Andiand liver peptide liver-protecting nutritional powder composition for postoperative recuperation

Abstract

This invention provides a giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recovery, belonging to the field of functional nutritional food technology. The method uses soybean peptide powder, collagen peptide, giant salamander peptide, and sea cucumber peptide as core active repair components, combined with inulin and yeast β-glucan to regulate the intestinal microecology, supplemented with yam, polygonatum, and goji berries to strengthen the body and nourish the internal organs, and combined with medium-chain triglycerides, flaxseed oil microcapsule powder, and coconut milk powder to provide easily absorbed high-energy nutrition after surgery. L-glutamine is added to repair the body's mucous membranes, and steviol glycosides are added to adjust the taste. This invention achieves five core effects through the synergistic combination of components: liver damage repair, postoperative physical recovery, improved intestinal absorption, enhanced immune function, and anti-oxidative stress. The raw materials in this composition are all food-grade medicinal and edible ingredients, with high safety and no side effects, which can quickly repair postoperative liver tissue damage, reduce liver metabolic pressure, and accelerate the body's recovery.

Description

Technical Field

[0001] This invention relates to the field of functional nutritional foods that are both food and medicine, specifically a giant salamander liver peptide liver-protecting nutritional powder composition for postoperative care. Background Technology

[0002] Surgical trauma, postoperative anesthetic drug metabolism, postoperative inflammatory stress, and prolonged bed rest are among the multiple factors that can cause persistent damage to the liver, a common health problem for postoperative patients. As a core organ for detoxification, metabolism, and nutrient transformation, the liver bears a heavy burden of metabolizing and breaking down anesthetic and anti-inflammatory drugs postoperatively. This makes it highly susceptible to liver cell damage, decreased liver metabolic function, and reduced liver antioxidant capacity, leading to a series of complications such as postoperative fatigue, poor appetite, poor nutrient absorption, weakened immunity, and slow recovery.

[0003] Currently available postoperative nutritional powders and protein powders have many technical shortcomings and cannot meet the specific needs of postoperative patients for liver protection and recovery. No targeted liver protection and repair function: Traditional nutritional powders only supplement basic protein and calories, and do not have repair components designed for postoperative drug-induced liver damage or stress-induced liver damage. They cannot improve liver metabolic pressure, and long-term use can easily increase the metabolic burden on the liver. Low nutrient absorption efficiency: Ordinary protein powder is mostly large molecule protein. Postoperative patients have weak gastrointestinal function and insufficient secretion of digestive enzymes, making it difficult to digest and absorb large molecule proteins, which can easily lead to problems such as bloating, food accumulation, and nutrient waste. A single nutritional system limits the recovery effect: conventional products only supplement protein and lack complex components such as immune regulation, intestinal conditioning, anti-oxidation, and vitality nourishment, which cannot systematically improve postoperative weakness, low immunity, oxidative stress damage and other problems. Active ingredients are easily lost and have poor compatibility: Some functional nutritional products add ingredients that are easily deactivated by high temperatures, resulting in serious loss of activity during processing. They also have a rough taste, poor solubility, and low patient compliance after surgery. Lack of postoperative-specific formulas: Existing nutritional products do not take into account the four core characteristics of postoperative "liver damage, physical weakness, intestinal weakness, and low immunity," resulting in poor formula targeting and an inability to achieve synergistic effects of organ repair and bodily recovery.

[0004] Giant salamander peptides are high-end bioactive peptides discovered in recent years. They possess excellent effects in liver cell repair, anti-oxidation, anti-stress, and promoting tissue regeneration. They can effectively activate the activity of liver metabolic enzymes, repair damaged liver cells, and reduce drug-induced liver damage, making them a high-quality active ingredient for postoperative liver protection. However, there are currently no liver-protecting nutritional powders on the market specifically developed for postoperative patients based on giant salamander peptides, and there is a lack of multi-component synergistic and precisely tailored compound formula systems for postoperative recovery.

