Compound composition for strengthening primordial qi and promoting growth and preparation process thereof

Abstract

The invention provides a compound composition for cultivating primordial qi and promoting growth and a preparation process thereof, and the preparation process comprises the following steps: adding water into traditional Chinese medicine components, carrying out high-temperature extraction to obtain a basic water extract, and filtering and concentrating the basic water extract to obtain a concentrated water extract; adding a compound enzyme into the concentrated water extract for enzymolysis to obtain an enzymatic hydrolysate, adding diatomite into the enzymatic hydrolysate for targeted adsorption and filtration to obtain a primary filtrate, cooling the primary filtrate to room temperature, adding acid to adjust the pH value to 5.8-6.2, and adding a xanthan gum water solution to obtain a traditional Chinese medicine water extract; adding a bacterial suspension into the traditional Chinese medicine water extract to obtain a traditional Chinese medicine compound liquid, wherein the bacterial suspension contains inactivated lactobacillus helveticus CCFM1263; mixing bone collagen peptide and casein phosphopeptide to obtain a mixture, and dissolving the mixture in purified water in which sodium citrate is dissolved in advance to obtain a peptide premixed solution; slowly adding the peptide premixed liquid into the traditional Chinese medicine composite liquid, fully mixing, filtering and sterilizing to obtain the compound composition for cultivating the primordial qi and promoting growth.

Description

A compound composition for promoting growth and its preparation process Technical Field

[0001] This invention relates to the field of compositions, and in particular to a compound composition for promoting growth and development and its preparation process. Background Technology

[0002] Growth retardation or poor development in children is a significant issue in the field of child health. It not only affects children's physical development but may also have long-term impacts on their psychological growth and future health. There is an urgent need for safe, effective intervention programs that are tailored to children's physiological characteristics.

[0003] Current interventions for children with growth retardation or poor development have significant limitations: on the one hand, simple calcium supplementation focuses on supplementing a single nutrient, neglecting the complex physiological mechanisms of calcium absorption and utilization in the human body, making it difficult to fundamentally meet the comprehensive needs of children's growth and development; on the other hand, while growth hormone drugs have certain effects under specific medical conditions, they are subject to strict restrictions on the applicable population, dosage, and duration of use, preventing their widespread application in children and posing potential risks.

[0004] From a physiological perspective, children's organ development is characterized by "excess in the liver and heart, deficiency in the spleen and lungs, and weakness in the kidneys." Kidney deficiency is a significant cause of developmental delays and bedwetting in children, requiring targeted treatment. Modern medical research also indicates that normal height growth in children is regulated by multiple factors, with genetics accounting for approximately 60%-80%. Other factors closely related to endocrine function, nutrition, exercise intensity, and sleep quality also play a role. This necessitates a multi-dimensional and comprehensive approach to intervening in children's height development.

[0005] While traditional Chinese medicine (TCM) offers various kidney-tonifying and calming formulas, such as combinations of oyster shell, dragon bone, and Sichuan pepper, or kidney-tonifying and calming drugs containing active substances like jujube seed saponins, lily total saponins, and deer antler extract, these formulas are primarily designed for adult symptoms like insomnia, forgetfulness, dizziness, and tinnitus caused by kidney deficiency. They fail to adequately consider the physiological development and nutritional needs of children, lacking specific nutritional fortification ingredients tailored to children's growth and development. Therefore, they cannot simultaneously achieve the dual effects of strengthening the kidneys and calming the mind, as well as aiding sleep and promoting growth. Furthermore, traditional TCM compound formulations face key technological bottlenecks in their preparation processes: the complex composition of TCM aqueous extracts, containing various charged polysaccharides, proteins, tannins, etc., readily undergoes charge neutralization reactions when combined with oppositely charged nutritional fortification ingredients (such as peptides), forming flocculent precipitates. This not only severely affects the uniformity and stability of the product but also reduces the bioavailability of the active ingredients, hindering the application and development of TCM compound formulations in the field of children's growth intervention.

[0006] Therefore, there is an urgent need to develop a composition for children that has the functions of strengthening the kidneys and calming the mind, helping sleep, and thus promoting growth and development. Summary of the Invention

[0007] The purpose of this invention is to provide a compound composition for nourishing the body and promoting growth, and its preparation process, especially for children, which can strengthen the kidneys, calm the mind, and help with sleep, thereby achieving the effect of nourishing the body and promoting growth.

[0008] To achieve the above objectives, this technical solution provides a preparation process for a compound composition for nourishing and promoting growth, comprising the following steps: S1: Adding water to the traditional Chinese medicine components for high-temperature extraction to obtain a basic aqueous extract, filtering and concentrating the basic aqueous extract to obtain a concentrated aqueous extract; S2: Adding a compound enzyme to the concentrated aqueous extract for enzymatic hydrolysis to obtain an enzymatic hydrolysate, adding diatomaceous earth to the enzymatic hydrolysate for targeted adsorption and filtration to obtain a primary filtrate, cooling the primary filtrate to room temperature, adjusting the pH to 5.8-6.2 with acid, and then adding xanthan gum aqueous solution to obtain a traditional Chinese medicine aqueous extract; S3: Adding a bacterial suspension to the traditional Chinese medicine aqueous extract to obtain a traditional Chinese medicine compound solution, wherein the bacterial suspension contains inactivated Lactobacillus helveticus CCFM1263; S4: Mixing bone collagen peptides and casein phosphopeptides to obtain a mixture, dissolving the mixture in purified water pre-dissolved with sodium citrate to obtain a peptide premix; S5: Slowly adding the peptide premix to the traditional Chinese medicine compound solution, mixing thoroughly, filtering and sterilizing to obtain the compound composition for nourishing and promoting growth.

[0009] Unlike traditional compound compositions that simply mix all active ingredients and add thickeners, the preparation process of the growth-promoting compound composition provided in this solution utilizes active control of the Zeta potential to regulate the final growth-promoting compound composition to less than -25mV. The Zeta potential of the growth-promoting compound composition prepared in this solution is stabilized at around -30mV. At this point, a strong electrostatic repulsion is formed between particles, which can effectively overcome van der Waals attraction. This completely solves the problem that when traditional processes rely solely on xanthan gum and single electrostatic repulsion, submicron particles such as liposomes / micelles in the system are prone to slow aggregation and stratification during long-term storage or temperature changes. This greatly extends the shelf life and safety of the growth-promoting compound composition.

[0010] Regarding step S1 of this plan: The Chinese herbal ingredients mentioned in step S1 include 10 kinds of Chinese herbal ingredients, including Polygonatum sibiricum, Ziziphus jujuba var. spinosa, Lycium barbarum, Longan aril, Nelumbo nucifera, Dioscorea opposita, Poria cocos, Morus alba, Citrus reticulata peel and Glycyrrhiza uralensis.

