Biological medicine processing and dissolving equipment
By designing a biopharmaceutical processing and dissolving equipment that includes stirring and cleaning, sealing, non-return and reverse stirring mechanisms, the problem of residues on the inner wall of the mixing equipment is solved, efficient cleaning of residues on the side walls of the dissolving cylinder is achieved, and the quality of the mixed liquid is ensured.
Patent Information
- Application Number
- CN202420171973.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-01-24
- Publication Date
- 2025-01-24
- Estimated Expiration
- 2034-01-24
AI Technical Summary
During the processing of biological medicines, particulate residues are prone to occur on the inner wall of the stirring equipment, and the failure to clean up will affect the quality of the next batch of mixed liquids prepared.
A biopharmaceutical processing and dissolving equipment is designed, including a dissolving cylinder, a stirring and cleaning mechanism, a sealing mechanism, a check mechanism and a reverse stirring mechanism. The motor drives the rotating tube and stirring tube to rotate, combined with the use of a water pump and sealing mechanism, to achieve efficient cleaning of residues on the side walls of the dissolving cylinder.
It effectively improves the cleaning effect of the equipment on the side wall of the dissolving cylinder, avoids the contamination of the granular materials by the residue for the next mixing, and ensures the quality of the mixed liquid.
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Figure CN222384558U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of biological medicine processing equipment, in particular to biological medicine processing and dissolving equipment. Background Art
[0002] Biopharmaceuticals refer to various biological products that are manufactured from organisms, biological tissues, cells, organs, body fluids, etc. using the research results of microbiology, biology, medicine, biochemistry, etc., and comprehensively utilizing the scientific principles and methods of microbiology, chemistry, biochemistry, biotechnology, pharmacy, etc.
[0003] Through searching, the patent document of Chinese Patent Publication No. CN213356277U was found. The device proposed in the patent document starts the first motor to reverse and lower the stirring shaft to a suitable position, then presses the spring downward to shrink, and then rotates the rotating plate outward to make the protrusion completely disengage from the concave groove. At this time, the rotating plate can be easily removed, thereby achieving the purpose of convenient replacement and maintenance.
[0004] However, in actual applications, it is found that the preparation of different medicines requires the mixing of different granular raw materials. After the granular raw materials are stirred, residues are likely to remain on the inner wall of the stirring equipment. Failure to clean the residues will result in the next batch of mixed liquid failing to meet the requirements. To this end, we provide a biopharmaceutical processing and dissolution equipment to solve the above problems. Utility Model Content
[0005] The purpose of the utility model is to make up for the deficiencies of the prior art and provide a biological medicine processing and dissolving device.
[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a biological drug processing and dissolution equipment, comprising a dissolving cylinder and a mounting shell, the dissolving cylinder is provided with a stirring and cleaning mechanism, the stirring and cleaning mechanism comprises a motor fixedly connected to the upper surface of the mounting shell, one end of the motor output shaft end passes through the mounting shell and is fixedly connected to a rotating tube, one end of the rotating tube passes through the top wall of the dissolving cylinder and is fixedly connected to evenly distributed stirring tubes, the bottom surface of the dissolving cylinder is fixedly connected to a water pump, and the output end of the water pump is connected to the inside of the dissolving cylinder.
[0007] Furthermore, a sealing mechanism is provided on the inner bottom wall of the dissolving cylinder, and the sealing mechanism includes a sealing shaft embedded in a reserved hole in the inner bottom wall of the dissolving cylinder, the sealing shaft is connected to the output end of the water pump, the reserved hole of the sealing shaft is rotatably connected to the lower end of the rotating tube, the reserved hole of the sealing shaft is connected to the reserved hole of the rotating tube, the lower end of the rotating tube is sleeved with a first sealing gasket, and the output end of the water pump is sleeved with a second sealing gasket, the output end of the water pump and the lower end of the rotating tube can be connected through the sealing shaft, and then the water can be drawn into the stirring tube through the rotating tube by the working water pump, and then sprayed onto the side wall of the dissolving cylinder through the stirring tube, thereby effectively improving the cleaning effect of the device and avoiding residue on the side wall of the dissolving cylinder to cause contamination when the granular material is stirred next time.
