Automatic filling device for cell culture medium

By designing an automatic filling device, the precise and automatic injection of test tube liquid is achieved using airbags and spring mechanisms, which solves the problem of high labor intensity in traditional manual filling and improves the efficiency of cell culture.

CN222250773UActive Publication Date: 2024-12-27HUAXIAYUAN (JIANGSU) CELL GENE ENGINEERING GROUP CO LTD
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Patent Information

Application Number
CN202420236478.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-01-30
Publication Date
2024-12-27
Estimated Expiration
2034-01-30

AI Technical Summary

Technical Problem

The labor intensity of traditional manual refill cell culture medium is high, resulting in low cell culture efficiency and difficulty in improving.

Method used

An automatic filling device including an adjustment mechanism and an extraction device is designed. Using airbags and spring mechanisms, the precise automatic injection of test tube liquid into the culture medium container is realized, reducing labor intensity and improving efficiency.

Benefits of technology

Automatic replenishment of cell culture medium is achieved, reducing labor intensity, improving the efficiency of cell culture, and improving the working effect of the airbag and the extraction efficiency of the extraction tube through the spring mechanism.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of cell culture, and discloses an automatic cell culture medium filling device which comprises a working table, a sliding plate is fixedly connected in the working table, a tray is connected to the upper end of the sliding plate in a sliding mode, a culture medium container is connected to the tray, a test tube container is connected to the tray, and the test tube container is connected to the working table. An adjusting mechanism is arranged in the workbench, an extracting device is connected to the adjusting mechanism, the adjusting mechanism comprises a first air cylinder, the output end of the first air cylinder is fixedly connected with a first telescopic rod, and the first air cylinder is fixedly connected with the workbench; the end, away from the first air cylinder, of the first telescopic rod is fixedly connected with a second air cylinder, the beneficial effects of reducing labor intensity and improving the cell culture efficiency are achieved, and the problems that in the prior art, traditional manual filling is high in labor intensity, large in working time consumption and difficult to improve the cell culture efficiency are solved.
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Description

Technical Field

[0001] The utility model relates to the technical field of cell culture, in particular to an automatic filling device for cell culture medium. Background Art

[0002] Cell culture refers to the process of growing and multiplying cells in vitro under appropriate conditions, usually in a laboratory. This technology is widely used in biomedical research, drug development, bioengineering and other fields. The automatic filling device for cell culture medium is a device used to automatically add culture medium regularly during the cell culture process. It is widely used in cell culture experiments in biomedical research and other fields.

[0003] In current technology, when a cell culture flask is in use, since cells such as germ cells need to be expanded and cultured, cell culture medium needs to be added to the cell culture flask. However, the traditional manual filling is labor-intensive and time-consuming, which makes it difficult to improve the efficiency of cell culture. Utility Model Content

[0004] The utility model provides an automatic filling device for cell culture medium, which has the beneficial effects of reducing labor intensity and improving the efficiency of cell culture, and solves the problem mentioned in the above background technology that traditional manual filling has high labor intensity, causes a lot of time consumption, and makes it difficult to improve the efficiency of cell culture.

[0005] The utility model provides the following technical solution: an automatic filling device for cell culture medium, comprising a workbench, a sliding plate fixedly connected to the interior of the workbench, a tray slidably connected to the upper end of the sliding plate, a culture medium container connected to the tray, a test tube container connected to the tray, an adjustment mechanism provided inside the workbench, and an extraction device connected to the adjustment mechanism.

[0006] As an optional solution of the automatic filling device of the cell culture medium described in the utility model, the regulating mechanism includes a first cylinder, the output end of the first cylinder is fixedly connected to a first telescopic rod, and the first cylinder is fixedly connected to the workbench.

[0007] As an optional solution of the automatic filling device of the cell culture medium described in the utility model, wherein: the end of the first telescopic rod away from the first cylinder is fixedly connected to the second cylinder, the output end of the second cylinder is fixedly connected to the second telescopic rod, the bottom of the second telescopic rod is fixedly connected to a connecting plate, and the connecting plate is connected to the extraction device.

[0008] As an optional solution of the automatic filling device of the cell culture medium described in the utility model, wherein: a sliding block is fixedly connected to the second cylinder, a sliding rod is slidably connected inside the sliding block, and the sliding rod is fixedly connected to the workbench.

[0009] As an optional solution of the automatic filling device of the cell culture medium described in the utility model, the extraction device includes a third cylinder, the third cylinder is fixedly connected to the fixed plate, and the output end of the third cylinder is fixedly connected to a third telescopic rod.

[0010] As an optional solution of the automatic filling device of the cell culture medium described in the utility model, the extraction device also includes an operating tube, the upper end of the operating tube is fixedly connected to the fixed plate, the interior of the operating tube is slidably connected to an upper pressing plate, and the upper pressing plate is fixedly connected to the third telescopic rod.

[0011] As an optional solution of the automatic filling device of the cell culture medium described in the utility model, wherein: the interior of the operating tube is fixedly connected to a support plate, the upper end of the support plate is fixedly connected to an air bag, the interior of the air bag is fixedly connected to a spring, and the bottom of the air bag is connected to an extraction tube.

