Complex mixed polymorphic sample injection device and mass spectrum detection equipment

Abstract

The utility model discloses a complex mixed polymorphic sample injection device and mass spectrum detection equipment, and the complex mixed polymorphic sample injection device comprises a sample injection port used for receiving a sample to be detected; the wavelength-adjustable infrared transmitter and the infrared receiver are arranged in the sample inlet, the infrared transmitter is used for generating infrared light with different wavelengths, and the infrared receiver is used for receiving an infrared light signal reflected or transmitted by the sample; the control unit is connected with the infrared emitter and the infrared receiver and is used for controlling the infrared emitter to emit infrared light with a specific wavelength and judging the polarity of the sample according to a signal received by the infrared receiver; the solvent configuration module is electrically connected with the control unit and is used for configuring a solvent with corresponding polarity according to the sample polarity judged by the control unit; the sample conveying module is used for mixing the solvent prepared by the solvent preparation module with a sample; the method has the advantages that the sample polarity can be automatically identified, the corresponding solvent can be rapidly prepared, and the sample pretreatment process is simplified.

Description

Technical Field

[0001] The utility model relates to the technical field of element analysis, in particular to a complex mixed multi-form sample injection device and mass spectrometry detection equipment. Background Art

[0002] Mass spectrometry detection and analysis technology has become an indispensable tool in the field of analytical chemistry because it can provide molecular ion peak information of unknown substances in a short time, and combined with secondary ion fragment peak data, determine the composition of substances by comparing standard mass spectra or databases. The core of this technology is to convert samples into ions with specific charge-to-mass ratios, and then use mass analyzers to identify these ions, thereby revealing the chemical properties of samples. With the development of mass spectrometry technology, a variety of ionization technologies have emerged, including EI (electron impact) ion source, ESI (electrospray) ion source, MALDI (matrix-assisted laser desorption / ionization) ion source, etc. Each technology has its applicable sample type. For example, ESI is suitable for processing liquid samples, while EI is more suitable for gas samples. However, when faced with multi-morphological samples, especially solid unknowns, these traditional ionization technologies show obvious limitations.

[0003] Existing mass spectrometry techniques encounter multiple obstacles when dealing with solid unknowns. On the one hand, since the solubility and volatility of solid samples are unknown, selecting appropriate solvents or treatment methods often requires repeated experiments, which not only increases experimental time and cost, but may also lead to sample loss or analysis result deviation due to improper solvent selection. On the other hand, although multi-ion source technology can improve the adaptability to samples of different forms, it also brings new problems such as large equipment size, high cost, complex operation and inconvenient maintenance. Especially when using TD (thermal desorption) technology to process solid samples, due to incomplete thermal desorption of the sample, it is easy to cause internal contamination of the ion source, affecting the accuracy and reliability of subsequent analysis. In addition, the operating temperature of TD technology is relatively high, which brings safety hazards to users.

[0004] In order to meet the needs of rapid on-site detection, especially in the fields of environmental monitoring and public safety, there is an urgent need for a new type of sample injection device and mass spectrometry detection equipment that can not only efficiently process multi-form samples, but also simplify the sample pretreatment process, reduce the difficulty of operation and improve the portability of the equipment. Current technical solutions have obvious shortcomings in these aspects. For example, although the composite ion source enhances the compatibility with different sample types, its complex structural design and high cost limit its wide application; and the traditional single ion source technology is unable to cope with complex samples. Therefore, exploring and developing innovative technical solutions to overcome the shortcomings of existing technologies is the key to promoting the advancement of mass spectrometry technology. Utility Model Content

[0005] One of the purposes of the utility model is to provide a complex mixed multi-form sample injection device, which can automatically identify the polarity of the sample and quickly configure the corresponding solvent, thereby simplifying the sample pre-treatment process.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a complex mixed multi-form sample injection device, comprising:

[0007] A sample inlet, used for receiving a sample to be tested;

[0008] An infrared transmitter and an infrared receiver with adjustable wavelength built into the injection port, wherein the infrared transmitter is used to generate infrared light of different wavelengths, and the infrared receiver is used to receive infrared light signals reflected or transmitted by the sample;

[0009] A control unit, connected to the infrared transmitter and the infrared receiver, for controlling the infrared transmitter to emit infrared light of a specific wavelength and determining the polarity of the sample according to the signal received by the infrared receiver;

[0010] A solvent configuration module, electrically connected to the control unit, and configured to configure a solvent of corresponding polarity according to the sample polarity determined by the control unit;

[0011] The sample delivery module is used to mix the solvent configured by the solvent configuration module with the sample and to deliver the processed sample to an analysis and detection instrument.