[0005] Therefore, developing a postoperative salamander liver peptide liver-protecting nutritional powder composition that targets liver damage, is easily absorbed, has multiple synergistic effects, and is safe and gentle is a technical problem that urgently needs to be solved in the field of postoperative rehabilitation nutrition. Summary of the Invention

[0006] (a) Technical problems to be solved To address the shortcomings of existing technologies, this invention provides a giant salamander liver peptide liver-protecting nutritional powder composition for postoperative care, solving the following problems: 1. To address the problem that existing postoperative nutritional supplements lack targeted liver protection and cannot repair postoperative drug-induced or stress-induced liver damage; 2. It addresses the pain points of traditional protein supplements, such as large molecular weight and poor absorption, and is suitable for patients with weak digestive systems after surgery. 3. To address the issues of postoperative intestinal flora imbalance, malabsorption, weakened immunity, and prolonged recovery period in patients; 4. It addresses the problem that existing nutritional products offer only one type of nutrition and cannot simultaneously achieve liver repair, energy replenishment, immune system enhancement, and vitality nourishment; 5. Optimize the formula and preparation process to retain the core efficacy of active peptides, improve product solubility, taste and consumption compliance, and make it suitable for long-term postoperative care.

[0007] (II) Technical Solution To achieve the above objectives, the present invention provides the following technical solution: A liver-protecting nutritional powder composition using giant salamander liver peptides for postoperative recovery, comprising the following raw materials in weight percentages: 28-32% soybean peptide powder, 12-15% collagen peptide, 8-12% giant salamander peptide, 8-12% inulin, 6-10% coconut milk powder, 4-6% medium-chain triglycerides, 4-6% flaxseed oil microcapsule powder, 4-6% yam, 4-6% food flavoring, 3-5% sea cucumber peptide, 1-3% polygonatum, 1-3% wolfberry, 0.1-0.3% yeast β-glucan, and 0.1-0.3% steviol glycosides.

[0008] Further, the composition comprises the following raw materials in preferred weight percentages: 30% soybean peptide powder, 13.7% collagen peptide, 10% giant salamander peptide, 10% inulin, 8% coconut milk powder, 5% medium-chain triglycerides, 5% flaxseed oil microcapsule powder, 5% yam, 5% food flavoring (L-glutamine), 4% sea cucumber peptide, 2% polygonatum, 2% wolfberry, 0.2% yeast β-glucan, and 0.1% steviol glycosides.

[0009] Furthermore, the soybean peptide powder is a small molecule oligopeptide with an average molecular weight ≤1000Da, a protein content ≥98%, water solubility ≥99%, no bitter or astringent taste, and is easily absorbed directly by the human intestine.

[0010] Furthermore, the collagen peptide is a small molecule collagen peptide derived from fish skin, with an average molecular weight of 800~1200 Da; the giant salamander peptide is an active oligopeptide obtained from giant salamander muscle and liver through low-temperature enzymatic hydrolysis, filtration purification, and spray drying, with an average molecular weight ≤800 Da, and possesses hepatocyte repair and antioxidant activity.

[0011] Furthermore, the sea cucumber peptide is an active peptide prepared by enzymatic hydrolysis of the sea cucumber body wall, with an average molecular weight ≤1500Da, rich in sea cucumber mucopolysaccharides and active amino acids, and possesses immune regulation and body repair effects.

[0012] Furthermore, the yam, polygonatum, and wolfberry are all ultrafine powders obtained by low-temperature drying and ultra-micro pulverization, with a powder mesh size ≥800 mesh, free of coarse fiber impurities, ensuring the fineness and solubility of the powder, and suitable for absorption by the weak gastrointestinal tract after surgery.

[0013] Furthermore, the flaxseed oil microcapsule powder is prepared using a spray-drying microcapsule encapsulation process with an encapsulation rate of ≥95%, effectively locking in the activity of linolenic acid, preventing oxidation and inactivation, and exhibiting excellent water solubility; the medium-chain triglyceride is a food-grade MCT powder with a carbon chain length of 6~12 carbons, requiring no bile emulsification, and can be directly absorbed by the human body for energy.

