Chromosome piece baking and dyeing all-in-one machine
The all-in-one machine automates chromosome slide processing through a collaborative robot and integrated systems, addressing inefficiencies and biosafety issues in manual methods, ensuring high-quality chromosome preparation.
Patent Information
- Application Number
- CN202420906568.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-28
- Publication Date
- 2024-12-27
- Estimated Expiration
- 2034-04-28
AI Technical Summary
Manual chromosome preparation processes are tedious, laborious, inefficient, and prone to biosafety accidents, leading to poor preparation effects and affecting accurate diagnosis.
An all-in-one machine for chromosome baking and staining that integrates a six-axis collaborative robot, electric grippers, ovens, liquid tanks, and a water bath, enabling automated chromosome slide handling, baking, dyeing, and drying processes.
Automates chromosome slide processing, reducing manual labor, improving efficiency, and ensuring consistent quality by integrating baking and dyeing steps, thereby avoiding poor production results.
Smart Images
Figure CN222258900U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of biological sample experiments, in particular to a chromosome baking and staining integrated machine. Background Art
[0002] Chromosome karyotype analysis is particularly important in the diagnosis of chromosomal diseases. With the promotion of chromosome karyotype analysis projects and the increase in clinical testing needs, the amount of specimens is also increasing, and the requirements for the skills of experimental personnel and the effect of chromosome preparation are also increasing. In the preparation process, the cell suspension is sucked with a pipette and dropped on a pre-cooled clean glass slide at an appropriate height. After baking in a 75°C oven for 2 hours, the staining operation is performed. At present, the staining and baking steps are manual single operations, which are tedious and laborious, inefficient, and prone to biosafety accidents during the experiment. Factors such as manual operation and reagent environment can easily lead to poor preparation effects and affect the accurate diagnosis of chromosomes. Utility Model Content
[0003] In order to solve the problems of the above-mentioned prior art, the utility model provides an all-in-one machine for chromosome baking and staining, which solves the problem of manual single operation in each link of production, which is tedious, laborious and inefficient, and avoids the problem of poor production effect caused by manual operation.
[0004] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a chromosome baking and staining machine, comprising an external shell and an operating table placed inside the external shell, a six-axis collaborative robot is fixedly connected to the inner top surface of the external shell, an electric clamp is installed on the operating end of the six-axis collaborative robot, an oven and a water bath are arranged on the operating table, a plurality of liquid tanks for chromosome staining are installed in the water bath, a placement rack is slidably connected to the operating table, and the placement rack can be pulled out from the external shell to replenish chromosome slides.
[0005] With the above structural design, the six-axis collaborative robot uses electric grippers to grip the placement rack filled with chromosome slides, puts the chromosome slides into the oven, and after the baking is completed, the chromosome slides are placed in the liquid tank for dyeing by the electric grippers. After the dyeing is completed, the slides are placed in the oven to dry the water droplets on the surface of the chromosome slides, and finally the placement rack is pulled out of the external shell. This process achieves the purpose of automatic baking and dyeing integration, is simple to operate, saves manpower, and solves the problems of tedious, laborious and inefficient manual operation in each link of the production process, while avoiding the problem of poor production results caused by manual operation.
[0006] Preferably, a cover plate is hinged at one end of the oven, a telescopic rod is rotatably connected to one side of the cover plate, and the other end of the telescopic rod is rotatably connected to one side of the oven.
[0007] With the above structural design, the automatic opening and closing of the oven cover is realized through the cooperation of the telescopic rod and the cover plate, thereby realizing the automation of baking slices.
[0008] Preferably, a magnetic rotation module is installed on the lower surface of the water bath, the position and number of the magnetic rotation module correspond to the liquid tank, a magnetic rotor is arranged inside the liquid tank, and the magnetic rotation module can control the rotation of the magnetic rotor.
[0009] By adopting the above structural design, the rotation of the magnetic rotor is controlled by the magnetic rotation module, which speeds up the dyeing speed, shortens the dyeing time, and saves time cost.