[0012] Preferably, a sample chamber is provided at the sample inlet, an oscillator is provided at the bottom of the sample chamber, the oscillator is used to promote mixing of the sample and the solvent, and a waste liquid chamber is also provided on one side of the sample chamber for collecting treated waste liquid.

[0013] Preferably, the solvent configuration module comprises:

[0014] Two solvent storage units, respectively used for storing solvents of different polarities;

[0015] A proportional valve connected to the outlet ends of the two solvent storage units, for adjusting the mixing amount of different solvents according to a preset ratio;

[0016] A solenoid valve, arranged at the outlet end of the proportional valve, for controlling the on-off of the mixed solvent;

[0017] The sampling probe is arranged at the outlet end of the electromagnetic valve and is used for injecting a mixed solvent into the sample chamber or extracting a processed sample.

[0018] Preferably, the sample delivery module includes a syringe, a plunger pump and a two-position three-way solenoid valve, one end of the syringe is connected to the plunger pump, and the other end is connected to the two-position three-way solenoid valve, one interface of the two-position three-way solenoid valve is connected to the ion source system, and the other interface is connected to the solenoid valve, and the plunger pump is used to control the extraction and injection actions of the syringe to achieve quantitative delivery of the sample.

[0019] Preferably, the ion source system comprises,

[0020] An electrospray device, used for atomizing the mixed sample, wherein the electrospray device is connected to an interface of the two-position three-way solenoid valve;

[0021] The ion inlet is arranged at the outlet end of the electrospray device and is used to guide the atomized sample into the analysis and detection instrument.

[0022] Preferably, the electrospray device comprises,

[0023] A spray needle connected to an interface of the two-position three-way solenoid valve, with a micro hole at the end thereof;

[0024] A coaxial sleeve, disposed around the spray needle, for introducing atomizing gas;

[0025] A heating device, used for heating the spray needle;

[0026] A high voltage power supply is electrically connected to the spray needle.

[0027] Preferably, the control unit comprises,

[0028] A signal processing module, electrically connected to the infrared receiver, and configured to process a signal received by the infrared receiver;

[0029] A polarity determination module, electrically connected to the signal processing module, for determining the polarity characteristics of the sample according to the processed signal;

[0030] A solvent ratio module, electrically connected to the polarity judgment module, for calculating the optimal ratio of the required solvent according to the polarity characteristics of the sample;

[0031] The control execution module is electrically connected to the solvent configuration module and is used to send a ratio control instruction to the solvent configuration module.

[0032] The second purpose of the utility model is to provide a mass spectrometry detection device, including a complex mixed multi-form sample injection device.

[0033] Compared with the prior art, the utility model has the advantages of simplifying the sample pretreatment process, improving the analysis efficiency and the portability of the equipment. The core is that an adjustable wavelength infrared transmitter and an infrared receiver are integrated in the injection port. The infrared transmitter can generate infrared light of different wavelengths. When the infrared light irradiates the injected sample, the sample will reflect or transmit. The infrared receiver can accurately measure the change of the infrared light signal after passing through the sample. In this way, the control unit can obtain the infrared spectrum information of the sample. In addition, the control unit is connected to the infrared transmitter and the receiver, and can intelligently control the emission of infrared light of a specific wavelength, and compare the signal received by the receiver with the data stored in the pre-stored database to determine the polarity characteristics of the sample. Once the sample polarity is identified, the solvent configuration module will automatically configure the optimal solvent of the corresponding polarity. The sample delivery module will fully mix the configured solvent with the original sample to form a pre-treated homogeneous solution, and then deliver it to the analysis and detection instrument.

[0034] Compared with the traditional method, this design has the following outstanding advantages:

[0035] 1. High degree of automation, no need for manual judgment and solvent configuration, greatly simplifying the complex sample pretreatment process;

[0036] 2. Accurate solvent selection avoids sample loss and analysis deviation caused by improper solvent selection;

[0037] 3. It can efficiently process complex mixed multi-morphological samples without having to make a judgment on the sample morphology in advance;

[0038] 4. The overall integrated compact design is small and easy to carry, suitable for on-site rapid detection applications. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are merely embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying any creative work.