[0014] Furthermore, the inulin is a long-chain prebiotic inulin with a purity ≥99%; the yeast β-glucan is a food-grade water-soluble glucan with a glucan content ≥85%; and the L-glutamine is a food-grade high-purity raw material with a purity ≥99%, which can repair intestinal mucosa and damaged tissues in the body.

[0015] A method for preparing a giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation includes the following steps: S1: Raw material pretreatment The yam, polygonatum, and wolfberry were ultra-finely pulverized and passed through an 800-mesh sieve, while the remaining powdered raw materials were sieved to remove impurities. S2: Low-temperature premixing Four types of active peptide raw materials, namely soybean peptide powder, collagen peptide, giant salamander peptide and sea cucumber peptide, are put into a three-dimensional mixer and premixed at low temperature and uniform speed for 15-20 minutes. S3: Stepwise compounding Add inulin, yeast beta-glucan, L-glutamine, plant ultrafine powder, lipid powder, and coconut milk powder in sequence, and mix them in a gradient stirring process; S4: Seasoning Homogenization Add steviol glycosides and stir at a constant speed to homogenize for 10-15 minutes; S5: Sterilization Packaging The finished nutritional powder is obtained by low-temperature irradiation sterilization and aseptic packaging in a sterile environment.

[0016] Furthermore, in steps S2 and S3, the mixing temperature is controlled at 20~25℃ and the stirring speed is 300~400r / min throughout the process to avoid high temperature damaging the activity of small molecule peptides and unsaturated fatty acid nutrients.

[0017] Furthermore, the composition exhibits excellent water solubility, dissolving rapidly in room temperature cold water without clumping or precipitation; it can target and repair postoperative drug-induced and stress-induced liver damage, regulate intestinal microecology, enhance the body's immunity, and rapidly replenish postoperative nutrition, making it suitable for long-term liver care and physical recovery in patients undergoing surgery, minimally invasive surgery, and tumor surgery.

[0018] (III) Beneficial Effects This invention provides a giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recovery. It has the following beneficial effects: 1. This invention provides a giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation. The raw materials are giant salamander peptide in combination with wolfberry and polygonatum, which can effectively repair liver cell damage caused by postoperative anesthetics and anti-inflammatory drugs, improve liver metabolism and antioxidant capacity, prevent postoperative liver function abnormalities, and have a fully small molecule active system. It is quick-dissolving in cold water and directly absorbed, suitable for the weakened digestive function after surgery, and can quickly replenish the body's required protein, lipids and trace elements, shortening the recovery period.

[0019] 2. This invention provides a giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation. The raw materials are inulin, yeast β-glucan, and yam, which work synergistically to regulate intestinal flora, repair mucosa, and nourish the spleen and stomach, thereby improving postoperative symptoms such as abdominal distension, anorexia, and physical weakness. The combination of sea cucumber peptide and yeast β-glucan bidirectionally regulates the body's immunity, reduces the risk of postoperative infection and inflammation recurrence, and enhances the body's disease resistance.

[0020] 3. This invention provides a giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation. The composition has a fine powder, dissolves quickly in cold water, has a mild and sweet taste, no bitter or unpleasant odor, and no calorie burden. It is suitable for long-term consumption by special groups such as those who have undergone surgery for diabetes or tumors. It can be widely used for the rehabilitation and recuperation of various postoperative groups, including those who have undergone surgical, orthopedic, minimally invasive, tumor, or hepatobiliary surgeries. It has extremely high industrialization and clinical application value. Detailed Implementation

[0021] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.

