Medicine simmering-cooling-sample injection-imaging integrated device for analyzing traditional Chinese medicine components by micro-fluidic chip

Abstract

The invention provides a medicine simmering-cooling-sample introduction-imaging integrated device for analyzing traditional Chinese medicine components by a micro-fluidic chip, and relates to the technical field of traditional Chinese medicine analysis and micro-fluidic, and the device comprises a medicine simmering module, a cooling module, a sample introduction module and an imaging module. The medicine simmering module is used for simmering a traditional Chinese medicine sample in a high-frequency induction heating mode, magnetic heat eddy current heating is generated through an iron core, heat is transferred to a screw spherical reaction bottle through a small iron bowl, and the cooling module is used for condensing steam containing traditional Chinese medicine ingredients generated in the medicine simmering process through a first peristaltic pump and a condensation pipe, so that traditional Chinese medicine liquid is reduced to a proper degree; condensed traditional Chinese medicine liquid enters a conical flask and is selectively introduced into different micro-fluidic chips for analysis under the control of an electromagnetic valve; the sample injection module realizes accurate sample injection of a plurality of micro-fluidic chips through an adjustable X-axis displacement table and an adjustable Y-axis displacement table; the imaging module is used for fixing mobile terminal imaging equipment through a Z-axis displacement table and observing the flowing and reaction process of traditional Chinese medicine liquid in the micro-fluidic chip in real time.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine analysis and microfluidics technology, and in particular to an integrated device for simmering, cooling, sample introduction, and imaging of traditional Chinese medicine components using microfluidic chips. Background Technology

[0002] With the deepening application of microfluidic chip technology in chemical analysis, biological detection, and research on traditional Chinese medicine components, it has gradually become an important technical means for rapid analysis of traditional Chinese medicine components due to its advantages of small device size, fast reaction speed, and high detection sensitivity. However, the existing equipment used for analyzing traditional Chinese medicine components is relatively large in overall size and lacks a cooling module, which is incompatible with the functions of microfluidic chips. Traditional Chinese medicine simmering usually relies on heating plates, water baths, or open flames, which results in slow heating, difficulty in temperature control, and difficulty in direct connection with subsequent analysis units, making it unsuitable for the rapid processing of small-volume samples required by microfluidic chips. After simmering, the medicinal liquid usually needs to be cooled by natural cooling or external cooling devices, which not only has low cooling efficiency but also increases sample exposure and transfer steps, making it difficult to meet the continuity and timeliness requirements of microfluidic chips. In addition, existing sample introduction methods mostly rely on manual pouring, syringes, or external tubing, which are cumbersome and easily introduce air bubbles or impurities during multiple sample transfers, affecting the stability of the fluid state within the microscale channels and reducing the reliability of the analytical results. In terms of imaging, traditional devices typically require large-volume microscopic imaging systems, which do not match the goal of portability and low-cost application of microfluidic chips.

[0003] Therefore, there is still a lack of a traditional Chinese medicine component extraction device in the existing technology that can match the microfluidic chip in terms of size and functional integration. This device needs to achieve efficient integration of traditional Chinese medicine preparation, rapid cooling and selective sample introduction while maintaining a compact and miniaturized overall structure, and serve the analytical application requirements of microfluidic chips for miniaturization, high efficiency and high sensitivity. Summary of the Invention

[0004] To address the problems of large size, fragmented processing flow, and slow sample injection speed in existing traditional Chinese medicine (TCM) component extraction equipment, an integrated device for TCM component analysis using microfluidic chips is proposed, combining decoction, cooling, sample injection, and imaging. This device integrates decoction, cooling, sample injection, and imaging functions into a single unit, achieving rapid extraction of TCM components within a compact structure. It is suitable for room temperature detection applications using microfluidic chips.