[0040] Figure 1 It is a structural block diagram of the utility model;

[0041] Figure 2 It is a structural block diagram of the control unit in the utility model;

[0042] In the figure, 1. injection port; 2. infrared transmitter; 3. infrared receiver; 4. control unit; 5. solvent configuration module; 6. sample delivery module; 7. sample chamber; 8. oscillator; 9. waste liquid chamber; 10. solvent storage unit; 11. proportional valve; 12. solenoid valve; 13. injection probe; 14. syringe; 15. plunger pump; 16. two-position three-way solenoid valve; 17. ion source system; 18. electrospray device; 19. ion inlet; 20. signal processing module; 21. polarity judgment module; 22. solvent ratio module; 23. control execution module. DETAILED DESCRIPTION

[0043] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0044] Embodiment 1: Figure 1-Figure 2 As shown, a complex mixed multi-form sample injection device comprises:

[0045] Inlet 1, used for receiving the sample to be tested;

[0046] An infrared transmitter 2 and an infrared receiver 3 with adjustable wavelength are built into the sample inlet 1, wherein the infrared transmitter 2 is used to generate infrared light of different wavelengths, and the infrared receiver 3 is used to receive infrared light signals reflected or transmitted by the sample;

[0047] A control unit 4 is connected to the infrared transmitter 2 and the infrared receiver 3, and is used to control the infrared transmitter 2 to emit infrared light of a specific wavelength, and to determine the polarity of the sample according to the signal received by the infrared receiver 3;

[0048] The solvent configuration module 5 is electrically connected to the control unit 4 and is used to configure a solvent of corresponding polarity according to the sample polarity determined by the control unit 4;

[0049] The sample delivery module 6 is used to mix the solvent configured by the solvent configuration module 5 with the sample, and to deliver the processed sample to an analysis and detection instrument.

[0050] The complex mixed multi-morphological sample mass spectrometry injection and detection system integrates infrared detection technology and mass spectrometry technology, realizing the intelligent and efficient sample analysis process. The core of the system lies in a built-in infrared transmitter 2 with adjustable wavelength and an infrared receiver 3 in the injection port 1.

[0051] The adjustable wavelength infrared emitter 2 can generate infrared light of different wavelengths. By measuring the reflection or transmission of infrared light of different wavelengths by the sample, the infrared spectrum data of the sample can be obtained. The system provides two detection modes for this purpose:

[0052] In the rapid detection mode, the instrument will only detect several specific infrared absorption bands, quickly determine the main functional group type and polarity range of the sample, and retrieve the corresponding solvent formula from the pre-stored database to automatically configure the best solvent for sample pretreatment. This rapid detection mode greatly saves the time for sample dissolution and mass spectrometry analysis.

[0053] In laboratory mode, the instrument will complete full-wavelength scanning, collect rich functional group data, provide a reference for mass spectrometry analysis, and facilitate more in-depth structural analysis of unknown substances.

[0054] Preferably, a sample chamber 7 is provided at the sample inlet 1, an oscillator 8 is provided at the bottom of the sample chamber 7, and the oscillator 8 is used to promote mixing of the sample and the solvent. A waste liquid chamber 9 is also provided on one side of the sample chamber 7 for collecting treated waste liquid.

[0055] The complex mixed multi-form sample injection device is provided with a sample chamber 7 at the injection port 1. This special sample chamber 7 provides an independent area space for mixing the sample and the solvent.

[0056] An oscillator 8 is provided at the bottom of the sample chamber 7. The oscillator 8 can generate mechanical vibrations to promote full mixing of the sample and the injected solvent. After the sample is pretreated with the solvent, it often becomes a homogeneous solution. Through the action of the oscillator 8, the process of full contact and dissolution of the sample and the solvent can be accelerated, the dissolution efficiency can be improved, and the pretreatment effect can be ensured. This setting can set the mixing area of ​​the sample and the solvent independently, avoiding the direct delivery of incompletely dissolved solid particles to the subsequent ionization and detection parts, thereby preventing the ion source from being contaminated and affecting the accuracy of the analysis.