[0010] Preferably, a telescopic top rod is installed on one side of the operating table, and the upper end of the telescopic top rod is rotatably connected to a rotating rod. The rotating rod passes through the operating table and is provided with a temperature sensor, and the detection part of the temperature sensor can extend into the liquid tank.
[0011] With the above structural design, the temperature sensor can detect the temperature of the liquid in the liquid tank in real time, which is convenient for the operator to better control the temperature. When it is necessary to change the water in the liquid tank, the telescopic top rod is started to lift the temperature sensor and rotate it to one side of the liquid tank, which is convenient for the operator to change the water in the liquid tank.
[0012] Preferably, a water exchange pump is fixedly connected to one side of the operating table, and the water exchange pump connects the water bath to an external water tank through a water pipe.
[0013] By adopting the above structural design, the water in the water bath can be changed by the water changing pump without opening the external shell, thereby improving the automation of the device.
[0014] Compared with the prior art, the beneficial effects of the utility model are:
[0015] The six-axis collaborative robot uses an electric gripper to grab the placement rack filled with chromosome slides, puts the chromosome slides into the oven, and after the baking is completed, the electric gripper places the chromosome slides in the liquid tank for dyeing. After the dyeing is completed, the slides are placed in the oven to dry the water droplets on the surface of the chromosome slides, and finally the placement rack is pulled out of the external shell. This process achieves the purpose of automatic baking and dyeing integration, is simple to operate, saves manpower, and solves the problems of tedious, laborious and inefficient manual operation in each link of the production process, while avoiding the problem of poor production results caused by manual operation. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] Figure 1 It is a schematic diagram of the structure of the utility model;
[0017] Figure 2 It is a side view of the utility model;
[0018] Figure 3 It is a top view of the utility model. DETAILED DESCRIPTION
[0019] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0020] See also Figure 1-3 The utility model provides a technical solution: a chromosome baking and staining machine, comprising an external shell 8 and an operating table 1 placed inside the external shell 8, a six-axis collaborative robot 2 is fixedly connected to the internal top surface of the external shell 8, an operating end of the six-axis collaborative robot 2 is equipped with an electric clamp 21, an oven 3 and a water bath 4 are arranged on the upper part of the operating table 1, a plurality of liquid tanks 5 for chromosome staining are installed in the water bath 4, a placement rack 7 is slidably connected to the operating table 1, and the placement rack 7 can be pulled out from the external shell 8 to replenish chromosome slides. The six-axis collaborative robot 2 clamps the placement rack 7 filled with chromosome slides through the electric gripper 21, puts the chromosome slides into the oven 3, and after the baking is completed, the chromosome slides are placed in the liquid tank 5 for dyeing through the electric gripper 21. After the dyeing is completed, the slides are placed in the oven 3 to dry the water droplets on the surface of the chromosome slides, and finally the placement rack 7 is pulled out from the external shell 8. This process achieves the purpose of automatic baking and dyeing, is simple to operate, saves manpower, and solves the problems of manual single operation in each link of the production, which is tedious, laborious and inefficient, and at the same time avoids the problem of poor production effect caused by manual operation.
[0021] The oven 3 has a cover plate 31 hinged at one end, a telescopic rod 32 is rotatably connected to one side of the cover plate 31, and the other end of the telescopic rod 32 is rotatably connected to one side of the oven 3. The automatic opening and closing of the cover of the oven 3 is realized by the cooperation of the telescopic rod 32 and the cover plate 31, so that the baking process is automated.
[0022] A magnetic rotation module 51 is installed on the lower surface of the water bath 4, and the position and number of the magnetic rotation module 51 correspond to the liquid tank 5. A magnetic rotor 52 is arranged inside the liquid tank 5, and the magnetic rotation module 51 can control the rotation of the magnetic rotor 52. By controlling the rotation of the magnetic rotor 52 through the magnetic rotation module 51, the dyeing speed is accelerated, the dyeing time is shortened, and the time cost is saved.