[0005] The specific technical solution of the present invention is as follows:

[0006] An integrated device for simmering, cooling, sample injection, and imaging of traditional Chinese medicine components using a microfluidic chip includes a simmering module, a cooling module, a sample injection module, and an imaging module. Each module is controlled as a whole via a control panel. The control panel features a seven-segment digital temperature display and switches, including a simmering switch, a cooling switch, a solenoid valve switch, and an imaging switch, corresponding to the simmering module, cooling module, sample injection module, and imaging module, respectively. When a switch is turned on, the corresponding module is activated. The cooling switch includes a first peristaltic pump adjustment knob and a second peristaltic pump adjustment knob.

[0007] The herbal simmering module is used to heat and simmer Chinese herbal medicine samples. It includes a support rod, a support structure, a cross clamp, a crab claw clamp, a high-frequency induction circuit board, a cooling fan, high-temperature ceramic terminals, an iron core, a copper core coil, a screw-top spherical reaction flask, and a small iron bowl. When the simmering switch on the control panel is turned on, the module begins operation. The support rod is fixed to the support structure, and the cross clamp and crab claw clamp support and adjust the position of the high-frequency induction circuit board, cooling fan, copper core coil, screw-top spherical reaction flask, and small iron bowl of the simmering module. The high-frequency induction circuit board is... The iron core is fixed to one side of the support rod and connected to the copper core coil, which is wound around the outside of the iron core. When the high-frequency induction circuit board is working, it drives the cooling fan to start. The iron core, as a heat-conducting and induction heating component, generates a magnetothermal eddy current effect and heats up rapidly. One end of the iron core is connected to a high-temperature ceramic terminal, and the other end of the iron core is fixed to the iron bowl. The iron bowl and the iron core are in thermal contact, which conducts the heat generated by the iron core to the internal space of the iron bowl. The screw-top spherical reaction bottle is placed inside the iron bowl. The screw-top spherical reaction bottle is used to hold the Chinese medicine sample and the water for simmering.

[0008] The screw-top spherical reaction flask has a capacity of 50ml and is a three-necked flask. The three necks are A, B, and O. Cavity A is located at the center of the top of the screw-top spherical reaction flask and is the main vertical interface. Cavity B is an opening on the side of the screw-top spherical reaction flask that is angled upwards and forms a certain angle with Cavity A. Cavity O is a third opening on the side of the screw-top spherical reaction flask that is opposite to or at a certain angle to Cavity B, and its height is lower than that of Cavity B. When simmering the medicine, the Chinese medicine and simmering water are added through Cavity A, and the steam containing the Chinese medicine components will enter the cooling module through Cavity O.

[0009] When the high-frequency induction circuit board is working, it drives the copper core coil to generate a high-frequency induced electromagnetic field, which generates a magnetothermal eddy current effect in the iron core, causing the iron core and the iron bowl to heat up rapidly. The heat is evenly conducted through the iron bowl to the screw-top spherical reaction flask, and then transmitted to the seven-segment digital tube temperature display on the control panel for real-time monitoring via the temperature sensor.

[0010] The cooling module is used to condense and cool the steam containing Chinese herbal ingredients generated during the simmering process and to provide Chinese herbal liquid to the sample injection module. Specifically, it includes a first peristaltic pump, a second peristaltic pump, a condenser tube, and a conical flask. The condenser tube is inclinedly fixed to the support structure by a crab claw clamp. The condenser tube has a condensate inlet W1, a condensate outlet W2, an upper port O1, and a lower port O2. The first peristaltic pump is connected to the W1 and W2 ports of the condenser tube and is controlled by the first peristaltic pump adjustment knob on the control panel. It continuously delivers condensate into the condenser tube through the condensate inlet W1. The condensate flows into the conical flask from the lower port O2 of the condenser tube for collection and temporary storage.

