Continuous efficient cooling equipment for cyanogen diester production

Abstract

The utility model discloses continuous efficient cooling equipment for cyanogen diester production, which comprises a jacketed reaction kettle and a cooling bin, the cooling bin is arranged on one side of the jacketed reaction kettle, an upper flow guide channel and a lower flow guide channel are symmetrically arranged in the cooling bin in the vertical direction, and the upper flow guide channel is communicated with the lower flow guide channel. The utility model relates to the technical field of cyanogen diester production cooling equipment, an existing jacket type reaction kettle is improved, a cooling bin is arranged on one side of the jacket type reaction kettle, the cooling bin is arranged on the other side of the jacket type reaction kettle, and a vertical multi-channel spiral heat exchange assembly is connected between the upper flow guide channel and the lower flow guide channel. A plurality of groups of parallel vertical multi-channel spiral heat exchange assemblies are arranged in the cooling bin, a reaction mixture in the reaction kettle is injected through a lower flow guide channel by utilizing a liquid guide pump and ascends along the vertical multi-channel spiral heat exchange assemblies, and the reaction mixture exchanges heat with low-temperature cooling liquid in the cooling bin for cooling in the process; and the cooled reaction mixture flows back into the reaction kettle.

Description

Technical Field

[0001] The utility model relates to the technical field of cooling equipment for cyanodiester production, in particular to continuous high-efficiency cooling equipment for cyanodiester production. Background Art

[0002] Cyanide is an important intermediate in the synthesis route of pregabalin. The synthesis process of cyanide is that trimethylbutyraldehyde and diethyl malonate react with a catalyst in n-heptane as a solvent to generate a condensate by condensation reaction, and the condensate is then reacted with sodium cyanide to generate cyanide. During the process, it is necessary to add a tetrahydrofuran solution of 2-halogenated-4-methylvaleronitrile to the reaction mixture, and stir overnight at room temperature under nitrogen protection to cool the reaction mixture to 0 degrees Celsius. In the prior art, most of them use ice-salt bath cooling to cool the entire reactor, but this cooling form has low cooling efficiency and is not suitable for large-scale batch continuous production. The use of liquid nitrogen equipment for cooling and temperature reduction operation control is relatively complicated and costly. In view of this, in-depth research on the above-mentioned problems led to the emergence of this case. Utility Model Content

[0003] In view of the deficiencies of the prior art, the utility model provides a continuous high-efficiency cooling device for the production of cyanodiester, which solves the problems raised in the background technology.

[0004] To achieve the above purpose, the utility model is implemented through the following technical scheme: a continuous and efficient cooling equipment for cyanodiester production, comprising a jacketed reactor and a cooling bin, wherein the cooling bin is arranged on one side of the jacketed reactor, and an upper guide channel and a lower guide channel are symmetrically arranged in the vertical direction in the cooling bin, and a vertical multi-channel spiral heat exchange component is connected between the upper guide channel and the lower guide channel, a liquid guide pump is connected to the bottom discharge end of the jacketed reactor, and the outlet end of the liquid guide pump is connected to the lower guide channel, and one end of the upper guide channel is connected to the jacketed reactor, and a water cooling circulation component is arranged on one side of the jacketed reactor and the cooling bin, and the water cooling circulation component is respectively connected to the jacketed reactor and the cooling bin.

[0005] The vertical multi-channel spiral heat exchange assembly includes a support, a spiral heat exchange tube and a sealing joint. The support is fixed in the cooling bin. The spiral heat exchange tube is fixed by the support and the upper and lower ends are respectively connected to the upper guide channel and the lower guide channel through sealing joints.

[0006] The above-mentioned water-cooling circulation component includes a circulating water tank, an industrial refrigerator and a booster pump. The circulating water tank is arranged on one side of the cooling tank, the industrial refrigerator is connected to the circulating water tank, the water inlet end of the booster pump is connected to the circulating water tank, and the water outlet end of the booster pump is provided with a water supply pipe, and the water supply pipe is respectively connected to the interlayer space of the jacketed reactor and the cooling tank, and the interlayer space and the upper part of the cooling tank are connected to the circulating water tank through a return water pipe.

