In-vitro research model for abdominal aortic aneurysm endoluminal repair post-operation type II endoleakage

Abstract

The utility model discloses an abdominal aortic aneurysm intracavitary repair post-operation II-type endoleakage in-vitro research model, which comprises an aorta, an abdominal aortic aneurysm is arranged below the aorta, the left side of the abdominal aortic aneurysm is communicated with an arterial arch through a lower mesenteric artery, the arterial arch is communicated with one end of an upper mesenteric artery, and the other end of the upper mesenteric artery is communicated with a lower mesenteric artery. A first flow speed regulator is arranged between the arterial arch and the superior mesenteric artery, the other end of the superior mesenteric artery is communicated with an aorta above the abdominal aortic aneurysm, the lower portion of the aorta is communicated with the upper portions of the right iliac artery and the left iliac artery, and the lower portions of the right iliac artery and the left iliac artery are communicated with one end of a connecting artery. The other end of the connecting artery is communicated with the waist artery and one end of the abdominal aorta inflow tube, the other end of the waist artery is communicated with the right side of the abdominal aortic aneurysm, and the waist artery is provided with a drip cup and a second flow speed regulator. According to the utility model, related prevention, treatment and research of type II internal leakage after subsequent abdominal aortic aneurysm intracavitary repair are facilitated.

Description

Technical Field

[0001] The utility model relates to the technical field of type II endoleak in vitro research models, in particular to an in vitro research model for type II endoleak after endovascular repair of an abdominal aortic aneurysm. Background Art

[0002] Abdominal aortic aneurysm (AAA) is one of the common diseases in vascular surgery, which is defined as localized dilatation of the abdominal aorta ≥50% of the normal arterial diameter. Endovascular repair (EVAR) is still the first choice for the treatment of AAA. However, 30%-50% of patients with AAA have abnormal anatomical conditions. The proportion of EVAR for AAA with abnormal anatomical conditions is increasing. However, these AAA with abnormal anatomical conditions are more likely to cause various complications after EVAR, especially the incidence of complications such as endoleak is higher. Among them, type II endoleak (T2EL) is the most common type of endoleak after EVAR.

[0003] Type II endoleak refers to the reverse blood supply from branch vessels on the aneurysm body to the aneurysm cavity after EVAR surgery, which leads to further enlargement of the aneurysm cavity. Previous studies have shown that the incidence of type II endoleak is between 10.2% and 29.0%. The main problem vessels for type II endoleak are the inferior mesenteric artery or lumbar artery, etc. However, there is currently a lack of corresponding models for in vitro research on type II endoleak.

[0004] Therefore, an in vitro research model of type II endoleak after endovascular repair of abdominal aortic aneurysm was proposed to address the above issues. Utility Model Content

[0005] The utility model aims to provide an in vitro research model of type II endoleak after endovascular repair of abdominal aortic aneurysm, comprising an aorta, an abdominal aortic aneurysm is arranged below the aorta, a stent is arranged inside the abdominal aortic aneurysm, and the stent is closely attached to the inner wall of the abdominal aortic aneurysm, the left side of the abdominal aortic aneurysm is connected with the arterial arch through the inferior mesenteric artery, the arterial arch is connected with one end of the superior mesenteric artery, a flow regulator 1 is arranged between the arterial arch and the superior mesenteric artery, the other end of the superior mesenteric artery is connected with the aorta above the abdominal aortic aneurysm, the lower part of the aorta is respectively connected with the right iliac artery and the upper part of the left iliac artery, the lower part of the right iliac artery and the left iliac artery are connected with one end of the connecting artery, the other end of the connecting artery is respectively connected with the lumbar artery and one end of the abdominal aortic inflow tube, the other end of the lumbar artery is connected with the right side of the abdominal aortic aneurysm, a drip pot and a flow regulator 2 are respectively arranged on the lumbar artery, the other end of the abdominal aortic inflow tube is connected with the upper part of the aorta, and a peristaltic pump is arranged on the abdominal aortic inflow tube.

