Cleaning device for unfrozen umbilical cord blood hematopoietic stem cells
By designing an automated umbilical cord blood hematopoietic stem cell cleaning device, a rotary motor and water spray head are used to automatically clean the inner and outer walls of the umbilical cord blood hematopoietic stem cell storage bottle after thawing. This solves the problems of slow and incomplete cleaning speed in the existing technology, improves cleaning efficiency, and prevents contamination.
Patent Information
- Application Number
- CN202420745195.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-11
- Publication Date
- 2024-12-13
- Estimated Expiration
- 2034-04-11
Smart Images

Figure CN222153289U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of medical devices, in particular to a cleaning device for thawing umbilical cord blood hematopoietic stem cells. Background Art
[0002] Umbilical cord blood hematopoietic stem cells can be used for hematopoietic stem cell transplantation to treat many diseases of the blood system and immune system, and have important clinical application value. Umbilical cord blood hematopoietic stem cells are mostly stored in the form of liquid nitrogen in the umbilical cord blood bank, and need to be thawed and revived in clinical applications; if the cryoprotectant is removed by centrifugation, the thawed umbilical cord blood can be placed at 4°C for 24 hours. Because the centrifugal removal of cryoprotectant will cause a large loss of umbilical cord blood cells, and the dilution method can only extend the storage time to a limited extent, the clinical application of umbilical cord blood adopts the method of immediate infusion after thawing, which requires the umbilical cord blood to be transported to clinical medical institutions in advance in storage bottles by liquid nitrogen low-temperature transportation, and then thawed and revived in the ward, and directly extracted for injection. The following problems exist in the existing technology:
[0003] Because umbilical cord blood hematopoietic stem cells are injected into storage bottles during transportation, and the storage equipment is placed in liquid nitrogen for low-temperature transportation, and after the umbilical cord blood hematopoietic stem cells inside the storage bottle are extracted and injected, there will still be some residues in the bottle, so it needs to be cleaned in time, and the existing cleaning method only relies on manual flushing and wiping with a flushing gun, resulting in a slow cleaning speed, and the umbilical cord blood hematopoietic stem cells remaining in the bottle are coagulated due to not being cleaned for a long time, and it is difficult to clean them. Utility Model Content
[0004] The utility model provides a cleaning device for thawing umbilical cord blood hematopoietic stem cells to solve the problems raised in the above-mentioned background technology.
[0005] In order to solve the above technical problems, the technical solution adopted by the utility model is:
[0006] A cleaning device for thawing umbilical cord blood hematopoietic stem cells comprises a cleaning box, a glass movable door is movably installed on the front side of the cleaning box, a drainage hole penetrating to the inner cavity is opened at the bottom of the cleaning box, a waste water tank is fixedly installed on the top of the cleaning box, the waste water tank is connected with the inner cavity of the cleaning box via the drainage hole, a bottle body positioning mechanism is arranged on the rear side of the inner wall of the drainage hole, and a flushing clamping mechanism is arranged on the top of the inner wall of the cleaning box.
[0007] A water pump is fixedly installed on the top of the cleaning box, and a fixed long tube is fixedly connected to the output end of the water pump at the lower left side. The bottle body positioning mechanism includes a fixed hollow bracket, the rear end of the fixed hollow bracket penetrates to the rear side of the cleaning box and is fixedly connected to the output end of the fixed long tube, the front end of the fixed hollow bracket is penetrated and fixedly connected to a base box, and the top of the base box is penetrated and fixedly connected to a bottle body placement box.
[0008] A further improvement of the technical solution of the utility model lies in that: a plurality of rotating motors are fixedly installed in a circular array at the eccentric bottom of the inner wall of the bottle body placement box, the output shafts of several of the rotating motors all penetrate through the top of the bottle body placement box and are fixedly installed with rotating rods, cleaning brushes are fixedly installed on opposite sides of the outer walls of several of the rotating rods, a sponge head is fixedly installed on the top of the rotating rod, water spray heads are provided on the front and rear sides of several of the rotating rods, and the water spray heads are all fixedly connected with the top of the bottle body placement box.
[0009] A further improvement of the technical solution of the utility model lies in that: the flushing clamping mechanism includes an electric push rod, which is fixedly installed at the top center of the inner wall of the cleaning box, and a clamping hollow disk is fixedly installed at the bottom output end of the electric push rod, and a water supply hose is fixedly connected to the upper left output end of the water pump, and the output end of the water supply hose penetrates into the inner cavity of the cleaning box and is fixedly connected to the top of the clamping hollow disk, and a plurality of extrusion cylinders are fixedly connected in a circular array at the eccentric bottom of the clamping hollow disk, and the plurality of extrusion cylinders are respectively located above a plurality of rotating rods, and the bottoms of the plurality of extrusion cylinders are fixedly connected with flushing ports.
