Nucleic acid extractor for extracting nucleic acid

Abstract

The utility model discloses a nucleic acid extractor for extracting nucleic acid, which relates to the technical field of nucleic acid extraction and comprises a box body, a placing table is arranged at the inner bottom of the box body, a rod sleeve frame and a magnetic rod table are sequentially arranged above the placing table, a plurality of groups of magnetic rods are arranged below the magnetic rod table, and a plurality of groups of rod sleeve grooves are formed in the side surface of the rod sleeve frame. A gap allowing a magnetic bar to penetrate through is formed above each group of bar sleeve grooves, a mounting groove is formed in one side of the tail end of each bar sleeve groove, a through groove is formed in one inner side of each mounting groove, the mounting grooves are communicated with the bar sleeve grooves through the through grooves, and a mounting assembly is movably arranged in each mounting groove; according to the nucleic acid extractor for extracting the nucleic acid, the mounting assembly is arranged, the magnetic bar sleeve is in contact with the jacking rod and drives the jacking rod to move when being mounted, so that the hanging needle reaches the hanging end in the sliding groove, the magnetic bar sleeve is pushed again to finish dismounting, the dismounting efficiency of the magnetic bar sleeve is improved, the mounting stability of the magnetic bar sleeve is improved, and the practicability is high. And the problem of sample scattering and pollution caused by non-uniform force during disassembly and assembly is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of nucleic acid extraction, in particular to a nucleic acid extraction instrument for extracting nucleic acid. Background Art

[0002] Nucleic acid extractors are instruments that automatically extract nucleic acid from samples using matching nucleic acid extraction reagents. They are widely used in disease control centers, clinical disease diagnosis, blood transfusion safety, forensic identification, environmental microbial testing, food safety testing, animal husbandry, molecular biology research, and other fields.

[0003] According to the size of the instrument model, automatic liquid workstations and small automatic nucleic acid extractors are divided. Small automated instruments achieve the purpose of automatic nucleic acid extraction through the particularity of the operating structure and can be used in any laboratory. During the use of the small automatic nucleic acid extractor, the magnetic rod sleeve needs to be inserted into the rod sleeve rack, and then the reagent kit is placed on the placement table, and then the equipment is started to perform a series of tasks such as sample lysis, cleaning, elution, and recovery of magnetic beads. Now, when the magnetic rod sleeve is inserted into the rod sleeve rack, it is usually fixed by the friction between the magnetic rod sleeve and the rod sleeve rack, which is more laborious during installation and removal. At the same time, it is possible that the sample will leak due to inertia when it takes a lot of effort to dismantle it, causing pollution and safety hazards to the operator. At the same time, there is also the possibility that the installation is not firm and it will shake during the operation of the equipment, causing sample splashing and contamination. Utility Model Content

[0004] In view of the problem that the existing magnetic rod sleeve and rod sleeve frame are laborious to install and are prone to unstable installation, the utility model is proposed.

[0005] Therefore, the utility model aims to provide a nucleic acid extractor for extracting nucleic acid, and its purpose is to achieve rapid disassembly and assembly of the magnetic rod sleeve and the rod sleeve frame, improve disassembly and assembly efficiency, and save time and labor.

[0006] In order to solve the above technical problems, the utility model provides the following technical solutions: a nucleic acid extractor for extracting nucleic acid, comprising a box body, a placing table is provided at the inner bottom of the box body, a rod sleeve rack and a magnetic rod table are provided above the placing table in sequence, a plurality of groups of magnetic rods are provided below the magnetic rod table, a plurality of groups of rod sleeve grooves are provided on the side of the rod sleeve rack, a gap for the magnetic rods to pass through is provided above each group of the rod sleeve grooves, a mounting groove is provided on one side of the end of the rod sleeve groove, a through groove is provided on one inner side of the mounting groove, the mounting groove and the rod sleeve groove are connected through the through groove, a mounting assembly is movably provided in the mounting groove, the mounting assembly comprises a tightening rod, and the tightening rod One side is provided with a moving block, one end of the tightening rod passes through the through slot, extends into the rod sleeve slot and is slidably connected in the through slot, the moving block is slidably arranged in the installation slot, one end of the moving block is provided with a first spring, the other end of the first spring is movably connected to the inner side wall of the installation slot, and the other side of the moving block is provided with a hanging pin, one end of the hanging pin is a rotating end, the rotating end is rotatably arranged in the installation slot, and the other end of the hanging pin is a moving end. The upper end surface of the moving block is provided with a sliding groove to limit the movement of the hanging pin, and the moving end is slidably connected in the sliding groove; it can be realized that when the moving block moves, the hanging pin moves in the sliding groove, thereby driving the tightening rod to move to install and disassemble the magnetic rod sleeve.