[0008] Furthermore, all the stirring tubes are provided with a check mechanism, which includes a first through groove opened in the stirring tube, a sphere matched with the first through groove is provided in the stirring tube, a second through groove is opened in the stirring tube, a compression spring is provided in the second through groove, the diameter of the second through groove is greater than the diameter of the first through groove, the diameter of the first through groove is greater than the diameter of the reserved hole of the stirring tube, and the sphere can prevent particles and water from flowing into the stirring tube and the rotating tube through the reserved hole of the stirring tube. When the inner wall of the dissolving cylinder needs to be cleaned, water will squeeze the sphere, the sphere will squeeze the compression spring, and the sphere will slide on the first through groove. When the sphere slides to the second through groove, the sphere will release the limitation on the reserved hole of the stirring tube, and the water flow will be sprayed onto the inner wall of the dissolving cylinder through the first through groove and the second through groove, thereby realizing the cleaning of the side wall of the dissolving cylinder.
[0009] Furthermore, a reverse stirring mechanism is provided in the mounting shell, and the reverse stirring mechanism includes a first bevel gear fixedly connected to the outer surface of the upper end of the rotating tube, the inner side wall of the mounting shell is rotatably connected to the second bevel gear through a bearing, the outer surface of the rotating tube is sleeved with a rotating cylinder, the rotating cylinder is rotatably connected to the top wall of the dissolving cylinder through a bearing, the upper end of the rotating cylinder is fixedly connected to a third bevel gear, the first bevel gear is meshed with the second bevel gear, the second bevel gear is meshed with the third bevel gear, and the outer surface of the rotating cylinder is fixedly connected with evenly distributed stirring plates. When the rotating tube rotates, the rotation of the rotating tube will drive the first bevel gear to rotate, the rotation of the first bevel gear will drive the second bevel gear to rotate, the rotation of the second bevel gear will drive the third bevel gear to rotate, and the rotation of the third bevel gear will drive the rotating cylinder to rotate on the surface of the rotating tube, and the rotation direction of the rotating cylinder is opposite to that of the rotating tube, so that the stirring plate fixed on the surface of the rotating cylinder and the stirring tube rotate in opposite directions, thereby realizing two-way stirring of the granular material inside the dissolving cylinder, so that the granular material is dissolved more thoroughly.
[0010] Furthermore, a bracket is fixedly connected to the bottom surface of the dissolving cylinder, and the device can be supported by arranging the bracket.
[0011] Furthermore, a cover plate is rotatably connected to the upper surface of the dissolving cylinder, and a handle is fixedly connected to the surface of the cover plate. The provision of the cover plate and the handle can prevent debris and dust from entering the interior of the dissolving cylinder.
[0012] Furthermore, a control valve is fixedly connected to the bottom surface of the dissolving cylinder, and the control valve is communicated with the interior of the dissolving cylinder. The control valve is provided to facilitate taking out the dissolved mixed liquid.
[0013] Compared with the existing technology, the biological drug processing and dissolution equipment has the following beneficial effects:
[0014] 1. The utility model can temporarily store particulate raw materials through the dissolving cylinder. The working motor drives the rotating tube to rotate, and the rotating tube will drive the stirring tube to rotate. The working water pump can pump clean water into the dissolving cylinder. The rotation of the stirring tube can rinse the residue on the side wall of the dissolving cylinder.
[0015] 2. The utility model can connect the water pump and the stirring tube by setting a sealing mechanism, and then can clean the residue on the side wall of the dissolving cylinder through the stirring tube, thereby improving the cleaning effect; the non-return mechanism can prevent the backflow of water with residue, and ensure the cleanliness of the reserved holes inside the stirring tube and the rotating tube; the particulate raw materials can be stirred in both directions by the reverse stirring mechanism, thereby improving the stirring effect and further improving the effect of cleaning the residue on the side wall; the bracket can be provided to support the device; the cover plate and the handle can prevent debris and dust from entering the inside of the dissolving cylinder; the control valve can be provided to facilitate the removal of the dissolved mixed liquid. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;
[0017] Figure 2 This is a schematic diagram of the internal structure of the utility model;
[0018] Figure 3 It is a cross-sectional schematic diagram of the internal structure of the utility model;
[0019] Figure 4 This is an enlarged schematic diagram of the structure at A of the utility model;
[0020] Figure 5 It is an enlarged schematic diagram of the structure at B of the utility model.
