Dapagliflozin preparation reaction device with protection function

Abstract

The utility model belongs to the field of medicine preparation protection devices, and particularly relates to a dapagliflozin preparation reaction device with a protection function, which comprises a reaction kettle main body, the top of the reaction kettle main body is fixedly connected with a flange connecting disc, and the upper part of the flange connecting disc is fixedly connected with a top cover; through the structural design of a liquid inlet and a liquid outlet formed in the surface of the shell, drainage of a stock solution is facilitated, sliding rods are slidably connected into lantern rings on the two sides of a through pipe in a sleeved mode, springs are connected to the positions, close to the upper portions of the lantern rings, of the surfaces of the sliding rods in a sleeved mode, and when a violent reaction occurs in the device for material flushing, a reaction solution in a guide pipe backflushes a cover plate; secondly, the other end of the guide pipe is located at the position, close to the center point, of the bottom of the reaction kettle main body, so that the effect that the reaction solution flows into the reaction kettle main body from the inner bottom surface of the reaction kettle main body is achieved; the condition of violent reaction caused by large drop of raw materials dropped into the device is reduced.

Description

Technical Field

[0001] The utility model relates to the field of drug preparation protection devices, in particular to a reaction device for preparing dapagliflozin with a protection function. Background Art

[0002] During the preparation process of dapagliflozin, a reactor is required to mix the drug solution. When the amount of drug solution is added incorrectly, the drug solution in the inner cavity of the reactor is prone to violent reaction and material rushing, which will cause danger to operators and equipment. Therefore, a reaction device with protective function is needed.

[0003] The existing reaction device is not easy to timely and automatically cut off the supply of the reaction solution when the material rush occurs in the device, and it is not easy to achieve the effect of slowly injecting the reactive solution, which may cause the problem of low device safety.

[0004] Therefore, in order to solve the above problems, a reaction device for preparing dapagliflozin with a protective function is proposed. Utility Model Content

[0005] In order to remedy the problems in the prior art, the utility model proposes a reaction device for preparing dapagliflozin with a protective function.

[0006] The technical solution adopted by the utility model to solve its technical problems is: the utility model describes a reaction device for preparing dapagliflozin with a protective function, comprising a reactor body, a flange connecting plate fixedly connected to the top of the reactor body, a top cover fixedly connected to the top of the flange connecting plate, a fixed block fixedly connected to the top of the top cover, a motor fixedly installed on the surface of the fixed block, a rotating shaft fixedly connected to the output end of the motor, a stirring rod fixedly provided at the bottom end of the rotating shaft, a flat plate fixedly installed on the side of the reactor body, a protective mechanism fixedly installed on the surface of the flat plate, and a feed valve snap-fitted onto the top of the protective mechanism.

[0007] Preferably, the protection mechanism comprises a shell, a liquid inlet is provided at the top of the shell, a liquid outlet is provided at the bottom of the shell, and a through pipe is provided at a position of the inner wall of the shell near the top.

[0008] Preferably, collars are fixedly connected to both sides of the through pipe, a slide rod is slidably installed inside the collar, a cover plate is fixedly connected to the bottom of the slide rod, and the size of the cover plate matches the size of the through pipe.

[0009] Preferably, a spring is sleeved on the surface of the sliding rod close to the upper part of the collar, and a sealing ring is embedded on the surface of the cover plate.

[0010] Preferably, a connecting block is fixedly connected to the inner wall of the reactor body, a conduit is fixedly connected to the surface of the connecting block, a protective mechanism is snap-fitted onto one end of the conduit, and the other end of the conduit is located near the center point at the bottom of the reactor body.

[0011] Preferably, a discharge valve is fixedly connected to the bottom of the reactor body, and a support frame is fixedly connected to the bottom surface of the reactor body.