[0023] A telescopic top rod 61 is installed on one side of the operating table 1, and the upper end of the telescopic top rod 61 is rotatably connected to a rotating rod 62, and the rotating rod 62 passes through the operating table 1 and is provided with a temperature sensor 6, and the detection part of the temperature sensor 6 can extend into the liquid tank 5. The temperature sensor 6 can detect the temperature of the liquid in the liquid tank 5 in real time, which is convenient for the operator to better control the temperature. When it is necessary to change the water in the liquid tank 5, the telescopic top rod 61 is started to lift the temperature sensor 6 and rotate it to one side of the liquid tank 5, which is convenient for the operator to change the water in the liquid tank 5.
[0024] A water changing pump 41 is fixedly connected to one side of the operating table 1, and the water changing pump 41 connects the water bath 4 to the external water tank through a water pipe. The water in the water bath can be changed by the water changing pump without opening the external shell, thereby improving the automation of the device.
[0025] Working principle: The operator first pulls the placement rack 7 out of the external shell 8, puts the chromosome slide into the placement rack 7, and pushes the placement rack 7 into the device. At this time, the six-axis collaborative robot 2 is started to clamp the placement rack 7 filled with chromosome slides through the electric gripper 21, and the chromosome slide is placed in the oven 3. The automatic opening and closing cover of the oven 3 is realized through the cooperation of the telescopic rod 32 and the cover plate 31, and the baking automation is realized. After the baking is completed, the chromosome slide is placed in the liquid tank 5 for dyeing by the electric gripper 21. At this time, the magnetic rotation module 51 is started to control the rotation of the magnetic rotor 52 to speed up the dyeing speed. After the dyeing is completed, it is placed in the oven 3 to dry the water droplets on the surface of the chromosome slide, and finally the placement rack 7 is pulled out from the external shell 8. This process achieves the purpose of automatic baking and dyeing integration, is simple to operate, saves manpower, solves the problems of manual single operation in each link of the production, cumbersome and laborious, and inefficient, and avoids the problem of poor production effect caused by manual operation.
[0026] The contents not described in detail in this specification belong to the prior art known to the professional and technical personnel in this field. Although the present utility model is described in detail with reference to the above embodiments, it is still possible for the technical solutions recorded in the above embodiments to be modified, or some of the technical features therein to be replaced by equivalents, and any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present utility model shall be included in the protection scope of the present utility model.
Claims
1. A chromosome baking and dyeing machine, comprising an external shell (8) and an operating table (1) placed inside the external shell (8), characterized in that: A six-axis collaborative robot (2) is fixedly connected to the internal upper top surface of the external shell (8), and an electric gripper (21) is installed on the operating end of the six-axis collaborative robot (2). An oven (3) and a water bath (4) are provided on the operating table (1), and a plurality of liquid tanks (5) for chromosome staining are installed in the water bath (4). A placement rack (7) is slidably connected to the operating table (1), and the placement rack (7) can be pulled out from the external shell (8) to replenish chromosome slides.
2. The chromosome baking and dyeing machine according to claim 1, characterized in that: A cover plate (31) is hingedly connected to one end of the oven (3); a telescopic rod (32) is rotatably connected to one side of the cover plate (31); and the other end of the telescopic rod (32) is rotatably connected to one side of the oven (3).
3. The chromosome baking and dyeing machine according to claim 1, characterized in that: A magnetic rotation module (51) is installed on the lower surface of the water bath (4), and the position and number of the magnetic rotation module (51) correspond to the liquid tank (5). A magnetic rotor (52) is arranged inside the liquid tank (5), and the magnetic rotation module (51) can control the rotation of the magnetic rotor (52).
4. The chromosome baking and dyeing machine according to claim 1, characterized in that: A telescopic top rod (61) is installed on one side of the operating table (1), and the upper end of the telescopic top rod (61) is rotatably connected to a rotating rod (62). The rotating rod (62) passes through the operating table (1) and is provided with a temperature sensor (6). The detection part of the temperature sensor (6) can extend into the liquid tank (5).
5. The chromosome baking and dyeing machine according to claim 1, characterized in that: A water exchange pump (41) is fixedly connected to one side of the operating table (1), and the water exchange pump (41) connects the water bath (4) to an external water tank via a water pipe.