Electrophoresis clamp

Through the designable electrical fixture, the problem that can only be applied to a single thickness sample in the existing technology can be solved, and the synchronous clamping and electrical separation of different thickness samples can be achieved, which improves the efficiency of electrical separation and the practicality of clamps.

CN222420082UActive Publication Date: 2025-01-28WUHAN BAILEBO BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202420769681.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-15
Publication Date
2025-01-28
Estimated Expiration
2034-04-15

AI Technical Summary

Technical Problem

Existing electrophoretic fixtures are usually only suitable for samples of a single thickness, and there are limitations when clamping against multiple sample plates, making it difficult to clamp samples of multiple sizes.

Method used

A electrical fixture that includes the installation base, partition, splint and adjustment component. By adjusting the component, the splint can be adjusted according to the thickness of the sample to adapt to samples of different thickness, and improve the stability between the installation base and the electrical tank through a fixed component.

Benefits of technology

The synchronous clamping and electrical separation of different thickness samples are realized, the efficiency of electrical separation is improved, and the practicality of the electro -swimming fixture is enhanced.

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Abstract

The utility model discloses an electrophoresis clamp which comprises an installation base, a partition plate is fixedly connected to the outer side of the installation base, a clamping plate is installed on the outer side of the installation base, and an adjusting assembly is arranged between the clamping plate and the installation base. The adjusting assembly comprises slide ways formed in the surface and the side wall of the mounting base, and the inner sides of the slide ways are movably connected with connecting rods with one ends fixedly connected with the clamping plates. Under the pushing of the adjusting seat, the connecting rod moves through the slide way and synchronously drives the clamping plate, so that a sample between the clamping plate and the partition plate can be clamped, after the sample is clamped, the adjusting column and the adjusting groove in the fixing seat are limited and locked under the action of the reset spring, and when a second sample with different thicknesses needs to be clamped, the adjusting column is fixed to the adjusting groove in the fixing seat. Meanwhile, the position of the adjusting seat is adjusted and locked, so that samples with different thicknesses can be synchronously separated during electrophoretic separation of the samples with different thicknesses, the electrophoretic separation efficiency is improved, and meanwhile, the practicability of the electrophoresis clamp is enhanced.
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Description

Technical Field

[0001] The utility model relates to the field of biotechnology, in particular to an electrophoresis clamp. Background Art

[0002] Electrophoresis is a commonly used biological separation technology. It uses electric fields to move charged particles in gel or liquid media and separates them according to their size, shape and charge. Electrophoresis is widely used in molecular biology, protein chemistry, genetic engineering and other fields. Electrophoresis fixtures are auxiliary tools in electrophoresis experiments. They are used to fix and support electrophoresis samples to help separate and analyze samples.

[0003] Existing electrophoresis clamps are usually designed to be suitable for samples of specific thickness, which means that these electrophoresis clamps may only be able to clamp samples of a single thickness; some electrophoresis clamps may also have adjustable clamping parts so that they can adapt to gels or samples of different thicknesses, but such electrophoresis clamps with adjustable clamping thickness are mostly used independently, and have limitations when clamping multiple sample plates, making it inconvenient to clamp samples of various sizes and types in the same set of electrophoresis clamps. Utility Model Content

[0004] The utility model aims to provide an electrophoresis clamp to solve the problems existing in the prior art.

[0005] To achieve the above purpose, the technical solution adopted by the utility model is: comprising a mounting base, a partition is fixedly connected to the outer side of the mounting base, a clamp is installed on the outer side of the mounting base, and an adjustment component is provided between the clamp and the mounting base;

[0006] The adjustment assembly includes a slideway opened on the surface and side wall of the mounting base, the inner side of the slideway is movably connected to a connecting rod with one end fixedly connected to the clamping plate, the end of the connecting rod away from the clamping plate is fixedly connected to an adjustment seat, the inner side of the adjustment seat is movably connected to an adjustment column, a return spring is fixedly connected between the adjustment column and the adjustment seat, the side wall of the mounting base is fixedly connected to a fixing seat, and an adjustment groove is opened on the side of the fixing seat close to the adjustment seat.