[0007] A one-way valve and a flow regulating valve are installed on the water supply pipeline.

[0008] A temperature probe is arranged in the above-mentioned circulating water tank.

[0009] An expansion valve is arranged on the top of the circulating water tank.

[0010] The utility model provides a continuous and efficient cooling device for the production of cyanodiester. It has the following beneficial effects: the continuous and efficient cooling device for the production of cyanodiester improves the existing jacketed reactor, a cooling bin is arranged on one side of the jacketed reactor, a plurality of sets of parallel vertical multi-channel spiral heat exchange components are arranged in the cooling bin, a liquid guide pump is used to inject the reaction mixture in the reactor through the lower guide channel, and the reaction mixture goes up along the vertical multi-channel spiral heat exchange component, and heat is exchanged and cooled with the low-temperature coolant in the cooling bin during the process, and the reaction mixture after cooling flows back into the reactor, and the interlayer space of the reactor is also cooled and kept at a constant temperature by the low-temperature coolant provided by the water cooling circulation component at the same time, and the structure is simple, the equipment operation and maintenance cost is low, and large-scale continuous batch production can be realized. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] Figure 1 This is a schematic diagram of the main structure of a continuous and efficient cooling device for producing cyanodiester described in the utility model.

[0012] Figure 2 The utility model is a partial cross-sectional structural schematic diagram of a continuous high-efficiency cooling device for producing cyanodiester.

[0013] In the figure: 1. Jacketed reactor; 2. Cooling chamber; 3. Upper guide channel; 4. Lower guide channel; 5. Liquid guide pump; 6. Support; 7. Spiral heat exchange tube; 8. Sealing joint; 9. Circulating water tank; 10. Industrial refrigerator; 11. Booster pump; 12. One-way valve; 13. Flow control valve; 14. Temperature probe; 15. Expansion valve. DETAILED DESCRIPTION

[0014] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0015] Through the personnel in this field, all the electrical components in this case are connected to their corresponding power supplies through wires, and a suitable controller should be selected according to the actual situation to meet the control requirements. The specific connection and control sequence should refer to the following working principle, and the electrical connection between the electrical components is completed in the order of working in sequence. The detailed connection means are well-known technologies in this field. The following mainly introduces the working principle and process, and does not explain the electrical control.

[0016] Embodiment: In conjunction with the specification Figure 1-2 It can be seen that the present scheme specifically designs a continuous and efficient cooling device for the production of cyanodiester, wherein a cooling bin 2 is arranged on one side of a jacketed reactor 1, and an upper guide channel 3 and a lower guide channel 4 are symmetrically arranged in the vertical direction in the cooling bin 2, and a vertical multi-channel spiral heat exchange component is connected between the upper guide channel 3 and the lower guide channel 4, and a liquid guide pump 5 is connected to the bottom discharge end of the jacketed reactor, and the outlet end of the liquid guide pump 5 is connected to the lower guide channel 4, and one end of the upper guide channel 3 is connected to the jacketed reactor 1, and a water cooling circulation component is arranged on one side of the jacketed reactor 1 and the cooling bin 2, and the water cooling circulation component is respectively connected to the jacketed reactor 1 and the cooling bin 2, wherein the vertical multi-channel spiral heat exchange component includes The support 6, the spiral heat exchange tube 7 and the sealing joint 8, the support 6 is fixed in the cooling bin 2, the spiral heat exchange tube 7 is fixed by the support 6, and the upper and lower ends are respectively connected with the upper guide channel 3 and the lower guide channel 4 through the sealing joints 8. When in use, the reaction mixture in the reactor is injected through the lower guide channel 4 by the liquid guide pump 5, and goes up along the vertical multi-channel spiral heat exchange component. In this process, heat exchange and cooling are carried out with the low-temperature coolant in the cooling bin 2. The reaction mixture after cooling flows back into the reactor. The interlayer space of the reactor is also cooled synchronously by the low-temperature coolant provided by the water-cooling circulation component and the constant temperature is maintained after cooling. The structure is simple, the equipment operation and maintenance cost is low, and large-scale continuous batch production can be realized.

