Room acceptance method and system for medical instrument department

Abstract

The invention provides a medical instrument department room acceptance method and system, and can be applied to the technical field of nuclear magnetic resonance and environment monitoring. The method comprises the following steps: injecting a nuclear magnetic resonance gas probe into a to-be-evaluated space by using a gas probe injector to form environmental disturbance of the nuclear magnetic resonance gas probe and the to-be-evaluated space; performing nuclear magnetic resonance data acquisition on the to-be-evaluated space by using a first nuclear magnetic resonance system arranged in the to-be-evaluated space to obtain a nuclear magnetic resonance spectrum sequence of each space unit; performing nuclear magnetic resonance diffusion weighted data acquisition on the to-be-evaluated space by using a second nuclear magnetic resonance system arranged in the to-be-evaluated space to obtain a diffusion weighted imaging sequence of each space unit in the to-be-evaluated space; and performing environment state evaluation on the to-be-evaluated space by using a processor based on the nuclear magnetic resonance spectrum sequence of each space unit in the to-be-evaluated space and the diffusion weighted imaging sequence of each space unit in the to-be-evaluated space to obtain an evaluation result.

Description

Technical Field

[0001] This disclosure relates to the fields of nuclear magnetic resonance and environmental monitoring technology, specifically to a method and system for the acceptance of medical device department rooms. Background Technology

[0002] The air cleanliness and surface cleanliness of critical areas such as operating rooms and clean rooms in hospitals are directly related to the quality of medical care, so environmental assessments of these critical areas are necessary.

[0003] In related technologies, methods such as sedimentation bacteria method are commonly used to achieve environmental assessment. However, the above methods rely on the sampling and cultivation of bacterial strains, making it difficult to achieve real-time assessment and resulting in poor assessment efficiency. Summary of the Invention

[0004] In view of the above problems, this disclosure provides a method and system for the acceptance of medical device department rooms.

[0005] According to a first aspect of this disclosure, a method for accepting medical device department rooms is provided, comprising: injecting a nuclear magnetic resonance (NMR) gas probe into a space to be evaluated using a gas probe injector to create an environmental disturbance between the NMR gas probe and the space to be evaluated, wherein the space to be evaluated includes a department room storing medical devices; and using a first NMR system arranged in the space to be evaluated to acquire NMR data of the space to be evaluated, obtaining NMR spectrum sequences of each spatial unit in the space to be evaluated, wherein the space to be evaluated is divided into multiple spatial units, and the NMR spectrum sequence of each spatial unit includes multiple NMR spectrum data ordered according to the acquisition time, the NMR spectrum data being used to characterize... The interaction between the nuclear magnetic resonance gas probe and the ambient gas in the space unit; using a second nuclear magnetic resonance system arranged in the space to be evaluated, nuclear magnetic resonance diffusion-weighted data acquisition is performed on the space to be evaluated to obtain diffusion-weighted imaging sequences of each space unit in the space to be evaluated. The diffusion-weighted imaging sequence of the space unit includes multiple diffusion-weighted images ordered according to the acquisition time. The diffusion-weighted imaging is used to characterize the gas diffusion state of the nuclear magnetic resonance gas probe in the space unit; and using a processor, based on the nuclear magnetic resonance spectrum sequence of each space unit in the space to be evaluated and the diffusion-weighted imaging sequence of each space unit in the space to be evaluated, the environmental state of the space to be evaluated is assessed to obtain the assessment results.

[0006] According to embodiments of this disclosure, spatial units are determined as follows: using a first or second nuclear magnetic resonance (NMR) system and employing three-dimensional spatial coding technology, the space to be evaluated is divided into multiple spatial units according to a preset resolution; using the first NMR system arranged within the space to be evaluated, NMR data is acquired to obtain the NMR spectrum sequence of each spatial unit in the space to be evaluated, including: running the first NMR system to excite the NMR gas probe to drive the NMR gas probe to interact with the ambient gas; continuously acquiring the interaction between gases in each spatial unit in the space to be evaluated for each spatial unit, obtaining NMR spectrum data at multiple acquisition times; and sorting the multiple NMR spectrum data according to the acquisition time to obtain the NMR spectrum sequence of the spatial unit.

[0007] According to embodiments of this disclosure, a second nuclear magnetic resonance (NMR) system arranged within the space to be evaluated is used to acquire NMR diffusion-weighted data of the space to be evaluated, obtaining a diffusion-weighted imaging sequence of each spatial unit in the space to be evaluated. This includes: configuring the control parameters of the second NMR system according to a first preset parameter value for each spatial unit, and using the second NMR system to excite NMR gas probes in the spatial unit to obtain first NMR signals at multiple acquisition times; configuring the control parameters of the second NMR system according to a second preset parameter value, and using the second NMR system to excite NMR gas probes in the spatial unit to obtain second NMR signals at multiple acquisition times; determining the gas diffusion state at each acquisition time based on the first and second NMR signals at each acquisition time; and sorting the multiple gas diffusion states according to the acquisition times to obtain a diffusion-weighted imaging sequence of the spatial units.

[0008] According to embodiments of this disclosure, an environmental state assessment of the space to be assessed is performed using a processor based on the nuclear magnetic resonance (NMR) spectrum sequences of each spatial unit in the space to be assessed and the diffusion-weighted imaging sequences of each spatial unit in the space to be assessed, to obtain an assessment result. This includes: determining the chemical shift sequence of the NMR gas probe based on the NMR spectrum sequences of each spatial unit, wherein the chemical shift sequence includes multiple chemical shifts ordered according to the acquisition time, and the chemical shift at each acquisition time is determined based on the shift between the NMR frequency shown in the NMR spectrum at the acquisition time and the reference NMR frequency of the NMR gas probe; and obtaining the assessment result based on the chemical shift sequence and the diffusion-weighted imaging sequence.

[0009] According to embodiments of this disclosure, the chemical shift sequence of a nuclear magnetic resonance gas probe is determined based on the nuclear magnetic resonance spectrum sequence of each space unit, including: for each acquisition time, determining the nuclear magnetic resonance frequency at the acquisition time according to the nuclear magnetic resonance spectrum sequence; determining the relative shift between the nuclear magnetic resonance frequency and the reference nuclear magnetic resonance frequency as the chemical shift; and sorting multiple chemical shifts according to the acquisition time to obtain a chemical shift sequence.

[0010] According to embodiments of this disclosure, an evaluation result is obtained based on a chemical shift sequence and a diffusion-weighted imaging sequence, including: for each spatial unit, determining the physical properties of the components in the spatial unit based on the chemical shift sequence; determining the geometric features of the components in the spatial unit based on the diffusion-weighted imaging sequence; determining a sub-evaluation result for the spatial unit based on the physical properties and geometric features; and obtaining an evaluation result based on the identification information of multiple spatial units, the mapping relationship between the identification information and the sequence, and the sub-evaluation results of multiple spatial units. The mapping relationship between the identification information and the sequence includes the mapping relationship between the identification information of multiple spatial units and multiple chemical shift sequences, and the mapping relationship between the identification information of multiple spatial units and multiple diffusion-weighted imaging sequences.

[0011] According to embodiments of this disclosure, determining the physical properties of the components in a space unit based on a chemical shift sequence includes: determining the shift of the nuclear magnetic resonance frequency characterized by the chemical shift of the nuclear magnetic resonance gas probe at each acquisition time, the shift including the nuclear magnetic resonance offset, the number of peaks, and the peak value; determining the chemical composition of the space unit based on the offset; determining the number of independent environments in the space unit based on the number of peaks; determining the capacity of each independent environment to accommodate the nuclear magnetic resonance gas probe based on the peak value of each peak; and determining the physical properties of the components in the space unit based on the chemical composition, the number of independent environments, and the capacity of each independent environment to accommodate the nuclear magnetic resonance gas probe.

[0012] According to embodiments of this disclosure, determining the geometric features of the components in a space cell based on a diffusion-weighted imaging sequence includes: determining the diffusion rate of a nuclear magnetic resonance gas probe within the space cell based on the diffusion-weighted imaging sequence; determining the tortuosity and connectivity of the space cell based on the standard diffusion rate and diffusion velocity of the nuclear magnetic resonance gas probe; and determining the geometric features based on the tortuosity and connectivity.

[0013] According to embodiments of this disclosure, injecting a nuclear magnetic resonance gas probe into a space to be evaluated to create an environmental disturbance between the nuclear magnetic resonance gas probe and the space to be evaluated includes: setting at least one injection point on the boundary of the space to be evaluated; and injecting the nuclear magnetic resonance gas probe into the space to be evaluated from the at least one injection point according to a preset injection method; when the boundary includes one injection point, the preset injection method includes at least one of the following: pulsed injection, steady-state injection; when the boundary includes multiple injection points, the preset injection method is multi-point synchronous injection.