[0006] Compared with the prior art, the utility model has the following beneficial effects: the utility model makes a type II endoleak in a model, observes the blood flow in the drip pot on the model, determines whether a type II endoleak has occurred, and after determining that a type II endoleak has occurred, adjusts the speeds of flow regulator 1 and flow regulator 2, thereby adjusting the blood flow speed of the type II endoleak, thereby facilitating subsequent treatment and mechanism research of aneurysm cavities related to type II endoleak. BRIEF DESCRIPTION OF THE DRAWINGS

[0007] Figure 1 It is a structural schematic diagram of the utility model.

[0008] The reference numerals and names in the figures are as follows:

[0009] 1. Abdominal aortic inflow tube; 2. Aorta; 3. Superior mesenteric artery; 4. Flow regulator 1; 5. Arterial arch; 6. Inferior mesenteric artery; 7. Abdominal aortic aneurysm; 8. Right renal artery; 9. Left renal artery; 10. Right iliac artery; 11. Left iliac artery; 12. Lumbar artery; 13. Drip pot; 14. Flow regulator 2; 15. Peristaltic pump; 16. Connecting artery; 17. Covered stent. DETAILED DESCRIPTION

[0010] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0011] As attached Figure 1As shown, the utility model provides an in vitro research model of type II endoleak after endovascular repair of abdominal aortic aneurysm, comprising an aorta 2, an abdominal aortic aneurysm 7 is arranged below the aorta 2, a stent is arranged inside the abdominal aortic aneurysm, and the stent is closely attached to the inner wall of the abdominal aortic aneurysm, the left side of the abdominal aortic aneurysm 7 is connected to the aortic arch 5 through the inferior mesenteric artery 6, the aortic arch 5 is connected to one end of the superior mesenteric artery 3, a flow regulator 4 is arranged between the aortic arch 5 and the superior mesenteric artery 3, and the other end of the superior mesenteric artery 3 is connected to the aorta 2 above the abdominal aortic aneurysm 7 The lower part of the aorta 2 is connected with the right iliac artery 10 and the upper part of the left iliac artery 11 respectively; the lower parts of the right iliac artery 10 and the left iliac artery 11 are connected with one end of a connecting artery 16; the other end of the connecting artery 16 is connected with the lumbar artery 12 and one end of an abdominal aortic inflow tube 1 respectively; the other end of the lumbar artery 12 is connected with the right side of an abdominal aortic aneurysm 7; a drip pot 13 and a flow regulator 14 are respectively provided on the lumbar artery 12; the other end of the abdominal aortic inflow tube 1 is connected with the upper part of the aorta 2; and a peristaltic pump 15 is provided on the abdominal aortic inflow tube 1.

[0012] Specifically, the left side of the aorta 2 above the abdominal aortic aneurysm 7 is connected to the right renal artery 8 , and the right side of the aorta 2 above the abdominal aortic aneurysm 7 is connected to the left renal artery 9 .

[0013] Specifically, the right iliac artery 10 and the left iliac artery 11 are connected to the connecting artery 16 in a Y shape at their lower parts.

[0014] Specifically, the connecting artery 16 is connected to the lumbar artery 12 and the abdominal aorta inflow tube 1 in a Y shape.

[0015] Specifically, the stent 17 is a covered stent that simulates implantation in the human body, and its function is to completely isolate the aneurysm from the blood circulation in the blood vessels, and eliminate the pressure of the blood flow in the blood vessels on the aneurysm, thereby achieving the purpose of treating abdominal aortic aneurysm.

