Blood purification pipeline system

Abstract

The utility model discloses a blood purification pipeline system, and relates to the technical field of medical instruments. According to the blood purification pipeline system, an artery pipeline assembly and a liquid medicine input pipeline assembly are both arranged on an integrated disc, a plurality of pipeline installation positions are arranged in the circumferential direction of the integrated disc at intervals, and pipeline guide positions are arranged below the pipeline installation positions. The artery pipeline assembly is fixed to the pipeline installation position, the liquid medicine input pipeline assembly is fixed through the pipeline installation position and the pipeline guide position, and during installation, only one end of the artery pipeline assembly needs to be connected with the filter assembly; one end of the liquid medicine input pipeline assembly is connected with a liquid medicine source, the other end of the liquid medicine input pipeline assembly is connected with the artery pipeline assembly or the vein pipeline assembly, the vein pipeline assembly is connected with the filter assembly, medical staff do not need to connect and install all the pipeline assemblies, installation steps are simplified, operation is easy and convenient, and operation can be conducted by inexperienced staff. And the workload and the learning cost of medical personnel are reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of medical equipment, in particular to a blood purification pipeline system. Background Art

[0002] Continuous renal replacement therapy (CRRT), also known as continuous blood purification (CBP), is a new blood purification method. Initially used to treat acute renal failure (ARF), after continuous research and exploration, its scope of use has been expanded to severe trauma, sepsis, multiple organ failure, severe heart failure, acute respiratory failure, etc. Recently, it has developed into an auxiliary treatment for artificial liver support system, neuroimmune system, cell purification and other technologies, becoming an important treatment method for various critical diseases.

[0003] Usually, blood purification equipment is used for continuous renal replacement therapy. During treatment, the blood purification equipment uses a blood purification pipeline system to connect with the human body's arteriovenous blood vessels, and introduces the blood in the human arterial blood vessels into the dialyzer, perfusion device, plasma separator, plasma component separator, filter and other filter components in the blood purification equipment. Different types of filter components can remove pathogens, water, toxic substances or metabolic waste in the blood, and then the purified blood is returned to the human body through the veins. Due to the large number of pipelines in the blood purification pipeline system and the cumbersome installation, clinical operations require experienced medical personnel to complete smoothly, which increases the workload and learning costs of medical staff. Utility Model Content

[0004] The utility model aims to provide a blood purification pipeline system, the pipeline components of the blood purification pipeline system have high integration, simplified installation steps of the pipeline components, easier operation, and reduced workload and learning costs for medical staff.

[0005] To achieve this purpose, the utility model adopts the following technical solutions:

[0006] A blood purification pipeline system is used to connect to a blood purification device, wherein the blood purification device includes a filter assembly, and the blood purification pipeline system includes:

[0007] An arterial line assembly, one end of which is connected to the human body, and the other end of which is connected to the filter assembly, and the arterial line assembly is used to lead blood from the human body to the filter assembly;

[0008] A venous line assembly, one end of which is connected to the filter assembly and the other end of which is connected to the human body, and is used to return the blood purified by the filter assembly to the human body;

[0009] A liquid medicine input pipeline assembly, one end of which is connected to a liquid medicine source, and the other end of which is connected to the arterial pipeline assembly or the venous pipeline assembly;

[0010] An integrated disk is provided with a plurality of pipeline installation positions and a plurality of pipeline guide positions, the plurality of pipeline installation positions are arranged at intervals along the circumference of the integrated disk, the pipeline guide positions are arranged below the pipeline installation positions, the arterial pipeline assembly is fixed to the pipeline installation positions, and the liquid medicine input pipeline assembly is fixed through the pipeline installation positions and the pipeline guide positions.

[0011] As an optional solution of the blood purification pipeline system, the pipeline installation position includes two installation holes arranged at intervals, and the two ends of the pipeline component fixed to the pipeline installation position pass through the two installation holes respectively.

[0012] As an optional solution of the blood purification pipeline system, the pipeline guide position includes a plurality of guide grooves, and the pipeline assembly fixed to the pipeline guide position is guided and fixed by the guide grooves.

[0013] As an optional solution of the blood purification pipeline system, each pipeline installation position is provided with a position mark of a corresponding type of pipeline component.

[0014] As an optional solution of the blood purification pipeline system, the drug liquid input pipeline assembly includes a front liquid replenishment pipeline assembly, which is connected to the arterial pipeline assembly and is arranged at the pipeline installation position for replenishing drug liquid.

[0015] As an optional scheme of the blood purification pipeline system, the drug liquid input pipeline assembly also includes a first anticoagulant drug liquid pipeline assembly and a second anticoagulant drug liquid pipeline assembly, the first anticoagulant drug liquid pipeline assembly can be connected to the venous pipeline assembly for replenishing the first anticoagulant drug liquid; the second anticoagulant drug liquid pipeline assembly can be connected to the arterial pipeline assembly for replenishing the second anticoagulant drug liquid; the first anticoagulant drug liquid pipeline assembly and the second anticoagulant drug liquid pipeline assembly are both arranged at the pipeline guide position; the first anticoagulant drug liquid pipeline assembly and the second anticoagulant drug liquid pipeline assembly are used selectively.

[0016] As an optional solution of the blood purification pipeline system, a first three-way one-way valve is provided at the end of the venous pipeline assembly close to the connection with the human body, and the first anticoagulant liquid pipeline assembly is connected to the first three-way one-way valve, and the first three-way one-way valve is used for one-way conduction of the first anticoagulant liquid pipeline assembly to the venous pipeline assembly.

[0017] As an optional scheme of the blood purification pipeline system, the venous pipeline assembly includes a venous pot, a diverter fluid is provided in the venous pot, the diverter fluid divides the inner cavity of the venous pot into a first cavity, a second cavity and a third cavity, the diverter fluid includes a buffer part and a bearing part, the venous pot is provided with a liquid inlet, a liquid outlet and a liquid replenishing port, the liquid outlet is provided at one end of the venous pot, the first cavity is formed between the liquid outlet and the bearing part, the second cavity is formed between the bearing part and the buffer part, the liquid inlet is communicated with the first cavity or the second cavity, the third cavity is formed between the buffer part and the other end of the venous pot, the liquid replenishing port is communicated with the third cavity, the buffer part is used to buffer the impact force of the liquid replenished from the liquid replenishing port entering the second cavity, the bearing part is connected to the inner wall of the venous pot, and the bearing part and the buffer part are both provided with a connecting structure to connect the first cavity, the second cavity and the third cavity.

[0018] As an optional solution of the blood purification pipeline system, the venous pot is configured to be in a shuttle shape.

[0019] As an optional solution of the blood purification pipeline system, the connecting structure includes a connecting ring, the buffer portion is configured to be conical, the top of the conical buffer portion is configured to face the third cavity, and the connecting ring is formed between the bottom and the inner wall of the venous pot, and the liquid entering the third cavity through the liquid replenishing inlet flows from the top of the buffer portion to the bottom to the connecting ring.

[0020] As an optional solution of the blood purification pipeline system, the connecting structure also includes a connecting hole, the bearing portion is provided with inner grooves at intervals along the outer periphery of the bearing portion, a connecting hole is formed between the inner grooves and the inner wall of the venous pot, and the convex portions formed between adjacent inner grooves are connected to the inner wall of the venous pot.

[0021] As an optional solution of the blood purification pipeline system, the venous pipeline assembly also includes a venous pot liquid inlet pipe, the venous pot liquid inlet pipe is connected to the liquid inlet, and a first warming pot is arranged on the venous pot liquid inlet pipe.

[0022] As an optional solution of the blood purification piping system, the blood purification piping system also includes a dialysate piping assembly, which is arranged at the piping installation position, one end of the dialysate piping assembly is connected to the dialysate source, and the other end is connected to the filter assembly.

[0023] As an optional solution of the blood purification pipeline system, the dialysate pipeline assembly is provided with two dialysate branch pipelines away from the end connected to the dialysate source, one of the dialysate branch pipelines is connected to the filter assembly, and the other dialysate branch pipeline is used to supplement the therapeutic liquid.

[0024] As an optional scheme of the blood purification piping system, the blood purification piping system also includes a replacement fluid piping assembly, which is arranged at the pipeline installation position, one end of the replacement fluid piping assembly is connected to the replacement fluid source, and the other end of the replacement fluid piping assembly is connected to the arterial piping assembly and / or the venous piping assembly.

[0025] As an optional solution of the blood purification pipeline system, a second warming pot is further provided on the dialysate pipeline assembly, and a third warming pot is further provided on the replacement fluid pipeline assembly.

