A multi-stage stirred pharmaceutical mixing tank

Abstract

This invention relates to the field of pharmaceutical technology and discloses a multi-stage stirring pharmaceutical mixing tank, comprising: a main tank body with several legs fixedly mounted on the bottom surface, a detachable sealing cover on the top, and a drug outlet pipe at the lower end of the side wall; several heaters fixedly mounted on the side wall of the main tank body; several auxiliary tank bodies fixedly mounted above the main tank body, with a connecting pipe and a drug inlet pipe fixedly mounted on the bottom and top surface respectively, the lower end of the connecting pipe extending into the main tank body; and a stirring frame including a main stirring rod and an auxiliary stirring rod. The main stirring rod is rotatably connected to the sealing cover and driven by a motor, with its lower end extending into the main tank body and fixedly mounted with several main stirring blades and a scraper. The auxiliary stirring rod is driven by the main stirring rod through a gearbox and extends into the auxiliary tank body and is connected with several auxiliary stirring blades. The advantages of this invention are: it has the functions of multi-stage stirring and pre-stirring, which can distribute the stirring pressure of the total stirring and avoid the problems of accumulation and incomplete mixing.

Description

Technical Field

[0001] This invention relates to the field of pharmaceutical technology, specifically to a multi-stage stirred pharmaceutical mixing tank. Background Technology

[0002] Pharmaceutical mixing tanks are specialized mixing and blending equipment commonly used in pharmaceutical production. They are primarily used for the mixing, dissolving, and reaction of materials in drug manufacturing. The entire unit is constructed of high-quality stainless steel, with a smooth, easy-to-clean surface and a sealed, clean structure. Equipped with a temperature control system for both heating and cooling operations, and featuring an adjustable-speed stirring mechanism, the equipment can thoroughly mix and blend various pharmaceutical solutions, raw materials, and excipients.

[0003] Currently available pharmaceutical mixing tanks on the market have relatively simple overall structural designs and generally lack practical functions such as staged mixing and secondary mixing. Production operations mostly employ a centralized mixing mode where all raw materials are fed into the tank at once, resulting in low overall mixing efficiency. Different raw materials cannot be processed in layers and steps according to their proportions and characteristics, making it difficult for materials with different properties to fully blend and penetrate, and the uniformity of material mixing fails to meet production standards. Furthermore, a single mixing mode easily leads to problems such as material clumping and incomplete mixing. Summary of the Invention

[0004] To solve the above-mentioned problems, this invention proposes a multi-stage stirring pharmaceutical mixing tank that has the functions of multi-stage stirring and pre-stirring, can share the stirring pressure of the total stirring, and avoids the problems of accumulation and incomplete mixing.

[0005] To solve the above-mentioned technical problems, the technical solution proposed by this invention is: a multi-stage stirred pharmaceutical mixing tank, comprising:

[0006] The main tank has several fixed legs on the bottom surface, a detachable sealing cover on the top, and a medicine outlet pipe at the lower end of the side wall, with a valve on the medicine outlet pipe.

[0007] Heaters are fixedly installed on the side wall of the main tank and are provided in several types;

[0008] A secondary tank is fixedly installed above the main tank and has several of them. A connecting pipe and a drug inlet pipe are fixedly installed on the bottom and top respectively. The lower end of the connecting pipe extends into the main tank. A control valve is installed on both the connecting pipe and the drug inlet pipe.

[0009] The stirring rack includes a main stirring rod and a secondary stirring rod. The main stirring rod is rotatably connected to the sealing cover and located on the central axis of the main tank. It is driven to rotate by a motor fixed to the sealing cover. The lower end of the main stirring rod extends into the main tank and is fixedly provided with several main stirring blades and a scraper. The scraper is set against the inner wall of the main tank. The secondary stirring rod corresponds one-to-one with the secondary tank and is connected to the main stirring rod through a gearbox. It extends into the secondary tank and is connected with several secondary stirring blades.