[0016] Working principle: To simulate and study the prevention of T2EL during EVAR of abdominal aortic aneurysm, after blood is injected into the model, the blood in the model flows from the abdominal aorta inflow tube 1 to the abdominal aortic aneurysm 7 under the driving action of the peristaltic pump 15. By adjusting the speed of the flow speed regulator 1 4 and the flow speed regulator 2 14, the blood flows through the superior mesenteric artery 3, the arterial arch 5, and the inferior mesenteric artery 6 after the intracavitary isolation treatment of the covered stent in the aneurysm, which is used to simulate the circulation of the superior mesenteric artery, the inferior mesenteric artery and the riolan arch of the human body, and continues to supply blood to the aneurysm cavity outside the stent, and flows out from the lumbar artery 12 to the connecting pipe 16 to simulate the lumbar artery of the human body, so that the aneurysm cavity and the blood circulation cannot be completely separated, that is, type II internal leakage is formed;

[0017] On the model, the blood flow in the drip pot 13 is observed to determine whether type II endoleak has occurred. After the occurrence of type II endoleak is determined, the speed of flow regulator 1 4 and flow regulator 2 14 are adjusted to adjust the blood flow speed of type II endoleak. At the same time, the treatment and mechanism of the aneurysm cavity related to type II endoleak are studied through the superior mesenteric artery 3, the aortic arch 5, and the inferior mesenteric artery 6. For example, coil embolization, thrombin injection, and stent 17 are placed to achieve thrombotic occlusion of the aneurysm cavity to achieve the purpose of treating or preventing type II endoleak, so as to observe whether the coagulant can achieve the effect of preventing or treating type II endoleak. At the same time, vascular smooth muscle cells or endothelial cells can be implanted on the wall of the abdominal aortic aneurysm 7 of the model to study the effect of embolic materials on the function of endothelial cells and smooth muscle cells. By detecting the degree of blood flow, hemodynamics can also be studied to further intuitively reflect the hemodynamics of type II endoleak after abdominal aortic aneurysm EVAR surgery.

[0018] In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "two ends", "one end", "the other end" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as a limitation on the present invention. In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0019] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "provided with", "connected", etc. should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

Claims

1. An in vitro research model for type II endoleak after endovascular repair of abdominal aortic aneurysm, comprising an aorta (2), characterized in that: An abdominal aortic aneurysm (7) is arranged below the aorta (2), a covered stent (17) is arranged inside the abdominal aortic aneurysm (7), and the covered stent (17) is closely attached to the inner wall of the abdominal aortic aneurysm (7), the left side of the abdominal aortic aneurysm (7) is connected to the aortic arch (5) through the inferior mesenteric artery (6), the aortic arch (5) is connected to one end of the superior mesenteric artery (3), a flow regulator (4) is arranged between the aortic arch (5) and the superior mesenteric artery (3), the other end of the superior mesenteric artery (3) is connected to the aorta (2) above the abdominal aortic aneurysm (7), and the lower part of the aorta (2) is connected to the right and left sides of the aorta (2) respectively. The lateral iliac artery (10) and the left iliac artery (11) are connected at the top, and the right iliac artery (10) and the left iliac artery (11) are connected at the bottom with one end of the connecting artery (16). The other end of the connecting artery (16) is respectively connected with the lumbar artery (12) and one end of the abdominal aorta inflow tube (1). The other end of the lumbar artery (12) is connected with the right side of the abdominal aortic aneurysm (7). The lumbar artery (12) is respectively provided with a drip pot (13) and a second flow regulator (14). The other end of the abdominal aorta inflow tube (1) is connected with the top of the aorta (2). A peristaltic pump (15) is provided on the abdominal aorta inflow tube (1).

2. The in vitro research model of type II endoleak after endovascular repair of abdominal aortic aneurysm according to claim 1, characterized in that: The left side of the aorta (2) above the abdominal aortic aneurysm (7) is connected to the right renal artery (8), and the right side of the aorta (2) above the abdominal aortic aneurysm (7) is connected to the left renal artery (9).

3. The in vitro research model of type II endoleak after endovascular repair of abdominal aortic aneurysm according to claim 1, characterized in that: The lower parts of the right iliac artery (10) and the left iliac artery (11) are connected to the connecting artery (16) in a Y shape.

4. The in vitro research model of type II endoleak after endovascular repair of abdominal aortic aneurysm according to claim 1, characterized in that: The connecting artery (16) is connected to the lumbar artery (12) and the abdominal aorta inflow tube (1) in a Y shape.

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