[0026] As an optional scheme of the blood purification pipeline system, the replacement fluid pipeline assembly includes a first replacement fluid pipeline assembly and a second replacement fluid pipeline assembly, the first replacement fluid pipeline assembly can be selectively connected to the arterial pipeline assembly or the venous pipeline assembly, and the second replacement fluid pipeline assembly is connected to the arterial pipeline assembly.

[0027] As an optional solution of the blood purification pipeline system, the blood purification pipeline system also includes a mixed fluid infusion pipeline assembly, which is arranged at the pipeline installation position, one end of the mixed fluid infusion pipeline assembly is connected to the fluid infusion source, and the other end can be selectively connected to the arterial pipeline assembly or the venous pipeline assembly.

[0028] As an optional scheme of the blood purification pipeline system, the blood purification equipment also includes two pipeline selectors, and two pipeline selector fixing positions are provided on the integrated disk, and the two pipeline selectors are respectively fixed on the two pipeline selector fixing positions, and the first replacement fluid pipeline assembly includes a front replacement fluid branch pipeline and a rear replacement fluid branch pipeline, the front replacement fluid branch pipeline is connected to the arterial pipeline assembly, and the rear replacement fluid branch pipeline is connected to the venous pipeline assembly, and one of the pipeline selectors can selectively open the front replacement fluid branch pipeline or the rear replacement fluid branch pipeline; the mixed fluid infusion pipeline assembly includes a front fluid infusion branch pipeline and a rear fluid infusion branch pipeline, the front fluid infusion branch pipeline is connected to the arterial pipeline assembly, and the rear fluid infusion branch pipeline is connected to the venous pipeline assembly, and the other pipeline selector can selectively open the front fluid infusion branch pipeline or the rear fluid infusion branch pipeline.

[0029] As an optional solution of the blood purification pipeline system, the blood purification pipeline system also includes a waste liquid bag and a waste liquid pipeline assembly, the waste liquid pipeline assembly is arranged at the pipeline installation position, one end of the waste liquid pipeline assembly is connected to the filter assembly, and the other end is connected to the waste liquid bag.

[0030] As an optional solution of the blood purification pipeline system, the blood purification pipeline system also includes a pre-flushing pipeline assembly, the pre-flushing pipeline assembly includes a pre-flushing main pipeline and a plurality of pre-flushing branch pipelines connected to the pre-flushing main pipeline, the pre-flushing main pipeline is connected to a pre-flushing liquid source, the plurality of pre-flushing branch pipelines are respectively connected to the arterial pipeline assembly, the liquid medicine input pipeline assembly and the mixed fluid infusion pipeline assembly, and the venous pipeline assembly is connected to the waste liquid bag;

[0031] Alternatively, the priming main pipeline is connected to a priming liquid source, and the plurality of priming branch pipelines are respectively connected to the arterial pipeline assembly, the liquid medicine input pipeline assembly, the mixed fluid infusion pipeline assembly and the venous pipeline assembly.

[0032] Beneficial effects of the utility model:

[0033] The blood purification pipeline system provided by the utility model is provided with an arterial pipeline assembly and a liquid medicine input pipeline assembly on an integrated disk, and a plurality of pipeline installation positions are arranged at intervals in the circumference of the integrated disk, and a pipeline guide position is arranged below the pipeline installation position. The arterial pipeline assembly is fixed to the pipeline installation position, and the liquid medicine input pipeline assembly is fixed by the pipeline installation position and the pipeline guide position. When installing the blood purification pipeline system, it is only necessary to connect one end of the arterial pipeline assembly to the filter assembly; connect one end of the liquid medicine input pipeline assembly to the liquid medicine source, and connect the other end to the arterial pipeline assembly or the venous pipeline assembly, and connect the venous pipeline assembly to the filter assembly. The blood purification pipeline system realizes the integration and orderly fixation of each pipeline assembly through the integrated disk. During clinical operation, it is only necessary to fix the integrated disk on the blood purification device, and then connect each pipeline assembly to the blood purification device and the human body one by one. Medical staff do not need to connect and install each pipeline assembly, which greatly simplifies the installation steps, is easy to operate, and can be operated by inexperienced personnel, reducing the workload and learning cost of medical staff.

[0034] The blood purification pipeline system arranges a flow divider in the venous pot in the venous pipeline assembly, so that the liquid replenished through the liquid replenishing inlet enters the third cavity, is buffered by the buffer part, and then enters the second cavity through the connecting structure. The arrangement of the buffer part reduces the impact of the replenished liquid on the blood, so that the replenished liquid flows evenly and dispersedly onto the blood and forms a liquid layer, effectively isolating air and blood, and greatly reducing the risk of blood clotting in the venous pot.

[0035] The blood purification pipeline system, the replacement fluid pipeline assembly includes a first replacement fluid pipeline assembly that can be selectively connected to the arterial pipeline assembly or the venous pipeline assembly and a second replacement fluid pipeline assembly connected to the arterial pipeline assembly, which can not only meet the front and back simultaneous replacement of the replacement fluid in the continuous venous hemofiltration treatment mode; but also meet the front and back simultaneous replacement of the replacement fluid in the continuous venous hemodiafiltration treatment mode. At the same time, the mixed fluid infusion pipeline assembly can be selectively connected to the arterial pipeline assembly or the venous pipeline assembly. When the replacement fluid base fluid is needed in the treatment mode used in the clinic, sodium bicarbonate injection needs to be added, which can meet the requirements of the same side and the same proportion of the sodium bicarbonate injection injection and the replacement fluid base fluid according to the drug instructions of the replacement fluid base fluid and the clinical expert recommendation. Further, by setting a pipeline selector fixing position on the integrated disk, it is used to fix the pipeline selector on the blood purification device, and the pipeline selector can control the replacement fluid pipeline assembly to be connected to the arterial pipeline assembly or the venous pipeline assembly and the mixed fluid infusion pipeline assembly to be connected to the arterial pipeline assembly or the venous pipeline assembly.

[0036] The blood purification pipeline system, the pre-flushing pipeline assembly includes a pre-flushing main pipeline and multiple pre-flushing branch pipelines connected to the pre-flushing main pipeline, the multiple pre-flushing branch pipelines are respectively connected to the arterial pipeline assembly, the anticoagulant pipeline assembly and the mixed fluid infusion pipeline assembly, and the venous pipeline assembly is connected to the waste liquid bag, so that one bag of pre-flushing liquid can complete the pre-flushing of multiple pipeline assemblies, and the pre-flushing liquid is collected into the waste liquid bag through the venous pipeline assembly, which simplifies the pre-flushing operation steps and greatly improves the pre-flushing efficiency of the pipeline assembly. BRIEF DESCRIPTION OF THE DRAWINGS

[0037] Figure 1 This is a schematic diagram of the structure of the blood purification pipeline system provided by the first embodiment of the utility model;

[0038] Figure 2 It is a schematic diagram of the structure of the integrated disk provided in the first embodiment of the utility model;

[0039] Figure 3 It is a top view of the integrated disk provided in the first embodiment of the utility model;

[0040] Figure 4 It is a bottom view of the integrated disk provided in the first embodiment of the utility model;

[0041] Figure 5 This is a schematic diagram of the structure of the intravenous kettle provided in the first embodiment of the utility model;

[0042] Figure 6 is a cross-sectional view of a venous pot provided in Embodiment 1 of the utility model;

[0043] Figure 7 It is an exploded view of the intravenous pot provided in the first embodiment of the utility model;

[0044] Figure 8 It is a structural schematic diagram of the blood purification pipeline system provided in the second embodiment of the present utility model.

