coaxially driven by a reduction drive motor. The top end of the threaded sleeve support block is fixedly connected to a reduction angle drive motor. An arc-shaped guide groove plate with a circular arc cross-section is welded to one side of the outer wall of the reduction angle drive motor, and an arc-shaped sliding strip is slidably connected inside the arc-shaped guide groove plate. A linkage reduction motor is fixedly connected to one end of the arc-shaped sliding strip. The output ends of the reduction angle drive motor and the linkage reduction motor are both connected to a rotating shaft. A switching component is installed at the top end of the rotating shaft. All three guide frames are fixedly connected to the measuring base. The three guide frames are arranged in an arc-shaped equidistant distribution. The linkage screw and the threaded sleeve support block are threadedly connected. The reduction angle drive motor and the arc-shaped guide groove plate are fixedly connected. The outer wall of the arc-shaped sliding strip and the inner wall of the arc-shaped guide groove plate are both smooth surfaces.

[0008] Preferably, multiple support blocks are fixedly connected to the inner wall of the arc-shaped guide groove plate and above the arc-shaped sliding strip, and the support blocks are slidably connected to the arc-shaped sliding strip. The multiple support blocks are arranged in an arc-shaped equidistant distribution. The bottom end of the linkage reduction motor is provided with a sleeve slider that is slidably connected to the guide frame plate. A guide rod is horizontally slidably connected inside the sleeve slider and is fixedly connected to the guide frame plate. The linkage reduction motor is fixedly connected to the sleeve slider. An analysis storage disk is fixedly connected to the top of the measuring base, and a bioanalyst is installed on the outside of the measuring base. A sealing hinged cover plate is embedded and hinged at the top of the bioanalyst.

[0009] By adopting the above technical solution, when using the general-purpose bioanalytical instrument for temperature detection, the bioanalytical material is injected into the analytical storage tray. After the sealing hinged cover is closed, the bioanalytical instrument performs temperature-controlled analysis on the bioanalytical material inside the analytical storage tray. Four main temperature sensors can sense the temperature of the bioanalytical material inside the analytical storage tray, and the sensed data is displayed on the display on the surface of the bioanalytical instrument. The starting of the reduction drive motor drives the linkage screw to rotate forward inside the linkage switching frame plate. The threaded sleeve support block drives the reduction angle drive motor to move. The reduction angle drive motor drives the arc guide groove plate to move and expand along the arc sliding bar. At the same time, the support block limits the upper surface of the arc sliding bar. The arc sliding bar drives the linkage reduction motor to move the sleeve slider to the right along the inner wall of the guide frame plate and expands. At the same time, the sleeve slider slides along the outer wall of the guide slide rod. The reduction angle drive motor drives the rotating shaft to move the rotating detection seat. The rotating detection seat drives the energized column to move the main temperature sensor out from inside the analytical storage tray.

[0010] Preferably, the switching assembly includes a rotating detection seat mounted on the top of the rotating shaft, a detection assembly mounted on the top of the arc-shaped guide groove plate, a power-conducting column fixedly connected to one side of the outer wall of the rotating detection seat, and a main temperature sensor fixedly mounted at one end of the power-conducting column with the center of the circle. Multiple spare power-conducting columns are equidistantly distributed in an arc on the outer wall of the rotating detection seat, located on one side of the power-conducting column. A spare temperature sensor is fixedly connected at one end of each spare power-conducting column with the center of the circle. A connecting block is fixedly connected below both the spare power-conducting columns and the power-conducting columns, and a QR code verification strip is welded to the bottom of the connecting block. A sleeve bracket and a detection sensor are sequentially mounted from the outside to the inside on one side of the outer wall of the deceleration angle drive motor. The sleeve bracket is fixedly connected to both the detection sensor and the deceleration angle drive motor. The center point of the main temperature sensor and the center point of the spare power-conducting columns are on the same horizontal plane.

[0011] By adopting the above technical solution, the detection controller starts the reduction rotary motor fixed on the fixed support. The reduction rotary motor drives the linkage shaft to rotate, which in turn drives the gear ring to rotate on the outer wall of the fixed support. At the same time, the gear ring drives the linkage shaft ring to rotate, which in turn drives the rotating sleeve block to rotate the tension rubber ring and the negative electrode induction contact post. The negative electrode induction contact post simultaneously squeezes the positive electrode energizing post. The chamfer of the positive electrode energizing post contacts the chamfer of the negative electrode induction contact post, and the negative electrode induction contact post moves upward from inside the rotating sleeve block. When the bottom end of the negative electrode induction contact post reaches... When the negative electrode contact post is touched, the negative electrode contact post moves downward from inside the rotating socket block. When the positive electrode contact post moves to the right and presses against the positive electrode contact post, the positive electrode contact post drives the linkage ring to move upward. The positive electrode contact post and the positive electrode contact post are aligned, and the negative electrode contact post and the negative electrode contact post are aligned. The positive electrode contact post and the negative electrode contact post are connected to the main temperature sensor through wire harnesses passing through the contact post. This allows for signal sensing of the output current and voltage of the main temperature sensor. The sensed signals are then transmitted to the detection controller by the positive electrode contact post and the negative electrode contact post.

