Pipeline fixing device and cell disruption equipment

Abstract

The utility model belongs to the technical field of biological cell chemical breaking equipment, and discloses a pipeline fixing device and cell breaking equipment, the pipeline fixing device comprises a bottom plate, a plurality of supporting columns, a bottom plate and limiting columns, the supporting columns are arranged around the periphery of the bottom plate at intervals, and the limiting columns are arranged on the sides of the supporting columns and spaced from the supporting columns; the conveying pipe is arranged at the interval between the supporting column and the limiting column and spirally arranged around the interval between the limiting column and the supporting column. The pressing plate is connected with the supporting column, the limiting column penetrates through the pressing plate and then is connected with the bottom plate, the height of the top of the supporting column relative to the bottom plate can be adjusted, the pressing plate can move relative to the limiting column, and the height of the pressing plate can be adjusted by adjusting the height of the top of the supporting column relative to the bottom plate so that conveying pipes of different specifications can be matched and fixed. The pipeline fixing device can accommodate conveying pipes of different length specifications, is high in universality and can reduce the occupied space of the conveying pipes.

Description

Technical Field

[0001] The utility model relates to the technical field of biological cell chemical disruption equipment, in particular to a pipeline fixing device and a cell disruption equipment. Background Art

[0002] When biological cells are broken, in order to ensure that the internal substances of the broken biological cells can be fully released, the biological cells need to maintain the broken state for a period of time before subsequent operations can be carried out. Existing cell breaking equipment usually outputs the broken biological cells through a cell breaking reaction tube, but the cell breaking equipment breaks the biological cells in a high-speed and continuous manner. In order to maintain the broken state of the biological cells in the cell breaking reaction pipeline for a sufficient time, the length of the cell breaking reaction tube needs to meet the use requirements, resulting in the cell breaking reaction tube contained in the existing cell breaking equipment occupying a large space and being inconvenient to store, which is inconvenient for the staff to operate the cell breaking equipment. At the same time, the lengths of the cell breaking reaction tubes in different cell breaking equipment are inconsistent, resulting in the need to match and use storage components of different specifications to store them, making it more difficult for the staff to store the cell breaking reaction tubes.

[0003] Therefore, there is an urgent need for a pipeline fixing device and a cell disruption device to solve the above technical problems. Utility Model Content

[0004] The first purpose of the utility model is to provide a pipeline fixing device, which can accommodate cell disruption reaction tubes, reduce the space occupied by the tubes, reduce the work difficulty of the staff, can accommodate cell disruption reaction tubes of different lengths and specifications, and has high versatility.

[0005] To achieve this purpose, the utility model adopts the following technical solutions:

[0006] Pipeline fixture, including:

[0007] A bottom plate and a plurality of support columns, wherein the plurality of support columns are arranged at intervals around the bottom plate, and the height of the top of the support column relative to the bottom plate can be adjusted;

[0008] A pressing plate connected to the supporting column;

[0009] The limiting column is located beside the supporting column and has a gap with the supporting column. The limiting column passes through the pressing plate and is connected to the bottom plate. The pressing plate can move relative to the limiting column. The conveying pipe is placed spirally around the interval between the limiting column and the supporting column.

[0010] As a preferred technical solution for the pipeline fixing device, the support column is a telescopic structure.

[0011] As an optimal technical solution for the pipeline fixing device, a plurality of positioning holes are arranged on the base plate, and the plurality of positioning holes are arranged at intervals around the base plate. The outer periphery of the support column is provided with an external thread, and the positioning hole has an internal thread. The base plate is connected to the support column via the internal thread.

[0012] As a preferred technical solution of the pipeline fixing device, the pipeline fixing device further includes a gasket, which is used to adjust the height of the delivery pipe, and the number of the gaskets increases successively along the surrounding path of the delivery pipe.

[0013] As a preferred technical solution for the pipeline fixing device, the area where the base plate is not connected to the support column is hollowed out.

[0014] As a preferred technical solution for the pipeline fixing device, limiting columns are provided on both sides of each of the support columns.

[0015] As a preferred technical solution of the pipeline fixing device, the pipeline fixing device also includes a reinforcement plate, and the reinforcement plate is closely connected to the bottom of the base plate.

[0016] As a preferred technical solution of the pipeline fixing device, the pipeline fixing device also includes a connecting frame, which is connected to the bottom plate or the reinforcement plate, and the connecting frame is used to connect to the inner wall of the cell disruption device.

