Cryopreservation tube for umbilical cord hematopoietic stem cells

Abstract

The utility model discloses a cryopreservation tube for umbilical cord hematopoietic stem cells, which relates to the technical field of medical supplies and comprises a bottom plate, bases are symmetrically and fixedly mounted at the lower end of the bottom plate, an auxiliary component is mounted at the upper end of the bottom plate, and a cryopreservation tube is movably inserted into the auxiliary component. And a sealing mechanism is mounted at the top of the cryopreservation tube. According to the sealing mechanism, under the cooperation of the sealing cover, the sealing plug, the outer ring, the supporting plate, the sealing ring, the first threaded section and the outer threaded pipe, a user can screw the first thread on the inner side of the sealing ring into the outer side of the outer threaded pipe, so that the sealing plug can enter the cryopreservation pipe, and then the top of the cryopreservation pipe can be sealed; the gap between the sealing cover and the cryopreservation tube can be sealed, the using effect of the cryopreservation tube is improved, and then stem cell substances contained in the cryopreservation tube can be prevented from being polluted or leaked.

Description

Technical Field

[0001] The utility model relates to the technical field of medical supplies, in particular to a cryopreservation tube for umbilical cord hematopoietic stem cells. Background Art

[0002] Umbilical cord blood stem cells are primitive cells with differentiation potential in umbilical cord blood. They have the ability to self-renew and proliferate, and can differentiate into various cells or tissues under the influence or induction of specific factors. Umbilical cord blood hematopoietic stem / progenitor cells have a high degree of self-renewal or replication ability, can maintain a constant number of stem cells, and can further differentiate into various lineage progenitor cells and mature cells. CD34 antigen is the main marker for separating and purifying hematopoietic stem / progenitor cells. The CD34+ cell population in umbilical cord blood is higher in quantity, quality and proliferation ability than peripheral blood. The hematopoietic stem / progenitor cells in umbilical cord blood have more primitive and stronger proliferation and differentiation abilities. In recent years, umbilical cord blood hematopoietic stem cell transplantation has developed into a high-tech biological treatment method, which is widely used in the treatment of many diseases, including malignant blood diseases, autoimmune diseases, severe immunodeficiency, etc., and has been clinically proven to have certain therapeutic effects.

[0003] Cryopreservation is the key to cord blood storage and hematopoietic stem cell transplantation. Therefore, cord blood stem cells need to be placed in cryopreservation tubes for storage.

[0004] The existing technology has the following problems:

[0005] In actual use, the existing cryopreservation tubes have poor sealing properties, which may cause the stem cell materials contained therein to be contaminated or leaked, thereby causing the stem cells to lose their function, thereby reducing the practicality of the cryopreservation tubes. Utility Model Content

[0006] In order to solve the above technical problems, the technical solution adopted by the utility model is:

[0007] A cryopreservation tube for umbilical cord hematopoietic stem cells comprises a bottom plate, a base is symmetrically fixedly mounted on the lower end of the bottom plate, an auxiliary component is mounted on the upper end of the bottom plate, a cryopreservation tube is movably inserted inside the auxiliary component, and a sealing mechanism is mounted on the top of the cryopreservation tube.

[0008] Preferably: the auxiliary component includes a pipe sleeve, the lower end of the pipe sleeve is fixedly connected to the upper end of the base plate, a cushion 1 is fixedly installed on the inner bottom end of the pipe sleeve, two groups of protective rings are installed on the inner wall of the pipe sleeve, and a cushion 2 is fixedly installed on the inner walls of the two groups of protective rings.

[0009] Preferably, the cushion is semicircular.

[0010] Preferably, the outer side of the protective ring is fixedly connected to the inner wall of the pipe sleeve.

[0011] Preferably: the sealing mechanism includes a sealing cover, the lower end of the sealing cover is movably connected to the upper end of the freezing tube, a sealing plug is fixedly installed in the middle of the lower end of the sealing cover, an outer ring is fixedly connected to the outside of the lower end of the sealing cover, the end faces of the sealing cover are symmetrically fixedly installed with support plates, the lower end of the support plate is installed with a sealing ring, the inner wall of the sealing ring is provided with a threaded section, and an externally threaded tube is fixedly sleeved on the outer upper side of the freezing tube.

[0012] Preferably, the lower end of the support plate is fixedly connected to the upper end surface of the sealing ring.

[0013] Preferably, the externally threaded pipe is threadedly connected to the threaded section.

[0014] Preferably, the bottom end of the cryogenic tube matches with the first cushion, the second cushion fits with the outer wall of the lower end of the cryogenic tube, and the interior of the upper end of the cryogenic tube matches with the sealing plug and is movably connected.