[0021] In the figure: 1. dissolving cylinder; 2. stirring and cleaning mechanism; 201. motor; 202. rotating tube; 203. stirring tube; 204. water pump; 3. sealing mechanism; 301. sealing shaft; 302. first sealing gasket; 303. second sealing gasket; 4. non-return mechanism; 401. first through groove; 402. sphere; 403. second through groove; 404. compression spring; 5. reverse stirring mechanism; 501. first bevel gear; 502. second bevel gear; 503. third bevel gear; 504. rotating cylinder; 505. stirring plate; 6. mounting shell; 7. bracket; 8. cover plate; 9. control valve; 10. handle. DETAILED DESCRIPTION
[0022] The principles and features of the present invention are described below in conjunction with the accompanying drawings. The examples given are only used to explain the present invention and are not used to limit the scope of the present invention.
[0023] This embodiment provides a biological drug processing and dissolution device, which can effectively remove the mixed liquid remaining on the inner wall of the stirring device to avoid affecting the particulate raw materials that need to be stirred in the next step.
[0024] See also Figure 1 to Figure 5 A biological drug processing and dissolution equipment includes a dissolving cylinder 1 and a mounting shell 6. The dissolving cylinder 1 is provided with a stirring and cleaning mechanism 2. The stirring and cleaning mechanism 2 includes a motor 201 fixedly connected to the upper surface of the mounting shell 6. The output shaft end of the motor 201 passes through one end of the mounting shell 6 and is fixedly connected to a rotating tube 202. The rotating tube 202 passes through one end of the top wall of the dissolving cylinder 1 and is fixedly connected to evenly distributed stirring tubes 203. The bottom surface of the dissolving cylinder 1 is fixedly connected to a water pump 204, and the output end of the water pump 204 is connected to the inside of the dissolving cylinder 1.
[0025] See also Figure 3 The mounting shell 6 is fixedly connected to the upper surface of the dissolving cylinder 1, and there are reserved holes at the lower end of the rotating tube 202 and the inside of the stirring tube 203, and the rotating tube 202 and the stirring tube 203 are connected. When the motor 201 is started, the starting of the motor 201 will drive the rotating tube 202 to rotate, and the rotation of the rotating tube 202 will drive the stirring tube 203 fixed on the rotating tube 202 to rotate, and the granular material and the solution can be fully mixed through the rotating stirring tube 203.
[0026] When cleaning the residue inside the dissolving cylinder 1 , the water pump 204 can transport water into the dissolving cylinder 1 , and the rotating stirring tube 203 and the water can effectively improve the cleaning effect of the device.
[0027] A sealing mechanism 3 is provided on the inner bottom wall of the dissolving cylinder 1, and the sealing mechanism 3 includes a sealing shaft 301 embedded in a reserved hole on the inner bottom wall of the dissolving cylinder 1, the sealing shaft 301 is connected to the output end of the water pump 204, the reserved hole of the sealing shaft 301 is rotatably connected to the lower end of the rotating tube 202, the reserved hole of the sealing shaft 301 is connected to the reserved hole of the rotating tube 202, the lower end of the rotating tube 202 is sleeved with a first sealing gasket 302, and the output end of the water pump 204 is sleeved with a second sealing gasket 303.
[0028] See also Figure 4 By providing the first sealing gasket 302 and the second sealing gasket 303, the connection between the output end 204 and the sealing shaft 301 can be sealed, and the connection between the lower end of the rotating tube 202 and the sealing shaft 301 can be sealed to avoid water leakage.
[0029] The output end of the water pump 204 can be connected to the lower end of the rotating tube 202 through the sealing shaft 301, and then the working water pump 204 can draw water into the stirring tube 203 through the rotating tube 202, and then spray it to the side wall of the dissolving cylinder 1 through the stirring tube 203, thereby effectively improving the cleaning effect of the device and avoiding residue on the side wall of the dissolving cylinder 1 to cause pollution when the granular material is stirred next time.
[0030] All stirring tubes 203 are provided with a check mechanism 4, which includes a first through groove 401 opened in the stirring tube 203, a sphere 402 matched with the first through groove 401 is provided in the first through groove 401, a second through groove 403 is opened in the stirring tube 203, a compression spring 404 is provided in the second through groove 403, the diameter value of the second through groove 403 is greater than the diameter value of the first through groove 401, and the diameter value of the first through groove 401 is greater than the diameter value of the reserved hole of the stirring tube 203.
