Stem cell sorting device

Abstract

The utility model provides a stem cell sorting device, which relates to the technical field of stem cell extraction, and comprises a mounting box and a processing box, the inner bottom of the mounting box is uniformly and fixedly connected with a plurality of motors, the output ends of the plurality of motors movably penetrate through the inner bottom of the mounting box, the output ends of the plurality of motors are fixedly connected with insertion blocks, and the insertion blocks are fixedly connected with the processing box. And mounting bases are arranged on the outer surfaces of the multiple inserting blocks correspondingly, first hand screwing bolts penetrate through the front surfaces of the multiple mounting bases in a threaded mode correspondingly, grinding heads are fixedly connected to the bottoms of the multiple mounting bases correspondingly, and positioning holes are formed in the front surfaces of the multiple inserting blocks correspondingly. According to the grinding device, the inserting block, the positioning hole, the mounting base, the first hand-screwing bolt, the fixing hole, the mounting frame, the grinding groove and the second hand-screwing bolt are used in cooperation, the grinding head and the grinding table can be detached, and therefore the grinding head and the grinding table can be conveniently taken out to be cleaned or maintained, and components on the surfaces and in the grinding head and the grinding table can be better cleaned; and it is ensured that attached substances are thoroughly removed, and the cleaning effect and efficiency are improved.

Description

Technical Field

[0001] The utility model relates to the technical field of stem cell extraction, in particular to a stem cell sorting device. Background Art

[0002] Stem cells are cells with the potential for self-replication and differentiation. They can continuously self-renew and differentiate into various types of cells under specific conditions, including nerve cells, cardiomyocytes, liver cells, etc. Stem cells have wide application value in the medical field, such as disease treatment and tissue regeneration.

[0003] In the prior art, for example, Chinese patent publication number CN220485697U discloses a stem cell sorting device, wherein four vertical support rods are arranged in the housing, a grinding table is fixed on the upper part of the support rods, a lifting rod is arranged at each of the four corners of the grinding table, a grinding box is fixed on the upper end of the lifting rods, a grinding motor is arranged in the grinding box, a grinding head is connected to the output shaft of the grinding motor, a grinding groove matching the grinding head is arranged on the grinding table, the bottom of the grinding groove penetrates the grinding table, two symmetrical holders are arranged on the lower side of the grinding table, a sieve plate is clamped between the two holders, and a through hole aligned with the bottom of the grinding groove is arranged on the sieve plate. The sorting device grinds the tissue through the grinding device, and then directly drops it into the sedimentation tank to sort out the stem cells. The structure is simple, and closed operation can be realized. Moreover, the grinding is performed by the grinding motor, which can reduce the intervention of human operation.

[0004] In the above patent, after the tissue is ground by a grinding device, it falls directly into a sedimentation tank to select stem cells. Its structure is simple and can realize closed operation. However, after grinding by the grinding table and the grinding head, some substances will adhere to it and need to be cleaned to avoid subsequent cross infection. However, the grinding table and the grinding head are both inside the box, which limits the space for cleaning operations and increases the complexity and time of cleaning. Utility Model Content

[0005] The purpose of the utility model is to solve the problem in the above patent that after the tissue is ground by a grinding device, it directly falls into a sedimentation tank to select stem cells. The structure is simple and closed operation can be realized. However, after grinding by the grinding table and the grinding head, some substances will adhere to the surface, which needs to be cleaned to avoid subsequent cross infection. However, the grinding table and the grinding head are both inside the box, which limits the space for cleaning operations and increases the complexity and time-consumingness of cleaning. A stem cell sorting device is proposed.

[0006] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a stem cell sorting device, comprising: an installation box and a processing box, the inner bottom of the installation box is evenly fixedly connected with a plurality of motors, the output ends of the plurality of motors are movably penetrated with the inner bottom of the installation box, the output ends of the plurality of motors are fixedly connected with plug-ins, the outer surfaces of the plurality of plug-ins are provided with mounting seats, the front surfaces of the plurality of mounting seats are threaded with first hand-tightened bolts, the bottoms of the plurality of mounting seats are fixedly connected with grinding heads, the front surfaces of the plurality of plug-ins are provided with positioning holes, the inner bottom of the processing box is evenly fixedly connected with a plurality of support rods, the tops of the plurality of support rods are fixedly connected with a limiting frame, the inner surface of the limiting frame is inserted with a mounting frame, the inner surface of the mounting frame is fixedly connected with a grinding table, the bottom of the limiting frame is symmetrically threaded with second hand-tightened bolts, and the top of the mounting frame is symmetrically provided with fixing holes.