[0014] A second aspect of this disclosure provides a medical device department room acceptance system, including a gas probe injector, a first nuclear magnetic resonance (NMR) system, a second NMR system, and a processor. The gas probe injector is configured to inject an NMR gas probe into a space to be evaluated, thereby creating an environmental disturbance between the NMR gas probe and the space to be evaluated, the space to be evaluated including a department room storing medical devices. The first NMR system is configured to acquire NMR data from the space to be evaluated, obtaining NMR spectrum sequences for each spatial unit within the space to be evaluated. The space to be evaluated is divided into multiple spatial units, and the NMR spectrum sequence for each spatial unit includes multiple NMR spectrum data ordered according to the acquisition time. The NMR spectrum data is used to characterize the interaction between the NMR gas probe and the ambient gas within the spatial unit. The second NMR system... The system is configured to acquire NMR diffusion-weighted data of the space to be evaluated, obtaining diffusion-weighted imaging sequences of each spatial unit in the space to be evaluated. The diffusion-weighted imaging sequence of the spatial unit includes multiple diffusion-weighted images ordered according to the acquisition time. The diffusion-weighted imaging is used to characterize the gas diffusion state of the NMR gas probe in the spatial unit. The processor is communicatively connected to the first NMR system and the second NMR system and is configured to receive the NMR spectrum sequences of each spatial unit in the space to be evaluated sent by the first NMR system and the diffusion-weighted imaging sequences of each spatial unit in the space to be evaluated sent by the second NMR system. Based on the NMR spectrum sequences and diffusion-weighted imaging sequences of each spatial unit in the space to be evaluated, the system performs an environmental state assessment of the space to be evaluated and obtains the assessment results.

[0015] A third aspect of this disclosure provides an electronic device comprising: one or more processors; and a memory for storing one or more computer programs, wherein the one or more processors execute the one or more computer programs to implement the steps of the method described above.

[0016] A fourth aspect of this disclosure also provides a computer-readable storage medium having a computer program or instructions stored thereon, which, when executed by a processor, implement the steps of the above-described method.

[0017] The fifth aspect of this disclosure also provides a computer program product, including a computer program or instructions that, when executed by a processor, implement the steps of the above-described method.

[0018] According to embodiments of this disclosure, environmental disturbances are created by actively injecting nuclear magnetic resonance (NMR) gas probes. Combined with a dual-NMR system, spectral sequences and diffusion-weighted imaging sequences of each space unit are acquired separately, enabling a multi-dimensional, high-precision joint assessment of the space environment state to be evaluated. Compared to traditional assessment methods without active disturbances and with single data acquisition, active probe injection amplifies differences in space environment characteristics. The dual-system acquisition captures gas interactions and diffusion states respectively, and the two work together to provide comprehensive data support for the assessment, effectively improving the accuracy, comprehensiveness, and real-time performance of environmental state assessments, and adapting to the refined assessment needs of complex spaces. Attached Figure Description

[0019] The foregoing contents, as well as other objects, features, and advantages of this disclosure, will become clearer from the following description of embodiments with reference to the accompanying drawings, in which:

[0020] Figure 1 This diagram schematically illustrates an application scenario of a medical device department room acceptance method and system according to embodiments of the present disclosure.

[0021] Figure 2 A flowchart illustrating a method for accepting medical device department rooms according to an embodiment of this disclosure is shown schematically.

[0022] Figure 3A This illustration schematically shows a method for determining chemical shift sequences in a medical device department room acceptance procedure according to an embodiment of the present disclosure;

[0023] Figure 3B The spectrum of a chemical shift sequence obtained by the medical device department room acceptance method according to an embodiment of the present disclosure is illustrated schematically.

[0024] Figure 4 This schematically illustrates the architecture of a medical device department room acceptance system according to an embodiment of the present disclosure; and

[0025] Figure 5 A block diagram schematically illustrates an electronic device suitable for implementing a medical device department room acceptance method according to an embodiment of the present disclosure. Detailed Implementation

[0026] The embodiments of the present disclosure will now be described with reference to the accompanying drawings. However, it should be understood that these descriptions are exemplary only and are not intended to limit the scope of the disclosure. In the following detailed description, numerous specific details are set forth to provide a thorough understanding of the embodiments of the present disclosure for ease of explanation. However, it will be apparent that one or more embodiments may be practiced without these specific details. Furthermore, descriptions of well-known structures and techniques are omitted in the following description to avoid unnecessarily obscuring the concepts of the present disclosure.

[0027] The terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit this disclosure. The terms “comprising,” “including,” etc., as used herein indicate the presence of the stated features, steps, operations, and / or components, but do not exclude the presence or addition of one or more other features, steps, operations, or components.

[0028] All terms used herein (including technical and scientific terms) have the meanings commonly understood by those skilled in the art, unless otherwise defined. It should be noted that the terms used herein are to be interpreted in a manner consistent with the context of this specification, and not in an idealized or overly rigid way.

[0029] When using expressions such as "at least one of A, B and C", they should generally be interpreted in accordance with the meaning that is commonly understood by those skilled in the art (e.g., "a system having at least one of A, B and C" should include, but is not limited to, a system having A alone, a system having B alone, a system having C alone, a system having A and B, a system having A and C, a system having B and C, and / or a system having A, B and C, etc.).

[0030] In the technical solution disclosed herein, the user information (including but not limited to user personal information, user image information, user device information, such as location information) and data (including but not limited to data used for analysis, stored data, and displayed data) involved are all information and data authorized by the user or fully authorized by all parties. Furthermore, the collection, storage, use, processing, transmission, provision, disclosure, and application of related data all comply with relevant laws, regulations, and standards, necessary confidentiality measures have been taken, and they do not violate public order and good morals. Corresponding operation entry points are provided for users to choose to authorize or refuse.

[0031] In scenarios involving automated decision-making using personal information, the methods, devices, and systems provided in this disclosure all offer users corresponding entry points for choosing to agree to or reject the automated decision-making results. If the user chooses to reject, the process proceeds to the expert decision-making stage. Here, "automated decision-making" refers to the activity of automatically analyzing and evaluating an individual's behavioral habits, interests, or economic, health, and credit status through computer programs, and then making a decision. Here, "expert decision-making" refers to the activity of making decisions by personnel who specialize in a particular field, possess specialized experience, knowledge, and skills, and have reached a certain level of professional expertise.

[0032] This disclosure provides a method for the acceptance of a medical device department room, comprising: injecting a nuclear magnetic resonance (NMR) gas probe into the space to be evaluated using a gas probe injector to create an environmental disturbance between the NMR gas probe and the space to be evaluated; and using a first NMR system arranged in the space to be evaluated to acquire NMR data of the space to be evaluated, obtaining the NMR spectrum sequence of each spatial unit in the space to be evaluated, wherein the space to be evaluated is divided into multiple spatial units, and the NMR spectrum sequence of each spatial unit includes multiple NMR spectrum data ordered according to the acquisition time, and the NMR spectrum data is used to characterize the NMR gas probe in the space. The interaction between the element and the ambient gas; using a second nuclear magnetic resonance system arranged in the space to be evaluated, nuclear magnetic resonance diffusion-weighted data acquisition is performed on the space to be evaluated to obtain diffusion-weighted imaging sequences of each spatial unit in the space to be evaluated. The diffusion-weighted imaging sequence of the spatial unit includes multiple diffusion-weighted images ordered according to the acquisition time. The diffusion-weighted imaging is used to characterize the gas diffusion state of the nuclear magnetic resonance gas probe in the spatial unit; and using a processor, based on the nuclear magnetic resonance spectrum sequence of each spatial unit in the space to be evaluated and the diffusion-weighted imaging sequence of each spatial unit in the space to be evaluated, the environmental state of the space to be evaluated is assessed to obtain the assessment results.

[0033] Figure 1 The illustration schematically depicts an application scenario of a medical device department room acceptance method, apparatus, equipment, medium, and procedure product according to embodiments of the present disclosure.

[0034] like Figure 1 As shown, the application scenario 100 according to this embodiment may include the space to be evaluated 110, the gas probe injector 120, and the nuclear magnetic resonance system 130.

[0035] The gas probe injector 120 is positioned at the boundary of the space to be evaluated 110 and is used to inject gas into the space to be evaluated 110, wherein the injected gas may be a nuclear magnetic resonance gas probe.