[0007] By adopting the above technical solution and setting up an adjustment component, the clamping plate can be adjusted, so that samples of different thicknesses can be clamped, so that samples of different thicknesses can be electrophoretically separated synchronously.

[0008] Furthermore, the mounting base is in a "concave" shape, a mounting groove is provided on the bottom wall of the mounting base, and a cover plate for sealing the mounting groove is fixedly connected to the lower end of the mounting base.

[0009] By adopting the above technical solution and the arrangement of the cover plate, the connecting rod can be conveniently disassembled and assembled.

[0010] Furthermore, the connecting rod is in an "L" shape, and both ends of the connecting rod are located on the inner sides of the two slideways, and the diameter of the connecting rod is adapted to the width of the slideway.

[0011] By adopting the above technical solution, the slideway cooperates with the connecting rod, so that the connecting rod can drive the clamping plate to move its position.

[0012] Furthermore, a movable hole is formed at one end of the adjustment seat away from the connecting rod, and the number of the adjustment seats is the same as the number of the clamping plates.

[0013] By adopting the above technical solution and setting the movable hole, the handle can drive the adjusting column to move its position.

[0014] Furthermore, a handle is fixedly connected to the outer side of the adjusting column, and the handle is located on the inner side of the movable hole. One end of the adjusting column passes through and extends to the outer side of the adjusting seat.

[0015] By adopting the above technical solution and setting the handle, the adjustment column is more convenient to adjust.

[0016] Furthermore, the number of the adjustment slots is several, and the adjustment slots are in the shape of a right-angled trapezoid, and the specification of the adjustment column close to one end of the adjustment slot is adapted to the specification of the adjustment slot.

[0017] By adopting the above technical solution, the adjustment groove and the adjustment column cooperate with each other, so that the position of the adjustment seat can be locked.

[0018] Furthermore, a fixing assembly is installed on the side wall of the mounting base, and the fixing assembly includes a threaded sleeve movably installed on the side wall of the mounting base, the inner side of the threaded sleeve is threadedly connected to a threaded rod, and one end of the threaded rod away from the threaded sleeve is fixedly connected to a fixing plate.

[0019] By adopting the above technical solution, the arrangement of the fixed component is made so that the installation between the mounting base and the electrophoresis box is more stable, thereby preventing the mounting base from tipping over in the electrophoresis box.

[0020] Furthermore, the number of the threaded sleeves is two and they are symmetrically distributed; the threaded sleeves are movably connected to the mounting base via bearings; and the outer sides of the threaded sleeves are fixedly connected to anti-slip pads.

[0021] By adopting the above technical solution and providing the anti-skid pad, slipping can be avoided when the threaded sleeve is rotated.

[0022] Compared with the prior art, the beneficial effects of the utility model are:

[0023] 1. By setting up an adjustment component, under the push of the adjustment seat, the connecting rod moves through the slide, and synchronously drives the clamping plate, so that the sample between the clamping plate and the partition can be clamped. After the sample is clamped, the adjustment column is limited and locked with the adjustment groove on the fixed seat under the action of the reset spring. When it is necessary to clamp a second sample of different thickness, the adjustment seat is also adjusted and locked. Therefore, when performing electrophoretic separation of samples of different thicknesses, the samples of different thicknesses can be performed synchronously, which improves the efficiency of electrophoretic separation and enhances the practicality of the electrophoresis clamp; 2. By setting up a fixing component, when the threaded sleeve rotates, the threaded rod can drive the fixing plate to fit closely with the inner wall of the electrophoresis box, thereby improving the stability between the mounting base and the electrophoresis box. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a schematic diagram of the overall three-dimensional structure of the utility model;

[0025] Figure 2 This is a schematic diagram of the cross-sectional structure of the installation base of the utility model;

[0026] Figure 3 For this utility model Figure 2 The enlarged structural diagram at A in the middle;

[0027] Figure 4 This is a cross-sectional structural diagram of the connection between the threaded sleeve and the mounting base of the utility model;

[0028] Figure 5 This is a schematic diagram of the structure in which the installation base 1 of the present invention is located inside the electrophoresis box.