[0012] The utility model is beneficial in that:

[0013] 1. The utility model is convenient for draining the stock solution through the structure design of the liquid inlet and the liquid outlet opened on the surface of the shell. The sliding rod is slidably sleeved in the sleeve rings on both sides of the through pipe, and the surface of the sliding rod is sleeved with a spring near the upper part of the sleeve ring. When the device reacts violently and material rushes, the reaction solution in the conduit will rebound to the cover plate, so that the cover plate squeezes the through pipe to cut off the supply of the reaction solution, thereby reducing the intensity of the solution rushing in the device and improving the safety of the device.

[0014] 2. The utility model realizes the effect of allowing the reaction solution to flow into the device from the bottom surface through the structural design that the other end of the conduit is located near the center point of the bottom of the reactor body, reduces the situation where the raw material drips into the device and causes a large drop in the drop to cause a violent reaction, and improves the safety of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0016] Figure 1 This is a schematic diagram of the main structure of the reactor of the utility model;

[0017] Figure 2 This is a schematic diagram of the stirring rod structure of the utility model;

[0018] Figure 3 It is a schematic diagram of the catheter structure of the utility model;

[0019] Figure 4 It is a schematic diagram of the protection mechanism structure of the utility model.

[0020] In the figure: 1. Reactor body; 2. Support frame; 3. Flange connection plate; 4. Top cover; 5. Fixing block; 6. Motor; 7. Rotating shaft; 8. Stirring rod; 9. Connecting block; 10. Conduit; 11. Flat plate; 12. Protective mechanism; 121. Shell; 122. Liquid inlet; 123. Liquid outlet; 124. Through pipe; 125. Ring; 126. Sliding rod; 127. Cover plate; 128. Spring; 129. Sealing ring; 13. Feed valve; 14. Discharge valve. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0022] See also Figure 1-Figure 4 As shown, a reaction device for preparing dapagliflozin with a protective function comprises a reactor body 1, a flange connection plate 3 is fixedly connected to the top of the reactor body 1, a top cover 4 is fixedly connected to the top of the flange connection plate 3, a fixing block 5 is fixedly connected to the top of the top cover 4, a motor 6 is fixedly installed on the surface of the fixing block 5, a rotating shaft 7 is fixedly connected to the output end of the motor 6, a stirring rod 8 is fixedly arranged at the bottom end of the rotating shaft 7, a flat plate 11 is fixedly installed on the side of the reactor body 1, a protective mechanism 12 is fixedly installed on the surface of the flat plate 11, and a feed valve 13 is clamped and installed on the top of the protective mechanism 12;

[0023] Furthermore, the protection mechanism 12 includes a shell 121, a liquid inlet 122 is provided at the top of the shell 121, a liquid outlet 123 is provided at the bottom of the shell 121, and a through pipe 124 is provided at a position near the top of the inner wall of the shell 121;

[0024] During operation, a liquid inlet 122 is provided at the top of the shell 121 and a liquid outlet 123 is provided at the bottom of the shell 121, so as to facilitate the drainage of the original liquid and increase the stability of the device during operation.

[0025] Furthermore, collars 125 are fixedly connected to both sides of the through pipe 124, a slide bar 126 is slidably installed inside the collar 125, a cover plate 127 is fixedly connected to the bottom of the slide bar 126, and the size of the cover plate 127 matches the size of the through pipe 124;

[0026] During operation, the cover plate 127 has a sealing effect on the through pipe 124 due to the structural design that the size of the cover plate 127 matches the size of the through pipe 124 .

[0027] Furthermore, a spring 128 is sleeved on the surface of the slide bar 126 near the upper part of the collar 125, and a sealing ring 129 is embedded on the surface of the cover plate 127;

[0028] During operation, the sealing performance of the device is enhanced by the spring 128 sleeved on the surface of the slide rod 126 and the sealing ring 129 embedded on the surface of the cover plate 127 .

[0029] Furthermore, a connection block 9 is fixedly connected to the inner wall of the reactor body 1, a conduit 10 is fixedly connected to the surface of the connection block 9, a protection mechanism 12 is mounted on one end of the conduit 10, and the other end of the conduit 10 is located at a position close to the center point at the bottom of the reactor body 1;

[0030] During operation, the structural design that the other end of the conduit 10 is located at the bottom of the reactor body 1 near the center point allows the raw materials to flow into the device from the bottom surface, reducing the situation where the raw materials drip into the device and cause a violent reaction due to a large drop.

