Uniform cell spreader

By introducing a mixing mechanism and ball design into the cell coating device, the problem of uneven cell accumulation and dispersion in the sample solution is solved, and uniform coating of cells and smooth movement of the coating head is achieved.

CN222212396UActive Publication Date: 2024-12-20SHANGHAI ENZYMIC BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202420013086.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-01-02
Publication Date
2024-12-20
Estimated Expiration
2034-01-02

AI Technical Summary

Technical Problem

When used, existing cell coating devices cannot mix the sample solution evenly before coating, resulting in uneven cell accumulation and dispersion of cells.

Method used

A cell uniform coating device including a storage tube, a mixing mechanism and a coating head is designed. The drive shaft and mixing blade are driven by a motor to stir the sample solution evenly disperse, and a ball is provided at the bottom of the coating head to lower the Friction force improves coating smoothness.

Benefits of technology

The sample solution is uniformly mixed before coating, avoiding cell accumulation, ensuring uniform dispersion of cells during coating, and improving the smooth movement of the coating head.

✦ Generated by Eureka AI based on patent content.

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  • Figure CN222212396U_ABST
    Figure CN222212396U_ABST
Patent Text Reader

Abstract

The utility model discloses a cell uniform coater, including storage tube, mixing mechanism and coating head, the mixing mechanism is composed of motor casing, drive motor, transmission shaft and mixing blade, the motor casing threaded connection is in the storage tube top, drive motor is installed in the motor casing, transmission shaft is provided in the storage tube, and the mixing blade is in the storage tube. The top end of the transmission shaft extends into the motor shell and is in transmission connection with the driving motor, the mixing blades are fixedly connected to the surface of the transmission shaft, a delivery pipe is fixedly connected to the interior of the storage pipe, the bottom end of the delivery pipe extends to the position below the bottom of the storage pipe, and the coating head is in threaded connection to the bottom end of the delivery pipe. According to the utility model, the uniform mixing mechanism is arranged above the storage tube, and a sample solution can be uniformly mixed by virtue of the uniform mixing mechanism before coating, so that cells are uniformly dispersed in the sample solution, the cells in the sample solution are prevented from being dispersed and accumulated, and the cells can be uniformly dispersed during coating.
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Description

Technical Field

[0001] The utility model relates to the technical field of cell detection, in particular to a cell uniform coating device. Background Art

[0002] Smear is to make a thin layer of samples such as cells, tissues, body fluids and evenly apply it on a glass slide. This method is often used for blood tests, bacteria and pathogen detection, etc. The prepared smear needs to be stained and observed under a microscope. The main purpose of the smear is to observe the cell morphology, chromatin and organelles in the sample and the presence of pathogens. Smear examination is a commonly used examination method in clinical practice. It mainly collects tissue from the lesion site for smear. The smear examination is relatively simple to operate and the examination site is relatively wide, including nasal secretion smear examination, cervical cytology smear examination, sputum cytology smear examination, blood smear examination, fungal smear examination, etc. Smear examination can detect cell abnormalities early, can screen various diseases, and has high diagnostic value. When making a cell smear, a coating device is needed to apply the cells to a glass slide.

[0003] When some existing cell coating devices are used, most of them directly drop the sample solution containing cells on the slide, and the sample solution cannot be mixed before coating. The cells in the sample solution are prone to accumulation, and the cells are prone to uneven dispersion during coating.

[0004] For example, a liquid-based thin layer cell detection smear device disclosed in the announcement number CN211927465U is provided with a base, a frame, a sliding rod, a scraper, a spring b and a guide tube. The frame slides in a slide groove on the base through a slider, and the sliding rod drives the scraper to move downward and contact the scraper surface. The guide tube is used to input the sample, and then the scraper can be used to quickly and evenly coat the sample, so that the sample is evenly coated on the glass slide. The structure is simple, the operation is convenient, and the coating effect is good.

[0005] However, when the smear device of the patent is used, the sample is directly poured into the guide tube so that it flows onto the glass slide through the guide tube. The sample solution cannot be mixed before coating. Cells in the sample solution are prone to accumulation, and the cells are prone to uneven dispersion during coating.

[0006] Therefore, it is necessary to invent a cell uniform spreader to solve the above problems. Utility Model Content

[0007] The utility model aims to provide a cell uniform coating device to solve the problem that some existing cell coating devices in the technology directly drop sample solutions containing cells on a glass slide when in use, and fail to mix the sample solutions before coating, so that cells in the sample solutions are prone to accumulation and cells are prone to uneven dispersion during coating.

