Virus purification device

Abstract

The utility model relates to the technical field of pseudovirus purification devices, and discloses a virus purification device which comprises a shell and a sealing cover, and the shell is hinged to the sealing cover; the temperature control equipment is arranged in the shell; the utility model discloses a quick-locking centrifugal pump which comprises a shell, a centrifugal mechanism arranged in the shell and a locking mechanism arranged in the centrifugal mechanism, and the locking mechanism comprises a quick-locking assembly and a fixing assembly. According to the centrifugal test tube locking device, a more convenient and faster connecting and locking mode is used for further locking a test tube needing to be subjected to centrifugal operation, and when the locking operation is carried out, the device can better slide the placed test tube to the upper end and abut against and be fixed to the sealing cover, so that the stability during centrifugal operation is better guaranteed.

Description

Technical Field

[0001] The utility model relates to the technical field of pseudovirus purification devices, in particular to a virus purification device. Background Art

[0002] HPV (human papillomavirus) is a non-enveloped double-stranded circular DNA virus, whose infection may cause a variety of skin diseases, especially malignant tumors such as cervical cancer. Therefore, the development and production of HPV vaccines have great social significance.

[0003] In the process of developing and producing HPV virus, it needs to be purified to improve the accuracy of research data. However, existing equipment can use centrifugal force to crush the test tube during the purification operation. The test tube placed in the centrifugal device needs to be placed in the corresponding chamber, and then the top limiting mechanism needs to be twisted when manually taking it out to ensure the stability of the test tube during centrifugal operation. Repeated mechanical rotation is required when taking it out, which can ensure the stability of the test tube, but the operation is not convenient enough. Utility Model Content

[0004] In order to solve the technical problem that the existing purification equipment is inconvenient to take when performing purification operation, the utility model provides a virus purification device.

[0005] The utility model is implemented by the following technical solutions: a virus purification device, comprising a shell and a cover, wherein the shell and the cover are hinged;

[0006] Also includes:

[0007] a temperature control device, wherein the temperature control device is disposed in the housing;

[0008] A centrifugal mechanism is disposed in the housing.

[0009] The locking mechanism is arranged in the centrifugal mechanism, and the locking mechanism includes a quick lock component and a fixing component.

[0010] Through the above technical solution, the test tube can be quickly taken under the action of the quick lock component, thereby simplifying the operation steps, helping to improve the user experience, and under the linkage and cooperation of the quick lock component and the fixed component, it can be ensured that the test tube is stable and will not collide when the equipment is performing centrifugal operation.

[0011] As a further improvement of the above scheme, the centrifugal mechanism includes a motor installed at the bottom end of the shell, the top end of the motor is fixedly connected to a rotating shell, a mounting block is fixedly connected inside the rotating shell, and a plurality of groups of test tube slots obliquely facing inward are evenly arranged in the mounting block.

[0012] As a further improvement of the above scheme, the fixing component includes a vertical tube installed in the mounting block, a plurality of vertical grooves are evenly arranged on the lower side of the outer wall of the vertical tube, and a movable plate is vertically slidably connected in the vertical tube, a spring 1 is installed at the bottom end of the movable plate and located in the vertical tube, the bottom end of the spring 1 is fixedly connected to the mounting block, and a plurality of side rods are evenly fixedly connected to the outer wall of the movable plate.

[0013] As a further improvement of the above scheme, multiple groups of side rods are obliquely slidably connected to the outer sides with moving blocks, multiple groups of moving blocks are provided with oblique grooves on both sides, multiple groups of moving blocks are relatively horizontally slidably connected to the mounting block connection, and one side of the oblique groove is slidably connected to the side rod, and the other side is slidably connected to the oblique rod, and the outer ends of multiple groups of oblique rods are fixedly connected with push plates.

[0014] As a further improvement of the above scheme, sliding grooves are opened on the inner sides of multiple groups of test tube grooves, and multiple groups of sliding grooves are connected with inclined rods, wherein the number of test tube grooves, sliding grooves, vertical grooves, moving blocks, inclined grooves, inclined rods, push plates and side rods is the same.