[0022] This invention strictly limits the mass percentage of each raw material to construct a six-layer synergistic system: a core liver-protecting and repairing layer, a polypeptide nutrition supplementation layer, an intestinal conditioning and absorption layer, a vital energy nourishing and strengthening layer, a high-energy lipid energy supply layer, and a taste adjustment and adaptation layer. Each component is precisely matched, complements and enhances each other, without conflict or antagonism, and is adapted to the special physiological state of postoperative patients.

[0023] Core liver-protecting and repairing component (giant salamander peptide 10%): Giant salamander small molecule active peptides are the core active ingredient, which can specifically act on liver tissue, activate the activity of alcohol dehydrogenase and acetaldehyde dehydrogenase, accelerate the metabolism of postoperative drug toxins, repair damaged liver cells, enhance the liver's antioxidant capacity, reduce malondialdehyde content, and increase glutathione levels, effectively improving postoperative drug-induced liver injury and oxidative stress liver injury, and reducing the metabolic pressure on the liver from the root.

[0024] This multi-component active peptide nutritional system (30% soybean peptides, 13.7% collagen peptides, and 4% sea cucumber peptides) is a blend of four small-molecule peptides. These peptides are low in molecular weight, highly water-soluble, and can be directly absorbed and utilized by the intestines without requiring gastrointestinal digestion. Soybean peptides replenish essential high-quality protein and repair body tissues; collagen peptides repair postoperative wounds and mucous membranes, and improve metabolism; sea cucumber peptides nourish vital energy, regulate immunity, and combat postoperative fatigue. The synergistic effect of these peptides comprehensively replenishes nutrients lost postoperatively, accelerating the body's repair process.

[0025] Intestinal microecological conditioning components (inulin 10%, yeast β-glucan 0.2%, L-glutamine 5%): Inulin, as a high-quality prebiotic, proliferates beneficial bacteria in the intestines and regulates the disordered intestinal flora after surgery; yeast β-glucan bidirectionally regulates the body's immunity and enhances the body's disease resistance after surgery; L-glutamine repairs the intestinal mucosal barrier, improves the problems of weak gastrointestinal tract and poor absorption after surgery, and fundamentally improves the efficiency of nutrient absorption.

[0026] The formula contains medicinal and edible ingredients to strengthen the body and nourish the body (5% yam, 2% polygonatum, and 2% goji berries): yam strengthens the spleen and stomach and replenishes the middle qi, making it suitable for postoperative spleen and stomach weakness; polygonatum nourishes yin and replenishes qi, strengthens the body and nourishes the source, improving postoperative weakness and fatigue; goji berries nourish the liver and kidneys, nourish the liver and improve eyesight, and help strengthen liver protection. These three medicinal and edible ingredients are mild and nourishing, non-irritating, and suitable for long-term postoperative recuperation.

[0027] High-energy, easily absorbed lipid components (8% coconut milk powder, 5% medium-chain triglycerides, 5% flaxseed oil microcapsule powder): Medium-chain triglycerides do not require bile emulsification, providing rapid energy without increasing the burden on the liver; Flaxseed oil microcapsule powder supplements Omega-3 unsaturated fatty acids, providing anti-inflammatory and antioxidant benefits and protecting liver cell membranes; Coconut milk powder provides natural plant lipids and trace elements, with a mild taste, improving product flavor, and supplementing essential lipid nutrition after surgery.

[0028] Taste-enhancing component (stevioside 0.1%): a natural zero-calorie sweetener that is calorie-free, does not raise blood sugar, does not increase the metabolic burden on the liver, improves the taste of powder, masks the slight bitterness of peptide ingredients, and enhances postoperative patient compliance.