[0045] In the figure:

[0046] 100, clamp; 200, Luer connector; 300, plug; 400, needle; 500, Hansen connector;

[0047] 1. Arterial pipeline assembly; 11. Arterial pump tube; 12. Arterial main pipeline; 13. Arterial branch pipeline; 14. First four-way connector; 15. First pressure sensor; 16. Second pressure sensor; 17. First three-way connector; 18. Second three-way connector;

[0048] 2. Liquid medicine input pipeline assembly; 21. Front fluid infusion pipeline assembly; 22. Second anticoagulant liquid medicine pipeline assembly; 23. First anticoagulant liquid medicine pipeline assembly;

[0049] 3. Venous line assembly; 31. Venous pot; 311. Liquid inlet; 312. Liquid outlet; 313. Liquid replenishment inlet; 314. Diverter; 3141. Buffer; 3142. Bearing part; 3143. Connecting part; 315. First cavity; 316. Second cavity; 317. Third cavity; 318. Connecting port; 319. Filter element; 32. Venous pot liquid inlet pipe; 321. First warming pot; 33. Liquid replenishment pipeline; 34. Venous pot liquid outlet pipe; 341. First three-way one-way valve; 35. Venous pot branch pipeline; 36. Venous pressure sensor;

[0050] 4. Waste liquid pipeline assembly; 41. Waste liquid outlet branch; 42. Waste liquid bypass; 43. Third pressure sensor;

[0051] 5. Integrated disk; 51. Pipeline installation position; 511. Installation hole; 512. Positioning slot; 513. First emergency hole; 52. Guide slot; 53. Position mark; 54. Pipeline selector fixing position; 541. Perforation; 542. Second emergency hole;

[0052] 6. Dialysis fluid pipeline assembly; 61. Second warming pot; 62. Dialysis fluid branch pipeline;

[0053] 71. First replacement fluid pipeline assembly; 711. Front replacement fluid branch pipeline; 712. Rear replacement fluid branch pipeline; 713. Third warming pot; 72. Second replacement fluid pipeline assembly;

[0054] 8. Mixed fluid infusion pipeline assembly; 81. Front fluid infusion branch pipeline; 82. Rear fluid infusion branch pipeline;

[0055] 9. Waste liquid bag; 91. Waste liquid inlet branch;

[0056] 10. Pre-flushing pipeline assembly; 101. Pre-flushing main pipeline; 102. Pre-flushing branch pipeline. DETAILED DESCRIPTION

[0057] In order to make the technical problems solved by the present invention, the technical solutions adopted and the technical effects achieved more clearly, the technical solutions of the present invention are further explained below with reference to the accompanying drawings and through specific implementation methods.

[0058] In the description of the present invention, unless otherwise clearly specified and limited, the terms "connected", "connected", and "fixed" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0059] Embodiment 1:

[0060] like Figure 1 As shown, the blood purification pipeline system provided in this embodiment is used to connect the blood purification equipment to the human body, so as to lead the blood in the human body to the filter component in the blood purification equipment, remove the pathogens, moisture, toxic substances or metabolic wastes in the blood through the filter component, and then return the blood purified by the filter component to the human body. According to the analysis of the blood purification treatment principle and clinical actual use, the blood purification treatment mode includes a single circulation system treatment mode and a dual circulation system treatment mode. Due to the differences in the principles of different treatment modes, the required pipeline structures are different, and different types of supporting pipeline systems are required to complete the treatment.

[0061] The blood purification pipeline system provided in this embodiment is used in the treatment mode of a single circulation system, and can meet the treatment needs of blood perfusion and blood perfusion-related treatments.

[0062] The blood purification pipeline system includes an arterial pipeline component 1, a venous pipeline component 3, a liquid medicine input pipeline component 2 and an integrated disk 5. The arterial pipeline component 1 and the liquid medicine input pipeline component 2 are both arranged on the integrated disk 5. Specifically, the integrated disk 5 is provided with a plurality of pipeline installation positions 51 and a plurality of pipeline guide positions. The plurality of pipeline installation positions 51 are arranged at intervals along the circumference of the integrated disk 5. The pipeline guide position is arranged below the pipeline installation position 51. The arterial pipeline component 1 is fixed to the pipeline installation position 51, and the liquid medicine input pipeline component 2 is fixed through the pipeline installation position 51 and the pipeline guide position. The integrated disk 5 realizes the integration and orderly fixation of each pipeline component. During clinical operation, it is only necessary to fix the integrated disk 5 on the blood purification device, and then connect each pipeline component to the blood purification device one by one. There is no need for medical staff to connect and install each pipeline component, which greatly simplifies the installation steps, is easy to operate, and can be operated by inexperienced personnel, reducing the workload and learning cost of medical staff.

[0063] Specifically, Figure 2-Figure 4 As shown, the integrated disk 5 includes a bottom plate and a side plate arranged around the bottom plate, and a plurality of pipeline installation positions 51 are arranged on the side plate, and a plurality of pipeline components are installed in the pipeline installation positions 51 in a one-to-one correspondence, and each pipeline installation position 51 is provided with a position mark 53 of a corresponding type of pipeline component. In this embodiment, the position mark 53 includes graphic symbols such as "△", "□", and "◎", and different graphic symbols represent different types of pipeline components. When medical personnel connect the pipeline component to the blood purification equipment and the human body, they only need to identify the type of the pipeline component according to the position mark 53, which reduces the risk of incorrect installation of different types of pipeline components.

[0064] The pipeline installation position 51 includes two installation holes 511 arranged at intervals, and the two ends of the pipeline assembly fixed to the pipeline installation position 51 respectively pass through the two installation holes 511. The installation holes 511 are arranged on the side plate, and a positioning groove 512 is also arranged between the two installation holes 511. The blood purification device also includes pump heads of various pipeline assemblies, and the positioning groove 512 is used to position the pump heads.

[0065] Furthermore, the pipeline installation position 51 also includes a first emergency hole 513, which is arranged on the bottom plate and corresponds to the central hole of the pump head. When the blood purification device is powered off, a special wrench can be used to pass through the first emergency hole 513 and cooperate with the central hole of the pump head to drive the pump head to rotate.

[0066] Specifically, one end of the arterial pipeline assembly 1 is connected to the human body, and the other end is connected to the filter assembly. The arterial pipeline assembly 1 is used to lead the blood in the human body to the filter assembly. The filter assembly includes filters such as a perfusion device, a plasma separator, a plasma component separator, and a filter. When performing blood perfusion and blood perfusion-related treatments, the arterial pipeline assembly 1 is connected to the perfusion device. The arterial pipeline assembly 1 includes an arterial pipeline, various accessories, a joint or a plug 300, etc. The arterial pipeline includes an arterial pump tube 11 and an arterial main pipeline 12. When the integrated disk 5 is fixed on the blood purification device, the pump heads of each pipeline assembly are respectively placed in the positioning groove 512 of the pipeline installation position 51 where each pipeline assembly is located. The arterial pump tube 11 is arranged around the circumference of the pump head of the arterial pipeline assembly 1. The rotation of the pump head of the arterial pipeline assembly 1 drives the liquid in the arterial pump tube 11 to flow, providing power for the liquid flow in the arterial pipeline assembly 1. The two ends of the arterial pump tube 11 are respectively connected to one end of the two mounting holes 511, and the other ends of the two mounting holes 511 are respectively connected to the arterial main line 12. The arterial main line 12 is arranged outside the side panel, so that the length of the arterial main line 12 is not limited, which makes it easier to connect the arterial main line 12 with the blood purification equipment and the human body.

[0067] One end of the venous line assembly 3 is connected to the filter assembly, and the other end is connected to the human body, for returning the blood purified by the filter assembly to the human body. The venous line assembly 3 is arranged on one side of the integrated disk 5, one end is connected to the outlet of the filter assembly, and the other end is connected to the human body.

[0068] The integrated disk 5 also includes a reinforcing plate, which is arranged in the circumference of the side plate and perpendicular to the side plate. The mounting hole 511 extends from the side plate to the end of the reinforcing plate away from the side plate. In order to ensure the reliability of the connection between the arterial pump tube 11 and the arterial main line 12, the mounting hole 511 needs to have a certain extension length. By setting the reinforcing plate perpendicular to the side plate, the mounting hole 511 extends from the side plate to the width direction of the reinforcing plate.

[0069] Specifically, the liquid medicine input pipeline assembly 2 includes a front liquid infusion pipeline assembly 21, which is connected to the arterial pipeline assembly 1, and the front liquid infusion pipeline assembly 21 is arranged at the pipeline installation position 51, for replenishing liquid medicine. The front liquid infusion pipeline assembly 21 can be flexibly applied to the anticoagulation system, and can also be used for infusion independently. When the front liquid infusion pipeline assembly 21 is applied to the anticoagulation system, the liquid medicine is citric acid. The connection method of the front liquid infusion pipeline assembly 21 and the pipeline installation position 51 is the same as the connection method of the arterial pipeline assembly 1 and the pipeline installation position 51, which will not be repeated here.

[0070] The liquid medicine input pipeline assembly 2 also includes a first anticoagulant liquid medicine pipeline assembly 23 and a second anticoagulant liquid medicine pipeline assembly 22. The first anticoagulant liquid medicine pipeline assembly 23 can be connected to the venous pipeline assembly 3 to replenish the first anticoagulant liquid medicine; the second anticoagulant liquid medicine pipeline assembly 22 can be connected to the arterial pipeline assembly 1 to replenish the second anticoagulant liquid medicine; the first anticoagulant liquid medicine pipeline assembly 23 and the second anticoagulant liquid medicine pipeline assembly 22 are both arranged at the pipeline guide position; the first anticoagulant liquid medicine pipeline assembly 23 and the second anticoagulant liquid medicine pipeline assembly 22 can be used selectively. The first anticoagulant liquid medicine pipeline assembly 23 and the venous pipeline assembly 3 are of separate design, and the separate design facilitates the discharge of gas in the first anticoagulant liquid medicine pipeline assembly 23.