[0011] Specifically, the Chinese herbal ingredients in this formula are carefully selected from ten herbs: Polygonatum sibiricum, Ziziphus jujuba var. spinosa, Lycium barbarum, Longan aril, Nelumbo nucifera, Dioscorea opposita, Poria cocos, Morus alba, Citrus reticulata peel, and Glycyrrhiza uralensis. The core principle is based on the special physiological characteristics of children, who often have excess liver and heart, deficient spleen and lung, and weak kidney. This formula aims to meet the core needs of nourishing the body and promoting growth, while avoiding the shortcomings of children's delicate spleen and stomach and low tolerance. It achieves a balance between precise efficacy and safe and gentle medication.

[0012] From the perspective of traditional Chinese medicine mechanisms, the herbal components provided in this formula are Polygonatum sibiricum and Ziziphus jujuba var. spinosa as the principal ingredients, which nourish the innate constitution and calm the mind. The core functions of Polygonatum sibiricum are to replenish qi and nourish yin, strengthen the spleen, moisten the lungs, and benefit the kidneys. It can not only nourish the innate kidney qi and provide the original driving force for growth and development, but also nourish the yin of the spleen and lungs, making up for the shortcomings of "spleen and lung deficiency" in children, and avoiding the impact of weak organ function on nutrient absorption and qi and blood generation. Ziziphus jujuba var. spinosa has the core functions of calming the mind and nourishing the heart and liver. Ziziphus jujuba var. spinosa is neutral in nature and non-toxic. It can not only soothe the restless mind of children and relieve problems such as crying at night and difficulty falling asleep, but also indirectly assist the nourishment of kidney qi by nourishing liver blood (the liver stores blood, the kidney stores essence, and essence and blood have the same origin). Moreover, the sour taste can astringe and consolidate, which can help improve nocturnal enuresis caused by "frequent kidney deficiency".

[0013] The herbal ingredients provided in this formula, with wolfberry, longan pulp, and lotus seeds as supporting ingredients, gently nourish and harmonize the heart and kidneys. The core function of wolfberry is to nourish the liver and kidneys, benefit essence and improve eyesight, as children often suffer from kidney deficiency. It easily affects the liver meridian, which is related to the liver and kidneys, leading to insufficient liver blood and impaired vision development. At the same time, wolfberries can enhance the kidney-tonifying power of polygonatum, and its medicinal properties are mild and gentle, without the drawbacks of being greasy or cloying, making it suitable for children with low spleen and stomach tolerance and avoiding indigestion caused by tonification. Longan pulp is effective in tonifying the heart and spleen, nourishing blood and calming the mind. Longan pulp is sweet and warm without being drying. It can nourish the spleen and enhance the ability to generate qi and blood, providing a material basis for growth and development. It can also work with jujube seed to calm the mind and improve problems such as shallow sleep and easy awakening caused by insufficient qi and blood in children. Moreover, its sweetness is natural and more easily accepted by children. Lotus seeds are effective in tonifying the spleen and stopping diarrhea, tonifying the kidneys and astringing essence, nourishing the heart and calming the mind. Tonifying the spleen can enhance the digestive function of children's spleen and stomach, improving "frequent spleen deficiency". Tonifying the kidneys and astringing essence can help strengthen the kidneys and relieve bedwetting at night. Nourishing the heart and calming the mind can enhance the sleep-aiding effect of jujube seed.

[0014] The herbal ingredients provided in this formula include yam, poria cocos, mulberry, and tangerine peel as adjuvants, which promote digestion and prevent greasiness. Yam's effects include tonifying qi and nourishing yin, as well as strengthening the spleen, lungs, and kidneys. It can enhance the digestive function of the spleen and stomach, improve indigestion and loss of appetite caused by "frequent spleen deficiency," and nourish the yin of the lungs and kidneys. Together with polygonatum and wolfberry, it strengthens the "vital energy" (qi). Efficacy: Poria cocos is effective in promoting diuresis and eliminating dampness, strengthening the spleen and calming the mind. Poria cocos is mild and diuretic, which can strengthen the spleen and remove dampness without damaging the body's vital energy. At the same time, its calming effect can assist the sour jujube seed and longan pulp in calming the mind. Moreover, its medicinal properties are mild and have no greasy side effects. It can harmonize the sweet and warm nourishing properties of the principal and assistant herbs and avoid "nourishing and causing dampness". Mulberry is effective in nourishing yin and blood, generating fluids and moisturizing dryness. Mulberry moisturizes and replenishes fluids and prevents night sweats. At the same time, it can assist wolfberry and polygonatum in nourishing the liver and kidneys and providing yin and blood support for growth and development. Tangerine peel is effective in regulating qi and strengthening the spleen, drying dampness and resolving phlegm. Tangerine peel is pungent, warm and aromatic. It can regulate qi and strengthen the spleen, awaken the spleen and stimulate appetite, eliminate the greasy side effects, and promote the absorption of nutrients by the spleen and stomach. Its dampness-drying and phlegm-resolving effects can also relieve mild cough and phlegm problems caused by "lung deficiency" in children. Moreover, its pungent and warm properties are mild and will not deplete the child's vital energy in regulating qi.

[0015] The Chinese herbal ingredients provided in this plan use licorice as the guiding herb, which is sweet and mild, harmonizing and protecting the middle jiao (middle burner). Licorice can moderate the pungent and dispersing nature of tangerine peel and the cold nature of mulberry, and harmonize the sweet and warm nature of polygonatum and longan pulp, avoiding excessive stimulation of children's internal organs by a single herb. In addition, licorice can invigorate qi and replenish the middle jiao, enhance children's spleen and stomach function, make up for the deficiency of "spleen deficiency", and its sweet taste can moderate the stimulation of the gastrointestinal tract by the medicine, reduce discomfort such as abdominal pain and bloating, which is in line with the delicate physiological characteristics of children's spleen and stomach.

[0016] As mentioned above, the Chinese herbal ingredients provided in this solution are all of a "neutral" nature, with a mild overall medicinal property. They do not contain any strong tonics or aggressive ingredients, which perfectly match the physiological characteristics of children's delicate internal organs and underdeveloped physical constitution. From "nourishing the innate kidney qi" to "strengthening the acquired spleen and stomach" and then to "calming the mind and promoting sleep to promote growth," the Chinese herbal ingredients form a closed loop of efficacy of "nourishing the innate - nourishing the acquired - regulating sleep," which precisely matches the needs of children's growth and development that require the coordinated regulation of multiple factors.