[0012] As an optional solution of the automatic filling device for cell culture medium of the utility model, wherein: the bottom of the operation tube is fixedly connected with a fixing sleeve, and the interior of the fixing sleeve is fixedly connected with the extraction tube.

[0013] The utility model has the following beneficial effects:

[0014] 1. This automatic filling device for cell culture medium, by setting an adjustment mechanism and an extraction device, extracts the liquid in the test tube container into the inside of the extraction tube and the air bag under the action of the air bag, and then cooperates with the adjustment mechanism to accurately inject the liquid into the inside of the culture medium container, so as to achieve the purpose of automatic filling of cell culture medium and realize the beneficial effects of reducing labor intensity and improving the efficiency of cell culture.

[0015] 2. This automatic filling device for cell culture medium is provided with a spring. When the airbag is not subjected to external force, the spring quickly expands the airbag to expand the space inside the airbag, thereby avoiding the problem that when the airbag is squeezed by the third telescopic rod, the compressed spring is not able to rebound in time, resulting in the extraction tube being unable to extract liquid in time, thereby achieving the purpose of improving the working effect of the airbag and realizing the beneficial effect of improving the extraction efficiency of the extraction tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a structural schematic diagram of the utility model.

[0017] Figure 2It is a schematic diagram of the adjustment mechanism of the utility model.

[0018] Figure 3 It is a cross-sectional schematic diagram of the operating pipe of the utility model.

[0019] Figure 4 For this utility model Figure 3 A magnified schematic diagram of center A.

[0020] In the figure: 1. workbench; 2. sliding plate; 3. tray; 4. culture medium container; 5. test tube container; 6. adjustment mechanism; 601. first cylinder; 602. first telescopic rod; 603. second cylinder; 604. second telescopic rod; 605. connecting plate; 606. sliding block; 607. sliding rod; 7. extraction device; 701. third cylinder; 702. third telescopic rod; 703. operating tube; 704. upper pressure plate; 705. support plate; 706. air bag; 707. spring; 708. extraction tube; 8. fixing sleeve. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0022] Embodiment 1

[0023] See also Figures 1 to 4 , including a workbench 1, a sliding plate 2 is fixedly connected to the inside of the workbench 1, and a tray 3 is slidably connected to the upper end of the sliding plate 2. In order to maintain the balance of the tray 3, at least two sliding plates 2 are provided and the length direction of the sliding plates 2 is the same as the sliding direction of the sliding plates 2. A culture medium container 4 is connected to the tray 3, and a test tube container 5 is connected to the tray 3. An adjustment mechanism 6 is provided inside the workbench 1, and an extraction device 7 is connected to the adjustment mechanism.

[0024] The adjusting mechanism 6 comprises a first cylinder 601 , an output end of the first cylinder 601 is fixedly connected to a first telescopic rod 602 , and the first cylinder 601 is fixedly connected to the workbench 1 .

[0025] One end of the first telescopic rod 602 away from the first cylinder 601 is fixedly connected to the second cylinder 603, the output end of the second cylinder 603 is fixedly connected to the second telescopic rod 604, the bottom of the second telescopic rod 604 is fixedly connected to a connecting plate 605, and the connecting plate 605 is connected to the extraction device 7. By setting the connecting plate 605, the adjustment mechanism 6 and the extraction device 7 are connected together, so as to transfer the extracted liquid to a designated position.

[0026] A sliding block 606 is fixedly connected to the second cylinder 603. Two sliding blocks 606 are provided and are respectively fixed on both sides of the second cylinder 603. A sliding rod 607 is slidably connected inside the sliding block 606. The sliding rod 607 is fixedly connected to the workbench 1, and the outer side of the sliding rod 607 matches the inner side of the sliding block 606.

[0027] The extraction device 7 comprises a third cylinder 701 , which is fixedly connected to the fixing plate, and an output end of the third cylinder 701 is fixedly connected to a third telescopic rod 702 .

[0028] The extraction device 7 also includes an operating tube 703, the upper end of which is fixedly connected to the fixed plate, and the interior of the operating tube 703 is slidably connected to an upper pressing plate 704, the shape of which matches the interior of the operating tube 703, and the upper pressing plate 704 is fixedly connected to the third telescopic rod 702.

[0029] The inside of the operating tube 703 is fixedly connected to a support plate 705, the upper end of the support plate 705 is fixedly connected to an airbag 706, the inside of the airbag 706 is fixedly connected to a spring 707, the bottom of the airbag 706 is connected to an extraction tube 708, and the extraction tube 708 passes through the support plate 705 and extends out from the bottom of the operating tube 703.