[0071] Specifically, a plurality of pipeline guide positions are arranged at intervals below the reinforcing plate, and each pipeline guide position includes a plurality of guide grooves 52, and the pipeline assembly fixed to the pipeline guide position is guided and fixed by the guide grooves 52. The guide grooves 52 are arranged as semicircular grooves with the notches facing upward and / or downward, so as to facilitate the fixing of the first anticoagulant liquid medicine pipeline assembly 23 and the second anticoagulant liquid medicine pipeline assembly 22.

[0072] Furthermore, a first three-way one-way valve 341 is provided at the end of the venous pipeline assembly 3 close to the connection with the human body, and the first anticoagulant liquid pipeline assembly 23 is connected to the first three-way one-way valve 341, and the first three-way one-way valve 341 is used for one-way conduction from the first anticoagulant liquid pipeline assembly 23 to the venous pipeline assembly 3. By setting the first three-way one-way valve 341 to connect the first anticoagulant liquid pipeline assembly 23, only the liquid in the first anticoagulant liquid pipeline assembly 23 is allowed to flow into the venous pipeline assembly 3, and the liquid in the venous pipeline assembly 3 cannot flow out through the first three-way one-way valve 341, thereby ensuring safety during actual use. A one-way valve is provided at the end of the second anticoagulant liquid pipeline assembly 22 connected to the second anticoagulant liquid source, and the one-way valve can block the liquid in the arterial pipeline assembly 1 from flowing to the second anticoagulant liquid pipeline assembly 22.

[0073] In this embodiment, the first anticoagulant liquid medicine includes calcium or anticoagulant antagonist, and the second anticoagulant liquid medicine includes heparin. The first anticoagulant liquid medicine pipeline assembly 23 and the second anticoagulant liquid medicine pipeline assembly 22 share a pump head, which can selectively drive the liquid medicine in the first anticoagulant liquid medicine pipeline assembly 23 or the liquid medicine in the second anticoagulant liquid medicine pipeline assembly 22. Citric acid is supplemented in the front infusion pipeline assembly 21 and used in combination with the calcium in the first anticoagulant liquid medicine pipeline assembly 23 for anticoagulation. The heparin in the second anticoagulant liquid medicine pipeline assembly 22 can be used alone for anticoagulation.

[0074] The arterial main line 12 connected to the human body is provided with a first three-way joint 17 and a second three-way joint 18. One end of the front infusion pipeline assembly 21 is connected to the arterial main line 12 connected to the arterial blood vessels of the human body through the first three-way joint 17, and the other end is connected to a citric acid source. The front infusion pipeline assembly 21 is used to supplement citric acid. The arterial main line 12 connected to the filter assembly is provided with a first four-way joint 14. One end of the second anticoagulant liquid pipeline assembly 22 is connected to the arterial main line 12 connected to the filter assembly, and the other end is connected to a heparin source for supplementing heparin. The second three-way joint 18 and another interface of the first four-way joint 14 are also connected to an arterial branch line 13, and the arterial branch line 13 is used to connect other pipelines. The pipeline guide position includes a plurality of guide grooves 52, and the first anticoagulant liquid pipeline assembly 23 and the second anticoagulant liquid pipeline assembly 22 are both guided and fixed by the guide grooves 52. The front infusion pipeline can also be supplemented with other anticoagulants.

[0075] Furthermore, a first pressure sensor 15 is provided on the arterial main line 12 connected to the arterial blood vessels of the human body, and a second pressure sensor 16 is provided on the arterial main line 12 connected to the filter assembly. Both the first pressure sensor 15 and the second pressure sensor 16 are membrane pressure sensors, which use a closed pressure monitoring method to reduce the contact between the liquid and the air in the arterial line assembly 1, reduce the occurrence of coagulation, and reduce the risk of air entering the arterial line assembly 1. Of course, in other embodiments, the first pressure sensor 15 and the second pressure sensor 16 may also be ordinary pressure sensors.

[0076] In the blood purification pipeline system used for hemoperfusion therapy in the prior art, an arterial pot is provided in the arterial pipeline assembly 1. Usually, blood is in contact with air in the arterial pot, which is prone to generate bubbles and has the risk of causing air embolism and coagulation. In the blood purification pipeline system provided in this embodiment, the arterial pot design is cancelled in the arterial pipeline assembly 1, which reduces the overall blood volume in the arterial pipeline assembly 1, reduces the chance of blood contact with air, and reduces the risk of blood coagulation.

[0077] Meanwhile, the capacity of the venous pot 31 in the venous tubing assembly 3 in the prior art is too large, and the unreasonable design easily causes blood shock and forms bubbles, and there is dead space when the liquid flows in the venous pot 31, which easily causes blood clotting.

[0078] In order to solve the dead space of the intravenous pot 31 and reduce the risk of blood clotting, as Figure 1 , Figure 5-Figure 7 As shown, the venous line assembly 3 provided in this embodiment includes a venous pot 31, in which a diverter 314 and a filter element 319 are provided. The diverter 314 divides the inner cavity of the venous pot 31 into a first cavity 315, a second cavity 316 and a third cavity 317. The diverter 314 includes a buffer portion 3141 and a bearing portion 3142. The venous pot 31 is provided with a liquid inlet 311, a liquid outlet 312 and a liquid replenishing port 313. The liquid outlet 312 is provided at one end of the venous pot 31, and a first cavity 315 is formed between the liquid outlet 312 and the bearing portion 3142. The filter element 319 is provided in the first cavity 315 for filtering the blood entering the human body. A second cavity 316 is formed between the bearing part 3142 and the buffer part 3141, the liquid inlet 311 is connected to the first cavity 315 or the second cavity 316, a third cavity 317 is formed between the buffer part 3141 and the other end of the venous pot 31, the liquid replenishing port 313 is connected to the third cavity 317, the buffer part 3141 is used to buffer the impact force of the liquid replenished from the liquid replenishing port 313 entering the second cavity 316, the bearing part 3142 is connected to the inner wall of the venous pot 31, and the bearing part 3142 and the buffer part 3141 are both provided with a connecting structure to connect the first cavity 315, the second cavity 316 and the third cavity 317. When performing blood purification treatment, blood enters the second cavity 316 from the liquid inlet 311, and the second cavity 316 is located between the first cavity 315 and the third cavity 317, and there is no dead angle therein, and blood flows fully in the second cavity 316. The replenishing liquid enters the third cavity 317 through the liquid replenishing inlet 313, is buffered by the buffer part 3141, and then enters the second cavity 316 through the connecting structure. The setting of the buffer part 3141 reduces the impact of the replenishing liquid on the blood, so that the replenishing liquid flows evenly and dispersedly onto the blood in the second cavity 316 and forms a liquid layer, which effectively isolates the air and blood, and greatly reduces the risk of blood coagulation in the venous pot 31.

[0079] In this embodiment, the liquid inlet 311 is connected to the second cavity 316. In other embodiments, the liquid inlet 311 may also be connected to the first cavity 315. In this arrangement, blood directly enters the first cavity 315 through the liquid inlet 311, which reduces the flow resistance of blood and avoids the formation of dead space.

[0080] The venous line assembly 3 also includes a venous pot inlet pipe 32, a liquid replenishment pipe 33 and a venous pot outlet pipe 34. One end of the venous pot inlet pipe 32 is connected to the liquid inlet 311, and the other end is connected to the outlet of the filter assembly to introduce the blood purified by the filter assembly into the second cavity 316 of the venous pot 31. One end of the liquid replenishment pipe 33 is connected to the liquid replenishment port 313, and the other end is connected to the liquid replenishment source, so that the liquid in the liquid replenishment source enters the third cavity 317 through the liquid replenishment pipe 33. One end of the venous pot outlet pipe 34 is connected to the liquid outlet 312, and the other end is connected to the human body's venous blood vessels to return the blood passing through the venous pot 31 to the human body. A first warming pot 321 is provided on the venous pot inlet pipe 32, which is used to heat and keep the blood entering the venous pot 31 to improve the comfort of the patient. The intravenous pot liquid inlet pipe 32, the liquid replenishment pipeline 33 and the intravenous pot liquid outlet pipe 34 are also provided with accessories such as a clamp 100, a Luer interface 200 and a plug 300. The switch of the pipeline is controlled by the clamp 100, and the plug 300 is provided at the end of the intravenous pot liquid inlet pipe 32 away from the liquid inlet 311, the end of the liquid replenishment pipeline 33 away from the liquid replenishment port 313 and the end of the intravenous pot liquid outlet pipe 34 away from the liquid outlet 312. The Luer interface 200 is used to connect components such as a syringe, an infusion set or a sensor. When the intravenous pot liquid inlet pipe 32 is not connected to the outlet of the filter assembly, the liquid replenishment pipeline 33 is not connected to the liquid replenishment source and the intravenous pot liquid outlet pipe 34 is not connected to the venous blood vessel, the plug 300 is used to block the intravenous pot liquid inlet pipe 32 to prevent external dust or impurities from entering the pipeline.