[0012] Preferably, the detection assembly includes a fixed support column mounted on the top of the arc-shaped guide groove plate. A linkage gear ring and a linkage shaft ring are rotatably connected sequentially from top to bottom on the outer wall of the fixed support column. A drive gear ring is meshed and driven on one side of the outer wall of the linkage gear ring. A linkage shaft is inserted and fixedly connected to the inner wall of the drive gear ring, concentrically. A reduction gear rotary motor is installed on one side of the outer wall of the fixed support column near its top, and the output end of the reduction gear rotary motor is coaxially driven and connected to the top of the linkage shaft. A rotating sleeve block is fixedly connected to one side of the outer wall of the linkage shaft ring. Positive induction contacts are slidably connected sequentially from left to right inside the rotating sleeve block. The rotating detection base has a positive electrode induction contact post and a negative electrode induction contact post. Tension rubber rings are provided on the outer walls of both the positive and negative electrode induction contact posts, located above the rotating sleeve block. A linkage ring, fixedly connected to the positive electrode induction contact post, is installed at the top of each tension rubber ring. The tension rubber rings are fixedly connected to both the linkage ring and the rotating sleeve block. Multiple positive electrode energizing posts are fixedly connected to the top of the rotating detection base near its edge. These posts are arranged in a circular, equidistant arrangement. A negative electrode energizing post, fixedly connected to the rotating detection base, is located on one side of each positive electrode energizing post. A detection controller is fixedly connected to the top of the fixed support post.

[0013] By adopting the above technical solution, the linkage reduction motor is started to drive the rotating shaft to rotate, the rotating shaft drives the rotating detection seat to rotate 90 degrees, and the rotating detection seat can also drive the spare power column to rotate the spare temperature sensor. The spare power column drives the connecting block to rotate the QR code verification strip. When the QR code verification strip rotates to the upper surface of the detection sensor, it supports the detection sensor through the sleeve bracket. At the same time, the detection sensor senses the QR code identification data of the QR code verification strip. After sensing, the detection controller shuts off the drive of the reduction angle drive motor or the drive of the other three linkage reduction motors.

[0014] A measurement method comprising the following steps:

[0015] Step 1: When using a general-purpose bioanalytical instrument for temperature detection, inject the bioanalytical material into the analytical storage tray, cover it with a sealed hinged cover, and the bioanalytical instrument will perform temperature-controlled analysis on the bioanalytical material inside the analytical storage tray. Four main temperature sensors can sense the temperature of the bioanalytical material inside the analytical storage tray, and the sensed data is displayed on the display on the surface of the bioanalytical instrument.

[0016] Step 2: When sensor malfunction is detected, the detection controller starts the reduction geared rotary motor fixed on the fixed support. The reduction geared rotary motor drives the linkage shaft to rotate, and simultaneously the linkage shaft drives the drive gear ring to rotate. The drive gear ring drives the linkage gear ring to rotate on the outer wall of the fixed support, and simultaneously the linkage gear ring drives the linkage shaft ring to rotate. The linkage shaft ring drives the rotating sleeve block to rotate the stretching rubber ring and the negative electrode sensing contact post. The negative electrode sensing contact post simultaneously presses against the positive electrode energized post. The chamfer of the positive electrode energized post contacts the chamfer of the negative electrode sensing contact post. The negative electrode sensing contact post will move upward from inside the rotating sleeve block. When the bottom end of the negative electrode sensing contact post contacts the negative electrode energized post, the negative electrode sensing contact post will move downward from inside the rotating sleeve block. Meanwhile, when the positive electrode sensing contact post moves to the right and presses against the positive electrode energized post, the positive electrode sensing... The contact post drives the linkage ring to move upward, and the linkage ring drives the stretching rubber ring to stretch and expand on the upper surface of the rotating sleeve block. This allows the positive induction contact post to be aligned with the positive energized post, and the negative induction contact post to be aligned with the negative energized post. The positive and negative energized posts are connected to the main temperature sensor through wire harnesses passing through the energized posts. This allows the output current and voltage of the main temperature sensor to be sensed. After sensing, the positive and negative induction contact posts transmit the signal to the detection controller. The detection controller senses the output current and voltage of the main temperature sensor. When the current and voltage are within the range set by the detection controller, there is no need to replace the main temperature sensor. When the data sensed by the main temperature sensor exceeds the range set by the detection controller, the reduction drive motor is started.

[0017] Step 3: During the linkage expansion, the reduction drive motor is started, which drives the linkage screw to rotate forward inside the linkage switching frame plate. The linkage screw drives the threaded sleeve support block to move along the inside of the linkage switching frame plate under the action of the thread. At the same time, the threaded sleeve support block drives the reduction angle drive motor to move. The reduction angle drive motor drives the arc-shaped guide groove plate to move and expand along the inside of the arc-shaped sliding bar. Meanwhile, the support block limits the upper surface of the arc-shaped sliding bar. The arc-shaped sliding bar drives the linkage reduction motor to make the sleeve slider move to the right along the inner wall of the guide frame plate and expand. At the same time, the sleeve slider slides along the outer wall of the guide slide rod. Both the linkage reduction motor and the reduction angle drive motor can achieve outward expansion. The reduction angle drive motor drives the rotating shaft to move the rotating detection seat. The rotating detection seat drives the energized column to move the main temperature sensor out from inside the analysis storage disk.