[0015] Due to the adoption of the above technical solution, the utility model has achieved the following technical progress compared with the prior art:

[0016] 1. The utility model provides a cryopreservation tube for umbilical cord hematopoietic stem cells, which can be used repeatedly through auxiliary components, through the cooperation of pipelines, soft pad 1, protective rings and soft pad 2, and can make the cryopreservation tube more stable when placed.

[0017] 2. The utility model provides a cryopreservation tube for umbilical cord hematopoietic stem cells. Through a sealing mechanism, through the cooperation of a sealing cover, a sealing plug, an outer ring, a support plate, a sealing ring, a threaded section 1, and an externally threaded tube, a user can use a thread 1 on the inner side of the sealing ring to screw into the outer side of the externally threaded tube, so that the sealing plug can enter the interior of the cryopreservation tube, and then the top of the cryopreservation tube can be sealed. Through the provision of a sealing gasket, the gap between the sealing cover and the cryopreservation tube can be sealed, thereby improving the use effect of the cryopreservation tube and preventing the stem cell material contained therein from being contaminated or leaked. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the structure of a cryopreservation tube for umbilical cord hematopoietic stem cells of the utility model;

[0019] Figure 2 It is a structural schematic diagram of the cryopreservation tube of the utility model;

[0020] Figure 3 It is a structural schematic diagram of the auxiliary component of the utility model;

[0021] Figure 4 It is a structural schematic diagram of the sealing mechanism of the utility model.

[0022] In the figure: 1. bottom plate; 2. base; 3. auxiliary component; 4. cryogenic tube; 5. sealing mechanism; 31. tube sleeve; 32. cushion 1; 33. protective ring; 34. cushion 2; 51. sealing cover; 52. sealing plug; 53. outer ring; 54. support plate; 55. sealing ring; 56. threaded section 1; 57. external threaded tube. DETAILED DESCRIPTION

[0023] The present invention is further described in detail below in conjunction with the embodiments:

[0024] like Figure 1-4 As shown, the utility model provides a cryopreservation tube for umbilical cord hematopoietic stem cells, comprising a bottom plate 1, a base 2 is symmetrically fixedly installed at the lower end of the bottom plate 1, an auxiliary component 3 is installed at the upper end of the bottom plate 1, a cryopreservation tube 4 is movably inserted inside the auxiliary component 3, and a sealing mechanism 5 is installed on the top of the cryopreservation tube 4.

[0025] The bottom end of the cryotube 4 matches with the cushion 1 32 , the cushion 2 34 fits with the outer wall of the lower end of the cryotube 4 , and the inner part of the upper end of the cryotube 4 matches with the sealing plug 52 and is movably connected.

[0026] The auxiliary component 3 can be reused conveniently and can make the cryogenic tube 4 more stable when placed. Through the sealing mechanism 5, the user can use the inner thread of the sealing ring 55 to screw into the outer side of the external threaded tube 57, so that the sealing plug 52 can enter the interior of the cryogenic tube 4, and then the top of the cryogenic tube 4 can be sealed. Through the setting of the sealing gasket, the gap between the sealing cover 51 and the cryogenic tube 4 can be sealed, thereby improving the use effect of the cryogenic tube 4 and preventing the stem cell material contained therein from being contaminated or leaked.

[0027] like Figure 3 As shown, the auxiliary component 3 includes a pipe sleeve 31, the lower end of the pipe sleeve 31 is fixedly connected to the upper end of the base plate 1, a cushion 1 32 is fixedly installed on the inner bottom end of the pipe sleeve 31, two groups of protective rings 33 are installed on the inner wall of the pipe sleeve 31, and soft cushions 2 34 are fixedly installed on the inner walls of the two groups of protective rings 33.

[0028] The cushion 1 32 is semicircular.

[0029] The outer side of the protection ring 33 is fixedly connected to the inner wall of the pipe sleeve 31 .

[0030] By providing the soft pad 1 32 and the soft pad 2 34, the collision damage of the cryopreservation tube 4 when it is placed can be reduced.

[0031] like Figure 4As shown, the sealing mechanism 5 includes a sealing cover 51, the lower end of the sealing cover 51 is movably connected to the upper end of the cryopreservation tube 4, a sealing plug 52 is fixedly installed in the middle of the lower end of the sealing cover 51, an outer ring 53 is fixedly connected to the outer part of the lower end of the sealing cover 51, and support plates 54 are symmetrically fixedly installed on the end faces of the sealing cover 51, a sealing ring 55 is installed at the lower end of the support plate 54, a threaded section 56 is provided on the inner wall of the sealing ring 55, and an external threaded tube 57 is fixedly sleeved on the outer part of the upper side of the cryopreservation tube 4.

[0032] The lower end of the support plate 54 is fixedly connected to the upper end surface of the sealing ring 55 .