[0017] In the specific implementation process, as a preferred setting, the above-mentioned water-cooled circulation component includes a circulating water tank 9, an industrial refrigerator 10 and a booster pump 11. The circulating water tank 9 is arranged on one side of the cooling tank 2, the industrial refrigerator 10 is connected to the circulating water tank 9, the water inlet end of the booster pump 11 is connected to the circulating water tank 9, and the water outlet end of the booster pump 11 is provided with a water supply pipe, which is respectively connected to the interlayer space of the jacketed reactor 1 and the cooling tank 2, and the interlayer space and the upper part of the cooling tank 2 are connected to the circulating water tank 9 through a return water pipe, wherein a one-way valve 12 and a A flow regulating valve 13 is provided in the circulating water tank 9, and an expansion valve 15 is provided on the top of the circulating water tank 9. When in use, the industrial refrigerator 10 is used to cool the coolant in the circulating water tank 9 to keep it at 0°C, and the booster pump 11 is used to extract the low-temperature coolant and inject it into the interlayer space of the cooling tank 2 and the jacketed reactor 1. The low-temperature coolant is heated after heat exchange with the cyanoester, and the heated coolant is injected back into the circulating water tank 9 through the reflux pipe for cooling. The structure is simple, the heat exchange efficiency is high, the coolant can be recycled, and the equipment operation and maintenance cost is low.

[0018] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A continuous high-efficiency cooling device for the production of cyanodiester, comprising a jacketed reactor and a cooling bin, characterized in that: The cooling bin is arranged on one side of the jacketed reactor, and an upper guide channel and a lower guide channel are symmetrically arranged in the vertical direction in the cooling bin, and a vertical multi-channel spiral heat exchange component is connected between the upper guide channel and the lower guide channel. A liquid guide pump is connected to the bottom discharge end of the jacketed reactor, and the outlet end of the liquid guide pump is connected to the lower guide channel. One end of the upper guide channel is connected to the jacketed reactor, and a water cooling circulation component is arranged on one side of the jacketed reactor and the cooling bin, and the water cooling circulation component is respectively connected to the jacketed reactor and the cooling bin.

2. A continuous high-efficiency cooling device for cyanodiester production according to claim 1, characterized in that: The vertical multi-channel spiral heat exchange component includes a support, a spiral heat exchange tube and a sealing joint. The support is fixed in the cooling bin. The spiral heat exchange tube is fixed by the support and the upper and lower ends are respectively connected to the upper guide channel and the lower guide channel through the sealing joint.

3. A continuous high-efficiency cooling device for producing cyanodiester according to claim 1, characterized in that: The water-cooling circulation component includes a circulating water tank, an industrial refrigerator and a booster pump. The circulating water tank is arranged on one side of the cooling tank. The industrial refrigerator is connected to the circulating water tank. The water inlet end of the booster pump is connected to the circulating water tank. The water outlet end of the booster pump is provided with a water supply pipe. The water supply pipe is respectively connected to the interlayer space of the jacketed reactor and the cooling tank. The interlayer space and the upper part of the cooling tank are connected to the circulating water tank through a return water pipe.

4. A continuous high-efficiency cooling device for producing cyanodiester according to claim 3, characterized in that: A one-way valve and a flow regulating valve are installed on the water supply pipeline.

5. A continuous high-efficiency cooling device for producing cyanodiester according to claim 3, characterized in that: A temperature probe is arranged in the circulating water bin.

6. A continuous high-efficiency cooling device for producing cyanodiester according to claim 3, characterized in that: An expansion valve is arranged on the top of the circulating water tank.

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