[0007] As a preferred solution of the nucleic acid extraction instrument for extracting nucleic acid described in the utility model, an inclined groove is provided on one side of the rod sleeve groove, a friction plate is movably provided below the other end of the tightening rod, the friction plate is slidably connected in the inclined groove, and the inclined groove is inclined to drive the friction plate to move up and down so that the friction plate and the magnetic rod sleeve can be ensured that when the tightening rod is in a locked state, the friction plate moves upward in the inclined groove and contacts the magnetic rod sleeve to tighten the magnetic rod sleeve.

[0008] As a preferred solution of the nucleic acid extractor for extracting nucleic acid described in the utility model, a second spring is provided on the side of one end of the hanging needle close to the tightening rod, and the second spring is movably connected between the hanging needle and the mounting groove; the second spring can ensure that the hanging needle is always biased toward the side close to the tightening rod to ensure that the hanging needle can move smoothly.

[0009] As a preferred solution of the nucleic acid extractor for extracting nucleic acid described in the utility model, the slide groove is divided into a forward end, a hanging end and a return end, and a unidirectionally movable slope is provided between the forward end and the return end; after the magnetic rod sleeve is installed in the rod sleeve rack, it is ensured that the installation and disassembly are achieved by moving the hanging needle in the slide groove.

[0010] As a preferred solution of the nucleic acid extractor for extracting nucleic acid described in the utility model, wherein: an ultraviolet lamp is provided on the inner top of the box body to achieve sterilization and disinfection inside the box body.

[0011] As a preferred solution of the nucleic acid extractor for extracting nucleic acid described in the utility model, several groups of pillars are arranged at the bottom of the box, and sound insulation sponges are arranged between the box and the pillars to reduce vibration and noise transmitted during operation inside the box.

[0012] As a preferred solution of the nucleic acid extractor for extracting nucleic acid described in the utility model, a protective door is rotatably provided in front of the box, and an observation window is provided on the protective door, so as to ensure the safe operation of the equipment and facilitate the operator to observe the internal situation.

[0013] Beneficial effects of the utility model:

[0014] 1. By setting the installation assembly, the magnetic rod sleeve contacts the top tightening rod during installation and drives the top tightening rod to move so that the hanging needle reaches the hanging end in the slide slot, and the friction plate moves upward in the inclined slot and contacts the magnetic rod sleeve to fix the magnetic rod sleeve to achieve installation of the magnetic rod sleeve. The magnetic rod sleeve can be disassembled by pushing the magnetic rod sleeve again, which improves the efficiency of disassembly and assembly of the magnetic rod sleeve, saves manpower, improves the installation stability of the magnetic rod sleeve, and avoids the problem of sample spillage and contamination due to uneven force during disassembly and assembly;

[0015] 2. By installing an ultraviolet lamp on the top of the box, the box is effectively sterilized and disinfected, reducing bacterial growth. By installing a sound insulation sponge at the bottom of the box, the vibration and noise inside the box are reduced, reducing noise pollution in the working environment. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the following briefly introduces the drawings required for the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative labor. Among them:

[0017] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0018] Figure 2 This is a schematic diagram of the rod sleeve structure of the utility model;

[0019] Figure 3 This is a schematic structural diagram of the rod sleeve frame of the utility model from another perspective;

[0020] Figure 4 For the utility model Figure 2 A schematic diagram of the enlarged structure at A in the middle;

[0021] Figure 5 For the utility model Figure 3 A schematic diagram of the enlarged structure at B in the middle;

[0022] Figure 6 It is a structural schematic diagram of the moving block and the hanging pin of the utility model.

[0023] Description of reference numerals:

[0024] 1. Box body; 2. Placing table; 3. Rod sleeve rack; 4. Magnetic rod table; 5. Magnetic rod; 6. Rod sleeve slot; 7. Mounting slot; 8. Tightening rod; 9. Moving block; 10. First spring; 11. Hanging needle; 1101. Rotating end; 1102. Moving end; 12. Slide groove; 1201. Forward end; 1202. Hanging end; 1203. Return end; 1204. Slope; 13. Friction plate; 14. Second spring; 15. Ultraviolet lamp; 16. Pillar; 17. Sound insulation sponge; 18. Protective door; 19. Observation window. DETAILED DESCRIPTION

[0025] In order to make the above-mentioned purposes, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below in conjunction with the accompanying drawings.