[0017] In some embodiments, the traditional Chinese medicine components include 10 kinds of traditional Chinese medicine ingredients by weight, including 200-300 parts of Polygonatum sibiricum, 100-200 parts of Ziziphus jujuba var. spinosa, 60-100 parts of Lycium barbarum, 60-100 parts of Longan aril, 60-100 parts of Nelumbo nucifera, 60-100 parts of Dioscorea opposita, 60-100 parts of Poria cocos, 60-100 parts of Morus alba, 40-100 parts of Citrus reticulata peel, and 10-60 parts of Glycyrrhiza uralensis.

[0018] In step S1, 6-10 times the amount of water is added to the traditional Chinese medicine components, and the mixture is extracted multiple times at 85-100℃ to obtain a basic aqueous extract, with each extraction lasting 1-2 hours. The key active ingredients in the traditional Chinese medicine components are mostly water-soluble or thermally stable substances. The high temperature of 85-100℃ can disrupt the cell wall structure of the traditional Chinese medicine, accelerating the release of active ingredients from the cells into the aqueous solution, while also preventing the decomposition and inactivation of some heat-sensitive components due to excessively high temperatures; and the 6-10 times water addition provides sufficient dissolution medium.

[0019] Preferably, the basic aqueous extract is obtained by adding 6 to 10 times the amount of water to the herbal components and then extracting multiple times at 90±2℃. Temperature control at 90±2℃ avoids the herbal properties from becoming too hot or dry due to excessive extraction temperature, and also reduces the potential residual astringent properties from low-temperature extraction, ensuring the extract has a mild medicinal effect.

[0020] In some embodiments, the basic extract is subjected to primary filtration and fine filtration and vacuum concentration to obtain a concentrated aqueous extract.

[0021] Furthermore, the basic extract is initially filtered through a 200-mesh sieve and then finely filtered through a 0.45μm microporous membrane. Subsequently, it is concentrated under vacuum to obtain a concentrated aqueous extract with a specific gravity of 1.10-1.15.

[0022] It should be noted that the concentrated water extract contains a variety of positively charged (such as certain proteins and alkaloids) and negatively charged (such as polysaccharides, tannins, and organic acids) molecules. These positive and negative charges neutralize each other, making the zeta potential of the concentrated water extract close to zero.

[0023] Regarding step S2 of this scheme: Step S2 of this scheme involves adding a compound enzyme to the concentrated aqueous extract for enzymatic hydrolysis to obtain an enzymatic hydrolysate. The purpose is to hydrolyze the large molecules of starch and pectin that cause the liquid to become viscous and tend to settle to the bottom later, converting them into small molecules of sugar that are not easily aggregated. Then, diatomaceous earth is added to the enzymatic hydrolysate for targeted adsorption and filtration to obtain a primary filtrate to quickly remove some tannins, pigments, and unstable large molecules of colloids. Finally, pre-stabilization treatment is carried out by adjusting the acidity and adding xanthan gum aqueous solution.

[0024] Specifically, this scheme employs a rapid adsorption process using a combination of amylase and pectinase with diatomaceous earth to actively remove large molecular colloids and easily precipitated substances that cause subsequent stratification, rather than passively processing them later, thus reducing system instability from the source. The initial filtrate is cooled to room temperature, the pH is adjusted to 5.8-6.2, and then xanthan gum, a stabilizer, is added. The solution is dissolved under gentle stirring to obtain the herbal extract. This scheme utilizes xanthan gum as a linear polysaccharide, providing steric hindrance through the formation of a hydration layer and weak electrostatic repulsion.

[0025] In some embodiments, the complex enzyme contains amylase and pectinase. Further, based on 1000 parts of concentrated aqueous extract, the complex enzyme contains 3-5 parts of amylase and 6-8 parts of pectinase.

[0026] It should be noted that the Chinese herbal ingredients, such as yam, poria cocos, and polygonatum, all contain a certain amount of starch. This starch dissolves into the extract during water extraction, increasing the viscosity of the concentrated extract. Amylase can hydrolyze large starch molecules into smaller molecules such as glucose and maltose, completely destroying the colloidal structure of starch and significantly reducing the viscosity of the extract. This avoids problems such as uneven mixing and filter blockage caused by excessive viscosity in subsequent processes. If the starch is not removed, it is prone to local aggregation when compounded with peptides, xanthan gum, and other components, exacerbating the risk of precipitation caused by charge neutralization and affecting product stability. The hydrolyzed small-molecule sugars are more easily absorbed by children's spleen and stomach, without increasing the digestive burden, which aligns with the physiological characteristics of children's "frequent spleen deficiency."

[0027] The cell walls and intercellular matrix of traditional Chinese medicine raw materials contain a large amount of pectin. This substance has strong hydrophilicity and colloidal properties, and it forms a stable colloidal network in the aqueous extract. It is intertwined with polysaccharides, proteins and other substances, which is an important reason for subsequent layering and precipitation. Pectinase can specifically break the glycosidic bonds of pectin molecules, degrading them into small molecules such as galacturonic acid, and destroying the colloidal network formed by pectin. This exposes unstable macromolecules (such as some proteins and tannins) hidden in the pectin, making it easier for them to be targeted and removed by diatomaceous earth. After the pectin is degraded, the uniformity of the extract is significantly improved, avoiding the aggregation of effective ingredients and impurities caused by the "binding effect" of pectin. At the same time, it reduces the difficulty of subsequent pH adjustment and potential control, ensuring that the zeta potential can be accurately and stably maintained in the target range.

[0028] In some embodiments, a complex enzyme is added to the concentrated aqueous extract and incubated at 50-60°C for 20-40 minutes to obtain an enzymatic hydrolysate.

[0029] In addition, after obtaining the enzymatic hydrolysate, this method involves adding diatomaceous earth for targeted adsorption and immediately filtering it using a plate and frame filter press to obtain the initial filtrate. The initial filtrate is clear and has a zeta potential close to -10mV. It should be noted that because the initial filtrate mainly contains negatively charged polysaccharides and organic acids, its zeta potential is stably biased towards a negative value.

[0030] In some embodiments, based on 1000 parts of concentrated water extract, 1 to 3 parts of diatomaceous earth are added to the enzymatic hydrolysate at 55 to 65°C for targeted adsorption.

[0031] In some embodiments, after cooling the initial filtrate to room temperature, citric acid is added to adjust the pH to 5.8-6.2. Subsequently, xanthan gum aqueous solution is added to the acidified solution to obtain a traditional Chinese medicine aqueous extract. The zeta potential of the traditional Chinese medicine aqueous extract obtained in this scheme is close to -20mV. This is because xanthan gum is a linear polysaccharide with a strong negative charge, and its addition is equivalent to introducing a large amount of negative charge into the system.

