Folic acid concentration determination sample pretreatment device

Abstract

The utility model discloses a folic acid concentration determination sample pretreatment device, and relates to the technical field of folic acid concentration pretreatment. A fixing plate is arranged on the base, a cover body is arranged on the base, a centrifugal motor is arranged in the base, a moving block is arranged at the bottom of the fixing plate in a sliding fit mode, a positioning pin is arranged on one side of the moving block, a rotating rod is arranged on an output shaft of the centrifugal motor, an inserting groove is formed in the rotating rod, and the positioning pin is inserted into the inserting groove. A placing rack is arranged on the rotating rod, a sample tube is arranged on the placing rack, and a test tube cylinder is arranged on the fixed plate. The sample tube is placed on the lantern ring block, the rubber ring between the sample tube and the lantern ring block has damping force, the situation that the sample tube is separated from the lantern ring block during centrifugal operation is reduced, the lantern ring block rotates on the placing frame, and therefore it can be guaranteed that the sample tube can be kept in a vertical state during stirring or after centrifugation is finished; during centrifugation, the sample tube can automatically rotate towards the horizontal direction.

Description

Technical Field

[0001] The utility model belongs to the field of folic acid concentration pretreatment, and in particular relates to a folic acid concentration determination sample pretreatment device. Background Art

[0002] Folic acid, vitamin B9, in the prior art, is a water-soluble B vitamin, which is composed of pterin, p-aminobenzoic acid (pABA) and one or more glutamic acids. It is a colorless and tasteless yellow or orange crystal or crystalline powder, insoluble in organic solvents such as ethanol and ether, soluble in alkaline solutions such as ammonia water and potassium hydroxide, extremely unstable under acidic conditions, and easily destroyed under light conditions, especially under ultraviolet radiation. Organisms generally need folic acid, but different organisms have different ways to obtain this nutrient. Animals themselves cannot synthesize folic acid, but can obtain it by ingesting food. Plants and some microorganisms can completely biosynthesize folic acid. The existing fixed inclined centrifugal structure accumulates liquid on the outer wall of the sample tube for centrifugation, resulting in residual liquid near the closed cover when the sample is opened after centrifugation.

[0003] In view of this, the present utility model is proposed. Utility Model Content

[0004] The technical problem to be solved by the utility model is to overcome the deficiencies of the prior art and provide a sample pretreatment device for determining folic acid concentration.

[0005] In order to solve the above technical problems, the basic concept of the technical solution adopted by the utility model is:

[0006] A sample pretreatment device for measuring folic acid concentration, comprising a base, a fixing plate mounted on the base, a cover body disposed on the base, a centrifugal motor mounted in the base, and a moving block slidably matched at the bottom of the fixing plate;

[0007] A positioning pin is installed on one side of the moving block, a rotating rod is installed on the output shaft of the centrifugal motor, a slot is opened on the rotating rod, the positioning pin is inserted in the slot, a placing rack is installed on the rotating rod, a sample tube is arranged on the placing rack, a test tube tube is installed on the fixed plate, and a fixing component is arranged in the test tube tube.

[0008] Optionally, a plurality of collar blocks are rotatably engaged on the placement rack, a slot is provided on the placement rack, connecting columns are installed on opposite sides of the collar blocks, the connecting columns are rotatably engaged in the slots, a rubber ring is installed on the inner wall of the collar block, and a tube cap is provided on the sample tube; by placing the sample tube on the collar block, the rubber ring between the sample tube and the collar block has a damping force, and the resistance is greater than the centrifugal force of the placement rack driven by the centrifugal motor to rotate, thereby reducing the situation where the sample tube is separated from the collar block during centrifugal operation, and the collar block rotates on the placement rack, thereby ensuring that the sample tube will remain in a vertical state during stirring or after centrifugation.

[0009] Optionally, a bevel groove is provided on the moving block, a limit groove is provided on the fixed plate, a limit block is installed on the moving block, the limit block slides in the limit groove, a first spring is installed on one side of the limit block, a bevel block is installed on one side of the cover body, the bevel block cooperates with one side of the bevel groove; when the cover body is opened, the bevel block of the cover body is separated from the bevel groove, and the moving block slides on the bottom of the fixed plate under the action of the first spring, thereby driving the positioning pin to be inserted into the slot to position the rotating rotating rod.

[0010] Optionally, the fixing assembly includes a rotating cylinder rotatably fitted in the test tube cylinder, a placement plate slidably fitted in the rotating cylinder, a plurality of clamping frames slidably fitted in the placement ring, and a connecting frame rotatably fitted in the bottom of the rotating cylinder, arc grooves are provided on opposite sides of the rotating cylinder, connecting shafts are installed on opposite sides of the placement plate, the connecting shafts slide in the arc grooves, a fixing sleeve is installed at the bottom of the placement plate, a fixing rod is installed on the test tube cylinder, a spring is installed on the fixing rod, the fixing sleeve slides on the fixing rod, and the spring is located in the fixing sleeve.