[0010] Furthermore, the support legs are located at the edge of the bottom surface of the main tank and are equidistantly distributed around the center of the bottom surface of the main tank.

[0011] Furthermore, the outer side of the upper end of the main tank is integrally formed with a receiving edge for a matching sealing cap. The edge of the sealing cap is connected and fixed to the receiving edge by several screws, and a sealing gasket is fixedly provided on its bottom edge. A handle is symmetrically fixed on the upper edge of the sealing cap.

[0012] Furthermore, the heater is a vertically elongated strip that fits closely to the side wall of the main tank, with its height matching the internal height of the main tank, and is equidistantly distributed around the central axis of the main tank.

[0013] Furthermore, the auxiliary tanks are equidistantly distributed around the central axis of the main tank, and an L-shaped bracket for fixing the auxiliary tanks is fixed above the main tank. A reinforcing inclined plate is fixed at the inner bend of the L-shaped bracket.

[0014] Furthermore, the upper end of the drug inlet pipe is bent horizontally outwards from the auxiliary tank.

[0015] Furthermore, a bevel gear one is fixedly provided on the motor drive end, and a bevel gear two that meshes with the bevel gear one is fixedly provided on the main stirring rod.

[0016] Furthermore, the main stirring blades are arranged in several groups at equal intervals, and the main stirring blades in the same group are arranged at equal intervals in a divergent manner around the main stirring rod. The main stirring blades are inclined and the upper wall is an arc surface.

[0017] Furthermore, the gearbox is located above the auxiliary tank. The upper ends of the main stirring rod and the auxiliary stirring rod extend into the gearbox and are respectively connected to the main gear and the auxiliary gear. The main gear meshes with each of the auxiliary gears. The main stirring rod and the auxiliary stirring rod are rotatably connected to the bottom surface of the gearbox. A top cover is threadedly fixed on the top of the gearbox, and a cooling fan is embedded in the center of the top cover.

[0018] Compared with existing technologies, the advantages of this invention are as follows: The equipment is equipped with a main tank and multiple auxiliary tanks. The auxiliary tanks can pre-mix the raw materials, pre-mixing various pharmaceutical raw materials to avoid the accumulation of large amounts of raw materials after direct input into the main tank, reducing the workload of the main mixing structure and achieving reasonable distribution of mixing pressure. The main and auxiliary mixing structures operate synchronously. The main mixing rod drives the main mixing blades to deeply mix the raw materials in the main tank. Multiple sets of inclined arc-shaped mixing blades expand the mixing range and increase the contact area, working in conjunction with a scraper to clean the tank wall and prevent raw materials from adhering and accumulating. The auxiliary mixing rods simultaneously mix the auxiliary tanks, ensuring the uniformity of the pre-mixed raw materials before feeding them into the main tank through a connecting pipe. This allows the main tank to only perform secondary fine mixing, eliminating the need to deal with the mixing pressure of large amounts of unmixed raw materials. The multi-stage mixing mode allows the raw materials to be processed in a stepped manner from input to final mixing. This avoids the uneven mixing caused by raw material accumulation during single-stage mixing and distributes the load of the main mixing through pre-mixing, ensuring efficient and uniform overall mixing, perfectly meeting the stringent requirements for raw material mixing precision in pharmaceutical processes. Attached Figure Description

[0019] Figure 1 This is a perspective view of the present invention;

[0020] Figure 2 This is the front view of the present invention;

[0021] Figure 3 This is a schematic diagram showing the state of the present invention after the top cover has been removed;

[0022] Figure 4 This is a schematic diagram of the lower end structure of the main stirring rod of the present invention.

[0023] As shown in the figure: 1. Main tank; 2. Support legs; 3. Sealing cover; 4. Discharge pipe; 5. Valve; 6. Heater; 7. Secondary tank; 8. Connecting pipe; 9. Inlet pipe; 10. Control valve; 11. Main stirring rod; 12. Secondary stirring rod; 13. Motor; 14. Main stirring blade; 15. Scraper; 16. Gearbox; 17. Handle; 18. L-shaped bracket; 19. Reinforcing inclined plate; 20. Bevel gear one; 21. Bevel gear two; 22. Main gear; 23. Secondary gear; 24. Cooling fan; 25. Top cover. Detailed Implementation

[0024] The present invention will now be described in further detail with reference to the accompanying drawings.