[0029] In the figure: 1. mounting base; 101. mounting groove; 102. cover plate; 2. partition plate; 3. clamping plate; 4. adjustment assembly; 41. slideway; 42. connecting rod; 43. adjustment seat; 431. movable hole; 44. adjustment column; 441. handle; 45. reset spring; 46. fixing seat; 47. adjustment groove; 5. fixing assembly; 51. threaded sleeve; 511. anti-slip pad; 52. threaded rod; 53. fixing plate; 531. rubber pad. DETAILED DESCRIPTION

[0030] The following will be combined with the drawings in the utility model to clearly and completely describe the technical solution of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0031] In the description of the present invention, it should be noted that the directions or positional relationships indicated by terms such as "middle", "upper", "lower", "left", "right", "inside" and "outside" are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention.

[0032] Embodiment 1, as Figure 1 —4, the specific scheme of the embodiment is as follows: it includes a mounting base 1, the mounting base 1 is "concave", the bottom wall of the mounting base 1 is provided with a mounting groove 101, the lower end of the mounting base 1 is fixedly connected with a cover plate 102 for covering the mounting groove 101, the cover plate 102 is fixedly connected to the mounting groove 101 by fixing bolts, the outer side of the mounting base 1 is fixedly connected with a partition 2, the number of the partitions 2 is two, and they are symmetrically distributed, the outer side of the mounting base 1 is installed with a splint 3, the number of the splints 3 is several, and the specifications of the several splints 3 are the same as the specifications of the partition 2, and an adjustment component 4 is provided between the splint 3 and the mounting base 1.

[0033] The adjustment assembly 4 comprises a slideway 41 provided on the surface and side wall of the mounting base 1, the inner side of the slideway 41 is movably connected to a connecting rod 42 having one end fixedly connected to the clamping plate 3, the connecting rod 42 is "L" shaped, and the two ends of the connecting rod 42 are located on the inner sides of the two slideways (41), and the diameter of the connecting rod 42 is adapted to the width of the slideway (41);

[0034] The end of the connecting rod 42 away from the splint 3 is fixedly connected with an adjusting seat 43, and the end of the adjusting seat 43 away from the connecting rod 42 is provided with a movable hole 431. The number of the adjusting seats 43 is the same as the number of the splints 3. The side wall of the adjusting seat 43 is provided with a through hole. The inner side of the adjusting seat 43 is movably connected with an adjusting column 44. The adjusting column 44 is "T"-shaped, and one end of the adjusting column 44 is located on the inner side of the through hole. The outer side of the adjusting column 44 is fixedly connected with a handle 441, and the handle 441 is located on the inner side of the movable hole 431. The handle 441 can drive the adjusting column 44 to move its position. One end of the adjusting column 44 passes through and extends to the outer side of the adjusting seat 43. A return spring 45 is fixedly connected between the adjusting column 44 and the adjusting seat 43.

[0035] The side wall of the mounting base 1 is fixedly connected with a fixing seat 46, and an adjustment slot 47 is provided on a side of the fixing seat 46 close to the adjustment seat 43. The number of the adjustment slots 47 is several, and the adjustment slots 47 are in the shape of a right-angled trapezoid. The specification of the end of the adjustment column 44 close to the adjustment slot 47 is adapted to the specification of the adjustment slot 47.

[0036] In the second embodiment, a fixing component 5 is installed on the side wall of the mounting base 1, and the fixing component 5 includes a threaded sleeve 51 movably installed on the side wall of the mounting base 1, and a gap is provided between the threaded sleeve 51 and the partition 2. The number of the threaded sleeves 51 is two, and they are symmetrically distributed. The threaded sleeve 51 is movably connected to the mounting base 1 through a bearing, and the outer side of the threaded sleeve 51 is fixedly connected to an anti-skid pad 511, which can increase the friction force and prevent the threaded sleeve 51 from falling off when rotating. The inner side of the threaded sleeve 51 is threadedly connected to a threaded rod 52, and the end of the threaded rod 52 away from the threaded sleeve 51 is fixedly connected to a fixing plate 53, and the end of the fixing plate 53 away from the threaded rod 52 is fixedly connected to a rubber pad 531. The provision of the rubber pad 531 can prevent the fixing plate 53 from scratching the electrophoresis box.