[0032] In some embodiments, the xanthan gum aqueous solution is obtained by dissolving 1 to 4 parts of xanthan gum in 18 to 22 parts of water. Preferably, the xanthan gum aqueous solution is obtained by dissolving 2 parts of xanthan gum in 20 parts of water.

[0033] It should be noted that the pH value of the acidified material is far from the isoelectric point of most proteins, reducing the tendency to precipitate and ensuring that the peptides and traditional Chinese medicine ingredients added later carry the same negative charge, thereby generating electrostatic repulsion.

[0034] Regarding step S3 of this scheme: The bacterial suspension in this scheme contains inactivated Lactobacillus helveticus CCFM1263. Specifically, the bacterial suspension contains extracellular polysaccharides on the surface of inactivated Lactobacillus helveticus CCFM1263. Inactivated Lactobacillus helveticus CCFM1263 and its surface EPS carry a strong negative charge; therefore, their addition is equivalent to introducing a large amount of natural anionic polyelectrolytes into the system, which will significantly increase the negative charge density of the system. Correspondingly, the zeta potential of the traditional Chinese medicine compound solution is below -25mV, preferably -35mV.

[0035] In some embodiments, inactivated Lactobacillus helveticus CCFM1263 in powder form containing extracellular polysaccharides is slowly added to water at room temperature and gently stirred using a magnetic stirrer to obtain a bacterial suspension.

[0036] Furthermore, after gentle stirring at a stirring rate of 250-350 rpm for 15-25 minutes, the solution is added to water at 22-26°C. Preferably, after gentle stirring at a stirring rate of 300 rpm for 20 minutes, the solution is added to water at 25°C. During the dissolution process, the inactivated Lactobacillus helveticus CCFM1263 cells are fully wetted, causing the extracellular polysaccharides on their surface to slowly dissolve and be released into the water, forming a viscous bacterial suspension rich in extracellular polysaccharides.

[0037] In some embodiments, 2-6 parts of inactivated Lactobacillus helveticus CCFM1263 are added to 18-22 parts of water to obtain a bacterial suspension.

[0038] As mentioned earlier, the introduction of inactivated Lactobacillus helveticus CCFM1263 into the compound composition for promoting growth and vitality in this scheme can synergistically regulate the zeta potential to solidify the long-term stability of the system. Both inactivated Lactobacillus helveticus CCFM1263 and its surface-attached extracellular polysaccharides (EPS) are strongly negatively charged. After being added to the system, they work synergistically with xanthan gum to stabilize the zeta potential below -25mV. This high absolute negative potential can form a strong electrostatic repulsion, effectively overcoming the van der Waals attraction between colloidal particles of traditional Chinese medicine and peptide components, avoiding flocculent precipitation caused by charge neutralization, and solving the problem of slow aggregation of submicron particles such as liposomes / micelles under long-term storage or temperature changes in traditional processes. Moreover, the EPS on the surface of the strain is a negatively charged long-chain polymer with both hydrophilic and hydrophobic regions. It can be "anchored" to the surface of peptide components and the hydrophobic regions of colloidal particles of traditional Chinese medicine through hydrophobic interactions or hydrogen bonds, forming a dense hydrated steric hindrance layer.

[0039] In addition, Lactobacillus helveticus CCFM1263 itself is a solid microparticle with a size of 1-10 micrometers. They are uniformly dispersed in the liquid and can physically hinder the sedimentation path of other nanoscale particles, which is equivalent to adding countless "tiny roadblocks" to the system and slowing down the sedimentation rate.

[0040] Step S4 of this scheme: Take 5-20 parts of collagen peptide and 0.5-3 parts of casein phosphopeptide to obtain a mixture, and dissolve the mixture in 30-60 parts of purified water pre-dissolved with 0.1-0.2 parts of sodium citrate to obtain a peptide premix solution. This peptide premix solution can provide a stable ionic environment.

[0041] Collagen peptides and casein phosphopeptides, as small-molecule bioactive peptides, are susceptible to structural instability due to fluctuations in ionic strength and pH. Direct addition to complex aqueous extracts of traditional Chinese medicine can lead to peptide bond breakage, polymerization, or denaturation due to the presence of cations and anions carried by polysaccharides and tannins, resulting in loss of bioactivity. However, the stable ionic environment created by sodium citrate buffers external ionic strength changes, providing a suitable environment for peptides and ensuring their structural integrity and activity. Furthermore, peptides themselves carry a weak positive charge, while the pre-stabilized aqueous extracts of traditional Chinese medicine exhibit a negative charge (pH 5.8–6.2). This stable ionic environment buffers charge impacts, and the anions of sodium citrate gently interact with the weak positive charge on the peptide surface, preventing rapid charge neutralization between the peptides and the medicinal components, reducing flocculent precipitation, and ensuring the system's Zeta potential remains stable within a suitable range of approximately -30 mV.

[0042] In addition, collagen peptides are the core structural building blocks for bone and muscle growth, directly providing material support for children's growth and development; casein phosphopeptides can specifically bind to minerals such as calcium and iron, promoting their absorption and utilization, avoiding the problem of supplementation without absorption. A slightly higher dosage of casein phosphopeptides also ensures that collagen peptides and the minerals contained in traditional Chinese medicine are fully absorbed, forming a synergistic effect.

[0043] Regarding step S5 of this scheme: In the main mixing tank, stir the pre-stabilized herbal compound solution treated in step S3 at a medium speed (500-800 rpm). Slowly add the peptide premix prepared in S4 using a thin stream or dropwise. After all the solution has been added, continue stirring for 20-30 minutes to ensure complete homogenization. Adjust the volume to 1000 parts by water, filter through a 200-mesh sieve, and then pasteurize. Measure the zeta potential using laser Doppler electrophoresis; at this point, the zeta potential is -30 mV. Collagen peptides, casein phosphopeptides, etc., are positively charged; upon addition, they will partially neutralize the negatively charged system, causing a decrease in the absolute value of the zeta potential.

[0044] In step S5 of this scheme, the peptide premix is ​​added to the traditional Chinese medicine compound solution by a thin stream or dropwise at a stirring speed of 500~800 rpm and stirred for 20~30 minutes until fully mixed.

[0045] In some embodiments, after thorough mixing, the mixture is filtered through a 200-mesh sieve and then pasteurized to obtain a compound composition for promoting growth and vitality.