[0025] Combined with appendix Figure 1 Appendix Figure 2A multi-stage stirring pharmaceutical mixing tank includes: a main tank body 1, with a plurality of support legs 2 fixedly provided on the bottom surface. The support legs 2 are located at the edge of the bottom surface of the main tank body 1 and are equidistantly distributed around the center of the bottom surface of the main tank body 1, which can make the main tank body 1 more stable and avoid shaking caused by the shift of the center of gravity during the stirring process. At the same time, it ensures that the mixing tank is subjected to uniform force and extends the service life of the equipment.

[0026] Combined with appendix Figure 1 Appendix Figure 2 The main tank 1 is detachably equipped with a sealing cover 3 on its upper part, and a medicine outlet pipe 4 is provided at the lower end of the side wall. A valve 5 is provided on the medicine outlet pipe 4. The upper outer side of the main tank 1 is integrally formed with a receiving edge that matches the sealing cover 3. The edge of the sealing cover 3 is connected and fixed to the receiving edge by several screws. A sealing gasket is fixed on its bottom edge to improve the sealing performance of the tank and prevent leakage or contamination of pharmaceutical raw materials. The screw fixing method of the sealing cover 3 is convenient for disassembly and maintenance. Handles 17 are symmetrically fixed on the upper edge of the sealing cover 3 to facilitate the operation of taking off and putting on the sealing cover 3.

[0027] Combined with appendix Figure 1 Appendix Figure 3 Heater 6 is fixedly installed on the side wall of the main tank 1, and several heaters are provided. The heater 6 is a vertical strip that fits tightly against the side wall of the main tank 1. Its height is adapted to the internal height of the main tank 1. It is equidistantly distributed around the central axis of the main tank 1, which can realize uniform heating of raw materials in the tank, improve heating consistency, and meet the precise temperature requirements in the pharmaceutical process.

[0028] Combined with appendix Figure 1 Appendix Figure 2 A number of auxiliary tanks 7 are fixedly installed above the main tank 1. The auxiliary tanks 7 are equidistantly distributed around the central axis of the main tank 1. An L-shaped bracket 18 is fixedly installed above the main tank 1 to fix the auxiliary tanks 7. A reinforcing inclined plate 19 is fixedly installed at the inner bend of the L-shaped bracket 18 to enhance the stability of the auxiliary tanks 7 and prevent them from shaking during stirring. At the same time, the space is used reasonably to ensure the overall structure is compact.

[0029] Combined with appendix Figure 1 Appendix Figure 2 The bottom and top surfaces of the auxiliary tank 7 are respectively fixed with a connecting pipe 8 and a drug inlet pipe 9. The lower end of the connecting pipe 8 extends into the main tank 1. Both the connecting pipe 8 and the drug inlet pipe 9 are equipped with control valves 10. The upper end of the drug inlet pipe 9 is bent horizontally outward from the auxiliary tank 7 to facilitate the addition of pharmaceutical raw materials into the auxiliary tank 7 and to prevent spillage when adding raw materials.

[0030] Combined with appendix Figure 1 Appendix Figure 2The stirring rack includes a main stirring rod 11 and a secondary stirring rod 12. The main stirring rod 11 is rotatably connected to the sealing cover 3 and located on the central axis of the main tank 1. It is driven to rotate by a motor 13 fixed on the sealing cover 3. A bevel gear 20 is fixedly provided at the driving end of the motor 13. A bevel gear 21 that meshes with the bevel gear 20 is fixedly provided on the main stirring rod 11. The system has high transmission efficiency and stable power transmission, which can ensure that the main stirring rod 11 rotates at a uniform speed, ensuring uniform stirring effect and meeting the precise stirring requirements of pharmaceutical manufacturing.

