High-throughput tissue grinding equipment

Abstract

The utility model discloses high-flux tissue grinding equipment which comprises a device shell, an operation panel is arranged at the front end of the device shell, a device sealing cover is arranged at the rear end of the device shell, and a vibration seat is arranged at the upper end of the device shell. Compared with the prior art, the device has the advantages that the inserting block A, the inserting block B and the inserting block C are movably connected to the two sides of the four ends of the vibration base respectively, and the inserting holes A, the inserting holes B and the inserting holes C are formed in the upper ends of the inserting block A, the inserting block B and the inserting block C, so that a worker can place reagents of different sizes conveniently, and the applicability of the device is improved; and if the inserting block A, the inserting block B and the inserting block C need to be replaced or damaged, the sliding block slides, in the sliding process of the sliding block, the limiting column at the upper end of the sliding block is separated from the limiting grooves in the bottom ends of the inserting block A, the inserting block B and the inserting block C, and then a worker can conveniently disassemble, assemble and replace the inserting block A, the inserting block B and the inserting block C.

Description

Technical Field

[0001] The utility model relates to the technical field of grinding equipment, in particular to a high-throughput tissue grinding equipment. Background Art

[0002] The tissue grinder is a truly multifunctional and efficient laboratory sample preparation instrument. It is a new product specially launched for "small amount of samples". It realizes sample crushing, mixing, homogenization and cell disruption by oscillating tungsten carbide balls or stainless steel beads back and forth in the sample tube. It can quickly crush and homogenize hard, soft, elastic and other samples, meeting the requirements of physical and chemical analysis laboratories. It is equipped with grinding jars of different volumes and materials, and can perform dry grinding, wet grinding and frozen grinding, as well as cell disruption and DNA / RNA extraction.

[0003] Among them, the existing patent CN202221948563.X is a high-throughput tissue grinder, which is equipped with a placement plate. Multiple test tube bodies containing tissue samples can be placed on the placement plate at the same time. The motor generates a driving force, causing the placement plate to move up and down to form vibration, thereby causing multiple test tube bodies to vibrate. The samples in the test tube bodies collide with the grinding balls, and the grinding shear force and impact force generated break the tissue, thereby effectively separating and extracting the original DNA and RNA.

[0004] However, the existing test tubes are of different sizes, and most tissue grinder placement plates can only accommodate one test tube size. They cannot simultaneously and quickly crush and homogenize multiple different reagents, and their applicability is low. Therefore, they do not meet existing needs. We have proposed a high-throughput tissue grinding device. Utility Model Content

[0005] The purpose of the utility model is to provide a high-throughput tissue grinding device to solve the problems mentioned in the above background technology, that the existing test tube bodies are of different sizes, and most of the tissue grinder placement plates can only be used for one test tube size, and multiple different reagents cannot be simultaneously and quickly crushed and homogenized, and the applicability is low.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a high-throughput tissue grinding device, comprising a device housing, a front end of the device housing is provided with an operation panel, a rear end of the device housing is provided with a device sealing cover, an upper end of the device housing is provided with a vibration seat, a reciprocating screw is provided at the center position of the upper end of the vibration seat, a limit sleeve is provided at the upper end of the reciprocating screw, the bottom end of the reciprocating screw passes through the vibration seat and extends to the inner side of the device housing, the two sides of the four ends of the vibration seat are respectively movably connected with plug blocks A, plug blocks B and plug blocks C, and the bottom ends of both sides of the vibration seat are provided with sliders.

[0007] Preferably, one end of the plug block A, the plug block B and the plug block C is located on the inner side of the vibration seat and a slot is provided, and the plug block A, the plug block B and the plug block C are plugged into the inner side of the slot.

[0008] Preferably, two plug blocks C are provided, and the upper end surfaces of the plug blocks A, B and C are provided with holes A, B and C respectively, the diameter of the hole C is twice that of the hole B, and the diameter of the hole B is twice that of the hole A.

[0009] Preferably, one end of the slider extends to the inner side of the vibration seat, the upper end of the slider is located on the inner side of the vibration seat and a limit column is provided, and the bottom ends of the plug A, plug B and plug C above the limit column are all provided with limit grooves, and the limit column passes through the vibration seat and the slot and extends to the inner side of the limit groove.

[0010] Preferably, a slide groove is provided at the bottom end of the slider on the inner side of the vibration seat, a spring is provided on the inner side of the slide groove, the slide groove and the spring are fixedly connected by bolts, and the slider is movably connected to the vibration seat through the spring.

[0011] Preferably, a servo motor is provided at the bottom end of the reciprocating screw rod, which is located on the inner side of the device housing, and the servo motor is electrically connected to the operation panel.

[0012] Preferably, a hinge is provided below the rear side of the device sealing cover at the rear end of the device housing, and the device housing and the device sealing cover are connected via the hinge.