[0018] Step 4: During switching, based on the number of damaged main temperature sensors, the linkage reduction motor is automatically started to drive the rotating shaft to rotate. The rotating shaft drives the rotating detection seat to rotate 90 degrees. At the same time, the rotating detection seat drives the power column to rotate the main temperature sensor. The rotating detection seat can also drive the spare power column to rotate the spare temperature sensor. The spare power column drives the connecting block to rotate the QR code verification bar. When the QR code verification bar rotates to the upper surface of the detection sensor, it supports the detection sensor through the sleeve bracket. At the same time, the detection sensor senses the QR code identification data of the QR code verification bar. When the sensor senses the data, the detection controller shuts off the drive of the reduction angle drive motor or the drive of the other three linkage reduction motors, and the multiple main temperature sensors are replaced and reset.

[0019] Step 5: During reset, the detection controller starts the reduction drive motor, which drives the linkage screw to reverse inside the linkage switching frame. The linkage screw drives the threaded sleeve support block to move along the inside of the linkage switching frame under the action of the thread. At the same time, the threaded sleeve support block drives the reduction angle drive motor to move. The reduction angle drive motor drives the arc-shaped guide groove plate to retract and move along the inside of the arc-shaped sliding bar. The arc-shaped sliding bar drives the linkage reduction motor to move the sleeve slider to the left along the inner wall of the guide frame. At the same time, the sleeve slider slides along the outer wall of the guide slide rod. The distance between the linkage reduction motor and the reduction angle drive motor shortens and approaches. The reduction angle drive motor drives the rotating shaft to move the rotating detection seat. The rotating detection seat drives the spare power column to insert the spare temperature sensor into the analysis storage disk. This allows for precise linkage replacement of multiple damaged main temperature sensors. After rapid replacement, the spare temperature sensor continues to sense the temperature of the analytical materials inside the general bioanalytical instrument. This effectively improves the accuracy of temperature measurement, eliminates the need for waiting and allows for direct switching, avoiding large errors in analytical data caused by abnormal temperatures.

[0020] The technical effects and advantages of this invention are as follows:

[0021] 1. This invention employs a linkage disengagement mechanism. A reduction drive motor drives a linkage screw to rotate forward inside the linkage switching frame plate. The linkage screw drives a threaded sleeve support block to move along the inside of the linkage switching frame plate under the action of the thread. An arc-shaped sliding bar drives a linkage reduction motor to move the sleeve slider to the right along the inner wall of the guide frame plate and expand it. At the same time, the sleeve slider slides along the outer wall of the guide slide rod. The rotating detection seat drives the energizing column to move the main temperature sensor out from inside the analysis storage disk. After automatically replacing the damaged main temperature sensor, the reduction drive motor is restarted to drive the linkage screw to rotate in reverse inside the linkage switching frame plate. The rotating detection seat drives the spare energizing column to insert the spare temperature sensor into the analysis storage disk. This can automatically switch the damaged main temperature sensor. Once damaged, there is no need to wait for professional personnel to repair them one by one. A new spare temperature sensor can be quickly switched to continue measuring the temperature of biological materials that have not been analyzed. The data obtained from the analysis will not be affected by external temperature contamination, thus avoiding affecting the accuracy of data detection and effectively improving the accuracy of data detection.

[0022] 2. This invention employs a switching component to start a linkage reduction motor that drives a rotating shaft to rotate. The rotating shaft then rotates the rotating detection seat 90 degrees. Simultaneously, the rotating detection seat drives an energized column to rotate the main temperature sensor, and a backup energized column to rotate the backup temperature sensor. The backup energized column drives a connecting block to rotate the QR code verification strip. When the QR code verification strip rotates to the upper surface of the detection sensor, the detection controller shuts off the reduction angle drive motor or the other three linkage reduction motors. This allows for precise positioning of the backup temperature sensor's switching position, ensuring more accurate entry of the backup temperature sensor into the analysis storage disk. This guarantees consistent detection positions of the backup temperature sensor within the analysis storage disk, avoiding misalignment and improving temperature detection accuracy.

[0023] 3. This invention uses a detection component to drive a reduction rotary motor to rotate a linkage shaft, which in turn drives a drive gear ring to rotate. The drive gear ring then drives the linkage gear ring to rotate on the outer wall of a fixed support. The linkage shaft ring drives a rotating sleeve block to rotate a stretching rubber ring and a negative electrode sensing contact post. The negative electrode sensing contact post simultaneously presses against the positive electrode energized post. When the bottom of the negative electrode sensing contact post contacts the negative electrode energized post, the negative electrode sensing contact post moves downward from inside the rotating sleeve block. The positive electrode sensing contact post aligns with the positive electrode energized post, and the negative electrode sensing contact post aligns with the negative electrode energized post. This allows for automatic detection of the temperature sensor, ensuring that each temperature sensor is automatically replaced if damaged during use, avoiding large data errors caused by temperature measurement, and improving the accuracy of temperature detection.

[0024] Through the interaction of the above-mentioned multiple functions, the system first automatically detects the temperature sensor, then achieves precise positioning by switching the position of the backup temperature sensor, thus ensuring more accurate entry of the backup temperature sensor into the analysis storage disk. Finally, it automatically switches to a new backup temperature sensor when the main temperature sensor is damaged, eliminating the need to wait for professional personnel to repair each sensor individually. This allows for rapid switching to a new backup temperature sensor to continue measuring the temperature of unanalyzed biological materials, ensuring that the analyzed data is not affected by external temperature contamination. In summary, the system can quickly and simultaneously switch between multiple damaged temperature sensors, ensuring that each temperature sensor remains in normal sensing mode, making temperature measurements more accurate for general-purpose bioanalytical instruments. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of the internal structure of a temperature measuring device for a general-purpose bioanalytical instrument according to the present invention.