[0015] Through the above technical solution, the inner rod can fully compress the spring of spring 2 by pressing down, and ensure that the push plate will not move after locking; secondly, the equipment can use the moving block to make corresponding displacement adjustments under the sliding of the inclined groove and the side rods on both sides and the inclined rod.

[0016] As a further improvement of the above scheme, the quick lock assembly includes an outer rod vertically slidably connected to the upper end of the vertical tube, an inner rod vertically slidably connected inside the outer rod, movable grooves are symmetrically provided on both sides of the inner rod, and oblique guide grooves are provided in both groups of movable grooves, sliders are slidably connected in both groups of guide grooves, and plug rods are fixedly connected to the inner sides of the two groups of sliders, the bottom end of the inner rod is abutted against spring 2, the bottom end of the spring 2 is fixedly connected to the top of the movable plate, and a sealing cover is fixedly connected to the top of the outer rod for sealing the mounting block.

[0017] As a further improvement of the above solution, the vertical tube and the outer rod are symmetrically provided with a second sliding hole and a first sliding hole, respectively, and both are slidably connected with the insertion rod.

[0018] Through the above technical solution, by pressing down the inner rod in connection with the guide groove and the slider, the insertion rod can be well driven to perform a corresponding displacement action along the sliding hole, so that the device can be better locked, and in the pressed down locking state, with the upward push of spring two, the insertion rod will be further locked and inserted in sliding hole one and sliding hole two.

[0019] Compared with the prior art, the beneficial effects of the present invention are:

[0020] The utility model utilizes a more convenient and quick connection and locking method to further lock the test tube that needs to be centrifuged. When the locking operation is performed, the device can better slide the placed test tube to the upper end and abut and fix it with the sealing cover, thereby better ensuring the stability during centrifugation. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a schematic diagram of the overall structure of a virus purification device provided in Example 1 of the utility model;

[0022] Figure 2 For this utility model Figure 1 A schematic diagram of a three-dimensional cross-sectional structure;

[0023] Figure 3 This is a schematic diagram of the internal connection state structure of the utility model;

[0024] Figure 4 For this utility model Figure 3 A schematic diagram of the structure enlargement at the center A;

[0025] Figure 5 For this utility model Figure 3 A magnified schematic diagram of the structure at point B in the middle.

[0026] Description of main symbols:

[0027] 1. Shell; 2. Sealing cover; 3. Motor; 4. Rotating shell; 5. Mounting block; 6. Test tube slot; 7. Sliding slot; 8. Vertical tube; 9. Vertical slot; 10. Movable plate; 11. Moving block; 12. Inclined slot; 13. Inclined rod; 14. Push plate; 15. Side rod; 16. Spring 1; 17. Spring 2; 18. Sealing cover; 19. Outer rod; 20. Inner rod; 21. Movable slot; 22. Guide slot; 23. Sliding block; 24. Insert rod; 25. Sliding hole 1; 26. Sliding hole 2. DETAILED DESCRIPTION

[0028] The present invention is further described below in conjunction with the accompanying drawings and specific implementation methods. It should be noted that, under the premise of no conflict, the various embodiments or technical features described below can be arbitrarily combined to form a new embodiment.

[0029] Embodiment 1:

[0030] Please combine Figure 1 , Figure 2 , Figure 3 and Figure 5 , a virus purification device of this embodiment comprises a shell 1 and a cover 2, wherein the shell 1 and the cover 2 are hinged;

[0031] Also includes:

[0032] A temperature control device, the temperature control device is arranged in the housing 1;

[0033] A centrifugal mechanism is arranged in the housing 1.

[0034] The locking mechanism is arranged in the centrifugal mechanism, and the locking mechanism comprises a quick lock component and a fixing component.

[0035] The centrifugal mechanism comprises a motor 3 mounted at the bottom of a housing 1, a rotating housing 4 is fixedly connected to the top of the motor 3, a mounting block 5 is fixedly connected inside the rotating housing 4, and a plurality of test tube slots 6 obliquely facing inward are evenly arranged inside the mounting block 5.