[0008] In order to achieve the above-mentioned purpose, the utility model provides the following technical solutions: a cell uniform coating device, comprising a storage tube, a mixing mechanism and a coating head, the mixing mechanism consisting of a motor housing, a driving motor, a transmission shaft and a mixing blade, the motor housing is threadedly connected to the top of the storage tube, the driving motor is installed inside the motor housing, the transmission shaft is arranged inside the storage tube, the top of the transmission shaft extends to the inside of the motor housing and is transmission-connected to the driving motor, the mixing blade is fixedly connected to the surface of the transmission shaft, the storage tube is fixedly connected with a derivation tube, the bottom end of the derivation tube extends to below the bottom of the storage tube, and the coating head is threadedly connected to the bottom end of the derivation tube.

[0009] The driving motor drives the transmission shaft and the mixing blades to rotate, thereby stirring and mixing the sample solution, so that the cells are evenly dispersed in the sample solution.

[0010] Preferably, a display screen and control buttons are mounted on the surface of the motor housing, and both the display screen and the control buttons are electrically connected to the drive motor.

[0011] The speed and time of the drive motor can be controlled through the control buttons, and the current operating parameters of the drive motor can be displayed through the display screen.

[0012] Preferably, a stopcock is rotatably connected inside the storage tube, and the stopcock is arranged through the outlet tube.

[0013] The outlet tube is sealed with a stopcock.

[0014] Preferably, a through hole is opened in the middle of the plug, and the through hole is located inside the outlet tube. One end of the plug extends to the outside of the storage tube and is fixedly connected with a paddle.

[0015] The cock can be easily rotated by means of a pick, and the through hole is connected with the outlet tube, and the sample solution can be released from the storage tube.

[0016] Preferably, a coating brush is fixedly connected to one side of the bottom of the coating head, a fixing bar is fixedly connected to the other side of the bottom of the coating head, and a ball bearing is installed at the bottom of the fixing bar.

[0017] When the coating head moves, the sample solution is spread evenly on the surface of the slide with the help of a coating brush.

[0018] Preferably, the coating brush is made of medical silicone material, and the ball bearing is made of medical stainless steel material.

[0019] Both the coating brush and the ball are made of medical materials, which is beneficial to improving the safety of the device.

[0020] Preferably, the number of the balls is set to be multiple, and the multiple balls are distributed in a linear array.

[0021] The setting of the ball can reduce the friction between the coating head and the glass slide, making it easier for the coating head to move quickly.

[0022] Preferably, a gripping handle is fixedly connected to one side of the surface of the storage tube, and the mixing blades are made of medical silicone material.

[0023] When the user holds the storage tube, the user puts the palm through the holding handle to prevent accidental loosening.

[0024] In the above technical solution, the technical effects and advantages provided by the utility model are:

[0025] 1. By arranging a mixing mechanism above the storage tube, the sample solution can be mixed before coating with the help of the mixing mechanism, so that the cells are evenly dispersed in the sample solution, avoiding the dispersion and accumulation of cells in the sample solution, which is conducive to evenly dispersing the cells during coating;

[0026] 2. By setting a ball at the bottom of the coating head, the friction between the ball and the glass slide is small, which can improve the smoothness of the movement of the coating head and facilitate rapid coating on the glass slide. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0028] Figure 2 It is a structural sectional view of the utility model;

[0029] Figure 3 It is a side view of the utility model;

[0030] Figure 4 It is a structural schematic diagram of the mixing mechanism of the utility model;

[0031] Figure 5 It is a structural schematic diagram of the coating head of the utility model.

[0032] Description of reference numerals:

[0033] 1. Storage tube; 2. Coating head; 3. Motor housing; 4. Drive motor; 5. Transmission shaft; 6. Mixing blades; 7. Export pipe; 8. Display screen; 9. Control button; 10. Plug; 11. Paddle; 12. Coating brush; 13. Fixing strip; 14. Ball; 15. Holding handle. DETAILED DESCRIPTION

[0034] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below in conjunction with the accompanying drawings.

[0035] The utility model provides Figure 1-5 The cell uniform coating device shown includes a storage tube 1, a mixing mechanism and a coating head 2. The mixing mechanism consists of a motor housing 3, a drive motor 4, a transmission shaft 5 and a mixing blade 6. The motor housing 3 is threadedly connected to the top of the storage tube 1, the drive motor 4 is installed inside the motor housing 3, the transmission shaft 5 is arranged inside the storage tube 1, the top of the transmission shaft 5 extends to the inside of the motor housing 3 and is transmission-connected to the drive motor 4, the mixing blade 6 is fixedly connected to the surface of the transmission shaft 5, the storage tube 1 is fixedly connected with a derivation tube 7, the bottom end of the derivation tube 7 extends to below the bottom of the storage tube 1, and the coating head 2 is threadedly connected to the bottom end of the derivation tube 7.