[0026] Figure 2 This is a schematic diagram of the main structure of a temperature measuring device for a general-purpose biological analysis instrument according to the present invention.

[0027] Figure 3 This is a schematic diagram of a partial section of the measuring base in a temperature measuring device for a general-purpose biological analysis instrument according to the present invention.

[0028] Figure 4 For the present invention Figure 3 Enlarged structural diagram at point A in the middle.

[0029] Figure 5 This is a bottom view of the connection between the deceleration angle drive motor and the rotating shaft in a temperature measurement device for a general-purpose biological analysis instrument according to the present invention.

[0030] Figure 6 This is a schematic diagram of a partial cut-off structure of the rotating detection seat in a temperature measurement device for a general-purpose biological analysis instrument according to the present invention.

[0031] Figure 7 This is a top view of the connection between the rotating detection seat and the spare power column in a temperature measurement device for a general-purpose biological analysis instrument according to the present invention.

[0032] Figure 8 This is a schematic diagram of a partial cut-off structure of the rotating detection seat in a temperature measurement device for a general-purpose biological analysis instrument according to the present invention.

[0033] The attached figures are labeled as follows: 1. Measuring base; 2. Linkage switching frame plate; 3. Guide frame plate; 4. Linkage screw; 5. Threaded sleeve support block; 6. Gear reduction drive motor; 7. Gear reduction angle drive motor; 8. Arc-shaped guide groove plate; 9. Arc-shaped sliding bar; 10. Support block; 11. Linkage geared motor; 12. Sleeve slider; 13. Guide slide rod; 14. Analysis storage tray; 15. Bioanalyzer; 16. Sealed hinged cover plate; 17. Rotating shaft; 18. Rotating detection seat; 19. Power supply column; 20. Main temperature sensor; 1. Connecting block; 22. QR code verification strip; 23. Detection sensor; 24. Sleeve bracket; 25. Spare power post; 26. Spare temperature sensor; 27. Fixed support; 28. Linkage gear ring; 29. ​​Drive gear ring; 30. Linkage shaft; 31. Gear reducer rotary motor; 32. Linkage shaft ring; 33. Rotary sleeve block; 34. Positive induction contact post; 35. Negative induction contact post; 36. Linkage ring; 37. Tension rubber ring; 38. Positive power post; 39. Negative power post; 40. Detection controller. Detailed Implementation

[0034] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0035] As attached Figure 1-8 The diagram illustrates a temperature measurement device for a general-purpose bioanalytical instrument. This device includes a linkage disengagement mechanism, a switching component, and a detection component. The arrangement of these mechanisms and components enables rapid linkage switching when multiple temperature sensors are damaged, ensuring that each temperature sensor remains in normal sensing mode. This results in more accurate temperature measurements for the general-purpose bioanalytical instrument. The specific structural configuration of each mechanism and component is as follows:

[0036] In some embodiments, as shown in the appendix Figure 1-4As shown, the linkage switching mechanism includes a linkage screw 4 connected inside the linkage switching frame plate 2, and the outer wall of the linkage screw 4 is provided with a threaded sleeve support block 5 that is slidably connected to the linkage switching frame plate 2. One end of the linkage screw 4 extends to the outside of the linkage switching frame plate 2 and is coaxially driven by a reduction drive motor 6. The top end of the threaded sleeve support block 5 is fixedly connected to a reduction angle drive motor 7. An arc-shaped guide groove plate 8 with a cross-sectional shape of arc is welded on one side of the outer wall of the reduction angle drive motor 7, and an arc-shaped sliding strip 9 is slidably connected inside the arc-shaped guide groove plate 8. A linkage reduction motor 11 is fixedly connected to one end of the arc-shaped sliding strip 9. The output ends of the reduction angle drive motor 7 and the linkage reduction motor 11 are both connected to a rotating shaft 17, and a switching component is installed at the top end of the rotating shaft 17.

[0037] In some embodiments, as shown in the appendix Figure 1-4 As shown, multiple support blocks 10 are fixedly connected to the inner wall of the arc-shaped guide groove plate 8 and above the arc-shaped sliding bar 9. The support blocks 10 are slidably connected to the arc-shaped sliding bar 9. The multiple support blocks 10 are arranged in an arc with equal spacing so that the support blocks 10 can limit the upper surface of the arc-shaped sliding bar 9 and ensure that the arc-shaped sliding bar 9 is stably stretched or contracted inside the arc-shaped guide groove plate 8. The bottom end of the linkage reduction motor 11 is provided with a sleeve slider 12 that is slidably connected to the guide frame plate 3. A guide slide rod 13 is horizontally slidably connected inside the sleeve slider 12 and is fixedly connected to the guide frame plate 3. The linkage reduction motor 11 is fixedly connected to the sleeve slider 12 so that the arc-shaped sliding bar 9 can drive the linkage reduction motor 11 to move the sleeve slider. 12 moves to the right along the inner wall of the guide frame plate 3 and expands, while the sleeve slider 12 slides along the outer wall of the guide slide rod 13. The linkage reduction motor 11 can stably play a guiding sliding role. The top of the measuring base 1 is fixedly connected to the analysis storage plate 14, and the bioanalyzer 15 is installed on the outside of the measuring base 1. A sealing hinged cover plate 16 is embedded in the top of the bioanalyzer 15 to facilitate the injection of bioanalytical materials into the analysis storage plate 14. After the sealing hinged cover plate 16 is closed, the bioanalyzer 15 realizes temperature-controlled analysis of the bioanalytical materials inside the analysis storage plate 14. The temperature of the bioanalytical materials inside the analysis storage plate 14 can be sensed by four main temperature sensors 20, realizing multi-point temperature sensing and effectively improving measurement uniformity.