[0026] Reference Figure 1-6, is an embodiment of the utility model, which provides a nucleic acid extraction instrument for extracting nucleic acid, and the nucleic acid extraction instrument for extracting nucleic acid includes a box body 1, a placing table 2 is provided at the inner bottom of the box body 1, and a rod sleeve frame 3 and a magnetic rod table 4 are provided above the placing table 2 in sequence, and the rod sleeve frame 3 and the magnetic rod table 4 are slidably connected to the inner side of the box body 1, and a driving device is provided in the box body 1, and the driving device is a servo motor, and the rod sleeve frame 3 and the magnetic rod table 4 are respectively connected to the servo motor to realize the lifting and moving of the rod sleeve frame 3 and the magnetic rod table 4, and a plurality of groups of magnetic rods 5 are provided below the magnetic rod table 4, and a plurality of groups of rod sleeve grooves 6 are provided on the side of the rod sleeve frame 3, and a gap for the magnetic rod 5 to pass through is provided above each group of rod sleeve grooves 6, and a mounting groove 7 is provided on one side of the end of the rod sleeve groove 6, and a through groove is provided on one inner side of the mounting groove 7, and the mounting groove 7 and the rod sleeve groove 6 are connected through the through groove, and the mounting groove 7 is provided inside. A mounting assembly is movably provided, which includes a tightening rod 8, a moving block 9 is provided on one side of the tightening rod 8, one end of the tightening rod 8 passes through the through slot, extends into the rod sleeve slot 6 and is slidably connected in the through slot, the moving block 9 is slidably arranged in the mounting slot 7, one end of the moving block 9 is provided with a first spring 10, the other end of the first spring 10 is movably connected to the inner side wall of the mounting slot 7, and a hanging pin 11 is provided on the other side of the moving block 9, one end of the hanging pin 11 is a rotating end 1101, the rotating end 1101 is rotatably arranged in the mounting slot 7, the other end of the hanging pin 11 is a moving end 1102, and the upper end surface of the moving block 9 is provided with a slide groove 12 for limiting the movement of the hanging pin 11, and the moving end 1102 is slidably connected in the slide groove 12; it can be realized that when the moving block 9 moves, the hanging pin 11 moves in the slide groove 12, thereby driving the tightening rod 8 to move to install and disassemble the magnetic rod 5 set. An inclined groove is provided on one side of the rod sleeve groove 6, and a friction plate 13 is movably provided at the lower part of the other end of the tightening rod 8. The friction plate 13 is slidably connected in the inclined groove, and the inclined groove is inclined to drive the friction plate 13 to move up and down so that the friction plate 13 and the magnetic rod 5 are sleeved; it can ensure that when the tightening rod 8 is in a locked state, the friction plate 13 moves upward in the inclined groove and contacts with the magnetic rod 5 to tighten the magnetic rod 5.

[0027] A second spring 14 is provided on one end of the hanging pin 11 near the side of the tightening rod 8, and the second spring 14 is movably connected between the hanging pin 11 and the mounting groove 7; the second spring 14 can ensure that the hanging pin 11 is always biased toward the side near the tightening rod 8 to ensure that the hanging pin 11 can move smoothly. The slide 12 is divided into a forward end 1201, a hanging end 1202 and a return end 1203, and a unidirectionally movable slope 1204 is provided between the forward end 1201 and the return end 1203; ensure that the magnetic rod 5 is installed in the rod sleeve frame 3 and the hanging pin 11 is moved in the slide 12 to achieve installation and removal.

[0028] An ultraviolet lamp 15 is provided at the top of the box 1 to sterilize the inside of the box 1. Several groups of pillars 16 are provided at the bottom of the box 1, and sound insulation sponges 17 are provided between the box 1 and the pillars 16 to reduce the vibration and noise transmitted during the operation inside the box 1. A protective door 18 is provided at the front of the box 1, and an observation window 19 is provided on the protective door 18 to ensure the safe operation of the equipment and facilitate the operator to observe the internal situation.