[0046] It should be noted that the Zeta potential of the final compound composition for promoting growth and health obtained by this method is -30mV. The higher the absolute value of the Zeta potential, the stronger the electrostatic repulsion between particles, and the more the system tends to be stably dispersed, resisting aggregation and stratification. This solves the problem that relying solely on xanthan gum and electrostatic repulsion, especially the tendency of submicron particles such as liposomes / micelles in the system to slowly aggregate under long-term storage or temperature changes.

[0047] This solution provides a compound composition for promoting growth and vitality, which is prepared according to the above-mentioned preparation process for the compound composition for promoting growth and vitality.

[0048] This growth-promoting compound contains concentrated water extract, collagen peptides, casein phosphopeptides, inactivated Lactobacillus helveticus CCFM1263, citric acid, xanthan gum, and water.

[0049] Furthermore, the concentrated aqueous extract contains 10 kinds of traditional Chinese medicine ingredients, including Polygonatum sibiricum, Ziziphus jujuba var. spinosa, Lycium barbarum, Longan aril, Nelumbo nucifera, Dioscorea opposita, Poria cocos, Morus alba, Citrus reticulata peel, and Glycyrrhiza uralensis.

[0050] Furthermore, the concentrated aqueous extract contains, by weight, 200-300 parts of Polygonatum sibiricum, 100-200 parts of Ziziphus jujuba var. spinosa, 60-100 parts of Lycium barbarum, 60-100 parts of Longan aril, 60-100 parts of Nelumbo nucifera, 60-100 parts of Dioscorea opposita, 60-100 parts of Poria cocos, 60-100 parts of Morus alba, 40-100 parts of Citrus reticulata peel, and 10-60 parts of Glycyrrhiza uralensis.

[0051] In some embodiments, the growth-promoting compound composition comprises, by weight, 300-600 parts of concentrated aqueous extract, 5-20 parts of collagen peptide, 0.5-3 parts of casein phosphopeptide, 2-6 parts of inactivated Lactobacillus helveticus CCFM1263, 2-6 parts of citric acid, 1-4 parts of xanthan gum, and 361-689.5 parts of water, and the total number of parts of the growth-promoting compound composition is 1000 parts.

[0052] Compared with existing technologies, this technical solution has the following characteristics and beneficial effects: The compound composition for nourishing and promoting growth provided by this solution is made from 10 kinds of traditional Chinese medicine, such as Polygonatum sibiricum and Ziziphus jujuba var. spinosa. It follows the classic compatibility logic of monarch, minister, assistant and guide, and is in line with the physiological characteristics of children, such as "liver and heart are often in excess, spleen and lungs are often deficient, and kidneys are often weak". It is specifically adapted to the needs of children's growth and development for multi-factor synergistic regulation. In addition, on the basis of traditional Chinese medicine compound, it is compounded with modern nutritional components such as bone collagen peptides and casein phosphopeptides, which not only exert the conditioning effect of traditional Chinese medicine for nourishing and promoting growth, but also provide growth raw materials, promote mineral absorption and assist sleep through nutritional components.

[0053] More importantly, the preparation method of the nourishing and growth-promoting compound composition provided in this solution abandons the traditional crude method of simple mixing and adding thickeners. Through enzymatic pretreatment, pH adjustment, and the synergistic effect of xanthan gum and inactivated Lactobacillus helveticus CCFM1263, the zeta potential of the product is stabilized at around -30mV. This fundamentally solves the problems of charge neutralization and particle aggregation when compounding Chinese herbal extracts with peptides and other components, thereby improving the long-term storage stability of the final product. Attached Figure Description

[0054] Figure 1 is a product image of the compound composition for nourishing and promoting growth prepared according to this method. Detailed Implementation

[0055] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention are within the scope of protection of the present invention.

[0056] Experiment: Example 1: Step S1: Take 263 parts of Polygonatum sibiricum, 133 parts of Ziziphus jujuba var. spinosa, 87 parts of Lycium barbarum, 87 parts of Longan aril, 87 parts of Nelumbo nucifera, 87 parts of Dioscorea opposita, 87 parts of Poria cocos, 87 parts of Morus alba, 53 parts of Citrus reticulata peel, and 3 parts of Glycyrrhiza uralensis as a traditional Chinese medicine composition. Add 8 times the amount of water to the traditional Chinese medicine composition for concentration and extraction to obtain a basic aqueous extract. Extract twice at 90±2℃, 1.5 hours each time. Then filter the basic aqueous extract using a 200-mesh sieve and a 0.45μm microporous membrane for fine filtration, and vacuum concentrate to a specific gravity of 1.10-1.15 (measured at 60℃) to obtain a concentrated aqueous extract; Step S2: Take 1000 parts of the concentrated aqueous extract Add a compound enzyme (4 parts amylase, 7 parts pectinase), incubate at 55℃ for 30 minutes to obtain enzymatic hydrolysate. After enzymatic hydrolysis, add 2 parts food-grade diatomaceous earth to the hydrolysate at 60℃ for adsorption and immediately filter using a plate and frame filter to obtain a clear initial filtrate. Take 600 parts of the initial filtrate, cool to room temperature, add 4 parts citric acid to adjust the pH to 5.8~6.2, take 2 parts xanthan gum, add 20 parts water, stir to dissolve, and add to the initial filtrate to obtain a traditional Chinese medicine aqueous extract; Step S3: Slowly add 4 parts powdered inactivated Lactobacillus helveticus CCFM1263 (containing extracellular polysaccharides) to 20 parts of water at 25°C and stir magnetically (300... Stir gently for 20 minutes at rpm to fully wet the bacteria, allowing the extracellular polysaccharides on their surface to slowly dissolve and release into the water, forming a viscous bacterial suspension rich in extracellular polysaccharides. This suspension is then added to the aqueous extract of traditional Chinese medicine to obtain a compound solution of traditional Chinese medicine. Step S4: Mix 10 parts of collagen peptide and 1 part of casein phosphopeptide, and dissolve them in a small amount of 40 parts of purified water at 25°C to obtain a peptide premix, wherein 0.1 parts of sodium citrate are pre-dissolved in this purified water. Step S5: Stir the compound solution of traditional Chinese medicine at medium speed (500-800 rpm) in the main mixing tank. Slowly add the peptide premix in a thin stream or dropwise manner, and continue stirring for 20-30 minutes after all the peptide premix has been added to ensure complete homogeneity. Adjust the volume to 1000 parts with water, filter through a 200-mesh sieve, and pasteurize to obtain a compound composition for nourishing and promoting growth.