[0007] Preferably, the plurality of first hand-tightening bolts are respectively matched with the plurality of positioning holes, and the inner surfaces of the plurality of mounting seats are respectively matched with the outer surfaces of the plurality of insert blocks.

[0008] Preferably, the two second hand-tightening bolts are respectively matched with the two fixing holes, and the inner surface of the limiting frame and the outer surface of the mounting frame are slidably arranged.

[0009] Preferably, a plurality of grinding grooves are equidistantly formed on the top of the grinding table, and the plurality of grinding grooves are respectively matched with a plurality of grinding heads.

[0010] Preferably, a fixing frame is symmetrically fixedly connected to the bottom of the grinding table, a slide board is movably connected between the inner surfaces of the two fixing frames, a rectangular block is fixedly connected to the bottom of the mounting frame, a threaded rod is threaded through the front surface of the rectangular block, and the rear surface of the threaded rod is rotatably connected to the front surface of the slide board.

[0011] Preferably, electric push rods are symmetrically fixedly connected to the top of the processing box, and the driving ends of the two electric push rods are fixedly connected to the top of the installation box. A collection box is provided at the inner bottom of the processing box.

[0012] Preferably, the position of the collecting box matches the positions of the plurality of grinding grooves, and the outer surface of the processing box is provided with an alarm, a timer and a controller in sequence.

[0013] Compared with the prior art, the advantages and positive effects of the utility model are:

[0014] 1. In the utility model, the grinding head and the grinding table can be disassembled by using the insert block, the positioning hole, the mounting seat, the first hand-tightened bolt, the fixing hole, the mounting frame, the grinding groove and the second hand-tightened bolt, so as to facilitate the removal, cleaning or maintenance of the grinding head and the grinding table, better clean the surface and internal parts thereof, ensure the thorough removal of the attached substances, and improve the cleaning effect and efficiency.

[0015] 2. In the utility model, the controller, timer and alarm are used in combination to automatically control the grinding time of the grinding head on the cell tissue, and with the cooperation of the alarm, the staff can perform intermittent work on the device to ensure the grinding effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 A three-dimensional diagram of a stem cell sorting device proposed by the utility model;

[0017] Figure 2 This is a schematic diagram of the structure of an installation box for a stem cell sorting device proposed in the utility model;

[0018] Figure 3 This is a partial structural schematic diagram of a stem cell sorting device proposed by the utility model;

[0019] Figure 4 The utility model provides a schematic diagram of the bottom of a grinding table of a stem cell sorting device.

[0020] Legend: 1. Controller; 2. Timer; 3. Alarm; 4. Electric push rod; 5. Mounting box; 6. Grinding table; 7. Limiting frame; 8. Collection box; 9. Motor; 10. Insert block; 11. Positioning hole; 12. Mounting seat; 13. First hand-tightening bolt; 14. Grinding head; 15. Fixing hole; 16. Mounting frame; 17. Grinding groove; 18. Second hand-tightening bolt; 19. Slide plate; 20. Fixing frame; 21. Threaded rod; 22. Rectangular block; 23. Support rod; 24. Processing box. DETAILED DESCRIPTION

[0021] In order to more clearly understand the above-mentioned purpose, features and advantages of the utility model, the utility model is further described below in conjunction with the accompanying drawings and embodiments. It should be noted that the embodiments of the present application and the features in the embodiments can be combined with each other without conflict.

[0022] In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention may also be implemented in other ways than those described herein. Therefore, the present invention is not limited to the specific embodiments of the following disclosure.