[0037] The working principle of the above embodiment is:

[0038] When it is necessary to perform electrophoretic separation on samples of different thicknesses, the first sample is placed between the partition 2 and the clamping plate 3, and the adjustment seat 43 is manually pushed. With the cooperation of the slide 41, the adjustment seat 43 drives the connecting rod 42 to move its position, and synchronously drives the clamping plate 3 to clamp its first sample. After clamping, with the cooperation of the reset spring 45, the adjustment column 44 and the adjustment groove 47 are locked in position. After locking, the second sample of different thickness is placed between the two clamping plates 3, and the adjustment seat 43 is synchronously pushed to fix it. After all the samples are fixed, the mounting base 1 is placed in the electrophoresis box (such as Figure 5 As shown), after it is put in, the threaded sleeve 51 is rotated so that the threaded rod 52 inside the threaded sleeve 51 drives the fixing plate 53 to extend until the fixing plate 53 is tightly fitted with the inner wall of the electrophoresis box. After fitting, the sample can be separated by electrophoresis.

[0039] Although the embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An electrophoresis fixture, characterized in that: It comprises a mounting base (1), a partition plate (2) is fixedly connected to the outer side of the mounting base (1), a clamping plate (3) is installed on the outer side of the mounting base (1), and an adjustment component (4) is provided between the clamping plate (3) and the mounting base (1); The adjustment assembly (4) comprises a slideway (41) provided on the surface and side wall of the mounting base (1); the inner side of the slideway (41) is movably connected to a connecting rod (42) having one end fixedly connected to the clamping plate (3); the end of the connecting rod (42) away from the clamping plate (3) is fixedly connected to an adjustment seat (43); the inner side of the adjustment seat (43) is movably connected to an adjustment column (44); a return spring (45) is fixedly connected between the adjustment column (44) and the adjustment seat (43); the side wall of the mounting base (1) is fixedly connected to a fixing seat (46); and an adjustment groove (47) is provided on a side of the fixing seat (46) close to the adjustment seat (43).

2. An electrophoresis fixture according to claim 1, characterized in that: The mounting base (1) is in a "concave" shape, a mounting groove (101) is provided on the bottom wall of the mounting base (1), and a cover plate (102) for sealing the mounting groove (101) is fixedly connected to the lower end of the mounting base (1).

3. The electrophoresis fixture according to claim 1, characterized in that: The connecting rod (42) is in an "L" shape, and both ends of the connecting rod (42) are located inside the two slideways (41). The diameter of the connecting rod (42) is adapted to the width of the slideways (41).

4. The electrophoresis fixture according to claim 1, characterized in that: A movable hole (431) is provided at one end of the adjustment seat (43) away from the connecting rod (42), and the number of the adjustment seats (43) is the same as the number of the clamping plates (3).

5. The electrophoresis fixture according to claim 4, characterized in that: A handle (441) is fixedly connected to the outer side of the adjustment column (44), and the handle (441) is located on the inner side of the movable hole (431). One end of the adjustment column (44) passes through and extends to the outer side of the adjustment seat (43).

6. The electrophoresis fixture according to claim 1, characterized in that: The number of the adjustment slots (47) is several, and the adjustment slots (47) are in the shape of a right-angled trapezoid. The specification of the end of the adjustment column (44) close to the adjustment slot (47) is compatible with the specification of the adjustment slot (47).

7. The electrophoresis fixture according to claim 1, characterized in that: A fixing assembly (5) is installed on the side wall of the mounting base (1), and the fixing assembly (5) comprises a threaded sleeve (51) movably installed on the side wall of the mounting base (1), a threaded rod (52) is threadedly connected to the inner side of the threaded sleeve (51), and a fixing plate (53) is fixedly connected to one end of the threaded rod (52) away from the threaded sleeve (51).

8. The electrophoresis fixture according to claim 7, characterized in that: The number of the threaded sleeves (51) is two and they are symmetrically distributed. The threaded sleeves (51) are movably connected to the mounting base (1) via a bearing, and the outer side of the threaded sleeve (51) is fixedly connected to an anti-slip pad (511).