[0010] A further improvement of the technical solution of the utility model is that an inclined guide plate is fixedly installed on the right side of the inner wall of the wastewater tank, a sewage pipe is fixedly connected to the left side of the bottom of the wastewater tank, and the top of the sewage pipe is connected to the left side of the inner cavity of the wastewater tank.
[0011] Due to the adoption of the above technical solution, the utility model has achieved the following technical progress compared with the prior art:
[0012] 1. The utility model provides a cleaning device for thawed cord blood hematopoietic stem cells. Through the cooperation of the bottle positioning mechanism and the flushing and clamping mechanism, the inner and outer walls of the thawed cord blood hematopoietic stem cell storage bottle can be quickly cleaned without manual repeated cleaning, thereby improving the cleaning efficiency.
[0013] 2. The utility model provides a cleaning device for thawing umbilical cord blood hematopoietic stem cells. Through the cooperation of the cleaning box, the glass movable door and the waste water tank, the glass movable door can be closed when the cleaning box is in use, thereby preventing the splashing of the cleaning water source, and the cleaning water can be concentrated into the waste water tank for discharge to avoid polluting the cleaning environment. BRIEF DESCRIPTION OF THE DRAWINGS
[0014] Figure 1 It is an overall schematic diagram of the structure of the utility model;
[0015] Figure 2 This is a schematic diagram of the bottle positioning mechanism of the utility model structure;
[0016] Figure 3 It is a cross-sectional schematic diagram of a bottle body placement box of the utility model structure;
[0017] Figure 4 It is a schematic diagram of the flushing and clamping mechanism of the utility model structure;
[0018] Figure 5 This is a schematic diagram of a wastewater tank of the utility model structure.
[0019] In the figure: 1. cleaning box; 11. water pump; 111. fixed long tube; 112. water supply hose; 2. glass movable door; 3. drainage hole; 4. bottle body positioning mechanism; 41. fixed hollow bracket; 42. base box; 43. bottle body placement box; 431. rotating motor; 432. rotating rod; 433. cleaning brush; 434. sponge head; 435. water spray head; 5. flushing clamping mechanism; 51. electric push rod; 52. clamping hollow disk; 53. extrusion cylinder; 54. flushing port; 6. waste water tank; 61. inclined guide plate; 62. sewage pipe. DETAILED DESCRIPTION
[0020] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.
[0021] like Figure 1 , Figure 2 As shown, the utility model provides a cleaning device for thawing umbilical cord blood hematopoietic stem cells, comprising a cleaning box 1, a glass movable door 2 is movably installed on the front side of the cleaning box 1, a water hole 3 penetrating to the inner cavity is opened at the bottom of the cleaning box 1, a waste water tank 6 is fixedly installed on the top of the cleaning box 1, the waste water tank 6 is connected with the inner cavity of the cleaning box 1 by the water hole 3, a bottle body positioning mechanism 4 is arranged on the rear side of the inner wall of the water hole 3, a flushing clamping mechanism 5 is arranged on the top of the inner wall of the cleaning box 1, a water pump 11 is fixedly installed on the top of the cleaning box 1, a fixed long tube 111 is fixedly connected to the output end of the left lower side of the water pump 11, the bottle body positioning mechanism 4 comprises a fixed hollow bracket 41, the rear end of the fixed hollow bracket 41 penetrates to the rear side of the cleaning box 1 and is fixedly connected to the output end of the fixed long tube 111, the front end of the fixed hollow bracket 41 is penetrated and fixedly connected to a base box 42, and the top of the base box 42 is penetrated and fixedly connected to a bottle body placement box 43;
[0022] During cleaning, the water source is injected into the fixed hollow bracket 41 through the fixed long tube 111 by connecting the input end of the water pump 11 to the water pipe, and then the water is filled into the inner cavity of the bottle placement box 43 through the base box 42, and the glass movable door 2 is used to facilitate observation of the cleaning condition inside the cleaning box 1.