[0057] In addition, a waste liquid chamber 9 is specially provided on one side of the sample chamber 7 to collect incompletely dissolved solid particles, waste solvents and the like.

[0058] Preferably, the solvent configuration module 5 comprises,

[0059] Two solvent storage units 10, respectively used to store solvents of different polarities;

[0060] A proportional valve 11, connected to the outlet ends of the two solvent storage units 10, for adjusting the mixing amount of different solvents according to a preset ratio;

[0061] The solenoid valve 12 is arranged at the outlet of the proportional valve 11 and is used to control the on and off of the mixed solvent;

[0062] The sampling probe 13 is disposed at the outlet end of the electromagnetic valve 12 and is used to inject a mixed solvent into the sample chamber 7 or extract a processed sample.

[0063] In the above structure, the solvent configuration module 5 includes two solvent storage units 10, which respectively store solvents of different polarities, such as polar solvents (such as methanol, ethanol, etc.) and non-polar solvents (such as n-hexane, dichloromethane, etc.). The combination of two solvents of different polarities can cover the dissolution requirements of most samples.

[0064] The outlet ends of the two solvent storage units 10 are connected to a proportional valve 11, which can accurately adjust the mixed amount of the two solvents from the two solvent storage units 10 according to a preset ratio. By changing the mixing ratio, mixed solvents of different polarities can be configured as needed to meet the best matching requirements of different samples.

[0065] The mixed solvent is controlled by a solenoid valve 12 to realize the on-off of the solvent flow. When the solvent needs to be injected, the valve is opened; after the processing is completed, the valve is closed to stop the flow of the solvent.

[0066] An injection probe 13 is provided at the outlet end of the solenoid valve 12. One function of the injection probe 13 is to inject a prepared mixed solvent into the sample chamber 7 to achieve sample dissolution and pretreatment. Another function is to extract the treated homogeneous solution sample and send it to the subsequent ionization and detection part. The process is simple and efficient.

[0067] Preferably, the sample delivery module 6 includes a syringe 14, a plunger pump 15 and a two-position three-way solenoid valve 16. One end of the syringe 14 is connected to the plunger pump 15, and the other end is connected to the two-position three-way solenoid valve 16. One interface of the two-position three-way solenoid valve 16 is connected to the ion source system 17, and the other interface is connected to the solenoid valve 12. The plunger pump 15 is used to control the extraction and injection actions of the syringe 14 to achieve quantitative delivery of the sample.

[0068] In the above structure, one end of the syringe 14 is connected to the plunger pump 15, and the other end is connected to the two-position three-way solenoid valve 16. The syringe 14 is displacement-controlled by the plunger pump 15, so that the sample volume can be accurately quantified, ensuring good repeatability and small error.

[0069] The two-position three-way solenoid valve 16 plays an important function in switching the sample flow path. One of its interfaces is connected to the ion source system 17, and the other interface is connected to the solenoid valve. By controlling the on-off of the two-position three-way solenoid valve 16, it can be determined whether the sample is extracted from the injection probe 13 by the syringe 14, or sent from the syringe 14 to the ion source system 17 for subsequent ionization and detection, which makes the sample flow path switching convenient and greatly simplifies the operation process.

[0070] The basic process of sample delivery is: first, the sampling probe 13 is extended into the sample chamber 7, and then the plunger pump 15 is controlled to make the syringe 14 extract a certain volume of pretreated sample solution from the sampling probe 13, and then, by switching the two-position three-way solenoid valve 16, the sample solution in the syringe 14 is accurately injected into the ion source system 17 to achieve quantitative delivery.

[0071] Preferably, the ion source system 17 comprises,

[0072] The electrospray device 18 is used to atomize the mixed sample, and the electrospray device 18 is connected to an interface of the two-position three-way solenoid valve 16;

[0073] The ion inlet 19 is arranged at the outlet end of the electrospray device 18 and is used to guide the atomized sample into the analysis and detection instrument.