[0011] The screw-top spherical reaction flask, condenser, conical flask, first peristaltic pump, and second peristaltic pump are connected by PVC sleeves. The conical flask includes an O3 port, a C port, and a D port. The O3 port is connected to the lower O2 port of the condenser, the C port is connected to the second peristaltic pump, and the D port is connected to the microfluidic chip. The second peristaltic pump controls the pump rate via the second peristaltic pump adjustment knob on the control panel to increase the pressure inside the conical flask. The Chinese medicine solution inside the conical flask is then introduced from the D port through a four-way solenoid valve into the sample introduction channel of the microfluidic chip in the sample introduction module.

[0012] The sample introduction module is used to introduce the traditional Chinese medicine solution into the microfluidic chip for analysis. Specifically, it includes an X-axis displacement stage, a Y-axis displacement stage, a microfluidic chip mounting stage, and the microfluidic chip itself. The X-axis and Y-axis displacement stages are mounted on a support structure, and each stage has a microfluidic chip mounting stage for supporting the microfluidic chip. Several microfluidic chip mounting stages are arranged in a matrix to simultaneously hold multiple microfluidic chips. The X-axis and Y-axis displacement stages are used for fine adjustment of the two-dimensional position of the microfluidic chip in the horizontal direction.

[0013] The herbal liquid processed by the cooling module is selectively introduced into the corresponding microfluidic chip under the control of the solenoid valve switch on the control panel, realizing independent sample introduction and switching between different chips.

[0014] The imaging module is used to display the flow state and reaction process of the traditional Chinese medicine liquid in the microfluidic chip in real time. It includes a fixed frame, a Z-axis displacement stage, a chamfered frame, and a mobile terminal device. The fixed frame is placed on the support structure, the Z-axis displacement stage is located on the fixed frame, and the chamfered frame is set on the Z-axis displacement stage for fixing the mobile terminal device.

[0015] The fixed mobile terminal device is equipped with a microscope lens and a magnifying glass to amplify, collect, and record the flow, diffusion, and reaction processes of the traditional Chinese medicine liquid within the microfluidic chip in real time, enabling intuitive observation of the analysis process.

[0016] The beneficial effects of adopting the above technical solution are as follows:

[0017] This invention provides an integrated device for simmering, cooling, sample introduction, and imaging of traditional Chinese medicine components using microfluidic chips. This invention has the following beneficial effects:

[0018] (1) The present invention integrates the functions of simmering medicine, cooling, sample injection and imaging into the same device. The overall structure is compact and occupies little space. It can match the miniaturization characteristics of microfluidic chips and is conducive to building a small-sized and highly integrated Chinese medicine component analysis system.

[0019] (2) The present invention uses induction heating to achieve rapid simmering of Chinese medicine, and uses a condenser tube and a peristaltic pump 1 to cool the steam containing Chinese medicine components in real time, which shortens the processing and sample preparation time of Chinese medicine, improves the overall speed of sample processing and detection, and is suitable for rapid analysis applications.

[0020] (3) The present invention can directly introduce the traditional Chinese medicine liquid into the microfluidic chip without changing the container during the sample introduction process, which reduces the sample transfer process, reduces the risk of airborne suspended matter or impurities, and helps to maintain the cleanliness of the sample and improve the sensitivity of microfluidic detection.

[0021] (4) The present invention uses a mobile terminal imaging device to observe the Chinese medicine liquid inside the microfluidic chip, and uses a Z-axis displacement stage to achieve clear imaging. While meeting the observation requirements, it reduces the system cost and is suitable for widespread application. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the module structure of an integrated device for simmering, cooling, sample introduction, and imaging of traditional Chinese medicine components for microfluidic chip analysis according to the present invention.

[0023] Figure 2 This is a schematic diagram of the decoction module of an integrated device for decoction-cooling-sample injection-imaging of traditional Chinese medicine components for microfluidic chip analysis according to the present invention.

[0024] Figure 3 This is a schematic diagram of the cooling module of an integrated device for simmering, cooling, sample introduction, and imaging of traditional Chinese medicine components for microfluidic chip analysis according to the present invention.