[0023] like Figure 3 , Figure 4 As shown, a plurality of rotating motors 431 are fixedly installed in a circular array at the eccentric position of the bottom of the inner wall of the bottle body placement box 43, the output shafts of the plurality of rotating motors 431 all penetrate the top of the bottle body placement box 43 and are fixedly installed with rotating rods 432, cleaning brushes 433 are fixedly installed on opposite sides of the outer walls of the plurality of rotating rods 432, a sponge head 434 is fixedly installed on the top of the rotating rod 432, and water spray heads 435 are provided on the front and rear sides of the plurality of rotating rods 432, and the water spray heads 435 are all fixedly connected with the top of the bottle body placement box 43, and the flushing clamping mechanism 5 includes an electric push rod 51, the electric push rod 51 is fixedly installed at the center of the top of the inner wall of the cleaning box 1, and a clamping hollow disk 52 is fixedly installed at the bottom output end of the electric push rod 51. A water delivery hose 112 is fixedly connected to the upper left output end of the water pump 11. The output end of the water delivery hose 112 penetrates the inner cavity of the cleaning box 1 and is fixedly connected to the top of the clamping hollow disk 52. A plurality of extrusion cylinders 53 are fixedly connected in a circular array at the eccentric bottom of the clamping hollow disk 52. The plurality of extrusion cylinders 53 are respectively located above the plurality of rotating rods 432, and the bottoms of the plurality of extrusion cylinders 53 are fixedly connected with flushing ports 54;
[0024] When it is necessary to clean the bottle of hematopoietic stem cells of the umbilical cord blood after extraction and thawing, the bottles are inverted one by one and inserted into the rotating rod 432 on the top of the bottle placement box 43, and the soft characteristics of the sponge head 434 and the cleaning brush 433 are used to temporarily fix the bottle under the squeezing of the sponge head 434 and the cleaning brush 433, and the cleaning brush 433 and the sponge head 434 are made to fit tightly against the inner wall of the bottle, and the bottle placement box 43 filled with water is used to rinse the inner wall of the bottle through the water spray heads 435 on the front and rear sides of the rotating rod 432, and at the same time, the electric push rod 51 is started to drive the clamping hollow disk 52 to descend, and the multiple squeezing cylinders 53 at the bottom of the clamping hollow disk 52 can be used to squeeze the top of the bottle on the outer side of the multiple rotating rods 432, so that the bottle is firmly fixed, and at the same time, the rotating motor 431 in the inner cavity of the bottle placement box 43 is started. The rotating rod 432 can be driven to drive the cleaning brush 433 and the sponge head 434 to rotate and clean the inner wall of the bottle body, and the inner wall of the bottle body can be effectively cleaned by cooperating with the water spray head 435 to rinse the inner wall of the bottle body. At the same time, when the outer wall of the bottle body needs to be cleaned, the electric push rod 51 drives the clamping hollow plate 52 to rise, releases the clamping and fixation of the bottle body, and uses the water supply hose 112 connected to the other output end of the water pump 11 to inject water into the inner cavity of the clamping hollow plate 52, and uses the hollow extrusion cylinder 53 to flush the outer wall of the bottle body below through the flushing port 54. At this time, since the bottle body is no longer squeezed and fixed by the extrusion cylinder 53, the cleaning brush 433 can be used to squeeze the inner wall of the bottle body under the rotation of the rotating rod 432, so as to drive the bottle body to rotate, so that the outer wall of the bottle body is evenly rinsed. Because there is no umbilical cord blood hematopoietic stem cell residue on the outer wall of the bottle body, a simple rinse is sufficient.
[0025] like Figure 5 As shown, an inclined guide plate 61 is fixedly installed on the right side of the inner wall of the wastewater tank 6, and a sewage pipe 62 is fixedly connected to the left side of the bottom of the wastewater tank 6, and the top of the sewage pipe 62 is connected to the left side of the inner cavity of the wastewater tank 6;
[0026] Since the bottle body is installed inverted, the sewage generated during cleaning in the cleaning box 1 will be concentrated into the waste water tank 6 through the drainage hole 3 opened at the bottom of the cleaning box 1, and will be concentrated to the left side of the inner cavity of the waste water tank 6 by the inclined guide plate 61, and can be discharged through the sewage pipe 62.
[0027] The working principle of the cleaning device after thawing of umbilical cord blood hematopoietic stem cells will be described in detail below.