[0023] Embodiment 1, as Figure 1-Figure 4As shown, the utility model provides a stem cell sorting device, including: an installation box 5 and a processing box 24, the inner bottom of the installation box 5 is evenly fixedly connected with a plurality of motors 9, the output ends of the plurality of motors 9 are movably penetrated with the inner bottom of the installation box 5, the output ends of the plurality of motors 9 are fixedly connected with plug blocks 10, the outer surfaces of the plurality of plug blocks 10 are provided with mounting seats 12, the front surfaces of the plurality of mounting seats 12 are threadedly penetrated with first hand-tightening bolts 13, the bottoms of the plurality of mounting seats 12 are fixedly connected with grinding heads 14, the front surfaces of the plurality of plug blocks 10 are provided with positioning holes 11, the inner bottom of the processing box 24 is evenly fixedly connected with a plurality of support rods 23, the tops of the plurality of support rods 23 are fixedly connected with a limiting frame 7, the inner surface of the limiting frame 7 is inserted with a mounting frame 16, the inner surface of the mounting frame 16 is fixedly connected with a grinding table 6, the bottom of the limiting frame 7 is symmetrically threaded with second hand-tightening bolts 18, the top of the mounting frame 16 is symmetrically provided with fixing holes 15, and the plurality of The first hand-tightening bolts 13 are respectively matched with the multiple positioning holes 11, the inner surfaces of the multiple mounting seats 12 are respectively matched with the outer surfaces of the multiple plug-in blocks 10, the two second hand-tightening bolts 18 are respectively matched with the two fixing holes 15, the inner surface of the limit frame 7 is slidably arranged with the outer surface of the mounting frame 16, the top of the grinding table 6 is equidistantly provided with multiple grinding grooves 17, and the multiple grinding grooves 17 are respectively matched with the multiple grinding heads 14, the bottom of the grinding table 6 is symmetrically fixedly connected with a fixing frame 20, and a slide plate 19 is movably connected between the inner surfaces of the two fixing frames 20, and a rectangular block 22 is fixedly connected to the bottom of the mounting frame 16, and a threaded rod 21 is threaded through the front surface of the rectangular block 22, and the rear surface of the threaded rod 21 is rotatably connected to the front surface of the slide plate 19, and the top of the processing box 24 is symmetrically fixedly connected with an electric push rod 4, and the driving ends of the two electric push rods 4 are fixedly connected to the top of the mounting box 5, and a collection box 8 is provided at the inner bottom of the processing box 24.

[0024] The effect achieved by the entire embodiment 1 is that the controller 1 is electrically connected to the timer 2, the alarm 3, the electric push rod 4 and the motor 9, which is an existing mature technology. When extracting stem cells, the cell tissue is placed along the grinding groove 17, and then the door of the processing box 24 is closed, and then the electric push rod 4 is started by the controller 1 to drive the installation box 5 and the grinding head 14 to move downward, so that the grinding head 14 enters the grinding groove 17, and then the motor 9 is started to drive the mounting seat 12 and the grinding head 14 to rotate to grind the stem cells inside the grinding groove 17. As the grinding proceeds, the electric push rod 4 can continue to descend, and at the same time, the grinding groove 17 penetrates the grinding table 6. During grinding, the grinding groove 17 can be blocked by the slide plate 19. When the grinding is completed, the threaded rod 21 can be rotated to drive the slide plate 19 to slide on the two fixing frames 20, so that the through hole on the slide plate 19 is aligned with the grinding groove 17, and the ground material falls into the collection box 8. The physiological saline stored in the collection box 8 and the ground tissue are precipitated in the collection box 8 to obtain The precipitate is a stem cell. After the work is finished, the first hand-tightening bolt 13 can be turned to disengage the first hand-tightening bolt 13 from the positioning hole 11, so that the mounting seat 12 can be disengaged from the plug block 10, and the grinding head 14 can be taken out from the processing box 24. The second hand-tightening bolt 18 can be turned to disengage the second hand-tightening bolt 18 from the fixing hole 15, so that the mounting frame 16 can be pulled out from the limiting frame 7, and the grinding table 6 can be taken out from the processing box 24, so that the grinding head 14 and the grinding table 6 can be taken out for cleaning or removal. Maintenance, better clean its surface and internal components, ensure complete removal of attached substances, improve cleaning effect and efficiency, when installing, insert the plug 10 into the mounting seat 12, and then first hand-tighten the bolt 13 to insert it into the positioning hole 11, complete the installation of the mounting seat 12, that is, complete the installation of the grinding head 14, align the mounting frame 16 with the limiting frame 7, insert the mounting frame 16 into the limiting frame 7, and then turn the second hand-tighten bolt 18 to insert it into the fixing hole 15 to complete the installation of the grinding table 6.

[0025] Embodiment 2, as Figure 1-Figure 4 As shown, the position of the collecting box 8 matches the positions of the plurality of grinding grooves 17, and the outer surface of the processing box 24 is provided with an alarm 3, a timer 2 and a controller 1 in sequence.

[0026] The effect achieved by the entire embodiment 2 is that when the motor 9 is in the startup process, a time threshold can be set through the timer 2, so that when the timer 2 reaches the set time, the electrical signal will be transmitted to the controller 1, the controller 1 ends and processes, and the motor 9 is turned off, thereby automatically controlling the degree of cell tissue grinding, and another time threshold can be set through the timer 2. When the set time is reached, the electrical signal will be transmitted to the controller 1, the controller 1 ends and processes, and the alarm 3 is started to notify the staff to stop the device, so that the device can work intermittently to avoid excessive temperature of the grinding head 14 and the grinding table 6, which will cause damage to the cell tissue.