[0038] In some embodiments, as shown in the appendix Figure 2-7As shown, the switching assembly includes a rotating detection seat 18 mounted on the top of the rotating shaft 17, a detection component mounted on the top of the arc-shaped guide plate 8, a power-conducting column 19 fixedly connected to one side of the outer wall of the rotating detection seat 18, and a main temperature sensor 20 fixedly mounted at one end of the power-conducting column 19 with the center of the circle. Multiple spare power-conducting columns 25 are distributed in an arc at equal intervals on the outer wall of the rotating detection seat 18 and on one side of the power-conducting column 19. A spare temperature sensor 26 is fixedly connected at one end of each spare power-conducting column 25 with the center of the circle. A connecting block 21 is fixedly connected below both the spare power-conducting columns 25 and the power-conducting column 19, and a QR code verification strip 22 is welded to the bottom of the connecting block 21. A sleeve bracket 24 and a detection sensor 23 are installed sequentially from the outside to the inside on one side of the outer wall of the deceleration angle drive motor 7. The sleeve bracket 24 is fixedly connected to the detection sensor 23 and the deceleration angle drive motor 7 respectively. The center point of the main temperature sensor 20 and the center point of the spare power-conducting column 25 are on the same horizontal plane.

[0039] In some embodiments, as shown in the appendix Figure 7-8 As shown, the detection assembly includes a fixed support column 27 mounted on the top of the arc-shaped guide groove plate 8. A linkage gear ring 28 and a linkage shaft ring 32 are rotatably connected sequentially from top to bottom on the outer wall of the fixed support column 27. A drive gear ring 29 is meshed and driven on one side of the outer wall of the linkage gear ring 28. A linkage shaft 30 is inserted and fixedly connected to the inner wall of the drive gear ring 29. A reduction rotary motor 31 is installed on one side of the outer wall of the fixed support column 27 near its top. The output end of the reduction rotary motor 31 is coaxially driven and connected to the top of the linkage shaft 30. A rotating sleeve block 33 is fixedly connected to one side of the outer wall of the linkage shaft ring 32. Inside the rotating sleeve block 33, a positive electrode induction contact post 34 and a negative electrode contact post 34 are slidably connected sequentially from left to right. Tension rubber rings 37 are provided on the outer walls of the sensing contact post 35, the positive sensing contact post 34, and the negative sensing contact post 35, and are located above the rotating sleeve block 33. A linkage ring 36, which is fixedly connected to the positive sensing contact post 34, is installed at the top of the tension rubber ring 37. The tension rubber ring 37 is fixedly connected to the linkage ring 36 and the rotating sleeve block 33 respectively. Multiple positive energized posts 38 are fixedly connected to the top of the rotating detection seat 18 near its edge. The multiple positive energized posts 38 are arranged in a circular ring at equal intervals. A negative energized post 39, which is fixedly connected to the rotating detection seat 18, is provided on one side of each positive energized post 38. A detection controller 40 is fixedly connected to the top of the fixed support post 27.

[0040] The working principle of the temperature measurement device for general-purpose bioanalytical instruments of this invention is as follows:

[0041] When using a general-purpose bioanalytical instrument for temperature detection, the bioanalytical material is injected into the analysis storage tray 14, and the sealing hinged cover plate 16 is closed. The bioanalytical instrument 15 performs temperature-controlled analysis on the bioanalytical material inside the analysis storage tray 14. The temperature of the bioanalytical material inside the analysis storage tray 14 can be sensed by four main temperature sensors 20 to obtain accurate temperature data.

[0042] When a sensor malfunctions, the reduction rotary motor 31 drives the linkage shaft 30 to rotate, which in turn drives the drive gear ring 29 to rotate. The drive gear ring 29 then drives the linkage gear ring 28 to rotate on the outer wall of the fixed support 27. The linkage shaft ring 32 drives the rotating sleeve block 33 to rotate the stretching rubber ring 37 and the negative electrode sensing contact post 35. The negative electrode sensing contact post 35 simultaneously presses against the positive electrode energized post 38. The chamfer of the positive electrode energized post 38 contacts the chamfer of the negative electrode sensing contact post 35. The negative electrode sensing contact post 35 moves upward from inside the rotating sleeve block 33. When the bottom of the negative electrode sensing contact post 35 contacts the negative electrode energized post 39, the negative electrode sensing contact post 35 moves downward from inside the rotating sleeve block 33. Meanwhile, when the positive electrode sensing contact post 34 moves to the right and presses against the positive electrode energized post 38, the positive electrode sensing contact post... 34 drives the linkage ring 36 to move upward, and the linkage ring 36 drives the stretching rubber ring 37 to stretch and expand on the upper surface of the rotating sleeve block 33, so that the positive electrode sensing contact post 34 and the positive electrode energizing post 38 are energized and aligned, and the negative electrode sensing contact post 35 and the negative electrode energizing post 39 are energized and aligned. The positive electrode energizing post 38 and the negative electrode energizing post 39 are connected to the main temperature sensor 20 through the wire harness passing through the energizing post 19, so that the output current and voltage of the main temperature sensor 20 can be sensed. The output current and voltage of the main temperature sensor 20 are sensed by the detection controller 40. When the current and voltage are within the range set by the detection controller 40, there is no need to replace the main temperature sensor 20. When the data sensed by the main temperature sensor 20 exceeds the range set by the detection controller 40, the reduction drive motor 6 can be started.