[0057] Comparative Example 1: Step S1: Take 263 parts of Polygonatum sibiricum, 133 parts of Ziziphus jujuba var. spinosa, 87 parts of Lycium barbarum, 87 parts of Longan aril, 87 parts of Nelumbo nucifera, 87 parts of Dioscorea opposita, 87 parts of Poria cocos, 87 parts of Morus alba, 53 parts of Citrus reticulata peel, and 3 parts of Glycyrrhiza uralensis as a traditional Chinese medicine composition. Add 8 times the amount of water to the traditional Chinese medicine composition for concentration and extraction to obtain a basic aqueous extract. Extract twice at 90±2℃, 1.5 hours each time. Then filter the basic aqueous extract using a 200-mesh sieve for primary filtration and a 0.45μm microporous membrane for fine filtration. Vacuum concentration to a specific gravity of 1.10-1.15 (measured at 60℃) yields concentrated aqueous extract; Step S2: Take 600 parts of concentrated aqueous extract, cool to room temperature, add 4 parts of citric acid to adjust pH to 5.8-6.2, take 2 parts of xanthan gum, add to 20 parts of water, stir to dissolve, and then add to the initial filtrate to obtain the herbal aqueous extract; Step S3: Slowly add 4 parts of powdered inactivated Lactobacillus helveticus CCFM1263 (containing extracellular polysaccharides) to 20 parts of water at 25°C using magnetic stirring (300... Stir gently for 20 minutes at rpm to fully wet the bacteria, allowing the extracellular polysaccharides on their surface to slowly dissolve and release into the water, forming a viscous bacterial suspension rich in extracellular polysaccharides. This suspension is then added to the aqueous extract of traditional Chinese medicine to obtain a compound solution. Step S4: Mix 10 parts of collagen peptide and 1 part of casein phosphopeptide, and dissolve them in a small amount of 40 parts of purified water at 25°C to obtain a peptide premix, wherein 0.1 parts of sodium citrate are pre-dissolved in this purified water. Step S5: Stir the compound solution of traditional Chinese medicine at medium speed (500-800 rpm) in the main mixing tank. Add the peptide premix solution slowly in a thin stream or dropwise, and continue stirring for 20-30 minutes after all the solution has been added to ensure complete homogeneity. Make up to 1000 parts with water, filter through a 200-mesh sieve, and pasteurize to obtain the compound composition. Comparative Example 2: Step S1: Take 263 parts of Polygonatum sibiricum, 133 parts of Ziziphus jujuba var. spinosa, 87 parts of Lycium barbarum, 87 parts of Longan aril, 87 parts of Nelumbo nucifera, 87 parts of Dioscorea opposita, 87 parts of Poria cocos, 87 parts of Morus alba, 53 parts of Citrus reticulata peel, and 3 parts of Glycyrrhiza uralensis as a traditional Chinese medicine composition. Add 8 times the amount of water to the traditional Chinese medicine composition for concentration and extraction to obtain the basic aqueous extract. Extract twice at 90±2℃, 1 liter each time. After 5 hours, the basic aqueous extract was filtered through a 200-mesh sieve and a 0.45μm microporous membrane for fine filtration, and then vacuum concentrated to a specific gravity of 1.10-1.15 (measured at 60℃) to obtain a concentrated aqueous extract. Step S2: Take 1000 parts of the concentrated aqueous extract, add a compound enzyme (4 parts amylase and 7 parts pectinase), and incubate at 55℃ for 30 minutes to obtain an enzymatic hydrolysate. After enzymatic hydrolysis, add 2 parts of food-grade diatomaceous earth to the hydrolysate at 60℃ for adsorption and immediately filter through a plate and frame filter to obtain a clear primary filtrate. Take 600 parts of the primary filtrate, cool it to room temperature, and add 4 parts of citric acid to adjust the pH to 5.8-6.2. Take 2 parts xanthan gum, add 20 parts water, stir to dissolve, and then add to the initial filtrate to obtain the herbal extract; Step S3: Mix 10 parts collagen peptide and 1 part casein phosphopeptide, dissolve in a small amount of 40 parts 25℃ purified water to obtain a peptide premix, wherein 0.1 parts sodium citrate are pre-dissolved in this purified water; Step S4: Stir the herbal extract at medium speed (500-800 rpm) in the main mixing tank, slowly add the peptide premix in a thin stream or dropwise, and continue stirring for 20-30 minutes after all the peptide premix has been added to ensure complete homogeneity. Adjust the volume to 1000 parts with water, filter through a 200-mesh sieve, and pasteurize to obtain the compound composition.

[0058] Comparative Example 3: Step S1: Take 263 parts of Polygonatum sibiricum, 133 parts of Ziziphus jujuba var. spinosa, 87 parts of Lycium barbarum, 87 parts of Longan aril, 87 parts of Nelumbo nucifera, 87 parts of Dioscorea opposita, 87 parts of Poria cocos, 87 parts of Morus alba, 53 parts of Citrus reticulata peel, and 3 parts of Glycyrrhiza uralensis as a traditional Chinese medicine composition. Add 8 times the amount of water to the traditional Chinese medicine composition for concentration and extraction to obtain a basic aqueous extract. Extract twice at 90±2℃, 1.5 hours each time. Then filter the basic aqueous extract by primary filtration through a 200-mesh sieve and fine filtration through a 0.45μm microporous membrane, and vacuum concentrate to a specific gravity of 1.10-1.15 (measured at 60℃) to obtain a concentrated aqueous extract; Step S2: Take 1000 parts of the concentrated aqueous extract, Add a compound enzyme (4 parts amylase, 7 parts pectinase), incubate at 55℃ for 30 minutes to obtain an enzymatic hydrolysate. After enzymatic hydrolysis, add 2 parts food-grade diatomaceous earth to the hydrolysate at 60℃ for adsorption and immediately filter using a plate and frame filter to obtain a clear initial filtrate. Take 600 parts of the initial filtrate, cool it to room temperature, add 4 parts citric acid to adjust the pH to 5.8~6.2, take 2 parts xanthan gum, add 20 parts water, stir to dissolve, and add to the initial filtrate to obtain a traditional Chinese medicine aqueous extract; Step S3: Slowly add 4 parts powdered inactivated Lactobacillus helveticus CCFM1263 (containing extracellular polysaccharides) to 20 parts of water at 25°C and stir magnetically (300... Stir gently for 20 minutes at rpm to fully wet the bacteria, allowing the extracellular polysaccharides on their surface to slowly dissolve and release into the water, forming a viscous bacterial suspension rich in extracellular polysaccharides; Step S4: Mix 10 parts of collagen peptide and 1 part of casein phosphopeptide, and dissolve them in a small amount of 40 parts of 25°C purified water to obtain a peptide premix, wherein 0.1 parts of sodium citrate are pre-dissolved in this purified water; Step S5: Stir the herbal extract at medium speed (500-800 rpm) in the main mixing tank, slowly add the peptide premix in a thin stream or dropwise manner, and continue stirring for 20-30 minutes after all the addition is complete to ensure complete homogeneity and obtain the first mixture. Add the bacterial suspension to the first mixture and continue stirring for 20-30 minutes to ensure complete homogeneity. Adjust the volume to 1000 parts with water, filter through a 200-mesh sieve, and pasteurize to obtain the compound composition.