[0036] A nuclear magnetic resonance (NMR) system 130 is disposed inside the space 110 to be evaluated. It is used to excite the gas injected by the gas probe injector 120 via NMR and to collect NMR data after the gas is excited. The NMR system 130 may include a first NMR system 130_1 and a second NMR system 130_2. The number of NMR systems is exemplary; different numbers of NMR systems can be set depending on the volume and complexity of the space 110 to be evaluated.

[0037] The application scenario 100 may also include a processor for data processing, which can be electrically connected to the nuclear magnetic resonance system 130 to acquire and process the data collected by the nuclear magnetic resonance system 130, and determine the environmental conditions of the space 110 to be evaluated.

[0038] It should be noted that the medical device department room acceptance method provided in this disclosure embodiment can generally be executed by a processor. The medical device department room acceptance method provided in this disclosure embodiment can also be executed by a processor or processor cluster that is different from the processor and capable of communicating with the MRI system 130.

[0039] Figure 2 A flowchart illustrating a method for accepting medical device department rooms according to an embodiment of this disclosure is shown schematically.

[0040] like Figure 2 As shown, the medical device department room acceptance method of this embodiment includes operations S210 to S240.

[0041] In operation S210, a nuclear magnetic resonance gas probe is injected into the space to be evaluated using a gas probe injector to create an environmental disturbance between the nuclear magnetic resonance gas probe and the space to be evaluated.

[0042] In operation S220, the first nuclear magnetic resonance system arranged in the space to be evaluated is used to acquire nuclear magnetic resonance data of the space to be evaluated, and obtain the nuclear magnetic resonance spectrum sequence of each spatial unit in the space to be evaluated.

[0043] In operation S230, the second nuclear magnetic resonance system arranged in the space to be evaluated is used to acquire nuclear magnetic resonance diffusion-weighted data of the space to be evaluated, and the diffusion-weighted imaging sequence of each spatial unit in the space to be evaluated is obtained.

[0044] In operation S240, the processor uses the nuclear magnetic resonance spectrum sequence and diffusion-weighted imaging sequence of each spatial unit in the space to be evaluated to assess the environmental state of the space to be evaluated and obtain the assessment results.

[0045] The space to be evaluated can be a closed space that requires an environmental status assessment. In the embodiments of this disclosure, the space to be evaluated may include a department room where medical devices are stored. Specifically, the space to be evaluated may include spaces such as operating rooms and clean rooms in a hospital.

[0046] Gas probe injectors can be placed at the boundaries of the space to be evaluated, such as walls, floors, and ceilings. They are used to inject nuclear magnetic resonance (NMR) gas probes into the space. Furthermore, the flow rate, pressure, and timing of NMR gases can be controlled to adapt to different injection requirements.

[0047] The nuclear magnetic resonance gas probe can be a gas that responds to nuclear magnetic resonance; preferably, it can be a gas that responds to nuclear magnetic resonance. 129 Xe is used as a gas probe for nuclear magnetic resonance. 129 Xe is a chemically stable gaseous isotope. It possesses an atomic nucleus detectable by nuclear magnetic resonance (NMR), and its vast electron cloud is extremely sensitive to environmental disturbances, encoding the microscopic structural features of the probed space as significant NMR frequency shifts. Furthermore, its high diffusivity as a small-molecule gas allows it to penetrate complex spaces, and hyperpolarization techniques can amplify its NMR signal by tens of thousands of times.

[0048] 129 Xe possesses NMR-identifiable spectral characteristics and its inert nature prevents chemical reactions with the space environment, ensuring detection accuracy. Therefore, it can be used as a non-invasive, highly sensitive NMR gas probe for mapping the microstructure and gas transport function of space.

[0049] After injecting a nuclear magnetic resonance gas probe into the space to be evaluated, the nuclear magnetic resonance gas probe can interact with the gas in the environment of the space to be evaluated or the main structure of the space to be evaluated, forming an environmental disturbance between the nuclear magnetic resonance gas probe and the space to be evaluated.

[0050] A first nuclear magnetic resonance system can be set up in the space to be evaluated. The first nuclear magnetic resonance system can generate a main magnetic field, emit radio frequency pulses, and trigger resonance to excite the atomic nuclei of the nuclear magnetic resonance gas probe, so that the atomic nuclei of the nuclear magnetic resonance gas probe absorb energy and enter a high-energy state, and receive the nuclear magnetic resonance signal emitted by the atomic nuclei of the nuclear magnetic resonance gas probe in the high-energy state during the recovery process.

[0051] Nuclear magnetic resonance (NMR) data acquisition can refer to NMR spectral imaging acquisition. Specifically, the first NMR system can perform NMR spectral imaging acquisition after exciting the NMR gas probe to obtain the NMR spectrum sequence of each space unit in the space to be evaluated.

[0052] The space to be evaluated can be divided into multiple spatial units. The nuclear magnetic resonance spectrum sequence of each spatial unit includes multiple nuclear magnetic resonance spectrum data ordered according to the acquisition time. The nuclear magnetic resonance spectrum data is used to characterize the interaction between the nuclear magnetic resonance gas probe and the ambient gas in the spatial unit.

[0053] It should be noted that, since the space to be evaluated is divided into multiple spatial units, the first nuclear magnetic resonance system can acquire data for each spatial unit separately, obtaining the nuclear magnetic resonance spectrum sequence for each spatial unit. Therefore, spatial encoding can be performed on the basis of nuclear magnetic resonance spectral imaging acquisition, so that the acquired nuclear magnetic resonance spectrum sequence includes not only multiple nuclear magnetic resonance spectrum data ordered according to the acquisition time, but also the spatial encoding of the nuclear magnetic resonance spectrum sequence. The spatial encoding can be used to indicate the spatial unit corresponding to the nuclear magnetic resonance spectrum sequence.

[0054] A second nuclear magnetic resonance (NMR) system can also be installed in the space to be evaluated. The second NMR system operates on the same principle as the first NMR system. In particular, the second NMR system and the first NMR system can be the same NMR system or different NMR systems.

[0055] A second nuclear magnetic resonance (NMR) system can be used to excite an NMR gas probe and acquire NMR diffusion-weighted data of the space to be evaluated, resulting in diffusion-weighted imaging sequences for each space unit. The diffusion-weighted imaging sequence for each space unit includes multiple diffusion-weighted images ordered according to the acquisition time. These diffusion-weighted images are used to characterize the gas diffusion state of the NMR gas probe within the space unit.

[0056] It should be noted that the acquisition of NMR spectral sequences and diffusion-weighted imaging sequences can be performed simultaneously or sequentially. Acquiring these sequences sequentially allows for consistent distribution of the NMR gas probes in both processes, thus avoiding discrepancies in evaluation results caused by inconsistent NMR gas probe distributions.

[0057] Based on the nuclear magnetic resonance spectrum sequence and diffusion-weighted imaging sequence of each space unit, a multi-dimensional characterization of the space environment to be evaluated can be achieved, and the environmental status of each space unit can be evaluated. By summarizing the environmental status evaluation results of each space unit, the environmental status evaluation result of the space to be evaluated can be obtained.

[0058] According to embodiments of this disclosure, environmental disturbances are created by actively injecting nuclear magnetic resonance (NMR) gas probes. Combined with a dual-NMR system, spectral sequences and diffusion-weighted imaging sequences of each space unit are acquired separately, enabling a multi-dimensional, high-precision joint assessment of the space environment state to be evaluated. Compared to traditional assessment methods without active disturbances and with single data acquisition, active probe injection amplifies differences in space environment characteristics. The dual-system acquisition captures gas interactions and diffusion states respectively, and the two work together to provide comprehensive data support for the assessment, effectively improving the accuracy, comprehensiveness, and real-time performance of environmental state assessments, and adapting to the refined assessment needs of complex spaces.

[0059] According to embodiments of this disclosure, spatial units are determined as follows: using a first or second nuclear magnetic resonance system, and employing three-dimensional spatial coding technology, the space to be evaluated is divided into multiple spatial units according to a preset resolution. The three-dimensional spatial coding technology may include phase coding, frequency coding, layer selection coding, etc.

[0060] The preset resolution can be set according to the actual application needs. When the evaluation accuracy is high, the preset resolution can be set to the millimeter level. Therefore, the spatial positioning accuracy of the spatial unit obtained after three-dimensional spatial coding is higher, and it can identify more subtle differences in the local physical environment. It is suitable for evaluating enclosed spaces with complex structures that require fine analysis.

[0061] When the accuracy requirement is not high, the preset resolution can be set to decimeter level, centimeter level, etc., so the signal acquisition efficiency is higher and the signal-to-noise ratio is better, which is suitable for evaluating large-volume, simple-structure enclosed spaces.