[0030] The working principle of this embodiment is as follows: when in use, the culture medium container 4 and the test tube container 5 are placed into the tray 3, the tray 3 is pushed into the workbench 1, the first cylinder 601 is started, the first cylinder 601 drives the second cylinder 603 to slide on the sliding rod 607, the second cylinder 603 drives the fixed plate to move on the culture medium container 4 and the test tube container 5, when the operating tube 703 on the fixed plate is located at the upper end of the test tube container 5, the third cylinder 701 is started, the third cylinder 701 drives the third telescopic rod 702 to squeeze the airbag 706, the air inside the airbag 706 is discharged, and the second cylinder 603 is controlled to make the bottom of the extraction tube 708 contact The liquid inside the test tube, at this time, the third cylinder 701 is started to make the third telescopic rod 702 move in the opposite direction, and under the action of the spring 707, the spring 707 opens the airbag 706, and the airbag 706 absorbs the liquid inside the test tube through the extraction tube 708, and stores the liquid in the extraction tube 708 and the airbag 706. By controlling the adjustment mechanism 6, the bottom of the extraction tube 708 is aligned with the upper end of the culture medium container 4, and the third cylinder 701 is started. The third cylinder 701 drives the third telescopic rod 702 to squeeze the airbag 706, and squeezes the liquid inside the extraction tube 708 and the airbag 706 into the culture medium container 4, thereby achieving the purpose of automatic liquid filling.

[0031] Embodiment 2

[0032] This embodiment is an improvement made on the basis of embodiment 1. For details, please refer to Figures 1 to 4 The bottom of the operating tube 703 is fixedly connected with a fixing sleeve 8, and the interior of the fixing sleeve 8 is fixedly connected with the extraction tube 708.

[0033] The working principle of this embodiment is as follows: when liquid passes through the extraction tube 708, the extraction tube 708 is subjected to the impact force of the liquid. Since the extraction tube 708 is too long and the contact area with the operating tube 703 is too small, the extraction tube 708 shakes, which causes the liquid to easily spill when being extracted. This problem can be solved by providing a fixed sleeve 8. By providing the fixed sleeve 8, when the liquid passes through the extraction tube 708, the fixed sleeve 8 fixes one side of the extraction tube 708 to the bottom of the operating tube 703. Under the action of the fixed sleeve 8, the fixed sleeve 8 increases the contact area between the extraction tube 708 and the operating tube 703, thereby avoiding the extraction tube 708 being subjected to the impact force of the liquid when the liquid passes through the extraction tube 708. Since the extraction tube 708 is too long and the contact area with the operating tube 703 is too small, the extraction tube 708 shakes, which causes the liquid to easily spill when being extracted, thereby achieving the purpose of fixing the extraction tube 708 and improving the effect of extracting liquid.

[0034] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0035] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the technical principle of the present invention. These improvements and modifications should also be regarded as the protection scope of the present invention.

Claims

1. An automatic filling device for cell culture medium, comprising a workbench (1), characterized in that: The workbench (1) is fixedly connected to a sliding plate (2) inside, the sliding plate (2) is slidably connected to a tray (3) at its upper end, the tray (3) is connected to a culture medium container (4), the tray (3) is connected to a test tube container (5), and an adjustment mechanism (6) is provided inside the workbench (1), and an extraction device (7) is connected to the adjustment mechanism; The adjusting mechanism (6) comprises a first cylinder (601), the output end of the first cylinder (601) is fixedly connected to a first telescopic rod (602), and the first cylinder (601) is fixedly connected to the workbench (1); The extraction device (7) comprises a third cylinder (701), the third cylinder (701) is fixedly connected to a fixing plate, and the output end of the third cylinder (701) is fixedly connected to a third telescopic rod (702).

2. The automatic filling device for cell culture medium according to claim 1, characterized in that: One end of the first telescopic rod (602) away from the first cylinder (601) is fixedly connected to the second cylinder (603), the output end of the second cylinder (603) is fixedly connected to the second telescopic rod (604), the bottom of the second telescopic rod (604) is fixedly connected to a connecting plate (605), and the connecting plate (605) is connected to the extraction device (7).

3. The automatic filling device for cell culture medium according to claim 2, characterized in that: A sliding block (606) is fixedly connected to the second cylinder (603), a sliding rod (607) is slidably connected inside the sliding block (606), and the sliding rod (607) is fixedly connected to the workbench (1).

4. The automatic filling device for cell culture medium according to claim 3, characterized in that: The extraction device (7) further comprises an operating tube (703), the upper end of the operating tube (703) being fixedly connected to the fixing plate, the interior of the operating tube (703) being slidably connected to an upper pressing plate (704), and the upper pressing plate (704) being fixedly connected to the third telescopic rod (702).

5. The automatic filling device for cell culture medium according to claim 4, characterized in that: The operating tube (703) is fixedly connected to a support plate (705) at its interior, an air bag (706) is fixedly connected to the upper end of the support plate (705), a spring (707) is fixedly connected to the interior of the air bag (706), and the bottom of the air bag (706) is connected to an extraction tube (708).

6. The automatic filling device for cell culture medium according to claim 5, characterized in that: A fixing sleeve (8) is fixedly connected to the bottom of the operating tube (703), and the interior of the fixing sleeve (8) is fixedly connected to the extraction tube (708).