[0074] The ion source system 17 is composed of an electrospray device 18 and an ion inlet 19, and has a very simple and compact structure. The electrospray device 18 is connected to the two-position three-way solenoid valve 16 of the sample delivery module 6. When the syringe 14 delivers a precisely quantitative sample solution, it enters the electrospray device 18. The working principle of the electrospray device 18 is to apply a high-voltage electric field to ionize the solution and atomize it into many charged tiny droplets. Under the action of the electric field, these charged droplets continue to shrink, and eventually the solvent completely evaporates and only the precipitated ions are left. The outlet end of the electrospray device 18 is provided with an ion inlet 19, and the charged ions generated by atomization are efficiently transmitted through the ion inlet 19 and introduced into the subsequent analysis and detection instruments.

[0075] Preferably, the electrospray device 18 comprises,

[0076] A spray needle is connected to an interface of the two-position three-way solenoid valve 16, and a micro hole is provided at the end thereof;

[0077] A coaxial sleeve, arranged around the spray needle, for introducing atomizing gas;

[0078] A heating device, used for heating the spray needle;

[0079] A high voltage power supply is electrically connected to the spray needle.

[0080] In the above structure, the electrospray device 18 is an existing mature technology. One end of the spray needle is connected to the two-position three-way solenoid valve 16 in the sample delivery module 6, from which a precise and quantitative sample solution can be obtained. A tiny hole is provided at the end of the spray needle, and the sample solution is sprayed out from this micropore. The micropore spray method makes the ionization process gentle and avoids the destruction of the molecular structure.

[0081] Surrounding the outside of the spray needle is a coaxial sleeve, which is used to introduce atomization-aiding gases, such as nitrogen, to form a high-speed airflow that accelerates solution spraying and solvent evaporation.

[0082] In order to further improve the solvent evaporation efficiency, the electrospray device 18 is also integrated with a heating device for heating the spray needle to increase the temperature and vapor pressure of the sample solution.

[0083] The electrospray device 18 is connected to a high-voltage power supply. When the sample solution is sprayed out from the micropores, the strong electric field applied by the high-voltage power supply ionizes the solution and atomizes it into charged tiny droplets. Under the action of the electric field force, these charged droplets continuously consume the solvent molecules until only the sample ions are left.

[0084] Preferably, the control unit 4 comprises,

[0085] The signal processing module 20 is electrically connected to the infrared receiver 3 and is used to process the signal received by the infrared receiver 3;

[0086] The polarity determination module 21 is electrically connected to the signal processing module 20 and is used to determine the polarity characteristics of the sample according to the processed signal;

[0087] The solvent ratio module 22 is electrically connected to the polarity judgment module 21 and is used to calculate the optimal ratio of the required solvent according to the polarity characteristics of the sample;

[0088] The control execution module 23 is electrically connected to the solvent configuration module 5 and is used to send a ratio control instruction to the solvent configuration module 5 .

[0089] The design of the control unit 4 combines infrared spectroscopy analysis with solvent configuration, realizing intelligent processing of complex mixed polymorphic samples. First, the signal received by the infrared receiver 3 is processed by the signal processing module 20 to extract the infrared spectral information unique to the sample. Then, the polarity judgment module 21 analyzes the infrared spectral characteristics of the sample based on the processed signal to determine the polarity characteristics of the sample, such as polarity, non-polarity or amphoteric. Next, the solvent ratio module 22 selects the best solvent ratio from the preset solvent database based on the polarity characteristics of the sample and calculates the specific ratio of the required solvent. Finally, the control execution module 23 sends the calculated ratio information to the solvent configuration module 5, controls the solvent configuration module 5 to mix solvents of different polarities according to the preset ratio, and finally configures the most suitable solvent for processing the sample.

[0090] This intelligent control method not only simplifies the operation process and improves work efficiency, but also ensures the accuracy of solvent configuration, effectively improving the accuracy and efficiency of sample analysis.

[0091] Embodiment 2: Figure 1-Figure 2As shown, a mass spectrometry detection device includes the complex mixed multi-form sample injection device in embodiment one.

[0092] This mass spectrometry detection device integrated with a complex mixed multi-form sample injection device realizes intelligent and efficient analysis of complex samples. The complex mixed multi-form sample injection device identifies the polarity characteristics of the sample through the infrared spectrum analysis module, and automatically configures the best solvent according to the polarity characteristics to pre-treat the sample. The treated sample is accurately transported to the ion source system 17 through the sample delivery module 6. The ion source system 17 uses an electrospray device 18 to atomize the sample and generate charged ions. These ions are sent to the mass spectrometer for analysis. The mass spectrometer separates and detects according to the mass-to-charge ratio of the ions, and finally obtains the mass spectrum of the sample.