[0062] Using three-dimensional spatial coding technology, the space to be evaluated is divided into multiple independent, non-overlapping cubes with three-dimensional dimensions and clear spatial locations and volumes, which serve as spatial units. The spatial unit is the smallest unit for nuclear magnetic resonance signal acquisition in this embodiment of the present disclosure.

[0063] Using a first or second nuclear magnetic resonance (NMR) system and three-dimensional spatial coding technology, the space to be evaluated can be divided according to a preset resolution to obtain multiple spatial units and their corresponding three-dimensional spatial codes. These three-dimensional spatial codes can be used to uniquely identify each spatial unit.

[0064] By dividing the space into three dimensions, the overall evaluation of the space to be evaluated can be transformed into the evaluation of multiple spatial units. This not only achieves finer granularity but also enables a detailed evaluation of the space to be evaluated, identifying the differences between multiple spatial units.

[0065] Using a first nuclear magnetic resonance (NMR) system deployed within the space to be evaluated, NMR data is acquired to obtain the NMR spectrum sequence of each spatial unit in the space to be evaluated. This includes: running the first NMR system and exciting the NMR gas probe to drive the interaction between the NMR gas probe and the ambient gas; continuously acquiring the interaction between gases in each spatial unit in the space to be evaluated for each spatial unit, obtaining NMR spectrum data at multiple acquisition times; and sorting the multiple NMR spectrum data according to the acquisition time to obtain the NMR spectrum sequence of the spatial unit.

[0066] After the first nuclear magnetic resonance system is put into operation, it excites the nuclear magnetic resonance gas probe by generating a magnetic field, emitting radio frequency pulses, and triggering resonance, thereby driving the nuclear magnetic resonance gas probe to interact with the ambient gas.

[0067] In each spatial cell, the interactions between gases within that cell are acquired at multiple acquisition times, resulting in NMR spectrum data for the NMR gas probe at each acquisition time. These NMR data are then sorted according to their acquisition times to obtain the NMR spectrum sequence for that spatial cell. The NMR spectrum data may include characteristic parameters such as the peak value, peak shape, and peak width of the NMR gas probe's resonance peaks, as well as peak shifts caused by the influence of other gases.

[0068] Specifically, after exciting the nuclear magnetic resonance gas probe in the space unit using the first nuclear magnetic resonance system, the nuclear magnetic resonance free induction decay signal of the space unit can be collected, and the above signal can be Fourier transformed into nuclear magnetic resonance spectrum data including the peak value, peak shape, peak width, and shift of the resonance peak.

[0069] According to embodiments of this disclosure, three-dimensional spatial coding technology is used to divide spatial units at a preset resolution, achieving refined zoning and control of the space to be evaluated. Simultaneously, the acquisition logic of the spectral sequence is clearly defined, ensuring accurate traceability of gas interaction data for each spatial unit. Three-dimensional coding solves the evaluation bias problem caused by the coarseness of traditional zoning. It continuously acquires and sorts spectral data according to the acquisition time, fully capturing the dynamic changes in the interaction between the probe and environmental gases. This provides continuous and reliable basic data for subsequent chemical shift analysis and environmental feature extraction, further improving the refinement of the evaluation.

[0070] According to embodiments of this disclosure, a second nuclear magnetic resonance (NMR) system arranged within the space to be evaluated is used to acquire NMR diffusion-weighted data of the space to be evaluated, obtaining a diffusion-weighted imaging sequence of each spatial unit in the space to be evaluated. This includes: configuring the control parameters of the second NMR system according to a first preset parameter value for each spatial unit, and using the second NMR system to excite NMR gas probes in the spatial unit to obtain first NMR signals at multiple acquisition times; configuring the control parameters of the second NMR system according to a second preset parameter value, and using the second NMR system to excite NMR gas probes in the spatial unit to obtain second NMR signals at multiple acquisition times; determining the gas diffusion state at each acquisition time based on the first and second NMR signals at each acquisition time; and sorting the multiple gas diffusion states according to the acquisition times to obtain a diffusion-weighted imaging sequence of the spatial units.

[0071] The second control parameter of the nuclear magnetic resonance system refers to the b-value, a core parameter of nuclear magnetic diffusion-weighted imaging. The b-value is a physical quantity determined by the gradient field parameter and used to control the sensitivity of the experiment to the detection of molecular diffusion. The larger the b-value, the higher the sensitivity to the monitoring of molecular diffusion.

[0072] In the embodiments of this disclosure, the first preset parameter value can be greater than the second preset parameter value. The control parameters are configured using the first and second preset parameter values ​​respectively, and the configured model is used to excite the nuclear magnetic resonance gas probe in the space unit to acquire the first and second nuclear magnetic resonance signals at multiple acquisition times.

[0073] For example, the first preset parameter value can be set to 50s / mm. 2 The second preset parameter value is set to 0. The second NMR system configured using the first preset parameter value is more sensitive to diffusion. During diffusion, the NMR signal of the NMR gas probe undergoes characteristic attenuation due to the gradient magnetic field; the more intense the diffusion process, the more pronounced the signal attenuation. The second NMR system configured using the second preset parameter is less sensitive to diffusion, and the acquired signal is primarily composed of the NMR background signal of the NMR gas probe, reflecting the spatial distribution concentration of the probe and providing a reference for the diffusion signal.

[0074] Furthermore, in the second NMR system, all parameters except the control parameters can be fixed, and only preset parameter values ​​can be adjusted to ensure that the difference between the first and second NMR signals is caused solely by the difference in control parameters. Additionally, the same signal acquisition location can be selected for acquisition to further eliminate differences caused by other factors.

[0075] Specifically, other parameters may include NMR parameters. For example, radio frequency pulse intensity or duration, spatial coding method, voxel segmentation resolution, signal acquisition duration, etc.

[0076] Based on the first and second NMR signals, the diffusion of the NMR gas probe under different control parameters at the same acquisition time can be determined. From the above special cases, the diffusion of the NMR gas probe under normal circumstances can be deduced as the gas diffusion state at that acquisition time.

[0077] It is understood that the above embodiments are merely exemplary. Depending on the different accuracy requirements in actual applications, multiple preset parameter values ​​can be set and multiple excitations can be performed to obtain multiple NMR signals at each acquisition moment and determine the gas diffusion state.

[0078] By sorting multiple gas diffusion states of the same spatial cell according to the acquisition time, the diffusion-weighted imaging sequence of that spatial cell can be obtained.

[0079] According to embodiments of this disclosure, a second nuclear magnetic resonance (NMR) system is controlled by dual preset parameter configuration to acquire NMR signals under different parameters and deduce the diffusion state of the NMR gas probe, thereby achieving accurate generation of diffusion-weighted imaging sequences. The dual-parameter configuration can specifically capture gas states with different diffusion characteristics, avoiding the omission of diffusion information caused by single-parameter acquisition. The imaging sequence, with signals superimposed from multiple acquisition moments, can fully reflect the dynamic law of probe diffusion, improve the accuracy of diffusion state characterization, and provide high-quality data support for subsequent geometric feature evaluation.

[0080] According to embodiments of this disclosure, an environmental state assessment of the space to be assessed is performed using a processor based on the nuclear magnetic resonance (NMR) spectrum sequences of each spatial unit in the space to be assessed and the diffusion-weighted imaging sequences of each spatial unit in the space to be assessed, to obtain an assessment result. This includes: determining the chemical shift sequence of the NMR gas probe based on the NMR spectrum sequences of each spatial unit, wherein the chemical shift sequence includes multiple chemical shifts ordered according to the acquisition time, and the chemical shift at each acquisition time is determined based on the shift between the NMR frequency shown in the NMR spectrum at the acquisition time and the reference NMR frequency of the NMR gas probe; and obtaining the assessment result based on the chemical shift sequence and the diffusion-weighted imaging sequence.

[0081] The processor can acquire nuclear magnetic resonance spectrum sequences and diffusion-weighted imaging sequences from the first and second nuclear magnetic resonance systems, respectively, and process the sequences to complete the environmental state assessment of the space to be evaluated.

[0082] Chemical shift refers to the minute deviation of the resonance frequency of an atomic nucleus relative to a certain standard reference. The core of it is the characteristic change in the resonance frequency caused by different chemical or physical environments around the atomic nucleus.

[0083] Specifically, the resonance frequency of an atomic nucleus is proportional to the effective magnetic field. When the effective magnetic field changes, the resonance frequency will change accordingly, resulting in a shift in the resonance frequency after the change compared to the resonance frequency before the change in the magnetic field. This shift is called chemical shift.

[0084] For the same nuclear magnetic resonance gas probe, the amount of chemical shift will vary depending on the environment or the degree of excitation it receives. Therefore, the environment of the space unit where the nuclear magnetic resonance gas probe is located can be inferred from the chemical shift.