[0081] Two connecting ports 318 are also provided at one end of the venous pot 31 away from the liquid outlet 312. The two connecting ports 318 are each connected to a venous pot branch pipeline 35. A venous pressure sensor 36 is connected to one of the venous pot branch pipelines 35. The venous pressure sensor 36 is used to monitor the pressure in the venous pot 31, and then judge the liquid flow in the venous pot 31 according to the pressure in the venous pot 31; the other venous pot branch pipeline 35 is used to connect a syringe or an infusion pump. Each venous pot branch pipeline 35 is also provided with a clamp 100, a Luer interface 200 and a plug 300.

[0082] Specifically, the flow divider 314 also includes a connecting portion 3143, and the sides where the buffer portion 3141 and the bearing portion 3142 are close to each other are both set as planes. The connecting portion 3143 is used to connect the buffer portion 3141 and the bearing portion 3142. The connecting portion 3143 is set as a columnar body, and the two ends of the connecting portion 3143 of the columnar body are smoothly connected to the centers of the two planes respectively, thereby reducing the dead space in the second cavity 316, and the connecting portion 3143 occupies a smaller volume of the second cavity 316, which makes it easier for blood to flow fully in the second cavity 316.

[0083] Furthermore, the venous pot 31 is configured in a shuttle shape. The circumference diameters of the two ends of the shuttle-shaped venous pot 31 body are smaller, and the circumference diameter in the middle is larger, so that the blood entering the second cavity 316 from the liquid inlet 311 can flow fully in the second cavity 316 without forming a dead cavity.

[0084] Specifically, the connecting structure includes a connecting ring, the buffer portion 3141 is configured to be conical, the top of the conical buffer portion 3141 is configured to face the third cavity 317, and a connecting ring is formed between the bottom and the inner wall of the venous pot 31. The liquid entering the third cavity 317 through the liquid replenishing port 313 flows from the top of the buffer portion 3141 to the bottom to the connecting ring. Since the third cavity 317 gradually shrinks from the direction close to the buffer portion 3141 to the direction away from the buffer portion 3141, the liquid replenishing port 313 is arranged at a position of the third cavity 317 away from the buffer portion 3141. The replenishing liquid entering the third cavity 317 through the liquid replenishing port 313 slowly flows down through the conical surface of the conical buffer portion 3141, and disperses along the circumferential direction of the buffer portion 3141 during the downward flow, until it flows to the connecting ring and enters the second cavity 316. The kinetic energy of the replenishing liquid is smaller than when it flows downward in the vertical direction, and is evenly dispersed on the blood to form a liquid layer, which effectively separates the air and the blood, thereby reducing the impact on the blood in the second cavity 316, reducing the formation of bubbles, and further reducing the risk of blood coagulation.

[0085] Of course, in other embodiments, the buffer portion 3141 may also be configured as a spherical body or other buffer structures.

[0086] Furthermore, the connecting structure also includes connecting holes. The bearing part 3142 is provided with inner grooves at intervals along the outer periphery of the bearing part 3142. Connecting holes are formed between the inner grooves and the inner wall of the venous pot 31. The convex parts formed between adjacent inner grooves are connected to the inner wall of the venous pot 31. The flow divider 314 is fixed in the accommodating cavity through the bearing part 3142. In order to realize the connection between the flow divider 314 and the body of the venous pot 31 and to allow the liquid to flow into the first cavity 315 through the second cavity 316, the convex parts on the outer periphery of the bearing part 3142 are connected to the inner wall of the body of the venous pot 31 by interference fit or other methods such as gluing, and the liquid flows to the first cavity 315 through the connecting holes. The multiple connecting holes around the bearing part 3142 allow the replacement fluid and blood to flow into the first cavity 315 through the multiple connecting holes, thereby preventing dead space and further reducing the risk of blood coagulation. Of course, in other embodiments, a connecting hole may be directly provided on the plane of the bearing portion 3142 , and the outer circumference of the bearing portion 3142 is cooperatively connected with the inner wall of the venous pot 31 .

[0087] In this embodiment, one end of the bearing portion 3142 close to the first cavity 315 is configured as a conical structure, and the conical structure can guide the liquid entering the first cavity 315 to flow gradually from the circumference of the bearing portion 3142 to a position close to the center and downward to the filter element 319. The filter element 319 is also configured as a cone, and the small end of the conical filter element 319 is configured close to the small end of the conical structure, which can prevent blood from accumulating in the middle of the bearing portion 3142 and causing the flow rate to be too slow to form a blood clot.

[0088] In order to facilitate the installation of the flow divider 314 and the filter 319, the intravenous pot 31 is set as a split structure, including a first pot body and a second pot body. The end of the first pot body away from the second pot body is provided with a liquid outlet 312, and the first pot body and the second pot body are connected by snapping. The liquid inlet 311 and the liquid replenishing port 313 are both provided on the second protective body. When installing the flow divider 314, the filter 319 is first inserted into the first pot body and snapped into the first pot body, and then the flow divider 314 is inserted into the second pot body, and then the first pot body and the second pot body are snapped together, and finally glue is applied at the connection between the first pot body and the second pot body to make the two bodies bonded as one.

[0089] The blood purification pipeline system provided in this embodiment is provided with a diverter 314 in the venous pot 31 in the venous pipeline assembly 3, so that the liquid replenished through the liquid replenishing inlet 313 enters the third cavity 317, and then enters the second cavity 316 through the connecting structure after being buffered by the buffer part 3141. The setting of the buffer part 3141 reduces the impact of the replenished liquid on the blood, so that the replenished liquid flows evenly and dispersedly on the blood and forms a liquid layer, effectively isolating the air and blood, and greatly reducing the risk of blood coagulation in the venous pot 31. In addition, by providing a first heating pot 321 on the venous pot inlet pipe 32 connected to the liquid inlet 311 of the venous pot 31 in the venous pipeline assembly 3, the blood returned to the human body is heated and kept warm, which increases the comfort of the patient.

[0090] Furthermore, the blood purification pipeline system provided in this embodiment also includes a waste liquid bag 9 and a pre-flushing pipeline assembly 10, the pre-flushing pipeline assembly 10 includes a pre-flushing main pipeline 101 and a plurality of pre-flushing branch pipelines 102 connected to the pre-flushing main pipeline 101, the pre-flushing main pipeline 101 is connected to the pre-flushing liquid source, the plurality of pre-flushing branch pipelines 102 are respectively connected to the arterial pipeline assembly 1 and the anticoagulant pipeline assembly 2, and the end of the venous pipeline assembly 3 connected to the human body's venous blood vessels is connected to the waste liquid bag 9. Two waste liquid inlet branches 91 are provided on the waste liquid bag 9, and the two waste liquid inlet branches 91 are both provided with a clamp 100, a Luer interface 200 and a plug 300. In this embodiment, one of the waste liquid inlet branches 91 is connected to one end of the venous pipeline assembly 3 connected to the human body, and the other waste liquid inlet branch 91 is blocked by the plug 300. After the blood purification pipeline system is connected to the blood purification equipment, before being connected to the human body's arteriovenous blood vessels, each pipeline component needs to be pre-flushed. By setting up multiple pre-flushing branch pipelines 102, only one bag of pre-flushing liquid is needed to be connected to the pre-flushing main pipeline 101. Multiple pre-flushing branch pipelines 102 are respectively connected to the arterial pipeline component 1 and the pre-flushing pipeline component 21. The pre-flushing liquid passes through the arterial pipeline component 1 and the pre-flushing pipeline component 21 and enters the second anticoagulant liquid pipeline component 22 and the filter component, and then enters the venous pipeline component 3 and the first anticoagulant liquid pipeline component 23 for flushing. Finally, the pre-flushing liquid flows into the waste liquid bag 9 through the end of the venous pipeline component 3 connected to the human body, which simplifies the pre-flushing operation steps and greatly improves the pre-flushing efficiency of the pipeline components.

[0091] Embodiment 2:

[0092] like Figure 8 As shown, this embodiment provides a blood purification pipeline system for the treatment mode of the dual circulation system, which can not only meet the treatment needs of blood perfusion and blood perfusion-related treatments, but also meet the treatment needs of continuous venous hemofiltration, continuous venous hemodialysis, continuous venous hemodiafiltration, slow continuous ultrafiltration, single plasma exchange therapy, repeated albumin dialysis, single albumin dialysis and plasma diafiltration, etc., which require the combination of blood circuit and dialysis circulation.