[0013] Compared with the prior art, the beneficial effects of the utility model are:

[0014] The utility model is provided with plug blocks A, plug blocks B and plug blocks C movably connected to both sides of the four ends of the vibration seat respectively, and the sockets A, socket B and socket C on the upper ends of the plug blocks A, plug blocks B and plug blocks C can facilitate the staff to place reagents of different sizes, thereby improving the applicability of the device. After the grinding is completed, if the plug blocks A, plug blocks B and plug blocks C need to be replaced or damaged, the slider can be slid, and during the sliding process, the limit column on the upper end of the slider is disengaged from the limit groove at the bottom end of the plug blocks A, plug blocks B and plug blocks C, thereby facilitating the staff to disassemble and replace the plug blocks A, plug blocks B and plug blocks C. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0016] Figure 2 This is a schematic diagram of the structure of the vibration seat of the utility model;

[0017] Figure 3 It is a schematic diagram of the top view of the vibration seat of the utility model;

[0018] Figure 4 It is a schematic diagram of the internal structure of the slider and the vibration seat of the utility model.

[0019] In the figure: 1. device housing; 2. device sealing cover; 3. operation panel; 4. slider; 401. limit column; 5. vibration seat; 501. slot; 6. reciprocating screw rod; 7. limit sleeve; 8. plug block A; 9. plug block B; 10. plug block C; 11. socket A; 12. socket B; 13. socket C; 14. limit groove. DETAILED DESCRIPTION

[0020] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0021] like Figure 1 As shown, an embodiment of the utility model is: a high-throughput tissue grinding device, comprising a device housing 1, an operation panel 3 is provided at the front end of the device housing 1, a device sealing cover 2 is provided at the rear end of the device housing 1, a hinge is provided below the rear side of the device sealing cover 2 at the rear end of the device housing 1, the device housing 1 and the device sealing cover 2 are connected by a hinge, a vibration seat 5 is provided at the upper end of the device housing 1, a reciprocating screw rod 6 is provided at the center position of the upper end of the vibration seat 5, a limiting sleeve 7 is provided at the upper end of the reciprocating screw rod 6, the bottom end of the reciprocating screw rod 6 passes through the vibration seat 5 and extends to the inner side of the device housing 1, the bottom end of the reciprocating screw rod 6 is located on the inner side of the device housing 1 and is provided with a servo motor, the servo motor is electrically connected to the operation panel 3, and plug blocks are movably connected to both sides of the four ends of the vibration seat 5 A8, plug block B9 and plug block C10, sliders 4 are provided at the bottom ends of both sides of the vibration seat 5, and the plug blocks A8, plug block B9 and plug block C10 are movably connected to the two sides of the four ends of the vibration seat 5 as a whole, and the sockets A11, socket B12 and socket C13 on the upper ends of the plug blocks A8, plug block B9 and plug block C10 can facilitate the staff to place reagents of different sizes, thereby improving the applicability of the device. After the grinding is completed, if the plug blocks A8, plug block B9 and plug block C10 need to be replaced or damaged, the slider 4 is slid. During the sliding process of the slider 4, the limit column 401 at the upper end of the slider 4 is disengaged from the limit groove 14 at the bottom end of the plug blocks A8, plug block B9 and plug block C10, thereby facilitating the staff to disassemble and replace the plug blocks A8, plug block B9 and plug block C10.

[0022] As the preferred technical solution of this embodiment, Figure 2 and Figure 3As shown, one end of the plug block A8, the plug block B9 and the plug block C10 is located on the inner side of the vibration seat 5 and is provided with a slot 501. The plug blocks A8, the plug block B9 and the plug block C10 are plugged into the inner side of the slot 501. There are two plug blocks C10. The upper end surfaces of the plug blocks A8, the plug block B9 and the plug block C10 are respectively provided with a socket A11, a socket B12 and a socket C13. The diameter of the socket C13 is one times that of the socket B12, and the diameter of the socket B12 is one times that of the socket A11, so that the plug blocks A8, the plug block B9 and the plug block C10 are conveniently connected to the vibration seat 5 through the slot 501. The sockets A11, the socket B12 and the socket C13 on the upper ends of the plug blocks A8, the plug block B9 and the plug block C10 can facilitate the staff to place reagents of different sizes, thereby improving the applicability of the device.