[0031] Combined with appendix Figure 4 The lower end of the stirring frame extends into the main tank 1 and is fixedly provided with several main stirring blades 14 and scraper 15. The scraper 15 is set against the inner wall of the main tank 1. Several groups of main stirring blades 14 are arranged at equal intervals above and below. Several groups of main stirring blades 14 are arranged at equal intervals around the main stirring rod 11 in a divergent manner, which can expand the stirring range and improve the stirring uniformity of the raw materials in the main tank 1. In addition, the main stirring blades 14 are inclined and the upper wall is arc surface, which can increase the stirring contact area and improve the stirring efficiency.

[0032] Combined with appendix Figure 1 Appendix Figure 2 Appendix Figure 3 The auxiliary stirring rods 12 correspond one-to-one with the auxiliary tank 7 and are connected to the main stirring rod 11 via a gearbox 16. Several auxiliary stirring blades are connected to the auxiliary tank 7. The gearbox 16 is located above the auxiliary tank 7. The upper ends of the main stirring rod 11 and the auxiliary stirring rods 12 extend into the gearbox 16 and are respectively connected to a main gear 22 and a secondary gear 23. The main gear 22 meshes with each of the secondary gears 23. Both the main stirring rod 11 and the auxiliary stirring rod 12 are rotatably connected to the bottom surface of the gearbox 16, enabling the main stirring rod 11 to synchronously drive multiple auxiliary stirring rods 12, ensuring synchronous stirring. A top cover 25 is threadedly fixed to the top of the gearbox 16. A cooling fan 24 is embedded in the center of the top cover 25 to dissipate the heat generated by the gear transmission in a timely manner, extending the service life of the gearbox 16. The threaded top cover 25 also facilitates maintenance.

[0033] Specific implementation of the present invention: Before use, check the sealing performance of the main tank 1 and the auxiliary tank 7, and ensure that the sealing cover 3 is firmly fixed to the receiving edge of the main tank 1 by screws and that the sealing gasket fits tightly. At the same time, check that the valve 5 on the dispensing tube 4, the connecting tube 8 and the control valve 10 on the inlet tube 9 are in the closed state.

[0034] The corresponding pharmaceutical raw materials are added to each auxiliary tank 7 through the inlet pipe 9. After the addition is complete, the control valve 10 on the inlet pipe 9 is closed. The motor 13 is started. The motor 13 drives the main stirring rod 11 to rotate through the bevel gear 20 and bevel gear 21. The main stirring rod 11 then drives each auxiliary stirring rod 12 to rotate synchronously through the main gear 22 and auxiliary gear 23 in the gearbox 16, pre-stirring the raw materials in the auxiliary tank 7. At the same time, the heater 6 is started to preheat the main tank 1 to ensure that the temperature meets the pharmaceutical requirements.

[0035] After pre-mixing, open the control valve 10 on the connecting pipe 8 to send the pre-mixed raw materials in the auxiliary tank 7 into the main tank 1. The main stirring blades 14 on the main stirring rod 11 deeply mix the raw materials, and the scraper 15 adheres to the inner wall of the main tank 1 to clean the adhering raw materials. After mixing, turn off the motor 13 and the heater 6, open the valve 5 on the discharge pipe 4, and discharge the mixed raw materials through the discharge pipe 4. After discharge, close the valve 5 and clean the equipment.

[0036] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the term "connection" should be interpreted broadly, for example, it can be a fixed connection, a detachable connection, or an integral connection; those skilled in the art can understand the specific meaning of the above term in this invention according to the specific circumstances.

[0037] The present invention and its embodiments have been described above. This description is not restrictive, and the accompanying drawings are only one embodiment of the present invention; the actual structure is not limited thereto. In conclusion, if those skilled in the art are inspired by this description and design similar structures and embodiments without departing from the spirit of the invention, such designs should fall within the protection scope of the present invention.