[0093] The blood purification pipeline system provided in this embodiment not only includes the various pipeline components in the blood purification pipeline system provided in Example 1, but the venous pot inlet pipe 32 in the blood purification pipeline system provided in this embodiment is not provided with a first heating pot 321. In addition, the blood purification pipeline system provided in this embodiment also includes a dialysate pipeline assembly 6, a replacement fluid pipeline assembly, a mixed infusion pipeline assembly 8 and a waste liquid pipeline assembly 4, and the dialysate pipeline assembly 6, the replacement fluid pipeline assembly, the mixed infusion pipeline assembly 8 and the waste liquid pipeline assembly 4 are all arranged at the pipeline installation position 51 of the circumference of the integrated disk 5, and one end of the dialysate pipeline assembly 6 is connected to the dialysate source, and the other end is connected to the filter assembly. The dialysate pipeline assembly 6 is also provided with a second heating pot 61, and the second heating pot 61 heats the dialysate and enters the filter assembly, and the filter assembly is based on the principles of diffusion, convection and adsorption to achieve the effect of blood purification. One end of the replacement fluid pipeline assembly is connected to the replacement fluid source, and the other end of the replacement fluid pipeline assembly is connected to the arterial pipeline assembly 1 and / or the venous pipeline assembly 3. A third warming pot 713 is also provided on the replacement fluid pipeline assembly. The replacement fluid enters the blood after being heated by the third warming pot 713 to maintain the electrolyte and acid-base balance in the blood. One end of the mixed fluid infusion pipeline assembly 8 is connected to the fluid infusion source, and the other end can be selectively connected to the arterial pipeline assembly 1 or the venous pipeline assembly 3. The fluid infusion source can be sodium bicarbonate injection. When the replacement fluid used in the blood purification treatment process is the finished replacement fluid base fluid, the mixed fluid infusion pipeline assembly 8 can realize the same side and proportion input of sodium bicarbonate injection and the replacement fluid base fluid, meeting the treatment mode of continuous venovenous hemodiafiltration. One end of the waste fluid pipeline assembly 4 is connected to the filter assembly, and the other end is connected to the waste fluid bag 9.

[0094] Furthermore, the dialysate pipeline assembly 6 is provided with two dialysate branch pipelines 62 at one end away from the dialysate source, one of which is connected to the filter assembly via a Hansen connector 500, and the other dialysate branch pipeline 62 replenishes the therapeutic liquid in the dialysate in real time according to clinical needs. In this embodiment, the dialysate branch pipeline 62 can be used to replenish sodium bicarbonate injection, which is convenient for clinical use when sodium bicarbonate injection is added to the replacement fluid base fluid to make the dialysate.

[0095] Specifically, the replacement fluid pipeline assembly includes a first replacement fluid pipeline assembly 71 and a second replacement fluid pipeline assembly 72. The first replacement fluid pipeline assembly 71 can be selectively connected to the arterial pipeline assembly 1 or the venous pipeline assembly 3, and the second replacement fluid pipeline assembly 72 is connected to the arterial pipeline assembly 1. The first replacement fluid pipeline assembly 71 can selectively replenish the replacement fluid into the arterial pipeline assembly 1 or replenish the replacement fluid into the venous pipeline assembly 3, and the second replacement fluid pipeline assembly 72 is used to replenish the replacement fluid into the arterial pipeline assembly 1. Such a setting can not only meet the front and back simultaneous replacement of the replacement fluid in the continuous venous hemofiltration treatment mode; but also meet the front and back simultaneous replacement of the replacement fluid in the continuous venous hemodiafiltration treatment mode. At the same time, the mixed infusion pipeline assembly 8 can be selectively connected to the arterial pipeline assembly 1 or the venous pipeline assembly 3. When the replacement fluid base liquid is needed in the clinical treatment mode, sodium bicarbonate injection needs to be added. It can meet the requirements of the drug instructions of the replacement fluid base liquid and the recommendations of clinical experts, and the sodium bicarbonate injection and the replacement fluid base liquid are added on the same side and in the same proportion.

[0096] Specifically, combined Figure 2-Figure 4 , Figure 8 As shown, the blood purification device also includes two pipeline selectors, and two pipeline selector fixing positions 54 are provided on the integrated disk 5. The two pipeline selectors are respectively fixed on the two pipeline selector fixing positions 54. The first replacement fluid pipeline assembly 71 includes a front replacement fluid branch pipeline 711 and a rear replacement fluid branch pipeline 712. The front replacement fluid branch pipeline 711 is connected to the arterial pipeline assembly 1, and the rear replacement fluid branch pipeline 712 is connected to the venous pipeline assembly 3. One of the pipeline selectors can selectively open the front replacement fluid branch pipeline 711 or the rear replacement fluid branch pipeline 712; the mixed fluid infusion pipeline assembly 8 includes a front fluid infusion branch pipeline 81 and a rear fluid infusion branch pipeline 82. The front fluid infusion branch pipeline 81 is connected to the arterial pipeline assembly 1, and the rear fluid infusion branch pipeline 82 is connected to the venous pipeline assembly 3. The other pipeline selector can selectively open the front fluid infusion branch pipeline 81 or the rear fluid infusion branch pipeline 82.

[0097] Furthermore, by setting a pipeline selector fixing position 54 on the integrated disk 5 to fix the pipeline selector on the blood purification device, the pipeline selector can control the connection between the replacement fluid pipeline assembly and the arterial pipeline assembly 1 or the venous pipeline assembly 3 and the connection between the mixed fluid infusion pipeline assembly 8 and the arterial pipeline assembly 1 or the venous pipeline assembly 3.

[0098] Specifically, the pipeline selector fixing position 54 includes a mounting groove, and the pipeline selector is installed in the mounting groove. Two through holes 541 are arranged at intervals on the opposite side walls of the mounting groove, wherein the two through holes 541 on one side wall and the two through holes 541 on the other side wall are arranged one by one. The pipeline selector includes a selection rod and two card plates, and the selection rod is located between the two card plates. The pipeline selector selectively opens the front replacement fluid branch pipeline 711 and the rear replacement fluid branch pipeline 712. The front replacement fluid branch pipeline 711 and the rear replacement fluid branch pipeline 712 are opened. The pipeline 712 passes through the two perforations 541 on one side wall and then passes out from the two perforations 541 on the other side wall. The front replacement fluid branch pipeline 711 is located between one of the card plates and the selection rod, and the rear replacement fluid branch pipeline 712 is located between the other card plate and the selection rod. The selection rod can selectively move toward one of the two card plates to close one of the front replacement fluid branch pipeline 711 and the rear replacement fluid branch pipeline 712, so that the other branch pipeline is opened. The connection method of the front replacement fluid branch pipeline 81 and the rear replacement fluid branch pipeline 82 with the pipeline selector and the principle of the control switch are the same as the connection method of the front replacement fluid branch pipeline 711 and the rear replacement fluid branch pipeline 712 with the pipeline selector and the principle of the control switch, which will not be repeated here.

[0099] A second emergency hole 542 is also provided at the bottom of the mounting groove. When the blood purification device is powered off, the position of the selection rod can be adjusted through the second emergency hole 542.

[0100] The blood purification pipeline system provided in this embodiment also includes a pre-flushing pipeline assembly 10, which includes a pre-flushing main pipeline 101 and a plurality of pre-flushing branch pipelines 102 connected to the pre-flushing main pipeline 101. Before treatment, the pre-flushing main pipeline 101 is connected to the pre-flushing liquid source, and the plurality of pre-flushing branch pipelines 102 are respectively connected to the arterial pipeline assembly 1, the liquid medicine input pipeline assembly 2, and the mixed liquid infusion pipeline assembly 8. The end of the venous pipeline assembly 3 connected to the human body is connected to the waste liquid bag 9 for pre-flushing of each pipeline assembly. When the tube is circulated, the pre-flushing main pipeline 101 is connected to the pre-flushing liquid source, and the plurality of pre-flushing branch pipelines 102 are respectively connected to the arterial pipeline assembly 1, the liquid medicine input pipeline assembly 2, the mixed liquid infusion pipeline assembly 8, and the venous pipeline assembly 3. With such a setting, when circulating the tube, it is only necessary to connect the venous pipeline assembly 3 to one of the pre-flushing branch pipelines 102, which is more convenient for circulating the tube.