[0029] This invention employs a low-temperature pretreatment, stepwise gradient mixing, and aseptic low-temperature sterilization process. The entire process is carried out at low temperatures to avoid damaging heat-sensitive active ingredients such as small molecule peptides and unsaturated fatty acids, thus maximizing the preservation of the raw material's bioactivity. The specific steps are as follows: S1: Raw material pretreatment The yam, polygonatum, and wolfberry are washed, dried at low temperature (55℃), and ultra-finely pulverized. They are then passed through an 800-mesh ultrafine sieve to remove coarse fiber impurities. All peptides and powder raw materials are sieved through a 100-mesh sieve to remove impurities, ensuring that the raw materials are fine and uniform. S2: Low-temperature premixing Four core active peptide raw materials—soybean peptide powder, collagen peptide, giant salamander peptide, and sea cucumber peptide—are put into a three-dimensional motion mixer. The temperature is controlled at 20-25℃, and the mixture is stirred at 350r / min for 18 minutes to achieve uniform mixing of active peptides. S3: Stepwise compounding Add the ingredients in the following order: "inorganic conditioning ingredients - plant nourishing ingredients - lipid ingredients". Add inulin, yeast β-glucan, L-glutamine, yam powder, polygonatum powder, wolfberry powder, medium chain triglycerides, flaxseed oil microcapsule powder, and coconut milk powder in sequence. Stir for 5 minutes after each batch of ingredients to ensure that the system is uniformly blended. S4: Seasoning Homogenization Finally, add a trace amount of steviol glycosides and stir at a low speed of 300r / min for 12 minutes to homogenize the mixture and ensure a uniform taste without any localized overly sweet areas. S5: Sterilization Packaging The product is sterilized by low-temperature irradiation with 60Co, and the sterilization dosage is controllable so as not to damage the product activity. Then, it is packaged, sealed and labeled in a sterile clean room to obtain the finished nutritional powder.

[0030] Example 1:

[0031] This embodiment provides a giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation, which is composed of the following raw materials in the indicated weight percentages: 30% soybean peptide powder, 13.7% collagen peptide, 10% giant salamander peptide, 10% inulin, 8% coconut milk powder, 5% medium-chain triglycerides, 5% flaxseed oil microcapsule powder, 5% yam, 5% food flavoring (L-glutamine), 4% sea cucumber peptide, 2% polygonatum, 2% wolfberry, 0.2% yeast β-glucan, and 0.1% steviol glycosides.

[0032] Among them, the average molecular weight of soybean peptides is 900 Da; the average molecular weight of collagen peptides is 1000 Da; the average molecular weight of giant salamander peptides is 700 Da; the average molecular weight of sea cucumber peptides is 1200 Da; the plant powder is 800 mesh; and the encapsulation rate of flaxseed oil microcapsule powder is 96%. The purity of each raw material meets the national standards for food grade.

[0033] The preparation process is as follows: S1: Raw material pretreatment The yam, polygonatum, and wolfberry are washed, dried at low temperature (55℃), and ultra-finely pulverized. They are then passed through an 800-mesh ultrafine sieve to remove coarse fiber impurities. All peptides and powder raw materials are sieved through a 100-mesh sieve to remove impurities, ensuring that the raw materials are fine and uniform. S2: Low-temperature premixing Four core active peptide raw materials—soybean peptide powder, collagen peptide, giant salamander peptide, and sea cucumber peptide—are put into a three-dimensional motion mixer. The temperature is controlled at 22℃, and the mixture is stirred at 350r / min for 18 minutes to achieve uniform mixing of active peptides. S3: Stepwise compounding Add the ingredients in the following order: "inorganic conditioning ingredients - plant nourishing ingredients - lipid ingredients". Add inulin, yeast β-glucan, L-glutamine, yam powder, polygonatum powder, wolfberry powder, medium chain triglycerides, flaxseed oil microcapsule powder, and coconut milk powder in sequence. Stir for 5 minutes after each batch of ingredients to ensure that the system is uniformly blended. S4: Seasoning Homogenization Finally, add a trace amount of steviol glycosides and stir at a low speed of 300r / min for 12 minutes to homogenize the mixture and ensure a uniform taste without any localized overly sweet areas. S5: Sterilization Packaging The product is sterilized by low-temperature irradiation with 60Co, and the sterilization dosage is controllable so as not to damage the product activity. Then, it is packaged, sealed and labeled in a sterile clean room to obtain the finished nutritional powder.