[0059] Comparative Example 4: Step S1: Take 263 parts of Polygonatum sibiricum, 133 parts of Ziziphus jujuba var. spinosa, 87 parts of Lycium barbarum, 87 parts of Longan aril, 87 parts of Nelumbo nucifera, 87 parts of Dioscorea opposita, 87 parts of Poria cocos, 87 parts of Morus alba, 53 parts of Citrus reticulata peel, and 3 parts of Glycyrrhiza uralensis as a traditional Chinese medicine composition. Add 8 times the amount of water to the traditional Chinese medicine composition for concentration and extraction to obtain a basic aqueous extract. Extract twice at 90±2℃, 1.5 hours each time. Then filter the basic aqueous extract using a 200-mesh sieve for primary filtration and a 0.45μm microporous membrane for fine filtration, and vacuum concentrate to a specific gravity of 1.10-1.15 (measured at 60℃) to obtain a concentrated aqueous extract; Step S2: Take 1000 parts of the concentrated aqueous extract, add compound... Synthetically synthesized enzymes (4 parts amylase, 7 parts pectinase) were incubated at 55°C for 30 minutes to obtain an enzymatic hydrolysate. After hydrolysis, 2 parts food-grade diatomaceous earth were added to the hydrolysate at 60°C for adsorption, and the mixture was immediately filtered through a plate and frame filter to obtain a clear initial filtrate. 600 parts of the initial filtrate were taken, cooled to room temperature, and 4 parts citric acid were added to adjust the pH to 5.8-6.2. 2 parts xanthan gum were added to 20 parts water, stirred and dissolved, and then added to the initial filtrate to obtain a traditional Chinese medicine aqueous extract. Step S3: 4 parts of powdered inactivated Lactobacillus helveticus CCFM1263 (with most of the extracellular polysaccharides removed) were slowly added to 20 parts of water at 25°C, and the mixture was magnetically stirred (300...). Stir gently for 20 minutes at rpm to fully wet the bacterial cells, then add to the herbal extract to obtain a herbal compound solution; Step S4: Mix 10 parts of collagen peptide and 1 part of casein phosphopeptide, dissolve in a small amount of 40 parts of 25℃ purified water to obtain a peptide premix, wherein 0.1 parts of sodium citrate are pre-dissolved in the purified water; Step S5: Stir the herbal compound solution at medium speed (500-800 rpm) in the main mixing tank, slowly add the peptide premix in a thin stream or dropwise manner, and continue stirring for 20-30 minutes after all the solution has been added to ensure complete homogeneity, dilute to 1000 parts with water, filter through a 200-mesh sieve and pasteurize to obtain the compound composition.

[0060] Comparative Example 5: Step S1: Take 263 parts of Polygonatum sibiricum, 133 parts of Ziziphus jujuba var. spinosa, 87 parts of Lycium barbarum, 87 parts of Longan aril, 87 parts of Nelumbo nucifera, 87 parts of Dioscorea opposita, 87 parts of Poria cocos, 87 parts of Morus alba, 53 parts of Citrus reticulata peel, and 3 parts of Glycyrrhiza uralensis as a traditional Chinese medicine composition. Add 8 times the amount of water to the traditional Chinese medicine composition for concentration and extraction to obtain a basic aqueous extract. Extract twice at 90±2℃, 1.5 hours each time. Then filter the basic aqueous extract by primary filtration through a 200-mesh sieve and fine filtration through a 0.45μm microporous membrane, and vacuum concentrate to a specific gravity of 1.10-1.15 (measured at 60℃) to obtain a concentrated aqueous extract; Step S2: Take 100 0 parts of concentrated aqueous extract were added to a compound enzyme (4 parts amylase and 7 parts pectinase) and incubated at 55°C for 30 minutes to obtain an enzymatic hydrolysate. After enzymatic hydrolysis, 2 parts of food-grade diatomaceous earth were added to the hydrolysate at 60°C for adsorption and immediately filtered through a plate and frame filter to obtain a clear initial filtrate. 600 parts of the initial filtrate were taken, cooled to room temperature, and 4 parts of citric acid were added to adjust the pH to 5.8-6.2. 2 parts of xanthan gum were added to 20 parts of water, stirred and dissolved, and then added to the initial filtrate to obtain a traditional Chinese medicine aqueous extract. Step S3: 4 parts of powdered microcrystalline cellulose were slowly added to 20 parts of water at 25°C, and magnetic stirring was used (300... Step S4: Mix 10 parts of collagen peptide and 1 part of casein phosphopeptide, and dissolve them in a small amount of 40 parts of 25°C purified water to obtain a peptide premix, wherein 0.1 parts of sodium citrate are pre-dissolved in the purified water; Step S5: Stir the traditional Chinese medicine compound solution at medium speed (500-800 rpm) in the main mixing tank, slowly add the peptide premix in a thin stream or dropwise manner, and continue stirring for 20-30 minutes after all the peptide premix has been added to ensure complete homogeneity. Make up the volume with water to 1000 parts, filter through a 200-mesh sieve, and pasteurize to obtain the nourishing and growth-promoting compound composition.

[0061] Test: Test Example 1, Potential Value Measurement: Laser Doppler electrophoresis was used to repeatedly measure the potential values ​​of each step in the preparation process of Example 1, Comparative Examples 1 to 5, and the final compound composition three times, and the average value was taken. The results are shown in Table 1 below: Table 1 Comparison of Potential Values ​​of Different Process Methods .

[0063] It should be noted that " / " indicates that this step does not involve potential measurement.

[0064] The meaning of the potential value is as follows: [Absolutely unstable region]: 0mV ± 5mV. Charge neutralization inevitably leads to flocculation and stratification.

[0065] [Metastability Region (Critical Point)]: |±5mV| to |±15mV|. A weak repulsive force begins to exist between particles, but it is insufficient to resist disturbances caused by long-term storage or external conditions (such as temperature changes or vibrations), making slow aggregation likely.