[0025] Figure 4 This is a schematic diagram of the sample introduction module of an integrated device for simmering, cooling, sample introduction, and imaging of traditional Chinese medicine components for microfluidic chip analysis according to the present invention.

[0026] Figure 5 This is a schematic diagram of the imaging module of an integrated device for simmering, cooling, sample injection, and imaging of traditional Chinese medicine components for microfluidic chip analysis, as described in this invention.

[0027] In the diagram: 1-Support rod, 2-Cross clamp, 3-High frequency induction circuit board, 4-Cooling fan, 5-High temperature ceramic terminal block, 6-Iron core, 7-Copper core coil, 8-Screw-type spherical reaction flask, 9-Iron bowl, 10-Temperature sensor, 11-Crab claw clamp, 12-Condenser tube, 13-Conical flask, 14-Solenoid valve, 15-X-axis displacement stage, 16-Y-axis displacement stage, 17-Microfluidic chip mounting stage, 18-Microfluidic chip, 19-Mounting frame, 20-Z-axis displacement stage, 21-Chamfered frame. Detailed Implementation

[0028] The specific implementation methods of this application will be further described in detail below with reference to the accompanying drawings and embodiments.

[0029] An integrated device for simmering, cooling, sample introduction, and imaging of traditional Chinese medicine components using microfluidic chips, such as... Figure 1 As shown, the system includes a decoction preparation module, a cooling module, a sample injection module, and an imaging module. These modules are spatially coordinated and functionally sequentially connected. A control panel provides overall control of each module. The control panel features a seven-segment digital temperature display and switches, including a decoction preparation switch, a cooling switch, a solenoid valve switch, and an imaging switch, corresponding to the decoction preparation module, cooling module, sample injection module, and imaging module, respectively. When a switch is turned on, it drives the corresponding module to operate. The cooling switch includes a first peristaltic pump adjustment knob and a second peristaltic pump adjustment knob.

[0030] The herb-stewing module is used to heat and stew traditional Chinese medicine samples, such as... Figure 2 As shown, the system includes a support rod 1, a support structure, a cross clamp 2, a crab claw clamp 11-frequency induction circuit board 3, a cooling fan 4, a high-temperature ceramic terminal block 5, an iron core 6, a copper core coil 7, a screw-top spherical reaction flask 8, and an iron bowl 9. When the simmering switch on the control panel is turned on, the simmering module starts operating. The support rod is fixed to the support structure, and the cross clamp and crab claw clamp support and adjust the position of the high-frequency induction circuit board, cooling fan, copper core coil, screw-top spherical reaction flask, and iron bowl of the simmering module. The high-frequency induction circuit board is fixed to one side of the support rod and connected to the copper core coil. A copper core coil is wound around the outside of the iron core. When the high-frequency induction circuit board is working, it drives the cooling fan to start. The iron core, as a heat-conducting and induction heating component, generates a magnetothermal eddy current effect and rapidly heats up under the action of a high-frequency alternating electromagnetic field. One end of the iron core is connected to a high-temperature ceramic terminal to prevent heat loss, and the other end of the iron core is fixed to the iron bowl. The iron bowl and the iron core are in thermal contact, which conducts the heat generated by the iron core to the internal space of the iron bowl. The screw-top spherical reaction bottle is placed inside the iron bowl. The screw-top spherical reaction bottle is used to hold the Chinese medicine sample and the water for simmering, forming a relatively closed simmering environment.

[0031] The screw-top spherical reaction flask has a capacity of 50ml and is a three-necked flask. The three necks are A, B, and O. Cavity A is located at the center of the top of the screw-top spherical reaction flask and is the main vertical interface. Cavity B is an opening on the side of the screw-top spherical reaction flask that is angled upwards and forms a certain angle with Cavity A. Cavity O is a third opening on the side of the screw-top spherical reaction flask that is opposite to or at a certain angle to Cavity B, and its height is lower than that of Cavity B. When simmering the medicine, the Chinese medicine and simmering water are added through Cavity A, and the steam containing the Chinese medicine components will enter the cooling module through Cavity O.