[0043] During the linkage expansion, the reduction drive motor 6 drives the linkage screw 4 to rotate forward inside the linkage switching frame plate 2. The linkage screw 4 drives the threaded sleeve support block 5 to move along the inside of the linkage switching frame plate 2 under the action of the thread. The reduction angle drive motor 7 drives the arc guide groove plate 8 to move and expand along the inside of the arc sliding bar 9. The arc sliding bar 9 drives the linkage reduction motor 11 to make the sleeve slider 12 move to the right along the inner wall of the guide frame plate 3 to expand. At the same time, the sleeve slider 12 slides along the outer wall of the guide slide bar 13. Both the linkage reduction motor 11 and the reduction angle drive motor 7 can achieve outward expansion. The reduction angle drive motor 7 drives the rotating shaft 17 to move the rotating detection seat 18. The rotating detection seat 18 drives the energized column 19 to move the main temperature sensor 20 out from the analysis storage disk 14.

[0044] During switching, the linkage reduction motor 11 is started to drive the rotating shaft 17 to rotate, the rotating shaft 17 drives the rotating detection seat 18 to rotate 90 degrees, and at the same time the rotating detection seat 18 drives the power column 19 to rotate the main temperature sensor 20, the standby power column 25 to rotate the standby temperature sensor 26, the standby power column 25 drives the connecting block 21 to rotate the QR code verification strip 22, when the QR code verification strip 22 rotates to the upper surface of the detection sensor 23, the detection sensor 23 senses the QR code identification data of the QR code verification strip 22, and after sensing, the detection controller 40 shuts down the reduction angle drive motor 7 or the other three linkage reduction motors 11;

[0045] During reset, the detection controller 40 starts the reduction drive motor 6, which drives the linkage screw 4 to reverse inside the linkage switching frame plate 2. The linkage screw 4 drives the threaded sleeve support block 5 to move along the inside of the linkage switching frame plate 2 under the action of the thread. The reduction angle drive motor 7 drives the arc guide groove plate 8 to retract and move along the inside of the arc sliding bar 9. The arc sliding bar 9 drives the linkage reduction motor 11 to make the sleeve slider 12 move to the left along the inner wall of the guide frame plate 3. The distance between the linkage reduction motor 11 and the reduction angle drive motor 7 shortens and approaches. The reduction angle drive motor 7 drives the rotating shaft 17 to move the rotating detection seat 18. The rotating detection seat 18 drives the spare power column 25 to insert the spare temperature sensor 26 into the analysis storage disk 14, which can accurately replace multiple damaged main temperature sensors 20.

[0046] All contents not described in detail in the specification are existing technologies known to those skilled in the art, and the model parameters of each electrical appliance are not specifically limited and can be determined using conventional equipment. Electrical control components not mentioned in this technical solution are not shown in the figures because they are existing technologies, and will not be described here.

[0047] The above are merely preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A temperature measuring device for a general-purpose bioanalytical instrument, comprising a measuring base (1), wherein a linkage switching frame plate (2) is fixedly connected to one side of the outer wall of the measuring base (1), and three guide frames (3) are provided on the outer wall of the measuring base (1) and at one side of the linkage switching frame plate (2), characterized in that: The linkage switching frame plate (2) is internally connected to a linkage disengagement mechanism; The linkage switching mechanism includes a linkage screw (4) connected inside the linkage switching frame plate (2), and the outer wall of the linkage screw (4) is provided with a threaded sleeve support block (5) that is slidably connected to the linkage switching frame plate (2). One end of the linkage screw (4) extends to the outside of the linkage switching frame plate (2) and is coaxially connected to a reduction drive motor (6). The top end of the threaded sleeve support block (5) is fixedly connected to a reduction angle drive motor (7). An arc-shaped guide groove plate (8) with a circular arc cross-section is welded on one side of the outer wall of the reduction angle drive motor (7), and an arc-shaped sliding strip (9) is slidably connected inside the arc-shaped guide groove plate (8). A linkage reduction motor (11) is fixedly connected to one end of the arc-shaped sliding strip (9). The output ends of the reduction angle drive motor (7) and the linkage reduction motor (11) are both connected to a rotating shaft (17), and a switching component is installed at the top end of the rotating shaft (17).

2. The temperature measuring device for a general-purpose biological analysis instrument according to claim 1, characterized in that: All three guide frames (3) are fixedly connected to the measuring base (1). The three guide frames (3) are arranged in an arc with equal spacing, and the linkage screw (4) is threadedly connected to the threaded sleeve support block (5).