[0066] [Stability Region]: |±15mV| to |±25 mV|. There is moderate electrostatic repulsion between particles, allowing the system to maintain short- to medium-term stability.

[0067] [Suitable Stability Region]: Above |±25 mV|. Strong electrostatic repulsion exists between particles, effectively overcoming van der Waals attraction. The system tends to be highly stable and dispersed, exhibiting excellent resistance to aggregation and stratification.

[0068] Test Example 2, High-Temperature Accelerated Test: The compound compositions prepared in Example 1 and Comparative Examples 1 to 5 were placed in transparent test tubes and allowed to stand for a period of time. The precipitation was observed, and the Zeta potential values ​​were compared. The comparison results are shown in Table 2 below. Each compound composition was sealed in a 10mL test tube to reduce evaporation. The samples were stored at high temperature (40±2℃) for 30 days to observe the storage stability of the drinking liquid.

[0069] Table 2 Comparison of Indicators After Acceleration by Different Process Methods

[0070] Comparing the potential values ​​and precipitation of Example 1 and Comparative Examples 1-5 at 0d and 30d, it can be seen that Example 1 has the best performance in all indicators, indicating that the current process helps optimize the initial potential and can significantly maintain potential stability. After accelerated testing, Comparative Examples 1-5 showed a significant decrease in the absolute value of the Zeta potential and visible precipitation, indicating a deterioration in system stability. The results of Example 1 and Comparative Examples 2, 3, 4, and 5 show that early enzymatic hydrolysis to remove large starch and pectin molecules that tend to settle later can play a certain role. Furthermore, inactivated Lactobacillus helveticus CCFM1263 (containing extracellular polysaccharides) plays an irreplaceable role in physical stabilization in complex systems, forming a network with higher strength and better elasticity than xanthan gum alone, which is unmatched by other common raw materials. Furthermore, the order in which inactivated Lactobacillus helveticus CCFM1263 (containing extracellular polysaccharides) is added is also crucial. Adding it before the peptide is the best approach. This method allows it to intertwine and entangle with the xanthan gum network already present in the Chinese medicine base solution, establishing a "negative charge platform" first, thereby forming a more uniform and robust network throughout the entire system.

[0071] Those skilled in the art should understand that the technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments have been described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0072] The above embodiments are merely illustrative of several implementation methods of this application, and their descriptions are relatively specific and detailed, but they should not be construed as limiting the scope of this application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this application should be determined by the appended claims.

Claims

1. A preparation process for a compound composition for nourishing and promoting growth, characterized in that, Includes the following steps: S1: Water is added to the Chinese herbal medicine components and high temperature extraction is carried out to obtain a basic aqueous extract. The basic aqueous extract is then filtered and concentrated to obtain a concentrated aqueous extract. S2: Add a compound enzyme to the concentrated aqueous extract for enzymatic hydrolysis to obtain an enzymatic hydrolysate. Add diatomaceous earth to the enzymatic hydrolysate for targeted adsorption and filtration to obtain a primary filtrate. Cool the primary filtrate to room temperature, adjust the pH to 5.8-6.2 with acid, and then add xanthan gum aqueous solution to obtain a traditional Chinese medicine aqueous extract. S3: Add a bacterial suspension to the traditional Chinese medicine aqueous extract to obtain a traditional Chinese medicine compound solution, wherein the bacterial suspension contains inactivated Lactobacillus helveticus CCFM1263. S4: Mix collagen peptides and casein phosphopeptides to obtain a mixture. Dissolve the mixture in purified water pre-dissolved with sodium citrate to obtain a peptide premix. S5: Slowly add the peptide premix to the traditional Chinese medicine compound solution, mix thoroughly, filter, and sterilize to obtain a compound composition for nourishing and promoting growth.

2. The preparation process of the compound composition for nourishing and promoting growth according to claim 1, characterized in that, The zeta potential of the compound composition for nourishing and promoting growth is less than -25mV.

3. The preparation process of the compound composition for nourishing and promoting growth according to claim 1, characterized in that, The herbal ingredients include 10 kinds of Chinese medicinal ingredients, such as Polygonatum sibiricum, Ziziphus jujuba var. spinosa, Lycium barbarum, Longan aril, Nelumbo nucifera, Dioscorea opposita, Poria cocos, Morus alba, Citrus reticulata peel, and Glycyrrhiza uralensis.

4. The preparation process of the compound composition for nourishing and promoting growth according to claim 1, characterized in that, The herbal ingredients include 10 kinds of Chinese herbal components by weight: 200-300 parts of Polygonatum sibiricum, 100-200 parts of Ziziphus jujuba var. spinosa, 60-100 parts of Lycium barbarum, 60-100 parts of Longan aril, 60-100 parts of Nelumbo nucifera, 60-100 parts of Dioscorea opposita, 60-100 parts of Poria cocos, 60-100 parts of Morus alba, 40-100 parts of Citrus reticulata peel, and 10-60 parts of Glycyrrhiza uralensis.

5. The preparation process of the compound composition for nourishing and promoting growth according to claim 1, characterized in that, The bacterial suspension contains extracellular polysaccharides on the surface of inactivated Lactobacillus helveticus CCFM1263. Powdered inactivated Lactobacillus helveticus CCFM1263 containing extracellular polysaccharides is slowly added to room temperature water and gently stirred with a magnetic stirrer to obtain the bacterial suspension.

6. The preparation process of the compound composition for nourishing and promoting growth according to claim 1, characterized in that, Based on 1000 parts of concentrated water extract, the compound enzyme contains 3-5 parts of amylase and 6-8 parts of pectinase.

7. The preparation process of the compound composition for nourishing and promoting growth according to claim 1, characterized in that, Take 5-20 parts of collagen peptide and 0.5-3 parts of casein phosphopeptide and mix them to obtain a mixture. Dissolve the mixture in 30-60 parts of purified water that has been pre-dissolved with 0.1-0.2 parts of sodium citrate to obtain a peptide premix.

8. The preparation process of the compound composition for nourishing and promoting growth according to claim 1, characterized in that, At a stirring speed of 500-800 rpm, add the peptide premix to 300-600 parts of the traditional Chinese medicine compound solution by a thin stream or dropwise and stir for 20-30 minutes until fully mixed.

9. A compound composition for nourishing and promoting growth, characterized in that, The compound composition for nourishing and promoting growth is prepared according to the preparation process of any one of claims 1 to 8.

10. The compound composition for nourishing and promoting growth according to claim 9, characterized in that, It contains concentrated water extract, collagen peptides, casein phosphopeptides, inactivated Lactobacillus helveticus CCFM1263, citric acid, xanthan gum, and water.

Images