[0093] The whole process is highly automated and easy to operate, which can effectively improve the efficiency and accuracy of analysis. This design is particularly suitable for analyzing complex mixtures, such as biological samples, environmental samples, and drug samples, and can help researchers gain a deeper understanding of the composition and structure of samples.

[0094] The above are only implementation methods of the present application, and are not intended to limit the patent scope of the present application. Any equivalent structure or equivalent process transformation made using the contents of the present application specification and drawings, or directly or indirectly used in other related technical fields, are also included in the patent protection scope of the present application.

Claims

1. A complex mixed multi-form sample injection device, Features: include, A sample inlet, used for receiving a sample to be tested; An infrared transmitter and an infrared receiver with adjustable wavelength built into the injection port, wherein the infrared transmitter is used to generate infrared light of different wavelengths, and the infrared receiver is used to receive infrared light signals reflected or transmitted by the sample; A control unit, connected to the infrared transmitter and the infrared receiver, for controlling the infrared transmitter to emit infrared light of a specific wavelength and determining the polarity of the sample according to the signal received by the infrared receiver; A solvent configuration module, electrically connected to the control unit, and configured to configure a solvent of corresponding polarity according to the sample polarity determined by the control unit; The sample delivery module is used to mix the solvent configured by the solvent configuration module with the sample and to deliver the processed sample to an analysis and detection instrument.

2. A complex mixed multi-form sample injection device according to claim 1, Features: A sample chamber is arranged at the injection port, an oscillator is arranged at the bottom of the sample chamber, and the oscillator is used to promote the mixing of the sample and the solvent. A waste liquid chamber is also arranged on one side of the sample chamber to collect the treated waste liquid.

3. A complex mixed multi-form sample injection device according to claim 2, Features: The solvent configuration module comprises: Two solvent storage units, respectively used for storing solvents of different polarities; A proportional valve connected to the outlet ends of the two solvent storage units, for adjusting the mixing amount of different solvents according to a preset ratio; A solenoid valve, arranged at the outlet end of the proportional valve, for controlling the on-off of the mixed solvent; The sampling probe is arranged at the outlet end of the electromagnetic valve and is used for injecting a mixed solvent into the sample chamber or extracting a processed sample.

4. A complex mixed multi-form sample injection device according to claim 3, Features: The sample delivery module includes a syringe, a plunger pump and a two-position three-way solenoid valve. One end of the syringe is connected to the plunger pump, and the other end is connected to the two-position three-way solenoid valve. One interface of the two-position three-way solenoid valve is connected to the ion source system, and the other interface is connected to the solenoid valve. The plunger pump is used to control the extraction and injection actions of the syringe to achieve quantitative delivery of the sample.

5. A complex mixed multi-form sample injection device according to claim 4, Features: The ion source system comprises: An electrospray device, used for atomizing the mixed sample, wherein the electrospray device is connected to an interface of the two-position three-way solenoid valve; The ion inlet is arranged at the outlet end of the electrospray device and is used to guide the atomized sample into the analysis and detection instrument.

6. A complex mixed multi-form sample injection device according to claim 5, Features: The electrospray device comprises: A spray needle connected to an interface of the two-position three-way solenoid valve, with a micro hole at the end thereof; A coaxial sleeve, disposed around the spray needle, for introducing atomizing gas; A heating device, used for heating the spray needle; A high voltage power supply is electrically connected to the spray needle.

7. A complex mixed multi-form sample injection device according to claim 1, Features: The control unit comprises, A signal processing module, electrically connected to the infrared receiver, and configured to process a signal received by the infrared receiver; A polarity determination module, electrically connected to the signal processing module, for determining the polarity characteristics of the sample according to the processed signal; A solvent ratio module, electrically connected to the polarity judgment module, for calculating the optimal ratio of the required solvent according to the polarity characteristics of the sample; The control execution module is electrically connected to the solvent configuration module and is used to send a ratio control instruction to the solvent configuration module.

8. A mass spectrometry detection device, Features: It comprises a complex mixed multi-morphological sample injection device as described in any one of claims 1-7.

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