[0017] As a preferred technical solution for the pipeline fixing device, the base plate, the support column, the pressure plate and the limiting column are all made of metal.

[0018] The second purpose of the utility model is to provide a cell disruption device. To achieve this purpose, the utility model adopts the following technical solutions:

[0019] A cell disruption device comprises any one of the above-mentioned pipeline fixing devices, the cell disruption device further comprises a cell disruption chamber and a delivery pipe, the delivery pipe is connected to the cell disruption chamber and is used to transport the disrupted biological cells, and the delivery pipe is coiled on the pipeline fixing device.

[0020] The beneficial effects of the utility model are:

[0021] The pipeline fixing device provided by the utility model is arranged at intervals around the bottom plate by a plurality of support columns, the limiting columns are placed beside the support columns and are spaced apart from the support columns, the delivery pipe is placed between the support columns and the limiting columns, and the delivery pipe is placed spirally around the interval between the support columns and the limiting columns, so as to store the delivery pipe and reduce the occupied space of the delivery pipe, wherein the delivery pipe is a cell crushing reaction tube; the pressing plate is connected to the support columns, and the limiting columns penetrate the pressing plate and are connected to the bottom plate, so that the pressing plate is pressed against the top of the delivery pipe to fix the delivery pipe in the vertical direction. Prevent the conveying tube from deforming when the broken cells flow at high speed, and realize stable conveying of broken cells; because the height of the top of the support column relative to the bottom plate can be adjusted, the pressure plate is connected to the support column, and the pressure plate can move relative to the limit column, so the height of the pressure plate relative to the bottom plate can be adjusted with the movement of the support column, so for conveying tubes of different lengths, when they are placed around the support column and the limit column, the staff only needs to adjust the height of the support column relative to the bottom plate, thereby adjusting the height of the pressure plate, and can fix conveying tubes of different specifications, thereby improving the overall versatility of the pipeline fixing device. The cell crushing device provided by the utility model can effectively store cell crushing reaction tubes, the overall space occupied is small, and there are fewer residual broken cells inside, and the broken cells can be discharged to a greater extent. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a structural schematic diagram of the pipeline fixing device provided by the utility model;

[0023] Figure 2 The utility model is a schematic diagram of the assembly of the pipeline fixing device and the delivery pipe.

[0024] In the figure:

[0025] 100. Delivery pipe;

[0026] 1. Base plate; 2. Support column; 3. Pressure plate; 4. Limit column; 5. Gasket; 6. Reinforcement plate; 7. Connecting frame. DETAILED DESCRIPTION

[0027] The present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It is to be understood that the specific embodiments described herein are only used to explain the present invention, rather than to limit the present invention. It should also be noted that, for ease of description, only the parts related to the present invention, rather than all structures, are shown in the accompanying drawings.

[0028] In the description of the present invention, unless otherwise clearly specified and limited, the terms "connected", "connected", and "fixed" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0029] In the present utility model, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may include that the first and second features are in direct contact, or may include that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, a first feature being "above", "above" and "above" a second feature includes that the first feature is directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below", "below" and "below" a second feature includes that the first feature is directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.

[0030] In the description of this embodiment, the terms "upper", "lower", "right", etc., are based on the directions or positions shown in the drawings, and are only for the convenience of description and simplified operation, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation of the present invention. In addition, the terms "first" and "second" are only used to distinguish in the description and have no special meaning.

[0031] Embodiment 1

[0032] like Figure 1 and Figure 2As shown, this embodiment provides a pipeline fixing device, which is placed inside the cell crushing device and is used to spirally fix the delivery pipe 100, wherein the delivery pipe 100 is a cell crushing reaction tube, and the pipeline fixing device includes a bottom plate 1, a plurality of support columns 2, a pressure plate 3 and a limiting column 4. The plurality of support columns 2 are arranged at intervals around the bottom plate 1, the limiting column 4 is placed beside the support column 2 and is spaced apart from the support column 2, the delivery pipe 100 is placed between the support column 2 and the limiting column 4, and the delivery pipe 100 is spirally placed around the interval between the support column 2 and the limiting column 4, so as to store the delivery pipe 100 and reduce the occupied space of the delivery pipe 100. The pressure plate 3 is threadedly connected to the support column 2 and is located at the top of the support column 2, and the limiting column 4 penetrates the pressure plate 3 and is connected to the bottom plate 1, so that the pressure plate 3 is pressed against the top of the delivery pipe 100, and the delivery pipe 100 is fixed in the vertical direction to prevent the delivery pipe 100 from deforming when the crushed cells flow at a high speed, so as to realize stable delivery of the crushed cells. At the same time, the setting of the pressing plate 3 can fix the inlet and outlet of the conveying tube 100, ensuring that the broken cells can be stably transported along the conveying tube 100.