[0011] Optionally, a fixed plate is installed at the bottom of the rotating cylinder, a first connecting column is installed at the bottom of the fixed plate, a through groove is provided at the bottom of the rotating cylinder, a connecting ring is provided at the bottom of the rotating cylinder, a clamping block is provided on one side of the clamping frame, a slider is provided at the bottom of the clamping frame, a second connecting column is installed at the bottom of the slider, two connecting grooves are provided on the connecting frame, the second connecting column rotatably fits in one of the connecting grooves, the first connecting column rotatably fits in the other connecting groove, a plurality of sliding grooves are provided on the test tube barrel, the slider slidably fits in the sliding groove, an annular groove is provided on the test tube barrel, and the connecting ring rotatably fits in the annular groove.

[0012] After adopting the above technical solution, the utility model has the following beneficial effects compared with the prior art. Of course, any product implementing the utility model does not necessarily need to achieve all the advantages described below at the same time:

[0013] The folic acid concentration determination sample pretreatment device places the sample tube on the collar block, and the rubber ring between the sample tube and the collar block has a damping force. The resistance is greater than the centrifugal force of the centrifugal motor driving the placement rack to rotate, thereby reducing the situation where the sample tube is separated from the collar block during centrifugal operation. The collar block rotates on the placement rack, thereby ensuring that the sample tube will remain in a vertical state during stirring or after the centrifugation is completed. During centrifugation, the sample tube will automatically rotate toward a horizontal direction. When the cover body is opened, the bevel block of the cover body is separated from the bevel groove, and the moving block slides at the bottom of the fixed plate through the force of the first spring, thereby driving the positioning pin to be inserted into the slot to position the rotating rotating rod. Since the number of slots opened is only one, after each positioning, the order of the sample tubes on the placement rack from left to right will not be confused, thereby facilitating the comparison processing of multiple samples. When the cover body is connected to the base, the bevel block of the cover body contacts the bevel of the bevel groove to pull the moving block, so that the positioning pin is separated from the slot, thereby contacting the limit of the rotating rod, thereby performing centrifugal operation.

[0014] The specific implementation of the utility model is further described in detail below with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The drawings described below are only some embodiments. For those skilled in the art, other drawings can be obtained based on these drawings without creative work. In the drawings:

[0016] Figure 1 It is a schematic diagram of the overall structure of the embodiment of the utility model;

[0017] Figure 2 This is a schematic diagram of the structure in which the bevel block of the embodiment of the utility model is located on the moving block;

[0018] Figure 3 This is a schematic diagram of the structure of the bevel block detaching from the moving block in an embodiment of the utility model;

[0019] Figure 4 This is a schematic diagram of the structure of the placement rack according to an embodiment of the utility model;

[0020] Figure 5 This is a schematic diagram of the structure of the sample tube connection of the embodiment of the utility model;

[0021] Figure 6 This is a schematic diagram of the structure of the fixing assembly of the utility model embodiment

[0022] Figure 7 This is a schematic diagram of the exploded structure of the fixing assembly of the utility model embodiment

[0023] Figure 8 This is a schematic diagram of the structure of the rotating drum in the embodiment of the utility model.

[0024] Fig. 9 This is a schematic diagram of the structure of the bottom plate of the test tube tube of the utility model embodiment

[0025] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0026] 1-base, 2-fixed plate, 3-cover, 4-centrifugal motor, 5-test tube, 6-rotating tube, 7-placing plate, 8-clamping frame, 9-connecting frame, 10-ring block, 11-sample tube, 12-tube cap, 13-connecting column, 14-rubber ring, 201-moving block, 202-locating pin, 203-bevel groove, 204-limiting groove, 205-limiting block, 206-first spring, 301-bevel block, 40 1-rotating rod, 402-slot, 403-placing frame, 404-slot hole, 501-slide groove, 502-annular groove, 503-fixing rod, 504-spring, 601-arc groove, 602-fixing plate, 603-first connecting column, 604-through groove, 605-connecting ring, 701-connecting shaft, 702-fixing sleeve, 801-clamping block, 802-sliding block, 803-second connecting column, 901-connecting groove.

[0027] It should be noted that these drawings and textual descriptions are not intended to limit the conceptual scope of the present invention in any way, but rather to illustrate the concept of the present invention for those skilled in the art by referring to specific embodiments. DETAILED DESCRIPTION

[0028] The utility model will now be further described in detail with reference to the accompanying drawings.