[0031] The sphere 402 can prevent particles and water from flowing into the stirring tube 203 and the rotating tube 202 through the reserved holes of the stirring tube 203. When the inner wall of the dissolving tube 1 needs to be cleaned, the water will squeeze the sphere 402, and the sphere 402 will squeeze the compression spring 404, and the sphere 402 will slide on the first through groove 401.
[0032] When the ball 402 slides to the second through groove 403, the ball 402 will release the limit on the reserved hole of the stirring tube 203, and the water flow will be sprayed onto the inner wall of the dissolving cylinder 1 through the first through groove 401 and the second through groove 403, thereby cleaning the side wall of the dissolving cylinder 1.
[0033] See also Figure 5Preferably, the first through groove 401 is adapted to the sphere 402 , and the diameter of the second through groove 403 is greater than the diameter of the first through groove 401 , so that when the sphere 402 moves to the second through groove 403 under the pressure of water, water can flow out through the gap between the second through groove 403 and the sphere 402 .
[0034] A reverse stirring mechanism 5 is provided in the mounting shell 6, and the reverse stirring mechanism 5 includes a first bevel gear 501 fixedly connected to the outer surface of the upper end of the rotating tube 202, and the inner wall of the mounting shell 6 is rotatably connected to the second bevel gear 502 through a bearing, and the outer surface of the rotating tube 202 is sleeved with a rotating cylinder 504.
[0035] The rotating cylinder 504 is rotatably connected to the top wall of the dissolving cylinder 1 through a bearing, and the upper end of the rotating cylinder 504 is fixedly connected to the third bevel gear 503, the first bevel gear 501 is meshed with the second bevel gear 502, and the second bevel gear 502 is meshed with the third bevel gear 503, and the outer surface of the rotating cylinder 504 is fixedly connected to evenly distributed stirring plates 505.
[0036] When the rotating tube 202 rotates, the rotation of the rotating tube 202 will drive the first bevel gear 501 to rotate, the rotation of the first bevel gear 501 will drive the second bevel gear 502 to rotate, the rotation of the second bevel gear 502 will drive the third bevel gear 503 to rotate, and the rotation of the third bevel gear 503 will drive the rotating cylinder 504 to rotate on the surface of the rotating tube 202.
[0037] The rotating cylinder 504 rotates in the opposite direction to the rotating tube 202, so that the stirring plate 505 fixed on the surface of the rotating cylinder 504 and the stirring tube 203 rotate in opposite directions, thereby achieving two-way stirring of the granular material inside the dissolving cylinder 1, so that the granular material is dissolved more thoroughly.
[0038] The bottom surface of the dissolving cylinder 1 is fixedly connected with a bracket 7, and the bracket 7 can support the device. The bracket 7 increases the contact area between the device and the ground, and effectively improves the stability of the device.
[0039] The upper surface of the dissolving cylinder 1 is rotatably connected to a cover plate 8, and the surface of the cover plate 8 is fixedly connected to a handle 10. The handle 10 provides a reasonable force point for opening the cover plate 8, which facilitates the opening and closing of the cover plate 8. The cover plate 8 can prevent debris and dust from entering the dissolving cylinder 1 and causing pollution to the inside of the dissolving cylinder 1, thereby polluting the mixed solution after the particulate raw materials are dissolved.
[0040] The bottom surface of the dissolving cylinder 1 is fixedly connected with a control valve 9, and the control valve 9 is communicated with the inside of the dissolving cylinder 1. The control valve 9 is provided to facilitate taking out the dissolved mixed liquid.
[0041] Working principle: When stirring the granular material and the solution, the motor 201 is started first. The start of the motor 201 will drive the rotating tube 202 and the stirring tube 203 to rotate. The rotation of the rotating tube 202 will also drive the first bevel gear 501 to rotate. The first bevel gear 501 will drive the second bevel gear 502 to rotate. The second bevel gear 502 will drive the rotating cylinder 504 and the stirring plate 505 to rotate. The stirring plate 505 and the stirring tube 203 rotate in opposite directions, thereby being able to stir the granular material and the solution in the dissolving cylinder 1 in both directions, effectively improving the granular material and the solution of the device. The dissolving effect of the solution, when the dissolution is completed and the equipment needs to be cleaned, the water pump 204 is started while the motor 201 is started. The water pump 204 can pump water into the rotating tube 202 and the stirring tube 203 through the sealing shaft 301. The water in the stirring tube 203 squeezes the ball 402 and the compression spring 404, so that the water is sprayed out to the side wall of the dissolving cylinder 1 through the second through groove 403. Under the cooperation of the spraying of water flow and the rotation of the stirring tube 203 and the stirring plate 505, the cleaning effect of the equipment is effectively improved, and the solution residue on the side wall of the dissolving cylinder 1 is prevented from affecting the dissolution of the next batch of granular materials.