[0028] like Figure 1-5As shown, when it is necessary to clean the bottle of hematopoietic stem cells extracted from the thawed umbilical cord blood, the bottles are inverted one by one and inserted into the rotating rod 432 on the top of the bottle placement box 43, and the soft characteristics of the sponge head 434 and the cleaning brush 433 are used to temporarily fix the bottle under the squeezing of the sponge head 434 and the cleaning brush 433, and the cleaning brush 433 and the sponge head 434 are made to cling to the inner wall of the bottle. During cleaning, the input end of the water pump 11 is connected to the water pipe, so that the water source is injected into the fixed hollow bracket 41 through the fixed long tube 111, and the inner cavity of the bottle placement box 43 is filled through the base box 42, and the inner wall of the bottle is rinsed through the water spray heads 435 on the front and rear sides of the rotating rod 432. At the same time, the electric push rod 51 is started to drive the clamping hollow disk 52 to descend, and the top of the bottle covered on the outer side of the plurality of rotating rods 432 can be squeezed by using the plurality of squeezing cylinders 53 at the bottom of the clamping hollow disk 52, so that the bottle is firmly fixed. The bottle body is firmly fixed, and the rotating motor 431 in the inner cavity of the bottle body placement box 43 is started at the same time to drive the rotating rod 432 to drive the cleaning brush 433 and the sponge head 434 to rotate and clean the inner wall of the bottle body, and cooperate with the water spray head 435 to rinse the inner wall of the bottle body, so that the inner wall of the bottle body is effectively cleaned. At the same time, when the outer wall of the bottle body needs to be cleaned, the electric push rod 51 drives the clamping hollow plate 52 to rise, releases the clamping fixation of the bottle body, and uses the water delivery hose 112 connected to the other output end of the water pump 11 to inject water into the inner cavity of the clamping hollow plate 52, and uses the hollow extrusion cylinder 53 to flush the outer wall of the bottle body below through the flushing port 54. At this time, since the bottle body is no longer squeezed and fixed by the extrusion cylinder 53, the cleaning brush 433 can be used to squeeze the inner wall of the bottle body under the rotation of the rotating rod 432, so that the bottle body is driven to rotate, so that the outer wall of the bottle body is evenly rinsed. Because there is no umbilical cord blood hematopoietic stem cell residue on the outer wall of the bottle body, a simple rinse is sufficient.
[0029] The above generally describes the present invention in detail, but it is obvious to a person skilled in the art that some modifications or improvements can be made to the present invention. Therefore, modifications or improvements that do not depart from the spirit of the present invention are within the scope of protection of the present invention.
Claims
1. A cleaning device for thawing umbilical cord blood hematopoietic stem cells, comprising a cleaning box (1), characterized in that: A glass movable door (2) is movably installed on the front side of the cleaning box (1); a water hole (3) penetrating to the inner cavity is provided at the bottom of the cleaning box (1); a waste water tank (6) is fixedly installed on the top of the cleaning box (1); the waste water tank (6) is connected to the inner cavity of the cleaning box (1) via the water hole (3); a bottle body positioning mechanism (4) is provided on the rear side of the inner wall of the water hole (3); and a flushing clamping mechanism (5) is provided on the top of the inner wall of the cleaning box (1); A water pump (11) is fixedly installed on the top of the cleaning box (1), and a fixed long tube (111) is fixedly connected to the output end at the lower left side of the water pump (11). The bottle body positioning mechanism (4) comprises a fixed hollow bracket (41), the rear end of the fixed hollow bracket (41) penetrates to the rear side of the cleaning box (1) and is fixedly connected to the output end of the fixed long tube (111), the front end of the fixed hollow bracket (41) is penetrated and fixedly connected to a base box (42), and the top of the base box (42) is penetrated and fixedly connected to a bottle body placement box (43).
2. The cleaning device for thawing umbilical cord blood hematopoietic stem cells according to claim 1, characterized in that: A plurality of rotating motors (431) are fixedly installed in a circular array at an eccentric position at the bottom of the inner wall of the bottle body placement box (43); the output shafts of the plurality of rotating motors (431) all penetrate the top of the bottle body placement box (43) and are fixedly installed with rotating rods (432); cleaning brushes (433) are fixedly installed on opposite sides of the outer walls of the plurality of rotating rods (432); a sponge head (434) is fixedly installed at the top of the rotating rod (432); water spray heads (435) are arranged on the front and rear sides of the plurality of rotating rods (432), and the water spray heads (435) are all fixedly connected to the top of the bottle body placement box (43).
3. The cleaning device for thawing umbilical cord blood hematopoietic stem cells according to claim 2, characterized in that: The flushing and clamping mechanism (5) comprises an electric push rod (51), the electric push rod (51) is fixedly mounted at the center of the top of the inner wall of the cleaning box (1), a clamping hollow disk (52) is fixedly mounted at the bottom output end of the electric push rod (51), a water delivery hose (112) is fixedly connected to the upper left output end of the water pump (11), the output end of the water delivery hose (112) penetrates the inner cavity of the cleaning box (1) and is fixedly connected to the top of the clamping hollow disk (52), a plurality of extrusion cylinders (53) are fixedly connected in a circular array at the eccentric bottom of the clamping hollow disk (52), the plurality of extrusion cylinders (53) are respectively located above a plurality of rotating rods (432), and a flushing port (54) is fixedly connected to the bottom of the plurality of extrusion cylinders (53).
4. The cleaning device for thawing umbilical cord blood hematopoietic stem cells according to claim 1, characterized in that: An inclined guide plate (61) is fixedly mounted on the right side of the inner wall of the wastewater tank (6), a sewage pipe (62) is fixedly connected to the left side of the bottom of the wastewater tank (6), and the top end of the sewage pipe (62) is connected to the left side of the inner cavity of the wastewater tank (6).