[0029] See also Figure 1-9 As shown, in this embodiment, a sample pretreatment device for measuring folic acid concentration is provided, comprising a base 1, a fixing plate 2 is mounted on the base 1, a cover 3 is arranged on the base 1, a centrifugal motor 4 is mounted in the base 1, and a moving block 201 is slidably matched at the bottom of the fixing plate 2;

[0030] A positioning pin 202 is installed on one side of the moving block 201, and a rotating rod 401 is installed on the output shaft of the centrifugal motor 4. A slot 402 is opened on the rotating rod 401, and the positioning pin 202 is inserted into the slot 402. A placement rack 403 is installed on the rotating rod 401, and a sample tube 11 is arranged on the placement rack 403. A test tube tube 5 is installed on the fixed plate 2, and a fixing component is arranged in the test tube tube 5.

[0031] In this embodiment, a plurality of collar blocks 10 are rotatably engaged on the placement rack 403, a slot 404 is provided on the placement rack 403, connecting posts 13 are installed on opposite sides of the collar block 10, the connecting posts 13 are rotatably engaged in the slot 404, a rubber ring 14 is installed on the inner wall of the collar block 10, and a tube cap 12 is provided on the sample tube 11; by placing the sample tube 11 on the collar block 10, the rubber ring 14 between the sample tube 11 and the collar block 10 has a damping force, and the resistance is greater than the centrifugal force driven by the centrifugal motor 4 to drive the placement rack 403 to rotate, thereby reducing the situation where the sample tube 11 is separated from the collar block 10 during the centrifugal operation, and the collar block 10 rotates on the placement rack 403, thereby ensuring that the sample tube 11 will remain in a vertical state during stirring or after the centrifugation, and the sample tube 11 will automatically rotate toward the horizontal direction during centrifugation.

[0032] In this embodiment, the moving block 201 is provided with a bevel groove 203, the fixed plate 2 is provided with a limit groove 204, the moving block 201 is provided with a limit block 205, the limit block 205 is slidably matched in the limit groove 204, one side of the limit block 205 is provided with a first spring 206, one side of the cover body 3 is provided with a bevel block 301, the bevel block 301 is matched with one side of the bevel groove 203; when the cover body 3 is opened, the bevel block 301 of the cover body 3 is separated from the bevel groove 203, and the moving block 201 slides on the bottom of the fixed plate 2 by the force of the first spring 206, so that The positioning pin 202 is driven to be inserted into the slot 402 to position the rotating rod 401. Since there is only one slot 402, the order of the sample tubes 11 on the placement rack 403 from left to right will not be confused after each positioning, which is convenient for comparison processing of multiple samples. When the cover body 3 is connected to the base 1, the bevel block 301 of the cover body 3 contacts the bevel of the bevel groove 203 to pull the moving block 201, so that the positioning pin 202 is disengaged from the slot 402, thereby contacting the limit of the rotating rod 401, thereby performing centrifugal operation.

[0033] The fixing assembly of this embodiment includes a rotating cylinder 6 rotatably fitted in the test tube cylinder 5, a placement plate 7 slidably fitted in the rotating cylinder 6, a plurality of clamping frames 8 slidably fitted in the placement ring 2, and a connecting frame 9 rotatably fitted at the bottom of the rotating cylinder 6. The rotating cylinder 6 is provided with arc grooves 601 on opposite sides, the placement plate 7 is provided with connecting shafts 701 on opposite sides, the connecting shafts 701 are slidably fitted in the arc grooves 601, a fixing sleeve 702 is provided at the bottom of the placement plate 7, a fixing plate 5 is provided with a fixing rod 503, a spring 504 is provided on the fixing rod 503, the fixing sleeve 702 is slidably fitted on the fixing rod 503, and the spring 504 is located in the fixing sleeve 702.

[0034] The bottom of the rotating cylinder 6 of this embodiment is equipped with a fixed plate 602, the bottom of the fixed plate 602 is equipped with a first connecting column 603, the bottom of the rotating cylinder 6 is provided with a through groove 604, the bottom of the rotating cylinder 6 is provided with a connecting ring 605, one side of the clamping frame 8 is provided with a clamping block 801, the bottom of the clamping frame 8 is provided with a sliding block 802, the bottom of the sliding block 802 is provided with a second connecting column 803, the connecting frame 9 is provided with two connecting grooves 901, the second connecting column 803 is rotatably fitted in one of the connecting grooves 901, the first connecting column 603 is rotatably fitted in the other connecting groove 901, and a plurality of sliding grooves 501 are provided on the test tube cylinder 5. The block 802 is slidably fitted in the slide groove 501, an annular groove 502 is opened on the test tube barrel 5, and the connecting ring 605 is rotatably fitted in the annular groove 502; the connecting shaft 701 arranged on both sides of the placement plate 7 is slidably fitted in the arc groove 601 of the rotating cylinder 6, so that when the placement plate 7 moves downward, the connecting shaft 701 slides in the arc groove 601 to drive the rotating cylinder 6 to rotate, so that it has a linkage effect, and the fixed sleeve 702 of the placement plate 7 is sleeved on the fixed rod 503 of the test tube barrel 5, and the spring 504 arranged on the fixed rod 503 can clamp reagent tubes of different sizes according to the depth of the downward movement of the thromboelastogram cup body 3.

