The invention discloses an integrated tobacco industry information security, operation and maintenance application platform system, which comprises an information security, operation and maintenance service management portal module, a centralized security control module, an informationized work management module and a business service management center module; the information security, operation and maintenance service management portal module is respectively connected with the business service management center module, the centralized security control module and the informationized work management module; the information security, operation and maintenance service management portal module mainly comprises a display module, a business module and an acquisition module, and the acquisition module is provided with an operating command interface and an external platform interface. The system can be used for centrally managing information security and IT (Information Technology) service, realizing the centralized management of accounts, authentication, authorization, audit and access, standardizing security, operation and maintenance management, increasing the quality of operation and maintenance, decreasing security risk, regularizing the behaviors of users, and facilitating to increase the professional levels of technicians.