[0101] In this embodiment, four priming branch lines 102 are provided. When priming each pipeline assembly, one of the priming branch lines 102 is closed by the clamp 100, and the other three priming branch lines 102 are respectively connected to the arterial pipeline assembly 1, the pre-infusion pipeline assembly 21, and the mixed infusion pipeline assembly 8. When the tube is circulated, the four priming branch lines 102 are respectively connected to the arterial pipeline assembly 1, the pre-infusion pipeline assembly 21, the mixed infusion pipeline assembly 8, and the venous pipeline assembly 3.

[0102] In this embodiment, the two waste liquid inlet branches 91 on the waste liquid bag 9, one of which is connected to the end of the venous pipeline assembly 3 connected to the human body, and the other waste liquid inlet branch 91 is connected to the end of the waste liquid pipeline assembly 4 away from the filter assembly. After the blood purification pipeline system is connected to the blood purification equipment, each pipeline assembly needs to be pre-flushed before treatment. By setting a plurality of pre-flushing branch pipelines 102, only one bag of pre-flushing liquid is needed to be connected to the pre-flushing main pipeline 101, and the plurality of pre-flushing branch pipelines 102 are respectively connected to the arterial pipeline assembly 1, the pre-flushing pipeline assembly 21 and the mixed fluid replenishment pipeline assembly 8. The pre-flushing liquid passes through the arterial pipeline assembly 1, the pre-flushing pipeline assembly 21 and the mixed fluid replenishment pipeline assembly 8 and enters the filter assembly and then enters the venous pipeline assembly 3 for flushing. Finally, the pre-flushing liquid flows into the waste liquid bag 9 through the end of the venous pipeline assembly 3 connected to the human body and the waste liquid pipeline assembly 4, which simplifies the pre-flushing operation steps and greatly improves the pre-flushing efficiency of the pipeline assembly. It should be noted that the dialysate pipeline assembly 6 and the replacement fluid pipeline assembly need to be pre-flushed with a pre-flushing liquid. The first anticoagulant liquid pipeline assembly 23 and the second anticoagulant liquid pipeline assembly 22 are pre-flushed separately when needed.

[0103] In this embodiment, one end of the waste liquid pipeline assembly 4 connected to the waste liquid bag 9 is provided with two waste liquid outlet branches 41 and a waste liquid bypass 42. The two waste liquid outlet branches 41 can be connected to a waste liquid bag 9 respectively, or only one waste liquid outlet branch 41 can be connected to the waste liquid bag 9, and the other waste liquid outlet branch 41 is blocked by a plug 300. The waste liquid bypass 42 is used to connect the waste liquid discharged from other pipelines. The other end of the waste liquid pipeline assembly 4 can be connected to the filter assembly through a Hansen connector 500.

[0104] On the integrated disk 5 provided in this embodiment, seven pipeline installation positions 51 are provided, and three pipeline installation positions 51 are respectively provided on the two side panels extending along the length direction of the integrated disk 5, wherein the three pipeline installation positions 51 on one side panel are respectively installed with the front fluid infusion pipeline assembly 21, the first replacement fluid pipeline assembly 71 and the dialysate pipeline assembly 6, and the three pipeline installation positions 51 on the other side panel are respectively installed with the waste fluid pipeline assembly 4, the mixed fluid infusion pipeline assembly 8 and the second replacement fluid pipeline assembly 72, wherein the front fluid infusion pipeline assembly 21 and the waste fluid pipeline assembly 4 are arranged opposite to each other, the first replacement fluid pipeline assembly 71 and the mixed fluid infusion pipeline assembly 8 are arranged opposite to each other, and the dialysate pipeline assembly 6 and the second replacement fluid pipeline assembly 72 are arranged opposite to each other. A pipeline installation position 51 is provided on one side panel extending in the width direction of the integrated disk 5, and the pipeline installation position 51 is used to install the arterial pipeline assembly 1; a pipeline selector fixing position 54 is provided on the other side panel, and the pipeline selector fixing position 54 is used to install a pipeline selector for controlling the first replacement fluid pipeline assembly 71 to selectively connect with the arterial pipeline assembly 1 or the venous pipeline assembly 3. Another pipeline selector fixing position 54 is provided on the outer side of the side panel where the pipeline installation position 51 for installing the mixed infusion pipeline assembly 8 is installed, and the pipeline selector fixing position 54 is used to install a pipeline selector for controlling the mixed infusion pipeline assembly 8 to selectively connect with the arterial pipeline assembly 1 or the venous pipeline assembly 3. The first anticoagulant drug liquid pipeline assembly 23 and the second anticoagulant drug liquid pipeline assembly 22 are arranged in the guide groove 52 on the outer periphery of the side panel on the side where the pipeline installation position 51 of the front infusion pipeline assembly 21 is located, so as to guide the first anticoagulant drug liquid pipeline assembly 23 to one end to be connected with the venous pipeline assembly 3, and the venous pot outlet pipe 34 of the venous pipeline assembly 3 is provided with a first three-way one-way valve 341, and the venous pot outlet pipe 34 is connected to the first anticoagulant drug liquid pipeline assembly 23 through the first three-way one-way valve 341, and the second anticoagulant drug liquid pipeline assembly 22 is connected to the arterial main pipeline 12 connected to the arterial pipeline assembly 1 and the filter assembly through the first three-way connector 17.

[0105] Further, in the blood purification pipeline system provided in the present embodiment, pressure sensors are provided in both the arterial pipeline assembly 1 and the waste liquid pipeline assembly 4. In the present embodiment, a first pressure sensor 15 is provided on the arterial main pipeline 12 connected to the arterial blood vessels of the human body, a second pressure sensor 16 is provided on the arterial main pipeline 12 connected to the filter assembly, and a third pressure sensor 43 is provided at one end of the waste liquid pipeline assembly 4 connected to the dialysis bypass of the filter assembly. The first pressure sensor 15 and the second pressure sensor 16 are both membrane pressure sensors, and the membrane pressure sensor adopts a closed pressure monitoring method, which reduces the contact between the liquid and the air in the arterial pipeline assembly 1, reduces the occurrence of coagulation, and reduces the risk of air entering the arterial pipeline assembly 1. The third pressure sensor 43 is also a membrane pressure sensor, and the third pressure sensor 43 is used to monitor the pressure in the waste liquid pipeline assembly 4, reduces the contact between the liquid and the air in the waste liquid pipeline assembly 4, and reduces the risk of air entering the dialyzer.

[0106] It should be noted that both ends of each pipeline assembly are provided with accessories such as a clamp 100, a Luer interface 200, a plug 300 or a needle 400. The user can use the clamp 100 to control the switch of the pipeline, connect the filter assembly through the Luer interface 200, block the pipeline through the plug 300, or connect to the fluid replenishment source through the needle 400 as needed, which will not be repeated here.

[0107] The above contents are only preferred embodiments of the present invention. For ordinary technicians in this field, according to the concept of the present invention, there will be changes in the specific implementation methods and application scopes. The contents of this specification should not be understood as limiting the present invention.

Claims

1. A blood purification pipeline system, used to connect to a blood purification device, wherein the blood purification device includes a filter assembly, characterized in that: The blood purification pipeline system comprises: An arterial line assembly (1), one end of the arterial line assembly (1) is connected to a human body, and the other end is connected to the filter assembly, and the arterial line assembly (1) is used to lead blood in a human body to the filter assembly; A venous line assembly (3), one end of which is connected to the filter assembly, and the other end of which is connected to the human body, and is used to return the blood purified by the filter assembly to the human body; A liquid medicine input pipeline assembly (2), one end of which is connected to a liquid medicine source, and the other end of which is connected to the arterial pipeline assembly (1) or the venous pipeline assembly (3); An integrated disk (5) is provided with a plurality of pipeline installation positions (51) and a plurality of pipeline guide positions, the plurality of pipeline installation positions (51) are arranged at intervals along the circumference of the integrated disk (5), the pipeline guide positions are arranged below the pipeline installation positions (51), the arterial pipeline assembly (1) is fixed to the pipeline installation position (51), and the liquid medicine input pipeline assembly (2) is fixed via the pipeline installation position (51) and the pipeline guide position.

2. The blood purification pipeline system according to claim 1, characterized in that: The pipeline installation position (51) comprises two installation holes (511) arranged at intervals, and two ends of the pipeline assembly fixed to the pipeline installation position (51) pass through the two installation holes (511) respectively.

3. The blood purification pipeline system according to claim 1, characterized in that: The pipeline guiding position comprises a plurality of guiding grooves (52), and the pipeline assembly fixed to the pipeline guiding position is guided and fixed by the guiding grooves (52).

4. The blood purification pipeline system according to claim 1, characterized in that: Each pipeline installation position (51) is provided with a position mark (53) of a corresponding type of pipeline component.