3. The temperature measuring device for a general-purpose bioanalytical instrument according to claim 1, characterized in that: The deceleration angle drive motor (7) is fixedly connected to the arc-shaped guide groove plate (8), and the outer wall of the arc-shaped sliding strip (9) and the inner wall of the arc-shaped guide groove plate (8) are both made into smooth surfaces.

4. The temperature measuring device for a general-purpose biological analysis instrument according to claim 1, characterized in that: Multiple support blocks (10) are fixedly connected to the inner wall of the arc-shaped guide groove plate (8) and above the arc-shaped sliding bar (9), and the support blocks (10) are slidably connected to the arc-shaped sliding bar (9). The multiple support blocks (10) are arranged in an arc-shaped equidistant distribution.

5. The temperature measuring device for a general-purpose bioanalytical instrument according to claim 1, characterized in that: The bottom end of the linkage reduction motor (11) is provided with a sleeve slider (12) that is slidably connected to the guide frame plate (3). A guide slide rod (13) is horizontally slidably connected inside the sleeve slider (12), and the guide slide rod (13) is fixedly connected to the guide frame plate (3). The linkage reduction motor (11) is fixedly connected to the sleeve slider (12).

6. The temperature measuring device for a general-purpose bioanalytical instrument according to claim 1, characterized in that: The top of the measuring base (1) is fixedly connected to an analysis storage disk (14), and a bioanalyzer (15) is installed on the outside of the measuring base (1). A sealing hinged cover plate (16) is embedded in the top of the bioanalyzer (15).

7. The temperature measuring device for a general-purpose bioanalytical instrument according to claim 1, characterized in that: The switching assembly includes a rotating detection seat (18) installed at the top of the rotating shaft (17), a detection assembly installed at the top of the arc-shaped guide groove plate (8), a power-conducting column (19) fixedly connected to one side of the outer wall of the rotating detection seat (18), and a main temperature sensor (20) fixedly installed at one end of the power-conducting column (19) with the center. Multiple spare power-conducting columns (25) are distributed in an arc at equal intervals on the outer wall of the rotating detection seat (18) and at one side of the power-conducting column (19). A spare temperature sensor (26) is fixedly connected at one end of each spare power-conducting column (25) with the center. A connecting block (21) is fixedly connected below the spare power-conducting column (25) and the power-conducting column (19), and a QR code verification strip (22) is welded to the bottom of the connecting block (21). A sleeve bracket (24) and a detection sensor (23) are installed sequentially from the outside to the inside on one side of the outer wall of the deceleration angle drive motor (7).

8. The temperature measuring device for a general-purpose bioanalytical instrument according to claim 7, characterized in that: The sleeve bracket (24) is fixedly connected to the detection sensor (23) and the deceleration angle drive motor (7) respectively. The center point of the main temperature sensor (20) and the center point of the spare power column (25) are on the same horizontal plane.

9. A temperature measuring device for a general-purpose bioanalytical instrument according to claim 7, characterized in that: The detection assembly includes a fixed support column (27) mounted on the top of the arc-shaped guide groove plate (8). A linkage gear ring (28) and a linkage rotating shaft ring (32) are rotatably connected from top to bottom on the outer wall of the fixed support column (27). A drive gear ring (29) is meshed and driven on one side of the outer wall of the linkage gear ring (28). A linkage rotating shaft (30) is inserted and fixedly connected to the inner wall of the drive gear ring (29) in a concentric circle. A reduction rotary motor (31) is installed on one side of the outer wall of the fixed support column (27) near its top. The output end of the reduction rotary motor (31) is coaxially driven and connected to the top of the linkage rotating shaft (30). A rotating sleeve block (33) is fixedly connected to one side of the outer wall of the linkage rotating shaft ring (32). A positive induction contact post (34) and a negative induction contact post (35) are slidably connected from left to right inside the rotating sleeve block (33). The outer walls of the contact post (35), the positive induction contact post (34) and the negative induction contact post (35) are provided with tension rubber rings (37) located above the rotating sleeve block (33). A linkage ring (36) fixedly connected to the positive induction contact post (34) is installed at the top of the tension rubber ring (37). The tension rubber ring (37) is fixedly connected to the linkage ring (36) and the rotating sleeve block (33) respectively. Multiple positive energizing posts (38) are fixedly connected at the top of the rotating detection seat (18) near its edge. The multiple positive energizing posts (38) are arranged in a circular ring at equal intervals. A negative energizing post (39) fixedly connected to the rotating detection seat (18) is provided on one side of each positive energizing post (38). A detection controller (40) is fixedly connected at the top of the fixed support post (27).