[0036] The fixing assembly includes a vertical tube 8 installed in the mounting block 5, a plurality of vertical grooves 9 are evenly arranged on the lower side of the outer wall of the vertical tube 8, and a movable plate 10 is vertically slidably connected in the vertical tube 8, a spring 16 is installed at the bottom end of the movable plate 10 and located in the vertical tube 8, the bottom end of the spring 16 is fixedly connected to the mounting block 5, and a plurality of side rods 15 are evenly and fixedly connected to the outer wall of the movable plate 10.

[0037] The outer sides of multiple groups of side rods 15 are all obliquely slidably connected with moving blocks 11, and oblique grooves 12 are opened on both sides of multiple groups of moving blocks 11. Multiple groups of moving blocks 11 are relatively horizontally slidably connected to the connection of the mounting block 5, and one side of the oblique groove 12 is slidably connected to the side rod 15, and the other side is slidably connected to the oblique rod 13. The outer ends of multiple groups of oblique rods 13 are fixedly connected with push plates 14.

[0038] Sliding grooves 7 are provided inside the multiple groups of test tube slots 6, and inclined rods 13 are connected to the multiple groups of sliding grooves 7, wherein the number of test tube slots 6, sliding grooves 7, vertical slots 9, moving blocks 11, inclined slots 12, inclined rods 13, push plates 14 and side rods 15 is the same.

[0039] The implementation principle of a virus purification device in the embodiment of the present application is:

[0040] When the inner rod 20 is pressed down and installed, the side rod 15 will synchronously move vertically downward along the vertical slot 9 under the pressure of the inner rod 20, and connected with the inclined slot 12 opened at the moving block 11, so that the moving block 11 will slide horizontally outward, and synchronously drive the inclined rod 13 to slide upward, and drive the push plate 14 connected to the inclined rod 13 to push the placed test tube to rise and abut against the sealing cover 18, completing further fixation. When unlocked, the test tube will descend as the push plate 14 descends.

[0041] Embodiment 2:

[0042] Combination Figure 3 and Figure 4 Based on Example 1, this embodiment is further improved in that:

[0043] The quick lock assembly includes an outer rod 19 vertically slidably connected to the upper end of the vertical tube 8, an inner rod 20 vertically slidably connected inside the outer rod 19, movable grooves 21 are symmetrically opened on both sides of the inner rod 20, and two groups of movable grooves 21 are opened in oblique guide grooves 22, sliders 23 are slidably connected in both groups of guide grooves 22, and plug rods 24 are fixedly connected to the inner sides of both groups of sliders 23, the bottom end of the inner rod 20 abuts against a spring 17, the bottom end of the spring 17 is fixedly connected to the top of the movable plate 10, and a sealing cover 18 is fixedly connected to the top of the outer rod 19 for sealing the mounting block 5.

[0044] The vertical tube 8 and the outer rod 19 are symmetrically provided with a second sliding hole 26 and a first sliding hole 25, and both are slidably connected with the insertion rod 24.

[0045] The implementation principle of this embodiment is:

[0046] First, open the hinged shell 1 and the sealing cover 2, and then press the inner rod 20 downwards, so that the slider 23 will slide with the guide groove 22 to make the insertion rod 24 retract inward, so that the insertion rod 24 will release the connection with the second slide hole 26, so that the sealing cover 18 can be quickly taken out, and then the test tube that needs to be centrifuged is placed in the test tube slot 6, and then the sealing cover 18 is placed again, and the outer rod 19 is inserted into the vertical tube 8, and the slide hole 1 25 is matched with the slide hole 26, so that when the bottom end of the inner rod 20 abuts against the spring 2 17, the inner rod 20 will be pushed vertically upward, and the insertion rod 24 will slide with the slide hole 1 25 so that the insertion rod 24 will be inserted in the slide hole 26 and locked.

[0047] Working principle:

[0048] First, open the hinged shell 1 and the sealing cover 2, and then press the inner rod 20 downwards, so that the slider 23 will slide with the guide groove 22 to make the insertion rod 24 retract inward, so that the insertion rod 24 will release the connection with the second slide hole 26, so that the sealing cover 18 can be quickly taken out, and then the test tube that needs to be centrifuged is placed in the test tube slot 6, and then the sealing cover 18 is placed again, and the outer rod 19 is inserted into the vertical tube 8, and the slide hole 1 25 is matched with the slide hole 26, so that when the bottom end of the inner rod 20 abuts against the spring 2 17, the inner rod 20 will be pushed vertically upward, and the insertion rod 24 will slide with the slide hole 1 25 so that the insertion rod 24 will be inserted in the slide hole 26 and locked.