[0036] In one aspect of the present embodiment, a display screen 8 and a control button 9 are installed on the surface of the motor housing 3, and the display screen 8 and the control button 9 are electrically connected to the drive motor 4. A plug 10 is rotatably connected inside the storage tube 1, and the plug 10 is arranged to penetrate the outlet tube 7. A through hole is opened in the middle of the plug 10, and the through hole is located inside the outlet tube 7. One end of the plug 10 extends to the outside of the storage tube 1 and is fixedly connected to a paddle 11. A coating brush 12 is fixedly connected to one side of the bottom of the coating head 2, and a fixing bar 13 is fixedly connected to the other side of the bottom of the coating head 2. A ball 14 is installed at the bottom of the fixing bar 13. The coating brush 12 is made of medical silicone material, and the ball 14 is made of medical stainless steel material. The number of the ball 14 is set to multiple, and the multiple balls 14 are distributed in a linear array. A gripping handle 15 is fixedly connected to one side of the surface of the storage tube 1, and the mixing blade 6 is made of medical silicone material.

[0037] Working principle of this utility model:

[0038] Refer to the instruction manual Figure 1-5 When using the utility model, firstly, the prepared sample solution with cells is injected into the storage tube 1, and then the transmission shaft 5 together with the mixing blade 6 is inserted into the solution of the storage tube 1, and then the motor housing 3 is screwed on the top of the storage tube 1 to complete the preparation before cell coating; when performing cell coating, a clean slide is placed under the coating head 2, and the ball 14 is brought into contact with the slide, and then the driving motor 4 is started by the control button 9, and the driving motor 4 drives the transmission shaft 5 and the mixing blade 6 to rotate, and with the help of the mixing blade 6 The sample solution is stirred and mixed, and the driving motor 4 is controlled to operate at a low speed to avoid damage to the cells. Then, the stopcock 10 is rotated by the paddle 11 so that the through hole on the stopcock 10 remains coaxial with the outlet tube 7. At this time, the sample solution can pass through the through hole into the outlet tube 7 and flow into the coating head 2. Finally, the sample solution falls on the surface of the glass slide. The storage tube 1 is held by hand to drive the coating head 2 to move on the surface of the glass slide. The ball 14 can improve the smoothness of the movement of the coating head 2, and the coating brush 12 can spread the sample solution on the surface of the glass slide.

Claims

1. A cell uniform coating device, comprising a storage tube (1), a mixing mechanism and a coating head (2), characterized in that: The mixing mechanism is composed of a motor housing (3), a driving motor (4), a transmission shaft (5) and a mixing blade (6); the motor housing (3) is threadedly connected to the top end of the storage tube (1); the driving motor (4) is installed inside the motor housing (3); the transmission shaft (5) is arranged inside the storage tube (1); the top end of the transmission shaft (5) extends into the motor housing (3) and is transmission-connected to the driving motor (4); the mixing blade (6) is fixedly connected to the surface of the transmission shaft (5); a guide tube (7) is fixedly connected inside the storage tube (1); the bottom end of the guide tube (7) extends below the bottom of the storage tube (1); and the coating head (2) is threadedly connected to the bottom end of the guide tube (7).

2. A cell uniform spreader according to claim 1, characterized in that: A display screen (8) and a control button (9) are mounted on the surface of the motor housing (3); the display screen (8) and the control button (9) are both electrically connected to the drive motor (4).

3. A cell uniform spreader according to claim 1, characterized in that: A stopcock (10) is rotatably connected inside the storage tube (1), and the stopcock (10) is arranged to penetrate the outlet tube (7).

4. A cell uniform spreader according to claim 3, characterized in that: A through hole is provided in the middle of the cock (10), and the through hole is located inside the outlet tube (7). One end of the cock (10) extends to the outside of the storage tube (1) and is fixedly connected to a paddle (11).

5. A cell uniform spreader according to claim 1, characterized in that: A coating brush (12) is fixedly connected to one side of the bottom of the coating head (2), a fixing bar (13) is fixedly connected to the other side of the bottom of the coating head (2), and a ball bearing (14) is installed at the bottom of the fixing bar (13).

6. A cell uniform spreader according to claim 5, characterized in that: The coating brush (12) is made of medical silicone material, and the rolling ball (14) is made of medical stainless steel material.

7. A cell uniform spreader according to claim 5, characterized in that: The number of the balls (14) is set to be multiple, and the multiple balls (14) are distributed in a linear array.

8. A cell uniform spreader according to claim 1, characterized in that: A holding handle (15) is fixedly connected to one side of the surface of the storage tube (1), and the mixing blade (6) is made of medical silicone material.

Citation Information

Patent Citations

  • Smear device for detecting liquid-based thin-layer cells

    CN211927465U