10. A measurement method using the temperature measuring device for a general-purpose bioanalytical instrument as described in any one of claims 1-9, characterized in that: The method includes the following steps: Step 1: When using a general bioanalytical instrument for temperature detection, inject the bioanalytical material into the analysis storage tray (14), and cover it with a sealing hinged cover plate (16). The bioanalytical instrument (15) performs temperature-controlled analysis on the bioanalytical material inside the analysis storage tray (14). The temperature of the bioanalytical material inside the analysis storage tray (14) can be sensed by four main temperature sensors (20), and the sensed data is displayed on the display on the surface of the bioanalytical instrument (15). Step 2: When the sensor detects an anomaly, the detection controller (40) starts the reduction rotary motor (31) fixed on the fixed support column (27). The reduction rotary motor (31) drives the linkage shaft (30) to rotate, and at the same time, the linkage shaft (30) drives the drive gear ring (29) to rotate. The drive gear ring (29) drives the linkage gear ring (28) to rotate on the outer wall of the fixed support column (27). At the same time, the linkage gear ring (28) drives the linkage shaft ring (32) to rotate, and the linkage shaft ring (32) drives the rotating sleeve block (33) to stretch the rubber ring (3). 7) As the negative induction contact post (35) rotates, it simultaneously presses against the positive energizing post (38). The chamfer of the positive energizing post (38) contacts the chamfer of the negative induction contact post (35), causing the negative induction contact post (35) to move upward from inside the rotating sleeve block (33). When the bottom end of the negative induction contact post (35) contacts the negative energizing post (39), the negative induction contact post (35) moves downward from inside the rotating sleeve block (33), while the positive induction contact post (34) moves to the right to press against the positive energizing post. When (38) is reached, the positive induction contact post (34) drives the linkage ring (36) to move upward. The linkage ring (36) drives the stretching rubber ring (37) to stretch and expand on the upper surface of the rotating sleeve block (33), so that the positive induction contact post (34) and the positive energizing post (38) are energized and aligned, and the negative induction contact post (35) and the negative energizing post (39) are energized and aligned. The positive energizing post (38) and the negative energizing post (39) are connected to the main temperature sensor (20) through the energizing post (19) via a wire harness, so that the main temperature sensor (20) can be energized. The output current and voltage of the main temperature sensor (20) are sensed by the positive induction contact post (34) and the negative induction contact post (35). After sensing, the signal is transmitted to the detection controller (40). The detection controller (40) senses the output current and voltage of the main temperature sensor (20). When the current and voltage are within the range set by the detection controller (40), the main temperature sensor (20) does not need to be replaced. When the data sensed by the main temperature sensor (20) exceeds the range set by the detection controller (40), the geared drive motor (6) can be started. Step 3: During the linkage expansion, the reduction drive motor (6) is started, driving the linkage screw (4) to rotate forward inside the linkage switching frame plate (2). The linkage screw (4) drives the threaded sleeve support block (5) to move along the linkage switching frame plate (2) under the action of the thread. At the same time, the threaded sleeve support block (5) drives the reduction angle drive motor (7) to move. The reduction angle drive motor (7) drives the arc-shaped guide groove plate (8) to move and expand along the arc-shaped sliding bar (9). At the same time, the support block (10) limits the upper surface of the arc-shaped sliding bar (9), while the arc-shaped sliding bar (9) moves along the arc-shaped sliding bar (9). The sliding bar (9) drives the linkage reduction motor (11) to make the sleeve slider (12) move to the right along the inner wall of the guide frame plate (3) and expand. At the same time, the sleeve slider (12) slides along the outer wall of the guide slide rod (13). Both the linkage reduction motor (11) and the reduction angle drive motor (7) can expand outward. The reduction angle drive motor (7) drives the rotating shaft (17) to move the rotating detection seat (18). The rotating detection seat (18) drives the energized column (19) to move the main temperature sensor (20) out from the inside of the analysis storage disk (14). Step 4: During the switching process, based on the number of damaged main temperature sensors (20), the linkage reduction motor (11) is automatically started to drive the rotating shaft (17) to rotate. The rotating shaft (17) drives the rotating detection seat (18) to rotate 90 degrees. At the same time, the rotating detection seat (18) drives the power column (19) to make the main temperature sensor (20) rotate. The rotating detection seat (18) can also drive the spare power column (25) to make the spare temperature sensor (26) rotate. The spare power column (25) drives the connecting block (21) to make the QR code verification strip (22) rotate. When the QR code verification strip (22) rotates to the upper surface of the detection sensor (23), it supports the detection sensor (23) through the sleeve bracket (24). At the same time, the detection sensor (23) senses the QR code identification data of the QR code verification strip (22). When the data is sensed, the detection controller (40) turns off the drive of the deceleration angle drive motor (7) or the drive of the other three linkage reduction motors (11) to replace multiple main temperature sensors (20) and reset. Step 5: During reset, the detection controller (40) starts the reduction drive motor (6), which drives the linkage screw (4) to reverse inside the linkage switching frame plate (2). The linkage screw (4) drives the threaded sleeve support block (5) to move inside the linkage switching frame plate (2) under the action of the thread. At the same time, the threaded sleeve support block (5) drives the reduction angle drive motor (7) to move. The reduction angle drive motor (7) drives the arc guide groove plate (8) to retract and move inside the arc sliding bar (9). The arc sliding bar (9) drives the linkage reduction motor (11) to make the sleeve slider (12) move to the left along the inner wall of the guide frame plate (3). Meanwhile, the sleeve slider (12) moves along the guide slide bar (13). The outer wall slides, the distance between the linkage reduction motor (11) and the reduction angle drive motor (7) shortens and approaches, the reduction angle drive motor (7) drives the rotating shaft (17) to move the rotating detection seat (18), the rotating detection seat (18) drives the spare power column (25) to insert the spare temperature sensor (26) into the analysis storage disk (14), which can accurately link and replace multiple damaged main temperature sensors (20). After the quick replacement, the spare temperature sensor (26) continues to sense the temperature of the analytical material inside the general biological analyzer. In this way, the temperature measurement accuracy is effectively improved, and there is no need to wait for direct switching, avoiding the occurrence of temperature abnormalities that cause large errors in the analysis data.

Images