Claims

1. A multi-stage stirred pharmaceutical mixing tank, characterized in that, include: The main tank (1) has several fixed support legs (2) on the bottom surface, a detachable sealing cover (3) on the top, and a medicine outlet pipe (4) at the lower end of the side wall. A valve (5) is provided on the medicine outlet pipe (4). Heater (6) is fixedly installed on the side wall of the main tank (1) and is provided with several; A secondary tank (7) is fixed above the main tank (1) and has several of them. A connecting pipe (8) and a medicine inlet pipe (9) are fixed on the bottom and top respectively. The lower end of the connecting pipe (8) extends into the main tank (1). A control valve (10) is provided on both the connecting pipe (8) and the medicine inlet pipe (9). The stirring rack includes a main stirring rod (11) and a secondary stirring rod (12). The main stirring rod (11) is rotatably connected to the sealing cover (3) and located on the central axis of the main tank (1). It is driven to rotate by a motor (13) fixed on the sealing cover (3). The lower end extends into the main tank (1) and is fixedly provided with several main stirring blades (14) and scrapers (15). The scrapers (15) are set against the inner wall of the main tank (1). The secondary stirring rod (12) corresponds one-to-one with the secondary tank (7) and is connected to the main stirring rod (11) through a gearbox (16). It extends into the secondary tank (7) and is connected with several secondary stirring blades.

2. The multi-stage stirred pharmaceutical mixing tank according to claim 1, characterized in that: The support legs (2) are located at the bottom edge of the main tank (1) and are distributed equidistantly around the center of the bottom of the main tank (1).

3. The multi-stage stirred pharmaceutical mixing tank according to claim 1, characterized in that: The upper outer side of the main tank (1) is integrally formed with a receiving edge for a matching sealing cover (3). The edge of the sealing cover (3) is connected and fixed to the receiving edge by several screws. A sealing gasket is fixedly provided on the bottom edge. A handle (17) is symmetrically fixed on the upper edge of the sealing cover (3).

4. A multi-stage stirred pharmaceutical mixing tank according to claim 1, characterized in that: The heater (6) is a vertical strip that fits tightly against the side wall of the main tank (1). Its height is adapted to the internal height of the main tank (1) and it is distributed equidistantly around the central axis of the main tank (1).

5. A multi-stage stirred pharmaceutical mixing tank according to claim 1, characterized in that: The auxiliary tanks (7) are distributed equidistantly around the central axis of the main tank (1). An L-shaped bracket (18) for fixing the auxiliary tanks (7) is fixed above the main tank (1). A reinforcing inclined plate (19) is fixed at the inner bend of the L-shaped bracket (18).

6. A multi-stage stirred pharmaceutical mixing tank according to claim 1, characterized in that: The upper end of the inlet pipe (9) is bent horizontally outwards towards the auxiliary tank (7).

7. A multi-stage stirred pharmaceutical mixing tank according to claim 1, characterized in that: The motor (13) is fixedly equipped with a bevel gear one (20) at the drive end, and the main stirring rod (11) is fixedly equipped with a bevel gear two (21) that meshes with the bevel gear one (20).

8. A multi-stage stirred pharmaceutical mixing tank according to claim 1, characterized in that: The main stirring blades (14) are arranged in several groups at equal intervals. The main stirring blades (14) in the same group are arranged at equal intervals in a divergent manner around the main stirring rod (11). The main stirring blades (14) are inclined and the upper wall is an arc surface.

9. A multi-stage stirred pharmaceutical mixing tank according to claim 1, characterized in that: The gearbox (16) is located above the auxiliary tank (7). The upper ends of the main stirring rod (11) and the auxiliary stirring rod (12) extend into the gearbox (16) and are respectively connected to the main gear (22) and the auxiliary gear (23). The main gear (22) meshes with each of the auxiliary gears (23). The main stirring rod (11) and the auxiliary stirring rod (12) are rotatably connected to the bottom surface of the gearbox (16). The gearbox (16) is threadedly fixed with an upper cover (25). A cooling fan (24) is embedded in the center of the upper cover (25).

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