5. The blood purification pipeline system according to claim 1, characterized in that: The liquid medicine input pipeline assembly (2) comprises a front liquid replenishment pipeline assembly (21), the front liquid replenishment pipeline assembly (21) is connected to the arterial pipeline assembly (1), and the front liquid replenishment pipeline assembly (21) is arranged at the pipeline installation position (51) and is used to replenish liquid medicine.

6. The blood purification pipeline system according to claim 5, characterized in that: The drug liquid input pipeline assembly (2) also includes a first anticoagulant drug liquid pipeline assembly (23) and a second anticoagulant drug liquid pipeline assembly (22); the first anticoagulant drug liquid pipeline assembly (23) can be connected to the venous pipeline assembly (3) to replenish the first anticoagulant drug liquid; the second anticoagulant drug liquid pipeline assembly (22) can be connected to the arterial pipeline assembly (1) to replenish the second anticoagulant drug liquid; the first anticoagulant drug liquid pipeline assembly (23) and the second anticoagulant drug liquid pipeline assembly (22) are both arranged at the pipeline guide position; the first anticoagulant drug liquid pipeline assembly (23) and the second anticoagulant drug liquid pipeline assembly (22) are used selectively.

7. The blood purification pipeline system according to claim 6, characterized in that: The end of the venous pipeline assembly (3) close to the connection with the human body is provided with a first three-way one-way valve (341), and the first anticoagulant liquid pipeline assembly (23) is connected to the first three-way one-way valve (341). The first three-way one-way valve (341) is used for one-way conduction of the first anticoagulant liquid pipeline assembly (23) to the venous pipeline assembly (3).

8. The blood purification pipeline system according to claim 1, characterized in that: The venous line assembly (3) comprises a venous pot (31), a fluid divider (314) is arranged in the venous pot (31), the fluid divider (314) divides the inner cavity of the venous pot (31) into a first cavity (315), a second cavity (316) and a third cavity (317), the fluid divider (314) comprises a buffer portion (3141) and a bearing portion (3142), the venous pot (31) is provided with a liquid inlet (311), a liquid outlet (312) and a liquid replenishing port (313), the liquid outlet (312) is arranged at one end of the venous pot (31), the first cavity (315) is formed between the liquid outlet (312) and the bearing portion (3142), and a liquid replenishing port (313) is formed between the bearing portion (3142) and the buffer portion (3141). The second cavity (316), the liquid inlet (311) is connected to the first cavity (315) or the second cavity (316), the third cavity (317) is formed between the buffer portion (3141) and the other end of the venous pot (31), the liquid replenishing port (313) is connected to the third cavity (317), the buffer portion (3141) is used to buffer the impact force of the liquid replenished from the liquid replenishing port (313) entering the second cavity (316), the bearing portion (3142) is connected to the inner wall of the venous pot (31), and the bearing portion (3142) and the buffer portion (3141) are both provided with a connecting structure to connect the first cavity (315), the second cavity (316) and the third cavity (317).

9. The blood purification pipeline system according to claim 8, characterized in that: The venous pot (31) is configured in a shuttle shape.

10. The blood purification pipeline system according to claim 9, characterized in that: The connecting structure includes a connecting ring, the buffer portion (3141) is configured to be conical, the top of the conical buffer portion (3141) is configured to face the third cavity (317), and the connecting ring is formed between the bottom and the inner wall of the venous pot (31), and the liquid entering the third cavity (317) through the liquid replenishing port (313) flows from the top of the buffer portion (3141) to the bottom to the connecting ring.

11. The blood purification pipeline system according to claim 9, characterized in that: The connecting structure also includes a connecting hole, the bearing portion (3142) is provided with inner grooves at intervals along the outer periphery of the bearing portion (3142), a connecting hole is formed between the inner grooves and the inner wall of the venous pot (31), and the convex portion formed between adjacent inner grooves is connected to the inner wall of the venous pot (31).

12. The blood purification pipeline system according to claim 8, characterized in that: The venous pipeline assembly (3) further comprises a venous pot liquid inlet pipe (32), wherein the venous pot liquid inlet pipe (32) is connected to the liquid inlet port (311), and a first warming pot (321) is arranged on the venous pot liquid inlet pipe (32).

13. The blood purification pipeline system according to any one of claims 1 to 11, characterized in that: The blood purification pipeline system further comprises a dialysate pipeline assembly (6), wherein the dialysate pipeline assembly (6) is arranged at the pipeline installation position (51), one end of the dialysate pipeline assembly (6) is connected to a dialysate source, and the other end is connected to the filter assembly.

14. The blood purification pipeline system according to claim 13, characterized in that: The dialysate pipeline assembly (6) is provided with two dialysate branch pipelines (62) at one end away from the end connected to the dialysate source, wherein one of the dialysate branch pipelines (62) is connected to the filter assembly, and the other dialysate branch pipeline (62) is used to supplement the therapeutic liquid.

15. The blood purification pipeline system according to claim 13, characterized in that: The blood purification pipeline system also includes a replacement fluid pipeline assembly, which is arranged at the pipeline installation position (51), one end of the replacement fluid pipeline assembly is connected to the replacement fluid source, and the other end of the replacement fluid pipeline assembly is connected to the arterial pipeline assembly (1) and / or the venous pipeline assembly (3).

16. The blood purification pipeline system according to claim 15, characterized in that: The dialysate pipeline assembly (6) is also provided with a second warming pot (61), and the replacement fluid pipeline assembly is also provided with a third warming pot (713).

17. The blood purification pipeline system according to claim 15, characterized in that: The replacement fluid pipeline assembly comprises a first replacement fluid pipeline assembly (71) and a second replacement fluid pipeline assembly (72); the first replacement fluid pipeline assembly (71) can be selectively connected to the arterial pipeline assembly (1) or the venous pipeline assembly (3); and the second replacement fluid pipeline assembly (72) is connected to the arterial pipeline assembly (1).

18. The blood purification pipeline system according to claim 17, characterized in that: The blood purification pipeline system also includes a mixed fluid infusion pipeline assembly (8), which is arranged at the pipeline installation position (51), one end of the mixed fluid infusion pipeline assembly (8) is connected to the fluid infusion source, and the other end can be selectively connected to the arterial pipeline assembly (1) or the venous pipeline assembly (3).

19. The blood purification pipeline system according to claim 18, characterized in that: The blood purification device further comprises two pipeline selectors, the integrated disk (5) is provided with two pipeline selector fixing positions (54), and the two pipeline selectors are respectively fixed on the two pipeline selector fixing positions (54); The first replacement fluid pipeline assembly (71) comprises a front replacement fluid branch pipeline (711) and a rear replacement fluid branch pipeline (712), wherein the front replacement fluid branch pipeline (711) is connected to the arterial pipeline assembly (1), and the rear replacement fluid branch pipeline (712) is connected to the venous pipeline assembly (3), and one of the pipeline selectors can selectively open the front replacement fluid branch pipeline (711) or the rear replacement fluid branch pipeline (712); The mixed fluid infusion pipeline assembly (8) comprises a front fluid infusion branch pipeline (81) and a rear fluid infusion branch pipeline (82), wherein the front fluid infusion branch pipeline (81) is connected to the arterial pipeline assembly (1), and the rear fluid infusion branch pipeline (82) is connected to the venous pipeline assembly (3), and another pipeline selector can selectively open the front fluid infusion branch pipeline (81) or the rear fluid infusion branch pipeline (82).

20. The blood purification pipeline system according to claim 19, characterized in that: The blood purification pipeline system further comprises a waste liquid bag (9) and a waste liquid pipeline assembly (4); the waste liquid pipeline assembly (4) is arranged at the pipeline installation position (51); one end of the waste liquid pipeline assembly (4) is connected to the filter assembly, and the other end is connected to the waste liquid bag (9).

21. The blood purification pipeline system according to claim 20, characterized in that: The blood purification pipeline system further comprises a pre-flushing pipeline assembly (10), wherein the pre-flushing pipeline assembly (10) comprises a pre-flushing main pipeline (101) and a plurality of pre-flushing branch pipelines (102) connected to the pre-flushing main pipeline (101), wherein the pre-flushing main pipeline (101) is connected to a pre-flushing liquid source, the plurality of pre-flushing branch pipelines (102) are respectively connected to the arterial pipeline assembly (1), the liquid medicine input pipeline assembly (2) and the mixed liquid infusion pipeline assembly (8), and the venous pipeline assembly (3) is connected to the waste liquid bag (9); Alternatively, the priming main pipeline (101) is connected to a priming liquid source, and the plurality of priming branch pipelines (102) are respectively connected to the arterial pipeline assembly (1), the liquid medicine input pipeline assembly (2), the mixed fluid infusion pipeline assembly (8) and the venous pipeline assembly (3).

Images