[0023] As the preferred technical solution of this embodiment, Figure 4 As shown, one end of the slider 4 extends to the inner side of the vibration seat 5, the upper end of the slider 4 is located on the inner side of the vibration seat 5 and is provided with a limiting column 401, the upper end of the limiting column 401 is located on the inner side of the vibration seat 5, and the bottom ends of the plug A8, the plug B9 and the plug C10 are all provided with a limiting groove 14, the limiting column 401 penetrates the vibration seat 5 and the slot 501 and extends to the inner side of the limiting groove 14, one end of the slider 4 extends to the inner side of the vibration seat 5, the upper end of the slider 4 is located on the inner side of the vibration seat 5 and is provided with a limiting column 401, the limiting column 40 1, the bottom ends of the plug blocks A8, B9 and C10 are all provided with limiting grooves 14, and the limiting posts 401 penetrate the vibration seat 5 and the slot 501 and extend to the inner side of the limiting grooves 14. Then, when the plug blocks A8, B9 and C10 are inserted into the inner side of the slot 501, the slider 4 is clamped into the limiting grooves 14 on the bottom surfaces of the plug blocks A8, B9 and C10 through the spring, so that the plug blocks A8, B9 and C10 are fixed by the slider 4.

[0024] In summary, when the grinding device is used, first check whether each component is intact. After the inspection is completed, the two sides of the four ends of the vibration seat 5 are movably connected with the plug block A8, the plug block B9 and the plug block C10, and the plug holes A11, the plug hole B12 and the plug hole C13 on the upper ends of the plug blocks A8, the plug block B9 and the plug block C10 can facilitate the staff to place reagents of different sizes, improve the applicability of the device, put the grinding ball into the reagent to be ground, and then put the reagent into the plug blocks A8, the plug block B9 and the plug block C10 respectively. In the process, the power is turned on and the equipment is started, so that the vibration seat 5 is lifted and lowered inside the device through the reciprocating screw 6, so as to grind the inside of the reagent. After the grinding is completed, if the plug-in block A8, the plug-in block B9 and the plug-in block C10 need to be replaced or damaged, the slider 4 is slid. During the sliding process of the slider 4, the limit column 401 at the upper end of the slider 4 is disengaged from the limit groove 14 at the bottom end of the plug-in block A8, the plug-in block B9 and the plug-in block C10, thereby facilitating the staff to disassemble and replace the plug-in block A8, the plug-in block B9 and the plug-in block C10.

[0025] It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be regarded as exemplary and non-restrictive from any point of view, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.

Claims

1. A high-throughput tissue grinding device, comprising a device housing (1), characterized in that: The front end of the device housing (1) is provided with an operation panel (3), the rear end of the device housing (1) is provided with a device sealing cover (2), the upper end of the device housing (1) is provided with a vibration seat (5), a reciprocating screw rod (6) is provided at the center position of the upper end of the vibration seat (5), the upper end of the reciprocating screw rod (6) is provided with a limit sleeve (7), the bottom end of the reciprocating screw rod (6) penetrates the vibration seat (5) and extends to the inner side of the device housing (1), the two sides of the four ends of the vibration seat (5) are respectively movably connected with an insert block A (8), an insert block B (9) and an insert block C (10), and the bottom ends of both sides of the vibration seat (5) are provided with sliders (4).

2. A high-throughput tissue grinding device according to claim 1, characterized in that: One end of the plug block A (8), the plug block B (9) and the plug block C (10) is located on the inner side of the vibration seat (5) and is provided with a slot (501), and the plug block A (8), the plug block B (9) and the plug block C (10) are plugged into the inner side of the slot (501).

3. A high-throughput tissue grinding device according to claim 1, characterized in that: Two plug blocks C (10) are provided, and the upper end surfaces of the plug blocks A (8), B (9) and C (10) are respectively provided with a plug hole A (11), a plug hole B (12) and a plug hole C (13), the diameter of the plug hole C (13) is twice that of the plug hole B (12), and the diameter of the plug hole B (12) is twice that of the plug hole A (11).

4. A high-throughput tissue grinding device according to claim 1, characterized in that: One end of the slider (4) extends to the inner side of the vibration seat (5); the upper end of the slider (4) is located on the inner side of the vibration seat (5) and is provided with a limiting column (401); the upper end of the limiting column (401) is located on the inner side of the vibration seat (5) and is provided with a limiting groove (14); the bottom ends of the plug A (8), the plug B (9) and the plug C (10) are all provided with a limiting groove (14); the limiting column (401) penetrates the vibration seat (5) and the slot (501) and extends to the inner side of the limiting groove (14).

5. A high-throughput tissue grinding device according to claim 1, characterized in that: The bottom end of the slider (4) is located inside the vibration seat (5) and is provided with a slide groove, the inside of the slide groove is provided with a spring, the slide groove and the spring are fixedly connected by bolts, and the slider (4) is movably connected to the vibration seat (5) via the spring.

6. A high-throughput tissue grinding device according to claim 1, characterized in that: The bottom end of the reciprocating screw rod (6) is located on the inner side of the device housing (1) and is provided with a servo motor, and the servo motor is electrically connected to the operation panel (3).

7. A high-throughput tissue grinding device according to claim 1, characterized in that: A hinge is provided below the rear side of the device sealing cover (2) at the rear end of the device housing (1), and the device housing (1) and the device sealing cover (2) are connected via the hinge.

Images