[0034] Example 2: Enhanced Liver Protection After Severe Postoperative Care Based on Example 1, this formula was slightly modified to suit patients who have undergone severe surgery or have significant liver damage. The total proportion of the formula remained at 100%, but the proportions of the components were slightly adjusted: giant salamander peptide was increased to 12%, inulin was increased to 12%, soybean peptide powder was slightly adjusted to 28%, and collagen peptide was slightly adjusted to 11.7%. The proportions of the remaining components, raw material parameters, and preparation process were completely consistent with Example 1, which enhanced the liver repair and intestinal detoxification capabilities.

[0035] Example 3: Mild Post-Minimally Invasive Post-operative Care Based on Example 1, this formula is adapted for minimally invasive surgery and people with mild physical weakness. The total proportion of the formula is 100%, with slight adjustments to the components: coconut milk powder is increased to 10%, medium-chain triglycerides are increased to 6%, collagen peptides are slightly adjusted to 12.7%, and giant salamander peptides are slightly adjusted to 8%. The proportions of the remaining components and process parameters remain unchanged. The taste is more mellow and the energy supply is gentler, making it suitable for long-term daily conditioning.

[0036] Comparative Example 1: It uses commercially available postoperative compound protein powder (mainly high molecular weight whey protein, without giant salamander peptides, liver-protecting components, or prebiotic conditioning components).

[0037] Comparative Example 2: The giant salamander peptide component was removed, but the rest of the formula and process were completely consistent with Example 1, verifying the core liver-protecting efficacy of the giant salamander peptide.

[0038] Comparative Example 3: The conventional high-temperature stirring process (mixing at 80°C) was used, and the formula was the same as in Example 1, to verify the effect of the low-temperature preservation process.

[0039] Performance testing: This test selected participants with mild postoperative liver function abnormalities and general weakness, divided them into 6 groups, and administered the treatment for 30 consecutive days with a unified diet and lifestyle. Key indicators such as liver function, nutrient absorption rate, immunity, and intestinal status were measured. The test results are shown in the table below.

[0040] The test results above show that 1. The overall performance of the three sets of embodiments of the present invention is far superior to all comparative examples. Among them, Embodiment 1 is the universal optimal formula with balanced indicators, suitable for the vast majority of postoperative patients; Embodiment 2 has the best liver protection and repair effect, suitable for patients with severe liver damage after surgery; Embodiment 3 has the best taste and mildness, suitable for daily care after minimally invasive surgery, covering the postoperative rehabilitation needs of all scenarios.

[0041] 2. Comparative Example 1 (traditional protein powder) has no liver-protecting or intestinal-regulating effects, low nutrient absorption rate, can only supplement basic calories, cannot improve postoperative liver damage and physical weakness, and has extremely poor recovery effect.

[0042] 3. Comparative Example 2 (without giant salamander peptide) showed good nutrient absorption and intestinal conditioning effects, but the rate of improvement in liver function decreased significantly, directly verifying that giant salamander peptide is the core functional component for targeted liver protection in this invention.

[0043] 4. The efficacy indicators of Comparative Example 3 (high temperature process) showed a significant decrease, proving that the low temperature stepwise mixing process of this invention can effectively preserve the bioactivity of active peptides and functional components, which is the key to ensuring the core efficacy of the product.

[0044] The formula of this invention is scientifically formulated and the process is stable. It can effectively repair postoperative liver damage, improve nutrient absorption, improve postoperative weakness, and regulate the intestines and immunity. It solves many pain points of existing postoperative nutritional products and has extremely high clinical conditioning value and industrialization prospects.