[0032] When the high-frequency induction circuit board is working, it drives the copper core coil to generate a high-frequency induced electromagnetic field, which generates a magnetothermal eddy current effect in the iron core, causing the iron core and the iron bowl to heat up rapidly. The heat is evenly conducted through the iron bowl to the screw-top spherical reaction flask, and is monitored in real time by the seven-segment digital tube temperature display on the temperature sensor 10 control panel, thereby realizing a temperature-controlled simmering solution.

[0033] The cooling module is used to condense and cool the steam containing Chinese herbal ingredients generated during the simmering process, and to provide the sample injection module with a Chinese herbal liquid at a suitable temperature, such as... Figure 3 As shown, the system specifically includes a first peristaltic pump, a second peristaltic pump, a condenser tube 12, and a conical flask 13. The condenser tube is inclinedly fixed to the support structure by a crab claw clamp. The condenser tube has a condensate inlet W1, a condensate outlet W2, an upper port O1, and a lower port O2. The first peristaltic pump is connected to the W1 and W2 ports of the condenser tube and is controlled by the first peristaltic pump adjustment knob on the control panel. It continuously delivers condensate into the condenser tube through the condensate inlet W1 to form a stable cooling environment inside the condenser tube. During the process of simmering Chinese medicine, the steam containing Chinese medicine components generated by the simmering module enters the condenser tube and is condensed into room temperature condensate under the action of the condensate delivered by the first peristaltic pump. The condensate flows into the conical flask from the lower port O2 of the condenser tube for collection and temporary storage.

[0034] The screw-top spherical reaction flask, condenser, conical flask, first peristaltic pump, and second peristaltic pump are connected by PVC tubing. The conical flask includes an O3 port, a C port, and a D port. The O3 port connects to the lower O2 port of the condenser, the C port connects to the second peristaltic pump, and the D port connects to the microfluidic chip. The second peristaltic pump controls the pump rate via a knob on the control panel, increasing the pressure inside the conical flask. The herbal liquid inside the conical flask is then introduced from the D port through a four-way solenoid valve 14 into the microfluidic chip's injection channel in the injection module. By controlling the solenoid valve, the condensed herbal liquid is selectively introduced into the corresponding microfluidic chip, enabling independent injection and switching under multi-chip conditions.

[0035] The sample introduction module is used to introduce the traditional Chinese medicine solution into the microfluidic chip for analysis, such as... Figure 4As shown, the system specifically includes an X-axis displacement stage, a Y-axis displacement stage, a microfluidic chip mounting stage, and a microfluidic chip. The X-axis displacement stage 15 and Y-axis displacement stage 16 are mounted on a support structure. Each X-axis and Y-axis displacement stage has a microfluidic chip mounting stage 17 for supporting the microfluidic chip. Several microfluidic chip mounting stages are arranged in a matrix to simultaneously hold multiple microfluidic chips 18. In this embodiment, four microfluidic chips (2×2) are placed on the microfluidic chip mounting stages to meet the needs of multi-channel analysis. The X-axis and Y-axis displacement stages are used for fine adjustment of the two-dimensional position of the microfluidic chip in the horizontal direction to achieve accurate alignment between the microfluidic chip and the sample introduction path.

[0036] The herbal liquid processed by the cooling module is selectively introduced into the corresponding microfluidic chip under the control of the solenoid valve switch on the control panel, realizing independent sample introduction and switching between different chips.