Claims
1. A biological drug processing and dissolution device, comprising a dissolution cylinder (1) and a mounting shell (6), characterized in that: The dissolving cylinder (1) is provided with a stirring and cleaning mechanism (2), the stirring and cleaning mechanism (2) comprising a motor (201) fixedly connected to the upper surface of the mounting shell (6), one end of the output shaft end of the motor (201) passing through the mounting shell (6) is fixedly connected to a rotating tube (202), one end of the rotating tube (202) passing through the top wall of the dissolving cylinder (1) is fixedly connected to evenly distributed stirring tubes (203), the bottom surface of the dissolving cylinder (1) is fixedly connected to a water pump (204), and the output end of the water pump (204) is connected to the inside of the dissolving cylinder (1).
2. A biopharmaceutical processing and dissolution equipment according to claim 1, characterized in that: The inner bottom wall of the dissolving cylinder (1) is provided with a sealing mechanism (3), and the sealing mechanism (3) comprises a sealing shaft (301) embedded in a reserved hole in the inner bottom wall of the dissolving cylinder (1), the sealing shaft (301) is connected to the output end of the water pump (204), the reserved hole of the sealing shaft (301) is rotatably connected to the lower end of the rotating tube (202), the reserved hole of the sealing shaft (301) is connected to the reserved hole of the rotating tube (202), the lower end of the rotating tube (202) is sleeved with a first sealing gasket (302), and the output end of the water pump (204) is sleeved with a second sealing gasket (303).
3. A biopharmaceutical processing and dissolving device according to claim 1, characterized in that: All the stirring tubes (203) are provided with a check mechanism (4) inside, the check mechanism (4) comprising a first through groove (401) opened inside the stirring tube (203), a sphere (402) matched therewith being provided inside the first through groove (401), a second through groove (403) opened inside the stirring tube (203), a compression spring (404) being provided inside the second through groove (403), the diameter value of the second through groove (403) being greater than the diameter value of the first through groove (401), and the diameter value of the first through groove (401) being greater than the diameter value of the reserved hole of the stirring tube (203).
4. A biopharmaceutical processing and dissolving device according to claim 1, characterized in that: A reverse stirring mechanism (5) is arranged inside the mounting shell (6), and the reverse stirring mechanism (5) comprises a first bevel gear (501) fixedly connected to the outer surface of the upper end of the rotating tube (202); the inner side wall of the mounting shell (6) is rotatably connected to the second bevel gear (502) via a bearing; the outer surface of the rotating tube (202) is sleeved with a rotating cylinder (504); the rotating cylinder (504) is rotatably connected to the top wall of the dissolving cylinder (1) via a bearing; the upper end of the rotating cylinder (504) is fixedly connected to the third bevel gear (503); the first bevel gear (501) is meshed with the second bevel gear (502); the second bevel gear (502) is meshed with the third bevel gear (503); and the outer surface of the rotating cylinder (504) is fixedly connected to uniformly distributed stirring plates (505).
5. The biopharmaceutical processing and dissolution equipment according to claim 1, characterized in that: A bracket (7) is fixedly connected to the bottom surface of the dissolving cylinder (1).
6. The biopharmaceutical processing and dissolving equipment according to claim 1, characterized in that: The upper surface of the dissolving cylinder (1) is rotatably connected to a cover plate (8), and the surface of the cover plate (8) is fixedly connected to a handle (10).
7. The biopharmaceutical processing and dissolution equipment according to claim 1, characterized in that: A control valve (9) is fixedly connected to the bottom surface of the dissolving cylinder (1), and the control valve (9) is in communication with the interior of the dissolving cylinder (1).
Citation Information
Patent Citations
Stirring and filling equipment for biological medicine preparation
CN213356277U