64results about How to "Resume normal production" patented technology

The present invention is directed to methods and compositions for blocking the effect of the intronic inhibitory splicing region of intron 7 of the SMN2 gene. The compositions and methods of the instant invention include short oligonucleotide reagents (e.g., oligoribonucleotides) that effectively target sites in the SMN2 pre-mRNA, thereby modulating the splicing of SMN2 pre-mRNA to include exon 7 in the processed transcript. The short target regions are 8-mers and 5-mers and also include the identification of a single nucleotide base that is essential for initiating a long distance stearic inhibitory interactions as well as novel targets distant from intron 7 which block the intronic inhibitory splicing of the same. These short target regions and concomitant inhibitory blocking oligonucleotides are less expensive and easier to manufacture and are small enough to cross the blood brain barrier.

The invention discloses a remote operation and maintenance system for a textile machine, and an implementation method for the remote operation and maintenance system. The system comprises a textile machine IOT (Internet of Things) sensing system, a data transmission system, a cloud platform system and an operating system. The textile machine IOT sensing system comprises a textile machine device, aPLC controller, an industrial Internet intelligent transmission terminal connected with the PLC controller, a web camera installed on the textile machine device, a detection sensing device installedin textile machine device and a field actuator. The system achieves the real-time condition monitoring service, operation statistical analysis service, fault / abnormal condition alarm service, device failure rate distributed analysis service, online fault diagnosis service, remote maintenance and real-time video surveillance service of the textile machine device. The system realizes remote diagnosis and maintenance of the textile machine through taking the textile machine IOT sensing system and industrial cloud platform as the basis, centralizes and integrates the original piecemeal management,and promotes the whole life cycle management of equipment.

The invention discloses an equipment fault diagnosis method based on natural language processing and case-based reasoning. The equipment fault diagnosis method comprises the following steps: establishing a fault diagnosis knowledge base; Establishing a fault diagnosis case library; extracting diagnosis keywords from the fault diagnosis case library, establishing a fault diagnosis word library, extracting feature tags, and calculating weight matrixes of the feature tags; obtaining the similarity between the target fault case and the source fault case through the weight matrix, and then obtaining the matching degree of the target fault case and the source fault case; Obtaining a source fault case similar to the target fault case through the matching degree, and regarding the source fault case with the matching degree greater than a preset threshold as a similar case; And then making a response and evaluation to an actually occurring fault, and maintaining the case library according to anevaluation result. Through the method and the system, maintenance personnel can be helped to quickly and accurately determine the part and the reason of the equipment fault after the equipment faultoccurs, so that the improvement of the yield and the economic benefit of the equipment in the same time period is embodied.

The invention discloses a bow-type cultivation trunk molding method of lythraceae lagerstroemia trunks. The method mainly includes the following steps: (1) designing trunk molds, deconstructing the molds into single-plant technical atlases, and selecting a planting bed for cultivating nursery-grown plants; (2) manufacturing and installing a supporting net frame in the planting bed; (3) manufacturing and installing a bow-shaped cultivation trunk molding ladder frame on the supporting frame; (4) carrying out bud fixing and bud picking on the nursery-grown plants; (5) binding and fixing twigs on the bow-shaped cultivation trunk molding ladder frame; (6) unbinding and exchanging binding objects which are not beneficial for trunk growth; (7) carrying out multi-point nurse grafts on the bow-shaped trunks according to molding design; and (8) cultivating in a healing mode, constructing crowns, the trunks and branches, and forming the target molds. The bow-type cultivation trunk molding method of the lythraceae lagerstroemia trunks is creative. Moreover, the nurse grafts can be carried out on single plants of the certain number to obtain the molded trunks, molding time is shortened, and characters, patterns or three-dimensional bodies can also be molded on planes or curved surfaces of the trunks.

The present invention includes nuclear fertility restorer genes, proteins encoded by those genes and transgenic plants and plant cells containing those genes. More particularly, the nuclear fertility restorer genes can be used to restore fertility in cytoplasmic male-sterile plants such as Brassica napus. Preferably, the nuclear fertility restorer genes are used with the Ogura (ogu) CMS system in Brassica napus.