[0085] Specifically, determining the chemical shift sequence of the nuclear magnetic resonance gas probe based on the nuclear magnetic resonance spectrum sequence of each space unit may include: determining the nuclear magnetic resonance frequency at each acquisition time according to the nuclear magnetic resonance spectrum sequence; determining the relative shift between the nuclear magnetic resonance frequency and the reference nuclear magnetic resonance frequency as the chemical shift; and sorting multiple chemical shifts according to the acquisition time to obtain the chemical shift sequence.

[0086] The NMR spectral sequence comprises NMR frequencies at multiple acquisition times. Based on the NMR frequency at each acquisition time and the reference NMR frequency of the NMR gas probe in its unexcited state, the chemical shifts resulting from the excitation operation can be determined. By sorting the multiple chemical shifts according to the acquisition times, a chemical shift sequence can be obtained.

[0087] Furthermore, the environmental state of the space to be evaluated can be assessed based on the chemical shift sequence and diffusion-weighted imaging sequence to obtain the evaluation results.

[0088] According to embodiments of this disclosure, chemical shift sequences are extracted based on spectral sequences and combined with diffusion-weighted imaging sequences to achieve a two-dimensional assessment of chemical properties and diffusion states, enriching the assessment dimensions and enhancing the assessment depth. Chemical shifts are determined by the relative shift between the nuclear magnetic resonance frequency and the reference frequency at the acquisition time, enabling standardized and precise calculation of chemical shifts. This provides accurate quantitative evidence for subsequent physical property analysis, further improving the standardization of the assessment process and the accuracy of the assessment results. Chemical shift sequences can accurately characterize the interaction between the probe and the ambient gas, reflecting spatial compositional differences. Combined with diffusion state data from diffusion-weighted imaging sequences, this overcomes the limitations of single-dimensional assessment, achieving a comprehensive analysis of the space environment state and improving the scientific rigor and reliability of the assessment results.

[0089] According to embodiments of this disclosure, an evaluation result is obtained based on a chemical shift sequence and a diffusion-weighted imaging sequence, including: for each spatial unit, determining the physical properties of the components in the spatial unit based on the chemical shift sequence; determining the geometric features of the components in the spatial unit based on the diffusion-weighted imaging sequence; determining a sub-evaluation result for the spatial unit based on the physical properties and geometric features; and obtaining an evaluation result based on the identification information of multiple spatial units, the mapping relationship between the identification information and the sequence, and the sub-evaluation results of multiple spatial units. The mapping relationship between the identification information and the sequence includes the mapping relationship between the identification information of multiple spatial units and multiple chemical shift sequences, and the mapping relationship between the identification information of multiple spatial units and multiple diffusion-weighted imaging sequences.

[0090] Chemical shift is sensitive to the physical environment. Therefore, based on the chemical shift at each acquisition time, the physical properties of the components of multiple spatial units in the space to be evaluated, as well as the differences in physical properties between the components of multiple spatial units, can be determined by the differences in spectral characteristics.

[0091] The components may include other gaseous components in the space unit besides the nuclear magnetic resonance gas probe, as well as structural components such as beams and walls within the space unit. Physical properties may include temperature, pressure, gaseous medium composition, and structural component characteristics.

[0092] Diffusion-weighted imaging can determine the signal attenuation law and diffusion coefficient of nuclear magnetic resonance gas probes under different control parameters. Therefore, based on diffusion-weighted imaging sequences, the apparent diffusion coefficient, diffusion direction, and diffusion restriction degree of nuclear magnetic resonance gas probes in space units can be determined. Then, based on the above parameters, the geometric characteristics such as pore structure, spatial connectivity, and gas flow resistance in space units can be determined.

[0093] By associating the physical properties and geometric features of each spatial unit, the sub-evaluation results for each spatial unit can be determined. Based on the identification information of multiple spatial units, the mapping relationship between the identification information and the aforementioned chemical shift sequence and diffusion-weighted imaging sequence, and the sub-evaluation results of multiple spatial units, each spatial unit of the space to be evaluated can be associated with the sub-evaluation results at that location, thereby determining the evaluation result of the space to be evaluated.

[0094] According to embodiments of this disclosure, chemical shift can be used to obtain the resonance frequency shift of atomic nuclei in a nuclear magnetic resonance (NMR) gas probe, reflecting the static physical environment characteristics of the local space. Diffusion-weighted imaging can be used to obtain the molecular diffusion behavior of the NMR gas probe, reflecting dynamic characteristics such as spatial connectivity and pore structure. Combining these two methods enables a comprehensive and accurate assessment of the space to be evaluated.

[0095] According to embodiments of this disclosure, determining the physical properties of the components in a space unit based on a chemical shift sequence includes: determining the shift of the nuclear magnetic resonance frequency characterized by the chemical shift of the nuclear magnetic resonance gas probe at each acquisition time, the shift including the nuclear magnetic resonance offset, the number of peaks, and the peak value; determining the chemical composition of the space unit based on the offset; determining the number of independent environments in the space unit based on the number of peaks; determining the capacity of each independent environment to accommodate the nuclear magnetic resonance gas probe based on the peak value of each peak; and determining the physical properties of the components in the space unit based on the chemical composition, the number of independent environments, and the capacity of each independent environment to accommodate the nuclear magnetic resonance gas probe.

[0096] Typically, nuclides that are extremely sensitive to their physical environment can be selected as nuclear magnetic resonance (NMR) gas probes. Therefore, when parameters such as local pressure and temperature change within a space cell, corresponding chemical shifts will occur. Similarly, when the NMR gas probe comes into contact with different media within a space cell, corresponding chemical shifts will also occur. Thus, when multiple sub-regions with different physical properties exist within the same space cell, multiple chemical shifts can occur.

[0097] Different chemical shifts present different peaks on the spectrum. Therefore, the number of peaks can be counted. If there are multiple peaks indicating the presence of chemical shifts, it can be determined that there are multiple sub-regions with different physical properties in the spatial unit.

[0098] The number of independent environments in a spatial unit can be determined based on the number of peaks, where each independent environment corresponds to a sub-region with different physical properties.

[0099] Furthermore, the capacity of an independent environment to accommodate a nuclear magnetic resonance gas probe can be determined based on the peak value corresponding to each independent environment.

[0100] Different shifts in chemical shift indicate different causes for the shift. Therefore, the pressure, temperature, and medium within the space cell, i.e., the chemical composition of the space cell, can be determined based on the shift. It can be understood that in the presence of multiple peaks, the shift represents the chemical composition of the space cell corresponding to that peak.

[0101] Figure 3A The diagram illustrates a method for determining chemical shift sequences in a medical device department room acceptance procedure according to an embodiment of the present disclosure.

[0102] like Figure 3A As shown, the horizontal axis of the spectrum represents time t, and the vertical axis represents frequency f. Figure 3AThe dashed line represents the curve of the reference nuclear magnetic resonance frequency changing over time, while the solid line represents the curve of the nuclear magnetic resonance frequency changing over time.

[0103] Based on the two curves mentioned above, the chemical shift at each acquisition moment can be obtained by subtracting the reference NMR frequency from the NMR frequency.

[0104] For example, for acquisition time t1, with reference NMR frequency f1' and NMR frequency f1, the chemical shift at acquisition time t1 is the difference between the two, i.e., f1' - f1. Similarly, the chemical shift at acquisition time t2 is f2' - f2, and the chemical shift at acquisition time t3 is f3' - f3.

[0105] Figure 3B The spectrum of the chemical shift sequence obtained by the medical device department room acceptance method according to an embodiment of the present disclosure is illustrated schematically.

[0106] like Figure 3B As shown, the horizontal axis of the spectrum represents time t, and the vertical axis represents chemical shift δ.

[0107] Figure 3B The ordinate value at each acquisition time is obtained through... Figure 3A The values ​​are obtained from the calculation process. For example, the ordinate of acquisition time t1 is δ1 = f1' - f1, the ordinate of acquisition time t2 is δ2 = f2' - f2, and the ordinate of acquisition time t3 is δ3 = f3' - f3.

[0108] Analysis of the spectrum reveals that it contains three peaks. The acquisition times of the three peaks from left to right are t1, t2, and t3, and their corresponding chemical shifts are δ1, δ2, and δ3, respectively.

[0109] Therefore, it can be determined that there are three independent environments in this space unit, and the chemical composition of each independent environment and its capacity to accommodate nuclear magnetic resonance gas probes can be obtained by analyzing δ1, δ2 and δ3 respectively.

[0110] Based on the chemical composition obtained from the analysis, the number of independent environments, and the capacity of each independent environment to accommodate the nuclear magnetic resonance gas probe, the physical properties of the components in the space unit can be comprehensively determined.