[0027] Working principle: When the cell tissue is ground by the motor 9, the grinding head 14 and the grinding groove 17, during the starting process of the motor 9, a time threshold can be set by the timer 2, so that when the timer 2 reaches the set time, the electrical signal will be transmitted to the controller 1, the controller 1 ends and processes, and the motor 9 is turned off, so as to automatically control the degree of cell tissue grinding, and another time threshold can be set by the timer 2. When the set time is reached, the electrical signal will be transmitted to the controller 1, the controller 1 ends and processes, and the alarm 3 is started to notify the staff to stop the device, so that the device works intermittently to avoid the grinding head 14 and the grinding groove 17. The temperature of the table 6 is too high, causing damage to the cell tissue. When the work is completed, the first hand-tightening bolt 13 can be turned to disengage the first hand-tightening bolt 13 from the positioning hole 11, so that the mounting seat 12 can be disengaged from the plug block 10, and the grinding head 14 can be taken out of the processing box 24, and the second hand-tightening bolt 18 can be turned to disengage the second hand-tightening bolt 18 from the fixing hole 15, so that the mounting frame 16 can be pulled out from the limiting frame 7, and the grinding table 6 can be taken out of the processing box 24, so as to facilitate the removal, cleaning or maintenance of the grinding head 14 and the grinding table 6, better clean their surfaces and internal components, ensure that the attached substances are completely removed, and improve the cleaning effect and efficiency.

[0028] The above description is only a preferred embodiment of the present invention and does not limit the present invention in other forms. Any technician familiar with the profession may use the technical content disclosed above to change or modify it into an equivalent embodiment with equivalent changes and apply it to other fields. However, any simple modification, equivalent change and modification made to the above embodiment based on the technical essence of the present invention without departing from the content of the technical solution of the present invention still falls within the protection scope of the technical solution of the present invention.

Claims

1. A stem cell sorting device, characterized in that: include: The invention relates to an installation box (5) and a processing box (24), wherein a plurality of motors (9) are evenly and fixedly connected to the inner bottom of the installation box (5), the output ends of the plurality of motors (9) are movably penetrated with the inner bottom of the installation box (5), the output ends of the plurality of motors (9) are fixedly connected to plug blocks (10), the outer surfaces of the plurality of plug blocks (10) are provided with installation seats (12), the front surfaces of the plurality of installation seats (12) are threadedly penetrated with first hand-tightening bolts (13), the bottoms of the plurality of installation seats (12) are fixedly connected to grinding heads (14), and the plurality of The front surface of each of the insert blocks (10) is provided with a positioning hole (11); the inner bottom of the processing box (24) is evenly fixedly connected with a plurality of support rods (23); the tops of the plurality of support rods (23) are fixedly connected with a limiting frame (7); the inner surface of the limiting frame (7) is provided with a mounting frame (16); the inner surface of the mounting frame (16) is fixedly connected with a grinding table (6); the bottom of the limiting frame (7) is symmetrically threaded with a second hand-tightened bolt (18); and the top of the mounting frame (16) is symmetrically provided with fixing holes (15).

2. The stem cell sorting device according to claim 1, characterized in that: The plurality of first hand-tightening bolts (13) are respectively matched with the plurality of positioning holes (11), and the inner surfaces of the plurality of mounting seats (12) are respectively matched with the outer surfaces of the plurality of insert blocks (10).

3. The stem cell sorting device according to claim 2, characterized in that: The two second hand-tightening bolts (18) are respectively matched with the two fixing holes (15), and the inner surface of the limiting frame (7) and the outer surface of the mounting frame (16) are slidably arranged.

4. The stem cell sorting device according to claim 3, characterized in that: A plurality of grinding grooves (17) are equidistantly provided on the top of the grinding table (6), and the plurality of grinding grooves (17) are respectively matched with the plurality of grinding heads (14).

5. The stem cell sorting device according to claim 4, characterized in that: The bottom of the grinding table (6) is symmetrically fixedly connected to a fixing frame (20), and a slide plate (19) is movably connected between the inner surfaces of the two fixing frames (20). The bottom of the mounting frame (16) is fixedly connected to a rectangular block (22), and a threaded rod (21) is threadedly penetrated through the front surface of the rectangular block (22), and the rear surface of the threaded rod (21) is rotatably connected to the front surface of the slide plate (19).

6. The stem cell sorting device according to claim 5, characterized in that: The top of the processing box (24) is symmetrically fixedly connected with electric push rods (4), and the driving ends of the two electric push rods (4) are fixedly connected to the top of the installation box (5). The inner bottom of the processing box (24) is provided with a collection box (8).

7. The stem cell sorting device according to claim 6, characterized in that: The position of the collecting box (8) matches the positions of the plurality of grinding grooves (17), and the outer surface of the processing box (24) is provided with an alarm (3), a timer (2) and a controller (1) in sequence.

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