[0049] When the inner rod 20 is pressed down and installed, the side rod 15 will be synchronously moved vertically downward along the vertical slot 9 under the pressure of the inner rod 20, and connected with the inclined slot 12 opened at the moving block 11, so that the moving block 11 will slide horizontally outward, and synchronously drive the inclined rod 13 to slide upward, and drive the push plate 14 connected to the inclined rod 13 to push the placed test tube to rise and abut against the sealing cover 18 to complete further fixation. When unlocked, the test tube will descend with the descent of the push plate 14, and then the test tube that has completed the centrifugation operation will be quickly taken away, and the next purification operation will be carried out.

[0050] The above-mentioned implementation modes are only preferred implementation modes of the present invention, and cannot be used to limit the protection scope of the present invention. Any non-substantial changes and substitutions made by technicians in this field on the basis of the present invention shall fall within the scope of protection required by the present invention.

Claims

1. A virus purification device, comprising a housing and a cover, wherein the housing and the cover are hinged; It is characterized by: Also includes: a temperature control device, wherein the temperature control device is disposed in the housing; A centrifugal mechanism is disposed in the housing. The locking mechanism is arranged in the centrifugal mechanism, and the locking mechanism includes a quick lock component and a fixing component.

2. A virus purification device according to claim 1, characterized in that: The centrifugal mechanism comprises a motor installed at the bottom end of the shell, the top end of the motor is fixedly connected with a rotating shell, a mounting block is fixedly connected inside the rotating shell, and a plurality of groups of test tube slots obliquely facing inward are evenly arranged inside the mounting block.

3. A virus purification device according to claim 1, characterized in that: The fixing assembly includes a vertical tube installed in the mounting block, a plurality of vertical grooves are evenly arranged on the lower side of the outer wall of the vertical tube, and a movable plate is vertically slidably connected in the vertical tube, a spring 1 is installed at the bottom end of the movable plate and located in the vertical tube, the bottom end of the spring 1 is fixedly connected to the mounting block, and a plurality of side rods are evenly fixedly connected to the outer wall of the movable plate.

4. A virus purification device as claimed in claim 3, characterized in that: The outer sides of the multiple groups of side rods are all obliquely slidably connected with moving blocks, and the two sides of the multiple groups of moving blocks are provided with oblique grooves. The multiple groups of moving blocks are relatively horizontally slidably connected to the connection of the mounting blocks, and one side of the oblique groove is slidably connected to the side rod, and the other side is slidably connected to the oblique rod, and the outer ends of the multiple groups of oblique rods are fixedly connected with push plates.

5. A virus purification device as claimed in claim 2, characterized in that: Sliding grooves are provided on the inner sides of the multiple groups of test tube grooves, and the multiple groups of sliding grooves are connected with inclined rods, wherein the number of test tube grooves, sliding grooves, vertical grooves, moving blocks, inclined grooves, inclined rods, push plates and side rods is the same.

6. A virus purification device according to claim 1, characterized in that: The quick lock assembly includes an outer rod vertically slidably connected to the upper end of the vertical tube, an inner rod vertically slidably connected inside the outer rod, movable grooves are symmetrically opened on both sides of the inner rod, and oblique guide grooves are opened in two groups of movable grooves, sliders are slidably connected in both groups of guide grooves, and plug rods are fixedly connected to the inner sides of the two groups of sliders, the bottom end of the inner rod abuts against spring 2, the bottom end of the spring 2 is fixedly connected to the top of the movable plate, and a sealing cover is fixedly connected to the top of the outer rod for sealing the mounting block.

7. A virus purification device according to claim 6, characterized in that: The vertical tube and the outer rod are symmetrically provided with a second sliding hole and a first sliding hole, and both are slidably connected with the insertion rod.

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