The invention discloses a system for monitoring the running of an oil extractor in an oil field. A motor protector is arranged at a driving motor of the oil extractor, and a host computer is arranged in a centralized monitoring center, wherein wireless signal transmitting / receiving units are arranged on the motor protector; and the host computer compares received state changing rules of running current parameters of the driving motor, remotely reads the running current parameters of the driving motor to perform comparison, and judges various faults. Preset values and preset changing rules of the running current parameters of the driving motor can be obtained from curves in an oil well indicator diagram or from load analyses in a four-stroke process of the oil extractor. A 'one-to-many' wireless signal transmission network structure is adopted between a wireless signal retransmitting / relaying unit and each wireless signal transmitting / receiving unit; and wireless signals of a plurality of the wireless signal transmitting / receiving units are uploaded to the host computer. A GPRS wireless communication network is adopted between the wireless signal retransmitting / relaying unit and the host computer to perform data transmission so as to transmit the wireless signals to the host computer.

The present invention is directed to compositions targeting the signal peptidase complex and methods of use in treating and preventing flavivirus infection.

Disclosed are devices for urine voiding postponement, and methods for treating conditions such as central diabetes insipidus, enuresis, nocturia, urinary frequency or incontinence. The devices deliver a desmopressin flux through the skin of a patient in a low dose amount just necessary to achieve a desired anti-diuretic effect without undesirable side effects such as hyponatremia. The devices are designed to permit a state of normal urinary production to return quickly after the desmopressin flux is terminated.

The invention relates to a pilot milling tool for repairing a casing by utilizing a pilot milling cone made of high-strength cemented alloy milling materials and a method thereof. The structure of thepilot milling cone comprises a connector, a body, milling materials on the body, a circulating water channel, a circulating water hole, a pilot hole and a central hole. The casing repairing method proposes the casing repairing method for using serialized pilot milling cone to mill and get through the channel by the guiding function of a cone pilot part at the front end and the correcting functionof a cylinder part at the back end and can effectively prevent damage to the casing or ejection of the milling cones from the casing during the milling construction. The casing repairing method and the tool thereof are applicable to casing-damaged wells which are severely bended and dislocated.

The invention discloses a comprehensive mining technology of a drowned well, comprising the step 1: stratum unblocking pretreatment prior to water plugging; step 2: shallow plugging; step 3: deep plugging adjustment; and step 4: hydraulic deep penetration perforating and oil production recovery of an oil well. According to the characteristics of the drowned well, multiple mature technologies are organically comprehensively applied, with the combination of first dredging and subsequent plugging, the problem that no oil is produced after plugging is effectively solved. By first shallow plugging and subsequent deep plugging adjustment and in combination with hydraulic deep penetration perforating, the period of validity of mining is effectively prolonged and the input-output ratio is improved.

Provided are methods and compositions for a combination therapy for liver disorders such as hepatocellular carcinoma. Also provided is a method for determining the effectiveness of therapy involving tyrosine kinase inhibitors such as sorafenib. The method comprises determining the status of PD-1 on T cells, and based on a change in the level of PD-1 on certain cells, a determination of the effectiveness of the tyrosine kinase, and an indication for a combination therapy comprising a lower dose of tyrosine kinase inhibitor and a PD-1 inhibitor can be made.

Disclosed is a method for pressing a low-pressure oil and gas well. The method comprises the steps that firstly, alkaline guanidine gum liquid with the appropriate concentration and oil-soluble temporary plugging agents are prepared according to the well conditions (wellbore volume, gas production rate and the like); the oil-soluble temporary plugging agents and the guanidine gum liquid are mixed and then sufficiently and evenly stirred, and the temporary plugging agents are suspended in the guanidine gum liquid; the matched process, a ground pipeline and equipment are adopted to feed the mixture of the oil-soluble temporary plugging agents and the guanidine gum liquid into a stratum; the matched pipe column process is adopted to achieve the aims that the guanidine gum liquid with the temporary plugging agents can block and shield the stratum, leakage of well pressing liquid injected in a shaft is avoided, meanwhile, alkaline guanidine gum liquid has the better air-tight sealing performance and better safety for acid gas (hydrogen sulfide, carbon dioxide and the like), the shaft is filled with the alkaline guanidine gum liquid, the stratum gas is prevented from entering the shaft, it is ensured that well pressing succeeds, and the subsequent well repairing operation is facilitated. The method for pressing the low-pressure oil and gas well has the advantages that a near well zone nearby a shot hole is effectively blocked, the well pressing liquid is prevented from leaking, and entering the stratum, the stratum gas is prevented from entering the shaft, and it is ensured that the well repairing operation is smoothly carried out.