[0111] According to embodiments of this disclosure, the chemical composition, number of independent environments, and carrying capacity of a space unit are analyzed based on three dimensions: the offset, number of peaks, and peak value of the chemical shift sequence, respectively, achieving a refined and multi-dimensional characterization of physical properties. Compared to traditional methods of characterizing physical properties using a single indicator, multi-dimensional indicators can comprehensively capture the intrinsic environmental characteristics of the space unit, avoiding the one-sidedness of physical property assessment, making the determination of physical properties more consistent with the actual environment, and providing more accurate feature support for the overall assessment.

[0112] According to embodiments of this disclosure, determining the geometric features of the components in a space cell based on a diffusion-weighted imaging sequence includes: determining the diffusion rate of a nuclear magnetic resonance gas probe within the space cell based on the diffusion-weighted imaging sequence; determining the tortuosity and connectivity of the space cell based on the standard diffusion rate and diffusion velocity of the nuclear magnetic resonance gas probe; and determining the geometric features based on the tortuosity and connectivity.

[0113] In this embodiment of the disclosure, the signal attenuation law under different control parameter values ​​can be determined by diffusion-weighted imaging sequence, so as to realize the quantitative calculation and qualitative analysis of the apparent diffusion behavior of nuclear magnetic resonance gas probe. The apparent diffusion coefficient is the core quantitative indicator characterizing diffusion behavior, so the analysis can be carried out around the apparent diffusion coefficient.

[0114] Specifically, the exponential decay relationship of the NMR signal intensity under different control parameter values ​​can be determined by equation (1):

[0115] (1)

[0116] Where S(b) represents the NMR signal intensity of the NMR gas probe when the control parameter is b, S0 represents the NMR signal intensity of the NMR gas probe when the control parameter is 0, b is the diffusion weighting factor, ADC is the apparent diffusion coefficient, which is used to characterize the diffusion capability of the NMR gas probe, that is, the diffusion rate of the NMR gas probe in the space unit, and e is the natural base.

[0117] The apparent diffusion coefficient of each spatial unit can be calculated using equation (1). By comparing the apparent diffusion coefficients of different spatial units, the differences between the apparent diffusion coefficients of different spatial units and the signal attenuation trend of different spatial units can be determined.

[0118] For a given spatial cell, a larger ADC value indicates a more vigorous diffusion motion of the NMR gas probe within that spatial cell and a smaller spatial constraint. Conversely, a smaller ADC value indicates a slower diffusion motion of the NMR gas probe within that spatial cell and a greater spatial constraint.

[0119] The first and second preset parameter values ​​can be substituted into equation (1) to obtain the standard diffusion rate and diffusion rate of the nuclear magnetic resonance gas probe, respectively. For example, when the first preset parameter value is 50 and the second preset parameter value is 0, 50 and 0 are substituted into equation (1) to solve for the ADC value in S(50) as the diffusion rate of the nuclear magnetic resonance gas probe in the space unit, and the ADC value in S(0) as the standard diffusion rate of the nuclear magnetic resonance gas probe in the space unit.

[0120] When using two preset parameter values ​​b1 and b0 as control parameters, the ADC value can be calculated using equation (2):

[0121] (2)

[0122] By comparing the diffusion rate with the standard diffusion rate, the degree of diffusion restriction of a spatial cell can be determined. For example, by comparing the signal attenuation rates represented by the ADC values ​​of the two, a higher attenuation rate indicates less restriction of diffusion by space or medium, while a lower attenuation rate indicates greater restriction of diffusion by space or medium. Based on the degree of restriction, aspects of the spatial cell's tortuosity, such as enclosed voids and high-resistance walls, can be predicted and evaluated.

[0123] By applying gradient magnetic fields in different directions to a space cell, the directional differences in different ADC values ​​can be determined. If the ADC value in one direction is significantly higher than in other directions, it indicates that the diffusion of the nuclear magnetic resonance gas probe along that direction is smoother, and the connectivity of the space cell can be predicted and evaluated.

[0124] For example, if it is determined that the diffusion of the nuclear magnetic resonance gas probe is smoother in the east-west direction, it can be determined that there is an east-west connecting channel in the space unit.

[0125] Once the degree of tortuosity and connectivity are determined, the overall geometric characteristics of the spatial unit can be determined by comprehensively considering both factors.

[0126] According to embodiments of this disclosure, the probe diffusion rate is determined using diffusion-weighted imaging sequences, and the tortuosity and connectivity of space units are deduced by combining standard diffusion rates, thus achieving a quantitative assessment of geometric features. The diffusion rate is directly related to the spatial geometry, and this derivation logic can transform diffusion state data into intuitive geometric feature parameters, solving the problem of the difficulty in quantifying traditional geometric features, improving the accuracy of geometric feature assessment, and providing a reliable basis for structural analysis of the space environment.

[0127] According to embodiments of this disclosure, injecting a nuclear magnetic resonance gas probe into a space to be evaluated to create an environmental disturbance between the nuclear magnetic resonance gas probe and the space to be evaluated includes: setting at least one injection point on the boundary of the space to be evaluated; and injecting the nuclear magnetic resonance gas probe into the space to be evaluated from the at least one injection point according to a preset injection method; when the boundary includes one injection point, the preset injection method includes at least one of the following: pulsed injection, steady-state injection; when the boundary includes multiple injection points, the preset injection method is multi-point synchronous injection.

[0128] The boundary of the space to be evaluated may include walls, ceilings, floors, etc. The injection point can be a gas orifice. A gas orifice for injecting the nuclear magnetic resonance gas probe is set at the aforementioned boundary location as the injection point.

[0129] The preset injection method can be determined based on the number of injection points, and the nuclear magnetic resonance gas probe can be injected into the space to be evaluated from the injection points according to the preset injection method.

[0130] In cases where there is only one injection point at the boundary, the preset injection method can be either pulse injection or steady-state injection.

[0131] Pulsed injection refers to the intermittent release of NMR gas probes into the space to be evaluated. Pulsed injection is suitable for evaluating the transient diffusion characteristics of gases in the space to be evaluated and the corresponding behavior of the NMR gas probes in response to the environment of the space to be evaluated.

[0132] Steady-state injection refers to the continuous and uniform release of NMR gas probes into the space to be evaluated until the concentration of the NMR gas probes in the space reaches dynamic equilibrium. Steady-state injection is suitable for evaluating the steady-state gas distribution characteristics and environmental homogeneity of the space to be evaluated.

[0133] When there are multiple injection points at the boundary, the default injection method can be multi-point synchronous injection.

[0134] Multi-point synchronous injection refers to the simultaneous release of NMR gas probes into the space to be evaluated from multiple injection points. Multi-point synchronous injection is suitable for achieving full-domain gas perturbation and distribution coverage of the space to be evaluated in large volumes and complex structures, and can avoid the signal blind zone of single-point injection.

[0135] According to embodiments of this disclosure, the preset injection method is optimized based on the number of injection points. Single injection points employ pulsed or steady-state injection, while multiple injection points use synchronous injection to ensure uniform distribution of the nuclear magnetic resonance gas probe within the space to be evaluated. This rational injection method design avoids data acquisition deviations caused by uneven probe distribution. Flexible injection at a single point can adapt to different space scales, while synchronous injection at multiple points improves injection efficiency and uniformity, laying the foundation for the accuracy of subsequent dual-system data acquisition and further ensuring the reliability of the evaluation results.

[0136] Based on the above-mentioned medical device department room acceptance method, this disclosure also provides a medical device department room acceptance system. The following will be combined with... Figure 4 The system is described in detail.

[0137] Figure 4 The diagram illustrates the architecture of a medical device department room acceptance system according to an embodiment of the present disclosure.

[0138] like Figure 4 As shown, the medical device department room acceptance system 400 of this embodiment includes a probe injector 410, a first MRI system 420, a second MRI system 430, and a processor 440. The processor 440 is communicatively connected to the first MRI system 420 and the second MRI system 430.

[0139] The gas probe injector 410 is configured to inject a nuclear magnetic resonance gas probe into a space to be evaluated, thereby creating an environmental disturbance between the nuclear magnetic resonance gas probe and the space to be evaluated, including a department room where medical devices are stored.

[0140] The first nuclear magnetic resonance system 420 is configured to acquire nuclear magnetic resonance data of the space to be evaluated, and obtain the nuclear magnetic resonance spectrum sequence of each spatial unit in the space to be evaluated. The space to be evaluated is divided into multiple spatial units, and the nuclear magnetic resonance spectrum sequence of the spatial unit includes multiple nuclear magnetic resonance spectrum data ordered according to the acquisition time. The nuclear magnetic resonance spectrum data is used to characterize the interaction between the nuclear magnetic resonance gas probe and the ambient gas in the spatial unit.