[0033] The height of the top of the support column 2 relative to the base plate 1 can be adjusted, and the pressing plate 3 is connected to the support column 2, and the pressing plate 3 can move relative to the limiting column 4. Therefore, the pressing plate 3 will move with the movement of the support column 2, and then the height of the pressing plate 3 relative to the base plate 1 can be adjusted. In this way, for conveying pipes 100 of different lengths, after they are placed around the support column 2 and the limiting column 4, the staff only needs to adjust the height of the support column 2 relative to the base plate 1, thereby adjusting the height of the pressing plate 3, so as to fix conveying pipes 100 of different specifications. In this way, one pipeline fixing device can be used to store and fix conveying pipes 100 of different lengths, thereby improving the versatility of the pipeline fixing device and reducing the difficulty of storing the conveying pipe 100 for the staff.

[0034] Regarding the height adjustment of the top of the support column 2 relative to the base plate 1, for example, the support column 2 can be set as a telescopic structure, and the support column 2 is fixedly connected to the base plate 1. By adjusting the telescopic degree of the support column 2, the height of the top of the support column 2 relative to the base plate 1 can be adjusted.

[0035] In another example, an external thread can be set on the outer periphery of the support column 2, and a plurality of positioning holes can be set at intervals around the base plate 1, and an internal thread can be set in the positioning holes. The support column 2 is threadedly connected to the base plate 1, and the height of the top of the support column 2 relative to the base plate 1 can be adjusted by rotating the support column 2 clockwise or counterclockwise. Therefore, as long as the height of the top of the support column 2 relative to the base plate 1 can be adjusted, the specific scheme is not limited.

[0036] Preferably, the pipeline fixing device also includes a gasket 5, which is located on the upper surface of the base plate 1, and specifically at the connection between the support column 2 and the base plate 1. When the delivery pipe 100 is placed at the interval between the support column 2 and the limiting column 4, the gasket 5 is located below the delivery pipe 100 to adjust the height of the delivery pipe 100, wherein the number of gaskets 5 increases successively along the circumferential path of the delivery pipe 100, so that the delivery pipe 100 is in an inclined state, wherein the pipe mouth of the spiraled delivery pipe 100 at a high position is an inlet, from which the broken cells enter, and the pipe mouth at a low position is an outlet, from which the broken cells are output, so that the broken cells are discharged along the inclined delivery pipe 100, so that the broken cells remaining in the delivery pipe 100 are further discharged, the residual amount of broken cells in the delivery pipe 100 is reduced, and the waste of broken cells is reduced.

[0037] Preferably, the area on the base plate 1 that is not connected to the support column 2 is of hollow design, which can reduce the overall weight while ensuring the strength of the pipeline fixture and facilitate the staff to take the pipeline fixture.

[0038] Preferably, limiting columns 4 are provided on both sides of each support column 2, so that two delivery tubes 100 can be separately coiled on both sides of the support column 2, thereby increasing the number of delivery tubes 100 that can be accommodated by the pipeline fixing device, and simultaneously outputting more broken cells.

[0039] In this embodiment, the pipeline fixing device further includes a reinforcing plate 6, which is arranged below the bottom plate 1, and the two are locked by a locking member, and bolts can be selected for the locking member, so that the bottom plate 1 can bear a heavier weight of the delivery pipe 100, further improving the structural stability of the pipeline fixing device. The reinforcing plate 6 is a hollow design, and the hollow position of the reinforcing plate 6 is consistent with the hollow position of the bottom plate 1, so as to reduce the overall weight of the pipeline fixing device.