The invention relates to the technical field of oilfield workover sand control operation, in particular to a flexible first-time sand control sandblasting technique pipe. Multiple slotted screens of the pipe are mutually connected through flexible connectors to form a slotted screen string, each flexible connector comprises a flexible connector lower adaptor and a flexible connector upper adaptor which are connected and are locked through a flexible connector locking screw, the lower end of the slotted screen string is connected with a ball seat with the lower end connected with a guiding shoe nib, the upper end of the slotted screen string is connected with a hanger body through the flexible connectors, a hanger sealing rubber sleeve and a rubber sleeve distance ring are sleeved on the hanger body, a compression rubber sleeve adaptor is disposed at the upper end of the rubber sleeve distance ring and is in screwed connection with the hanger body, and the upper end of the compression rubber sleeve adaptor is in screwed connection with a hanger spindle and fixed through a shear pin. By the technique pipe, first-time success rate of sand control of large-curvature wells is improved, sand control cost is lowered, sand control time effectiveness is improved, and production of sand control wells is resumed timely.

The invention discloses a two-dimensional automatic loading-unloading winding machine. The two-dimensional automatic loading-unloading winding machine comprises assembly lines,a recycling assembly line,Y-axis moving modules,finger clips,a taking and left-right moving module,a staggered cylinder,a reduction motor,a loading-unloading rack,a loading-unloading moving cylinder,an up-down fixing mechanism,a forward-backward moving mechanism,a bottom plate,flying forks,rotary main shafts,a sheath cylinder,a clamping and moving cylinder,a closed-loop stepping motor,a servo motor,wire guide rods,a clamping cylinder,a pulling cylinder,a top fork moving cylinder,a mechanism for detecting whether there are rotors or no,transposition rods,a transposition motor,a lead screw base,u-turn main shaft mechanisms,a transposition rod up-down moving cylinder,u-turn fixing devices and limiting plates. According to the two-dimensional automatic loading-unloading winding machine,the total rotor process from vacant rotors to completion of line coiling to completion of line hanging is fully automatically achieved without people,the work quality is improved,manual work is reduced,and the machine can have various work modes of separated assembling,respective debugging and combined working,and can be suitable for different working scenes.

The invention relates to a Chinese medicinal preparation for treating intractable hyperplastic mastitis and a preparation method thereof. The preparation is prepared from the following raw materials in part by weight: 100 parts of astragalus, 60 parts of Chinese angelica, 60 parts of curcuma, 50 parts of root of red-rooted salvia, 40 parts of Szechuan lovage rhizome, 40 parts of red peony root, 40 parts of gleditsia sinensis sting, 20 parts of shell, 60 parts of gardenia, 30 parts of rhubarb, 60 parts of pig nail and 30 parts of cowherb seed. The preparation method comprises the following steps of: sauting the pig nail, soaking into edible rice vinegar, fishing out, drying and grinding into powder for later use; grinding the astragalus, the Chinese angelica, the curcuma, the root of red-rooted salvia, the Szechuan lovage rhizome, the red peony root, the gleditsia sinensis sting, the shell, the gardenia, the rhubarb and the cowherb seed into powder for later use, mixing and stirring the powdery raw materials uniformly, bagging, sealing, and thus obtaining the Chinese medicinal preparation. The Chinese medicinal preparation has obvious advantages of diminishing swelling, removing stasis, softening mammary tissues, eliminating edema and the like, has an obvious treatment effect on mammary tissue hyperplasia and repeated attack of mastitis, and has obvious effects of recovering the function of mammary gland and recovering production.

The invention discloses a cable calibrating instrument and a cable calibrating method. The cable calibrating instrument comprises a calibrating transmitter and a calibrating receiver; the calibrating transmitter comprises a frequency generation unit and a first power supply unit, wherein the first power supply unit is electrically connected with the frequency generation unit; the calibrating receiver comprises a frequency induction receiving unit, a second display unit and a second power supply unit which is electrically connected with the frequency induction receiving unit and the second display unit respectively, and the frequency induction receiving unit is connected with the second display unit; during calibration, one end of a to-be-calibrated cable core is connected with the calibrating transmitter, and the other end of the to-be-calibrated cable core is connected with the frequency induction receiving unit. According to the cable calibrating instrument in the invention, multiple cables can be calibrated at the same time, so that constructors are reduced, and the calibration efficiency is improved.

The invention discloses a gas well shaft compound blockage treatment method. The method comprises the following specific steps that 1, shaft blockage is verified through hot water, the hot water is pumped into a shaft from a well mouth, the displacement in the pumping process is smaller than or equal to 1m< 3 > / min, the pump pressure change condition is observed in the pumping process, and the shaft blockage throttling severity degree is judged; 2, if the pump pressure change condition is that the pump pressure is gradually decreased in the hot water pumping process in the step 1, a blockage removal agent injection soaking process is adopted for blockage removal treatment; and 3, if the pump pressure change condition is that the pump pressure is kept stable or even increased in the hot water pumping process in the step 1, a coiled tubing is adopted for cyclic flushing firstly, and then the blockage removal agent injection soaking process is adopted for blockage removal treatment.