[0141] The second nuclear magnetic resonance system 430 is configured to acquire nuclear magnetic resonance diffusion-weighted data of the space to be evaluated, and obtain diffusion-weighted imaging sequences of each space cell in the space to be evaluated. The diffusion-weighted imaging sequence of the space cell includes multiple diffusion-weighted images ordered according to the acquisition time. The diffusion-weighted imaging is used to characterize the gas diffusion state of the nuclear magnetic resonance gas probe in the space cell.

[0142] The processor 440 is configured to receive the nuclear magnetic resonance spectrum sequence of each spatial unit in the space to be evaluated transmitted by the first nuclear magnetic resonance system, and the diffusion-weighted imaging sequence of each spatial unit in the space to be evaluated transmitted by the second nuclear magnetic resonance system, and to perform an environmental state assessment of the space to be evaluated based on the nuclear magnetic resonance spectrum sequence and the diffusion-weighted imaging sequence of each spatial unit in the space to be evaluated, thereby obtaining the assessment result.

[0143] Figure 5 A block diagram schematically illustrates an electronic device suitable for implementing a medical device department room acceptance method according to an embodiment of the present disclosure.

[0144] like Figure 5 As shown, an electronic device 500 according to an embodiment of the present disclosure includes a processor 501, which can perform various appropriate actions and processes according to a program stored in a read-only memory (ROM) 502 or a program loaded from a storage portion 508 into a random access memory (RAM) 503. The processor 501 may include, for example, a general-purpose microprocessor (e.g., a CPU), an instruction set processor and / or an associated chipset and / or a special-purpose microprocessor (e.g., an application-specific integrated circuit (ASIC)), etc. The processor 501 may also include onboard memory for caching purposes. The processor 501 may include a single processing unit or multiple processing units for performing different actions of the method flow according to an embodiment of the present disclosure.

[0145] RAM 503 stores various programs and data required for the operation of electronic device 500. Processor 501, ROM 502, and RAM 503 are interconnected via bus 504. Processor 501 performs various operations of the method flow according to embodiments of the present disclosure by executing programs in ROM 502 and / or RAM 503. It should be noted that the programs may also be stored in one or more memories other than ROM 502 and RAM 503. Processor 501 may also perform various operations of the method flow according to embodiments of the present disclosure by executing programs stored in said one or more memories.

[0146] According to embodiments of this disclosure, the electronic device 500 may further include an input / output (I / O) interface 505, which is also connected to a bus 504. The electronic device 500 may also include one or more of the following components connected to the input / output (I / O) interface 505: an input section 506 including a keyboard, mouse, etc.; an output section 507 including a cathode ray tube (CRT), liquid crystal display (LCD), etc., and a speaker, etc.; a storage section 508 including a hard disk, etc.; and a communication section 509 including a network interface card such as a LAN card, modem, etc. The communication section 509 performs communication processing via a network such as the Internet. A drive 510 is also connected to the input / output (I / O) interface 505 as needed. A removable medium 511, such as a disk, optical disk, magneto-optical disk, semiconductor memory, etc., is installed on the drive 510 as needed so that computer programs read from it can be installed into the storage section 508 as needed.

[0147] This disclosure also provides a computer-readable storage medium, which may be included in the device / apparatus / system described in the above embodiments; or it may exist independently and not assembled into the device / apparatus / system. The computer-readable storage medium carries one or more programs that, when executed, implement the method according to the embodiments of this disclosure.

[0148] According to embodiments of this disclosure, the computer-readable storage medium may be a non-volatile computer-readable storage medium, such as including, but not limited to: portable computer disks, hard disks, random access memory (RAM), read-only memory (ROM), erasable programmable read-only memory (EPROM or flash memory), portable compact disk read-only memory (CD-ROM), optical storage devices, magnetic storage devices, or any suitable combination thereof. In this disclosure, the computer-readable storage medium may be any tangible medium that contains or stores a program that can be used by or in conjunction with an instruction execution system, apparatus, or device. For example, according to embodiments of this disclosure, the computer-readable storage medium may include ROM 502 and / or RAM 503 and / or one or more memories other than ROM 502 and RAM 503 described above.

[0149] Embodiments of this disclosure also include a computer program product comprising a computer program containing program code for performing the methods shown in the flowchart. When the computer program product is run on a computer system, the program code is used to cause the computer system to implement the methods provided in the embodiments of this disclosure.

[0150] When the computer program is executed by the processor 501, it performs the functions defined in the system / apparatus of this disclosure embodiments. According to embodiments of this disclosure, the systems, apparatuses, modules, units, etc., described above can be implemented by computer program modules.

[0151] In one embodiment, the computer program may rely on a tangible storage medium such as an optical storage device or a magnetic storage device. In another embodiment, the computer program may also be transmitted and distributed in the form of signals over a network medium, and may be downloaded and installed via the communication section 509, and / or installed from a removable medium 511. The program code contained in the computer program can be transmitted using any suitable network medium, including but not limited to: wireless, wired, etc., or any suitable combination thereof.

[0152] In such an embodiment, the computer program can be downloaded and installed from a network via communication section 509, and / or installed from removable medium 511. When the computer program is executed by processor 501, it performs the functions defined in the system of this disclosure embodiment. According to embodiments of this disclosure, the systems, devices, apparatuses, modules, units, etc., described above can be implemented by computer program modules.

[0153] According to embodiments of this disclosure, program code for executing the computer programs provided in embodiments of this disclosure can be written in any combination of one or more programming languages. Specifically, these computational programs can be implemented using high-level procedural and / or object-oriented programming languages, and / or assembly / machine languages. Programming languages ​​include, but are not limited to, languages ​​such as Java, C++, Python, "C", or similar programming languages. The program code can execute entirely on a user's computing device, partially on a user's device, partially on a remote computing device, or entirely on a remote computing device or server. In cases involving remote computing devices, the remote computing device can be connected to the user's computing device via any type of network, including a local area network (LAN) or a wide area network (WAN), or it can be connected to an external computing device (e.g., via the Internet using an Internet service provider).

[0154] The flowcharts and block diagrams in the accompanying drawings illustrate the architecture, functionality, and operation of possible implementations of systems, methods, and computer program products according to various embodiments of this disclosure. In this regard, each block in a flowchart or block diagram may represent a module, segment, or portion of code containing one or more executable instructions for implementing a specified logical function. It should also be noted that in some alternative implementations, the functions indicated in the blocks may occur in a different order than those indicated in the drawings. For example, two consecutively indicated blocks may actually be executed substantially in parallel, and they may sometimes be executed in reverse order, depending on the functions involved. It should also be noted that each block in a block diagram or flowchart, and combinations of blocks in a block diagram or flowchart, may be implemented using a dedicated hardware-based system that performs the specified function or operation, or using a combination of dedicated hardware and computer instructions.

[0155] Those skilled in the art will understand that the features described in the various embodiments of this disclosure can be combined and / or combined in various ways, even if such combinations or combinations are not explicitly described in this disclosure. In particular, the features described in the various embodiments of this disclosure can be combined and / or combined in various ways without departing from the spirit and teachings of this disclosure. All such combinations and / or combinations fall within the scope of this disclosure.

[0156] The embodiments of this disclosure have been described above. However, these embodiments are for illustrative purposes only and are not intended to limit the scope of this disclosure. Although various embodiments have been described above, this does not mean that the measures in the various embodiments cannot be used advantageously in combination. Various substitutions and modifications can be made by those skilled in the art without departing from the scope of this disclosure, and all such substitutions and modifications should fall within the scope of this disclosure.

Claims

1. A method for accepting medical device department rooms, characterized in that, The method includes: A nuclear magnetic resonance gas probe is injected into the space to be evaluated using a gas probe injector to create an environmental disturbance between the nuclear magnetic resonance gas probe and the space to be evaluated, wherein the space to be evaluated includes a department room where medical devices are stored. Using a first nuclear magnetic resonance system arranged within the space to be evaluated, nuclear magnetic resonance data is acquired in the space to be evaluated, and nuclear magnetic resonance spectrum sequences of each spatial unit in the space to be evaluated are obtained. The space to be evaluated is divided into multiple spatial units, and the nuclear magnetic resonance spectrum sequence of each spatial unit includes multiple nuclear magnetic resonance spectrum data ordered according to the acquisition time. The nuclear magnetic resonance spectrum data is used to characterize the interaction between the nuclear magnetic resonance gas probe and the ambient gas in the spatial unit. Using a second nuclear magnetic resonance (NMR) system deployed within the space to be evaluated, diffusion-weighted NMR data are acquired to obtain diffusion-weighted imaging sequences for each spatial unit within the space to be evaluated. Each spatial unit's diffusion-weighted imaging sequence includes multiple diffusion-weighted images ordered according to the acquisition time. These diffusion-weighted images are used to characterize the gas diffusion state of the NMR gas probe within the spatial unit. The processor uses the nuclear magnetic resonance spectrum sequence and diffusion-weighted imaging sequence of each spatial unit in the space to be evaluated to assess the environmental state of the space to be evaluated, and obtains the assessment results.