[0037] The imaging module is used to display the flow state and reaction process of the traditional Chinese medicine solution within the microfluidic chip in real time, such as... Figure 5 As shown, the device includes a mounting bracket 19, a Z-axis displacement stage 20, a chamfering bracket 21, and a mobile terminal device. The mounting bracket is placed on a support structure, and the Z-axis displacement stage is located on the mounting bracket, used to adjust the vertical position of the chamfering bracket. The chamfering bracket is set on the Z-axis displacement stage to fix the mobile terminal device, ensuring a stable relative position between the phone's lens and the microfluidic chip. By adjusting the Z-axis displacement stage, the working distance between the phone's lens and the microfluidic chip can be changed to obtain a clear imaging effect.

[0038] The fixed mobile terminal device is equipped with a microscope lens and a magnifying glass to amplify, collect, and record the flow, diffusion, and reaction processes of the traditional Chinese medicine liquid within the microfluidic chip in real time, enabling intuitive observation of the analysis process.

[0039] The various embodiments in this application are described in a progressive manner. The same or similar parts between the various embodiments can be referred to each other. Each embodiment focuses on describing the differences from other embodiments.

[0040] The scope of protection of this application is not limited to the embodiments described above. Obviously, those skilled in the art can make various modifications and variations to this disclosure without departing from the scope and spirit of this disclosure. If such modifications and variations fall within the scope of the methods disclosed herein and their equivalents, then the intent of this disclosure also includes such modifications and variations.

Claims

1. An integrated device for simmering, cooling, sample introduction, and imaging of traditional Chinese medicine components using microfluidic chips, characterized in that, include: It includes a medicine-simmering module, a cooling module, a sample injection module, and an imaging module. Each module is controlled as a whole via a control panel. The control panel features a seven-segment digital temperature display and switches, including a medicine-simmering switch, a cooling switch, a solenoid valve switch, and an imaging switch, corresponding to the medicine-simmering module, cooling module, sample injection module, and imaging module, respectively. When a switch is turned on, it drives the corresponding module to operate. The cooling switch includes a first peristaltic pump adjustment knob and a second peristaltic pump adjustment knob. The herbal simmering module is used to heat and simmer Chinese herbal medicine samples. It includes a support rod, a support structure, a cross clamp, a crab claw clamp, a high-frequency induction circuit board, a cooling fan, high-temperature ceramic terminals, an iron core, a copper core coil, a screw-top spherical reaction flask, and a small iron bowl. When the simmering switch on the control panel is turned on, the module begins operation. The support rod is fixed to the support structure, and the cross clamp and crab claw clamp support and adjust the position of the high-frequency induction circuit board, cooling fan, copper core coil, screw-top spherical reaction flask, and small iron bowl of the simmering module. The high-frequency induction circuit board is... The iron core is fixed to one side of the support rod and connected to the copper core coil, which is wound around the outside of the iron core. When the high-frequency induction circuit board is working, it drives the cooling fan to start. The iron core, as a heat-conducting and induction heating component, generates a magnetothermal eddy current effect and heats up rapidly. One end of the iron core is connected to a high-temperature ceramic terminal, and the other end of the iron core is fixed to the iron bowl. The iron bowl and the iron core are in thermal contact, which conducts the heat generated by the iron core to the internal space of the iron bowl. The screw-top spherical reaction bottle is placed inside the iron bowl. The screw-top spherical reaction bottle is used to hold the Chinese medicine sample and the water for simmering. The cooling module is used to condense and cool the steam containing Chinese herbal ingredients generated during the simmering process and to provide Chinese herbal liquid to the sample injection module. Specifically, it includes a first peristaltic pump, a second peristaltic pump, a condenser tube, and a conical flask. The condenser tube is inclinedly fixed to the support structure by a crab claw clamp. The condenser tube has a condensate inlet W1, a condensate outlet W2, an upper port O1, and a lower port O2. The first peristaltic pump is connected to the W1 and W2 ports of the condenser tube and is controlled by the first peristaltic pump adjustment knob on the control panel. It continuously delivers condensate into the condenser tube through the condensate inlet W1. The condensate flows into the conical flask from the lower port O2 of the condenser tube for collection and temporary storage. The sample introduction module is used to introduce the traditional Chinese medicine solution into the microfluidic chip for analysis. Specifically, it includes an X-axis displacement stage, a Y-axis displacement stage, a microfluidic chip mounting stage, and the microfluidic chip itself. The X-axis and Y-axis displacement stages are mounted on a support structure, and each stage has a microfluidic chip mounting stage for supporting the microfluidic chip. Several microfluidic chip mounting stages are arranged in a matrix to simultaneously hold multiple microfluidic chips. The X-axis and Y-axis displacement stages are used for fine adjustment of the two-dimensional position of the microfluidic chip in the horizontal direction. The imaging module is used to display the flow state and reaction process of the traditional Chinese medicine liquid in the microfluidic chip in real time. It includes a fixed frame, a Z-axis displacement stage, a chamfered frame, and a mobile terminal device. The fixed frame is placed on the support structure, the Z-axis displacement stage is located on the fixed frame, and the chamfered frame is set on the Z-axis displacement stage to fix the mobile terminal device.