The invention provides a temporary plugging well killing fluid for fractured reservoirs and application and a preparation method thereof. The temporary plugging well killing fluid comprises a base solution and degradable shape memory polymer particles, the base solution is a composite gel, the degradable shape memory polymer particles are composed of polymers with different deformation recovery amounts, and the degradable shape memory polymer particles are injected into a reservoir stratum through a base solution carrying pump, enter a fractured reservoir stratum, expand due to temperature response, and recover the shape. Temporary plugging and well killing can be achieved for a fractured gas well, low-damage well repair of low-pressure-coefficient and ultralow-pressure-coefficient and low-yield gas wells can be met, the fluidity is good at the ground temperature, and pumping injection is easy. After entering the fractured reservoir, the pressure bearing performance is rapidly improved, the subsequent clear water workover fluid loss is greatly reduced, the operation safety is ensured, and the reservoir damage is reduced. Shape memory polymer particles with different degradation periods can be selected according to the operation requirements, and can be completely degraded after the operation is completed, and the flow-back and the production recovery are fast.

The invention provides a parallel power supplying method of electrolytic aluminum different-power-supply-point direct-current sides, and belongs to the technical field of electric power system operation and control. The method is used for convention between a public power grid and an autonomous power grid. The public power grid and the autonomous power grid are connected with different alternating-current power supplying buses. The different alternating-current power supplying buses are provided with sectionalized change-over switches. Rectification units are arranged between the different alternating-current power supplying buses and an electrolytic aluminum direct-current bus. Switch stations are arranged between the autonomous power grid and the alternating-current power supplying buses. Power substations are arranged on the connecting ends between the switch station and the alternating-current power supplying buses.

The invention discloses a pipeline fisher. The pipeline fisher comprises a body and a drill rod; the head of the body is a cone, and the tail of the body is fixedly connected with the drill rod; and symmetrical inclined guide hole channels are arranged in the connection position of the body and the drill rod and communicate with the inside of the drill rod. The invention further discloses a pipeline fishing method. The method includes the following steps that firstly, the drill rod of the pipeline fisher is connected with a driving drill rod, and the upper portion of the driving drill rod is connected with a ground water delivery device; then the pipeline fisher is put down into a to-be-fished pipeline in a well through a lifting mechanism, broken alloys or / and iron sand are cast from a plug hole in an elbow of the ground water delivery device, a bolt is screwed at the plug hole, and a pump is started to flush the hole; and finally, the fisher is lifted through the lifting mechanism, and then to-be-fished pipeline is fished out. The pipeline fisher is easy to fabricate and low in cost; and the fishing method is simple and effective, and the pipeline (well casing) dropped into a drilled hole can be conveniently, rapidly and effectively fished.

The invention discloses a hydraulic hoisting device for replacing a pipe column and a wellhead part. The hydraulic hoisting device is provided with a hoisting system and a connecting mechanism, wherein the hoisting system is connected with a wellhead device to be replaced through the connecting mechanism; the hydraulic hoisting device further comprises a pipe column locking device which is mainly used for locking a downhole pipe column connected with the wellhead device; a method comprises the following steps: 1) mounting the hoisting system; 2) detaching the wellhead device; 3) assembling a wellhead four-way joint. By adopting the hydraulic hoisting device for replacing the pipe column and the wellhead part, wellhead replacement is carried out, and a pipe arrangement step is saved; the downhole pipe column only needs to be partially lifted, and then the downhole pipe column is locked by utilizing the matched pipe column locking device; then the whole weight of the downhole pipe column is transferred to an outer pipe, so that a wellhead can be replaced under the condition that the whole downhole pipe column is not detached, and furthermore, the working efficiency of wellhead maintenance work is effectively improved, and the maintenance time is reduced; the time consumption in a replacement process is only no more than 25 percent that of the prior art.