2. The method according to claim 1, characterized in that, The spatial units are determined by using the first or second nuclear magnetic resonance system and three-dimensional spatial coding technology to divide the space to be evaluated into multiple spatial units according to a preset resolution. The process of acquiring nuclear magnetic resonance (NMR) data of the space to be evaluated using a first NMR system arranged within the space to be evaluated, and obtaining the NMR spectrum sequence of each spatial unit in the space to be evaluated, includes: The first nuclear magnetic resonance system is operated to excite the nuclear magnetic resonance gas probe, thereby driving the nuclear magnetic resonance gas probe to interact with the ambient gas; For each of the aforementioned spatial units, the interactions between gases within each spatial unit of the space to be evaluated are continuously collected, resulting in nuclear magnetic resonance (NMR) spectral data at multiple acquisition times; and The nuclear magnetic resonance spectrum data of the space unit are sorted according to the acquisition time to obtain the nuclear magnetic resonance spectrum sequence of the space unit.

3. The method according to claim 1, characterized in that, The method involves using a second nuclear magnetic resonance (NMR) system arranged within the space to be evaluated to acquire NMR diffusion-weighted data of the space to be evaluated, obtaining a diffusion-weighted imaging sequence for each spatial unit in the space to be evaluated, including: For each of the aforementioned spatial units, The control parameters of the second nuclear magnetic resonance system are configured according to the first preset parameter value, and the nuclear magnetic resonance gas probes in the space unit are excited by the second nuclear magnetic resonance system to obtain the first nuclear magnetic signals at each of the multiple acquisition times. The control parameters of the second nuclear magnetic resonance system are configured according to the second preset parameter value, and the nuclear magnetic resonance gas probes in the space unit are excited by the second nuclear magnetic resonance system to obtain the second nuclear magnetic signals at each of the multiple acquisition times. Based on the first and second NMR signals at each of the acquisition times, the gas diffusion state at each acquisition time is determined; and The multiple gas diffusion states are sorted according to the acquisition time to obtain the diffusion-weighted imaging sequence of the spatial unit.

4. The method according to claim 1, characterized in that, The process utilizes the processor to perform an environmental state assessment of the space to be assessed based on the nuclear magnetic resonance spectral sequences and diffusion-weighted imaging sequences of each spatial unit in the space to be assessed, obtaining assessment results, including: The processor determines the chemical shift sequence of the nuclear magnetic resonance gas probe based on the nuclear magnetic resonance spectrum sequence of each of the space units, wherein the chemical shift sequence includes multiple chemical shifts ordered according to the acquisition time, and the chemical shift at each acquisition time is determined based on the shift between the nuclear magnetic resonance frequency shown in the nuclear magnetic resonance spectrum at the acquisition time and the reference nuclear magnetic resonance frequency of the nuclear magnetic resonance gas probe; and The evaluation results are obtained based on the chemical shift sequence and the diffusion-weighted imaging sequence.

5. The method according to claim 4, characterized in that, The determination of the chemical shift sequence of the nuclear magnetic resonance gas probe based on the nuclear magnetic resonance spectral sequence of each of the spatial units includes: For each of the aforementioned acquisition times, Based on the nuclear magnetic resonance spectrum sequence, the nuclear magnetic resonance frequency at the acquisition time is determined; The relative shift between the nuclear magnetic resonance frequency and the reference nuclear magnetic resonance frequency is determined as the chemical shift; and The chemical shifts are sorted according to the acquisition time to obtain the chemical shift sequence.

6. The method according to claim 4, characterized in that, The evaluation result, obtained based on the chemical shift sequence and the diffusion-weighted imaging sequence, includes: For each of the aforementioned spatial units, Based on the chemical shift sequence, the physical properties of the components in the spatial unit are determined; Based on the diffusion-weighted imaging sequence, the geometric features of the constituent components in the spatial unit are determined; Based on the physical properties and geometric features, the sub-evaluation results for the spatial unit are determined; The evaluation result is obtained based on the identification information of each of the multiple spatial units, the mapping relationship between the identification information and the sequence, and the sub-evaluation results of each of the multiple spatial units. The mapping relationship between the identification information and the sequence includes the mapping relationship between the identification information of each of the multiple spatial units and the multiple chemical shift sequences, and the mapping relationship between the identification information of each of the multiple spatial units and the multiple diffusion-weighted imaging sequences.

7. The method according to claim 6, characterized in that, The determination of the physical properties of the constituent components in the space unit based on the chemical shift sequence includes: The displacement of the nuclear magnetic resonance frequency characterized by the chemical displacement of the nuclear magnetic resonance gas probe at each acquisition time is determined, and the displacement includes the nuclear magnetic resonance offset, the number of peaks, and the peak value. Based on the offset, the chemical composition of the space unit is determined; Based on the number of peaks, the number of independent environments in the spatial unit is determined; Based on the peak value of each peak, determine the containment capacity of each independent environment for the nuclear magnetic resonance gas probe; and The physical properties of the components in the space unit are determined based on the chemical composition, the number of independent environments, and the capacity of each independent environment to accommodate the nuclear magnetic resonance gas probe.

8. The method according to claim 6, characterized in that, Determining the geometric features of the constituent components in the spatial unit based on the diffusion-weighted imaging sequence includes: Based on the diffusion-weighted imaging sequence, the diffusion rate of the nuclear magnetic resonance gas probe within the space unit is determined; Based on the standard diffusion rate of the nuclear magnetic resonance gas probe and the diffusion rate, the tortuosity and connectivity of the space unit are determined; The geometric features are determined based on the degree of tortuosity and connectivity.

9. The method according to claim 1, characterized in that, The injection of a nuclear magnetic resonance gas probe into the space to be evaluated to create an environmental disturbance between the nuclear magnetic resonance gas probe and the space to be evaluated includes: At least one injection point is set on the boundary of the space to be evaluated; and The nuclear magnetic resonance gas probe is injected into the space to be evaluated from at least one of the injection points according to a preset injection method. When the boundary includes one of the injection points, the preset injection method includes at least one of the following: pulse injection and steady-state injection; When the boundary includes multiple injection points, the preset injection method is multi-point synchronous injection.

10. A medical device department room acceptance system, characterized in that, The system includes a gas probe injector, a first nuclear magnetic resonance system, a second nuclear magnetic resonance system, and a processor; The gas probe injector is configured to inject a nuclear magnetic resonance gas probe into the space to be evaluated, thereby creating an environmental disturbance between the nuclear magnetic resonance gas probe and the space to be evaluated, which includes a department room where medical devices are stored. The first nuclear magnetic resonance system is configured to acquire nuclear magnetic resonance data of the space to be evaluated, and obtain the nuclear magnetic resonance spectrum sequence of each spatial unit in the space to be evaluated. The space to be evaluated is divided into multiple spatial units, and the nuclear magnetic resonance spectrum sequence of each spatial unit includes multiple nuclear magnetic resonance spectrum data ordered according to the acquisition time. The nuclear magnetic resonance spectrum data is used to characterize the interaction between the nuclear magnetic resonance gas probe and the ambient gas in the spatial unit. The second nuclear magnetic resonance system is configured to acquire nuclear magnetic resonance diffusion-weighted data of the space to be evaluated, and obtain diffusion-weighted imaging sequences of each spatial unit in the space to be evaluated. The diffusion-weighted imaging sequence of the spatial unit includes multiple diffusion-weighted images ordered according to the acquisition time. The diffusion-weighted imaging is used to characterize the gas diffusion state of the nuclear magnetic resonance gas probe in the spatial unit. The processor is communicatively connected to the first and second nuclear magnetic resonance systems and is configured to receive nuclear magnetic resonance spectrum sequences of each spatial unit in the space to be evaluated sent by the first nuclear magnetic resonance system and diffusion-weighted imaging sequences of each spatial unit in the space to be evaluated sent by the second nuclear magnetic resonance system. Based on the nuclear magnetic resonance spectrum sequences and diffusion-weighted imaging sequences of each spatial unit in the space to be evaluated, the processor performs an environmental state assessment of the space to be evaluated and obtains an assessment result.

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