The invention relates to a protection method and a protection device of a power distribution network. The method comprises the following step of: arranging the protection devices used for carrying out logic control on opening and closing states on the breaker switch, linked switch and recloser of the power distribution network with phase voltages (UA, UB and UC) and phase currents (IA, IB and IC), wherein the logic control comprises voltage loss opening protection, hemi-voltage reclosing protection, current protection type voltage reclosing, latch-up separating protection, reclosing detection failure current protection, transient voltage latch-up protection, bilateral voltage latch-up closing protection, ring closing input withdrawing and hemi-voltage closing; and each protection device comprises a mutual inductor, a signal amplification circuit, a signal conditioning circuit (filtering circuit), an A/D (Analog/Digital) conversion module, an optical coupler, a communication module and a CPU (Central Processing Unit). By virtue of a plurality of creative protection logics and the corresponding protection devices, rapid fault region isolation and non-fault region power supply recovery for the power distribution network can be realized.