[0033] The external threaded pipe 57 is threadedly connected to the threaded section 1 56 .

[0034] The following is a detailed description of the working principle of the cryopreservation tube for umbilical cord hematopoietic stem cells.

[0035] like Figure 1-4 As shown, when the cryopreservation tube for umbilical cord hematopoietic stem cells is used, the stem cell material can be stored in the cryopreservation tube 4, and then the sealing ring 55 can be sleeved on the top of the cryopreservation tube 4, and the threaded section 1 56 and the external threaded tube 57 are in contact. Then, the sealing cover 51 can be rotated, so that the sealing cover 51 can drive the sealing ring 55 to rotate through the support plate 54, and then drive the threaded section 1 56 to rotate on the external threaded tube 57, so that the sealing ring 55 is screwed into the outside of the external threaded tube 57, and the sealing ring 55 will drive the sealing cover 51 downward when being screwed in, so that the sealing plug 52 is inserted into the cryopreservation tube 4. , and by setting the sealing gasket, the gap between the sealing plug 52 and the cryogenic tube 4 can be sealed, so as to improve the use effect of the cryogenic tube 4, and thus prevent the stem cell material contained therein from being contaminated or leaking; and when placing the cryogenic tube 4, the bottom end of the cryogenic tube 4 can be inserted into the inside of the pipeline, so that the tube sleeve 31 is sleeved on the cryogenic tube 4, and at the same time, the bottom end of the cryogenic tube 4 is fitted with the soft pad 1 32, and the soft pad 2 34 on the inner side of the protective ring 33 is fitted with the outer wall of the lower end of the cryogenic tube 4, so that the cryogenic tube 4 can be placed more stably and the cryogenic tube 4 can be protected.

[0036] The above generally describes the present invention in detail, but it is obvious to a person skilled in the art that some modifications or improvements can be made to the present invention. Therefore, modifications or improvements that do not deviate from the spirit of the present invention are within the scope of protection of the present invention.

Claims

1. A cryopreservation tube for umbilical cord hematopoietic stem cells, comprising a bottom plate (1), the lower end of which is symmetrically fixed with a base (2), characterized in that: An auxiliary component (3) is installed at the upper end of the bottom plate (1), a cryogenic tube (4) is movably inserted into the interior of the auxiliary component (3), and a sealing mechanism (5) is installed at the top of the cryogenic tube (4).

2. A cryopreservation tube for umbilical cord hematopoietic stem cells according to claim 1, characterized in that: The auxiliary component (3) comprises a pipe sleeve (31), the lower end of the pipe sleeve (31) is fixedly connected to the upper end of the bottom plate (1), a cushion 1 (32) is fixedly installed on the inner bottom end of the pipe sleeve (31), two groups of protective rings (33) are installed on the inner wall of the pipe sleeve (31), and a cushion 2 (34) is fixedly installed on the inner walls of the two groups of protective rings (33).

3. A cryopreservation tube for umbilical cord hematopoietic stem cells according to claim 2, characterized in that: The cushion (32) is semicircular.

4. A cryopreservation tube for umbilical cord hematopoietic stem cells according to claim 3, characterized in that: The outer side of the protective ring (33) is fixedly connected to the inner wall of the pipe sleeve (31).

5. A cryopreservation tube for umbilical cord hematopoietic stem cells according to claim 1, characterized in that: The sealing mechanism (5) comprises a sealing cover (51), the lower end of the sealing cover (51) is movably connected to the upper end of the freezing tube (4), a sealing plug (52) is fixedly installed in the middle of the lower end of the sealing cover (51), an outer ring (53) is fixedly connected to the outer part of the lower end of the sealing cover (51), and a support plate (54) is symmetrically fixedly installed on the end surface of the sealing cover (51), a sealing ring (55) is installed at the lower end of the support plate (54), and a threaded section (56) is provided on the inner wall of the sealing ring (55), and an external threaded tube (57) is fixedly sleeved on the outer part of the upper side of the freezing tube (4).

6. A cryopreservation tube for umbilical cord hematopoietic stem cells according to claim 5, characterized in that: The lower end of the support plate (54) is fixedly connected to the upper end surface of the sealing ring (55).

7. A cryopreservation tube for umbilical cord hematopoietic stem cells according to claim 6, characterized in that: The externally threaded pipe (57) is threadedly connected to the threaded section 1 (56).

8. A cryopreservation tube for umbilical cord hematopoietic stem cells according to claim 2, characterized in that: The bottom end of the cryotube (4) matches with the cushion 1 (32), the cushion 2 (34) fits with the outer wall of the lower end of the cryotube (4), and the upper end of the cryotube (4) matches with the sealing plug (52) and is movably connected.

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