The invention relates to a feed-adjustable premixed concentrate nozzle which comprises an oxygen supply pipe and a scattering air pipe, wherein the oxygen supply pipe and the scattering air pipe are vertically arranged and are sleeved in order, and the pipe cores of the oxygen supply pipe and the scattering air pipe are overlapped. The outer wall of the scattering air pipe is sleeved with a feed box, and a batch charging port used for inclined downward batch charging is formed in the side face of the feed box. Splitting plates are vertically arranged on the inner side of the feed box and are used for dividing the batch charging port into a plurality of batch charging branch ports, and the width of the batch charging branch ports is regulated by the rotation of the splitting plates. Batch charging channels corresponding to the batch charging branch ports lead mineral aggregates to the specified material chambers in the feed box. The width of all the batch charging branch ports is regulated by the rotation of the splitting plates, so that the batch charging amount of each batch charging branch port is controlled, and further the batch charging amount of the specified material chambers in the feed box can be controlled. The feed-adjustable premixed concentrate nozzle realizes uniform feeding on each point direction in a flash furnace and effectively solves the problem that the burning temperature in the flash furnace is unbalanced.

The invention discloses an intelligent scheduling system and method for a steelmaking production process. The scheduling system comprises an ERP system, a database server, a real-time monitoring system, a client and an application server. The ERP system is in communication connection with the database server, the output end of the real-time monitoring system is in communication connection with theinput end of the database server, the output end of the database server is in communication connection with the input end of the client, and the database server is in communication connection with the application server. According to the invention, the problems of inconsistent coordination of procedures before and after a production site and delayed mastering of real-time time information by technical management personnel are solved.

The invention discloses a method for rapidly eliminating nodules on the surfaces of furnace rollers. The method comprises the steps that S1, it is found that roller marks appear on the surface of a steel belt; S2, the positions of the furnace rollers carrying the nodules are locked; S3, a console is used for controlling the adjacent furnace rollers in a roller set in the area where the nodules are located to rotate in a differential mode or the single furnace roller to rotate in a variable acceleration mode; and S4, whether the roller marks on the steel belt disappear or not is observed, if so, production recovers, and if not, returning is conducted to execute the step S3. According to the method, the nodules in a furnace can be rapidly eliminated without starting the continuous annealing furnace, the nodules are rapidly treated, continuous production is guaranteed, and the nodule treatment cost is reduced.

Disclosed is a method for pressing a low-pressure oil and gas well. The method comprises the steps that firstly, alkaline guanidine gum liquid with the appropriate concentration and oil-soluble temporary plugging agents are prepared according to the well conditions (wellbore volume, gas production rate and the like); the oil-soluble temporary plugging agents and the guanidine gum liquid are mixed and then sufficiently and evenly stirred, and the temporary plugging agents are suspended in the guanidine gum liquid; the matched process, a ground pipeline and equipment are adopted to feed the mixture of the oil-soluble temporary plugging agents and the guanidine gum liquid into a stratum; the matched pipe column process is adopted to achieve the aims that the guanidine gum liquid with the temporary plugging agents can block and shield the stratum, leakage of well pressing liquid injected in a shaft is avoided, meanwhile, alkaline guanidine gum liquid has the better air-tight sealing performance and better safety for acid gas (hydrogen sulfide, carbon dioxide and the like), the shaft is filled with the alkaline guanidine gum liquid, the stratum gas is prevented from entering the shaft, it is ensured that well pressing succeeds, and the subsequent well repairing operation is facilitated. The method for pressing the low-pressure oil and gas well has the advantages that a near well zone nearby a shot hole is effectively blocked, the well pressing liquid is prevented from leaking, and entering the stratum, the stratum gas is prevented from entering the shaft, and it is ensured that the well repairing operation is smoothly carried out.

The invention discloses a Yikangbao traditional Chinese medicine mixture, and relates to the field of diabetes treatment medicaments. The Yikangbao traditional Chinese medicine mixture can improve pancreas and a peripheral blood circulation system, increase blood nourishing energy value, repair smooth muscle on the inner wall of blood vessels and clean attachments on the blood vessel wall, restorepancreas to produce enough insulin, and cure a symptom that the pancreas cannot produce enough insulin.

The invention discloses a secondary recovery method for stagnant ore blocks. The method comprises the following steps: a new well drilling, single well channelling, water injection fracturing, channel expanding, mounting of an oil-immersed pump and secondary recovery. According to the method provided by the invention, a large amount of stagnant bittern in a waste solution cavity is directly drawn, in a later period, and fresh water is supplemented through a relatively good old well in a subsidence area to dissolve the stagnant ore blocks in the subsidence area, so that the recovery ratio of mineral resources is increased. An aquifer in the subsidence area is effectively drained or the water level of the aquifer in the subsidence area is effectively reduced, therefore, bittern on farmlands can be controlled basically and loss of the agricultural industry is reduced.