Supermicro Tongxinluo Chinese herbal composite and its new usage

A composition, Tongxinluo technology, applied in the field of ultra-fine Tongxinluo traditional Chinese medicine composition, can solve the problems of inability to destroy cell structure, immature extraction and refining methods, uneven mixing, etc., and achieve improvement of blood lipids and vascular lumen stenosis , reduce the reflow area and infarct size, and reduce the effect of AngII level

CN1954825AActive Publication Date: 2007-05-02HEBEI YILING MEDICINE INST
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2007-05-02

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Abstract

An application of the Chinese medicine 'Superfine Tongxinluo' in relaxing the vascular endothelial injury caused by atherosclerosis, decreasing the cardiac infarction range after AMI reperfusion, preventing hyperlipemia and atherosclerosis, and treating arteria coronaria spasm, pile, thromboangiitis obliterans, platelet coagulation, etc is disclosed.
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Description

technical field

[0001] The invention relates to a superfine Tongxinluo traditional Chinese medicine composition and several new uses thereof, belonging to the field of traditional Chinese medicine. Background technique

[0002] Coronary arteriosclerotic heart disease refers to the formation of plaque on the coronary artery wall, resulting in stenosis or blockage of the vessel lumen, causing myocardial ischemia, hypoxia, and coronary artery spasm, which are classified into the category of ischemic heart disease.

[0003] Tongxinluo Capsule is a three-class Chinese patent medicine developed and invented by Professor Wu Yiling and has obtained a patent (ZL01131203.3) for treating cardiovascular and cerebrovascular diseases. Professor Wu Yiling pioneered the use of TCM collateral disease theory to explore the pathogenesis of coronary heart disease, and applied five insect medicines, including scorpion, centipede, earth element, leech and cicada slough, to the treatment of corona...

Examples

Embodiment

[0023] Embodiment Pharmacological experiment 1

[0024] Effect of Tongxinluo Superfine Powder on Endothelial Function Damage of Atherosclerosis

[0025] The purpose of the experiment To observe the effect of Tongxinluo superfine powder treatment on the changes of vascular endothelial function in atherosclerosis (AS), so as to evaluate the therapeutic effect of Tongxinluo superfine powder on AS.

[0026] Preparation and grouping of animal models 56 healthy male New Zealand white rabbits (body weight 2.5-3.0Kg) were randomly divided into two groups: normal diet group (fed with common feed, 6), and high-fat diet group (fed with high-cholesterol and high-fat feed, 5), after 8 weeks high-fat diet to form atherosclerosis model, and then they were randomly divided into 6 groups: continue high-fat diet group (10), ordinary Tongxinluo group 0.5g / kg, superfine powder Tongxin Network group (1, 0.5, 0.2g / kg), fed for 12 weeks.

[0027] Indicator detection

[0028] Deter...