[0031] Furthermore, a discharge valve 14 is fixedly connected to the bottom of the reactor body 1, and a support frame 2 is fixedly connected to the bottom surface of the reactor body 1;

[0032] During operation, the support frame 2 arranged around the bottom surface of the reactor body 1 increases the stability of the device.

[0033] Working principle: When preparing dapagliflozin drugs, first, the drug solution to be processed is added through the feed valve 13, and the drug solution enters the conduit 10 through the protective mechanism 12, and finally flows into the reactor body 1. After adding an appropriate amount of drug solution, the motor 6 is started by an external power supply, and the motor 6 drives the rotating shaft 7 to drive the stirring rod 8 to work. At the same time, the reaction solution is added through the feed valve 13. Since the sliding rod 126 is slidably sleeved in the rings 125 on both sides of the through pipe 124, and the surface of the sliding rod 126 is close to the top of the ring 125. The spring 128 is sleeved, the pressure of the reaction solution squeezes the cover plate 127 to drop, and flows into the bottom of the reactor body 1 through the conduit 10 to react with the drug solution. When a violent reaction occurs inside the device, the reaction solution in the conduit 10 rebounds the cover plate 127, causing the cover plate 127 to squeeze the through pipe 124, cutting off the supply of the reaction solution, and reducing the intensity of the solution rushing in the device.

[0034] The above shows and describes the basic principle, main features and advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments, and the above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, and these changes and improvements fall within the scope of the utility model to be protected.

Claims

1. A reaction device for preparing dapagliflozin with a protective function, comprising a reaction kettle body (1), characterized in that: A flange connection plate (3) is fixedly connected to the top of the reactor body (1), a top cover (4) is fixedly connected to the top of the flange connection plate (3), a fixed block (5) is fixedly connected to the top of the top cover (4), a motor (6) is fixedly mounted on the surface of the fixed block (5), a rotating shaft (7) is fixedly connected to the output end of the motor (6), a stirring rod (8) is fixedly arranged at the bottom end of the rotating shaft (7), a flat plate (11) is fixedly mounted on the side of the reactor body (1), a protective mechanism (12) is fixedly mounted on the surface of the flat plate (11), and a feed valve (13) is snap-fitted to the top of the protective mechanism (12).

2. A reaction device for preparing dapagliflozin with protective function according to claim 1, characterized in that: The protection mechanism (12) comprises a shell (121), a liquid inlet (122) is provided at the top of the shell (121), a liquid outlet (123) is provided at the bottom of the shell (121), and a through pipe (124) is provided on the inner wall of the shell (121) near the top.

3. A reaction device for preparing dapagliflozin with protective function according to claim 2, characterized in that: The two sides of the through pipe (124) are fixedly connected with a collar (125), the interior of the collar (125) is slidably mounted with a slide rod (126), the bottom of the slide rod (126) is fixedly connected with a cover plate (127), and the size of the cover plate (127) matches the size of the through pipe (124).

4. The reaction device for preparing dapagliflozin with protective function according to claim 3, characterized in that: A spring (128) is sleeved on the surface of the slide rod (126) near the upper part of the sleeve ring (125), and a sealing ring (129) is embedded on the surface of the cover plate (127).

5. The reaction device for preparing dapagliflozin with protective function according to claim 1, characterized in that: A connection block (9) is fixedly connected to the inner wall of the reactor body (1), a conduit (10) is fixedly connected to the surface of the connection block (9), a protective mechanism (12) is snap-fitted onto one end of the conduit (10), and the other end of the conduit (10) is located at a position close to the center point at the bottom of the reactor body (1).

6. The reaction device for preparing dapagliflozin with protective function according to claim 1, characterized in that: A discharge valve (14) is fixedly connected to the bottom of the reactor body (1), and a support frame (2) is fixedly connected to the bottom surface of the reactor body (1).

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