[0035] The present invention is not limited to the above-mentioned implementation modes. Anyone should be aware of the structural changes made under the inspiration of the present invention. Any technical solution that is the same or similar to the present invention falls within the protection scope of the present invention. The technology, shape, and structure that are not described in detail in the present invention are all known technologies.

Claims

1. A sample pretreatment device for measuring folic acid concentration, characterized in that: include: A base (1), a fixed plate (2) is mounted on the base (1), a cover (3) is arranged on the base (1), a centrifugal motor (4) is mounted inside the base (1), and a moving block (201) is slidably matched at the bottom of the fixed plate (2); A positioning pin (202) is installed on one side of the moving block (201); a rotating rod (401) is installed on the output shaft of the centrifugal motor (4); a slot (402) is provided on the rotating rod (401); the positioning pin (202) is inserted into the slot (402); a placement rack (403) is installed on the rotating rod (401); a sample tube (11) is arranged on the placement rack (403); a test tube cylinder (5) is installed on the fixing plate (2); a fixing component is arranged in the test tube cylinder (5).

2. A sample pretreatment device for measuring folic acid concentration according to claim 1, characterized in that: A plurality of collar blocks (10) are rotatably engaged on the placement rack (403), a slot hole (404) is provided on the placement rack (403), connecting posts (13) are installed on opposite sides of the collar block (10), the connecting posts (13) are rotatably engaged in the slot hole (404), a rubber ring (14) is installed on the inner wall of the collar block (10), and a tube cap (12) is provided on the sample tube (11).

3. A sample pretreatment device for measuring folic acid concentration according to claim 2, characterized in that: The movable block (201) is provided with a bevel groove (203), the fixed plate (2) is provided with a limit groove (204), the movable block (201) is provided with a limit block (205), the limit block (205) is slidably matched in the limit groove (204), a first spring (206) is provided on one side of the limit block (205), and a bevel block (301) is provided on one side of the cover body (3), the bevel block (301) is matched with one side of the bevel groove (203).

4. A sample pretreatment device for measuring folic acid concentration according to claim 1, characterized in that: The fixing assembly comprises a rotating cylinder (6) rotatably fitted in the test tube cylinder (5), a placement plate (7) slidably fitted in the rotating cylinder (6), a plurality of clamping frames (8) slidably fitted in the test tube cylinder (5), and a connecting frame (9) rotatably fitted at the bottom of the rotating cylinder (6).

5. A sample pretreatment device for measuring folic acid concentration according to claim 4, characterized in that: The rotating cylinder (6) is provided with arc grooves (601) on opposite sides, the placing plate (7) is provided with connecting shafts (701) on opposite sides, the connecting shafts (701) are slidably fitted in the arc grooves (601), a fixing sleeve (702) is provided at the bottom of the placing plate (7), a fixing rod (503) is provided on the test tube cylinder (5), a spring (504) is provided on the fixing rod (503), the fixing sleeve (702) is slidably fitted on the fixing rod (503), and the spring (504) is located in the fixing sleeve (702).

6. A sample pretreatment device for measuring folic acid concentration according to claim 5, characterized in that: A fixed disk (602) is installed at the bottom of the rotating cylinder (6), a first connecting column (603) is installed at the bottom of the fixed disk (602), a through groove (604) is opened at the bottom of the rotating cylinder (6), a connecting ring (605) is installed at the bottom of the rotating cylinder (6), a clamping block (801) is installed on one side of the clamping frame (8), a sliding block (802) is installed at the bottom of the clamping frame (8), and a second connecting column (803) is installed at the bottom of the sliding block (802).

7. A sample pretreatment device for measuring folic acid concentration according to claim 6, characterized in that: The connecting frame (9) is provided with two connecting grooves (901), the second connecting column (803) is rotatably fitted in one of the connecting grooves (901), the first connecting column (603) is rotatably fitted in the other connecting groove (901), the test tube barrel (5) is provided with a plurality of sliding grooves (501), the sliding block (802) is slidably fitted in the sliding grooves (501), the test tube barrel (5) is provided with an annular groove (502), and the connecting ring (605) is rotatably fitted in the annular groove (502).

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