[0040] In this embodiment, the pipeline fixing device also includes a connecting frame 7, which can be directly connected to the base plate 1, or can also be connected to the reinforcement plate 6. The staff can selectively assemble it according to needs. The connecting frame 7 is formed by bending an iron plate. An equipment mounting frame is arranged inside the cell crushing device. The mounting frame is assembled in combination with the connecting frame 7 to place the pipeline fixing device inside the cell crushing device. The use of the connecting frame 7 needs to be selectively assembled according to the specific structure of the cell crushing device. The cell crushing device of some specifications has a crushed cell outlet arranged inside it, and then the connecting frame 7 and the mounting frame need to be used. Conversely, the cell crushing device of some specifications has a crushed cell outlet arranged outside it, so there is no need to use the mounting frame. The assembly of the mounting frame needs to be selected according to the specific structure of the cell crushing device.

[0041] Preferably, the reinforcing plate 6, the bottom plate 1, the limiting column 4 and the pressing plate 3 are made of metal. Thus, if the delivery tube 100 is damaged and the broken cells flow out and stick to the surface of the pipe fixing device, the staff can easily clean them from the pipe fixing device, so that the pipe fixing device can be used later.

[0042] Embodiment 2

[0043] This embodiment provides a cell disruption device, including the pipeline fixing device in the first embodiment, and the cell disruption device also includes a cell disruption chamber (not shown in the figure) and a delivery pipe 100. The inlet of the delivery pipe 100 is connected to the cell disruption chamber for transporting the disrupted biological cells. The delivery pipe 100 is coiled on the pipeline fixing device.

[0044] The cell disruption device provided in this embodiment can effectively accommodate the delivery tube 100, occupies a small space as a whole, and has fewer residual disrupted cells inside, so that the disrupted cells can be discharged to a greater extent.

[0045] Obviously, the above embodiments of the present invention are merely examples for the purpose of clearly illustrating the present invention, and are not intended to limit the implementation methods of the present invention. For those skilled in the art, various obvious changes, readjustments and substitutions can be made without departing from the scope of protection of the present invention. It is not necessary and impossible to list all implementation methods here. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention shall be included in the scope of protection of the claims of the present invention.

Claims

1. A pipeline fixing device, characterized in that: include: A base plate (1) and a plurality of support columns (2), wherein the plurality of support columns (2) are arranged at intervals around the base plate (1), and the height of the top of the support column (2) relative to the base plate (1) can be adjusted; A pressing plate (3) connected to the supporting column (2); A limiting column (4) is located beside the support column (2) and has a gap with the support column (2). The limiting column (4) passes through the pressure plate (3) and is connected to the bottom plate (1). The pressure plate (3) can move relative to the limiting column (4). The conveying pipe (100) is placed in a spiral around the interval between the limiting column (4) and the support column (2).

2. The pipeline fixing device according to claim 1, characterized in that: The support column (2) is a telescopic structure.

3. The pipeline fixing device according to claim 1, characterized in that: The base plate (1) is provided with a plurality of positioning holes, the plurality of positioning holes being arranged at intervals around the base plate (1), the outer periphery of the support column (2) being provided with an external thread, the positioning holes having an internal thread, and the base plate (1) being connected to the support column (2) via the internal thread.

4. The pipeline fixing device according to claim 1, characterized in that: The pipeline fixing device further comprises a gasket (5), wherein the gasket (5) is used to adjust the height of the delivery pipe (100), and the number of the gaskets (5) increases in sequence along the surrounding path of the delivery pipe (100).

5. The pipeline fixing device according to claim 1, characterized in that: The area of ​​the bottom plate (1) that is not connected to the support column (2) is of hollow design.

6. The pipeline fixing device according to claim 1, characterized in that: Limiting columns (4) are arranged on both sides of each supporting column (2).

7. The pipeline fixing device according to claim 1, characterized in that: The pipeline fixing device also includes a reinforcing plate (6), and the reinforcing plate (6) is closely connected to the bottom of the base plate (1).

8. The pipeline fixing device according to claim 7, characterized in that: The pipeline fixing device also includes a connecting frame (7), the connecting frame (7) is connected to the bottom plate (1) or the reinforcing plate (6), and the connecting frame (7) is used to be connected to the inner wall of the cell disruption device.

9. The pipeline fixing device according to claim 1, characterized in that: The base plate (1), the support column (2), the pressure plate (3) and the limiting column (4) are all made of metal.

10. A cell disruption device, characterized in that: The invention comprises the pipeline fixing device according to any one of claims 1 to 9, wherein the cell disruption equipment further comprises a cell disruption chamber and a delivery pipe (100), wherein the delivery pipe (100) is connected to the cell disruption chamber and is used to transport the disrupted biological cells, and the delivery pipe (100) is coiled on the pipeline fixing device.

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