[0029] During use, first insert the magnetic rod 5 into the rod sleeve groove 6, the magnetic rod 5 is in contact with the tightening rod 8, and the tightening rod 8 is continued to be pushed. The magnetic rod 5 will push the tightening rod 8 to move and drive the moving block 9 to move, and the hanging needle 11 will move in the slide groove 12. Due to the restriction of the slope 1204, the hanging needle 11 will want to move to the forward end 1201. At this time, the hanging needle 11 will move along the slide groove 12 to the side close to the tightening rod 8 due to the traction force of the second spring 14 and then reach the hanging end 1202. At this time, the friction plate 13 at the bottom of the other side of the tightening rod 8 will move upward in the inclined groove and have friction contact with the magnetic rod 5 to tighten the magnetic rod 5. At this time, stop Push the 5 sets of magnetic bars to complete the installation, and then install the other 5 sets of magnetic bars and reagent kits in turn, and start the extraction work. After the work is completed, push the 5 sets of magnetic bars to move again, and the hanging needle 11 will move toward the return end 1203 with the movement of the moving block 9. At this time, release the 5 sets of magnetic bars, and the moving block 9 will move in the opposite direction under the pulling force of the first spring 10, driving the tightening rod 8 to move and then push the 5 sets of magnetic bars out of the rod sleeve groove 6 to complete the disassembly, and then start the ultraviolet lamp 15 for sterilization, which improves the disassembly and assembly efficiency of the 5 sets of magnetic bars, saves manpower, improves the installation stability of the 5 sets of magnetic bars, and avoids the problem of sample spillage and contamination due to uneven force during disassembly and assembly.

[0030] It should be noted that the above embodiments are only used to illustrate the technical solution of the utility model rather than to limit it. Although the utility model has been described in detail with reference to the preferred embodiments, ordinary technicians in the field should understand that the technical solution of the utility model can be modified or replaced by equivalents without departing from the spirit and scope of the technical solution of the utility model, which should be included in the scope of the claims of the utility model.

Claims

1. A nucleic acid extractor for extracting nucleic acid, Features: The invention comprises a box body (1), wherein a placing platform (2) is provided at the inner bottom of the box body (1), a rod sleeve frame (3) and a magnetic rod platform (4) are provided above the placing platform (2) in sequence, a plurality of groups of magnetic rods (5) are provided below the magnetic rod platform (4), a plurality of groups of rod sleeve grooves (6) are provided on the side of the rod sleeve frame (3), a gap for allowing the magnetic rods (5) to pass through is provided above each group of the rod sleeve grooves (6), a mounting groove (7) is provided at one end of the rod sleeve groove (6), a through groove is provided on one inner side of the mounting groove (7), the mounting groove (7) and the rod sleeve groove (6) are connected through the through groove, a mounting assembly is movably provided in the mounting groove (7), the mounting assembly comprises a tightening rod (8), a moving block (9) is provided on one side of the tightening rod (8), and the One end of the tightening rod (8) passes through the through slot and extends into the rod sleeve slot (6) and is slidably connected in the through slot; the moving block (9) is slidably arranged in the mounting slot (7); a first spring (10) is provided at one end of the moving block (9); the other end of the first spring (10) is movably connected to the inner side wall of the mounting slot (7); a hanging pin (11) is provided on the other side of the moving block (9); one end of the hanging pin (11) is a rotating end (1101); the rotating end (1101) is rotatably arranged in the mounting slot (7); the other end of the hanging pin (11) is a moving end (1102); the upper end surface of the moving block (9) is provided with a sliding groove (12) for limiting the movement of the hanging pin (11); the moving end (1102) is slidably connected in the sliding groove (12).

2. The nucleic acid extractor according to claim 1, Features: An oblique groove is provided on one side of the rod sleeve groove (6), and a friction plate (13) is movably provided below the other end of the tightening rod (8), and the friction plate (13) is slidably connected in the oblique groove.

3. The nucleic acid extractor for extracting nucleic acid according to claim 1, Features: A second spring (14) is provided on one side of one end of the hanging pin (11) close to the tightening rod (8), and the second spring (14) is movably connected between the hanging pin (11) and the mounting groove (7).

4. The nucleic acid extractor for extracting nucleic acid according to claim 1, Features: The slide groove (12) is divided into a forward end (1201), a suspension end (1202) and a return end (1203), and a unidirectionally movable slope (1204) is provided between the forward end (1201) and the return end (1203).

5. The nucleic acid extractor for extracting nucleic acid according to claim 1, Features: An ultraviolet lamp (15) is provided on the inner top of the box (1).

6. The nucleic acid extractor for extracting nucleic acid according to claim 1, Features: A plurality of groups of pillars (16) are provided at the bottom of the box body (1), and a sound insulation sponge (17) is provided between the box body (1) and the pillars (16).

7. The nucleic acid extractor for extracting nucleic acid according to claim 1, Features: A protective door (18) is rotatably provided in front of the box body (1), and an observation window (19) is provided on the protective door (18).

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