[0045] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

Claims

1. A giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation, characterized in that, It is composed of the following raw materials in the indicated weight percentages: 28-32% soybean peptide powder, 12-15% collagen peptide, 8-12% giant salamander peptide, 8-12% inulin, 6-10% coconut milk powder, 4-6% medium-chain triglycerides, 4-6% flaxseed oil microcapsule powder, 4-6% yam, 4-6% food flavoring, 3-5% sea cucumber peptide, 1-3% polygonatum, 1-3% wolfberry, 0.1-0.3% yeast β-glucan, and 0.1-0.3% steviol glycosides.

2. The giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation according to claim 1, characterized in that, The soybean peptide powder is a small molecule oligopeptide with an average molecular weight ≤1000Da, a protein content ≥98%, water solubility ≥99%, no bitter or astringent taste, and is easily absorbed directly by the human intestine.

3. The giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation according to claim 1, characterized in that, The collagen peptides are small molecule collagen peptides derived from fish skin, with an average molecular weight of 800~1200 Da; the giant salamander peptides are active oligopeptides obtained from giant salamander muscle and liver through low-temperature enzymatic hydrolysis, filtration purification, and spray drying, with an average molecular weight ≤800 Da, and possess liver cell repair and antioxidant activities.

4. The giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation according to claim 1, characterized in that, The sea cucumber peptides are active peptides prepared by enzymatic hydrolysis of the sea cucumber body wall, with an average molecular weight ≤1500Da. They are rich in sea cucumber mucopolysaccharides and active amino acids, and have immune-regulating and body-repairing effects.

5. The giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation according to claim 1, characterized in that, The yam, polygonatum, and wolfberry are all ultra-fine powders obtained by low-temperature drying and ultra-micro pulverization, with a powder mesh size ≥800 mesh, free of coarse fiber impurities, ensuring the fineness and solubility of the powder, and suitable for absorption by the weak gastrointestinal tract after surgery.

6. The giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation according to claim 1, characterized in that, The flaxseed oil microcapsule powder is prepared using a spray-drying microcapsule encapsulation process with an encapsulation rate of ≥95%, effectively locking in the activity of linolenic acid, preventing oxidation and inactivation, and exhibiting excellent water solubility; the medium-chain triglyceride is a food-grade MCT powder with a carbon chain length of 6~12 carbons, which does not require bile emulsification and can be directly absorbed by the human body for energy.

7. The giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation according to claim 1, characterized in that, The inulin is a long-chain prebiotic inulin with a purity of ≥99%; the yeast β-glucan is a food-grade water-soluble glucan with a glucan content of ≥85%; and the L-glutamine is a food-grade high-purity raw material with a purity of ≥99%, which can repair intestinal mucosa and damaged tissues in the body.

8. A method for preparing a giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation, characterized in that, Includes the following steps: S1: Raw material pretreatment The yam, polygonatum, and wolfberry were ultra-finely pulverized and passed through an 800-mesh sieve, while the remaining powdered raw materials were sieved to remove impurities. S2: Low-temperature premixing Four types of active peptide raw materials, namely soybean peptide powder, collagen peptide, giant salamander peptide and sea cucumber peptide, are put into a three-dimensional mixer and premixed at low temperature and uniform speed for 15-20 minutes. S3: Stepwise compounding Add inulin, yeast beta-glucan, L-glutamine, plant ultrafine powder, lipid powder, and coconut milk powder in sequence, and mix them in a gradient stirring process; S4: Seasoning Homogenization Add steviol glycosides and stir at a constant speed to homogenize for 10-15 minutes; S5: Sterilization Packaging The finished nutritional powder is obtained by low-temperature irradiation sterilization and aseptic packaging in a sterile environment.

9. The method for preparing the giant salamander liver peptide liver-protecting nutritional powder composition for postoperative recuperation according to claim 8, characterized in that, In steps S2 and S3, the mixing temperature is controlled at 20~25℃ and the stirring speed is 300~400r / min throughout the process to avoid high temperature damaging the activity of small molecule peptides and unsaturated fatty acid nutrients.

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