2. The integrated device for simmering, cooling, sample introduction, and imaging of traditional Chinese medicine components for microfluidic chip analysis according to claim 1, characterized in that, The screw-top spherical reaction flask has a capacity of 50ml and is a three-necked flask. The three necks are A, B, and O. Cavity A is located at the center of the top of the screw-top spherical reaction flask and is the main vertical interface. Cavity B is an opening on the side of the screw-top spherical reaction flask that is angled upwards and forms a certain angle with Cavity A. Cavity O is a third opening on the side of the screw-top spherical reaction flask that is opposite to or at a certain angle to Cavity B, and its height is lower than that of Cavity B. When simmering the medicine, the Chinese medicine and simmering water are added through Cavity A, and the steam containing the Chinese medicine components will enter the cooling module through Cavity O.

3. The integrated device for simmering, cooling, sample introduction, and imaging of traditional Chinese medicine components for microfluidic chip analysis according to claim 1, characterized in that, When the high-frequency induction circuit board is working, it drives the copper core coil to generate a high-frequency induced electromagnetic field, which generates a magnetothermal eddy current effect in the iron core, causing the iron core and the iron bowl to heat up rapidly. The heat is evenly conducted through the iron bowl to the screw-top spherical reaction flask, and then transmitted to the seven-segment digital tube temperature display on the control panel for real-time monitoring via the temperature sensor.

4. The integrated device for simmering, cooling, sample introduction, and imaging of traditional Chinese medicine components for microfluidic chip analysis according to claim 1, characterized in that, The screw-top spherical reaction flask, condenser, conical flask, first peristaltic pump, and second peristaltic pump are connected by PVC tubing. The conical flask includes an O3 port, a C port, and a D port. The O3 port is connected to the lower O2 port of the condenser, the C port is connected to the second peristaltic pump, and the D port is connected to the microfluidic chip. The second peristaltic pump controls the pump rate via a knob on the control panel, increasing the pressure inside the conical flask. The liquid medicine inside the conical flask is then introduced from the D port through a four-way solenoid valve into the injection channel of the microfluidic chip in the injection module.

5. The integrated device for simmering, cooling, sample introduction, and imaging of traditional Chinese medicine components for microfluidic chip analysis according to claim 1, characterized in that, The herbal liquid processed by the cooling module is selectively introduced into the corresponding microfluidic chip under the control of the solenoid valve switch on the control panel, realizing independent sample introduction and switching between different chips.

6. The integrated device for simmering, cooling, sample introduction, and imaging of traditional Chinese medicine components for microfluidic chip analysis according to claim 1, characterized in that, The fixed mobile terminal device is equipped with a microscope lens and a magnifying glass to amplify, collect, and record the flow, diffusion, and reaction processes of the traditional Chinese medicine liquid within the microfluidic chip in real time, enabling intuitive observation of the analysis process.

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